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SYNGAP1

Gene Description:   synaptic Ras GTPase activating protein 1; synaptic Ras GTPase activating protein 1 homolog (rat) Synonyms:   RASA5, SYNGAP1, MRD5, DKFZp761G1421, RASA1, Syngap1, Gm1963, KIAA1938, SYNGAP, Syngap Orthologs:   Human SYNGAP1 (protein-coding), Mouse Syngap1 (protein-coding), Rat Syngap1 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD Human-Rat: HomoloGene, MGD, RGD Mouse-Rat: HomoloGene, MGD, RGD Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
MHC	Human	chr6:29910021..33498585	3.59	688

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd16	Mouse	chr17:26318983..29405394	3.09	82	3 no lod score

(Human) GRCh37 - chr6:33387847..33421466 (33.62 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr17:27078397..27107590 (29.19 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr20:5178523..5208449 (29.93 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas       no data   no data no data no data     no data   no data

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for SYNGAP1: The SYNGAP1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs SYNGAP1   OPTN   IntAct  empirical  20195357  SYNGAP1   DLG3   HPRD, MINT  empirical  9581761  16427633  SYNGAP1   DLG4   HPRD, MINT, IntAct  empirical  9581761  16054660  19455133  SYNGAP1   ESR2   IntAct  empirical  21182203  SYNGAP1   DLGAP4   HPRD  empirical  9620694  11487731  9581761  SYNGAP1   GRIN1   HPRD, MINT  empirical  10862698  16054660  SYNGAP1   GRIN2B   HPRD  empirical  9620694  SYNGAP1   GRIN2D   HPRD  empirical  10862698  SYNGAP1   KLHL17   MINT  empirical  16054660  SYNGAP1   KDR   HPRD  empirical  9405464  SYNGAP1   PDGFRB   HPRD  empirical  1374684  SYNGAP1   PDZK1   MINT  empirical  16054660  SYNGAP1   TRIP6   HPRD  empirical  11782456  SYNGAP1   CAMK2A   HPRD  empirical  15312654  12951199  11278737  15358237  14970204  SYNGAP1   ULK1   HPRD  empirical  15014045  SYNGAP1   MPDZ   HPRD  empirical  15312654  SYNGAP1   ULK2   HPRD  empirical  15014045

View all

KEGG Network: None available   None available.

Biocarta: None available   None available.

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 9   Ras GTPase activator activity GO:0005099 Intracellular GO:0005622 Cytoplasm GO:0005737 Signal transduction GO:0007165 SH3 domain binding GO:0017124 Intrinsic to internal side of plasma membrane GO:0031235 Positive regulation of Ras GTPase activity GO:0032320 Negative regulation of Ras protein signal transduction GO:0046580 Regulation of small GTPase mediated signal transduction GO:0051056

	KEGG Network: None available
	Biocarta: None available
	Reactome: None available
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 9 Ras GTPase activator activity GO:0005099 Intracellular GO:0005622 Cytoplasm GO:0005737 Signal transduction GO:0007165 SH3 domain binding GO:0017124 Intrinsic to internal side of plasma membrane GO:0031235 Positive regulation of Ras GTPase activity GO:0032320 Negative regulation of Ras protein signal transduction GO:0046580 Regulation of small GTPase mediated signal transduction GO:0051056

Publications: 49

• De novo SYNGAP1 mutations in nonsyndromic intellectual disability and autism.
  Hamdan FF, Daoud H, Piton A, Gauthier J, Dobrzeniecka S, Krebs MO, Joober R, Lacaille JC, Nadeau A, Milunsky JM, Wang Z, Carmant L, Mottron L, Beauchamp MH, Rouleau GA, Michaud JL
  Biol Psychiatry. 2011
  PubMed ID: 21237447
   
  
• De novo autosomal dominant mutation in SYNGAP1.
  Cook EH
  Autism Res. 2011
  PubMed ID: 21480541
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• A de novo paradigm for mental retardation.
  Vissers LE, de Ligt J, Gilissen C, Janssen I, Steehouwer M, de Vries P, van Lier B, Arts P, Wieskamp N, del Rosario M, van Bon BW, Hoischen A, de Vries BB, Brunner HG, Veltman JA
  Nat Genet. 2010
  PubMed ID: 21076407
   
  
• Functional impact of global rare copy number variation in autism spectrum disorders.
  Pinto D, Pagnamenta AT, Klei L, Anney R, Merico D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Almeida J, Bacchelli E, Bader GD, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Bryson SE, Carson AR, Casallo G, Casey J, Chung BH, Cochrane L, Corsello C, Crawford EL, Crossett A, Cytrynbaum C, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green A, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Pilorge M, Piven J, Ponting CP, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Sequeira AF, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stein O, Sykes N, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Webber C, Weksberg R, Wing K, Wittemeyer K, Wood S, Wu J, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Devlin B, Ennis S, Gallagher L, Geschwind DH, Gill M, Haines JL, Hallmayer J, Miller J, Monaco AP, Nurnberger JI, Paterson AD, Pericak-Vance MA, Schellenberg GD, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Scherer SW, Sutcliffe JS, Betancur C
  Nature. 2010
  PubMed ID: 20531469
   
  
• [De novo mutations in SYNGAP1 associated with non-syndromic mental retardation]
  Hamdan FF, Gauthier J, Rouleau GA, Michaud JL
  Med Sci (Paris). 2010
  PubMed ID: 20188038
   
  
• Disruption of hippocampus-regulated behavioural and cognitive processes by heterozygous constitutive deletion of SynGAP.
  Muhia M, Yee BK, Feldon J, Markopoulos F, Knuesel I
  Eur J Neurosci. 2010
  PubMed ID: 20105235
   
  
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
  PLoS Genet. 2009
  PubMed ID: 19851445
   
  
• Appetitively motivated instrumental learning in SynGAP heterozygous knockout mice.
  Muhia M, Feldon J, Knuesel I, Yee BK
  Behav Neurosci. 2009
  PubMed ID: 19824778
   
  
• Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia.
  Funk AJ, Rumbaugh G, Harotunian V, McCullumsmith RE, Meador-Woodruff JH
  Neuroreport. 2009
  PubMed ID: 19483657
   
  
• Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia.
  Guo X, Hamilton PJ, Reish NJ, Sweatt JD, Miller CA, Rumbaugh G
  Neuropsychopharmacology. 2009
  PubMed ID: 19145222
   
  
• Age-related accumulation of Reelin in amyloid-like deposits.
  Knuesel I, Nyffeler M, Mormède C, Muhia M, Meyer U, Pietropaolo S, Yee BK, Pryce CR, LaFerla FM, Marighetto A, Feldon J
  Neurobiol Aging. 2009
  PubMed ID: 17904250
   
  
• Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation.
  Hamdan FF, Gauthier J, Spiegelman D, Noreau A, Yang Y, Pellerin S, Dobrzeniecka S, Côté M, Perreault-Linck E, Carmant L, D'Anjou G, Fombonne E, Addington AM, Rapoport JL, Delisi LE, Krebs MO, Mouaffak F, Joober R, Mottron L, Drapeau P, Marineau C, Lafrenière RG, Lacaille JC, Rouleau GA, Michaud JL, Synapse to Disease Group
  N Engl J Med. 2009
  PubMed ID: 19196676
   
  
• SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin.
  Carlisle HJ, Manzerra P, Marcora E, Kennedy MB
  J Neurosci. 2008
  PubMed ID: 19074040
   
  
• Differential distribution of synGAP alpha1 and synGAP beta isoforms in rat neurons.
  Moon IS, Sakagami H, Nakayama J, Suzuki T
  Brain Res. 2008
  PubMed ID: 18824155
   
  
• The MUPP1-SynGAPalpha protein complex does not mediate activity-induced LTP.
  Rama S, Krapivinsky G, Clapham DE, Medina I
  Mol Cell Neurosci. 2008
  PubMed ID: 18417361
   
  
• The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
  Pena V, Hothorn M, Eberth A, Kaschau N, Parret A, Gremer L, Bonneau F, Ahmadian MR, Scheffzek K
  EMBO Rep. 2008
  PubMed ID: 18323856
   
  
• The full-ORF clone resource of the German cDNA Consortium.
  Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blöcker H, Heubner D, Hoerlein A, Michel G, Wedler H, Köhrer K, Ottenwälder B, Poustka A, Wiemann S, Schupp I
  BMC Genomics. 2007
  PubMed ID: 17974005
   
  
• SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons.
  Rumbaugh G, Adams JP, Kim JH, Huganir RL
  Proc Natl Acad Sci U S A. 2006
  PubMed ID: 16537406
   
  
• Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice.
  Barnett MW, Watson RF, Vitalis T, Porter K, Komiyama NH, Stoney PN, Gillingwater TH, Grant SG, Kind PC
  J Neurosci. 2006
  PubMed ID: 16452659
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• Interactions between CAP70 and actinfilin are important for integrity of actin cytoskeleton structures in neurons.
  Chen Y, Li M
  Neuropharmacology. 2005
  PubMed ID: 16054660
   
  
• A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice.
  Turcotte K, Gauthier S, Tuite A, Mullick A, Malo D, Gros P
  J Exp Med. 2005
  PubMed ID: 15781580
   
  
• A role for synGAP in regulating neuronal apoptosis.
  Knuesel I, Elliott A, Chen HJ, Mansuy IM, Kennedy MB
  Eur J Neurosci. 2005
  PubMed ID: 15733080
   
  
• Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development.
  Porter K, Komiyama NH, Vitalis T, Kind PC, Grant SG
  Eur J Neurosci. 2005
  PubMed ID: 15673435
   
  
• Impaired SynGAP expression and long-term spatial learning and memory in hippocampal CA1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of A68930.
  Yang SN, Huang CB, Yang CH, Lai MC, Chen WF, Wang CL, Wu CL, Huang LT
  Neurosci Lett. 2004
  PubMed ID: 15500970
   
  
• SynGAP regulates spine formation.
  Vazquez LE, Chen HJ, Sokolova I, Knuesel I, Kennedy MB
  J Neurosci. 2004
  PubMed ID: 15470153
   
  
• SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation.
  Krapivinsky G, Medina I, Krapivinsky L, Gapon S, Clapham DE
  Neuron. 2004
  PubMed ID: 15312654
   
  
• Identification of novel phosphorylation sites on postsynaptic density proteins.
  Jaffe H, Vinade L, Dosemeci A
  Biochem Biophys Res Commun. 2004
  PubMed ID: 15358237
   
  
• Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.
  Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW
  Nat Biotechnol. 2004
  PubMed ID: 15146197
   
  
• Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II.
  Oh JS, Manzerra P, Kennedy MB
  J Biol Chem. 2004
  PubMed ID: 14970204
   
  
• PSD-95 promotes CaMKII-catalyzed serine phosphorylation of the synaptic RAS-GTPase activating protein SynGAP after transient brain ischemia in rat hippocampus.
  Song B, Yan XB, Zhang GY
  Brain Res. 2004
  PubMed ID: 15044063
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
  PubMed ID: 15057822
   
  
• Role of Unc51.1 and its binding partners in CNS axon outgrowth.
  Tomoda T, Kim JH, Zhan C, Hatten ME
  Genes Dev. 2004
  PubMed ID: 15014045
   
  
• Complete sequencing and characterization of 21,243 full-length human cDNAs.
  Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
  Nat Genet. 2004
  PubMed ID: 14702039
   
  
• The DNA sequence and analysis of human chromosome 6.
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