11p15.5

Sections: General Information - Query T1DMart for overlapping human marker information - Region Overview - Genes in LD Region - Signal Clouds - Publications

General Information Top Help

General Information: Available

Organism	Human
Points of Interest	rs689,rs7111341
Karyotype Band Location	11p15.5
Chromosomal Location (NCBI36)	Chr11:2025000-2264880
Region Size	0.24 Mb
Orthologous Regions	Mouse: Human 11p15.5 Ortholgous Region Rat: Human 11p15.5 Ortholgous Region
Genes in Region (6)	ASCL2, IGF2, IGF2AS, INS, INS-IGF2, TH

Query T1DMart for overlapping human marker information from T1DMart Top Help

Marker	Marker Source	Start	Strand	Peptide Shift	Gene Symbol (HGNC)	Gene ID (Entrez)	Amino Acid Position
rs56374010	dbSNP_130	2056080	+	C/S	LOC100134730	100134730	20
rs56289343	dbSNP_130	2056087	+	Y/X	LOC100134730	100134730	22
rs12993	dbSNP_130	2110796	-	K/N	IGF2	3481	180
rs1050342	dbSNP_130	2110818	-	P/Q	IGF2	3481	173
rs11545014	dbSNP_130	2110819	-	P/S	IGF2	3481	173
rs61732764	dbSNP_130	2110869	+	R/P	IGF2	3481	156
rs14367	dbSNP_130	2110976	-	K/N	IGF2	3481	120
rs12807478	dbSNP_130	2118531	+	P/S	IGF2AS	51214	28
rs17883406	dbSNP_130	2124063	+	S/I	IGF2AS	51214	106
rs17883142	dbSNP_130	2124080	+	P/T	IGF2AS	51214	112
rs1003483	dbSNP_130	2124119	+	F/V	IGF2AS	51214	125
rs1003484	dbSNP_130	2124194	+	T/A	IGF2AS	51214	150
rs10770125	dbSNP_130	2125590	+	L/P	INS-IGF2	723961	144
rs28933985	dbSNP_130	2137725	-	R/H	INS	3630	89
rs41301451	dbSNP_130	2137790	+	E/D	INS	3630	67
rs11557614	dbSNP_130	2138665	-	A/V	INS	3630	38
rs11557614	dbSNP_130	2138665	-	A/V	INS-IGF2	723961	38
rs13306444	dbSNP_130	2138711	-	A/T	INS	3630	23
rs13306444	dbSNP_130	2138711	-	A/T	INS-IGF2	723961	23
rs1800033	dbSNP_130	2142131	-	V/M	TH	7054	468
rs45471299	dbSNP_130	2142145	-	T/M	TH	7054	463
rs28934580	dbSNP_130	2144499	-	R/H	TH	7054	306
rs28934581	dbSNP_130	2144801	-	T/P	TH	7054	245
rs28934579	dbSNP_130	2145955	-	L/P	TH	7054	173
rs6356	dbSNP_130	2147527	-	V/M	TH	7054	81

Non-Synonymous SNPs in region dbSNP_130:

Region Overview Top Help

GBrowse Image: Available

An overview of the region is provided by GBrowse. Tracks shown include gene information and study-specific data:
D' (black) and r-squared (red) with genotyped SNP	Calculated using the HapMap CEU Founders population. D' data has been limited to those values where LOD score > 3
HapMap Recobination Data	Genome-wide recombination rate from Phase 2 HapMap estimated from phased haplotypes in HapMap Release 22 (NCBI 36). Units are in cM/Mb.
P-values, -log(p)	1 degree of freedom p-values, stratified by geographic location. Generated using snpMatrix with data from the T1DGC Meta-analysis study.

Genes in LD Region Top Help

Genes in LD Region: Available

Summary data derived from GWA meta analysis Barrett et al. LD regions were calculated using different r² and D' threshold values, and these regions were then examined for genes. The definition of a gene location includes a 3kb flanking region either side of the gene.

Marker Data

Region Data

Links

r² Threshold

D' Threshold

Region

Genes