CAV1

Summary Top Help

Gene Description:

caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa

Synonyms:

BSCL3, CAV1, Cav1, CGL3, Cav, VIP21, MSTP085, Cav-1

Orthologs:

Human CAV1 (protein-coding), Mouse Cav1 (protein-coding), Rat Cav1 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr7:116164839..116201239 (36.40 kb) View in Genome Browser

(Mouse) NCBIM37 - chr6:17256335..17291452 (35.12 kb) View in Genome Browser

(Rat) RGSC3.4 - chr4:42956102..42989057 (32.95 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for CAV1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for CAV1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 4

Biocarta: 2

Reactome: 7

NCI-Nature Pathway Interaction Database: 10

Gene Ontology: 109

Negative regulation of transcription from RNA polymerase II promoter	GO:0000122
Golgi membrane	GO:0000139
Inactivation of MAPK activity	GO:0000188
Integral to membrane of membrane fraction	GO:0000299
Vasculogenesis	GO:0001570
Response to hypoxia	GO:0001666
Negative regulation of endothelial cell proliferation	GO:0001937
Negative regulation of cytokine-mediated signaling pathway	GO:0001960
Acrosomal membrane	GO:0002080
Receptor binding	GO:0005102
Patched binding	GO:0005113
Structural molecule activity	GO:0005198
Protein binding	GO:0005515
Intracellular	GO:0005622
Soluble fraction	GO:0005625
Cytoplasm	GO:0005737
Mitochondrion	GO:0005739
Endosome	GO:0005768
Endoplasmic reticulum	GO:0005783
Golgi apparatus	GO:0005794
Lipid particle	GO:0005811
Cytosol	GO:0005829
Plasma membrane	GO:0005886
Integral to plasma membrane	GO:0005887
Caveola	GO:0005901
Focal adhesion	GO:0005925
Cell cortex	GO:0005938
Triglyceride metabolic process	GO:0006641
Calcium ion transport	GO:0006816
Cellular calcium ion homeostasis	GO:0006874
Regulation of smooth muscle contraction	GO:0006940
Skeletal muscle tissue development	GO:0007519
Response to nutrient	GO:0007584
Lactation	GO:0007595
Blood coagulation	GO:0007596
Protein localization	GO:0008104
Negative regulation of cell proliferation	GO:0008285
Induction of apoptosis by extracellular signals	GO:0008624
Cellular response to starvation	GO:0009267
Response to mechanical stimulus	GO:0009612
Basal plasma membrane	GO:0009925
Positive regulation of signal transduction	GO:0009967
Cell surface	GO:0009986
Response to gamma radiation	GO:0010332
Positive regulation of calcium ion transport into cytosol	GO:0010524
Positive regulation of peptidase activity	GO:0010952
Cholesterol binding	GO:0015485
Vesicle organization	GO:0016050
Basolateral plasma membrane	GO:0016323
Apical plasma membrane	GO:0016324
Peptidase activator activity	GO:0016504
Regulation of fatty acid metabolic process	GO:0019217
Flagellum	GO:0019861
Kinase binding	GO:0019900
Syntaxin binding	GO:0019905
Lipid storage	GO:0019915
Regulation of blood coagulation	GO:0030193
Cholesterol transport	GO:0030301
Negative regulation of BMP signaling pathway	GO:0030514
Endocytic vesicle membrane	GO:0030666
Negative regulation of epithelial cell differentiation	GO:0030857
Mammary gland development	GO:0030879
Positive regulation of microtubule polymerization	GO:0031116
T cell costimulation	GO:0031295
Cytoplasmic vesicle	GO:0031410
Negative regulation of protein binding	GO:0032091
Maintenance of protein location in cell	GO:0032507
Response to progesterone stimulus	GO:0032570
Protein complex scaffold	GO:0032947
Negative regulation of peptidyl-serine phosphorylation	GO:0033137
Positive regulation of peptidyl-serine phosphorylation	GO:0033138
Cholesterol efflux	GO:0033344
Nitric oxide homeostasis	GO:0033484
Response to drug	GO:0042493
Negative regulation of tyrosine phosphorylation of Stat5 protein	GO:0042524
Cholesterol homeostasis	GO:0042632
Protein complex	GO:0043234
Negative regulation of MAPK cascade	GO:0043409
Response to estrogen stimulus	GO:0043627
Small molecule metabolic process	GO:0044281
Interspecies interaction between organisms	GO:0044419
Negative regulation of nitric oxide biosynthetic process	GO:0045019
Membrane raft	GO:0045121
Positive regulation of anti-apoptosis	GO:0045768
Positive regulation of endocytosis	GO:0045807
Positive regulation of vasoconstriction	GO:0045907
Nitric oxide metabolic process	GO:0046209
Negative regulation of JAK-STAT cascade	GO:0046426
Perinuclear region of cytoplasm	GO:0048471
Positive regulation of metalloenzyme activity	GO:0048554
Leukocyte migration	GO:0050900
Nitric-oxide synthase binding	GO:0050998
Regulation of nitric-oxide synthase activity	GO:0050999
Protein homooligomerization	GO:0051260
Response to glucocorticoid stimulus	GO:0051384
Cytosolic calcium ion homeostasis	GO:0051480
Response to calcium ion	GO:0051592
Membrane depolarization	GO:0051899
Regulation of peptidase activity	GO:0052547
Calcium ion homeostasis	GO:0055074
Mammary gland involution	GO:0060056
Caveola assembly	GO:0070836
Cellular response to hyperoxia	GO:0071455
Caveolin-mediated endocytosis	GO:0072584
Negative regulation of canonical Wnt receptor signaling pathway	GO:0090090
Positive regulation of canonical Wnt receptor signaling pathway	GO:0090263
Receptor internalization involved in canonical Wnt receptor signaling pathway	GO:2000286
Positive regulation of extrinsic apoptotic signaling pathway	GO:2001238
Positive regulation of intrinsic apoptotic signaling pathway	GO:2001244

Publications from PubMed Top Help

Type 1 Diabetes Publications: 7

Publications: 909

Alveolar epithelial type II cells and their microenvironment in the caveolin-1-deficient mouse.
Jung K, Schlenz H, Krasteva G, Mühlfeld C
Anat Rec (Hoboken). 2012
PubMed ID: 22213628
Diet-induced obesity increases melanoma progression: involvement of Cav-1 and FASN.
Pandey V, Vijayakumar MV, Ajay AK, Malvi P, Bhat MK
Int J Cancer. 2012
PubMed ID: 21387314
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.
Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonnière L, Bernard M, van Horssen J, de Vries HE, Charron F, Prat A
Science. 2011
PubMed ID: 22144466
Caveolin-1 is a negative regulator of MMP-1 gene expression in human dermal fibroblasts via inhibition of Erk1/2/Ets1 signaling pathway.
Haines P, Samuel GH, Cohen H, Trojanowska M, Bujor AM
J Dermatol Sci. 2011
PubMed ID: 21925842
Role of caveolin-1 in endothelial BKCa channel regulation of vasoreactivity.
Riddle MA, Hughes JM, Walker BR
Am J Physiol Cell Physiol. 2011
PubMed ID: 21900688
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA.
Wiggs JL, Kang JH, Yaspan BL, Mirel DB, Laurie C, Crenshaw A, Brodeur W, Gogarten S, Olson LM, Abdrabou W, DelBono E, Loomis S, Haines JL, Pasquale LR, GENEVA Consortium
Hum Mol Genet. 2011
PubMed ID: 21873608
Caveolin-1 sensitizes cisplatin-induced lung cancer cell apoptosis via superoxide anion-dependent mechanism.
Pongjit K, Chanvorachote P
Mol Cell Biochem. 2011
PubMed ID: 21761200
A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells.
Prinetti A, Cao T, Illuzzi G, Prioni S, Aureli M, Gagliano N, Tredici G, Rodriguez-Menendez V, Chigorno V, Sonnino S
J Biol Chem. 2011
PubMed ID: 21949119
PPARα and PPARγ protect against HIV-1-induced MMP-9 overexpression via caveolae-associated ERK and Akt signaling.
Huang W, András IE, Rha GB, Hennig B, Toborek M
FASEB J. 2011
PubMed ID: 21840940
Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response.
Engel D, Beckers L, Wijnands E, Seijkens T, Lievens D, Drechsler M, Gerdes N, Soehnlein O, Daemen MJ, Stan RV, Biessen EA, Lutgens E
FASEB J. 2011
PubMed ID: 21795505
Interaction abolishment between mutant caveolin-1(Δ62-100) and ABCA1 reduces HDL-mediated cellular cholesterol efflux.
Kuo CY, Lin YC, Yang JJ, Yang VC
Biochem Biophys Res Commun. 2011
PubMed ID: 21951852
Association of caveolin-1 genotypes with nasopharyngeal carcinoma susceptibility in Taiwan.
Tsou YA, Tsai CW, Tsai MH, Chang WS, Li FJ, Liu YF, Chiu CF, Lin CC, Bau DT
Anticancer Res. 2011
PubMed ID: 21965789
Significant association of caveolin-1 (CAV1) genotypes with breast cancer in Taiwan.
Liu LC, Su CH, Wang HC, Tsai CW, Chang WS, Ho CY, Wu CI, Li FJ, Lin CH, Lane HY, Bau DT
Anticancer Res. 2011
PubMed ID: 21965771
Caveolin-1 in cytokine-induced enhancement of intracellular Ca(2+) in human airway smooth muscle.
Sathish V, Abcejo AJ, VanOosten SK, Thompson MA, Prakash YS, Pabelick CM
Am J Physiol Lung Cell Mol Physiol. 2011
PubMed ID: 21803870
Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.
Place AT, Chen Z, Bakhshi FR, Liu G, O'Bryan JP, Minshall RD
Mol Pharmacol. 2011
PubMed ID: 21778303
Differential impact of caveolae and caveolin-1 scaffolds on the membrane raft proteome.
Zheng YZ, Boscher C, Inder KL, Fairbank M, Loo D, Hill MM, Nabi IR, Foster LJ
Mol Cell Proteomics. 2011
PubMed ID: 21753190
Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1.
Wang P, Zhu F, Tong Z, Konstantopoulos K
FASEB J. 2011
PubMed ID: 21715681
Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons.
Head BP, Hu Y, Finley JC, Saldana MD, Bonds JA, Miyanohara A, Niesman IR, Ali SS, Murray F, Insel PA, Roth DM, Patel HH, Patel PM
J Biol Chem. 2011
PubMed ID: 21799010
Caveolin-1 orchestrates TCR synaptic polarity, signal specificity, and function in CD8 T cells.
Tomassian T, Humphries LA, Liu SD, Silva O, Brooks DG, Miceli MC
J Immunol. 2011
PubMed ID: 21849673
Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations.
Ritz D, Vuk M, Kirchner P, Bug M, Schütz S, Hayer A, Bremer S, Lusk C, Baloh RH, Lee H, Glatter T, Gstaiger M, Aebersold R, Weihl CC, Meyer H
Nat Cell Biol. 2011
PubMed ID: 21822278
A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice.
Bernatchez P, Sharma A, Bauer PM, Marin E, Sessa WC
J Clin Invest. 2011
PubMed ID: 21804187
Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells.
Lobysheva I, Rath G, Sekkali B, Bouzin C, Feron O, Gallez B, Dessy C, Balligand JL
Arterioscler Thromb Vasc Biol. 2011
PubMed ID: 21659644
Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate.
Bryant KG, Camacho J, Jasmin JF, Wang C, Addya S, Casimiro MC, Fortina P, Balasubramaniam S, Knudsen KE, Schwarting R, Lisanti MP, Mercier I
Int J Biochem Cell Biol. 2011
PubMed ID: 21601007
Caveolin-1 is a competitive inhibitor of heme oxygenase-1 (HO-1) with heme: identification of a minimum sequence in caveolin-1 for binding to HO-1.
Taira J, Sugishima M, Kida Y, Oda E, Noguchi M, Higashimoto Y
Biochemistry. 2011
PubMed ID: 21721581
Recruitment of α7 nicotinic acetylcholine receptor to caveolin-1-enriched lipid rafts is required for nicotine-enhanced Escherichia coli K1 entry into brain endothelial cells.
Chi F, Wang L, Zheng X, Jong A, Huang SH
Future Microbiol. 2011
PubMed ID: 21861625
The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain.
Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, Röcken C, Perren A, Wright MB, Schmid RM, Seger R, Ebert MP
Mol Cell Biol. 2011
PubMed ID: 21690289
Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension.
Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH
J Clin Endocrinol Metab. 2011
PubMed ID: 21613355
Prognostic significance of tumor/stromal caveolin-1 expression in breast cancer patients.
Qian N, Ueno T, Kawaguchi-Sakita N, Kawashima M, Yoshida N, Mikami Y, Wakasa T, Shintaku M, Tsuyuki S, Inamoto T, Toi M
Cancer Sci. 2011
PubMed ID: 21585620
The impact of caveolin protein expression in tumor stroma on prognosis of breast cancer.
Koo JS, Park S, Kim SI, Lee S, Park BW
Tumour Biol. 2011
PubMed ID: 21584795
Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells.
Zhang L, Wang Y, Wang L, Cao T, Hyuga S, Sato T, Wu Y, Yamagata S, Yamagata T
Biochim Biophys Acta. 2011
PubMed ID: 21554929
Leptin upregulates caveolin-1 expression: implications for development of atherosclerosis.
Singh P, Peterson TE, Sert-Kuniyoshi FH, Jensen MD, Somers VK
Atherosclerosis. 2011
PubMed ID: 21074769
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis.
Goetz JG, Minguet S, Navarro-Lérida I, Lazcano JJ, Samaniego R, Calvo E, Tello M, Osteso-Ibáñez T, Pellinen T, Echarri A, Cerezo A, Klein-Szanto AJ, Garcia R, Keely PJ, Sánchez-Mateos P, Cukierman E, Del Pozo MA
Cell. 2011
PubMed ID: 21729786
The human caveolin 1 gene upstream purine complex and neurodegeneration--a common signature.
Heidari A, Behmanesh M, Sahraian MA, Meshkani R, Darvish H, Najmabadi H, Ohadi M
J Neuroimmunol. 2011
PubMed ID: 21683457
Caveolin-1 and integrin β1 regulate embryonic stem cell proliferation via p38 MAPK and FAK in high glucose.
Lee SH, Lee YJ, Park SW, Kim HS, Han HJ
J Cell Physiol. 2011
PubMed ID: 21506116
Significant association of caveolin-1 genotypes with bladder cancer susceptibility in Taiwan.
Bau DT, Chang CH, Tsai RY, Wang HC, Wang RF, Tsai CW, Yao CH, Chen YS, Shyue SK, Huang CY
Chin J Physiol. 2011
PubMed ID: 21789897
Elevated inflammatory response in caveolin-1-deficient mice with Pseudomonas aeruginosa infection is mediated by STAT3 protein and nuclear factor kappaB (NF-kappaB).
Yuan K, Huang C, Fox J, Gaid M, Weaver A, Li G, Singh BB, Gao H, Wu M
J Biol Chem. 2011
PubMed ID: 21515682
Caveolin-1 modulates TGF-β1 signaling in cardiac remodeling.
Miyasato SK, Loeffler J, Shohet R, Zhang J, Lindsey M, Le Saux CJ
Matrix Biol. 2011
PubMed ID: 21641995
Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration.
Popescu LM, Manole E, Serboiu CS, Manole CG, Suciu LC, Gherghiceanu M, Popescu BO
J Cell Mol Med. 2011
PubMed ID: 21609392
Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.
Martinez-Outschoorn UE, Whitaker-Menezes D, Lin Z, Flomenberg N, Howell A, Pestell RG, Lisanti MP, Sotgia F
Cell Cycle. 2011
PubMed ID: 21566463
NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53.
Wilson KA, Colavito SA, Schulz V, Wakefield PH, Sessa W, Tuck D, Stern DF
Mol Cancer Res. 2011
PubMed ID: 21551225
Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers.
Witkiewicz AK, Kline J, Queenan M, Brody JR, Tsirigos A, Bilal E, Pavlides S, Ertel A, Sotgia F, Lisanti MP
Cell Cycle. 2011
PubMed ID: 21521946
Uterine cysts in female mice deficient for caveolin-1 and insulin-like 3 receptor RXFP2.
Li Z, Feng S, Lopez V, Elhammady G, Anderson ML, Kaftanovskaya EM, Agoulnik AI
Endocrinology. 2011
PubMed ID: 21467199
Caveolin 1 inhibits HIV replication by transcriptional repression mediated through NF-κB.
Wang XM, Nadeau PE, Lin S, Abbott JR, Mergia A
J Virol. 2011
PubMed ID: 21430048
Real-time dynamic movement of caveolin-1 during smooth muscle contraction of human colon and aged rat colon transfected with caveolin-1 cDNA.
Somara S, Bashllari D, Gilmont RR, Bitar KN
Am J Physiol Gastrointest Liver Physiol. 2011
PubMed ID: 21372166
Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.
Siddiqui MR, Komarova YA, Vogel SM, Gao X, Bonini MG, Rajasingh J, Zhao YY, Brovkovych V, Malik AB
J Cell Biol. 2011
PubMed ID: 21624953
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis.
Zhang M, Lee SJ, An C, Xu JF, Joshi B, Nabi IR, Choi AM, Jin Y
Free Radic Biol Med. 2011
PubMed ID: 21382479
Transcriptional repression of Caveolin-1 (CAV1) gene expression by GATA-6 in bladder smooth muscle hypertrophy in mice and human beings.
Boopathi E, Gomes CM, Goldfarb R, John M, Srinivasan VG, Alanzi J, Malkowicz SB, Kathuria H, Zderic SA, Wein AJ, Chacko S
Am J Pathol. 2011
PubMed ID: 21514437
Caveolin 1 inhibits transforming growth factor-β1 activity via inhibition of Smad signaling by hypertrophic scar derived fibroblasts in vitro.
Zhang GY, He B, Liao T, Luan Q, Tao C, Nie CL, Albers AE, Zheng X, Xie XG, Gao WY
J Dermatol Sci. 2011
PubMed ID: 21440420
Auto-stimulatory action of secreted caveolin-1 on the proliferation of Ewing's sarcoma cells.
Sengupta A, Mateo-Lozano S, Tirado OM, Notario V
Int J Oncol. 2011
PubMed ID: 21373757
The association of Caveolin-1 genotypes with oral cancer susceptibility in Taiwan.
Bau DT, Tsai MH, Tsou YA, Wang CH, Tsai CW, Sun SS, Hua CH, Shyue SK, Tsai RY
Ann Surg Oncol. 2011
PubMed ID: 21246406
Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.
Bosch M, Marí M, Herms A, Fernández A, Fajardo A, Kassan A, Giralt A, Colell A, Balgoma D, Barbero E, González-Moreno E, Matias N, Tebar F, Balsinde J, Camps M, Enrich C, Gross SP, García-Ruiz C, Pérez-Navarro E, Fernández-Checa JC, Pol A
Curr Biol. 2011
PubMed ID: 21497090
Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions.
Li Y, Lau WM, So KF, Tong Y, Shen J
Biochem Biophys Res Commun. 2011
PubMed ID: 21414292
Caveolin 1 mRNA is overexpressed in malignant renal tissue and might serve as a novel diagnostic marker for renal cancer.
Waalkes S, Eggers H, Blasig H, Atschekzei F, Kramer MW, Hennenlotter J, Tränkenschuh W, Stenzl A, Serth J, Schrader AJ, Kuczyk MA, Merseburger AS
Biomark Med. 2011
PubMed ID: 21473727
Caveolin-1 in sarcomas: friend or foe?
Sáinz-Jaspeado M, Martin-Liberal J, Lagares-Tena L, Mateo-Lozano S, Garcia del Muro X, Tirado OM
Oncotarget. 2011
PubMed ID: 21471610
Caveolin-1 deletion reduces early brain injury after experimental intracerebral hemorrhage.
Chang CF, Chen SF, Lee TS, Lee HF, Chen SF, Shyue SK
Am J Pathol. 2011
PubMed ID: 21435456
Caveolin-1 deficiency exacerbates cardiac dysfunction and reduces survival in mice with myocardial infarction.
Jasmin JF, Rengo G, Lymperopoulos A, Gupta R, Eaton GJ, Quann K, Gonzales DM, Mercier I, Koch WJ, Lisanti MP
Am J Physiol Heart Circ Physiol. 2011
PubMed ID: 21297026
Decreased caveolin-1 levels contribute to fibrosis and deposition of extracellular IGFBP-5.
Yamaguchi Y, Yasuoka H, Stolz DB, Feghali-Bostwick CA
J Cell Mol Med. 2011
PubMed ID: 20345844
Eph-B4 prevents venous adaptive remodeling in the adult arterial environment.
Muto A, Yi T, Harrison KD, Dávalos A, Fancher TT, Ziegler KR, Feigel A, Kondo Y, Nishibe T, Sessa WC, Dardik A
J Exp Med. 2011
PubMed ID: 21339325
Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
Jin C, Shelburne CP, Li G, Potts EN, Riebe KJ, Sempowski GD, Foster WM, Abraham SN
J Clin Invest. 2011
PubMed ID: 21285515
Caveolin-1 negatively regulates a metalloprotease-dependent epidermal growth factor receptor transactivation by angiotensin II.
Takaguri A, Shirai H, Kimura K, Hinoki A, Eguchi K, Carlile-Klusacek M, Yang B, Rizzo V, Eguchi S
J Mol Cell Cardiol. 2011
PubMed ID: 21172357
Endogenous adipocyte apolipoprotein E is colocalized with caveolin at the adipocyte plasma membrane.
Yue L, Mazzone T
J Lipid Res. 2011
PubMed ID: 21169230
Biomechanical properties and innervation of the female caveolin-1-deficient detrusor.
Sadegh MK, Ekman M, Rippe C, Sundler F, Wierup N, Mori M, Uvelius B, Swärd K
Br J Pharmacol. 2011
PubMed ID: 21091642
Caveolin-1 assembles type 1 inositol 1,4,5-trisphosphate receptors and canonical transient receptor potential 3 channels into a functional signaling complex in arterial smooth muscle cells.
Adebiyi A, Narayanan D, Jaggar JH
J Biol Chem. 2011
PubMed ID: 21098487
Significant association of caveolin-1 (CAV1) genotypes with prostate cancer susceptibility in Taiwan.
Wu HC, Chang CH, Tsou YA, Tsai CW, Lin CC, Bau DT
Anticancer Res. 2011
PubMed ID: 21378366
Distinct roles of endothelial and adipocyte caveolin-1 in macrophage infiltration and adipose tissue metabolic activity.
Briand N, Le Lay S, Sessa WC, Ferré P, Dugail I
Diabetes. 2011
PubMed ID: 21270257
Differential expression and function of the caveolin-1 gene in non-small cell lung carcinoma.
Chen HL, Fan LF, Gao J, Ouyang JP, Zhang YX
Oncol Rep. 2011
PubMed ID: 21165568
Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation.
Rungtabnapa P, Nimmannit U, Halim H, Rojanasakul Y, Chanvorachote P
Am J Physiol Cell Physiol. 2011
PubMed ID: 21148404
p190 RhoGTPase-activating protein links the β1 integrin/caveolin-1 mechanosignaling complex to RhoA and actin remodeling.
Yang B, Radel C, Hughes D, Kelemen S, Rizzo V
Arterioscler Thromb Vasc Biol. 2011
PubMed ID: 21051664
RNA inference-mediated caveolin-1 down-regulation decrease estrogen receptor alpha (ERα) signaling in human mammary epithelial cells.
Wang X, Feng S, Zhang H, Wang Y, Cui Y, Wang Z, Liu J, Zou W
Mol Biol Rep. 2011
PubMed ID: 20411337
Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome.
Pei L, Leblanc M, Barish G, Atkins A, Nofsinger R, Whyte J, Gold D, He M, Kawamura K, Li HR, Downes M, Yu RT, Powell HC, Lingrel JB, Evans RM
Nat Med. 2011
PubMed ID: 22001906
Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux.
Le Lay S, Rodriguez M, Jessup W, Rentero C, Li Q, Cartland S, Grewal T, Gaus K
PLoS One. 2011
PubMed ID: 21858084
Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway.
Li Y, Luo J, Lau WM, Zheng G, Fu S, Wang TT, Zeng HP, So KF, Chung SK, Tong Y, Liu K, Shen J
PLoS One. 2011
PubMed ID: 21826216
Caveolin-1, caveolin-3 and VEGF expression in the masticatory muscles of mdx mice.
Kunert-Keil C, Gredes T, Lucke S, Morgenstern S, Mielczarek A, Sporniak-Tutak K, Gedrange T, Spassov A
Folia Histochem Cytobiol. 2011
PubMed ID: 21744331
IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis.
Martins AS, Ordóñez JL, Amaral AT, Prins F, Floris G, Debiec-Rychter M, Hogendoorn PC, de Alava E
PLoS One. 2011
PubMed ID: 21611203
Caveolin-1 may participate in the pathogenesis of bladder pain syndrome/ interstitial cystitis.
Lin XC, Zhang QH, Zhou P, Zhou ZS, Lu GS
Urol Int. 2011
PubMed ID: 21335944
Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort.
Kuehn MH, Wang K, Roos B, Stone EM, Kwon YH, Alward WL, Mullins RF, Fingert JH
Mol Vis. 2011
PubMed ID: 21321670
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma.
Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
Int J Oncol. 2011
PubMed ID: 21109942
Caveolin-1 is required for vascular endothelial insulin uptake.
Wang H, Wang AX, Barrett EJ
Am J Physiol Endocrinol Metab. 2011
PubMed ID: 20959538
Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase.
Borza CM, Chen X, Mathew S, Mont S, Sanders CR, Zent R, Pozzi A
J Biol Chem. 2010
PubMed ID: 20940300
Role for vitamin D receptor in the neuronal control of the hematopoietic stem cell niche.
Kawamori Y, Katayama Y, Asada N, Minagawa K, Sato M, Okamura A, Shimoyama M, Nakagawa K, Okano T, Tanimoto M, Kato S, Matsui T
Blood. 2010
PubMed ID: 20813899
Caveolin limits membrane microdomain mobility and integrin-mediated uptake of fibronectin-binding pathogens.
Hoffmann C, Berking A, Agerer F, Buntru A, Neske F, Chhatwal GS, Ohlsen K, Hauck CR
J Cell Sci. 2010
PubMed ID: 21098633
Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1.
Luanpitpong S, Talbott SJ, Rojanasakul Y, Nimmannit U, Pongrakhananon V, Wang L, Chanvorachote P
J Biol Chem. 2010
PubMed ID: 20923773
Static pressure accelerates ox-LDL-induced cholesterol accumulation via SREBP-1-mediated caveolin-1 downregulation in cultured vascular smooth muscle cells.
Luo DX, Xia CL, Li JM, Xiong Y, Yuan HY, Tang ZW, Zeng Y, Liao DF
Biochem Biophys Res Commun. 2010
PubMed ID: 21036148
Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.
Peloso GM, Demissie S, Collins D, Mirel DB, Gabriel SB, Cupples LA, Robins SJ, Schaefer EJ, Brousseau ME
J Lipid Res. 2010
PubMed ID: 20855565
MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.
Zhang X, Yang H, Lee JJ, Kim E, Lippman SM, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X
Carcinogenesis. 2010
PubMed ID: 20819778
Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency.
Beauchesne E, Desjardins P, Butterworth RF, Hazell AS
Neurochem Int. 2010
PubMed ID: 20816907
Caveolin-1 inhibits TrkA-induced cell death by influencing on TrkA modification associated with tyrosine-490 phosphorylation.
Jung EJ, Kim CW
Biochem Biophys Res Commun. 2010
PubMed ID: 20977883
Caveolin-1 knockout mice exhibit impaired induction of mGluR-dependent long-term depression at CA3-CA1 synapses.
Takayasu Y, Takeuchi K, Kumari R, Bennett MV, Zukin RS, Francesconi A
Proc Natl Acad Sci U S A. 2010
PubMed ID: 21098662
Regulator of G-protein signaling 14 protein modulates Ca²+ influx through Cav1 channels.
Martín-Montañez E, Acevedo MJ, López-Téllez JF, Duncan RS, Mateos AG, Pavía J, Koulen P, Khan ZU
Neuroreport. 2010
PubMed ID: 20842066
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema.
Chen ZH, Lam HC, Jin Y, Kim HP, Cao J, Lee SJ, Ifedigbo E, Parameswaran H, Ryter SW, Choi AM
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20956295
Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize.
Sáinz-Jaspeado M, Lagares-Tena L, Lasheras J, Navid F, Rodriguez-Galindo C, Mateo-Lozano S, Notario V, Sanjuan X, Garcia Del Muro X, Fabra A, Tirado OM
Mol Cancer Res. 2010
PubMed ID: 21106507
Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation.
Hayer A, Stoeber M, Ritz D, Engel S, Meyer HH, Helenius A
J Cell Biol. 2010
PubMed ID: 21041450
High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness.
Singleton PA, Mirzapoiazova T, Guo Y, Sammani S, Mambetsariev N, Lennon FE, Moreno-Vinasco L, Garcia JG
Am J Physiol Lung Cell Mol Physiol. 2010
PubMed ID: 20709728
Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice.
Krieger MH, Di Lorenzo A, Teutsch C, Kauser K, Sessa WC
Lab Invest. 2010
PubMed ID: 20585312
Effects of green tea polyphenols on caveolin-1 of microvessel fragments in rats with cerebral ischemia.
Zhang S, Liu Y, Zhao Z, Xue Y
Neurol Res. 2010
PubMed ID: 20444327
The role of proline in the membrane re-entrant helix of caveolin-1.
Aoki S, Thomas A, Decaffmeyer M, Brasseur R, Epand RM
J Biol Chem. 2010
PubMed ID: 20729193
Global gene expression profiling and tissue microarray reveal novel candidate genes and down-regulation of the tumor suppressor gene CAV1 in sporadic vestibular schwannomas.
Aarhus M, Bruland O, Sætran HA, Mork SJ, Lund-Johansen M, Knappskog PM
Neurosurgery. 2010
PubMed ID: 20881564
Caveolae and caveolin-1 mediate endocytosis and transcytosis of oxidized low density lipoprotein in endothelial cells.
Sun SW, Zu XY, Tuo QH, Chen LX, Lei XY, Li K, Tang CK, Liao DF
Acta Pharmacol Sin. 2010
PubMed ID: 20835266
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.
Thorleifsson G, Walters GB, Hewitt AW, Masson G, Helgason A, DeWan A, Sigurdsson A, Jonasdottir A, Gudjonsson SA, Magnusson KP, Stefansson H, Lam DS, Tam PO, Gudmundsdottir GJ, Southgate L, Burdon KP, Gottfredsdottir MS, Aldred MA, Mitchell P, St Clair D, Collier DA, Tang N, Sveinsson O, Macgregor S, Martin NG, Cree AJ, Gibson J, Macleod A, Jacob A, Ennis S, Young TL, Chan JC, Karwatowski WS, Hammond CJ, Thordarson K, Zhang M, Wadelius C, Lotery AJ, Trembath RC, Pang CP, Hoh J, Craig JE, Kong A, Mackey DA, Jonasson F, Thorsteinsdottir U, Stefansson K
Nat Genet. 2010
PubMed ID: 20835238
Cardiac function is not significantly diminished in hearts isolated from young caveolin-1 knockout mice.
Chow AK, Daniel EE, Schulz R
Am J Physiol Heart Circ Physiol. 2010
PubMed ID: 20693397
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
[Expression of Cav-1, AQP1 and AQP5 in lung of acute pancreatitis-associated lung injury rats and the therapeutic role of Qingyitang].
WANG G, CHEN HL, REN F, LI J, LI YQ
Zhonghua Yi Xue Za Zhi. 2010
PubMed ID: 21092464
beta-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release.
Sharma P, Ghavami S, Stelmack GL, McNeill KD, Mutawe MM, Klonisch T, Unruh H, Halayko AJ
J Cell Sci. 2010
PubMed ID: 20736308
Caveolin-1 and VEGF-C promote lymph node metastasis in the absence of intratumoral lymphangiogenesis in non-small cell lung cancer.
Li M, Chen H, Diao L, Zhang Y, Xia C, Yang F
Tumori. 2010
PubMed ID: 21302621
Silencing vascular smooth muscle ATP-sensitive K+ channels with caveolin-1.
Cole WC
J Physiol. 2010
PubMed ID: 20810358
Interaction with caveolin-1 modulates vascular ATP-sensitive potassium (KATP) channel activity.
Davies LM, Purves GI, Barrett-Jolley R, Dart C
J Physiol. 2010
PubMed ID: 20624795
HIV infection upregulates caveolin 1 expression to restrict virus production.
Lin S, Wang XM, Nadeau PE, Mergia A
J Virol. 2010
PubMed ID: 20610713
Absence of the caveolin-1 P132L mutation in cancers of the breast and other organs.
Koike S, Kodera Y, Nakao A, Iwata H, Yatabe Y
J Mol Diagn. 2010
PubMed ID: 20581046
Caveolin-1-ablated mice survive in cold by nonshivering thermogenesis despite desensitized adrenergic responsiveness.
Mattsson CL, Csikasz RI, Shabalina IG, Nedergaard J, Cannon B
Am J Physiol Endocrinol Metab. 2010
PubMed ID: 20530737
Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblasts.
Quintas LE, Pierre SV, Liu L, Bai Y, Liu X, Xie ZJ
J Mol Cell Cardiol. 2010
PubMed ID: 20451529
Reduced expression of angiotensin I-converting enzyme in caveolin-1 knockout mouse lungs.
Maniatis NA, Balyasnikova IV, Metzger R, Castellon M, Visintine DJ, Schwartz DE, Minshall RD, Danilov SM
Microvasc Res. 2010
PubMed ID: 20430040
Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
Feher A, Rutkai I, Beleznai T, Ungvari Z, Csiszar A, Edes I, Bagi Z
Cardiovasc Res. 2010
PubMed ID: 20299334
Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels.
Massaeli H, Sun T, Li X, Shallow H, Wu J, Xu J, Li W, Hanson C, Guo J, Zhang S
J Biol Chem. 2010
PubMed ID: 20605793
The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes.
Le Lay S, Briand N, Blouin CM, Chateau D, Prado C, Lasnier F, Le Liepvre X, Hajduch E, Dugail I
Autophagy. 2010
PubMed ID: 20574167
Caveolin-1 protects against sepsis by modulating inflammatory response, alleviating bacterial burden, and suppressing thymocyte apoptosis.
Feng H, Guo L, Song Z, Gao H, Wang D, Fu W, Han J, Li Z, Huang B, Li XA
J Biol Chem. 2010
PubMed ID: 20534584
SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells.
Truong TQ, Aubin D, Falstrault L, Brodeur MR, Brissette L
Cell Biochem Funct. 2010
PubMed ID: 20629037
Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice.
Fernández-Hernando C, Yu J, Dávalos A, Prendergast J, Sessa WC
Am J Pathol. 2010
PubMed ID: 20581061
Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract.
Uemura T, Stringer DE, Blohm-Mangone KA, Gerner EW
Am J Physiol Gastrointest Liver Physiol. 2010
PubMed ID: 20522643
MMTV promoter-regulated caveolin-1 overexpression yields defective parenchymal epithelia in multiple exocrine organs of transgenic mice.
Yang G, Park S, Cao G, Goltsov A, Ren C, Truong LD, Demayo F, Thompson TC
Exp Mol Pathol. 2010
PubMed ID: 20399205
Differential involvement of caveolin-1 in brown adipocyte signaling: impaired beta3-adrenergic, but unaffected LPA, PDGF and EGF receptor signaling.
Mattsson CL, Andersson ER, Nedergaard J
Biochim Biophys Acta. 2010
PubMed ID: 20381543
Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery.
Wittrup A, Zhang SH, Svensson KJ, Kucharzewska P, Johansson MC, Mörgelin M, Belting M
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20624969
Increased P2X7R expression in atrial cardiomyocytes of caveolin-1 deficient mice.
Barth K, Pfleger C, Linge A, Sim JA, Surprenant A, Steinbronn N, Strasser RH, Kasper M
Histochem Cell Biol. 2010
PubMed ID: 20563595
Caveolin-1 induces formation of membrane tubules that sense actomyosin tension and are inhibited by polymerase I and transcript release factor/cavin-1.
Verma P, Ostermeyer-Fay AG, Brown DA
Mol Biol Cell. 2010
PubMed ID: 20427576
Polychlorinated biphenyl-induced VCAM-1 expression is attenuated in aortic endothelial cells isolated from caveolin-1 deficient mice.
Han SG, Eum SY, Toborek M, Smart E, Hennig B
Toxicol Appl Pharmacol. 2010
PubMed ID: 20406653
Caveolin-1 modulates HIV-1 envelope-induced bystander apoptosis through gp41.
Wang XM, Nadeau PE, Lo YT, Mergia A
J Virol. 2010
PubMed ID: 20392844
Caveolae and caveolin-1 are implicated in 1alpha,25(OH)2-vitamin D3-dependent modulation of Src, MAPK cascades and VDR localization in skeletal muscle cells.
Buitrago C, Boland R
J Steroid Biochem Mol Biol. 2010
PubMed ID: 20211253
Over-expression of caveolin-1 aggravate LPS-induced inflammatory response in AT-1 cells via up-regulation of cPLA2/p38 MAPK.
Lv XJ, Li YY, Zhang YJ, Mao M, Qian GS
Inflamm Res. 2010
PubMed ID: 20099006
Knocking down Cav1 calcium channels implicated in Th2 cell activation prevents experimental asthma.
Cabral MD, Paulet PE, Robert V, Gomes B, Renoud ML, Savignac M, Leclerc C, Moreau M, Lair D, Langelot M, Magnan A, Yssel H, Mariamé B, Guéry JC, Pelletier L
Am J Respir Crit Care Med. 2010
PubMed ID: 20167851
Caveolin-1 mutants P132L and Y14F are dominant negative regulators of invasion, migration and aggregation in H1299 lung cancer cells.
Shatz M, Lustig G, Reich R, Liscovitch M
Exp Cell Res. 2010
PubMed ID: 20153318
[Analysis of the relationship between expression of caveolin-1 and prognosis in bladder transitional cell carcinoma].
Ruan J, Weng ZL
Zhonghua Zhong Liu Za Zhi. 2010
PubMed ID: 20819483
[Mechanisms of foam cell formation in smooth muscle cell derived from bone marrow stem cells].
Yan PK, Li SH, Duang CW, Mei ZR, Tan XP, Si TB, Xiao GH
Nan Fang Yi Ke Da Xue Xue Bao. 2010
PubMed ID: 20584649
Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation.
Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Fortina P, Addya S, Pestell RG, Martinez-Outschoorn UE, Sotgia F, Lisanti MP
Cell Cycle. 2010
PubMed ID: 20519932
Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway.
Nethe M, Anthony EC, Fernandez-Borja M, Dee R, Geerts D, Hensbergen PJ, Deelder AM, Schmidt G, Hordijk PL
J Cell Sci. 2010
PubMed ID: 20460433
Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis.
Xia H, Khalil W, Kahm J, Jessurun J, Kleidon J, Henke CA
Am J Pathol. 2010
PubMed ID: 20395445
Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression.
Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A
Mol Cell Biol. 2010
PubMed ID: 20368353
Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice.
Pojoga LH, Adamová Z, Kumar A, Stennett AK, Romero JR, Adler GK, Williams GH, Khalil RA
Am J Physiol Heart Circ Physiol. 2010
PubMed ID: 20363891
A role for caveolin-1 in mechanotransduction of fetal type II epithelial cells.
Wang Y, Maciejewski BS, Drouillard D, Santos M, Hokenson MA, Hawwa RL, Huang Z, Sanchez-Esteban J
Am J Physiol Lung Cell Mol Physiol. 2010
PubMed ID: 20172952
Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation.
Mirza MK, Yuan J, Gao XP, Garrean S, Brovkovych V, Malik AB, Tiruppathi C, Zhao YY
Am J Pathol. 2010
PubMed ID: 20304961
Caveolin-1 is enriched in the peroxisomal membrane of rat hepatocytes.
Woudenberg J, Rembacz KP, van den Heuvel FA, Woudenberg-Vrenken TE, Buist-Homan M, Geuken M, Hoekstra M, Deelman LE, Enrich C, Henning RH, Moshage H, Faber KN
Hepatology. 2010
PubMed ID: 20146263
Effects of probiotics, prebiotics, and synbiotics on messenger RNA expression of caveolin-1, NOS, and genes regulating oxidative stress in the terminal ileum of formula-fed neonatal rats.
D'Souza A, Fordjour L, Ahmad A, Cai C, Kumar D, Valencia G, Aranda JV, Beharry KD
Pediatr Res. 2010
PubMed ID: 20101198
Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects.
Blouin CM, Le Lay S, Eberl A, Köfeler HC, Guerrera IC, Klein C, Le Liepvre X, Lasnier F, Bourron O, Gautier JF, Ferré P, Hajduch E, Dugail I
J Lipid Res. 2010
PubMed ID: 19965594
Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane.
Hu T, Li C, Cao Z, Van Raay TJ, Smith JG, Willert K, Solnica-Krezel L, Coffey RJ
J Biol Chem. 2010
PubMed ID: 20177058
Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure.
Moore J, McKnight AJ, Simmonds MJ, Courtney AE, Hanvesakul R, Brand OJ, Briggs D, Ball S, Cockwell P, Patterson CC, Maxwell AP, Gough SC, Borrows R
JAMA. 2010
PubMed ID: 20371787
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo.
Marchiando AM, Shen L, Graham WV, Weber CR, Schwarz BT, Austin JR, Raleigh DR, Guan Y, Watson AJ, Montrose MH, Turner JR
J Cell Biol. 2010
PubMed ID: 20351069
[Expression of caveolin-1 and extracellular matrix induced by transforming growth factor beta1 in human fetal lung fibroblasts].
Ding H, Zhou FQ, Cai HR, Zhou YH, Meng FQ
Zhonghua Jie He He Hu Xi Za Zhi. 2010
PubMed ID: 20646460
Targeted mutation of Cav-1 alleviates the effect of endotoxin in the inhibition of ET-1-mediated eNOS activation in the liver.
Kwok W, Clemens MG
Shock. 2010
PubMed ID: 19730165
Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.
Roberts KE, Kawut SM, Krowka MJ, Brown RS, Trotter JF, Shah V, Peter I, Tighiouart H, Mitra N, Handorf E, Knowles JA, Zacks S, Fallon MB, Pulmonary Vascular Complications of Liver Disease Study Group
Gastroenterology. 2010
PubMed ID: 20346360
Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice.
Zhang M, Liu X, Zhang Y, Zhao J
Dev Biol. 2010
PubMed ID: 20060823
Association of caveolin-1 and -2 genetic variants and post-treatment serum caveolin-1 with prostate cancer risk and outcomes.
Langeberg WJ, Tahir SA, Feng Z, Kwon EM, Ostrander EA, Thompson TC, Stanford JL
Prostate. 2010
PubMed ID: 20209490
Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II.
Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH
Endocrinology. 2010
PubMed ID: 20097717
Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells.
Han F, Zhu HG
J Surg Res. 2010
PubMed ID: 20031158
Upregulation of caveolin-1 expression is associated with structural modifications of endothelial cells in diabetic lung.
Uyy E, Antohe F, Ivan L, Haraba R, Radu DL, Simionescu M
Microvasc Res. 2010
PubMed ID: 20004673
MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation.
Lanciotti A, Brignone MS, Camerini S, Serafini B, Macchia G, Raggi C, Molinari P, Crescenzi M, Musumeci M, Sargiacomo M, Aloisi F, Petrucci TC, Ambrosini E
Neurobiol Dis. 2010
PubMed ID: 19931615
The role of caveolin-1 in prostate cancer: clinical implications.
Thompson TC, Tahir SA, Li L, Watanabe M, Naruishi K, Yang G, Kadmon D, Logothetis CJ, Troncoso P, Ren C, Goltsov A, Park S
Prostate Cancer Prostatic Dis. 2010
PubMed ID: 19581923
Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling.
Hu M, Sun XJ, Zhang YL, Kuang Y, Hu CQ, Wu WL, Shen SH, Du TT, Li H, He F, Xiao HS, Wang ZG, Liu TX, Lu H, Huang QH, Chen SJ, Chen Z
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20133625
Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration.
Mayoral R, Valverde AM, Llorente Izquierdo C, González-Rodríguez A, Boscá L, Martín-Sanz P
J Biol Chem. 2010
PubMed ID: 19966340
Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses.
Barzan D, Maier P, Zeller WJ, Wenz F, Herskind C
Strahlenther Onkol. 2010
PubMed ID: 20127227
Several common variants modulate heart rate, PR interval and QRS duration.
Holm H, Gudbjartsson DF, Arnar DO, Thorleifsson G, Thorgeirsson G, Stefansdottir H, Gudjonsson SA, Jonasdottir A, Mathiesen EB, Njølstad I, Nyrnes A, Wilsgaard T, Hald EM, Hveem K, Stoltenberg C, Løchen ML, Kong A, Thorsteinsdottir U, Stefansson K
Nat Genet. 2010
PubMed ID: 20062063
Genome-wide association study of PR interval.
Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Ellinor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR
Nat Genet. 2010
PubMed ID: 20062060
Developmental iodine deficiency and hypothyroidism impair neural development, up-regulate caveolin-1 and down-regulate synaptophysin in rat hippocampus.
Gong J, Dong J, Wang Y, Xu H, Wei W, Zhong J, Liu W, Xi Q, Chen J
J Neuroendocrinol. 2010
PubMed ID: 20025630
The expression of caveolin-1 and the distribution of caveolae in the murine placenta and yolk sac: parallels to the human placenta.
Mohanty S, Anderson CL, Robinson JM
Placenta. 2010
PubMed ID: 20004972
Caveolin-1 facilitates cyclooxygenase-2 protein degradation.
Chen SF, Liou JY, Huang TY, Lin YS, Yeh AL, Tam K, Tsai TH, Wu KK, Shyue SK
J Cell Biochem. 2010
PubMed ID: 19960513
Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance.
Thomas NB, Hutcheson IR, Campbell L, Gee J, Taylor KM, Nicholson RI, Gumbleton M
Breast Cancer Res Treat. 2010
PubMed ID: 19288272
Static pressure drives proliferation of vascular smooth muscle cells via caveolin-1/ERK1/2 pathway.
Luo DX, Cheng J, Xiong Y, Li J, Xia C, Xu C, Wang C, Zhu B, Hu Z, Liao DF
Biochem Biophys Res Commun. 2010
PubMed ID: 20044047
Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation.
Tirado OM, MacCarthy CM, Fatima N, Villar J, Mateo-Lozano S, Notario V
Int J Cancer. 2010
PubMed ID: 19609943
RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling.
Balasubramanian N, Meier JA, Scott DW, Norambuena A, White MA, Schwartz MA
Curr Biol. 2010
PubMed ID: 20005108
Loss of caveolin-1 accelerates neurodegeneration and aging.
Head BP, Peart JN, Panneerselvam M, Yokoyama T, Pearn ML, Niesman IR, Bonds JA, Schilling JM, Miyanohara A, Headrick J, Ali SS, Roth DM, Patel PM, Patel HH
PLoS One. 2010
PubMed ID: 21203469
IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.
Salani B, Passalacqua M, Maffioli S, Briatore L, Hamoudane M, Contini P, Cordera R, Maggi D
PLoS One. 2010
PubMed ID: 21152401
Mutational profile of the CAV-1 gene in breast cancer cases in the ethnic Kashmiri population.
Syeed N, Husain SA, Abdullah S, Sameer AS, Chowdri NA, Nanda MS, Siddiqi MA
Asian Pac J Cancer Prev. 2010
PubMed ID: 21133631
Caveolin-1 promotes mammary tumorigenesis: mutational profile of the Kashmiri population.
Syeed N, Husain SA, Abdullah S, Sameer AS, Chowdri NA, Nanda MS, Siddiqi MA
Asian Pac J Cancer Prev. 2010
PubMed ID: 21039037
Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining.
Zhu H, Yue J, Pan Z, Wu H, Cheng Y, Lu H, Ren X, Yao M, Shen Z, Yang JM
PLoS One. 2010
PubMed ID: 20700465
Expression of caveolin-1 in tongue squamous cell carcinoma by quantum dots.
Xue J, Chen H, Diao L, Chen X, Xia D
Eur J Histochem. 2010
PubMed ID: 20558341
Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA.
Xu Y, Krause A, Hamai H, Harvey BG, Worgall TS, Worgall S
PLoS One. 2010
PubMed ID: 20543983
Downregulation of caveolin-1 enhances fusion of human BeWo choriocarcinoma cells.
Collett GP, Linton EA, Redman CW, Sargent IL
PLoS One. 2010
PubMed ID: 20463894
Liver sinusoidal endothelial fenestrations in caveolin-1 knockout mice.
Warren A, Cogger VC, Arias IM, McCuskey RS, Le Couteur DG
Microcirculation. 2010
PubMed ID: 20141598
Caveolin-1 exists and may function in cardiomyocytes.
Cho WJ, Chow AK, Schulz R, Daniel EE
Can J Physiol Pharmacol. 2010
PubMed ID: 20130741
Caveolin-1 modifies the immunity to Pseudomonas aeruginosa.
Gadjeva M, Paradis-Bleau C, Priebe GP, Fichorova R, Pier GB
J Immunol. 2010
PubMed ID: 19949109
Hepatitis B virus requires intact caveolin-1 function for productive infection in HepaRG cells.
Macovei A, Radulescu C, Lazar C, Petrescu S, Durantel D, Dwek RA, Zitzmann N, Nichita NB
J Virol. 2010
PubMed ID: 19846513
GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells.
Prinetti A, Aureli M, Illuzzi G, Prioni S, Nocco V, Scandroglio F, Gagliano N, Tredici G, Rodriguez-Menendez V, Chigorno V, Sonnino S
Glycobiology. 2010
PubMed ID: 19759399
PPARgamma1-induced caveolin-1 enhances cholesterol efflux and attenuates atherosclerosis in apolipoprotein E-deficient mice.
Hu Q, Zhang XJ, Liu CX, Wang XP, Zhang Y
J Vasc Res. 2010
PubMed ID: 19729954
Change in P-glycoprotein and caveolin protein expression in brain striatum capillaries in New Zealand obese mice with type 2 diabetes.
Wu KC, Pan HJ, Yin HS, Chen MR, Lu SC, Lin CJ
Life Sci. 2009
PubMed ID: 19891976
Integrative predictive model of coronary artery calcification in atherosclerosis.
McGeachie M, Ramoni RL, Mychaleckyj JC, Furie KL, Dreyfuss JM, Liu Y, Herrington D, Guo X, Lima JA, Post W, Rotter JI, Rich S, Sale M, Ramoni MF
Circulation. 2009
PubMed ID: 19948975
Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta3-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes.
Ahmad F, Lindh R, Tang Y, Ruishalme I, Ost A, Sahachartsiri B, Strålfors P, Degerman E, Manganiello VC
Biochem J. 2009
PubMed ID: 19747167
Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium.
Singleton PA, Pendyala S, Gorshkova IA, Mambetsariev N, Moitra J, Garcia JG, Natarajan V
J Biol Chem. 2009
PubMed ID: 19833721
Genetic ablation of caveolin-1 increases neural stem cell proliferation in the subventricular zone (SVZ) of the adult mouse brain.
Jasmin JF, Yang M, Iacovitti L, Lisanti MP
Cell Cycle. 2009
PubMed ID: 19923909
Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence.
Volonte D, Galbiati F
EMBO Rep. 2009
PubMed ID: 19820694
Caveolin-1 expression in diffuse gliomas: correlation with the proliferation index, epidermal growth factor receptor, p53, and 1p/19q status.
Barresi V, Buttarelli FR, Vitarelli EE, Arcella A, Antonelli M, Giangaspero F
Hum Pathol. 2009
PubMed ID: 19716156
Skew in the human caveolin 1 gene upstream purine complex homozygote haplotype compartment in multiple sclerosis.
Zarif Yeganeh M, Ghaffarpour M, Farhud DD, Karimlou M, Ghabaee M, Haghighi Nazari A, Najmabadi H, Ohadi M
J Neuroimmunol. 2009
PubMed ID: 19828204
Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane.
Oakley FD, Smith RL, Engelhardt JF
J Biol Chem. 2009
PubMed ID: 19801678
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.
Pani B, Ong HL, Brazer SC, Liu X, Rauser K, Singh BB, Ambudkar IS
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19897728
A conserved sequence in caveolin-1 is both necessary and sufficient for caveolin polarity and cell directional migration.
Sun XH, Liu ZY, Chen H, Beardsley AR, Qi Q, Liu J
FEBS Lett. 2009
PubMed ID: 19854179
Lipid rafts and caveolin-1 are required for invadopodia formation and extracellular matrix degradation by human breast cancer cells.
Yamaguchi H, Takeo Y, Yoshida S, Kouchi Z, Nakamura Y, Fukami K
Cancer Res. 2009
PubMed ID: 19887621
Caveolin-1 mediates endotoxin inhibition of endothelin-1-induced endothelial nitric oxide synthase activity in liver sinusoidal endothelial cells.
Kwok W, Lee SH, Culberson C, Korneszczuk K, Clemens MG
Am J Physiol Gastrointest Liver Physiol. 2009
PubMed ID: 20501440
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Synergistic effects of lovastatin and celecoxib on caveolin-1 and its down-stream signaling molecules: Implications for colon cancer prevention.
Guruswamy S, Rao CV
Int J Oncol. 2009
PubMed ID: 19787257
Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways.
Zhang M, Lin L, Lee SJ, Mo L, Cao J, Ifedigbo E, Jin Y
Am J Physiol Lung Cell Mol Physiol. 2009
PubMed ID: 19767411
Expression of caveolin-1 in hepatic cells increases oxidized LDL uptake and preserves the expression of lipoprotein receptors.
Truong TQ, Brodeur MR, Falstrault L, Rhainds D, Brissette L
J Cell Biochem. 2009
PubMed ID: 19718657
Caveolin-1 and lipid microdomains regulate Gs trafficking and attenuate Gs/adenylyl cyclase signaling.
Allen JA, Yu JZ, Dave RH, Bhatnagar A, Roth BL, Rasenick MM
Mol Pharmacol. 2009
PubMed ID: 19696145
The DNA methylome of pediatric acute lymphoblastic leukemia.
Davidsson J, Lilljebjörn H, Andersson A, Veerla S, Heldrup J, Behrendtz M, Fioretos T, Johansson B
Hum Mol Genet. 2009
PubMed ID: 19679565
Caveolin-1 and altered neuregulin signaling contribute to the pathophysiological progression of diabetic peripheral neuropathy.
McGuire JF, Rouen S, Siegfreid E, Wright DE, Dobrowsky RT
Diabetes. 2009
PubMed ID: 19675140
Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients.
Du ZM, Hu CF, Shao Q, Huang MY, Kou CW, Zhu XF, Zeng YX, Shao JY
Int J Cancer. 2009
PubMed ID: 19582878
Cholesterol-dependent regulation of adenosine A(2A) receptor-mediated anion secretion in colon epithelial cells.
Lam RS, Nahirney D, Duszyk M
Exp Cell Res. 2009
PubMed ID: 19523941
Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1.
Chanvorachote P, Nimmannit U, Lu Y, Talbott S, Jiang BH, Rojanasakul Y
J Biol Chem. 2009
PubMed ID: 19706615
[Over-expression of caveolin-1 inhibits proliferation and invasion of pancreatic carcinoma cells in vitro].
Han F, Zhu HG
Zhonghua Zhong Liu Za Zhi. 2009
PubMed ID: 20021823
Caveolin-1 acts as a tumor suppressor by down-regulating epidermal growth factor receptor-mitogen-activated protein kinase signaling pathway in pancreatic carcinoma cell lines.
Han F, Gu D, Chen Q, Zhu H
Pancreas. 2009
PubMed ID: 19893453
Vascular permeability and pathological angiogenesis in caveolin-1-null mice.
Chang SH, Feng D, Nagy JA, Sciuto TE, Dvorak AM, Dvorak HF
Am J Pathol. 2009
PubMed ID: 19729487
Caveolin-1 is an important factor for the metastasis and proliferation of human small cell lung cancer NCI-H446 cell.
Yeh D, Chen C, Sun MZ, Shao S, Hao L, Song Y, Gong L, Hu J, Wang Q
Anat Rec (Hoboken). 2009
PubMed ID: 19718715
Augmentation of Cav1 channel current and action potential duration after uptake of S100A1 in sympathetic ganglion neurons.
Hernández-Ochoa EO, Prosser BL, Wright NT, Contreras M, Weber DJ, Schneider MF
Am J Physiol Cell Physiol. 2009
PubMed ID: 19657060
Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation.
Orlichenko L, Weller SG, Cao H, Krueger EW, Awoniyi M, Beznoussenko G, Buccione R, McNiven MA
Mol Biol Cell. 2009
PubMed ID: 19641024
Caveolin-1 plays important role in EGF-induced migration and proliferation of mouse embryonic stem cells: involvement of PI3K/Akt and ERK.
Park JH, Han HJ
Am J Physiol Cell Physiol. 2009
PubMed ID: 19625610
Caveolin-1 tumor-promoting role in human melanoma.
Felicetti F, Parolini I, Bottero L, Fecchi K, Errico MC, Raggi C, Biffoni M, Spadaro F, Lisanti MP, Sargiacomo M, Carè A
Int J Cancer. 2009
PubMed ID: 19521982
NADPH oxidase 1 deficiency alters caveolin phosphorylation and angiotensin II-receptor localization in vascular smooth muscle.
Basset O, Deffert C, Foti M, Bedard K, Jaquet V, Ogier-Denis E, Krause KH
Antioxid Redox Signal. 2009
PubMed ID: 19309260
Phosphorylation of caveolin-1 regulates oxidant-induced pulmonary vascular permeability via paracellular and transcellular pathways.
Sun Y, Hu G, Zhang X, Minshall RD
Circ Res. 2009
PubMed ID: 19713536
Functional analysis of secreted caveolin-1 in mouse models of prostate cancer progression.
Watanabe M, Yang G, Cao G, Tahir SA, Naruishi K, Tabata K, Fattah EA, Rajagopalan K, Timme TL, Park S, Kurosaka S, Edamura K, Tanimoto R, Demayo FJ, Goltsov AA, Thompson TC
Mol Cancer Res. 2009
PubMed ID: 19737975
The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism.
Cerezo A, Guadamillas MC, Goetz JG, Sánchez-Perales S, Klein E, Assoian RK, del Pozo MA
Mol Cell Biol. 2009
PubMed ID: 19620284
Compartmentalizing VEGF-induced ERK2/1 signaling in placental artery endothelial cell caveolae: a paradoxical role of caveolin-1 in placental angiogenesis in vitro.
Liao WX, Feng L, Zhang H, Zheng J, Moore TR, Chen DB
Mol Endocrinol. 2009
PubMed ID: 19477952
Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B sub-unit occurs independently of caveolae.
Lajoie P, Kojic LD, Nim S, Li L, Dennis JW, Nabi IR
J Cell Mol Med. 2009
PubMed ID: 19438805
Overexpression of caveolin-1 in hepatocellular carcinoma with metastasis and worse prognosis: correlation with vascular endothelial growth factor, microvessel density and unpaired artery.
Zhang ZB, Cai L, Zheng SG, Xiong Y, Dong JH
Pathol Oncol Res. 2009
PubMed ID: 19434519
Patients with long bone fracture have altered Caveolin-1 expression in their peripheral blood mononuclear cells.
Tang PF, Burke GA, Li G, Wang Y
Arch Orthop Trauma Surg. 2009
PubMed ID: 19002697
Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation.
Poisson C, Rollin S, Véronneau S, Bousquet SM, Larrivée JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M
J Immunol. 2009
PubMed ID: 19620302
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
Eur Urol. 2009
PubMed ID: 19692168
TRPC1 is regulated by caveolin-1 and is involved in oxidized LDL-induced apoptosis of vascular smooth muscle cells.
Ingueneau C, Huynh UD, Marcheix B, Athias A, Gambert P, Nègre-Salvayre A, Salvayre R, Vindis C
J Cell Mol Med. 2009
PubMed ID: 20187291
An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.
Di Vizio D, Morello M, Sotgia F, Pestell RG, Freeman MR, Lisanti MP
Cell Cycle. 2009
PubMed ID: 19556867
An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells.
Heibeck TH, Ding SJ, Opresko LK, Zhao R, Schepmoes AA, Yang F, Tolmachev AV, Monroe ME, Camp DG, Smith RD, Wiley HS, Qian WJ
J Proteome Res. 2009
PubMed ID: 19534553
Expression of endothelial phosphorylated caveolin-1 is increased in brain injury.
Nag S, Manias JL, Stewart DJ
Neuropathol Appl Neurobiol. 2009
PubMed ID: 19508446
Human papillomavirus type 16 infection of human keratinocytes requires clathrin and caveolin-1 and is brefeldin a sensitive.
Laniosz V, Dabydeen SA, Havens MA, Meneses PI
J Virol. 2009
PubMed ID: 19494002
Caveolin-1 regulates EGFR signaling in MCF-7 breast cancer cells and enhances gefitinib-induced tumor cell inhibition.
Agelaki S, Spiliotaki M, Markomanolaki H, Kallergi G, Mavroudis D, Georgoulias V, Stournaras C
Cancer Biol Ther. 2009
PubMed ID: 19483462
Increased PEA3/E1AF and decreased Net/Elk-3, both ETS proteins, characterize human NSCLC progression and regulate caveolin-1 transcription in Calu-1 and NCI-H23 NSCLC cell lines.
Sloan KA, Marquez HA, Li J, Cao Y, Hinds A, O'Hara CJ, Kathuria S, Ramirez MI, Williams MC, Kathuria H
Carcinogenesis. 2009
PubMed ID: 19483189
Unaltered size selectivity of the glomerular filtration barrier in caveolin-1 knockout mice.
Grände G, Rippe C, Rippe A, Rahman A, Swärd K, Rippe B
Am J Physiol Renal Physiol. 2009
PubMed ID: 19474194
Growth suppression by ursodeoxycholic acid involves caveolin-1 enhanced degradation of EGFR.
Feldman R, Martinez JD
Biochim Biophys Acta. 2009
PubMed ID: 19446582
Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice.
Senou M, Costa MJ, Massart C, Thimmesch M, Khalifa C, Poncin S, Boucquey M, Gérard AC, Audinot JN, Dessy C, Ruf J, Feron O, Devuyst O, Guiot Y, Dumont JE, Van Sande J, Many MC
Am J Physiol Endocrinol Metab. 2009
PubMed ID: 19435853
Caveolin-1 loss of function accelerates glucose transporter 4 and insulin receptor degradation in 3T3-L1 adipocytes.
González-Muñoz E, López-Iglesias C, Calvo M, Palacín M, Zorzano A, Camps M
Endocrinology. 2009
PubMed ID: 19406948
Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa.
Bajmoczi M, Gadjeva M, Alper SL, Pier GB, Golan DE
Am J Physiol Cell Physiol. 2009
PubMed ID: 19386787
Caveolin-1-dependent and -independent membrane domains.
Le Lay S, Li Q, Proschogo N, Rodriguez M, Gunaratnam K, Cartland S, Rentero C, Jessup W, Mitchell T, Gaus K
J Lipid Res. 2009
PubMed ID: 19074371
PTEN identified as important risk factor of chronic obstructive pulmonary disease.
Hosgood HD, Menashe I, He X, Chanock S, Lan Q
Respir Med. 2009
PubMed ID: 19625176
Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing.
Yudoh K, Shi Y, Karasawa R
Int J Rheum Dis. 2009
PubMed ID: 20374325
Caveolin-1 expression in lung carcinoma varies according to tumour histotype and is acquired de novo in brain metastases.
Cassoni P, Daniele L, Maldi E, Righi L, Tavaglione V, Novello S, Volante M, Scagliotti GV, Papotti M
Histopathology. 2009
PubMed ID: 19614763
Caveolin-1 is a novel immunohistochemical marker to differentiate epithelioid mesothelioma from lung adenocarcinoma.
Amatya VJ, Takeshima Y, Kohno H, Kushitani K, Yamada T, Morimoto C, Inai K
Histopathology. 2009
PubMed ID: 19614762
Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis.
Fernández-Hernando C, Yu J, Suárez Y, Rahner C, Dávalos A, Lasunción MA, Sessa WC
Cell Metab. 2009
PubMed ID: 19583953
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration.
Zhao YY, Zhao YD, Mirza MK, Huang JH, Potula HH, Vogel SM, Brovkovych V, Yuan JX, Wharton J, Malik AB
J Clin Invest. 2009
PubMed ID: 19487814
PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway.
Pantera B, Bini C, Cirri P, Paoli P, Camici G, Manao G, Caselli A
J Neurochem. 2009
PubMed ID: 19457127
Large-scale proteomics analysis of the human kinome.
Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H
Mol Cell Proteomics. 2009
PubMed ID: 19369195
Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation.
Xu Y, Yang G, Hu G
Acta Biochim Biophys Sin (Shanghai). 2009
PubMed ID: 19499152
Stromal cell expression of caveolin-1 predicts outcome in breast cancer.
Sloan EK, Ciocca DR, Pouliot N, Natoli A, Restall C, Henderson MA, Fanelli MA, Cuello-Carrión FD, Gago FE, Anderson RL
Am J Pathol. 2009
PubMed ID: 19411449
An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers.
Witkiewicz AK, Dasgupta A, Sotgia F, Mercier I, Pestell RG, Sabel M, Kleer CG, Brody JR, Lisanti MP
Am J Pathol. 2009
PubMed ID: 19411448
Caveolin-1 directly interacts with UT-A1 urea transporter: the role of caveolae/lipid rafts in UT-A1 regulation at the cell membrane.
Feng X, Huang H, Yang Y, Fröhlich O, Klein JD, Sands JM, Chen G
Am J Physiol Renal Physiol. 2009
PubMed ID: 19369293
Filling up adipocytes with lipids. Lessons from caveolin-1 deficiency.
Le Lay S, Blouin CM, Hajduch E, Dugail I
Biochim Biophys Acta. 2009
PubMed ID: 19038362
Novel extreme homozygote haplotypes at the human caveolin 1 gene upstream purine complex in sporadic Alzheimer's disease.
Zarif Yeganeh M, Mirabzadeh A, Khorram Khorshid HR, Kamali K, Heshmati Y, Gozalpour E, Veissy K, Olad Nabi M, Najmabadi H, Ohadi M
Am J Med Genet B Neuropsychiatr Genet. 2009
PubMed ID: 19475601
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP
Am J Pathol. 2009
PubMed ID: 19395651
Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation.
Mercier I, Bryant KG, Sotgia F, Bonuccelli G, Witkiewicz AK, Dasgupta A, Jasmin JF, Pestell RG, Lisanti MP
Cell Cycle. 2009
PubMed ID: 19342880
Caveolin, GLUT4 and insulin receptor protein content in human arm and leg muscles.
Kim HS, Kim HJ, Kim YS, Park SC, Harris R, Kim CK
Eur J Appl Physiol. 2009
PubMed ID: 19219452
Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
Environ Mol Mutagen. 2009
PubMed ID: 19170196
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ
Mol Cell Proteomics. 2009
PubMed ID: 19131326
Caveolin-1-dependent apoptosis induced by fibrin degradation products.
Guo YH, Hernandez I, Isermann B, Kang TB, Medved L, Sood R, Kerschen EJ, Holyst T, Mosesson MW, Weiler H
Blood. 2009
PubMed ID: 19074731
Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.
Singleton PA, Chatchavalvanich S, Fu P, Xing J, Birukova AA, Fortune JA, Klibanov AM, Garcia JG, Birukov KG
Circ Res. 2009
PubMed ID: 19286607
ABCA1 modulates the oligomerization and Golgi exit of caveolin-1 during HDL-mediated cholesterol efflux in aortic endothelial cells.
Lin YC, Lin CH, Kuo CY, Yang VC
Biochem Biophys Res Commun. 2009
PubMed ID: 19275878
SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.
McMahon KA, Zajicek H, Li WP, Peyton MJ, Minna JD, Hernandez VJ, Luby-Phelps K, Anderson RG
EMBO J. 2009
PubMed ID: 19262564
NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development.
Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G
J Cell Sci. 2009
PubMed ID: 19299468
Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa.
Zaas DW, Swan ZD, Brown BJ, Li G, Randell SH, Degan S, Sunday ME, Wright JR, Abraham SN
J Biol Chem. 2009
PubMed ID: 19211560
Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
Mercier I, Casimiro MC, Zhou J, Wang C, Plymire C, Bryant KG, Daumer KM, Sotgia F, Bonuccelli G, Witkiewicz AK, Lin J, Tran TH, Milliman J, Frank PG, Jasmin JF, Rui H, Pestell RG, Lisanti MP
Am J Pathol. 2009
PubMed ID: 19342371
Interaction of galectin-1 with caveolae induces mouse embryonic stem cell proliferation through the Src, ERas, Akt and mTOR signaling pathways.
Lee MY, Lee SH, Park JH, Han HJ
Cell Mol Life Sci. 2009
PubMed ID: 19266163
Caveolin-1-mediated suppression of cyclooxygenase-2 via a beta-catenin-Tcf/Lef-dependent transcriptional mechanism reduced prostaglandin E2 production and survivin expression.
Rodriguez DA, Tapia JC, Fernandez JG, Torres VA, Muñoz N, Galleguillos D, Leyton L, Quest AF
Mol Biol Cell. 2009
PubMed ID: 19244345
The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels.
Romanenko VG, Roser KS, Melvin JE, Begenisich T
Am J Physiol Cell Physiol. 2009
PubMed ID: 19176762
The "caveolae brake hypothesis" and the epidermal barrier.
Roelandt T, Giddelo C, Heughebaert C, Denecker G, Hupe M, Crumrine D, Kusuma A, Haftek M, Roseeuw D, Declercq W, Feingold KR, Elias PM, Hachem JP
J Invest Dermatol. 2009
PubMed ID: 19005485
The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1.
Wang XM, Kim HP, Nakahira K, Ryter SW, Choi AM
J Immunol. 2009
PubMed ID: 19265160
IGF-I induced rapid recruitment of integrin beta1 to lipid rafts is Caveolin-1 dependent.
Salani B, Briatore L, Contini P, Passalacqua M, Melloni E, Paggi A, Cordera R, Maggi D
Biochem Biophys Res Commun. 2009
PubMed ID: 19250636
Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis.
Alves-Filho JC, Freitas A, Souto FO, Spiller F, Paula-Neto H, Silva JS, Gazzinelli RT, Teixeira MM, Ferreira SH, Cunha FQ
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19234125
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, Minetti C, Frank PG, Jimenez SA, Knudsen ES, Pestell RG, Lisanti MP
Am J Pathol. 2009
PubMed ID: 19234134
Ezetimibe is an inhibitor of tumor angiogenesis.
Solomon KR, Pelton K, Boucher K, Joo J, Tully C, Zurakowski D, Schaffner CP, Kim J, Freeman MR
Am J Pathol. 2009
PubMed ID: 19179610
Sonic hedgehog ligand partners with caveolin-1 for intracellular transport.
Mao H, Diehl AM, Li YX
Lab Invest. 2009
PubMed ID: 19139721
Identification of extracellular delta-catenin accumulation for prostate cancer detection.
Lu Q, Zhang J, Allison R, Gay H, Yang WX, Bhowmick NA, Frelix G, Shappell S, Chen YH
Prostate. 2009
PubMed ID: 19116988
Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells.
Sundivakkam PC, Kwiatek AM, Sharma TT, Minshall RD, Malik AB, Tiruppathi C
Am J Physiol Cell Physiol. 2009
PubMed ID: 19052258
A potential role for caveolin-1 in estradiol-17beta-induced proliferation of mouse embryonic stem cells: involvement of Src, PI3K/Akt, and MAPKs pathways.
Park JH, Lee MY, Han HJ
Int J Biochem Cell Biol. 2009
PubMed ID: 18694845
Caveolin-1 expression is required for the development of pulmonary emphysema through activation of the ATM-p53-p21 pathway.
Volonte D, Kahkonen B, Shapiro S, Di Y, Galbiati F
J Biol Chem. 2009
PubMed ID: 19103597
Flotillin-1 stabilizes caveolin-1 in intestinal epithelial cells.
Vassilieva EV, Ivanov AI, Nusrat A
Biochem Biophys Res Commun. 2009
PubMed ID: 19121286
The role of caveolae and caveolin 1 in calcium handling in pacing and contraction of mouse intestine.
Daniel EE, Eteraf T, Sommer B, Cho WJ, Elyazbi A
J Cell Mol Med. 2009
PubMed ID: 19166483
Caveolin-1 expression determines the route of neutrophil extravasation through skin microvasculature.
Marmon S, Hinchey J, Oh P, Cammer M, de Almeida CJ, Gunther L, Raine CS, Lisanti MP
Am J Pathol. 2009
PubMed ID: 19164603
Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma.
Tanase CP, Dima S, Mihai M, Raducan E, Nicolescu MI, Albulescu L, Voiculescu B, Dumitrascu T, Cruceru LM, Leabu M, Popescu I, Hinescu ME
J Mol Histol. 2009
PubMed ID: 19160064
Endothelial caveolin-1 regulates pathologic angiogenesis in a mouse model of colitis.
Chidlow JH, Greer JJ, Anthoni C, Bernatchez P, Fernadez-Hernando C, Bruce M, Abdelbaqi M, Shukla D, Granger DN, Sessa WC, Kevil CG
Gastroenterology. 2009
PubMed ID: 19111727
Guanosine triphosphate cyclohydrolase I expression and enzymatic activity are present in caveolae of endothelial cells.
Peterson TE, d'Uscio LV, Cao S, Wang XL, Katusic ZS
Hypertension. 2009
PubMed ID: 19104007
Caveolin-1 and Rac regulate endothelial capillary-like tubular formation and fenestral contraction in sinusoidal endothelial cells.
Yokomori H, Oda M, Yoshimura K, Nagai T, Fujimaki K, Watanabe S, Hibi T
Liver Int. 2009
PubMed ID: 19067793
Promotion of autophagy and inhibition of apoptosis by low concentrations of cadmium in vascular endothelial cells.
Dong Z, Wang L, Xu J, Li Y, Zhang Y, Zhang S, Miao J
Toxicol In Vitro. 2009
PubMed ID: 19061949
Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia.
Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL
Hum Mol Genet. 2009
PubMed ID: 18996916
Caveolin-1 regulates glioblastoma aggressiveness through the control of alpha(5)beta(1) integrin expression and modulates glioblastoma responsiveness to SJ749, an alpha(5)beta(1) integrin antagonist.
Martin S, Cosset EC, Terrand J, Maglott A, Takeda K, Dontenwill M
Biochim Biophys Acta. 2009
PubMed ID: 18992284
Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death.
Jin Y, Kim HP, Cao J, Zhang M, Ifedigbo E, Choi AM
FASEB J. 2009
PubMed ID: 18801924
Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway.
Chen RS, Song YM, Zhou ZY, Tong T, Li Y, Fu M, Guo XL, Dong LJ, He X, Qiao HX, Zhan QM, Li W
Oncogene. 2009
PubMed ID: 19015640
Interaction of the immunoglobulin-like cell adhesion molecule hepaCAM with caveolin-1.
Moh MC, Lee LH, Zhang T, Shen S
Biochem Biophys Res Commun. 2009
PubMed ID: 19059381
Impaired nerve-mediated relaxation of penile tissue from caveolin-1 deficient mice.
Shakirova Y, Hedlund P, Swärd K
Eur J Pharmacol. 2009
PubMed ID: 19068211
Caveolin-1 activates Rab5 and enhances endocytosis through direct interaction.
Hagiwara M, Shirai Y, Nomura R, Sasaki M, Kobayashi K, Tadokoro T, Yamamoto Y
Biochem Biophys Res Commun. 2009
PubMed ID: 19013132
Caveolin-1 negatively regulates TRAIL-induced apoptosis in human hepatocarcinoma cells.
Zhao X, Liu Y, Ma Q, Wang X, Jin H, Mehrpour M, Chen Q
Biochem Biophys Res Commun. 2009
PubMed ID: 18992712
Disruption of the maxi-K-caveolin-1 interaction alters current expression in human myometrial cells.
Brainard AM, Korovkina VP, England SK
Reprod Biol Endocrinol. 2009
PubMed ID: 19930645
Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels.
Zhang Z, Yao K, Jin C
Mol Vis. 2009
PubMed ID: 19816600
High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.
Logozzi M, De Milito A, Lugini L, Borghi M, Calabrò L, Spada M, Perdicchio M, Marino ML, Federici C, Iessi E, Brambilla D, Venturi G, Lozupone F, Santinami M, Huber V, Maio M, Rivoltini L, Fais S
PLoS One. 2009
PubMed ID: 19381331
Phosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism.
Berger K, Lindh R, Wierup N, Zmuda-Trzebiatowska E, Lindqvist A, Manganiello VC, Degerman E
PLoS One. 2009
PubMed ID: 19262749
Myocardial interstitial Cajal-like cells (ICLC) in caveolin-1 KO mice.
Gherghiceanu M, Hinescu ME, Popescu LM
J Cell Mol Med. 2009
PubMed ID: 19175701
Caveolin-1 expression in human breast lobular cancer progression.
Perrone G, Altomare V, Zagami M, Morini S, Petitti T, Battista C, Muda AO, Rabitti C
Mod Pathol. 2009
PubMed ID: 18836420
Catecholamines relax detrusor through beta 2-adrenoceptors in mouse and beta 3-adrenoceptors in man.
Wuest M, Eichhorn B, Grimm MO, Wirth MP, Ravens U, Kaumann AJ
J Pharmacol Exp Ther. 2009
PubMed ID: 18820136
A high-cholesterol diet increases the association between caveolae and insulin receptors in rat liver.
Hahn-Obercyger M, Graeve L, Madar Z
J Lipid Res. 2009
PubMed ID: 18757837
Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.
Kim HN, Chung HS
BMB Rep. 2008
PubMed ID: 19123976
Nitric oxide synthases are crucially involved in the development of the severe cardiomyopathy of caveolin-1 knockout mice.
Wunderlich C, Schober K, Heerwagen C, Marquetant R, Ebner B, Forkmann M, Schoen S, Braun-Dullaeus RC, Schmeisser A, Strasser RH
Biochem Biophys Res Commun. 2008
PubMed ID: 18951881
Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.
Wang B, Malik R, Nigg EA, Körner R
Anal Chem. 2008
PubMed ID: 19007248
Caveolin-1 expression is a distinct feature of chronic rejection-induced transplant capillaropathy.
Yamamoto I, Horita S, Takahashi T, Kobayashi A, Toki D, Tanabe K, Hattori M, Teraoka S, Aita K, Nagata M, Yamaguchi Y
Am J Transplant. 2008
PubMed ID: 19032226
Caveolin-1 immuno-expression in human gastric cancer: histopathogenetic hypotheses.
Barresi V, Giuffre' G, Vitarelli E, Todaro P, Tuccari G
Virchows Arch. 2008
PubMed ID: 18936967
The role of caveolin-1 in pulmonary matrix remodeling and mechanical properties.
Le Saux O, Teeters K, Miyasato S, Choi J, Nakamatsu G, Richardson JA, Starcher B, Davis EC, Tam EK, Jourdan-Le Saux C
Am J Physiol Lung Cell Mol Physiol. 2008
PubMed ID: 18849439
Freeze-fracture replica immunolabelling reveals caveolin-1 in the human cardiomyocyte plasma membrane.
Robenek H, Weissen-Plenz G, Severs NJ
J Cell Mol Med. 2008
PubMed ID: 18793348
Wild-type APC regulates caveolin-1 expression in human colon adenocarcinoma cell lines via FOXO1a and C-myc.
Roy UK, Henkhaus RS, Ignatenko NA, Mora J, Fultz KE, Gerner EW
Mol Carcinog. 2008
PubMed ID: 18444242
Restoration of caveolin-1 expression suppresses growth and metastasis of head and neck squamous cell carcinoma.
Zhang H, Su L, Müller S, Tighiouart M, Xu Z, Zhang X, Shin HJ, Hunt J, Sun SY, Shin DM, Chen ZG
Br J Cancer. 2008
PubMed ID: 19002186
A dual role for caveolin-1 in the regulation of fibronectin matrix assembly by uPAR.
Monaghan-Benson E, Mastick CC, McKeown-Longo PJ
J Cell Sci. 2008
PubMed ID: 18957516
IL-6/sIL-6R enhances cathepsin B and L production via caveolin-1-mediated JNK-AP-1 pathway in human gingival fibroblasts.
Yamaguchi T, Naruishi K, Arai H, Nishimura F, Takashiba S
J Cell Physiol. 2008
PubMed ID: 18543249
Co-localization and interaction of human organic anion transporter 4 with caveolin-1 in primary cultured human placental trophoblasts.
Lee WK, Choi JK, Cha SH
Exp Mol Med. 2008
PubMed ID: 18985008
Caveolin-1 regulates BMPRII localization and signaling in vascular smooth muscle cells.
Wertz JW, Bauer PM
Biochem Biophys Res Commun. 2008
PubMed ID: 18725205
Caveolin-1 is essential for glimepiride-induced insulin secretion in the pancreatic betaTC-6 cell line.
Puddu A, Salani B, Cordera R, Viviani GL, Maggi D
Biochem Biophys Res Commun. 2008
PubMed ID: 18703018
Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion.
Joshi B, Strugnell SS, Goetz JG, Kojic LD, Cox ME, Griffith OL, Chan SK, Jones SJ, Leung SP, Masoudi H, Leung S, Wiseman SM, Nabi IR
Cancer Res. 2008
PubMed ID: 18922892
The regulation of the cardiac potassium channel (HERG) by caveolin-1.
Lin J, Lin S, Choy PC, Shen X, Deng C, Kuang S, Wu J, Xu W
Biochem Cell Biol. 2008
PubMed ID: 18923542
Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome.
Witkiewicz AK, Nguyen KH, Dasgupta A, Kennedy EP, Yeo CJ, Lisanti MP, Brody JR
Cell Cycle. 2008
PubMed ID: 18802406
Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
Hosgood HD, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q
Carcinogenesis. 2008
PubMed ID: 18676680
Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoating.
Smith JL, Campos SK, Wandinger-Ness A, Ozbun MA
J Virol. 2008
PubMed ID: 18667513
Caveolin-1 promotes the transformation and anti-apoptotic ability of mouse hepatoma cells.
Wang S, Jia L, Zhou H, Wang X, Zhang J
IUBMB Life. 2008
PubMed ID: 18618588
Modulation of caveolin-1 expression can affect signalling through the phosphatidylinositol 3-kinase/Akt pathway and cellular proliferation in response to insulin-like growth factor I.
Matthews LC, Taggart MJ, Westwood M
Endocrinology. 2008
PubMed ID: 18583416
Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress.
Milovanova T, Chatterjee S, Hawkins BJ, Hong N, Sorokina EM, Debolt K, Moore JS, Madesh M, Fisher AB
Biochim Biophys Acta. 2008
PubMed ID: 18573285
Colocalization of androgen binding protein, oxytocin receptor, caveolin 1 and proliferation marker p21 in benign prostate hyperplasia.
Sendemir E, Herbert Z, Sivukhina E, Zermann DH, Arnold R, Jirikowski GF
Anat Histol Embryol. 2008
PubMed ID: 18312604
Correlative evidence that tumor cell-derived caveolin-1 mediates angiogenesis in meningiomas.
Barresi V, Cerasoli S, Tuccari G
Neuropathology. 2008
PubMed ID: 18282163
Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase.
Cai T, Wang H, Chen Y, Liu L, Gunning WT, Quintas LE, Xie ZJ
J Cell Biol. 2008
PubMed ID: 18794328
Novel subtype of congenital generalized lipodystrophy associated with muscular weakness and cervical spine instability.
Simha V, Agarwal AK, Aronin PA, Iannaccone ST, Garg A
Am J Med Genet A. 2008
PubMed ID: 18698612
Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration.
Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M
Exp Cell Res. 2008
PubMed ID: 18598695
Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis.
Del Galdo F, Sotgia F, de Almeida CJ, Jasmin JF, Musick M, Lisanti MP, Jiménez SA
Arthritis Rheum. 2008
PubMed ID: 18759267
Caveolin-1 is transported to multi-vesicular bodies after albumin-induced endocytosis of caveolae in HepG2 cells.
Botos E, Klumperman J, Oorschot V, Igyártó B, Magyar A, Oláh M, Kiss AL
J Cell Mol Med. 2008
PubMed ID: 18053095
Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism.
Augustus AS, Buchanan J, Gutman E, Rengo G, Pestell RG, Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP
Cell Cycle. 2008
PubMed ID: 18719368
The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1.
Veracini L, Simon V, Richard V, Schraven B, Horejsi V, Roche S, Benistant C
J Cell Biol. 2008
PubMed ID: 18695048
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction.
Barakat S, Turcotte S, Demeule M, Lachambre MP, Régina A, Baggetto LG, Béliveau R
Biochem Biophys Res Commun. 2008
PubMed ID: 18485890
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Mercier I, Casimiro MC, Wang C, Rosenberg AL, Quong J, Minkeu A, Allen KG, Danilo C, Sotgia F, Bonuccelli G, Jasmin JF, Xu H, Bosco E, Aronow B, Witkiewicz A, Pestell RG, Knudsen ES, Lisanti MP
Cancer Biol Ther. 2008
PubMed ID: 18458534
Smooth muscle NOS, colocalized with caveolin-1, modulates contraction in mouse small intestine.
El-Yazbi AF, Cho WJ, Cena J, Schulz R, Daniel EE
J Cell Mol Med. 2008
PubMed ID: 18400048
Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis.
Desjardins F, Lobysheva I, Pelat M, Gallez B, Feron O, Dessy C, Balligand JL
Cardiovasc Res. 2008
PubMed ID: 18349137
Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1.
Jin Y, Kim HP, Chi M, Ifedigbo E, Ryter SW, Choi AM
Am J Respir Cell Mol Biol. 2008
PubMed ID: 18323531
Caveolin-1 regulates human immunodeficiency virus-1 Tat-induced alterations of tight junction protein expression via modulation of the Ras signaling.
Zhong Y, Smart EJ, Weksler B, Couraud PO, Hennig B, Toborek M
J Neurosci. 2008
PubMed ID: 18667611
Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase.
Di Vizio D, Adam RM, Kim J, Kim R, Sotgia F, Williams T, Demichelis F, Solomon KR, Loda M, Rubin MA, Lisanti MP, Freeman MR
Cell Cycle. 2008
PubMed ID: 18635971
Caveolin-1-dependent beta1 integrin endocytosis is a critical regulator of fibronectin turnover.
Shi F, Sottile J
J Cell Sci. 2008
PubMed ID: 18577581
Role of caveolin-1 in the regulation of lipoprotein metabolism.
Frank PG, Pavlides S, Cheung MW, Daumer K, Lisanti MP
Am J Physiol Cell Physiol. 2008
PubMed ID: 18508910
Caveolin-1 increases basal and TGF-beta1-induced expression of type I procollagen through PI-3 kinase/Akt/mTOR pathway in human dermal fibroblasts.
Kim S, Lee Y, Seo JE, Cho KH, Chung JH
Cell Signal. 2008
PubMed ID: 18434090
Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability.
Hu G, Vogel SM, Schwartz DE, Malik AB, Minshall RD
Circ Res. 2008
PubMed ID: 18511851
A novel polymorphic purine complex at the 1.5 kb upstream region of the human caveolin-1 gene and risk of Alzheimer's disease; Extra-short alleles and accumulated allele homozygosity.
Heshmati Y, Mirabzadeh A, Feizzade G, Gilanipour M, Etminan MR, Khoram Khorshid HR, Kamali K, Fakhri M, Moghimi N, Najmabadi H, Ohadi M
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 18561140
Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program.
Matthews L, Berry A, Ohanian V, Ohanian J, Garside H, Ray D
Mol Endocrinol. 2008
PubMed ID: 18308897
Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H(2)O(2)-induced premature senescence and interplay with p38alpha(MAPK).
Chrétien A, Piront N, Delaive E, Demazy C, Ninane N, Toussaint O
FEBS Lett. 2008
PubMed ID: 18439424
Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase.
Bailey KM, Liu J
J Biol Chem. 2008
PubMed ID: 18332144
Caveolin-1 sensitizes vascular smooth muscle cells to mildly oxidized LDL-induced apoptosis.
Ingueneau C, Huynh-Do U, Thiers JC, Nègre-Salvayre A, Salvayre R, Vindis C
Biochem Biophys Res Commun. 2008
PubMed ID: 18328807
[Role of caveolin-1 down-regulation by iRNA in human hepatocyte proliferation]
Ren G, Liu Y, Wang XM, Zhao CH, Zou W
Zhonghua Gan Zang Bing Za Zhi. 2008
PubMed ID: 18510854
HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification.
Shaut CA, Keene DR, Sorensen LK, Li DY, Stadler HS
PLoS Genet. 2008
PubMed ID: 18483557
The adverse cardiopulmonary phenotype of caveolin-1 deficient mice is mediated by a dysfunctional endothelium.
Wunderlich C, Schober K, Schmeisser A, Heerwagen C, Tausche AK, Steinbronn N, Brandt A, Kasper M, Schwencke C, Braun-Dullaeus RC, Strasser RH
J Mol Cell Cardiol. 2008
PubMed ID: 18417152
Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.
Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA
Development. 2008
PubMed ID: 18367557
Immunohistochemical evidence of caveolin-1 expression in the human fetal and neonatal striated muscle and absence in the adult's.
Barresi V, Grosso M, Barresi G
Appl Immunohistochem Mol Morphol. 2008
PubMed ID: 18301242
Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo.
Tourkina E, Richard M, Gööz P, Bonner M, Pannu J, Harley R, Bernatchez PN, Sessa WC, Silver RM, Hoffman S
Am J Physiol Lung Cell Mol Physiol. 2008
PubMed ID: 18203815
Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1-/- mice.
Maniatis NA, Shinin V, Schraufnagel DE, Okada S, Vogel SM, Malik AB, Minshall RD
Am J Physiol Lung Cell Mol Physiol. 2008
PubMed ID: 18192592
Expression changes of CAV1 and EZH2, located on 7q31 approximately q36, are rarely related to genomic alterations in primary prostate carcinoma.
Bachmann N, Haeusler J, Luedeke M, Kuefer R, Perner S, Assum G, Paiss T, Hoegel J, Vogel W, Maier C
Cancer Genet Cytogenet. 2008
PubMed ID: 18406871
Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi.
Cubells L, de Muga SV, Tebar F, Bonventre JV, Balsinde J, Pol A, Grewal T, Enrich C
J Biol Chem. 2008
PubMed ID: 18245088
Altered emotionality, spatial memory and cholinergic function in caveolin-1 knock-out mice.
Gioiosa L, Raggi C, Ricceri L, Jasmin JF, Frank PG, Capozza F, Lisanti MP, Alleva E, Sargiacomo M, Laviola G
Behav Brain Res. 2008
PubMed ID: 18083242
Impact of caveolin-1 expression on the prognosis of transitional cell carcinoma of the upper urinary tract.
Cho DS, Yim H, Cho KS, Hong SJ, Cho NH, Kim SI, Ahn HS, Kim SJ
J Korean Med Sci. 2008
PubMed ID: 18437015
Mice with cav-1 gene disruption have benign stromal lesions and compromised epithelial differentiation.
Yang G, Timme TL, Naruishi K, Fujita T, Fattah el MA, Cao G, Rajocopolan K, Troung LD, Thompson TC
Exp Mol Pathol. 2008
PubMed ID: 18358473
Interactions of acetylcholinesterase with caveolin-1 and subsequently with cytochrome c are required for apoptosome formation.
Park SE, Jeong SH, Yee SB, Kim TH, Soung YH, Ha NC, Kim ND, Park JY, Bae HR, Park BS, Lee HJ, Yoo YH
Carcinogenesis. 2008
PubMed ID: 18258603
Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.
Kim CA, Delépine M, Boutet E, El Mourabit H, Le Lay S, Meier M, Nemani M, Bridel E, Leite CC, Bertola DR, Semple RK, O'Rahilly S, Dugail I, Capeau J, Lathrop M, Magré J
J Clin Endocrinol Metab. 2008
PubMed ID: 18211975
The immunogenic CBD1 peptide corresponding to the caveolin-1 binding domain in HIV-1 envelope gp41 has the capacity to penetrate the cell membrane and bind caveolin-1.
Benferhat R, Sanchez-Martinez S, Nieva JL, Briand JP, Hovanessian AG
Mol Immunol. 2008
PubMed ID: 18054388
Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1.
Goetz JG, Joshi B, Lajoie P, Strugnell SS, Scudamore T, Kojic LD, Nabi IR
J Cell Biol. 2008
PubMed ID: 18347068
Caveolin-1 deficiency alters plasma lipid and lipoprotein profiles in mice.
Heimerl S, Liebisch G, Le Lay S, Böttcher A, Wiesner P, Lindtner S, Kurzchalia TV, Simons K, Schmitz G
Biochem Biophys Res Commun. 2008
PubMed ID: 18191037
Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-alpha following ozone inhalation.
Fakhrzadeh L, Laskin JD, Laskin DL
Toxicol Appl Pharmacol. 2008
PubMed ID: 18207479
Caveolin regulates endocytosis of the muscle repair protein, dysferlin.
Hernández-Deviez DJ, Howes MT, Laval SH, Bushby K, Hancock JF, Parton RG
J Biol Chem. 2008
PubMed ID: 18096699
[The roles of caveolin-1 and endothelial nitric oxide synthase in the development of portal hypertension in rats with liver cirrhosis]
Xu B, Zhu GH, Weng JF, Cai WS, Xia JT, Li SH
Zhonghua Gan Zang Bing Za Zhi. 2008
PubMed ID: 18364076
Caveolin-1: a tumor-promoting role in human cancer.
Shatz M, Liscovitch M
Int J Radiat Biol. 2008
PubMed ID: 18300018
Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice.
Pojoga LH, Yao TM, Sinha S, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 18178722
Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes.
Langlois S, Cowan KN, Shao Q, Cowan BJ, Laird DW
Mol Biol Cell. 2008
PubMed ID: 18162583
Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae.
Santibanez JF, Blanco FJ, Garrido-Martin EM, Sanz-Rodriguez F, del Pozo MA, Bernabeu C
Cardiovasc Res. 2008
PubMed ID: 18065769
Retinoic acid- and phorbol ester-induced neuronal differentiation down-regulates caveolin expression in GnRH neurons.
D'Orlando C, Guzzi F, Gravati M, Biella G, Toselli M, Meneveri R, Barisani D, Parenti M
J Neurochem. 2008
PubMed ID: 17988240
Caveolin-1 expression is essential for N-methyl-D-aspartate receptor-mediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell death.
Head BP, Patel HH, Tsutsumi YM, Hu Y, Mejia T, Mora RC, Insel PA, Roth DM, Drummond JC, Patel PM
FASEB J. 2008
PubMed ID: 17905724
Down-regulation of caveolin-1, an inhibitor of transforming growth factor-beta signaling, in acute allergen-induced airway remodeling.
Le Saux CJ, Teeters K, Miyasato SK, Hoffmann PR, Bollt O, Douet V, Shohet RV, Broide DH, Tam EK
J Biol Chem. 2008
PubMed ID: 18056268
Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.
Saliez J, Bouzin C, Rath G, Ghisdal P, Desjardins F, Rezzani R, Rodella LF, Vriens J, Nilius B, Feron O, Balligand JL, Dessy C
Circulation. 2008
PubMed ID: 18268148
Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression.
Alioua A, Lu R, Kumar Y, Eghbali M, Kundu P, Toro L, Stefani E
J Biol Chem. 2008
PubMed ID: 18079116
Caveolae/caveolin-1 are important modulators of store-operated calcium entry in Hs578/T breast cancer cells.
Zhu H, Weisleder N, Wu P, Cai C, Chen JW
J Pharmacol Sci. 2008
PubMed ID: 18296864
Tumor cell-secreted caveolin-1 has proangiogenic activities in prostate cancer.
Tahir SA, Yang G, Goltsov AA, Watanabe M, Tabata K, Addai J, Fattah el MA, Kadmon D, Thompson TC
Cancer Res. 2008
PubMed ID: 18245473
Regulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cells.
Bianco C, Strizzi L, Mancino M, Watanabe K, Gonzales M, Hamada S, Raafat A, Sahlah L, Chang C, Sotgia F, Normanno N, Lisanti M, Salomon DS
Am J Pathol. 2008
PubMed ID: 18202186
Caveolin-1 down-regulation inhibits insulin-like growth factor-I receptor signal transduction in H9C2 rat cardiomyoblasts.
Salani B, Briatore L, Garibaldi S, Cordera R, Maggi D
Endocrinology. 2008
PubMed ID: 18039791
Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury.
Hu G, Ye RD, Dinauer MC, Malik AB, Minshall RD
Am J Physiol Lung Cell Mol Physiol. 2008
PubMed ID: 17993589
Expression of sex hormone-binding globulin, oxytocin receptor, caveolin-1 and p21 in leiomyoma.
Sendemir A, Sendemir E, Kosmehl H, Jirikowski GF
Gynecol Endocrinol. 2008
PubMed ID: 17952758
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function.
Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VM, Martin S, Hancock JF, Parton RG
Cell. 2008
PubMed ID: 18191225
Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells.
Sowa G, Xie L, Xu L, Sessa WC
Biochemistry. 2008
PubMed ID: 18081315
Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.
Dittmann K, Mayer C, Kehlbach R, Rodemann HP
Mol Cancer. 2008
PubMed ID: 18789131
Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.
Heathfield SK, Le Maitre CL, Hoyland JA
Arthritis Res Ther. 2008
PubMed ID: 18681962
Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease.
Rodriguez-Feo JA, Hellings WE, Moll FL, De Vries JP, van Middelaar BJ, Algra A, Sluijter J, Velema E, van der Broek T, Sessa WC, De Kleijn DP, Pasterkamp G
PLoS ONE. 2008
PubMed ID: 18596970
Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells.
Barth K, Weinhold K, Guenther A, Linge A, Gereke M, Kasper M
Int J Biochem Cell Biol. 2008
PubMed ID: 18407780
Heterozygous CAV1 frameshift mutations (MIM 601047) in patients with atypical partial lipodystrophy and hypertriglyceridemia.
Cao H, Alston L, Ruschman J, Hegele RA
Lipids Health Dis. 2008
PubMed ID: 18237401
Preliminary computational modeling of nitric oxide synthase 3 interactions with caveolin-1: influence of exon 7 Glu298Asp polymorphism.
Joshi MS, Bauer JA
Acta Biochim Biophys Sin (Shanghai). 2008
PubMed ID: 18180853
Differential dependence of stretch and shear stress signaling on caveolin-1 in the vascular wall.
Albinsson S, Nordström I, Swärd K, Hellstrand P
Am J Physiol Cell Physiol. 2008
PubMed ID: 17989209
Caveolin-1 and caveolin-3 form heterooligomeric complexes in atrial cardiac myocytes that are required for doxorubicin-induced apoptosis.
Volonte D, McTiernan CF, Drab M, Kasper M, Galbiati F
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 17982011
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
Cell. 2007
PubMed ID: 18083107
Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats.
Kim H, Moon C, Kim J, Ahn M, Hyun JW, Park JW, Kim SH, Kim S, Shin T
J Vet Sci. 2007
PubMed ID: 17993744
Effect of caveolin-1 scaffolding peptide and 17beta-estradiol on intracellular Ca2+ kinetics evoked by angiotensin II in human vascular smooth muscle cells.
Méndez-Bolaina E, Sánchez-González J, Ramírez-Sánchez I, Ocharán-Hernández E, Núñez-Sánchez M, Meaney-Mendiolea E, Meaney A, Asbun-Bojalil J, Miliar-García A, Olivares-Corichi I, Ceballos-Reyes G
Am J Physiol Cell Physiol. 2007
PubMed ID: 17942630
The role of caveolin-1 in PCB77-induced eNOS phosphorylation in human-derived endothelial cells.
Lim EJ, Smart EJ, Toborek M, Hennig B
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17933968
COX-2 localization within plasma membrane caveolae-like structures in human lobular intraepithelial neoplasia of the breast.
Perrone G, Zagami M, Altomare V, Battista C, Morini S, Rabitti C
Virchows Arch. 2007
PubMed ID: 17851687
Tissue factor induction by protease-activated receptor 1 requires intact caveolin-enriched membrane microdomains in human endothelial cells.
Banfi C, Brioschi M, Barcella S, Pignieri A, Parolari A, Biglioli P, Tremoli E, Mussoni L
J Thromb Haemost. 2007
PubMed ID: 17848177
Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, caveolin-1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cells.
Zhang X, Ling MT, Wang Q, Lau CK, Leung SC, Lee TK, Cheung AL, Wong YC, Wang X
J Biol Chem. 2007
PubMed ID: 17855368
Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation.
Chhipa RR, Kumari R, Upadhyay AK, Bhat MK
Exp Cell Res. 2007
PubMed ID: 17935714
Aromatic residues of Caveolin-1 binding motif of alpha-hemolysin are essential for membrane penetration.
Pany S, Krishnasastry MV
Biochem Biophys Res Commun. 2007
PubMed ID: 17850762
Caveolin-1 is critical for the maturation of tumor blood vessels through the regulation of both endothelial tube formation and mural cell recruitment.
Dewever J, Frérart F, Bouzin C, Baudelet C, Ansiaux R, Sonveaux P, Gallez B, Dessy C, Feron O
Am J Pathol. 2007
PubMed ID: 17916598
E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcription.
Torres VA, Tapia JC, Rodriguez DA, Lladser A, Arredondo C, Leyton L, Quest AF
Mol Cell Biol. 2007
PubMed ID: 17785436
Evidence for a role of caveolin-1 in neurokinin-1 receptor plasma-membrane localization, efficient signaling, and interaction with beta-arrestin 2.
Kubale V, Abramović Z, Pogacnik A, Heding A, Sentjurc M, Vrecl M
Cell Tissue Res. 2007
PubMed ID: 17713785
Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis.
Yang G, Addai J, Wheeler TM, Frolov A, Miles BJ, Kadmon D, Thompson TC
Hum Pathol. 2007
PubMed ID: 17707459
Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown.
Nag S, Venugopalan R, Stewart DJ
Acta Neuropathol. 2007
PubMed ID: 17687559
Caveolin-1 affects serotonin binding and cell surface levels of human 5-HT7(a) receptors.
Sjögren B, Svenningsson P
FEBS Lett. 2007
PubMed ID: 17936759
Caveolin-1 regulates the delivery and endocytosis of the glutamate transporter, excitatory amino acid carrier 1.
González MI, Krizman-Genda E, Robinson MB
J Biol Chem. 2007
PubMed ID: 17715130
Caveolin-1 inhibits the growth of human laryngeal squamous cell carcinoma and down regulates EGFR-MAPKs signaling pathway.
Gu D, Li H, Wang Z, Chen Q, Jiang J, Zhu H
Laryngoscope. 2007
PubMed ID: 17906498
Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice.
Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, Sessa WC
J Exp Med. 2007
PubMed ID: 17893196
High frequency of promoter methylation of the 14-3-3 sigma and CAGE-1 genes, but lack of hypermethylation of the caveolin-1 gene, in primary adenocarcinomas and signet ring cell carcinomas of the urinary bladder.
Kunze E, Schlott T
Int J Mol Med. 2007
PubMed ID: 17786288
The tetraspan protein EMP2 regulates expression of caveolin-1.
Forbes A, Wadehra M, Mareninov S, Morales S, Shimazaki K, Gordon LK, Braun J
J Biol Chem. 2007
PubMed ID: 17609206
Matrix metalloproteinase-2, caveolins, focal adhesion kinase and c-Kit in cells of the mouse myocardium.
Cho WJ, Chow AK, Schulz R, Daniel EE
J Cell Mol Med. 2007
PubMed ID: 17979883
[Expression of caveolin in hepatocellular carcinoma: association with unpaired artery formation and radiologic findings]
Choi HN, Kim KR, Park HS, Jang KY, Kang MJ, Lee DG, Kim YK, Cho BH, Cha EJ, Moon WS
Korean J Hepatol. 2007
PubMed ID: 17898556
Immunocytochemical and biochemical detection of EMMPRIN in the rat tooth germ: differentiation-dependent co-expression with MMPs and co-localization with caveolin-1 in membrane rafts of dental epithelial cells.
Schwab W, Harada H, Goetz W, Nowicki M, Witt M, Kasper M, Barth K
Histochem Cell Biol. 2007
PubMed ID: 17684756
The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma.
Ando T, Ishiguro H, Kimura M, Mitsui A, Mori Y, Sugito N, Tomoda K, Mori R, Harada K, Katada T, Ogawa R, Fujii Y, Kuwabara Y
Oncol Rep. 2007
PubMed ID: 17671707
Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice.
Albinsson S, Shakirova Y, Rippe A, Baumgarten M, Rosengren BI, Rippe C, Hallmann R, Hellstrand P, Rippe B, Swärd K
Am J Physiol Regul Integr Comp Physiol. 2007
PubMed ID: 17626133
Human papillomavirus type 31 uses a caveolin 1- and dynamin 2-mediated entry pathway for infection of human keratinocytes.
Smith JL, Campos SK, Ozbun MA
J Virol. 2007
PubMed ID: 17626097
Caveolin-1 knockout mice have increased bone size and stiffness.
Rubin J, Schwartz Z, Boyan BD, Fan X, Case N, Sen B, Drab M, Smith D, Aleman M, Wong KL, Yao H, Jo H, Gross TS
J Bone Miner Res. 2007
PubMed ID: 17550335
Loss of caveolin-1 in bronchiolization in lung fibrosis.
Odajima N, Betsuyaku T, Nasuhara Y, Nishimura M
J Histochem Cytochem. 2007
PubMed ID: 17478448
Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.
Patel HH, Zhang S, Murray F, Suda RY, Head BP, Yokoyama U, Swaney JS, Niesman IR, Schermuly RT, Pullamsetti SS, Thistlethwaite PA, Miyanohara A, Farquhar MG, Yuan JX, Insel PA
FASEB J. 2007
PubMed ID: 17470567
ERM is expressed by alveolar epithelial cells in adult mouse lung and regulates caveolin-1 transcription in mouse lung epithelial cell lines.
Kathuria H, Cao Y, Hinds A, Ramirez MI, Williams MC
J Cell Biochem. 2007
PubMed ID: 17390339
Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance.
Kabayama K, Sato T, Saito K, Loberto N, Prinetti A, Sonnino S, Kinjo M, Igarashi Y, Inokuchi J
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17699617
Caveolin-1 reduces osteosarcoma metastases by inhibiting c-Src activity and met signaling.
Cantiani L, Manara MC, Zucchini C, De Sanctis P, Zuntini M, Valvassori L, Serra M, Olivero M, Di Renzo MF, Colombo MP, Picci P, Scotlandi K
Cancer Res. 2007
PubMed ID: 17699771
Differential expression of caveolin-1 in renal neoplasms.
Tamaskar I, Choueiri TK, Sercia L, Rini B, Bukowski R, Zhou M
Cancer. 2007
PubMed ID: 17594718
Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.
Di Vizio D, Sotgia F, Williams TM, Hassan GS, Capozza F, Frank PG, Pestell RG, Loda M, Freeman MR, Lisanti MP
Cancer Biol Ther. 2007
PubMed ID: 17786030
Molecular interaction between caveolin-1 and ABCA1 on high-density lipoprotein-mediated cholesterol efflux in aortic endothelial cells.
Lin YC, Ma C, Hsu WC, Lo HF, Yang VC
Cardiovasc Res. 2007
PubMed ID: 17499231
Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells.
Zhang B, Peng F, Wu D, Ingram AJ, Gao B, Krepinsky JC
Cell Signal. 2007
PubMed ID: 17446044
Angiotensin converting enzyme 2 is primarily epithelial and is developmentally regulated in the mouse lung.
Wiener RS, Cao YX, Hinds A, Ramirez MI, Williams MC
J Cell Biochem. 2007
PubMed ID: 17340620
Expression of Caveolin-1 reduces cellular responses to TGF-beta1 through down-regulating the expression of TGF-beta type II receptor gene in NIH3T3 fibroblast cells.
Lee EK, Lee YS, Han IO, Park SH
Biochem Biophys Res Commun. 2007
PubMed ID: 17543885
Cell selective glucocorticoid induction of caveolin-1 and caveolae in differentiating pulmonary alveolar epithelial cell cultures.
Barar J, Campbell L, Hollins AJ, Thomas NP, Smith MW, Morris CJ, Gumbleton M
Biochem Biophys Res Commun. 2007
PubMed ID: 17537407
Caveolin and MAP kinase interaction in angiotensin II preconditioning of the myocardium.
Das M, Das S, Das DK
J Cell Mol Med. 2007
PubMed ID: 17760840
Caveolin-1 is required for lateral line neuromast and notochord development.
Nixon SJ, Carter A, Wegner J, Ferguson C, Floetenmeyer M, Riches J, Key B, Westerfield M, Parton RG
J Cell Sci. 2007
PubMed ID: 17550965
Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts.
Sawada N, Taketani Y, Amizuka N, Ichikawa M, Ogawa C, Nomoto K, Nashiki K, Sato T, Arai H, Isshiki M, Segawa H, Yamamoto H, Miyamoto K, Takeda E
Bone. 2007
PubMed ID: 17448744
Ectopic expression of caveolin-1 restores physiological contractile response of aged colonic smooth muscle.
Somara S, Gilmont RR, Martens JR, Bitar KN
Am J Physiol Gastrointest Liver Physiol. 2007
PubMed ID: 17431219
Caveolin-1 and caveolin-3 regulate Ca2+ homeostasis of single smooth muscle cells from rat cerebral resistance arteries.
Kamishima T, Burdyga T, Gallagher JA, Quayle JM
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17337601
Association of estrogen receptor beta with plasma-membrane caveola components: implication in control of vitamin D receptor.
Gilad LA, Schwartz B
J Mol Endocrinol. 2007
PubMed ID: 17556531
Caveolin-1 influences P2X7 receptor expression and localization in mouse lung alveolar epithelial cells.
Barth K, Weinhold K, Guenther A, Young MT, Schnittler H, Kasper M
FEBS J. 2007
PubMed ID: 17498208
Reggie-1 and reggie-2 localize in non-caveolar rafts in epithelial cells: cellular localization is not dependent on the expression of caveolin proteins.
Fernow I, Icking A, Tikkanen R
Eur J Cell Biol. 2007
PubMed ID: 17482312
Immunohistochemical study on caveolin-1alpha in regenerating process of tubular cells in gentamicin-induced acute tubular injury in rats.
Fujigaki Y, Sakakima M, Sun Y, Goto T, Ohashi N, Fukasawa H, Tsuji T, Yamamoto T, Hishida A
Virchows Arch. 2007
PubMed ID: 17464513
Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells.
Murata T, Lin MI, Stan RV, Bauer PM, Yu J, Sessa WC
J Biol Chem. 2007
PubMed ID: 17416589
Rotavirus NSP4 interacts with both the amino- and carboxyl-termini of caveolin-1.
Mir KD, Parr RD, Schroeder F, Ball JM
Virus Res. 2007
PubMed ID: 17379346
Low molecular weight protein tyrosine phosphatase and caveolin-1: interaction and isoenzyme-dependent regulation.
Caselli A, Taddei ML, Bini C, Paoli P, Camici G, Manao G, Cirri P, Ramponi G
Biochemistry. 2007
PubMed ID: 17469800
Hypertrophy and atrophy inversely regulate Caveolin-3 expression in myoblasts.
Fanzani A, Musarò A, Stoppani E, Giuliani R, Colombo F, Preti A, Marchesini S
Biochem Biophys Res Commun. 2007
PubMed ID: 17418092
Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases.
Grande-García A, Echarri A, de Rooij J, Alderson NB, Waterman-Storer CM, Valdivielso JM, del Pozo MA
J Cell Biol. 2007
PubMed ID: 17517963
Caveolin-1 expression is variably displayed in astroglial-derived tumors and absent in oligodendrogliomas: concrete premises for a new reliable diagnostic marker in gliomas.
Cassoni P, Senetta R, Castellano I, Ortolan E, Bosco M, Magnani I, Ducati A
Am J Surg Pathol. 2007
PubMed ID: 17460461
Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence.
Karam JA, Lotan Y, Roehrborn CG, Ashfaq R, Karakiewicz PI, Shariat SF
Prostate. 2007
PubMed ID: 17299799
Redox regulation of ischemic preconditioning is mediated by the differential activation of caveolins and their association with eNOS and GLUT-4.
Koneru S, Penumathsa SV, Thirunavukkarasu M, Samuel SM, Zhan L, Han Z, Maulik G, Das DK, Maulik N
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17277024
Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1.
Patel HH, Tsutsumi YM, Head BP, Niesman IR, Jennings M, Horikawa Y, Huang D, Moreno AL, Patel PM, Insel PA, Roth DM
FASEB J. 2007
PubMed ID: 17272740
Sustained elevations in NEFA induce cyclooxygenase-2 activity and potentiate THP-1 macrophage foam cell formation.
Lloyd EE, Gaubatz JW, Burns AR, Pownall HJ
Atherosclerosis. 2007
PubMed ID: 16870193
Binding of nuclear caveolin-1 to promoter elements of growth-associated genes in ovarian carcinoma cells.
Sanna E, Miotti S, Mazzi M, De Santis G, Canevari S, Tomassetti A
Exp Cell Res. 2007
PubMed ID: 17359972
Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins.
Macaulay IC, Tijssen MR, Thijssen-Timmer DC, Gusnanto A, Steward M, Burns P, Langford CF, Ellis PD, Dudbridge F, Zwaginga JJ, Watkins NA, van der Schoot CE, Ouwehand WH
Blood. 2007
PubMed ID: 17192395
Increases in the phosphorylated form of caveolin-1 in the spinal cord of rats with clip compression injury.
Shin T
Brain Res. 2007
PubMed ID: 17275798
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks.
Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17389395
Vascular endothelial growth factor receptor-3 activity is modulated by its association with caveolin-1 on endothelial membrane.
Galvagni F, Anselmi F, Salameh A, Orlandini M, Rocchigiani M, Oliviero S
Biochemistry. 2007
PubMed ID: 17348685
Caveolin-1 inhibits matrix metalloproteinase-2 activity in the heart.
Chow AK, Cena J, El-Yazbi AF, Crawford BD, Holt A, Cho WJ, Daniel EE, Schulz R
J Mol Cell Cardiol. 2007
PubMed ID: 17349656
Association of gene polymorphisms with blood pressure and the prevalence of hypertension in community-dwelling Japanese individuals.
Yamada Y, Ando F, Shimokata H
Int J Mol Med. 2007
PubMed ID: 17334644
Modulation of p-glycoprotein function by caveolin-1 phosphorylation.
Barakat S, Demeule M, Pilorget A, Régina A, Gingras D, Baggetto LG, Béliveau R
J Neurochem. 2007
PubMed ID: 17326770
Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.
Nakashima H, Hamamura K, Houjou T, Taguchi R, Yamamoto N, Mitsudo K, Tohnai I, Ueda M, Urano T, Furukawa K, Furukawa K
Cancer Sci. 2007
PubMed ID: 17284246
Reciprocal negative regulation between thyrotropin/3',5'-cyclic adenosine monophosphate-mediated proliferation and caveolin-1 expression in human and murine thyrocytes.
Costa MJ, Senou M, Van Rode F, Ruf J, Capello M, Dequanter D, Lothaire P, Dessy C, Dumont JE, Many MC, Van Sande J
Mol Endocrinol. 2007
PubMed ID: 17202321
Cholesterol depletion inhibits fatty acid uptake without affecting CD36 or caveolin-1 distribution in adipocytes.
Covey SD, Brunet RH, Gandhi SG, McFarlane N, Boreham DR, Gerber GE, Trigatti BL
Biochem Biophys Res Commun. 2007
PubMed ID: 17291449
Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.
Ohnuma K, Uchiyama M, Yamochi T, Nishibashi K, Hosono O, Takahashi N, Kina S, Tanaka H, Lin X, Dang NH, Morimoto C
J Biol Chem. 2007
PubMed ID: 17287217
Caveolin-1 deficiency increases cerebral ischemic injury.
Jasmin JF, Malhotra S, Singh Dhallu M, Mercier I, Rosenbaum DM, Lisanti MP
Circ Res. 2007
PubMed ID: 17293479
Increased phosphorylation of caveolin-1 in the sciatic nerves of Lewis rats with experimental autoimmune neuritis.
Kim H, Moon C, Ahn M, Matsumoto Y, Koh CS, Kim MD, Shin T
Brain Res. 2007
PubMed ID: 17234162
Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth.
Lin MI, Yu J, Murata T, Sessa WC
Cancer Res. 2007
PubMed ID: 17363608
Identification of the HIV-1 gp41 core-binding motif in the scaffolding domain of caveolin-1.
Huang JH, Lu L, Lu H, Chen X, Jiang S, Chen YH
J Biol Chem. 2007
PubMed ID: 17197700
Activated epidermal growth factor receptor induces integrin alpha2 internalization via caveolae/raft-dependent endocytic pathway.
Ning Y, Buranda T, Hudson LG
J Biol Chem. 2007
PubMed ID: 17179151
Immune dysfunction in caveolin-1 null mice following infection with Trypanosoma cruzi (Tulahuen strain).
Medina FA, Cohen AW, de Almeida CJ, Nagajyothi F, Braunstein VL, Teixeira MM, Tanowitz HB, Lisanti MP
Microbes Infect. 2007
PubMed ID: 17317261
Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways.
Wang MD, Kiss RS, Franklin V, McBride HM, Whitman SC, Marcel YL
J Lipid Res. 2007
PubMed ID: 17148552
Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries.
Adebiyi A, Zhao G, Cheranov SY, Ahmed A, Jaggar JH
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17098833
Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity.
Shajahan AN, Wang A, Decker M, Minshall RD, Liu MC, Clarke R
J Biol Chem. 2007
PubMed ID: 17190831
Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells.
Song L, Ge S, Pachter JS
Blood. 2007
PubMed ID: 17023578
Integrins regulate opioid receptor signaling in trigeminal ganglion neurons.
Berg KA, Zardeneta G, Hargreaves KM, Clarke WP, Milam SB
Neuroscience. 2007
PubMed ID: 17157995
Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy.
Bouzin C, Brouet A, De Vriese J, Dewever J, Feron O
J Immunol. 2007
PubMed ID: 17237399
The function of alpha- and beta-adrenoceptors of the saphenous artery in caveolin-1 knockout and wild-type mice.
Neidhold S, Eichhorn B, Kasper M, Ravens U, Kaumann AJ
Br J Pharmacol. 2007
PubMed ID: 17179950
Renal caveolin-1 expression in children with unilateral ureteropelvic junction obstruction.
Vallés PG, Manucha W, Carrizo L, Vega Perugorria J, Seltzer A, Ruete C
Pediatr Nephrol. 2007
PubMed ID: 17111160
Effects of homocysteine on the levels of caveolin-1 and eNOS in caveolae of human coronary artery endothelial cells.
Meye C, Schumann J, Wagner A, Gross P
Atherosclerosis. 2007
PubMed ID: 16616146
Caveolin-1 and lipid rafts in confluent BeWo trophoblasts: evidence for Rock-1 association with caveolin-1.
Rashid-Doubell F, Tannetta D, Redman CW, Sargent IL, Boyd CA, Linton EA
Placenta. 2007
PubMed ID: 16480767
Caveolin-1 and liver regeneration: role in proliferation and lipogenesis.
Frank PG, Lisanti MP
Cell Cycle. 2007
PubMed ID: 17314510
Overexpression of caveolin-1 inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phase.
Fang K, Fu W, Beardsley AR, Sun X, Lisanti MP, Liu J
Cell Cycle. 2007
PubMed ID: 17245131
Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets.
Grayson TH, Ohms SJ, Brackenbury TD, Meaney KR, Peng K, Pittelkow YE, Wilson SR, Sandow SL, Hill CE
BMC Genomics. 2007
PubMed ID: 17986358
Caveolin-1 expression in benign and malignant lesions of the breast.
Liedtke C, Kersting C, Bürger H, Kiesel L, Wülfing P
World J Surg Oncol. 2007
PubMed ID: 17915016
Downregulation of caveolin-1 affects bleomycin-induced growth arrest and cellular senescence in A549 cells.
Linge A, Weinhold K, Bläsche R, Kasper M, Barth K
Int J Biochem Cell Biol. 2007
PubMed ID: 17662641
Different caveolin isoforms in the retina of melanoma malignum affected human eye.
Berta AI, Kiss AL, Kemeny-Beke A, Lukats A, Szabó A, Szél A
Mol Vis. 2007
PubMed ID: 17615539
Caveolin-1 sensitizes rat pituitary adenoma GH3 cells to bromocriptine induced apoptosis.
Jiang YN, Li YH, Ke MW, Tseng TY, Tang YB, Huang MC, Cheng WT, Ju YT
Cancer Cell Int. 2007
PubMed ID: 17331262
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis.
Savage K, Lambros MB, Robertson D, Jones RL, Jones C, Mackay A, James M, Hornick JL, Pereira EM, Milanezi F, Fletcher CD, Schmitt FC, Ashworth A, Reis-Filho JS
Clin Cancer Res. 2007
PubMed ID: 17200343
Caveolin-1(-/-)- and caveolin-2(-/-)-deficient mice both display numerous skeletal muscle abnormalities, with tubular aggregate formation.
Schubert W, Sotgia F, Cohen AW, Capozza F, Bonuccelli G, Bruno C, Minetti C, Bonilla E, Dimauro S, Lisanti MP
Am J Pathol. 2007
PubMed ID: 17200204
Generation of survival signal by differential interaction of p38MAPKalpha and p38MAPKbeta with caveolin-1 and caveolin-3 in the adapted heart.
Das M, Cui J, Das DK
J Mol Cell Cardiol. 2007
PubMed ID: 17069850
Negative regulation of Akt activity by p38alpha MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1.
Zuluaga S, Alvarez-Barrientos A, Gutiérrez-Uzquiza A, Benito M, Nebreda AR, Porras A
Cell Signal. 2007
PubMed ID: 16844343
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.
Wang XM, Zhang Y, Kim HP, Zhou Z, Feghali-Bostwick CA, Liu F, Ifedigbo E, Xu X, Oury TD, Kaminski N, Choi AM
J Exp Med. 2006
PubMed ID: 17178917
The shedding activity of ADAM17 is sequestered in lipid rafts.
Tellier E, Canault M, Rebsomen L, Bonardo B, Juhan-Vague I, Nalbone G, Peiretti F
Exp Cell Res. 2006
PubMed ID: 17010968
Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy.
Krenek P, Klimas J, Kroslakova M, Gazova A, Plandorova J, Kucerova D, Fecenkova A, Svec P, Kyselovic J
Can J Physiol Pharmacol. 2006
PubMed ID: 17487232
Expression of caveolin-1 in rat Leydig cells.
Casanova MB, Lustig L, Diaz ES, Pellizzari EH, Cigorraga SB, Denduchis B
Biocell. 2006
PubMed ID: 17375463
Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1.
Shakirova Y, Bonnevier J, Albinsson S, Adner M, Rippe B, Broman J, Arner A, Swärd K
Am J Physiol Cell Physiol. 2006
PubMed ID: 17102036
Caveolin-1-deficient mice show defects in innate immunity and inflammatory immune response during Salmonella enterica serovar Typhimurium infection.
Medina FA, de Almeida CJ, Dew E, Li J, Bonuccelli G, Williams TM, Cohen AW, Pestell RG, Frank PG, Tanowitz HB, Lisanti MP
Infect Immun. 2006
PubMed ID: 16982844
Albumin-bound paclitaxel, ABI-007 may show better efficacy than paclitaxel in basal-like breast cancers: association between caveolin-1 expression and ABI-007.
Altundag K, Bulut N, Dizdar O, Harputluoglu H
Breast Cancer Res Treat. 2006
PubMed ID: 16897435
Caveolin-1 knockout alters beta-adrenoceptors function in mouse small intestine.
El-Yazbi AF, Cho WJ, Schulz R, Daniel EE
Am J Physiol Gastrointest Liver Physiol. 2006
PubMed ID: 16782699
Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers.
Sotgia F, Rui H, Bonuccelli G, Mercier I, Pestell RG, Lisanti MP
Cancer Res. 2006
PubMed ID: 17108100
Caveolin-1 up-regulates IGF-I receptor gene transcription in breast cancer cells via Sp1- and p53-dependent pathways.
Glait C, Tencer L, Ravid D, Sarfstein R, Liscovitch M, Werner H
Exp Cell Res. 2006
PubMed ID: 17014845
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
Williams TM, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, Capozza F, Mercier I, Rui H, Pestell RG, Lisanti MP
Am J Pathol. 2006
PubMed ID: 17071600
Caveolin-1 in meningiomas: expression and clinico-pathological correlations.
Barresi V, Cerasoli S, Paioli G, Vitarelli E, Giuffrè G, Guiducci G, Tuccari G, Barresi G
Acta Neuropathol. 2006
PubMed ID: 16850311
Lack of evidence for caveolin-1 and CD147 interaction before and after bleomycin-induced lung injury.
Barth K, Bläsche R, Kasper M
Histochem Cell Biol. 2006
PubMed ID: 16733664
Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.
Tirado OM, Mateo-Lozano S, Villar J, Dettin LE, Llort A, Gallego S, Ban J, Kovar H, Notario V
Cancer Res. 2006
PubMed ID: 17047056
Regulation of insulin response in skeletal muscle cell by caveolin status.
Oh YS, Cho KA, Ryu SJ, Khil LY, Jun HS, Yoon JW, Park SC
J Cell Biochem. 2006
PubMed ID: 16676355
Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells.
Glait C, Ravid D, Lee SW, Liscovitch M, Werner H
FEBS Lett. 2006
PubMed ID: 16979166
Regulation of growth plate chondrocytes by 1,25-dihydroxyvitamin D3 requires caveolae and caveolin-1.
Boyan BD, Wong KL, Wang L, Yao H, Guldberg RE, Drab M, Jo H, Schwartz Z
J Bone Miner Res. 2006
PubMed ID: 16995819
Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide.
Garrean S, Gao XP, Brovkovych V, Shimizu J, Zhao YY, Vogel SM, Malik AB
J Immunol. 2006
PubMed ID: 16982927
Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells.
Kwiatek AM, Minshall RD, Cool DR, Skidgel RA, Malik AB, Tiruppathi C
Mol Pharmacol. 2006
PubMed ID: 16822931
A functional interaction between sprouty proteins and caveolin-1.
Cabrita MA, Jäggi F, Widjaja SP, Christofori G
J Biol Chem. 2006
PubMed ID: 16877379
Caveolin-1 is essential for liver regeneration.
Fernández MA, Albor C, Ingelmo-Torres M, Nixon SJ, Ferguson C, Kurzchalia T, Tebar F, Enrich C, Parton RG, Pol A
Science. 2006
PubMed ID: 16973879
Neurological abnormalities in caveolin-1 knock out mice.
Trushina E, Du Charme J, Parisi J, McMurray CT
Behav Brain Res. 2006
PubMed ID: 16750274
Increased expression of caveolin-1 and -2 in the hearts of Lewis rats with experimental autoimmune myocarditis.
Ahn M, Kim H, Matsumoto Y, Shin T
Autoimmunity. 2006
PubMed ID: 17060028
Interaction of deleted in liver cancer 1 with tensin2 in caveolae and implications in tumor suppression.
Yam JW, Ko FC, Chan CY, Jin DY, Ng IO
Cancer Res. 2006
PubMed ID: 16951145
Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN.
Schilling K, Opitz N, Wiesenthal A, Oess S, Tikkanen R, Müller-Esterl W, Icking A
Mol Biol Cell. 2006
PubMed ID: 16807357
Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA).
Wu SL, Kim J, Bandle RW, Liotta L, Petricoin E, Karger BL
Mol Cell Proteomics. 2006
PubMed ID: 16799092
Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle.
Gosens R, Stelmack GL, Dueck G, McNeill KD, Yamasaki A, Gerthoffer WT, Unruh H, Gounni AS, Zaagsma J, Halayko AJ
Am J Physiol Lung Cell Mol Physiol. 2006
PubMed ID: 16617096
Caveolin-1 expression is associated with a basal-like phenotype in sporadic and hereditary breast cancer.
Pinilla SM, Honrado E, Hardisson D, Benítez J, Palacios J
Breast Cancer Res Treat. 2006
PubMed ID: 16541313
Transvascular protein transport in mice lacking endothelial caveolae.
Rosengren BI, Rippe A, Rippe C, Venturoli D, Swärd K, Rippe B
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16501011
Integrin-mediated adhesion regulates membrane order.
Gaus K, Le Lay S, Balasubramanian N, Schwartz MA
J Cell Biol. 2006
PubMed ID: 16943184
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin.
Yamamoto H, Komekado H, Kikuchi A
Dev Cell. 2006
PubMed ID: 16890161
Genetic analysis of caveolin-1 and eNOS genes in colorectal cancer.
Conde MC, Ramirez-Lorca R, Lopez-Jamar JM, Molero E, Ramírez-Armengol JA, Moreno Nogueira JA, Pascual MH, Ruiz A, Martín-Cordova CG, Real LM, Royo JL
Oncol Rep. 2006
PubMed ID: 16820915
Caveolin-1 and regulation of cellular cholesterol homeostasis.
Frank PG, Cheung MW, Pavlides S, Llaverias G, Park DS, Lisanti MP
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16603689
Regional myocardial ischemia-induced activation of MAPKs is associated with subcellular redistribution of caveolin and cholesterol.
Ballard-Croft C, Locklar AC, Kristo G, Lasley RD
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16565301
Caveolin-1 immuno-expression in human fetal tissues during mid and late gestation.
Barresi V, Grosso M, Bulfamante G, Vitarelli E, Ghioni MC, Barresi G
Eur J Histochem. 2006
PubMed ID: 16920641
Association of prostate-specific membrane antigen with caveolin-1 and its caveolae-dependent internalization in microvascular endothelial cells: implications for targeting to tumor vasculature.
Anilkumar G, Barwe SP, Christiansen JJ, Rajasekaran SA, Kohn DB, Rajasekaran AK
Microvasc Res. 2006
PubMed ID: 16713605
Protein kinase C-mediated endothelial barrier regulation is caveolin-1-dependent.
Waschke J, Golenhofen N, Kurzchalia TV, Drenckhahn D
Histochem Cell Biol. 2006
PubMed ID: 16416023
Divergent expression and roles for caveolin-1 in mouse hepatocarcinoma cell lines with varying invasive ability.
Zhou H, Jia L, Wang S, Wang H, Chu H, Hu Y, Cao J, Zhang J
Biochem Biophys Res Commun. 2006
PubMed ID: 16684506
Focal adhesions in (myo)fibroblasts scaffold adenylyl cyclase with phosphorylated caveolin.
Swaney JS, Patel HH, Yokoyama U, Head BP, Roth DM, Insel PA
J Biol Chem. 2006
PubMed ID: 16618703
Subcellular targeting and trafficking of nitric oxide synthases.
Oess S, Icking A, Fulton D, Govers R, Müller-Esterl W
Biochem J. 2006
PubMed ID: 16722822
Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.
Li T, Sotgia F, Vuolo MA, Li M, Yang WC, Pestell RG, Sparano JA, Lisanti MP
Am J Pathol. 2006
PubMed ID: 16723714
Immunohistochemical study of caveolin-1 and -2 in the rat retina.
Kim H, Lee T, Lee J, Ahn M, Moon C, Wie MB, Shin T
J Vet Sci. 2006
PubMed ID: 16645331
DHCR24-knockout embryonic fibroblasts are susceptible to serum withdrawal-induced apoptosis because of dysfunction of caveolae and insulin-Akt-Bad signaling.
Lu X, Kambe F, Cao X, Yoshida T, Ohmori S, Murakami K, Kaji T, Ishii T, Zadworny D, Seo H
Endocrinology. 2006
PubMed ID: 16513830
Genetic ablation of caveolin-1 modifies Ca2+ spark coupling in murine arterial smooth muscle cells.
Cheng X, Jaggar JH
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16428350
Caveolin-1-deficient aortic smooth muscle cells show cell autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction.
Hassan GS, Williams TM, Frank PG, Lisanti MP
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16415072
Caveolin-1 inhibits neurite growth by blocking Rac1/Cdc42 and p21-activated kinase 1 interactions.
Kang MJ, Seo JS, Park WY
Neuroreport. 2006
PubMed ID: 16708022
Epidermal growth factor receptor exposed to oxidative stress undergoes Src- and caveolin-1-dependent perinuclear trafficking.
Khan EM, Heidinger JM, Levy M, Lisanti MP, Ravid T, Goldkorn T
J Biol Chem. 2006
PubMed ID: 16407214
Caveolin plays a central role in endothelial progenitor cell mobilization and homing in SDF-1-driven postischemic vasculogenesis.
Sbaa E, Dewever J, Martinive P, Bouzin C, Frérart F, Balligand JL, Dessy C, Feron O
Circ Res. 2006
PubMed ID: 16601228
Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels.
Yu J, Bergaya S, Murata T, Alp IF, Bauer MP, Lin MI, Drab M, Kurzchalia TV, Stan RV, Sessa WC
J Clin Invest. 2006
PubMed ID: 16670769
Role of caveolin-1 in the regulation of the vascular shear stress response.
Frank PG, Lisanti MP
J Clin Invest. 2006
PubMed ID: 16670766
Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin.
Torres VA, Tapia JC, Rodríguez DA, Párraga M, Lisboa P, Montoya M, Leyton L, Quest AF
J Cell Sci. 2006
PubMed ID: 16608879
Caveolae and cell swelling. Focus on "Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells".
Martin S
Am J Physiol Cell Physiol. 2006
PubMed ID: 16601146
Hexose transporters GLUT1 and GLUT3 are colocalized with hexokinase I in caveolae microdomains of rat spermatogenic cells.
Rauch MC, Ocampo ME, Bohle J, Amthauer R, Yáñez AJ, Rodríguez-Gil JE, Slebe JC, Reyes JG, Concha II
J Cell Physiol. 2006
PubMed ID: 16419038
Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells.
Ullrich N, Caplanusi A, Brône B, Hermans D, Larivière E, Nilius B, Van Driessche W, Eggermont J
Am J Physiol Cell Physiol. 2006
PubMed ID: 16338968
Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing.
Kang MJ, Chung YH, Hwang CI, Murata M, Fujimoto T, Mook-Jung IH, Cha CI, Park WY
Exp Mol Med. 2006
PubMed ID: 16672766
Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells: role of 5-HT2A receptors, caveolin-1, and KV1.5 channel internalization.
Cogolludo A, Moreno L, Lodi F, Frazziano G, Cobeño L, Tamargo J, Perez-Vizcaino F
Circ Res. 2006
PubMed ID: 16527989
Caveolin-1 is required for fatty acid translocase (FAT/CD36) localization and function at the plasma membrane of mouse embryonic fibroblasts.
Ring A, Le Lay S, Pohl J, Verkade P, Stremmel W
Biochim Biophys Acta. 2006
PubMed ID: 16702023
Genetic analysis of CAV1 gene in hypertension and metabolic syndrome.
Grilo A, Fernandez ML, Beltrán M, Ramirez-Lorca R, González MA, Royo JL, Gutierrez-Tous R, Morón FJ, Couto C, Serrano-Rios M, Saez ME, Ruiz A, Real LM
Thromb Haemost. 2006
PubMed ID: 16601841
Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway.
Wang XM, Kim HP, Song R, Choi AM
Am J Respir Cell Mol Biol. 2006
PubMed ID: 16357362
Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues.
Kim HA, Kim KH, Lee RA
Exp Mol Pathol. 2006
PubMed ID: 16202996
Caveolin regulates microtubule polymerization in the vascular smooth muscle cells.
Kawabe J, Okumura S, Nathanson MA, Hasebe N, Ishikawa Y
Biochem Biophys Res Commun. 2006
PubMed ID: 16480946
The rotavirus enterotoxin NSP4 directly interacts with the caveolar structural protein caveolin-1.
Parr RD, Storey SM, Mitchell DM, McIntosh AL, Zhou M, Mir KD, Ball JM
J Virol. 2006
PubMed ID: 16501093
Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyper-activates STAT5a signaling.
Sotgia F, Schubert W, Pestell RG, Lisanti MP
Cancer Biol Ther. 2006
PubMed ID: 16418573
Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt.
Boyanapalli M, Lahoud OB, Messiaen L, Kim B, Anderle de Sylor MS, Duckett SJ, Somara S, Mikol DD
Biochem Biophys Res Commun. 2006
PubMed ID: 16405917
Epithelial growth factor-induced phosphorylation of caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells.
Orlichenko L, Huang B, Krueger E, McNiven MA
J Biol Chem. 2006
PubMed ID: 16332692
Disruption of caveolin-1 leads to enhanced nitrosative stress and severe systolic and diastolic heart failure.
Wunderlich C, Schober K, Lange SA, Drab M, Braun-Dullaeus RC, Kasper M, Schwencke C, Schmeisser A, Strasser RH
Biochem Biophys Res Commun. 2006
PubMed ID: 16380094
Nitric oxide down-regulates caveolin-1 expression in rat brains during focal cerebral ischemia and reperfusion injury.
Shen J, Ma S, Chan P, Lee W, Fung PC, Cheung RT, Tong Y, Liu KJ
J Neurochem. 2006
PubMed ID: 16417587
Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting.
Perret-Vivancos C, Abbate A, Ardail D, Raccurt M, Usson Y, Lobie PE, Morel G
Exp Cell Res. 2006
PubMed ID: 16352305
Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer.
Van den Eynden GG, Van Laere SJ, Van der Auwera I, Merajver SD, Van Marck EA, van Dam P, Vermeulen PB, Dirix LY, van Golen KL
Breast Cancer Res Treat. 2006
PubMed ID: 16244790
siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway.
Miyawaki-Shimizu K, Predescu D, Shimizu J, Broman M, Predescu S, Malik AB
Am J Physiol Lung Cell Mol Physiol. 2006
PubMed ID: 16183667
Impact of caveolin-1 knockout on NANC relaxation in circular muscles of the mouse small intestine compared with longitudinal muscles.
El-Yazbi AF, Cho WJ, Boddy G, Schulz R, Daniel EE
Am J Physiol Gastrointest Liver Physiol. 2006
PubMed ID: 16166342
Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha.
Barros RP, Machado UF, Warner M, Gustafsson JA
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16423895
Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma.
Hirasawa Y, Arai M, Imazeki F, Tada M, Mikata R, Fukai K, Miyazaki M, Ochiai T, Saisho H, Yokosuka O
Oncology. 2006
PubMed ID: 17341888
Caveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSM.
Krasteva G, Pfeil U, Drab M, Kummer W, König P
Respir Res. 2006
PubMed ID: 16904002
Caveolin-1 inhibits anoikis and promotes survival signaling in cancer cells.
Ravid D, Maor S, Werner H, Liscovitch M
Adv Enzyme Regul. 2006
PubMed ID: 16857240
Caveolin-1 is associated with VCAM-1 dependent adhesion of gastric cancer cells to endothelial cells.
Shin J, Kim J, Ryu B, Chi SG, Park H
Cell Physiol Biochem. 2006
PubMed ID: 16790997
Caveolin-1 up-regulates CD147 glycosylation and the invasive capability of murine hepatocarcinoma cell lines.
Jia L, Wang S, Zhou H, Cao J, Hu Y, Zhang J
Int J Biochem Cell Biol. 2006
PubMed ID: 16702020
Opposite effect of caveolin-1 in the metabolism of high-density and low-density lipoproteins.
Truong TQ, Aubin D, Bourgeois P, Falstrault L, Brissette L
Biochim Biophys Acta. 2006
PubMed ID: 16443388
Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.
Sotgia F, Williams TM, Schubert W, Medina F, Minetti C, Pestell RG, Lisanti MP
Am J Pathol. 2006
PubMed ID: 16400031
The LIFEdb database in 2006.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S
Nucleic Acids Res. 2006
PubMed ID: 16381901
The potential role of caveolin-1 in inhibition of aquaporins during the AVD.
Jablonski EM, Hughes FM
Biol Cell. 2006
PubMed ID: 16354160
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
Transitional cell carcinomas and nonurothelial carcinomas of the urinary bladder differ in the promoter methylation status of the caveolin-1, hDAB2IP and p53 genes, but not in the global methylation of Alu elements.
Kunze E, Von Bonin F, Werner C, Wendt M, Schlott T
Int J Mol Med. 2006
PubMed ID: 16328005
Cyclin and caveolin expression in an acute model of murine Chagasic myocarditis.
Nagajyothi F, Desruisseaux M, Bouzahzah B, Weiss LM, Andrade Ddos S, Factor SM, Scherer PE, Albanese C, Lisanti MP, Tanowitz HB
Cell Cycle. 2006
PubMed ID: 16319533
Getting rid of caveolins: phenotypes of caveolin-deficient animals.
Le Lay S, Kurzchalia TV
Biochim Biophys Acta. 2005
PubMed ID: 16019085
Structural insights into the function of human caveolin 1.
Spisni E, Tomasi V, Cestaro A, Tosatto SC
Biochem Biophys Res Commun. 2005
PubMed ID: 16263077
Oestrogen-mediated tyrosine phosphorylation of caveolin-1 and its effect on the oestrogen receptor localisation: an in vivo study.
Kiss AL, Turi A, Müllner N, Kovács E, Botos E, Greger A
Mol Cell Endocrinol. 2005
PubMed ID: 16368181
Caveolin-1 is down-regulated and inversely correlated with HER2 and EGFR expression status in invasive ductal carcinoma of the breast.
Park SS, Kim JE, Kim YA, Kim YC, Kim SW
Histopathology. 2005
PubMed ID: 16324201
Regulation of cellular caveolin-1 protein expression in murine macrophages by microbial products.
Lei MG, Tan X, Qureshi N, Morrison DC
Infect Immun. 2005
PubMed ID: 16299308
Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation.
Li J, Hassan GS, Williams TM, Minetti C, Pestell RG, Tanowitz HB, Frank PG, Sotgia F, Lisanti MP
Cell Cycle. 2005
PubMed ID: 16294037
Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling.
Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP
Cell Cycle. 2005
PubMed ID: 16294019
Reverse cholesterol transport and cholesterol efflux in atherosclerosis.
Ohashi R, Mu H, Wang X, Yao Q, Chen C
QJM. 2005
PubMed ID: 16258026
Insulin and IGF-I phosphorylate eNOS in HUVECs by a caveolin-1 dependent mechanism.
Repetto S, Salani B, Maggi D, Cordera R
Biochem Biophys Res Commun. 2005
PubMed ID: 16225848
Oligodendrocyte-myelin glycoprotein is present in lipid rafts and caveolin-1-enriched membranes.
Boyanapalli M, Kottis V, Lahoud O, Bamri-Ezzine S, Braun PE, Mikol DD
Glia. 2005
PubMed ID: 15968633
Caveolin-1 is not essential for biosynthetic apical membrane transport.
Manninen A, Verkade P, Le Lay S, Torkko J, Kasper M, Füllekrug J, Simons K
Mol Cell Biol. 2005
PubMed ID: 16260622
Simultaneous expression of caveolin-1 and E-cadherin in ovarian carcinoma cells stabilizes adherens junctions through inhibition of src-related kinases.
Miotti S, Tomassetti A, Facetti I, Sanna E, Berno V, Canevari S
Am J Pathol. 2005
PubMed ID: 16251425
Comparative effect of fish oil feeding and other dietary fatty acids on plasma lipoproteins, biliary lipids, and hepatic expression of proteins involved in reverse cholesterol transport in the rat.
Morgado N, Rigotti A, Valenzuela A
Ann Nutr Metab. 2005
PubMed ID: 16227687
Impaired phagocytosis in caveolin-1 deficient macrophages.
Li J, Scherl A, Medina F, Frank PG, Kitsis RN, Tanowitz HB, Sotgia F, Lisanti MP
Cell Cycle. 2005
PubMed ID: 16205123
Tyrosine phosphorylation of caveolin 1 by oxidative stress is reversible and dependent on the c-src tyrosine kinase but not mitogen-activated protein kinase pathways in placental artery endothelial cells.
Chen DB, Li SM, Qian XX, Moon C, Zheng J
Biol Reprod. 2005
PubMed ID: 15958730
Association of a CAV-1 haplotype to familial aggressive prostate cancer.
Haeusler J, Hoegel J, Bachmann N, Herkommer K, Paiss T, Vogel W, Maier C
Prostate. 2005
PubMed ID: 15948133
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
The Sprouty-related protein, Spred-1, localizes in a lipid raft/caveola and inhibits ERK activation in collaboration with caveolin-1.
Nonami A, Taketomi T, Kimura A, Saeki K, Takaki H, Sanada T, Taniguchi K, Harada M, Kato R, Yoshimura A
Genes Cells. 2005
PubMed ID: 16115197
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.
del Pozo MA, Balasubramanian N, Alderson NB, Kiosses WB, Grande-García A, Anderson RG, Schwartz MA
Nat Cell Biol. 2005
PubMed ID: 16113676
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.
Zhang Y, Wolf-Yadlin A, Ross PL, Pappin DJ, Rush J, Lauffenburger DA, White FM
Mol Cell Proteomics. 2005
PubMed ID: 15951569
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide.
Kim HP, Wang X, Nakao A, Kim SI, Murase N, Choi ME, Ryter SW, Choi AM
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16051704
Caveolin-1 gene knockout impairs nitrergic function in mouse small intestine.
El-Yazbi AF, Cho WJ, Boddy G, Daniel EE
Br J Pharmacol. 2005
PubMed ID: 15937515
Expression of caveolin-1, -2, and -3 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis.
Shin T, Kim H, Jin JK, Moon C, Ahn M, Tanuma N, Matsumoto Y
J Neuroimmunol. 2005
PubMed ID: 15925413
Ceramide displaces cholesterol from lipid rafts and decreases the association of the cholesterol binding protein caveolin-1.
Yu C, Alterman M, Dobrowsky RT
J Lipid Res. 2005
PubMed ID: 15863835
Caveolin-1 is not required for murine intestinal cholesterol transport.
Valasek MA, Weng J, Shaul PW, Anderson RG, Repa JJ
J Biol Chem. 2005
PubMed ID: 15919660
Cellular localization and interaction of ABCA1 and caveolin-1 in aortic endothelial cells after HDL incubation.
Chao WT, Tsai SH, Lin YC, Lin WW, Yang VC
Biochem Biophys Res Commun. 2005
PubMed ID: 15907796
High-fat feeding period affects gene expression in rat white adipose tissue.
Lopez IP, Milagro FI, Marti A, Moreno-Aliaga MJ, Martinez JA, De Miguel C
Mol Cell Biochem. 2005
PubMed ID: 16335790
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.
Williams TM, Hassan GS, Li J, Cohen AW, Medina F, Frank PG, Pestell RG, Di Vizio D, Loda M, Lisanti MP
J Biol Chem. 2005
PubMed ID: 15802273
Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current.
Brainard AM, Miller AJ, Martens JR, England SK
Am J Physiol Cell Physiol. 2005
PubMed ID: 15703204
High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis.
Yokomori H, Oda M, Wakabayashi G, Kitajima M, Yoshimura K, Nomura M, Hibi T
World J Gastroenterol. 2005
PubMed ID: 15968725
Caveolin-1 enhances tissue factor pathway inhibitor exposure and function on the cell surface.
Lupu C, Hu X, Lupu F
J Biol Chem. 2005
PubMed ID: 15817451
The subcellular localization control of integrin linked kinase 1 through its protein-protein interaction with caveolin-1.
Chun J, Hyun S, Kwon T, Lee EJ, Hong SK, Kang SS
Cell Signal. 2005
PubMed ID: 15722199
Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells.
Park JS, Kim HY, Kim HW, Chae GN, Oh HT, Park JY, Shim H, Seo M, Shin EY, Kim EG, Park SC, Kwak SJ
Mech Ageing Dev. 2005
PubMed ID: 15811424
Decline in caveolin-1 expression and scaffolding of G protein receptor kinase-2 with age in Fischer 344 aortic vascular smooth muscle.
Schutzer WE, Reed JF, Mader SL
Am J Physiol Heart Circ Physiol. 2005
PubMed ID: 15626685
Dissociation of insulin receptor expression and signaling from caveolin-1 expression.
Wharton J, Meshulam T, Vallega G, Pilch P
J Biol Chem. 2005
PubMed ID: 15699039
Opposing effects of protein kinase Calpha and protein kinase Cepsilon on collagen expression by human lung fibroblasts are mediated via MEK/ERK and caveolin-1 signaling.
Tourkina E, Gooz P, Pannu J, Bonner M, Scholz D, Hacker S, Silver RM, Trojanowska M, Hoffman S
J Biol Chem. 2005
PubMed ID: 15691837
Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells.
Suchanek M, Radzikowska A, Thiele C
Nat Methods. 2005
PubMed ID: 15782218
Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells.
Cavallo-Medved D, Mai J, Dosescu J, Sameni M, Sloane BF
J Cell Sci. 2005
PubMed ID: 15769846
ACTH-induced caveolin-1 tyrosine phosphorylation is related to podosome assembly in Y1 adrenal cells.
Colonna C, Podestá EJ
Exp Cell Res. 2005
PubMed ID: 15748889
Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo.
Sedding DG, Hermsen J, Seay U, Eickelberg O, Kummer W, Schwencke C, Strasser RH, Tillmanns H, Braun-Dullaeus RC
Circ Res. 2005
PubMed ID: 15731459
Expression of caveolin-1 in lymphocytes induces caveolae formation and recruitment of phosphofructokinase to the plasma membrane.
Vallejo J, Hardin CD
FASEB J. 2005
PubMed ID: 15665033
PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.
Cairo S, De Falco F, Pizzo M, Salomoni P, Pandolfi PP, Meroni G
Oncogene. 2005
PubMed ID: 15735755
Nuclear localizing anti-DNA antibodies enter cells via caveoli and modulate expression of caveolin and p53.
Yanase K, Madaio MP
J Autoimmun. 2005
PubMed ID: 15829407
Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue.
Cohen AW, Schubert W, Brasaemle DL, Scherer PE, Lisanti MP
Diabetes. 2005
PubMed ID: 15734843
Intracellular retention of caveolin 1 in presenilin-deficient cells.
Wood DR, Nye JS, Lamb NJ, Fernandez A, Kitzmann M
J Biol Chem. 2005
PubMed ID: 15613480
Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.
Ravid D, Maor S, Werner H, Liscovitch M
Oncogene. 2005
PubMed ID: 15592498
Loss of caveolin-1 polarity impedes endothelial cell polarization and directional movement.
Beardsley A, Fang K, Mertz H, Castranova V, Friend S, Liu J
J Biol Chem. 2005
PubMed ID: 15504729
Met proto-oncogene juxtamembrane rare variations in mouse and humans: differential effects of Arg and Cys alleles on mouse lung tumorigenesis.
Zaffaroni D, Spinola M, Galvan A, Falvella FS, Pazzaglia S, Saran A, Mancuso MT, Galbiati F, Pignatiello C, Cabrera W, Ibanez O, Manenti G, Dragani TA
Oncogene. 2005
PubMed ID: 15592501
A role for caveolin-1 in post-injury reactive neuronal plasticity.
Gaudreault SB, Blain JF, Gratton JP, Poirier J
J Neurochem. 2005
PubMed ID: 15686485
Dynamics and interaction of caveolin-1 isoforms with BMP-receptors.
Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO
J Cell Sci. 2005
PubMed ID: 15657086
Developmental regulation of PV-1 in rat lung: association with the nuclear envelope and limited colocalization with Cav-1.
Hnasko R, Ben-Jonathan N
Am J Physiol Lung Cell Mol Physiol. 2005
PubMed ID: 15640522
Fibronectin matrix turnover occurs through a caveolin-1-dependent process.
Sottile J, Chandler J
Mol Biol Cell. 2005
PubMed ID: 15563605
Direct control of caveolin-1 expression by FOXO transcription factors.
van den Heuvel AP, Schulze A, Burgering BM
Biochem J. 2005
PubMed ID: 15458387
KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling.
Cao S, Fernandez-Zapico ME, Jin D, Puri V, Cook TA, Lerman LO, Zhu XY, Urrutia R, Shah V
J Biol Chem. 2005
PubMed ID: 15531587
Caveolin and GLT-1 gene expression is reciprocally regulated in primary astrocytes: association of GLT-1 with non-caveolar lipid rafts.
Zschocke J, Bayatti N, Behl C
Glia. 2005
PubMed ID: 15494979
Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1.
Lin M, DiVito MM, Merajver SD, Boyanapalli M, van Golen KL
Mol Cancer. 2005
PubMed ID: 15969750
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ
Nat Biotechnol. 2005
PubMed ID: 15592455
Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase.
Labrecque L, Nyalendo C, Langlois S, Durocher Y, Roghi C, Murphy G, Gingras D, Béliveau R
J Biol Chem. 2004
PubMed ID: 15466865
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.
Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP
J Biol Chem. 2004
PubMed ID: 15355971
Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts.
Shalom-Barak T, Nicholas JM, Wang Y, Zhang X, Ong ES, Young TH, Gendler SJ, Evans RM, Barak Y
Mol Cell Biol. 2004
PubMed ID: 15572671
Loss of caveolin-1 expression is associated with disruption of muscarinic cholinergic activities in the urinary bladder.
Lai HH, Boone TB, Yang G, Smith CP, Kiss S, Thompson TC, Somogyi GT
Neurochem Int. 2004
PubMed ID: 15380628
Functional form of Caveolin-1 is necessary for the assembly of alpha-hemolysin.
Vijayvargia R, Suresh CG, Krishnasastry MV
Biochem Biophys Res Commun. 2004
PubMed ID: 15485672
Assembly of alpha-hemolysin on A431 cells leads to clustering of Caveolin-1.
Vijayvargia R, Kaur S, Sangha N, Sahasrabuddhe AA, Surolia I, Shouche Y, Krishnasastry MV
Biochem Biophys Res Commun. 2004
PubMed ID: 15485671
Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels.
Sampson LJ, Hayabuchi Y, Standen NB, Dart C
Circ Res. 2004
PubMed ID: 15499025
Effects of chronic renal failure on caveolin-1, guanylate cyclase and AKT protein expression.
Sindhu RK, Ehdaie A, Vaziri ND, Roberts CK
Biochim Biophys Acta. 2004
PubMed ID: 15511630
The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection.
Hovanessian AG, Briand JP, Said EA, Svab J, Ferris S, Dali H, Muller S, Desgranges C, Krust B
Immunity. 2004
PubMed ID: 15539149
Prion replication alters the distribution of synaptophysin and caveolin 1 in neuronal lipid rafts.
Russelakis-Carneiro M, Hetz C, Maundrell K, Soto C
Am J Pathol. 2004
PubMed ID: 15509552
Caveolin-1 in mesangial cells suppresses MAP kinase activation and cell proliferation induced by bFGF and PDGF.
Fujita Y, Maruyama S, Kogo H, Matsuo S, Fujimoto T
Kidney Int. 2004
PubMed ID: 15496150
Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism.
Llaverias G, Vázquez-Carrera M, Sánchez RM, Noé V, Ciudad CJ, Laguna JC, Alegret M
J Lipid Res. 2004
PubMed ID: 15314095
Suppression of P-glycoprotein gene expression in Hs578T/Dox by the overexpression of caveolin-1.
Zhu H, Cai C, Chen J
FEBS Lett. 2004
PubMed ID: 15498565
Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line.
Llorente A, de Marco MC, Alonso MA
J Cell Sci. 2004
PubMed ID: 15466889
Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.
Aboulaich N, Vainonen JP, Strålfors P, Vener AV
Biochem J. 2004
PubMed ID: 15242332
Caveolin-1 inhibits breast cancer growth and metastasis.
Sloan EK, Stanley KL, Anderson RL
Oncogene. 2004
PubMed ID: 15334058
Evidence for Na+/Ca2+ exchanger 1 association with caveolin-1 and -2 in C6 glioma cells.
Cha SH, Shin SY, Jung SY, Kim YT, Park YJ, Kwak JO, Kim HW, Suh CK
IUBMB Life. 2004
PubMed ID: 15814461
From ORFeome to biology: a functional genomics pipeline.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A
Genome Res. 2004
PubMed ID: 15489336
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Mutational, epigenetic and expressional analyses of caveolin-1 gene in breast cancers.
Chen ST, Lin SY, Yeh KT, Kuo SJ, Chan WL, Chu YP, Chang JG
Int J Mol Med. 2004
PubMed ID: 15375584
Conformational defects slow Golgi exit, block oligomerization, and reduce raft affinity of caveolin-1 mutant proteins.
Ren X, Ostermeyer AG, Ramcharan LT, Zeng Y, Lublin DM, Brown DA
Mol Biol Cell. 2004
PubMed ID: 15304521
Morphological adjustment of senescent cells by modulating caveolin-1 status.
Cho KA, Ryu SJ, Oh YS, Park JH, Lee JW, Kim HP, Kim KT, Jang IS, Park SC
J Biol Chem. 2004
PubMed ID: 15263006
CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1.
Ohnuma K, Yamochi T, Uchiyama M, Nishibashi K, Yoshikawa N, Shimizu N, Iwata S, Tanaka H, Dang NH, Morimoto C
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15353589
Effect of insulin on caveolin-enriched membrane domains in rat liver.
Balbis A, Baquiran G, Mounier C, Posner BI
J Biol Chem. 2004
PubMed ID: 15252027
Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension.
Mathew R, Huang J, Shah M, Patel K, Gewitz M, Sehgal PB
Circulation. 2004
PubMed ID: 15353500
Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow.
Pang A, Au WY, Kwong YL
Leuk Res. 2004
PubMed ID: 15234575
Caveolin-1 and cancer multidrug resistance: coordinate regulation of pro-survival proteins?
Shatz M, Liscovitch M
Leuk Res. 2004
PubMed ID: 15234566
Links between CD147 function, glycosylation, and caveolin-1.
Tang W, Chang SB, Hemler ME
Mol Biol Cell. 2004
PubMed ID: 15201341
Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors.
Bhatnagar A, Sheffler DJ, Kroeze WK, Compton-Toth B, Roth BL
J Biol Chem. 2004
PubMed ID: 15190056
Impact of caveolin-1 expression on clinicopathological parameters in renal cell carcinoma.
Horiguchi A, Asano T, Asakuma J, Asano T, Sumitomo M, Hayakawa M
J Urol. 2004
PubMed ID: 15247769
Overexpression of caveolin-1 increases plasma membrane fluidity and reduces P-glycoprotein function in Hs578T/Dox.
Cai C, Zhu H, Chen J
Biochem Biophys Res Commun. 2004
PubMed ID: 15240128
N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes.
Vainonen JP, Aboulaich N, Turkina MV, Strålfors P, Vener AV
Biochem Biophys Res Commun. 2004
PubMed ID: 15219854
Caveolin-1, Id3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells.
Watanabe T, Akishita M, Nakaoka T, He H, Miyahara Y, Yamashita N, Wada Y, Aburatani H, Yoshizumi M, Kozaki K, Ouchi Y
Life Sci. 2004
PubMed ID: 15219810
Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis.
Sonveaux P, Martinive P, DeWever J, Batova Z, Daneau G, Pelat M, Ghisdal P, Grégoire V, Dessy C, Balligand JL, Feron O
Circ Res. 2004
PubMed ID: 15205364
Transcription of the caveolin-1 gene is differentially regulated in lung type I epithelial and endothelial cell lines. A role for ETS proteins in epithelial cell expression.
Kathuria H, Cao YX, Ramirez MI, Williams MC
J Biol Chem. 2004
PubMed ID: 15138262
Caveolin-1 deficiency stimulates neointima formation during vascular injury.
Hassan GS, Jasmin JF, Schubert W, Frank PG, Lisanti MP
Biochemistry. 2004
PubMed ID: 15222744
Exocrine pancreatic secretion of phospholipid, menaquinone-4, and caveolin-1 in vivo.
Thomas DD, Krzykowski KJ, Engelke JA, Groblewski GE
Biochem Biophys Res Commun. 2004
PubMed ID: 15184077
Co-localization of P2Y1 receptor and NTPDase1/CD39 within caveolae in human placenta.
Kittel A, Csapó ZS, Csizmadia E, Jackson SW, Robson SC
Eur J Histochem. 2004
PubMed ID: 15590415
Caveolae compartmentalization of heme oxygenase-1 in endothelial cells.
Kim HP, Wang X, Galbiati F, Ryter SW, Choi AM
FASEB J. 2004
PubMed ID: 15226268
Contribution of caveolin-1 alpha and Akt to TNF-alpha-induced cell death.
Ono K, Iwanaga Y, Hirayama M, Kawamura T, Sowa N, Hasegawa K
Am J Physiol Lung Cell Mol Physiol. 2004
PubMed ID: 15020298
Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer.
Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, Ramirez RD, Shay JW, Gazdar AF, Minna JD
Cancer Res. 2004
PubMed ID: 15205342
Sterol carrier protein-2 directly interacts with caveolin-1 in vitro and in vivo.
Zhou M, Parr RD, Petrescu AD, Payne HR, Atshaves BP, Kier AB, Ball JM, Schroeder F
Biochemistry. 2004
PubMed ID: 15182174
Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP
J Biol Chem. 2004
PubMed ID: 15044451
Caveolae: biochemical analysis.
Chatenay-Rivauday C, Cakar ZP, Jenö P, Kuzmenko ES, Fiedler K
Mol Biol Rep. 2004
PubMed ID: 15293782
Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells.
Shajahan AN, Timblin BK, Sandoval R, Tiruppathi C, Malik AB, Minshall RD
J Biol Chem. 2004
PubMed ID: 15007081
Promoter CpG methylation of caveolin-1 in sporadic colorectal cancer.
Lin SY, Yeh KT, Chen WT, Chen HC, Chen ST, Chang JG
Anticancer Res. 2004
PubMed ID: 15274335
Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation.
Cohen AW, Razani B, Schubert W, Williams TM, Wang XB, Iyengar P, Brasaemle DL, Scherer PE, Lisanti MP
Diabetes. 2004
PubMed ID: 15111495
Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle cells.
Kawabe J, Okumura S, Lee MC, Sadoshima J, Ishikawa Y
Am J Physiol Heart Circ Physiol. 2004
PubMed ID: 15072971
Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines.
Patlolla JM, Swamy MV, Raju J, Rao CV
Oncol Rep. 2004
PubMed ID: 15069532
Nitric oxide modulates caveolin-1 and matrix metalloproteinase-9 expression and distribution at the endothelial cell/tumor cell interface.
Phillips PG, Birnby LM
Am J Physiol Lung Cell Mol Physiol. 2004
PubMed ID: 15064242
The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins.
Wadehra M, Goodglick L, Braun J
Mol Biol Cell. 2004
PubMed ID: 14978215
Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase.
Wang H, Haas M, Liang M, Cai T, Tian J, Li S, Xie Z
J Biol Chem. 2004
PubMed ID: 14963033
Expression of caveolin-1 enhances cholesterol efflux in hepatic cells.
Fu Y, Hoang A, Escher G, Parton RG, Krozowski Z, Sviridov D
J Biol Chem. 2004
PubMed ID: 14729661
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Functional caveolae are a prerequisite for CD40 signaling in human renal proximal tubule cells.
Li H, Nord EP
Am J Physiol Renal Physiol. 2004
PubMed ID: 14665433
IGF-I regulates caveolin 1 and IRS1 interaction in caveolae.
Panetta D, Biedi C, Repetto S, Cordera R, Maggi D
Biochem Biophys Res Commun. 2004
PubMed ID: 15003536
Phenotype of palmitic acid transport and of signalling in alveolar type II cells from E/H-FABP double-knockout mice: contribution of caveolin-1 and PPARgamma.
Guthmann F, Schachtrup C, Tölle A, Wissel H, Binas B, Kondo H, Owada Y, Spener F, Rüstow B
Biochim Biophys Acta. 2004
PubMed ID: 15164767
Caveolin-1 regulates matrix metalloproteinases-1 induction and CD147/EMMPRIN cell surface clustering.
Tang W, Hemler ME
J Biol Chem. 2004
PubMed ID: 14707126
Oxidative stress activates both Src-kinases and their negative regulator Csk and induces phosphorylation of two targeting proteins for Csk: caveolin-1 and paxillin.
Cao H, Sanguinetti AR, Mastick CC
Exp Cell Res. 2004
PubMed ID: 14980511
Identification of caveolin-1-interacting sites in neuronal nitric-oxide synthase. Molecular mechanism for inhibition of NO formation.
Sato Y, Sagami I, Shimizu T
J Biol Chem. 2004
PubMed ID: 14681230
Membrane-associated estrogen receptor and caveolin-1 are present in central nervous system myelin and oligodendrocyte plasma membranes.
Arvanitis DN, Wang H, Bagshaw RD, Callahan JW, Boggs JM
J Neurosci Res. 2004
PubMed ID: 14991836
Caveolin-1 knockdown by small interfering RNA suppresses responses to the chemokine monocyte chemoattractant protein-1 by human astrocytes.
Ge S, Pachter JS
J Biol Chem. 2004
PubMed ID: 14660607
Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome.
Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB
BMC Dev Biol. 2004
PubMed ID: 15005800
Mutation and aberrant expression of Caveolin-1 in human oral squamous cell carcinomas and oral cancer cell lines.
Han SE, Park KH, Lee G, Huh YJ, Min BM
Int J Oncol. 2004
PubMed ID: 14719121
Localization of low density lipoprotein receptor-related protein 1 to caveolae in 3T3-L1 adipocytes in response to insulin treatment.
Zhang H, Links PH, Ngsee JK, Tran K, Cui Z, Ko KW, Yao Z
J Biol Chem. 2004
PubMed ID: 14593097
Down-regulation of caveolin-1 in glioma vasculature: modulation by radiotherapy.
Régina A, Jodoin J, Khoueir P, Rolland Y, Berthelet F, Moumdjian R, Fenart L, Cecchelli R, Demeule M, Béliveau R
J Neurosci Res. 2004
PubMed ID: 14705150
Cellular internalization of insulin-like growth factor binding protein-3: distinct endocytic pathways facilitate re-uptake and nuclear localization.
Lee KW, Liu B, Ma L, Li H, Bang P, Koeffler HP, Cohen P
J Biol Chem. 2004
PubMed ID: 14576164
The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A2 activity.
Gaudreault SB, Chabot C, Gratton JP, Poirier J
J Biol Chem. 2004
PubMed ID: 14561756
Genetic ablation of caveolin-1 confers protection against atherosclerosis.
Frank PG, Lee H, Park DS, Tandon NN, Scherer PE, Lisanti MP
Arterioscler Thromb Vasc Biol. 2004
PubMed ID: 14563650
Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant.
Pol A, Martin S, Fernandez MA, Ferguson C, Carozzi A, Luetterforst R, Enrich C, Parton RG
Mol Biol Cell. 2004
PubMed ID: 14528016
Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.
Peng Y, Akmentin W, Connelly MA, Lund-Katz S, Phillips MC, Williams DL
Mol Biol Cell. 2004
PubMed ID: 14528013
Caveolin-1 null (-/-) mice show dramatic reductions in life span.
Park DS, Cohen AW, Frank PG, Razani B, Lee H, Williams TM, Chandra M, Shirani J, De Souza AP, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP
Biochemistry. 2003
PubMed ID: 14690422
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.
Lu Z, Ghosh S, Wang Z, Hunter T
Cancer Cell. 2003
PubMed ID: 14706341
Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation.
Zheng X, Bollinger Bollag W
J Invest Dermatol. 2003
PubMed ID: 14675200
Hepatic overexpression of caveolins increases bile salt secretion in mice.
Moreno M, Molina H, Amigo L, Zanlungo S, Arrese M, Rigotti A, Miquel JF
Hepatology. 2003
PubMed ID: 14647059
Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.
Li L, Ren CH, Tahir SA, Ren C, Thompson TC
Mol Cell Biol. 2003
PubMed ID: 14645548
A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes.
Smythe GM, Eby JC, Disatnik MH, Rando TA
J Cell Sci. 2003
PubMed ID: 14600260
Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma.
Campbell L, Gumbleton M, Griffiths DF
Br J Cancer. 2003
PubMed ID: 14612902
Fyn is required for oxidative- and hyperosmotic-stress-induced tyrosine phosphorylation of caveolin-1.
Sanguinetti AR, Cao H, Corley Mastick C
Biochem J. 2003
PubMed ID: 12921535
Caveolin-1 haploinsufficiency leads to partial transformation of human breast epithelial cells.
Zou W, McDaneld L, Smith LM
Anticancer Res. 2003
PubMed ID: 14981899
Characterization of membrane rafts isolated from rat sertoli cell cultures: caveolin and flotillin-1 content.
Evans WE, Coyer RL, Sandusky MF, Van Fleet MJ, Moore JG, Nyquist SE
J Androl. 2003
PubMed ID: 14581507
Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation.
Widberg CH, Bryant NJ, Girotti M, Rea S, James DE
J Biol Chem. 2003
PubMed ID: 12832401
Both raft- and non-raft proteins associate with CHAPS-insoluble complexes: some APP in large complexes.
Rouvinski A, Gahali-Sass I, Stav I, Metzer E, Atlan H, Taraboulos A
Biochem Biophys Res Commun. 2003
PubMed ID: 12927782
Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer.
Tahir SA, Ren C, Timme TL, Gdor Y, Hoogeveen R, Morrisett JD, Frolov A, Ayala G, Wheeler TM, Thompson TC
Clin Cancer Res. 2003
PubMed ID: 14506154
Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.
Romiti E, Meacci E, Donati C, Formigli L, Zecchi-Orlandini S, Farnararo M, Ito M, Bruni P
Arch Biochem Biophys. 2003
PubMed ID: 12921776
Mutational, epigenetic and expressional analyses of caveolin-1 gene in cervical cancers.
Chan TF, Su TH, Yeh KT, Chang JY, Lin TH, Chen JC, Yuang SS, Chang JG
Int J Oncol. 2003
PubMed ID: 12888893
Influence of caveolin on constitutively activated recombinant eNOS: insights into eNOS dysfunction in BDL rat liver.
Hendrickson H, Chatterjee S, Cao S, Morales Ruiz M, Sessa WC, Shah V
Am J Physiol Gastrointest Liver Physiol. 2003
PubMed ID: 12829439
Caveolin-1 can regulate vascular smooth muscle cell fate by switching platelet-derived growth factor signaling from a proliferative to an apoptotic pathway.
Peterson TE, Guicciardi ME, Gulati R, Kleppe LS, Mueske CS, Mookadam M, Sowa G, Gores GJ, Sessa WC, Simari RD
Arterioscler Thromb Vasc Biol. 2003
PubMed ID: 12816877
Cellular apoptosis is associated with increased caveolin-1 expression in macrophages.
Gargalovic P, Dory L
J Lipid Res. 2003
PubMed ID: 12777465
Comparative analyses of multi-species sequences from targeted genomic regions.
Thomas JW, Touchman JW, Blakesley RW, Bouffard GG, Beckstrom-Sternberg SM, Margulies EH, Blanchette M, Siepel AC, Thomas PJ, McDowell JC, Maskeri B, Hansen NF, Schwartz MS, Weber RJ, Kent WJ, Karolchik D, Bruen TC, Bevan R, Cutler DJ, Schwartz S, Elnitski L, Idol JR, Prasad AB, Lee-Lin SQ, Maduro VV, Summers TJ, Portnoy ME, Dietrich NL, Akhter N, Ayele K, Benjamin B, Cariaga K, Brinkley CP, Brooks SY, Granite S, Guan X, Gupta J, Haghighi P, Ho SL, Huang MC, Karlins E, Laric PL, Legaspi R, Lim MJ, Maduro QL, Masiello CA, Mastrian SD, McCloskey JC, Pearson R, Stantripop S, Tiongson EE, Tran JT, Tsurgeon C, Vogt JL, Walker MA, Wetherby KD, Wiggins LS, Young AC, Zhang LH, Osoegawa K, Zhu B, Zhao B, Shu CL, De Jong PJ, Lawrence CE, Smit AF, Chakravarti A, Haussler D, Green P, Miller W, Green ED
Nature. 2003
PubMed ID: 12917688
Caveolae and caveolin-1 in human term villous trophoblast.
Linton EA, Rodriguez-Linares B, Rashid-Doubell F, Ferguson DJ, Redman CW
Placenta. 2003
PubMed ID: 12852865
Senescent phenotype can be reversed by reduction of caveolin status.
Cho KA, Ryu SJ, Park JS, Jang IS, Ahn JS, Kim KT, Park SC
J Biol Chem. 2003
PubMed ID: 12730243
Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1.
Brazer SC, Singh BB, Liu X, Swaim W, Ambudkar IS
J Biol Chem. 2003
PubMed ID: 12732636
Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase III within the golgi apparatus.
Sasai K, Ikeda Y, Ihara H, Honke K, Taniguchi N
J Biol Chem. 2003
PubMed ID: 12716887
The DNA sequence of human chromosome 7.
Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S, Rohlfing T, Rock SM, Tin-Wollam AM, Abbott A, Minx P, Maupin R, Strowmatt C, Latreille P, Miller N, Johnson D, Murray J, Woessner JP, Wendl MC, Yang SP, Schultz BR, Wallis JW, Spieth J, Bieri TA, Nelson JO, Berkowicz N, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Bedell JA, Mardis ER, Clifton SW, Chissoe SL, Marra MA, Raymond C, Haugen E, Gillett W, Zhou Y, James R, Phelps K, Iadanoto S, Bubb K, Simms E, Levy R, Clendenning J, Kaul R, Kent WJ, Furey TS, Baertsch RA, Brent MR, Keibler E, Flicek P, Bork P, Suyama M, Bailey JA, Portnoy ME, Torrents D, Chinwalla AT, Gish WR, Eddy SR, McPherson JD, Olson MV, Eichler EE, Green ED, Waterston RH, Wilson RK
Nature. 2003
PubMed ID: 12853948
Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts.
Ostrom RS, Naugle JE, Hase M, Gregorian C, Swaney JS, Insel PA, Brunton LL, Meszaros JG
J Biol Chem. 2003
PubMed ID: 12711600
Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation.
Fong A, Garcia E, Gwynn L, Lisanti MP, Fazzari MJ, Li M
Am J Clin Pathol. 2003
PubMed ID: 12866378
Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue.
Cohen AW, Razani B, Wang XB, Combs TP, Williams TM, Scherer PE, Lisanti MP
Am J Physiol Cell Physiol. 2003
PubMed ID: 12660144
Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane.
Wyse BD, Prior IA, Qian H, Morrow IC, Nixon S, Muncke C, Kurzchalia TV, Thomas WG, Parton RG, Hancock JF
J Biol Chem. 2003
PubMed ID: 12692121
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
Burgermeister E, Tencer L, Liscovitch M
Oncogene. 2003
PubMed ID: 12813462
Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm.
Buttitta L, Tanaka TS, Chen AE, Ko MS, Fan CM
Dev Biol. 2003
PubMed ID: 12781685
Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli.
Woodman SE, Ashton AW, Schubert W, Lee H, Williams TM, Medina FA, Wyckoff JB, Combs TP, Lisanti MP
Am J Pathol. 2003
PubMed ID: 12759260
Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation.
Capozza F, Williams TM, Schubert W, McClain S, Bouzahzah B, Sotgia F, Lisanti MP
Am J Pathol. 2003
PubMed ID: 12759258
Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40.
Simon AM, McWhorter AR
J Cell Sci. 2003
PubMed ID: 12697838
Role of caveolae in signal-transducing function of cardiac Na+/K+-ATPase.
Liu L, Mohammadi K, Aynafshar B, Wang H, Li D, Liu J, Ivanov AV, Xie Z, Askari A
Am J Physiol Cell Physiol. 2003
PubMed ID: 12606314
The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation.
Sowa G, Pypaert M, Fulton D, Sessa WC
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12743374
Human chromosome 7: DNA sequence and biology.
Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Lai Z, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Nowaczyk MJ, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Döhner H, Döhner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui LC
Science. 2003
PubMed ID: 12690205
Caveolin expression in adult renal tumors.
Carrion R, Morgan BE, Tannenbaum M, Salup R, Morgan MB
Urol Oncol. 2003
PubMed ID: 12810205
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation.
Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C
Immunity. 2003
PubMed ID: 12753742
Caveolin-I overexpression is a favourable prognostic factor for patients with extrahepatic bile duct carcinoma.
Murakami S, Miyamoto M, Hida Y, Cho Y, Fukunaga A, Oshikiri T, Kato K, Kurokawa T, Suzuoki M, Nakakubo Y, Hiraoka K, Itoh T, Shinohara T, Morikawa T, Okushiba O, Kondo S, Katoh H
Br J Cancer. 2003
PubMed ID: 12737162
Regulated interaction of endothelin B receptor with caveolin-1.
Yamaguchi T, Murata Y, Fujiyoshi Y, Doi T
Eur J Biochem. 2003
PubMed ID: 12694195
Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis.
Cao G, Yang G, Timme TL, Saika T, Truong LD, Satoh T, Goltsov A, Park SH, Men T, Kusaka N, Tian W, Ren C, Wang H, Kadmon D, Cai WW, Chinault AC, Boone TB, Bradley A, Thompson TC
Am J Pathol. 2003
PubMed ID: 12651616
Caveolin expression and localization in human keratinocytes suggest a role in lamellar granule biogenesis.
Sando GN, Zhu H, Weis JM, Richman JT, Wertz PW, Madison KC
J Invest Dermatol. 2003
PubMed ID: 12648214
Caveolin-1 does not affect SR-BI-mediated cholesterol efflux or selective uptake of cholesteryl ester in two cell lines.
Wang L, Connelly MA, Ostermeyer AG, Chen HH, Williams DL, Brown DA
J Lipid Res. 2003
PubMed ID: 12562842
Association of the low-density lipoprotein receptor with caveolae in hamster and rat liver.
Ness GC, Kohlruss N, Gertz KR
Biochem Biophys Res Commun. 2003
PubMed ID: 12646183
The adipocyte plasma membrane caveolin functional/structural organization is necessary for the efficient endocytosis of GLUT4.
Shigematsu S, Watson RT, Khan AH, Pessin JE
J Biol Chem. 2003
PubMed ID: 12496259
Involvement of caveolin-2 in caveolar biogenesis in MDCK cells.
Lahtinen U, Honsho M, Parton RG, Simons K, Verkade P
FEBS Lett. 2003
PubMed ID: 12633858
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.
Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP
Mol Biol Cell. 2003
PubMed ID: 12631721
c-Abl is required for oxidative stress-induced phosphorylation of caveolin-1 on tyrosine 14.
Sanguinetti AR, Mastick CC
Cell Signal. 2003
PubMed ID: 12531427
Functional interaction of estrogen receptor alpha and caveolin isoforms in neuronal SK-N-MC cells.
Zschocke J, Manthey D, Bayatti N, Behl C
J Steroid Biochem Mol Biol. 2003
PubMed ID: 12711000
Endothelin-1 activates mesangial cell ERK1/2 via EGF-receptor transactivation and caveolin-1 interaction.
Hua H, Munk S, Whiteside CI
Am J Physiol Renal Physiol. 2003
PubMed ID: 12388423
Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts.
Cohen AW, Park DS, Woodman SE, Williams TM, Chandra M, Shirani J, Pereira de Souza A, Kitsis RN, Russell RG, Weiss LM, Tang B, Jelicks LA, Factor SM, Shtutin V, Tanowitz HB, Lisanti MP
Am J Physiol Cell Physiol. 2003
PubMed ID: 12388077
Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines.
Miyagawa Y, Ohguro H, Odagiri H, Maruyama I, Maeda T, Maeda A, Sasaki M, Nakazawa M
Biochem Biophys Res Commun. 2003
PubMed ID: 12507501
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.
Labrecque L, Royal I, Surprenant DS, Patterson C, Gingras D, Béliveau R
Mol Biol Cell. 2003
PubMed ID: 12529448
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Ganglioside induces caveolin-1 redistribution and interaction with the epidermal growth factor receptor.
Wang XQ, Sun P, Paller AS
J Biol Chem. 2002
PubMed ID: 12354760
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The scaffolding domain of caveolin 2 is responsible for its Golgi localization in Caco-2 cells.
Breuza L, Corby S, Arsanto JP, Delgrossi MH, Scheiffele P, Le Bivic A
J Cell Sci. 2002
PubMed ID: 12414992
Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever.
Shah M, Patel K, Fried VA, Sehgal PB
J Biol Chem. 2002
PubMed ID: 12235142
Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40.
Simon AM, McWhorter AR
Dev Biol. 2002
PubMed ID: 12435353
Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.
Murata T, Sato K, Hori M, Ozaki H, Karaki H
J Biol Chem. 2002
PubMed ID: 12185080
Localization of phospholipase D1 to caveolin-enriched membrane via palmitoylation: implications for epidermal growth factor signaling.
Han JM, Kim Y, Lee JS, Lee CS, Lee BD, Ohba M, Kuroki T, Suh PG, Ryu SH
Mol Biol Cell. 2002
PubMed ID: 12429840
Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation.
Ho CC, Huang PH, Huang HY, Chen YH, Yang PC, Hsu SM
Am J Pathol. 2002
PubMed ID: 12414512
Regulation of caveolin-1 expression and secretion by a protein kinase cepsilon signaling pathway in human prostate cancer cells.
Wu D, Terrian DM
J Biol Chem. 2002
PubMed ID: 12185081
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice.
Schubert W, Frank PG, Woodman SE, Hyogo H, Cohen DE, Chow CW, Lisanti MP
J Biol Chem. 2002
PubMed ID: 12167625
Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts.
Marchand S, Devillers-Thiéry A, Pons S, Changeux JP, Cartaud J
J Neurosci. 2002
PubMed ID: 12388596
Caveolin-1 phosphorylation in human squamous and epidermoid carcinoma cells: dependence on ErbB1 expression and Src activation.
Kim YN, Dam P, Bertics PJ
Exp Cell Res. 2002
PubMed ID: 12372346
Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade.
Woodman SE, Park DS, Cohen AW, Cheung MW, Chandra M, Shirani J, Tang B, Jelicks LA, Kitsis RN, Christ GJ, Factor SM, Tanowitz HB, Lisanti MP
J Biol Chem. 2002
PubMed ID: 12138167
Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells.
Zschocke J, Manthey D, Bayatti N, van der Burg B, Goodenough S, Behl C
J Biol Chem. 2002
PubMed ID: 12138116
Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
Park DS, Lee H, Frank PG, Razani B, Nguyen AV, Parlow AF, Russell RG, Hulit J, Pestell RG, Lisanti MP
Mol Biol Cell. 2002
PubMed ID: 12388746
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.
Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP
Am J Pathol. 2002
PubMed ID: 12368209
Endostatin associates with integrin alpha5beta1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells.
Wickström SA, Alitalo K, Keski-Oja J
Cancer Res. 2002
PubMed ID: 12359771
Extensive vascularization of developing mouse ovaries revealed by caveolin-1 expression.
Bullejos M, Bowles J, Koopman P
Dev Dyn. 2002
PubMed ID: 12203725
Blockade of human immunodeficiency virus type 1 expression by caveolin-1.
Llano M, Kelly T, Vanegas M, Peretz M, Peterson TE, Simari RD, Poeschla EM
J Virol. 2002
PubMed ID: 12186899
Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1.
Caselli A, Mazzinghi B, Camici G, Manao G, Ramponi G
Biochem Biophys Res Commun. 2002
PubMed ID: 12176037
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice.
Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J, Chien KR
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12177436
The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1.
Kimura A, Mora S, Shigematsu S, Pessin JE, Saltiel AR
J Biol Chem. 2002
PubMed ID: 12036959
Multicompartmental distribution of the tuberous sclerosis gene products, hamartin and tuberin.
Yamamoto Y, Jones KA, Mak BC, Muehlenbachs A, Yeung RS
Arch Biochem Biophys. 2002
PubMed ID: 12147258
IGF-I induces caveolin 1 tyrosine phosphorylation and translocation in the lipid rafts.
Maggi D, Biedi C, Segat D, Barbero D, Panetta D, Cordera R
Biochem Biophys Res Commun. 2002
PubMed ID: 12135605
A close association of the ganglioside-specific sialidase Neu3 with caveolin in membrane microdomains.
Wang Y, Yamaguchi K, Wada T, Hata K, Zhao X, Fujimoto T, Miyagi T
J Biol Chem. 2002
PubMed ID: 12011038
Stomatin-related olfactory protein, SRO, specifically expressed in the murine olfactory sensory neurons.
Kobayakawa K, Hayashi R, Morita K, Miyamichi K, Oka Y, Tsuboi A, Sakano H
J Neurosci. 2002
PubMed ID: 12122055
Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts.
Volonte D, Zhang K, Lisanti MP, Galbiati F
Mol Biol Cell. 2002
PubMed ID: 12134086
Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis.
Razani B, Park DS, Miyanaga Y, Ghatpande A, Cohen J, Wang XB, Scherer PE, Evans T, Lisanti MP
Biochemistry. 2002
PubMed ID: 12069580
Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.
Park DS, Woodman SE, Schubert W, Cohen AW, Frank PG, Chandra M, Shirani J, Razani B, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP
Am J Pathol. 2002
PubMed ID: 12057923
Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells.
Sotgia F, Razani B, Bonuccelli G, Schubert W, Battista M, Lee H, Capozza F, Schubert AL, Minetti C, Buckley JT, Lisanti MP
Mol Cell Biol. 2002
PubMed ID: 11997523
Connexin family members target to lipid raft domains and interact with caveolin-1.
Schubert AL, Schubert W, Spray DC, Lisanti MP
Biochemistry. 2002
PubMed ID: 11980479
The endocytosis-linked protein dynamin associates with caveolin-1 and is tyrosine phosphorylated in response to the activation of a noninternalizing epidermal growth factor receptor mutant.
Kim YN, Bertics PJ
Endocrinology. 2002
PubMed ID: 11956154
Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae.
Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H, Christ GJ, Edelmann W, Lisanti MP
Mol Cell Biol. 2002
PubMed ID: 11884617
Caveolin-1 expression enhances endothelial capillary tubule formation.
Liu J, Wang XB, Park DS, Lisanti MP
J Biol Chem. 2002
PubMed ID: 11748236
ATP dependence of the SNARE/caveolin 1 interaction in the hippocampus.
Magga JM, Kay JG, Davy A, Poulton NP, Robbins SM, Braun JE
Biochem Biophys Res Commun. 2002
PubMed ID: 11883949
A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase.
Cao H, Courchesne WE, Mastick CC
J Biol Chem. 2002
PubMed ID: 11805080
Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx.
Vargas L, Nore BF, Berglof A, Heinonen JE, Mattsson PT, Smith CI, Mohamed AJ
J Biol Chem. 2002
PubMed ID: 11751885
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities.
Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, Scherer PE, Lisanti MP
J Biol Chem. 2002
PubMed ID: 11739396
[Microdomains and caveolin]
Fujimoto T, Kogo H, Nakamura N, Ozeki S
Tanpakushitsu Kakusan Koso. 2002
PubMed ID: 11915322
Caveolin-1 expression is maintained in rat and human astroglioma cell lines.
Cameron PL, Liu C, Smart DK, Hantus ST, Fick JR, Cameron RS
Glia. 2002
PubMed ID: 11857686
Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.
Yamamoto-Katayama S, Ariyoshi M, Ishihara K, Hirano T, Jingami H, Morikawa K
J Mol Biol. 2002
PubMed ID: 11866528
Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage.
Kato K, Hida Y, Miyamoto M, Hashida H, Shinohara T, Itoh T, Okushiba S, Kondo S, Katoh H
Cancer. 2002
PubMed ID: 11920460
Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex.
Eberle HB, Serrano RL, Füllekrug J, Schlosser A, Lehmann WD, Lottspeich F, Kaloyanova D, Wieland FT, Helms JB
J Cell Sci. 2002
PubMed ID: 11865038
The expression of scavenger receptor class B, type I (SR-BI) and caveolin-1 in parenchymal and nonparenchymal liver cells.
Malerød L, Juvet K, Gjøen T, Berg T
Cell Tissue Res. 2002
PubMed ID: 11845324
Expression of caveolin-1 in human brain microvessels.
Virgintino D, Robertson D, Errede M, Benagiano V, Tauer U, Roncali L, Bertossi M
Neuroscience. 2002
PubMed ID: 12401329
The alpha-isoform of caveolin-1 is a marker of vasculogenesis in early lung development.
Ramirez MI, Pollack L, Millien G, Cao YX, Hinds A, Williams MC
J Histochem Cytochem. 2002
PubMed ID: 11748292
Caveolae-deficient endothelial cells show defects in the uptake and transport of albumin in vivo.
Schubert W, Frank PG, Razani B, Park DS, Chow CW, Lisanti MP
J Biol Chem. 2001
PubMed ID: 11689550
Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism.
Park DS, Lee H, Riedel C, Hulit J, Scherer PE, Pestell RG, Lisanti MP
J Biol Chem. 2001
PubMed ID: 11602600
Expression and localization of caveolin-1, and the presence of membrane rafts, in mouse and Guinea pig spermatozoa.
Travis AJ, Merdiushev T, Vargas LA, Jones BH, Purdon MA, Nipper RW, Galatioto J, Moss SB, Hunnicutt GR, Kopf GS
Dev Biol. 2001
PubMed ID: 11784086
Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif, PPxY, recruits SH2 domain containing proteins.
Sotgia F, Lee H, Bedford MT, Petrucci T, Sudol M, Lisanti MP
Biochemistry. 2001
PubMed ID: 11724572
In situ prostate cancer gene therapy using a novel adenoviral vector regulated by the caveolin-1 promoter.
Pramudji C, Shimura S, Ebara S, Yang G, Wang J, Ren C, Yuan Y, Tahir SA, Timme TL, Thompson TC
Clin Cancer Res. 2001
PubMed ID: 11751529
Caveolin-deficient mice: insights into caveolar function human disease.
Razani B, Lisanti MP
J Clin Invest. 2001
PubMed ID: 11733547
A dual-color FISH gene map of the proximal region of rat Chromosome 4 and comparative analysis in human and mouse.
Walentinsson A, Helou K, Levan G
Mamm Genome. 2001
PubMed ID: 11707776
Independent amplification of two gene clusters on chromosome 4 in rat endometrial cancer: identification and molecular characterization.
Walentinsson A, Helou K, Wallenius V, Hedrich HJ, Szpirer C, Levan G
Cancer Res. 2001
PubMed ID: 11719459
Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1.
Gaillard S, Bartoli M, Castets F, Monneron A
FEBS Lett. 2001
PubMed ID: 11707266
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H, Kneitz B, Lagaud G, Christ GJ, Edelmann W, Lisanti MP
J Biol Chem. 2001
PubMed ID: 11457855
Localization of neutral ceramidase in caveolin-enriched light membranes of murine endothelial cells.
Romiti E, Meacci E, Tanzi G, Becciolini L, Mitsutake S, Farnararo M, Ito M, Bruni P
FEBS Lett. 2001
PubMed ID: 11591392
Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice.
Kostka G, Giltay R, Bloch W, Addicks K, Timpl R, Fässler R, Chu ML
Mol Cell Biol. 2001
PubMed ID: 11564885
Ligand-independent activation of oestrogen receptor alpha by caveolin-1.
Schlegel A, Wang C, Pestell RG, Lisanti MP
Biochem J. 2001
PubMed ID: 11563984
Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms.
Suginta W, Karoulias N, Aitken A, Ashley RH
Biochem J. 2001
PubMed ID: 11563969
Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A.
Razani B, Lisanti MP
Am J Physiol Cell Physiol. 2001
PubMed ID: 11546661
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice.
Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV
Science. 2001
PubMed ID: 11498544
Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14).
Lee H, Woodman SE, Engelman JA, Volonté D, Galbiati F, Kaufman HL, Lublin DM, Lisanti MP
J Biol Chem. 2001
PubMed ID: 11451957
Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts.
Liou JY, Deng WG, Gilroy DW, Shyue SK, Wu KK
J Biol Chem. 2001
PubMed ID: 11432874
Caveolin-1, a putative tumour suppressor gene.
Razani B, Schlegel A, Liu J, Lisanti MP
Biochem Soc Trans. 2001
PubMed ID: 11498016
Caveolin-1 and caveolin-2 expression in mouse macrophages. High density lipoprotein 3-stimulated secretion and a lack of significant subcellular co-localization.
Gargalovic P, Dory L
J Biol Chem. 2001
PubMed ID: 11316799
Opposite pattern of MDR1 and caveolin-1 gene expression in human atherosclerotic lesions and proliferating human smooth muscle cells.
Batetta B, Mulas MF, Petruzzo P, Putzolu M, Bonatesta RR, Sanna F, Cappai A, Brotzu G, Dessì S
Cell Mol Life Sci. 2001
PubMed ID: 11529503
BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells.
de Marco MC, Kremer L, Albar JP, Martinez-Menarguez JA, Ballesta J, Garcia-Lopez MA, Marazuela M, Puertollano R, Alonso MA
J Biol Chem. 2001
PubMed ID: 11294831
The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane.
Karpen HE, Bukowski JT, Hughes T, Gratton JP, Sessa WC, Gailani MR
J Biol Chem. 2001
PubMed ID: 11278759
Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis.
Hellström M, Gerhardt H, Kalén M, Li X, Eriksson U, Wolburg H, Betsholtz C
J Cell Biol. 2001
PubMed ID: 11331305
Ovine caveolin-1: cDNA cloning, E. coli expression, and association with endothelial nitric oxide synthase.
Chen D, Zangl AL, Zhao Q, Markley JL, Zheng J, Bird IM, Magness RR
Mol Cell Endocrinol. 2001
PubMed ID: 11325515
Caveolin-1 interacts with androgen receptor. A positive modulator of androgen receptor mediated transactivation.
Lu ML, Schneider MC, Zheng Y, Zhang X, Richie JP
J Biol Chem. 2001
PubMed ID: 11278309
Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors.
Feng X, Gaeta ML, Madge LA, Yang JH, Bradley JR, Pober JS
J Biol Chem. 2001
PubMed ID: 11112773
Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor.
Razani B, Zhang XL, Bitzer M, von Gersdorff G, Böttinger EP, Lisanti MP
J Biol Chem. 2001
PubMed ID: 11102446
Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas.
Wiechen K, Sers C, Agoulnik A, Arlt K, Dietel M, Schlag PM, Schneider U
Am J Pathol. 2001
PubMed ID: 11238032
Hypermethylation of the caveolin-1 gene promoter in prostate cancer.
Cui J, Rohr LR, Swanson G, Speights VO, Maxwell T, Brothman AR
Prostate. 2001
PubMed ID: 11170154
Caveolin-1 binding to endoplasmic reticulum membranes and entry into the regulated secretory pathway are regulated by serine phosphorylation. Protein sorting at the level of the endoplasmic reticulum.
Schlegel A, Arvan P, Lisanti MP
J Biol Chem. 2001
PubMed ID: 11078729
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.
Lammert F, Carey MC, Paigen B
Gastroenterology. 2001
PubMed ID: 11208732
Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells.
Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C, Quest AF
Proc Natl Acad Sci U S A. 2000
PubMed ID: 11114180
Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within caveolin family members.
Sotgia F, Lee JK, Das K, Bedford M, Petrucci TC, Macioce P, Sargiacomo M, Bricarelli FD, Minetti C, Sudol M, Lisanti MP
J Biol Chem. 2000
PubMed ID: 10988290
Expression of truncated transient receptor potential protein 1alpha (Trp1alpha ): evidence that the Trp1 C terminus modulates store-operated Ca2+ entry.
Singh BB, Liu X, Ambudkar IS
J Biol Chem. 2000
PubMed ID: 10980191
DNA cloning using in vitro site-specific recombination.
Hartley JL, Temple GF, Brasch MA
Genome Res. 2000
PubMed ID: 11076863
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.
Lee H, Volonte D, Galbiati F, Iyengar P, Lublin DM, Bregman DB, Wilson MT, Campos-Gonzalez R, Bouzahzah B, Pestell RG, Scherer PE, Lisanti MP
Mol Endocrinol. 2000
PubMed ID: 11075810
Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction.
Igarashi J, Michel T
J Biol Chem. 2000
PubMed ID: 10921915
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
GP2, a GPI-anchored protein in the apical plasma membrane of the pancreatic acinar cell, co-immunoprecipitates with src kinases and caveolin.
Parker EM, Zaman MM, Freedman SD
Pancreas. 2000
PubMed ID: 11039464
Downmodulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor overexpression.
Bagnoli M, Tomassetti A, Figini M, Flati S, Dolo V, Canevari S, Miotti S
Oncogene. 2000
PubMed ID: 11032026
Signal transduction through prion protein.
Mouillet-Richard S, Ermonval M, Chebassier C, Laplanche JL, Lehmann S, Launay JM, Kellermann O
Science. 2000
PubMed ID: 10988071
Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S
EMBO Rep. 2000
PubMed ID: 11256614
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.
Galbiati F, Volonte D, Brown AM, Weinstein DE, Ben-Ze'ev A, Pestell RG, Lisanti MP
J Biol Chem. 2000
PubMed ID: 10816572
Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.
Gratton JP, Fontana J, O'Connor DS, Garcia-Cardena G, McCabe TJ, Sessa WC
J Biol Chem. 2000
PubMed ID: 10781589
Caveolin proteins in signaling, oncogenic transformation and muscular dystrophy.
Razani B, Schlegel A, Lisanti MP
J Cell Sci. 2000
PubMed ID: 10825283
Caveolin isoforms in resident and elicited rat peritoneal macrophages.
Kiss AL, Túri A, Müllner N, Tímár J
Eur J Cell Biol. 2000
PubMed ID: 10887965
Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments.
Garver WS, Heidenreich RA, Erickson RP, Thomas MA, Wilson JM
J Lipid Res. 2000
PubMed ID: 10787428
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
Phospholipase D2: functional interaction with caveolin in low-density membrane microdomains.
Czarny M, Fiucci G, Lavie Y, Banno Y, Nozawa Y, Liscovitch M
FEBS Lett. 2000
PubMed ID: 10675563
Caveolin-1 isoforms are encoded by distinct mRNAs. Identification Of mouse caveolin-1 mRNA variants caused by alternative transcription initiation and splicing.
Kogo H, Fujimoto T
FEBS Lett. 2000
PubMed ID: 10631317
Identification of filamin as a novel ligand for caveolin-1: evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeleton.
Stahlhut M, van Deurs B
Mol Biol Cell. 2000
PubMed ID: 10637311
Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells.
Nystrom FH, Chen H, Cong LN, Li Y, Quon MJ
Mol Endocrinol. 1999
PubMed ID: 10598578
Macrophage scavenger receptors and foam cell formation.
de Villiers WJ, Smart EJ
J Leukoc Biol. 1999
PubMed ID: 10577503
A neuronal-specific mammalian homolog of the Drosophila retinal degeneration B gene with expression restricted to the retina and dentate gyrus.
Lu C, Vihtelic TS, Hyde DR, Li T
J Neurosci. 1999
PubMed ID: 10460238
The membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for the assembly of caveolae membranes in vivo.
Das K, Lewis RY, Scherer PE, Lisanti MP
J Biol Chem. 1999
PubMed ID: 10373486
Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe.
Volonte D, Galbiati F, Li S, Nishiyama K, Okamoto T, Lisanti MP
J Biol Chem. 1999
PubMed ID: 10212252
Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines.
Engelman JA, Zhang XL, Lisanti MP
FEBS Lett. 1999
PubMed ID: 10218480
Regulation of G protein-coupled receptor kinases by caveolin.
Carman CV, Lisanti MP, Benovic JL
J Biol Chem. 1999
PubMed ID: 10085129
Phospholipase D1 in caveolae: regulation by protein kinase Calpha and caveolin-1.
Kim JH, Han JM, Lee S, Kim Y, Lee TG, Park JB, Lee SD, Suh PG, Ryu SH
Biochemistry. 1999
PubMed ID: 10090765
Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors.
Fra AM, Mastroianni N, Mancini M, Pasqualetto E, Sitia R
Genomics. 1999
PubMed ID: 10087206
Caveolin is an inhibitor of platelet-derived growth factor receptor signaling.
Yamamoto M, Toya Y, Jensen RA, Ishikawa Y
Exp Cell Res. 1999
PubMed ID: 10066366
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.
Hurlstone AF, Reid G, Reeves JR, Fraser J, Strathdee G, Rahilly M, Parkinson EK, Black DM
Oncogene. 1999
PubMed ID: 10086342
EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains.
Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R
Neuron. 1999
PubMed ID: 10197531
The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers.
Garver WS, Hossain GS, Winscott MM, Heidenreich RA
Biochim Biophys Acta. 1999
PubMed ID: 10036317
Caveolin interacts with Trk A and p75(NTR) and regulates neurotrophin signaling pathways.
Bilderback TR, Gazula VR, Lisanti MP, Dobrowsky RT
J Biol Chem. 1999
PubMed ID: 9867838
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.
Engelman JA, Zhang X, Galbiati F, Volonte D, Sotgia F, Pestell RG, Minetti C, Scherer PE, Okamoto T, Lisanti MP
Am J Hum Genet. 1998
PubMed ID: 9837809
Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers.
Engelman JA, Zhang XL, Lisanti MP
FEBS Lett. 1998
PubMed ID: 9801158
A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth.
Wary KK, Mariotti A, Zurzolo C, Giancotti FG
Cell. 1998
PubMed ID: 9741627
Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer.
Engelman JA, Lee RJ, Karnezis A, Bearss DJ, Webster M, Siegel P, Muller WJ, Windle JJ, Pestell RG, Lisanti MP
J Biol Chem. 1998
PubMed ID: 9685399
Localization of RhoA GTPase to endothelial caveolae-enriched membrane domains.
Gingras D, Gauthier F, Lamy S, Desrosiers RR, Béliveau R
Biochem Biophys Res Commun. 1998
PubMed ID: 9647788
Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31).
Engelman JA, Zhang XL, Galbiati F, Lisanti MP
FEBS Lett. 1998
PubMed ID: 9662443
Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein.
Ikezu T, Trapp BD, Song KS, Schlegel A, Lisanti MP, Okamoto T
J Biol Chem. 1998
PubMed ID: 9553108
Dynamic activation of endothelial nitric oxide synthase by Hsp90.
García-Cardeña G, Fan R, Shah V, Sorrentino R, Cirino G, Papapetropoulos A, Sessa WC
Nature. 1998
PubMed ID: 9580552
Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities.
Couet J, Sargiacomo M, Lisanti MP
J Biol Chem. 1997
PubMed ID: 9374534
Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo.
Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, van Donselaar E, Peters P, Lisanti MP
J Biol Chem. 1997
PubMed ID: 9361015
Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemann-Pick disease type C.
Garver WS, Erickson RP, Wilson JM, Colton TL, Hossain GS, Kozloski MA, Heidenreich RA
Biochim Biophys Acta. 1997
PubMed ID: 9375801
Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol.
Bist A, Fielding PE, Fielding CJ
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9380697
Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin.
Michel JB, Feron O, Sacks D, Michel T
J Biol Chem. 1997
PubMed ID: 9188442
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins.
Bickel PE, Scherer PE, Schnitzer JE, Oh P, Lisanti MP, Lodish HF
J Biol Chem. 1997
PubMed ID: 9153235
Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae.
Babitt J, Trigatti B, Rigotti A, Smart EJ, Anderson RG, Xu S, Krieger M
J Biol Chem. 1997
PubMed ID: 9148942
Large-scale concatenation cDNA sequencing.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA
Genome Res. 1997
PubMed ID: 9110174
Caveolin-3 associates with developing T-tubules during muscle differentiation.
Parton RG, Way M, Zorzi N, Stang E
J Cell Biol. 1997
PubMed ID: 9008709
Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.
Li S, Couet J, Lisanti MP
J Biol Chem. 1996
PubMed ID: 8910575
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1.
García-Cardeña G, Fan R, Stern DF, Liu J, Sessa WC
J Biol Chem. 1996
PubMed ID: 8910295
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins.
Song KS, Scherer PE, Tang Z, Okamoto T, Li S, Chafel M, Chu C, Kohtz DS, Lisanti MP
J Biol Chem. 1996
PubMed ID: 8663016
Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains.
Song KS, Li Shengwen, Okamoto T, Quilliam LA, Sargiacomo M, Lisanti MP
J Biol Chem. 1996
PubMed ID: 8621645
A "double adaptor" method for improved shotgun library construction.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA
Anal Biochem. 1996
PubMed ID: 8619474
Phosphorylation of caveolin by src tyrosine kinases. The alpha-isoform of caveolin is selectively phosphorylated by v-Src in vivo.
Li S, Seitz R, Lisanti MP
J Biol Chem. 1996
PubMed ID: 8632005
Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle.
Tang Z, Scherer PE, Okamoto T, Song K, Chu C, Kohtz DS, Nishimoto I, Lodish HF, Lisanti MP
J Biol Chem. 1996
PubMed ID: 8567687
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.
Scherer PE, Okamoto T, Chun M, Nishimoto I, Lodish HF, Lisanti MP
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8552590
M-caveolin, a muscle-specific caveolin-related protein.
Way M, Parton RG
FEBS Lett. 1995
PubMed ID: 8521953
Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe.
Scherer PE, Tang Z, Chun M, Sargiacomo M, Lodish HF, Lisanti MP
J Biol Chem. 1995
PubMed ID: 7608210
The primary sequence of murine caveolin reveals a conserved consensus site for phosphorylation by protein kinase C.
Tang ZL, Scherer PE, Lisanti MP
Gene. 1994
PubMed ID: 7926819
In vitro phosphorylation of caveolin-rich membrane domains: identification of an associated serine kinase activity as a casein kinase II-like enzyme.
Sargiacomo M, Scherer PE, Tang ZL, Casanova JE, Lisanti MP
Oncogene. 1994
PubMed ID: 8058322
The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles.
Glenney JR
FEBS Lett. 1992
PubMed ID: 1360410
[An evaluation of the efficacy of dispensary care as a method for the active detection of skin melanoma]
Kurdina MI, Denisov LE
Klin Med (Mosk). 1992
PubMed ID: 1294831
The publication is not currently in our database, click on the link below to see it on pubmed.
PubMed ID:

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	857	12389	25404
EnsEMBL Gene(s)	ENSG00000105974	ENSMUSG00000007655	ENSRNOG00000006694
Unigene	Hs.74034	Mm.28278	Rn.22518
Homologene	CAV1	Cav1	Cav1
OMIM	601047	N/A	N/A
GeneCards	CAV1	N/A	N/A
Beta Cell Genomics	DT.100038859 DT.100882864 DT.100882878 DT.454239 DT.97862297	DT.94352429 DT.97356712	N/A
Reactome	Q03135	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	857	12389	25404

External resources from NIDDK Consortium Interconnectivity Network Top Help

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View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
CAV1	FLOT1	IntAct, BioGRID	empirical	10212252
CAV1	PROCR	IntAct	empirical	20826780
CAV1	NEU3	HPRD, BioGRID	empirical	12011038
CAV1	TMED2	IntAct	empirical	20427317
CAV1	TMED10	IntAct	empirical	20427317
CAV1	PRKCDBP	MINT	empirical	19262564
CAV1	CSK	HPRD, BioGRID	empirical	11805080
CAV1	CSNK2A1	HPRD	empirical	8058322
CAV1	CSNK2A2	HPRD	empirical	8058322
CAV1	ADRBK1	HPRD, BioGRID	empirical	10085129
CAV1	DAG1	BioGRID	empirical	11724572
CAV1	STOML3	HPRD	empirical	12122055
CAV1	CYB5R3	IntAct	empirical	15293782
CAV1	DMBT1	IntAct	empirical	17353931
CAV1	DNM1	HPRD	empirical	11956154
CAV1	S1PR1	HPRD, BioGRID	empirical	10921915
CAV1	EDNRB	HPRD, BioGRID	empirical	12694195
CAV1	EGFR	HPRD, IntAct, BioGRID	empirical	9374534 16799092 15657067 16407214 19446582 12388423
CAV1	ERBB2	HPRD	empirical	9685399
CAV1	ESR1	HPRD, BioGRID	empirical	11563984
CAV1	F2R	IntAct	empirical	20826780
CAV1	FLNA	HPRD	empirical	10637311
CAV1	FLOT2	HPRD, IntAct, BioGRID	empirical	10212252 15293782
CAV1	ABL1	HPRD	empirical	16151024
CAV1	FYN	HPRD	empirical	12529448
CAV1	CLIC4	BioGRID	empirical	11563969
CAV1	GJA1	HPRD	empirical	11980479
CAV1	GJA3	HPRD	empirical	11980479
CAV1	GJB1	BioGRID	empirical	11980479
CAV1	GJB2	HPRD, BioGRID	empirical	11980479
CAV1	GNAI2	HPRD	empirical	8621645
CAV1	PTRF	IntAct	empirical	18191225
CAV1	GRK5	HPRD, BioGRID	empirical	10085129
CAV1	GRB7	HPRD	empirical	11075810
CAV1	STRN4	HPRD	empirical	11707266
CAV1	HRAS	HPRD, MINT	empirical	8621645
CAV1	HSPA5	IntAct	empirical	19632185
CAV1	HTR1F	HPRD	empirical	15190056
CAV1	ID1	IntAct	empirical	17855368
CAV1	IGF1R	HPRD	empirical	18632619
CAV1	IGFBP3	HPRD	empirical	14576164
CAV1	IGHA1	IntAct	empirical	17353931
CAV1	APP	HPRD, BioGRID	empirical	9553108
CAV1	IGKC	IntAct	empirical	17353931
CAV1	FAS	IntAct	empirical	21382479
CAV1	AQP3	BioGRID	empirical	14675200
CAV1	ILK	HPRD	empirical	15722199
CAV1	INSR	HPRD, BioGRID	empirical	10598578
CAV1	IRS1	HPRD	empirical	15003536
CAV1	AR	HPRD	empirical	11278309
CAV1	KDR	HPRD	empirical	12529448
CAV1	RHOA	HPRD, MIPS, BioGRID	empirical	9647788 20460433
CAV1	RHOC	BioGRID	empirical	20460433
CAV1	LRP1	HPRD	empirical	14593097
CAV1	SMAD2	BioGRID	empirical	11102446
CAV1	MMP14	HPRD	empirical	15466865
CAV1	NEDD8	IntAct	empirical	17353931
CAV1	NGFR	HPRD, BioGRID	empirical	9867838
CAV1	NOS2	HPRD, BioGRID	empirical	11114180
CAV1	NOS3	HPRD, BioGRID	empirical	8910295
CAV1	CNOT3	Sanger Interaction Map	predicted	15345047
CAV1	NTRK1	HPRD, BioGRID	empirical	9867838
CAV1	PDGFRA	HPRD, BioGRID	empirical	10066366
CAV1	PDGFRB	BioGRID	empirical	10066366
CAV1	ABCB1	HPRD, MINT	empirical	15498565
CAV1	PLD1	HPRD	empirical	12429840 10090765
CAV1	PLD2	HPRD, BioGRID	empirical	10675563 14675200
CAV1	POU3F3	IntAct	empirical	17353931
CAV1	PRKACA	BioGRID	empirical	11546661
CAV1	RADIL	IntAct	empirical	17353931
CAV1	MAPK1	HPRD, BioGRID	empirical	12388423
CAV1	MAPK3	HPRD, BioGRID	empirical	12388423
CAV1	PRNP	HPRD	empirical	10988071
CAV1	PTEN	HPRD, MINT	empirical	12176037
CAV1	PTGS2	HPRD	empirical	11432874
CAV1	PTPN1	HPRD, MINT, BioGRID	empirical	12176037 16388599
CAV1	PTPN6	HPRD, MINT, BioGRID	empirical	12176037
CAV1	PTPN11	HPRD, MINT, BioGRID	empirical	12176037
CAV1	PTPRF	HPRD, MINT, BioGRID	empirical	12176037
CAV1	RAC1	HPRD, MINT, BioGRID	empirical	15976327 17658519 20460433
CAV1	RCVRN	HPRD, BioGRID	empirical	12507501
CAV1	ACTB	IntAct	empirical	15293782
CAV1	GRK1	HPRD, BioGRID	empirical	10085129
CAV1	SCP2	HPRD, IntAct, BioGRID	empirical	15182174
CAV1	BID	IntAct	empirical	21382479
CAV1	FAM113A	IntAct	empirical	17353931
CAV1	BMX	HPRD, BioGRID	empirical	11751885
CAV1	SOS1	HPRD	empirical	15976327
CAV1	SRC	HPRD, MINT, BioGRID	empirical	8910575 8632005 8621645
CAV1	STRN	HPRD, MINT	empirical	11707266 1177266
CAV1	BSG	HPRD, Reactome	empirical	15201341 14707126
CAV1	BST1	HPRD	empirical	11866528
CAV1	BTK	HPRD, BioGRID	empirical	11751885
CAV1	TGFBR1	HPRD	empirical	11102446
CAV1	TNF	BioGRID	empirical	12753742
CAV1	TNFRSF1A	BioGRID	empirical	12753742
CAV1	TNFRSF1B	HPRD, BioGRID	empirical	11112773
CAV1	TRAF2	HPRD, MINT	empirical	11112773 11805080
CAV1	TRAF6	HPRD	empirical	14665433
CAV1	TRPC1	HPRD, BioGRID	empirical	12732636 10980191
CAV1	TSC2	BioGRID	empirical	12147258
CAV1	UBC	BioGRID	empirical	21041450 21139048 21890473 21906983
CAV1	MALL	HPRD	empirical	1294831
CAV1	AKAP1	HPRD	empirical	11546661
CAV1	SDPR	MINT	empirical	19262564
CAV1	NKD2	BioGRID	empirical	20177058
CAV1	CAV1	HPRD, IntAct	empirical	11114180 15293782
CAV1	CAV2	HPRD, IntAct, BioGRID	empirical	12414992 9361015 15293782 10212252
CAV1	TRADD	BioGRID	empirical	11112773
CAV1	WASL	Reactome	predicted	16807357 16722822 16234328
CAV1	UBE2M	IntAct	empirical	17353931
CAV1	CD40	HPRD	empirical	14665433
CAV1	CD59	IntAct	empirical	20427317