1p13.2

General Information Top Help

General Information: Available

Organism	Human
Points of Interest	rs2476601
Karyotype Band Location	1p13.2
Chromosomal Location (GRCh37)	Chr1:113818477-114658477
Region Size	0.84 Mb
Orthologous Regions	Mouse: Human 1p13.2 Orthologous Region Rat: Human 1p13.2 Orthologous Region
Genes in Region (11)	AP4B1, BCL2L15, DCLRE1B, HIPK1, LOC100287722, MAGI3, OLFML3, PHTF1, PTPN22, RSBN1, SYT6

View this region in the Human T1D Regions table.

Query T1DMart for overlapping human marker information from T1DMart Top Help

Marker	Marker Source	Start	Strand	Peptide Shift	Gene Symbol (HGNC)	Gene ID (Entrez)	Amino Acid Position
rs143845236	dbSNP_134	113933933	+	H/R	MAGI3	260425	93
rs150051428	dbSNP_134	114128125	+	T/S	MAGI3	260425	224
rs146330033	dbSNP_134	114128161	+	L/V	MAGI3	260425	236
rs148694155	dbSNP_134	114128186	+	D/V	MAGI3	260425	244
rs149597924	dbSNP_134	114133195	+	Y/H	MAGI3	260425	285
rs145176805	dbSNP_134	114133198	+	M/V	MAGI3	260425	286
rs77976861	dbSNP_134	114157241	+	E/G	MAGI3	260425	346
rs41283512	dbSNP_134	114165485	+	R/Q	MAGI3	260425	410
rs145442738	dbSNP_134	114165506	+	T/I	MAGI3	260425	417
rs148115675	dbSNP_134	114184682	+	V/I	MAGI3	260425	504
rs150620203	dbSNP_134	114184692	+	I/T	MAGI3	260425	507
rs142925500	dbSNP_134	114184716	+	N/S	MAGI3	260425	515
rs149386339	dbSNP_134	114184827	+	G/D	MAGI3	260425	552
rs140227167	dbSNP_134	114185096	+	F/L	MAGI3	260425	642
rs146878815	dbSNP_134	114186368	+	P/L	MAGI3	260425	657
rs149171641	dbSNP_134	114189198	+	S/P	MAGI3	260425	697
rs142998380	dbSNP_134	114193691	+	R/H	MAGI3	260425	768
rs143698690	dbSNP_134	114196521	+	R/Q	MAGI3	260425	837
rs144491494	dbSNP_134	114196553	+	E/K	MAGI3	260425	848
rs141038054	dbSNP_134	114201801	+	S/F	MAGI3	260425	910
rs150230904	dbSNP_134	114214359	+	H/L	MAGI3	260425	940
rs141608933	dbSNP_134	114214370	+	P/S	MAGI3	260425	944
rs138270035	dbSNP_134	114214371	+	P/L	MAGI3	260425	944
rs115953359	dbSNP_134	114214380	+	T/I	MAGI3	260425	947
rs141257481	dbSNP_134	114214442	+	H/N	MAGI3	260425	968
rs145947128	dbSNP_134	114215353	+	R/Q	MAGI3	260425	1012
rs150071766	dbSNP_134	114223955	+	H/Y	MAGI3	260425	1109
rs142409909	dbSNP_134	114224848	+	G/S	MAGI3	260425	1115
rs72990405	dbSNP_134	114224861	+	Y/S	MAGI3	260425	1119
rs141671759	dbSNP_134	114224863	+	V/M	MAGI3	260425	1120
rs138648427	dbSNP_134	114243565	+	Q/X	PHTF1	10745	633
rs145476172	dbSNP_134	114248568	+	C/R	PHTF1	10745	539
rs1141014	dbSNP_134	114248597	-	L/W	PHTF1	10745	529
rs145965579	dbSNP_134	114248625	+	A/S	PHTF1	10745	520
rs148623704	dbSNP_134	114248690	+	R/H	PHTF1	10745	498
rs140005268	dbSNP_134	114248691	+	R/C	PHTF1	10745	498
rs79135507	dbSNP_134	114248712	+	P/T	PHTF1	10745	491
rs147938311	dbSNP_134	114248714	+	F/S	PHTF1	10745	490
rs140067418	dbSNP_134	114248774	+	Y/F	PHTF1	10745	470
rs147693102	dbSNP_134	114248781	+	N/Y	PHTF1	10745	468
rs145541451	dbSNP_134	114249302	+	R/X	PHTF1	10745	438
rs36076018	dbSNP_134	114253006	+	D/R	PHTF1	10745	380
rs148397701	dbSNP_134	114253027	+	R/H	PHTF1	10745	373
rs147533901	dbSNP_134	114254433	+	C/G	PHTF1	10745	328
rs145726957	dbSNP_134	114255952	+	M/I	PHTF1	10745	244
rs61730007	dbSNP_134	114255975	+	Q/K	PHTF1	10745	237
rs79904100	dbSNP_134	114267402	+	W/L	PHTF1	10745	201
rs61817585	dbSNP_134	114269049	+	R/L	PHTF1	10745	160
rs143415786	dbSNP_134	114269077	+	T/S	PHTF1	10745	151
rs138550041	dbSNP_134	114269154	+	I/R	PHTF1	10745	125
rs35311195	dbSNP_134	114269155	+	I/V	PHTF1	10745	125
rs111490062	dbSNP_134	114280797	+	N/S	PHTF1	10745	89
rs78000844	dbSNP_134	114280825	+	R/X	PHTF1	10745	80
rs146537741	dbSNP_134	114280839	+	R/Q	PHTF1	10745	75
rs148874264	dbSNP_134	114300376	+	I/T	PHTF1	10745	16
rs77659803	dbSNP_134	114301286	+	K/E	PHTF1	10745	14
rs3211282	dbSNP_134	114308609	-	S/Y	RSBN1	54665	801
rs138634440	dbSNP_134	114308706	+	Q/X	RSBN1	54665	769
rs149404041	dbSNP_134	114308772	+	C/R	RSBN1	54665	747
rs139632000	dbSNP_134	114308844	+	G/R	RSBN1	54665	723
rs145591703	dbSNP_134	114310875	+		RSBN1	54665	599
rs34462362	dbSNP_134	114319962	+	P/P	RSBN1	54665	509
rs145853951	dbSNP_134	114340206	+	M/V	RSBN1	54665	386
rs141121877	dbSNP_134	114340340	+	Q/R	RSBN1	54665	341
rs150462475	dbSNP_134	114340423	+	K/N	RSBN1	54665	313
rs41283514	dbSNP_134	114340502	+	R/H	RSBN1	54665	287
rs140048385	dbSNP_134	114340551	+	L/F	RSBN1	54665	271
rs144657133	dbSNP_134	114354338	+	K/E	RSBN1	54665	233
rs142666867	dbSNP_134	114354364	+	G/A	RSBN1	54665	224
rs116046617	dbSNP_134	114354496	+	A/V	RSBN1	54665	180
rs150300706	dbSNP_134	114354551	+	L/V	RSBN1	54665	162
rs138448231	dbSNP_134	114354809	+	P/S	RSBN1	54665	76
rs113435991	dbSNP_134	114354812	+	K/E	RSBN1	54665	75
rs139244607	dbSNP_134	114354932	+	G/R	RSBN1	54665	35
rs41313296	dbSNP_134	114362225	+	N/I	PTPN22	26191	778
rs140698521	dbSNP_134	114367793	+	S/N	PTPN22	26191	751
rs56048322	dbSNP_134	114372214	-	K/N	PTPN22	26191	750
rs74163663	dbSNP_134	114372222	-	R/G	PTPN22	26191	748
rs143703692	dbSNP_134	114372578	+	D/E	PTPN22	26191	709
rs147233796	dbSNP_134	114372624	+	P/L	PTPN22	26191	694
rs142861258	dbSNP_134	114372645	+	H/L	PTPN22	26191	687
rs74111772	dbSNP_134	114375747	+	R/Q	PTPN22	26191	680
rs74163661	dbSNP_134	114377006	-	I/M	PTPN22	26191	650
rs146655207	dbSNP_134	114377035	+	S/P	PTPN22	26191	641
rs74163660	dbSNP_134	114377561	-	P/R	PTPN22	26191	622
rs2476601	dbSNP_134	114377568	+	R/W	PTPN22	26191	620
rs138223016	dbSNP_134	114377610	+	A/S	PTPN22	26191	606
rs61757796	dbSNP_134	114380241	+	S/L	PTPN22	26191	594
rs74163659	dbSNP_134	114380295	-	S/C	PTPN22	26191	576
rs114092230	dbSNP_134	114380395	+	S/G	PTPN22	26191	543
rs142902754	dbSNP_134	114380404	+	W/R	PTPN22	26191	540
rs74163657	dbSNP_134	114380439	-	Y/C	PTPN22	26191	528
rs150552386	dbSNP_134	114380469	+	H/R	PTPN22	26191	518
rs139083120	dbSNP_134	114380578	+	V/I	PTPN22	26191	482
rs146517005	dbSNP_134	114380639	+	K/N	PTPN22	26191	461
rs72650672	dbSNP_134	114380656	-	Q/E	PTPN22	26191	456
rs112191110	dbSNP_134	114380682	+	T/I	PTPN22	26191	447
rs74163655	dbSNP_134	114380692	-	I/L	PTPN22	26191	444
rs112873647	dbSNP_134	114380743	+	S/SI	PTPN22	26191	426
rs77913785	dbSNP_134	114380858	+	D/E	PTPN22	26191	388
rs138092829	dbSNP_134	114380886	+	D/G	PTPN22	26191	379
rs72650671	dbSNP_134	114380914	-	H/N	PTPN22	26191	370
rs141677022	dbSNP_134	114380944	+	E/K	PTPN22	26191	360
rs146211793	dbSNP_134	114381166	+	S/I	PTPN22	26191	331
rs141632902	dbSNP_134	114381181	+	P/L	PTPN22	26191	326
rs72483511	dbSNP_134	114391248	-	E/X	PTPN22	26191	277
rs72650670	dbSNP_134	114394681	-	R/W	PTPN22	26191	266
rs33996649	dbSNP_134	114394689	+	R/Q	PTPN22	26191	263
rs143665827	dbSNP_134	114394690	+	R/W	PTPN22	26191	263
rs138719022	dbSNP_134	114397554	+	S/G	PTPN22	26191	220
rs145405400	dbSNP_134	114397562	+	E/V	PTPN22	26191	217
rs61738614	dbSNP_134	114397595	+	L/R	PTPN22	26191	206
rs74163647	dbSNP_134	114397610	-	S/F	PTPN22	26191	201
rs34590413	dbSNP_134	114397665	+	R/X	PTPN22	26191	183
rs143887079	dbSNP_134	114399180	+	S/C	PTPN22	26191	157
rs115552198	dbSNP_134	114399229	+	R/C	PTPN22	26191	141
rs140976677	dbSNP_134	114401115	+	W/X	PTPN22	26191	118
rs144833744	dbSNP_134	114401662	+	D/N	PTPN22	26191	79
rs140006258	dbSNP_134	114401683	+	E/K	PTPN22	26191	72
rs74163642	dbSNP_134	114401685	-	V/A	PTPN22	26191	71
rs145473954	dbSNP_134	114414169	+	N/S	PTPN22	26191	26
rs114942995	dbSNP_134	114424416	+	F/L	BCL2L15	440603	151
rs114959448	dbSNP_134	114424424	+	R/W	BCL2L15	440603	149
rs138414265	dbSNP_134	114424433	+	Q/X	BCL2L15	440603	146
rs116085462	dbSNP_134	114424562	+	D/N	BCL2L15	440603	103
rs1217381	dbSNP_134	114424601	+	D/N	BCL2L15	440603	90
rs114941235	dbSNP_134	114424609	+	I/T	BCL2L15	440603	87
rs75493886	dbSNP_134	114429213	+	N/K	BCL2L15	440603	65
rs78559267	dbSNP_134	114429248	+	A/S	BCL2L15	440603	54
rs146778119	dbSNP_134	114429886	+	D/N	BCL2L15	440603	38
rs79050956	dbSNP_134	114437707	+	I/V	AP4B1	10717	734
rs11349	dbSNP_134	114437737	+	I/F	AP4B1	10717	724
rs148223090	dbSNP_134	114437743	+	S/G	AP4B1	10717	722
rs79922740	dbSNP_134	114437779	+	V/M	AP4B1	10717	710
rs137886060	dbSNP_134	114437824	+	T/A	AP4B1	10717	695
rs148748734	dbSNP_134	114438064	+	S/A	AP4B1	10717	615
rs71744623	dbSNP_134	114438117	+		AP4B1	10717	597
rs75705876	dbSNP_134	114438403	+	K/X	AP4B1	10717	590
rs114734921	dbSNP_134	114438448	+	I/V	AP4B1	10717	575
rs149723440	dbSNP_134	114438528	+	P/L	AP4B1	10717	548
rs78045846	dbSNP_134	114438639	+	V/G	AP4B1	10717	511
rs145551290	dbSNP_134	114438882	+	I/T	AP4B1	10717	503
rs147573619	dbSNP_134	114438893	+	L/F	AP4B1	10717	499
rs145722506	dbSNP_134	114438925	+	A/S	AP4B1	10717	489
rs149272848	dbSNP_134	114438927	+	P/H	AP4B1	10717	488
rs1217401	dbSNP_134	114438951	+	L/S	AP4B1	10717	480
rs142209254	dbSNP_134	114439045	+	R/X	AP4B1	10717	449
rs139657454	dbSNP_134	114440512	+	A/T	AP4B1	10717	418
rs145803736	dbSNP_134	114440547	+	R/Q	AP4B1	10717	406
rs145182838	dbSNP_134	114441349	+	I/V	AP4B1	10717	397
rs138042690	dbSNP_134	114441397	+	Q/E	AP4B1	10717	381
rs143389123	dbSNP_134	114442558	+	A/V	AP4B1	10717	361
rs140665228	dbSNP_134	114442582	+	R/Q	AP4B1	10717	353
rs138335735	dbSNP_134	114442583	+	R/X	AP4B1	10717	353
rs150622512	dbSNP_134	114442598	+	V/M	AP4B1	10717	348
rs142732858	dbSNP_134	114442672	+	S/L	AP4B1	10717	323
rs149335605	dbSNP_134	114442673	+	S/T	AP4B1	10717	323
rs111785152	dbSNP_134	114442742	+	V/L	AP4B1	10717	300
rs140090271	dbSNP_134	114442786	+	C/Y	AP4B1	10717	285
rs145820731	dbSNP_134	114442835	+	V/I	AP4B1	10717	269
rs143286419	dbSNP_134	114442873	+	T/I	AP4B1	10717	256
rs141417436	dbSNP_134	114442885	+	V/A	AP4B1	10717	252
rs138216814	dbSNP_134	114442970	+	R/C	AP4B1	10717	224
rs147200873	dbSNP_134	114442988	+	V/L	AP4B1	10717	218
rs149705131	dbSNP_134	114443858	+	R/Q	AP4B1	10717	206
rs144490934	dbSNP_134	114443969	+	R/H	AP4B1	10717	169
rs147043117	dbSNP_134	114444457	+	R/Q	AP4B1	10717	130
rs143769705	dbSNP_134	114444473	+	I/V	AP4B1	10717	125
rs75117963	dbSNP_134	114444484	+	I/K	AP4B1	10717	121
rs138880168	dbSNP_134	114444488	+	Y/N	AP4B1	10717	120
rs150762437	dbSNP_134	114445270	+	C/R	AP4B1	10717	110
rs74361335	dbSNP_134	114445279	+	R/W	AP4B1	10717	107
rs149478319	dbSNP_134	114445351	+	A/P	AP4B1	10717	83
rs148787137	dbSNP_134	114445422	+	T/S	AP4B1	10717	59
rs151293980	dbSNP_134	114445423	+	T/A	AP4B1	10717	59
rs147059410	dbSNP_134	114448255	+	W/S	DCLRE1B	64858	16
rs142343310	dbSNP_134	114448269	+	A/T	DCLRE1B	64858	21
rs138654405	dbSNP_134	114448279	+	A/V	DCLRE1B	64858	24
rs143565817	dbSNP_134	114448333	+	S/T	DCLRE1B	64858	42
rs28381069	dbSNP_134	114448345	+	R/L	DCLRE1B	64858	46
rs141544518	dbSNP_134	114448365	+	I/V	DCLRE1B	64858	53
rs11552449	dbSNP_134	114448389	+	H/D	DCLRE1B	64858	61
rs11102700	dbSNP_134	114449622	+	S/F	DCLRE1B	64858	65
rs11552448	dbSNP_134	114449642	+	L/M	DCLRE1B	64858	72
rs144806903	dbSNP_134	114449646	+	E/A	DCLRE1B	64858	73
rs11552447	dbSNP_134	114449670	+	P/H	DCLRE1B	64858	81
rs138768729	dbSNP_134	114449736	+	S/F	DCLRE1B	64858	103
rs34762757	dbSNP_134	114450657	+		DCLRE1B	64858	128
rs140411676	dbSNP_134	114450669	+	A/P	DCLRE1B	64858	132
rs141962323	dbSNP_134	114450689	+	Q/H	DCLRE1B	64858	138
rs150374247	dbSNP_134	114450747	+	R/X	DCLRE1B	64858	158
rs141015184	dbSNP_134	114450759	+	A/T	DCLRE1B	64858	162
rs138603501	dbSNP_134	114450783	+	R/X	DCLRE1B	64858	170
rs139388793	dbSNP_134	114453918	+	M/T	DCLRE1B	64858	235
rs145569979	dbSNP_134	114454061	+	R/C	DCLRE1B	64858	283
rs143568469	dbSNP_134	114454062	+	R/H	DCLRE1B	64858	283
rs145730345	dbSNP_134	114454112	+	R/W	DCLRE1B	64858	300
rs142747676	dbSNP_134	114454362	+	A/V	DCLRE1B	64858	383
rs141081316	dbSNP_134	114454397	+	R/W	DCLRE1B	64858	395
rs146482651	dbSNP_134	114454398	+	R/Q	DCLRE1B	64858	395
rs141159471	dbSNP_134	114454400	+	I/F	DCLRE1B	64858	396
rs150322296	dbSNP_134	114454458	+	F/S	DCLRE1B	64858	415
rs138564195	dbSNP_134	114454565	+	I/V	DCLRE1B	64858	451
rs28381079	dbSNP_134	114454598	+	D/N	DCLRE1B	64858	462
rs35183203	dbSNP_134	114454706	+	R/E	DCLRE1B	64858	498
rs140911649	dbSNP_134	114454722	+	K/T	DCLRE1B	64858	503
rs35397235	dbSNP_134	114454742	+	N/Y	DCLRE1B	64858	510
rs35324789	dbSNP_134	114483022	+	Q/R	HIPK1	204851	6
rs141245432	dbSNP_134	114483471	+		HIPK1	204851	156
rs140342055	dbSNP_134	114483544	+	H/R	HIPK1	204851	180
rs80160038	dbSNP_134	114483668	+	L/F	HIPK1	204851	221
rs150961452	dbSNP_134	114483768	+	Y/H	HIPK1	204851	255
rs74426646	dbSNP_134	114483851	+	N/K	HIPK1	204851	282
rs34335651	dbSNP_134	114483933	+	G/C	HIPK1	204851	310
rs140021280	dbSNP_134	114498240	+	Y/F	HIPK1	204851	459
rs114411909	dbSNP_134	114499892	+	N/S	HIPK1	204851	580
rs114046588	dbSNP_134	114500694	+	V/I	HIPK1	204851	588
rs57585637	dbSNP_134	114500734	+	S/F	HIPK1	204851	601
rs147784034	dbSNP_134	114500748	+	D/N	HIPK1	204851	606
rs141561706	dbSNP_134	114505011	+	Q/P	HIPK1	204851	685
rs17853139	dbSNP_134	114506067	+	P/Q	HIPK1	204851	721
rs142674370	dbSNP_134	114508845	+	A/T	HIPK1	204851	778
rs114325298	dbSNP_134	114512582	+	G/R	HIPK1	204851	926
rs114322315	dbSNP_134	114512583	+	G/V	HIPK1	204851	926
rs147800588	dbSNP_134	114512651	+	L/V	HIPK1	204851	949
rs145053914	dbSNP_134	114512664	+	Y/S	HIPK1	204851	953
rs149016587	dbSNP_134	114512670	+	T/I	HIPK1	204851	955
rs141047620	dbSNP_134	114512693	+	G/S	HIPK1	204851	963
rs114387016	dbSNP_134	114512744	+	T/A	HIPK1	204851	980
rs146312493	dbSNP_134	114512779	+	K/N	HIPK1	204851	991
rs114944075	dbSNP_134	114514475	+	A/T	HIPK1	204851	1015
rs148680235	dbSNP_134	114514530	+	A/V	HIPK1	204851	1033
rs147397910	dbSNP_134	114514536	+	R/H	HIPK1	204851	1035
rs113267891	dbSNP_134	114514577	+	V/L	HIPK1	204851	1049
rs12568463	dbSNP_134	114514598	+	L/F	HIPK1	204851	1056
rs150942801	dbSNP_134	114514619	+	V/I	HIPK1	204851	1063
rs56401016	dbSNP_134	114514643	+	L/V	HIPK1	204851	1071
rs17853522	dbSNP_134	114515662	+	A/V	HIPK1	204851	1054
rs138660116	dbSNP_134	114515767	+	P/L	HIPK1	204851	1089
rs34966241	dbSNP_134	114515968	+	V/A	HIPK1	204851	1156
rs139657411	dbSNP_134	114515971	+	P/R	HIPK1	204851	1157
rs150473583	dbSNP_134	114515994	+	L/F	HIPK1	204851	1165
rs142071670	dbSNP_134	114516067	+	R/Q	HIPK1	204851	1189
rs140198710	dbSNP_134	114516078	+	I/V	HIPK1	204851	1193
rs11553080	dbSNP_134	114522977	+	D/E	OLFML3	56944	46
rs140666123	dbSNP_134	114523006	+	R/Q	OLFML3	56944	56
rs144544470	dbSNP_134	114523069	+	R/T	OLFML3	56944	77
rs145257286	dbSNP_134	114523113	+	R/W	OLFML3	56944	92
rs138164881	dbSNP_134	114523585	+	I/V	OLFML3	56944	139
rs147669432	dbSNP_134	114523681	+	V/M	OLFML3	56944	171
rs11553081	dbSNP_134	114523704	+	D/E	OLFML3	56944	178
rs35317518	dbSNP_134	114523729	+	R/S	OLFML3	56944	187
rs139529930	dbSNP_134	114523753	+	A/S	OLFML3	56944	195
rs140675105	dbSNP_134	114523838	+	R/Q	OLFML3	56944	223
rs151084386	dbSNP_134	114523963	+	P/A	OLFML3	56944	265
rs112468878	dbSNP_134	114524027	+	V/A	OLFML3	56944	286
rs141551539	dbSNP_134	114524038	+	R/W	OLFML3	56944	290
rs143692625	dbSNP_134	114524141	+	A/V	OLFML3	56944	324
rs150666243	dbSNP_134	114524170	+	V/I	OLFML3	56944	334
rs146401239	dbSNP_134	114524192	+	S/T	OLFML3	56944	341
rs144472671	dbSNP_134	114524237	+	T/I	OLFML3	56944	356
rs144740096	dbSNP_134	114524275	+	Y/H	OLFML3	56944	369
rs142200631	dbSNP_134	114524296	+	R/C	OLFML3	56944	376
rs147910096	dbSNP_134	114524315	+	R/H	OLFML3	56944	382
rs142164979	dbSNP_134	114640393	+	A/T	SYT6	148281	406
rs148168972	dbSNP_134	114640467	+	R/H	SYT6	148281	381
rs150717431	dbSNP_134	114640468	+	R/C	SYT6	148281	381
rs149899868	dbSNP_134	114641717	+	R/X	SYT6	148281	370
rs144421687	dbSNP_134	114646270	+	V/G	SYT6	148281	297

Non-Synonymous SNPs in region dbSNP134:

Region Overview Top Help

(Human) GRCh37 - chr1:113818477..114658477 (840 kb) View in Genome Browser

An overview of the region is provided by GBrowse. Tracks shown include gene information and study-specific data:
Immune Disease Associated Variants	Variants shown to be associated with different auto-immune diseases
P-values, -log(p)	1 degree of freedom p-values, stratified by geographic location. Generated using snpMatrix with data from the T1DGC Meta-analysis study.
HapMap Recobination Data	Genome-wide recombination rate from Phase 2 HapMap estimated from phased haplotypes in HapMap Release 22 (NCBI 36). Units are in cM/Mb, coordinates have been projected to the current build.

Genes in LD Region Top Help

Genes in LD Region: Available

Summary data derived from GWA meta analysis Barrett et al. LD regions were calculated using different r² and D' threshold values, and these regions were then examined for genes. The definition of a gene location includes a 3kb flanking region either side of the gene.

Marker Data

Region Data

Links

r² Threshold

D' Threshold

Region

Genes

Marker	rs2476601
Chr	1
Position	114377568
Strand
P-Value	8.49e-85

N/A

0.5

chr1: 114075796..114528368

LOC100287722 AP4B1 PHTF1 HIPK1 MAGI3 PTPN22 BCL2L15 RSBN1 OLFML3 DCLRE1B

LD Region Feature File

LD File

0.4

N/A

chr1: 114173410..114450964

LOC100287722 AP4B1 PHTF1 MAGI3 PTPN22 BCL2L15 RSBN1 DCLRE1B

0.8

N/A

chr1: 114303808..114377568

PTPN22 RSBN1

N/A

Publications Top Help

Publications: 12

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew CG, Montgomery GW, Prescott NJ, Raychaudhuri S, Rotter JI, Schumm P, Sharma Y, Simms LA, Taylor KD, Whiteman D, Wijmenga C, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Cohen A, Colombel JF, Cottone M, Stronati L, Denson T, De Vos M, D'Inca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Gearry R, Glas J, Van Gossum A, Guthery SL, Halfvarson J, Verspaget HW, Hugot JP, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Libioulle C, Louis E, Mowat C, Newman W, Panés J, Phillips A, Proctor DD, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Seibold F, Steinhart AH, Stokkers PC, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan SR, Brant SR, Rioux JD, D'Amato M, Weersma RK, Kugathasan S, Griffiths AM, Mansfield JC, Vermeire S, Duerr RH, Silverberg MS, Satsangi J, Schreiber S, Cho JH, Annese V, Hakonarson H, Daly MJ, Parkes M
Nat Genet. 2010
PubMed ID: 21102463
Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.
Plant D, Flynn E, Mbarek H, Dieudé P, Cornelis F, Arlestig L, Dahlqvist SR, Goulielmos G, Boumpas DT, Sidiropoulos P, Johansen JS, Ørnbjerg LM, Hetland ML, Klareskog L, Filer A, Buckley CD, Raza K, Witte T, Schmidt RE, Worthington J
Ann Rheum Dis. 2010
PubMed ID: 20498205
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG, BIRAC Consortium, Barton A, Bowes J, Brouwer E, Burtt NP, Catanese JJ, Coblyn J, Coenen MJ, Costenbader KH, Criswell LA, Crusius JB, Cui J, de Bakker PI, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Lee AT, Liu X, Martin P, Morgan AW, Padyukov L, Posthumus MD, Radstake TR, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AH, van der Horst-Bruinsma IE, van der Schoot CE, van Riel PL, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth BP, YEAR Consortium, Wijmenga C, Karlson EW, Toes RE, de Vries N, Begovich AB, Worthington J, Siminovitch KA, Gregersen PK, Klareskog L, Plenge RM
Nat Genet. 2010
PubMed ID: 20453842
Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.
Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, Annese V, Dubinsky M, Rotter JI, Russell RK, Bradfield JP, Sleiman PM, Glessner JT, Walters T, Hou C, Kim C, Frackelton EC, Garris M, Doran J, Romano C, Catassi C, Van Limbergen J, Guthery SL, Denson L, Piccoli D, Silverberg MS, Stanley CA, Monos D, Wilson DC, Griffiths A, Grant SF, Satsangi J, Polychronakos C, Hakonarson H
Hum Mol Genet. 2010
PubMed ID: 20176734
Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.
Jin Y, Birlea SA, Fain PR, Gowan K, Riccardi SL, Holland PJ, Mailloux CM, Sufit AJ, Hutton SM, Amadi-Myers A, Bennett DC, Wallace MR, McCormack WT, Kemp EH, Gawkrodger DJ, Weetman AP, Picardo M, Leone G, Taïeb A, Jouary T, Ezzedine K, van Geel N, Lambert J, Overbeck A, Spritz RA
N Engl J Med. 2010
PubMed ID: 20410501
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Rantapää-Dahlqvist S, Baechler EC, Brown EE, Alarcón GS, Edberg JC, Ramsey-Goldman R, McGwin G, Reveille JD, Vilá LM, Kimberly RP, Manzi S, Petri MA, Lee A, Gregersen PK, Seldin MF, Rönnblom L, Criswell LA, Syvänen AC, Behrens TW, Graham RR
Nat Genet. 2009
PubMed ID: 19838195
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS, The Type 1 Diabetes Genetics Consortium
Nat Genet. 2009
PubMed ID: 19430480
Shared and distinct genetic variants in type 1 diabetes and celiac disease.
Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA
N Engl J Med. 2008
PubMed ID: 19073967
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, Belgian-French IBD Consortium, Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ
Nat Genet. 2008
PubMed ID: 18587394
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.
Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tîrgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA
Diabetes. 2004
PubMed ID: 15504986
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.
Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, Ardlie KG, Huang Q, Smith AM, Spoerke JM, Conn MT, Chang M, Chang SY, Saiki RK, Catanese JJ, Leong DU, Garcia VE, McAllister LB, Jeffery DA, Lee AT, Batliwalla F, Remmers E, Criswell LA, Seldin MF, Kastner DL, Amos CI, Sninsky JJ, Gregersen PK
Am J Hum Genet. 2004
PubMed ID: 15208781
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes.
Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M, MacMurray J, Meloni GF, Lucarelli P, Pellecchia M, Eisenbarth GS, Comings D, Mustelin T
Nat Genet. 2004
PubMed ID: 15004560

Signal Clouds Top Help

Signal Clouds: Available

View this page in archive site