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IER3

Gene Description:   immediate early response 3 Synonyms:   IEX-1L, AI663993, PRG1, Dif2, cI-3, MGC124532, IEX1, GLY96, IER3, gly96, Ier3, Iex1, DIF-2, IEX-1, Ler3, Prg1, DIF2 Orthologs:   Human IER3 (protein-coding), Mouse Ier3 (protein-coding), Rat Ier3 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Human-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
MHC	Human	chr6:29910021..33498585	3.59	688

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd24	Mouse	chr17:35340111..41438922	6.10	184

(Human) GRCh37 - chr6:30710976..30712331 (1.35 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr17:35958629..35959868 (1.24 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr20:3076568..3077772 (1.20 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for IER3: The IER3 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs IER3   MCL1   IntAct  empirical  15451437  IER3   PPP2CA   MINT  empirical  16456541  IER3   PPP2R5B   MINT  empirical  16456541  IER3   PPP2R5C   MINT  empirical  16456541  IER3   MAPK1   MINT  empirical  16456541  IER3   PRNP   IntAct  empirical  18482256  IER3   BAG6   IntAct  empirical  15451437  IER3   CAMLG   IntAct  empirical  15451437  IER3   TNFSF10   IntAct  empirical  15451437

View all

KEGG Network: None available   None available.

Biocarta: None available   None available.

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 6   Protein binding GO:0005515 Apoptosis GO:0006915 Anti-apoptosis GO:0006916 Anatomical structure morphogenesis GO:0009653 Membrane GO:0016020 Integral to membrane GO:0016021

	KEGG Network: None available
	Biocarta: None available
	Reactome: None available
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 6 Protein binding GO:0005515 Apoptosis GO:0006915 Anti-apoptosis GO:0006916 Anatomical structure morphogenesis GO:0009653 Membrane GO:0016020 Integral to membrane GO:0016021

Publications: 75

• Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis.
  Arlt A, Schäfer H
  Eur J Cell Biol. 2011
  PubMed ID: 21112119
   
  
• Early proliferation alteration and differential gene expression in human periodontal ligament cells subjected to cyclic tensile stress.
  Wang Y, Li Y, Fan X, Zhang Y, Wu J, Zhao Z
  Arch Oral Biol. 2011
  PubMed ID: 20934684
   
  
• Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.
  Trollmann R, Rehrauer H, Schneider C, Krischke G, Huemmler N, Keller S, Rascher W, Gassmann M
  Am J Physiol Regul Integr Comp Physiol. 2010
  PubMed ID: 20926767
   
  
• ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response.
  Pawlikowska P, Leray I, de Laval B, Guihard S, Kumar R, Rosselli F, Porteu F
  Cell Death Differ. 2010
  PubMed ID: 20467439
   
  
• Impaired 3',5'-cyclic adenosine monophosphate-mediated signaling in immediate early responsive gene X-1-deficient vascular smooth muscle cells.
  Shahid M, Shen L, Seldin DC, Lu B, Ustyugova IV, Chen X, Zapol WM, Wu MX
  Hypertension. 2010
  PubMed ID: 20713914
   
  
• Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
  Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Tevfik Dorak M
  Mol Hum Reprod. 2010
  PubMed ID: 20587610
   
  
• Enhanced susceptibility to Leishmania infection in resistant mice in the absence of immediate early response gene X-1.
  Akilov OE, Ustyugova IV, Zhi L, Hasan T, Wu MX
  J Immunol. 2009
  PubMed ID: 19923449
   
  
• TP53 R72P and MDM2 SNP309 polymorphisms in modification of childhood acute lymphoblastic leukemia susceptibility.
  Do TN, Ucisik-Akkaya E, Davis CF, Morrison BA, Dorak MT
  Cancer Genet Cytogenet. 2009
  PubMed ID: 19837266
   
  
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
  PLoS Genet. 2009
  PubMed ID: 19851445
   
  
• Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes.
  Steensma DP, Neiger JD, Porcher JC, Keats JJ, Bergsagel PL, Dennis TR, Knudson RA, Jenkins RB, Santana-Davila R, Kumar R, Ketterling RP
  Cancer Res. 2009
  PubMed ID: 19773435
   
  
• Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma.
  Ria R, Todoerti K, Berardi S, Coluccia AM, De Luisi A, Mattioli M, Ronchetti D, Morabito F, Guarini A, Petrucci MT, Dammacco F, Ribatti D, Neri A, Vacca A
  Clin Cancer Res. 2009
  PubMed ID: 19690192
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• IEX-1-induced cell death requires BIM and is modulated by MCL-1.
  Yoon S, Ha HJ, Kim YH, Won M, Park M, Ko JJ, Lee K, Bae J
  Biochem Biophys Res Commun. 2009
  PubMed ID: 19285955
   
  
• IEX-1 targets mitochondrial F1Fo-ATPase inhibitor for degradation.
  Shen L, Zhi L, Hu W, Wu MX
  Cell Death Differ. 2009
  PubMed ID: 19096392
   
  
• Differential gene expression of bone marrow-derived CD34+ cells is associated with survival of patients suffering from myelodysplastic syndrome.
  Prall WC, Czibere A, Grall F, Spentzos D, Steidl U, Giagounidis AA, Kuendgen A, Otu H, Rong A, Libermann TA, Germing U, Gattermann N, Haas R, Aivado M
  Int J Hematol. 2009
  PubMed ID: 19152102
   
  
• Overexpression of immediate early gene X-1 (IEX-1) enhances gamma-radiation-induced apoptosis of human glioma cell line, U87-MG.
  Yamashita K, Nakashima S, You F, Hayashi S, Iwama T
  Neuropathology. 2009
  PubMed ID: 18564103
   
  
• Protein microarray analysis identifies human cellular prion protein interactors.
  Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H
  Neuropathol Appl Neurobiol. 2009
  PubMed ID: 18482256
   
  
• The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition.
  Sebens Müerköster S, Rausch AV, Isberner A, Minkenberg J, Blaszczuk E, Witt M, Fölsch UR, Schmitz F, Schäfer H, Arlt A
  Oncogene. 2008
  PubMed ID: 17704804
   
  
• Prognostic significance of the immediate early response gene X-1 (IEX-1) expression in pancreatic cancer.
  Sasada T, Azuma K, Hirai T, Hashida H, Kanai M, Yanagawa T, Takabayashi A
  Ann Surg Oncol. 2008
  PubMed ID: 18026799
   
  
• Immediate early gene IEX-1 induces astrocytic differentiation of U87-MG human glioma cells.
  You F, Osawa Y, Hayashi S, Nakashima S
  J Cell Biochem. 2007
  PubMed ID: 16960879
   
  
• Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene.
  Corcoran JA, Hsu WL, Smiley JR
  J Virol. 2006
  PubMed ID: 16973576
   
  
• Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
  Shiina T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, Gojobori T, Inoko H, Bahram S
  Genetics. 2006
  PubMed ID: 16702430
   
  
• Distinct domains for anti- and pro-apoptotic activities of IEX-1.
  Shen L, Guo J, Santos-Berrios C, Wu MX
  J Biol Chem. 2006
  PubMed ID: 16567805
   
  
• BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
  Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
  PLoS Biol. 2006
  PubMed ID: 16602821
   
  
• B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK.
  Letourneux C, Rocher G, Porteu F
  EMBO J. 2006
  PubMed ID: 16456541
   
  
• Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene.
  Sommer SL, Berndt TJ, Frank E, Patel JB, Redfield MM, Dong X, Griffin MD, Grande JP, van Deursen JM, Sieck GC, Romero JC, Kumar R
  J Appl Physiol. 2006
  PubMed ID: 16166241
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• Immediate early gene X1 (IEX-1) is organized in subnuclear structures and partially co-localizes with promyelocytic leukemia protein in HeLa cells.
  Kruse ML, Arlt A, Sieke A, Grohmann F, Grossmann M, Minkenberg J, Fölsch UR, Schäfer H
  J Biol Chem. 2005
  PubMed ID: 15855159
   
  
• Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.
  Okada A, Kushima K, Aoki Y, Bialer M, Fujiwara M
  Birth Defects Res A Clin Mol Teratol. 2005
  PubMed ID: 15799026
   
  
• Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.
  Hsu WL, Saffran HA, Smiley JR
  J Virol. 2005
  PubMed ID: 15767410
   
  
• p73beta-Mediated apoptosis requires p57kip2 induction and IEX-1 inhibition.
  Gonzalez S, Perez-Perez MM, Hernando E, Serrano M, Cordon-Cardo C
  Cancer Res. 2005
  PubMed ID: 15781630
   
  
• Gene and alternative splicing annotation with AIR.
  Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
  Genome Res. 2005
  PubMed ID: 15632090
   
  
• Immediate early gene X-1 interacts with proteins that modulate apoptosis.
  Kumar R, Lutz W, Frank E, Im HJ
  Biochem Biophys Res Commun. 2004
  PubMed ID: 15451437
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• The genomic sequence and comparative analysis of the rat major histocompatibility complex.
  Hurt P, Walter L, Sudbrak R, Klages S, Müller I, Shiina T, Inoko H, Lehrach H, Günther E, Reinhardt R, Himmelbauer H
  Genome Res. 2004
  PubMed ID: 15060004
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
  PubMed ID: 15057822
   
  
• Immediate early gene X-1 (IEX-1), a hydroxytamoxifen regulated gene with increased stimulation in MCF-7 derived resistant breast cancer cells.
  Semlali A, Oliva J, Badia E, Pons M, Duchesne MJ
  J Steroid Biochem Mol Biol. 2004
  PubMed ID: 15120418
   
  
• Regulation of flotillin-1 in the establishment of NIH-3T3 cell-cell interactions.
  López-Casas PP, del Mazo J
  FEBS Lett. 2003
  PubMed ID: 14644419
   
  
• The DNA sequence and analysis of human chromosome 6.
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