10p15.1

Sections: General Information - Query T1DMart for overlapping human marker information - Region Overview - Genes in LD Region - Signal Clouds - Publications

General Information Top Help

General Information: Available

Organism	Human
Points of Interest	rs12722495,rs11594656,rs12251307
Karyotype Band Location	10p15.1
Chromosomal Location (NCBI36)	Chr10:6069732-6237542
Region Size	0.17 Mb
Genes in Region (3)	IL2RA, PFKFB3, RBM17

Query T1DMart for overlapping human marker information from T1DMart Top Help

Marker	Marker Source	Start	Strand	Peptide Shift	Gene Symbol (HGNC)	Gene ID (Entrez)	Amino Acid Position
rs12722712	dbSNP_130	6094845	-	I/T	IL2RA	3559	272
rs55841382	dbSNP_130	6103503	+	R/K	IL2RA	3559	176
rs74162095	dbSNP_130	6106233	-	V/A	IL2RA	3559	116
rs56054476	dbSNP_130	6106248	+	S/N	IL2RA	3559	111
rs36065822	dbSNP_130	6106307	+	T/I	IL2RA	3559	91
rs72650666	dbSNP_130	6106308	-	T/M	IL2RA	3559	91
rs55868253	dbSNP_130	6107983	+	D/H	IL2RA	3559	26
rs74162092	dbSNP_130	6144076	-	M/I	IL2RA	3559	15
rs11541848	dbSNP_130	6183267	+	L/I	RBM17	84991	51

Non-Synonymous SNPs in region dbSNP_130:

Region Overview Top Help

GBrowse Image: Available

An overview of the region is provided by GBrowse. Tracks shown include gene information and study-specific data:
D' (black) and r-squared (red) with genotyped SNP	Calculated using the HapMap CEU Founders population. D' data has been limited to those values where LOD score > 3
HapMap Recobination Data	Genome-wide recombination rate from Phase 2 HapMap estimated from phased haplotypes in HapMap Release 22 (NCBI 36). Units are in cM/Mb.
P-values, -log(p)	1 degree of freedom p-values, stratified by geographic location. Generated using snpMatrix with data from the T1DGC Meta-analysis study.

Genes in LD Region Top Help

Genes in LD Region: Available

Summary data derived from GWA meta analysis Barrett et al. LD regions were calculated using different r² and D' threshold values, and these regions were then examined for genes. The definition of a gene location includes a 3kb flanking region either side of the gene.

Marker Data

Region Data

Links

r² Threshold

D' Threshold

Region

Genes