T1DBase - A Bioinformatics Resource for Type 1 Diabetes Researchers

Gene Description:

IQ calmodulin-binding motif containing 1; IQ motif containing B1

Synonyms:

SLSN5, IQCB1, AV128382, PIQ, NPHP5, 6820449I09Rik, Iqcb1

Orthologs:

Human IQCB1 (protein-coding), Mouse Iqcb1 (protein-coding), Rat Iqcb1 (protein-coding)

Sources

Regions Overlapping this Feature: Rat: 1

Linkage Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Iddm17	Rat	chr11:19445919..87759784	68.31	594

(Human) GRCh37 - chr3:121488610..121553926 (65.32 kb) View in Genome Browser

(Mouse) NCBIM37 - chr16:36828471..36872807 (44.34 kb) View in Genome Browser

(Rat) RGSC3.4 - chr11:65708818..65763303 (54.48 kb) View in Genome Browser

HaemAtlas Expression Table for IQCB1:

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Table for IQCB1:

View all

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 10

Publications: 35

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
Li S, Wang L, Berman M, Kong YY, Dorf ME
Immunity. 2011
PubMed ID: 21903422
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.
Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M, Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK
Cell. 2011
PubMed ID: 21565611
Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy.
Cideciyan AV, Rachel RA, Aleman TS, Swider M, Schwartz SB, Sumaroka A, Roman AJ, Stone EM, Jacobson SG, Swaroop A
Hum Mol Genet. 2011
PubMed ID: 21245082
IQCB1 mutations in patients with leber congenital amaurosis.
Estrada-Cuzcano A, Koenekoop RK, Coppieters F, Kohl S, Lopez I, Collin RW, De Baere EB, Roeleveld D, Marek J, Bernd A, Rohrschneider K, van den Born LI, Meire F, Maumenee IH, Jacobson SG, Hoyng CB, Zrenner E, Cremers FP, den Hollander AI
Invest Ophthalmol Vis Sci. 2011
PubMed ID: 20881296
Allelic heterogeneity and genetic modifier loci contribute to clinical variation in males with X-linked retinitis pigmentosa due to RPGR mutations.
Fahim AT, Bowne SJ, Sullivan LS, Webb KD, Williams JT, Wheaton DK, Birch DG, Daiger SP
PLoS One. 2011
PubMed ID: 21857984
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Variations in NPHP5 in patients with nonsyndromic leber congenital amaurosis and Senior-Loken syndrome.
Stone EM, Cideciyan AV, Aleman TS, Scheetz TE, Sumaroka A, Ehlinger MA, Schwartz SB, Fishman GA, Traboulsi EI, Lam BL, Fulton AB, Mullins RF, Sheffield VC, Jacobson SG
Arch Ophthalmol. 2011
PubMed ID: 21220633
Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy.
Otto EA, Ramaswami G, Janssen S, Chaki M, Allen SJ, Zhou W, Airik R, Hurd TW, Ghosh AK, Wolf MT, Hoppe B, Neuhaus TJ, Bockenhauer D, Milford DV, Soliman NA, Antignac C, Saunier S, Johnson CA, Hildebrandt F, the GPN Study Group
J Med Genet. 2010
PubMed ID: 21068128
Nephronophthisis: disease mechanisms of a ciliopathy.
Hildebrandt F, Attanasio M, Otto E
J Am Soc Nephrol. 2009
PubMed ID: 19118152
Genetic and physical interaction between the NPHP5 and NPHP6 gene products.
Schäfer T, Pütz M, Lienkamp S, Ganner A, Bergbreiter A, Ramachandran H, Gieloff V, Gerner M, Mattonet C, Czarnecki PG, Sayer JA, Otto EA, Hildebrandt F, Kramer-Zucker A, Walz G
Hum Mol Genet. 2008
PubMed ID: 18723859
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
The DNA sequence, annotation and analysis of human chromosome 3.
Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA
Nature. 2006
PubMed ID: 16641997
Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers.
Luo X, He Q, Huang Y, Sheikh MS
Cancer Res. 2005
PubMed ID: 16322217
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis.
le Maire A, Weber T, Saunier S, Broutin I, Antignac C, Ducruix A, Dardel F
Proteins. 2005
PubMed ID: 15723349
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin.
Otto EA, Loeys B, Khanna H, Hellemans J, Sudbrak R, Fan S, Muerb U, O'Toole JF, Helou J, Attanasio M, Utsch B, Sayer JA, Lillo C, Jimeno D, Coucke P, De Paepe A, Reinhardt R, Klages S, Tsuda M, Kawakami I, Kusakabe T, Omran H, Imm A, Tippens M, Raymond PA, Hill J, Beales P, He S, Kispert A, Margolis B, Williams DS, Swaroop A, Hildebrandt F
Nat Genet. 2005
PubMed ID: 15723066
Characterization of the nephrocystin/nephrocystin-4 complex and subcellular localization of nephrocystin-4 to primary cilia and centrosomes.
Mollet G, Silbermann F, Delous M, Salomon R, Antignac C, Saunier S
Hum Mol Genet. 2005
PubMed ID: 15661758
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin.
Mollet G, Salomon R, Gribouval O, Silbermann F, Bacq D, Landthaler G, Milford D, Nayir A, Rizzoni G, Antignac C, Saunier S
Nat Genet. 2002
PubMed ID: 12244321
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement).
Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S
DNA Res. 1994
PubMed ID: 7584028
Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.
Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S
DNA Res. 1994
PubMed ID: 7584026

Model Organism Phenotype Links

	Human	Mouse	Rat
Entrez Gene	9657	320299	303915
EnsEMBL Gene(s)	ENSG00000173226	ENSMUSG00000022837	ENSRNOG00000038868
Unigene	Hs.604110	Mm.222934	Rn.107714
Homologene	IQCB1	Iqcb1	Iqcb1
OMIM	609237	N/A	N/A
GeneCards	IQCB1	N/A	N/A
Beta Cell Genomics	DT.318017 DT.91760722 DT.97844664	DT.485387 DT.91587535 DT.99839381	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	9657	320299	303915

Relevant resources:

Interactor	Interactor	Sources	Classification	Pubmed IDs
IQCB1	TRIM28	IntAct	empirical	21565611
IQCB1	CALCOCO2	IntAct	empirical	21565611
IQCB1	AKAP8	IntAct	empirical	21565611
IQCB1	DNAJA2	IntAct	empirical	21565611
IQCB1	TUBA1B	IntAct	empirical	21565611
IQCB1	BPNT1	IntAct	empirical	21565611
IQCB1	TUBB3	IntAct	empirical	21565611
IQCB1	TUBB4B	IntAct	empirical	21565611
IQCB1	CDIPT	IntAct	empirical	21565611
IQCB1	PGRMC2	IntAct	empirical	21565611
IQCB1	ACAA2	IntAct	empirical	21565611
IQCB1	IPO7	IntAct	empirical	21565611
IQCB1	ARFGEF2	IntAct	empirical	21565611
IQCB1	EXOC5	IntAct	empirical	21565611
IQCB1	HSPH1	IntAct	empirical	21565611
IQCB1	CPLX1	IntAct	empirical	21565611
IQCB1	GCN1L1	IntAct	empirical	21565611
IQCB1	RAB35	IntAct	empirical	21565611
IQCB1	NUDT3	IntAct	empirical	21565611
IQCB1	XPOT	IntAct	empirical	21565611
IQCB1	TWF2	IntAct	empirical	21565611
IQCB1	CKB	IntAct	empirical	21565611
IQCB1	PCMTD1	IntAct	empirical	21565611
IQCB1	CKM	IntAct	empirical	21565611
IQCB1	RAB3C	IntAct	empirical	21565611
IQCB1	DCD	IntAct	empirical	21565611
IQCB1	IQGAP3	IntAct	empirical	21565611
IQCB1	SVOPL	IntAct	empirical	21565611
IQCB1	CSE1L	IntAct	empirical	21565611
IQCB1	ANKAR	IntAct	empirical	21565611
IQCB1	LDHAL6A	IntAct	empirical	21565611
IQCB1	DDB1	IntAct	empirical	21565611
IQCB1	DNM1	IntAct	empirical	21565611
IQCB1	DPYSL2	IntAct	empirical	21565611
IQCB1	DSG1	IntAct	empirical	21565611
IQCB1	DSP	IntAct	empirical	21565611
IQCB1	ECH1	IntAct	empirical	21565611
IQCB1	EEF1A1	IntAct	empirical	21565611
IQCB1	EEF2	IntAct	empirical	21565611
IQCB1	EIF5A	IntAct	empirical	21565611
IQCB1	EMD	IntAct	empirical	21565611
IQCB1	SPATA24	IntAct	empirical	21565611
IQCB1	ENO3	IntAct	empirical	21565611
IQCB1	TUBB	IntAct	empirical	21565611
IQCB1	ALB	IntAct	empirical	21565611
IQCB1	GPC4	IntAct	empirical	21565611
IQCB1	ALDOA	IntAct	empirical	21565611
IQCB1	FH	IntAct	empirical	21565611
IQCB1	ITGA11	IntAct	empirical	21565611
IQCB1	MAPRE1	IntAct	empirical	21565611
IQCB1	CAND2	IntAct	empirical	21565611
IQCB1	PEG10	IntAct	empirical	21565611
IQCB1	FLNA	IntAct	empirical	21565611
IQCB1	FLNB	IntAct	empirical	21565611
IQCB1	FLNC	IntAct	empirical	21565611
IQCB1	PSME4	IntAct	empirical	21565611
IQCB1	RPGRIP1L	IntAct	empirical	21565611
IQCB1	NUP188	IntAct	empirical	21565611
IQCB1	DDAH1	IntAct	empirical	21565611
IQCB1	HSPBP1	IntAct	empirical	21565611
IQCB1	ATXN10	IntAct	empirical	21565611
IQCB1	GAPDH	IntAct	empirical	21565611
IQCB1	LTN1	IntAct	empirical	21565611
IQCB1	CNTNAP2	IntAct	empirical	21565611
IQCB1	ERC2	IntAct	empirical	21565611
IQCB1	NPHP4	IntAct	empirical	21565611
IQCB1	GAS8	IntAct	empirical	21565611
IQCB1	FBXO2	IntAct	empirical	21565611
IQCB1	GDI1	IntAct	empirical	21565611
IQCB1	GDI2	IntAct	empirical	21565611
IQCB1	INVS	IntAct	empirical	21565611
IQCB1	GLUD1	IntAct	empirical	21565611
IQCB1	GNAI1	IntAct	empirical	21565611
IQCB1	ANGPT2	IntAct	empirical	21565611
IQCB1	GRB10	IntAct	empirical	21565611
IQCB1	GSTM1	IntAct	empirical	21565611
IQCB1	GUK1	IntAct	empirical	21565611
IQCB1	HOOK2	IntAct	empirical	21565611
IQCB1	STRN3	IntAct	empirical	21565611
IQCB1	ANXA2	IntAct	empirical	21565611
IQCB1	HADHA	IntAct	empirical	21565611
IQCB1	HADHB	IntAct	empirical	21565611
IQCB1	HEXA	IntAct	empirical	21565611
IQCB1	UBE2K	IntAct	empirical	21565611
IQCB1	HK1	IntAct	empirical	21565611
IQCB1	HNRNPA2B1	IntAct	empirical	21565611
IQCB1	HNRNPF	IntAct	empirical	21565611
IQCB1	HNRNPH1	IntAct	empirical	21565611
IQCB1	HNRNPH2	IntAct	empirical	21565611
IQCB1	DNAJA1	IntAct	empirical	21565611
IQCB1	HSPA4	IntAct	empirical	21565611
IQCB1	HSPA5	IntAct	empirical	21565611
IQCB1	HSPA6	IntAct	empirical	21565611
IQCB1	HSPA8	IntAct	empirical	21565611
IQCB1	HSPA9	IntAct	empirical	21565611
IQCB1	HSPB1	IntAct	empirical	21565611
IQCB1	HSP90AA1	IntAct	empirical	21565611
IQCB1	HSP90AB1	IntAct	empirical	21565611
IQCB1	TUBB8	IntAct	empirical	21565611
IQCB1	IGF2R	IntAct	empirical	21565611
IQCB1	IGHG1	IntAct	empirical	21565611
IQCB1	IRAK2	BioGRID	empirical	21903422
IQCB1	JUP	IntAct	empirical	21565611
IQCB1	KPNB1	IntAct	empirical	21565611
IQCB1	IPO5	IntAct	empirical	21565611
IQCB1	KRT15	IntAct	empirical	21565611
IQCB1	HRNR	IntAct	empirical	21565611
IQCB1	FLG2	IntAct	empirical	21565611
IQCB1	LOX	IntAct	empirical	21565611
IQCB1	LPP	IntAct	empirical	21565611
IQCB1	MAD2L1	IntAct	empirical	21565611
IQCB1	MAG	IntAct	empirical	21565611
IQCB1	MAP1B	IntAct	empirical	21565611
IQCB1	MDH1	IntAct	empirical	21565611
IQCB1	ASPH	IntAct	empirical	21565611
IQCB1	MSR1	IntAct	empirical	21565611
IQCB1	MYH9	IntAct	empirical	21565611
IQCB1	MYH10	IntAct	empirical	21565611
IQCB1	MYO1C	IntAct	empirical	21565611
IQCB1	NAGLU	IntAct	empirical	21565611
IQCB1	HNRNPM	IntAct	empirical	21565611
IQCB1	NAP1L1	IntAct	empirical	21565611
IQCB1	NAP1L4	IntAct	empirical	21565611
IQCB1	NDUFA4	IntAct	empirical	21565611
IQCB1	NEFM	IntAct	empirical	21565611
IQCB1	ATP1A1	IntAct	empirical	21565611
IQCB1	NPHP1	IntAct	empirical	21565611
IQCB1	ATP2A2	IntAct	empirical	21565611
IQCB1	YBX1	IntAct	empirical	21565611
IQCB1	NUCB1	IntAct	empirical	21565611
IQCB1	ATP5A1	IntAct	empirical	21565611
IQCB1	OXCT1	IntAct	empirical	21565611
IQCB1	PEBP1	IntAct	empirical	21565611
IQCB1	PAFAH1B1	IntAct	empirical	21565611
IQCB1	PRDX1	IntAct	empirical	21565611
IQCB1	GEMIN4	IntAct	empirical	21565611
IQCB1	ATP5C1	IntAct	empirical	21565611
IQCB1	PCBP1	IntAct	empirical	21565611
IQCB1	PCP4	IntAct	empirical	21565611
IQCB1	RAB14	IntAct	empirical	21565611
IQCB1	CAB39	IntAct	empirical	21565611
IQCB1	PFDN2	IntAct	empirical	21565611
IQCB1	PGAM1	IntAct	empirical	21565611
IQCB1	PGD	IntAct	empirical	21565611
IQCB1	PGK1	IntAct	empirical	21565611
IQCB1	SLC25A3	IntAct	empirical	21565611
IQCB1	PLEC	IntAct	empirical	21565611
IQCB1	ATP6V1G2	IntAct	empirical	21565611
IQCB1	LPCAT2	IntAct	empirical	21565611
IQCB1	MRPL16	IntAct	empirical	21565611
IQCB1	PCMTD2	IntAct	empirical	21565611
IQCB1	PPP3R1	IntAct	empirical	21565611
IQCB1	PRIM1	IntAct	empirical	21565611
IQCB1	PRIM2	IntAct	empirical	21565611
IQCB1	PRKACB	IntAct	empirical	21565611
IQCB1	IPO9	IntAct	empirical	21565611
IQCB1	EXOC1	IntAct	empirical	21565611
IQCB1	IFT122	IntAct	empirical	21565611
IQCB1	PRKDC	IntAct	empirical	21565611
IQCB1	PSMA1	IntAct	empirical	21565611
IQCB1	PSMA2	IntAct	empirical	21565611
IQCB1	PSMA3	IntAct	empirical	21565611
IQCB1	PSMA4	IntAct	empirical	21565611
IQCB1	PSMA5	IntAct	empirical	21565611
IQCB1	PSMA6	IntAct	empirical	21565611
IQCB1	PSMA7	IntAct	empirical	21565611
IQCB1	PSMB1	IntAct	empirical	21565611
IQCB1	PSMB2	IntAct	empirical	21565611
IQCB1	PSMB3	IntAct	empirical	21565611
IQCB1	PSMB4	IntAct	empirical	21565611
IQCB1	PSMB5	IntAct	empirical	21565611
IQCB1	PSMB6	IntAct	empirical	21565611
IQCB1	PSMB7	IntAct	empirical	21565611
IQCB1	WDR35	IntAct	empirical	21565611
IQCB1	EPB41L5	IntAct	empirical	21565611
IQCB1	MAGEE1	IntAct	empirical	21565611
IQCB1	PTPN11	IntAct	empirical	21565611
IQCB1	PTPN13	IntAct	empirical	21565611
IQCB1	SQRDL	IntAct	empirical	21565611
IQCB1	QDPR	IntAct	empirical	21565611
IQCB1	RAB1A	IntAct	empirical	21565611
IQCB1	RCN2	IntAct	empirical	21565611
IQCB1	ACTB	IntAct	empirical	21565611
IQCB1	EXOC4	IntAct	empirical	21565611
IQCB1	RNH1	IntAct	empirical	21565611
IQCB1	RIC8A	IntAct	empirical	21565611
IQCB1	RPGR	BioGRID	empirical	15723066
IQCB1	RRBP1	IntAct	empirical	21565611
IQCB1	MMS19	IntAct	empirical	21565611
IQCB1	SKP1	IntAct	empirical	21565611
IQCB1	SLC5A3	IntAct	empirical	21565611
IQCB1	BOLA2B	IntAct	empirical	21565611
IQCB1	PCP4L1	IntAct	empirical	21565611
IQCB1	FSCN1	IntAct	empirical	21565611
IQCB1	SPTAN1	IntAct	empirical	21565611
IQCB1	SPTBN1	IntAct	empirical	21565611
IQCB1	TRIM21	IntAct	empirical	21565611
IQCB1	STXBP1	IntAct	empirical	21565611
IQCB1	VAMP2	IntAct	empirical	21565611
IQCB1	SYN2	IntAct	empirical	21565611
IQCB1	TFRC	IntAct	empirical	21565611
IQCB1	THBS1	IntAct	empirical	21565611
IQCB1	TPI1	IntAct	empirical	21565611
IQCB1	CCT3	IntAct	empirical	21565611
IQCB1	TUBA4A	IntAct	empirical	21565611
IQCB1	HEATR7A	IntAct	empirical	21565611
IQCB1	TUBB2A	IntAct	empirical	21565611
IQCB1	TUFM	IntAct	empirical	21565611
IQCB1	UBC	BioGRID	empirical	21139048 21890473 21906983
IQCB1	UBE2V1	IntAct	empirical	21565611
IQCB1	UCHL1	IntAct	empirical	21565611
IQCB1	YWHAB	IntAct	empirical	21565611
IQCB1	TUBA1A	IntAct	empirical	21565611
IQCB1	CAD	IntAct	empirical	21565611
IQCB1	TMEM43	IntAct	empirical	21565611
IQCB1	CALB1	IntAct	empirical	21565611
IQCB1	FYCO1	IntAct	empirical	21565611
IQCB1	TUBA4B	IntAct	empirical	21565611
IQCB1	CEP290	IntAct	empirical	21565611
IQCB1	CALM2	HPRD	empirical	15723066
IQCB1	ACTN4	IntAct	empirical	21565611
IQCB1	CALU	IntAct	empirical	21565611
IQCB1	CDC45	IntAct	empirical	21565611
IQCB1	SH3BGRL2	IntAct	empirical	21565611
IQCB1	CRISPLD2	IntAct	empirical	21565611
IQCB1	FAR1	IntAct	empirical	21565611
IQCB1	MAP1LC3A	IntAct	empirical	20562859
IQCB1	TUBB6	IntAct	empirical	21565611
IQCB1	HIRIP3	IntAct	empirical	21565611
IQCB1	TUBA1C	IntAct	empirical	21565611
IQCB1	GEMIN2	IntAct	empirical	21565611
IQCB1	DYNLL1	IntAct	empirical	21565611
IQCB1	PEA15	IntAct	empirical	21565611
IQCB1	ACTN1	IntAct	empirical	21565611
IQCB1	SERPINH1	IntAct	empirical	21565611
IQCB1	SGPL1	IntAct	empirical	21565611
IQCB1	UBE3B	IntAct	empirical	21565611
IQCB1	CCT6A	IntAct	empirical	21565611
IQCB1	DNAJA3	IntAct	empirical	21565611
IQCB1	AIFM1	IntAct	empirical	21565611
IQCB1	DTD1	IntAct	empirical	21565611
IQCB1	CIAO1	IntAct	empirical	21565611
IQCB1	BAG2	IntAct	empirical	21565611
IQCB1	IQCB1	IntAct	empirical	21565611
IQCB1	KNTC1	IntAct	empirical	21565611
IQCB1	SEC16A	IntAct	empirical	21565611