Home TSLP
|
Regions Overlapping this Feature:
Rat: 1
Other Regions: 1 Available
Other Regions: 1 Available
| Locus | Species | Chromosomal Location | Mb | Number of genes |
|---|---|---|---|---|
| Iddm35 | Rat | chr18:4320091..76880933 | 72.56 | 466 |
(Human) GRCh37 - chr5:110405760..110413722 (7.96 kb) View in Genome Browser
(Mouse) NCBIM37 - chr18:32975037..32979453 (4.42 kb) View in Genome Browser
(Rat) RGSC3.4 - chr18:25268082..25274558 (6.48 kb) View in Genome Browser
HaemAtlas Expression Table for TSLP:|
Expression Legend
|
|
|
Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
| no data | no data | no data | no data | no data | no data | |||||||
Expression Legend
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Expression Legend
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for TSLP:The TSLP interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| TSLP | IL7R | HPRD | empirical | 11418668 |
| TSLP | PRNP | IntAct | empirical | 18482256 |
| TSLP | CRLF2 | HPRD | empirical | 11418668 |
| TSLP | STAT3 | HPRD | empirical | 11418668 10570284 |
| TSLP | STAT5A | HPRD | empirical | 11418668 10570284 |
| TSLP | IKBKG | BioGRID | empirical | 20098747 |
|
|
||||||||||||
|
||||||||||||
|
||||||||||||
|
||||||||||||
|
||||||||||||
|
|
|
|||||||||
|
|
|
|||||||||
|
|
|
|||||||||
|
|
|
|||||||||
|
|
|
Publications: 168
-
Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways.
Li DQ, Zhang L, Pflugfelder SC, De Paiva CS, Zhang X, Zhao G, Zheng X, Su Z, Qu Y
J Allergy Clin Immunol. 2011
PubMed ID: 21820713
-
The human cytokine TSLP triggers a cell-autonomous dendritic cell migration in confined environments.
Fernandez MI, Heuzé ML, Martinez-Cingolani C, Volpe E, Donnadieu MH, Piel M, Homey B, Lennon-Duménil AM, Soumelis V
Blood. 2011
PubMed ID: 21772055
-
IgE induces transcriptional regulation of thymic stromal lymphopoietin in human airway smooth muscle cells.
Redhu NS, Saleh A, Lee HC, Halayko AJ, Ziegler SF, Gounni AS
J Allergy Clin Immunol. 2011
PubMed ID: 21835441
-
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.
Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF, Comeau MR, Artis D
Nature. 2011
PubMed ID: 21841801
-
CD34+ -derived Langerhans cell-like cells are different from epidermal Langerhans cells in their response to thymic stromal lymphopoietin.
Nguyen VA, Dubrac S, Forstner M, Huter O, Del Frari B, Romani N, Ebner S
J Cell Mol Med. 2011
PubMed ID: 21054781
-
Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation.
Reardon C, Lechmann M, Brüstle A, Gareau MG, Shuman N, Philpott D, Ziegler SF, Mak TW
Immunity. 2011
PubMed ID: 21820333
-
Thymic stromal lymphopoietin is produced by dendritic cells.
Kashyap M, Rochman Y, Spolski R, Samsel L, Leonard WJ
J Immunol. 2011
PubMed ID: 21690322
-
Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood.
Hong X, Wang G, Liu X, Kumar R, Tsai HJ, Arguelles L, Hao K, Pearson C, Ortiz K, Bonzagni A, Apollon S, Fu L, Caruso D, Pongracic JA, Schleimer R, Holt PG, Bauchner H, Wang X
J Allergy Clin Immunol. 2011
PubMed ID: 21689850
-
The genetics of asthma and allergic disease: a 21st century perspective.
Ober C, Yao TC
Immunol Rev. 2011
PubMed ID: 21682736
-
TSLP enhances the function of helper type 2 cells.
Kitajima M, Lee HC, Nakayama T, Ziegler SF
Eur J Immunol. 2011
PubMed ID: 21484783
-
IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin.
Oh MH, Oh SY, Yu J, Myers AC, Leonard WJ, Liu YJ, Zhu Z, Zheng T
J Immunol. 2011
PubMed ID: 21576506
-
Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells.
Moon PD, Kim HM
Cytokine. 2011
PubMed ID: 21463955
-
Thymic stromal lymphopoietin is a key mediator of breast cancer progression.
Olkhanud PB, Rochman Y, Bodogai M, Malchinkhuu E, Wejksza K, Xu M, Gress RE, Hesdorffer C, Leonard WJ, Biragyn A
J Immunol. 2011
PubMed ID: 21490155
-
Secretion of thymic stromal lymphopoietin from human keratinocytes in response to Malassezia yeasts.
Ishibashi Y, Sugawara K, Sugita T, Nishikawa A
J Dermatol Sci. 2011
PubMed ID: 21458958
-
Viral infection induces Thymic stromal lymphopoietin (TSLP) in human keratinocytes.
Kawasaki J, Ushio H, Kinoshita H, Fukai T, Niyonsaba F, Takai T, Ogawa H, Okumura K, Ikeda S
J Dermatol Sci. 2011
PubMed ID: 21440421
-
Novel cytokines and cytokine-producing T cells in allergic disorders.
Wisniewski JA, Borish L
Allergy Asthma Proc. 2011
PubMed ID: 21439160
-
Essential role of NF-κB and AP-1 transcription factors in TNF-α-induced TSLP expression in human airway smooth muscle cells.
Redhu NS, Saleh A, Halayko AJ, Ali AS, Gounni AS
Am J Physiol Lung Cell Mol Physiol. 2011
PubMed ID: 21148792
-
Thymic stromal lymphopoietin interferes with airway tolerance by suppressing the generation of antigen-specific regulatory T cells.
Lei L, Zhang Y, Yao W, Kaplan MH, Zhou B
J Immunol. 2011
PubMed ID: 21242516
-
Filaggrin knockdown and Toll-like receptor 3 (TLR3) stimulation enhanced the production of thymic stromal lymphopoietin (TSLP) from epidermal layers.
Lee KH, Cho KA, Kim JY, Kim JY, Baek JH, Woo SY, Kim JW
Exp Dermatol. 2011
PubMed ID: 21255094
-
TSLP from RSV-stimulated rat airway epithelial cells activates myeloid dendritic cells.
Qiao J, Li A, Jin X
Immunol Cell Biol. 2011
PubMed ID: 20603637
-
Genetic variants of TSLP and asthma in an admixed urban population.
Liu M, Rogers L, Cheng Q, Shao Y, Fernandez-Beros ME, Hirschhorn JN, Lyon HN, Gajdos ZK, Vedantam S, Gregersen P, Seldin MF, Bleck B, Ramasamy A, Hartikainen AL, Jarvelin MR, Kuokkanen M, Laitinen T, Eriksson J, Lehtimäki T, Raitakari OT, Reibman J
PLoS One. 2011
PubMed ID: 21966427
-
Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes.
Masuko H, Sakamoto T, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N
Int J Chron Obstruct Pulmon Dis. 2011
PubMed ID: 21468164
-
Flagellin induces the expression of thymic stromal lymphopoietin in human keratinocytes via toll-like receptor 5.
Le TA, Takai T, Vu AT, Kinoshita H, Chen X, Ikeda S, Ogawa H, Okumura K
Int Arch Allergy Immunol. 2011
PubMed ID: 21109746
-
Role of thymic stromal lymphopoietin in the pathogenesis of nasal polyposis.
Liu T, Li TL, Zhao F, Xie C, Liu AM, Chen X, Song C, Cheng L, Yang PC
Am J Med Sci. 2011
PubMed ID: 20924287
-
The role of thymic stromal lymphopoietin (TSLP) in allergic disorders.
Ziegler SF
Curr Opin Immunol. 2010
PubMed ID: 21109412
-
Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model.
Briot A, Lacroix M, Robin A, Steinhoff M, Deraison C, Hovnanian A
J Invest Dermatol. 2010
PubMed ID: 20703245
-
TSLP polymorphisms are associated with asthma in a sex-specific fashion.
Hunninghake GM, Soto-Quirós ME, Avila L, Kim HP, Lasky-Su J, Rafaels N, Ruczinski I, Beaty TH, Mathias RA, Barnes KC, Wilk JB, O'Connor GT, Gauderman WJ, Vora H, Baurley JW, Gilliland F, Liang C, Sylvia JS, Klanderman BJ, Sharma SS, Himes BE, Bossley CJ, Israel E, Raby BA, Bush A, Choi AM, Weiss ST, Celedón JC
Allergy. 2010
PubMed ID: 20560908
-
Comprehensive Association Analysis of Candidate Genes for Generalized Vitiligo Supports XBP1, FOXP3, and TSLP.
Birlea SA, Jin Y, Bennett DC, Herbstman DM, Wallace MR, McCormack WT, Kemp EH, Gawkrodger DJ, Weetman AP, Picardo M, Leone G, Taïeb A, Jouary T, Ezzedine K, van Geel N, Lambert J, Overbeck A, Fain PR, Spritz RA
J Invest Dermatol. 2010
PubMed ID: 21085187
-
Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling.
Rochman Y, Kashyap M, Robinson GW, Sakamoto K, Gomez-Rodriguez J, Wagner KU, Leonard WJ
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20974963
-
Increased affected skin gene expression and serum levels of thymic stromal lymphopoietin in atopic dermatitis.
Alysandratos KD, Angelidou A, Vasiadi M, Zhang B, Kalogeromitros D, Katsarou-Katsari A, Theoharides TC
Ann Allergy Asthma Immunol. 2010
PubMed ID: 21055671
-
Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice.
Tsai M, Chen CC, Mukai K, Song CH, Thompson LJ, Ziegler SF, Tam SY, Galli SJ
Am J Pathol. 2010
PubMed ID: 20829437
-
Development and characterization of monoclonal antibodies against mouse TSLP.
Li X, Han X, Wang S, Duan Z
Hybridoma (Larchmt). 2010
PubMed ID: 21050044
-
Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance.
Blázquez AB, Mayer L, Berin MC
Gastroenterology. 2010
PubMed ID: 20600023
-
Injury to the stratum corneum induces in vivo expression of human thymic stromal lymphopoietin in the epidermis.
Angelova-Fischer I, Fernandez IM, Donnadieu MH, Bulfone-Paus S, Zillikens D, Fischer TW, Soumelis V
J Invest Dermatol. 2010
PubMed ID: 20555350
-
Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans.
Guo PF, Du MR, Wu HX, Lin Y, Jin LP, Li DJ
Blood. 2010
PubMed ID: 20538796
-
Basophils induce Th2 immunity: is this final answer?
Min B
Virulence. 2010
PubMed ID: 21178477
-
Analyses of shared genetic factors between asthma and obesity in children.
Melén E, Himes BE, Brehm JM, Boutaoui N, Klanderman BJ, Sylvia JS, Lasky-Su J
J Allergy Clin Immunol. 2010
PubMed ID: 20816195
-
Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle.
Smelter DF, Sathish V, Thompson MA, Pabelick CM, Vassallo R, Prakash YS
J Immunol. 2010
PubMed ID: 20660708
-
Thymic stromal lymphopoietin-activated invariant natural killer T cells trigger an innate allergic immune response in atopic dermatitis.
Wu WH, Park CO, Oh SH, Kim HJ, Kwon YS, Bae BG, Noh JY, Lee KH
J Allergy Clin Immunol. 2010
PubMed ID: 20624642
-
TSLP Promoter Polymorphisms are Associated with Susceptibility to Bronchial Asthma.
Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, Tamari M
Am J Respir Cell Mol Biol. 2010
PubMed ID: 20656951
-
Polymorphisms in innate immunity genes and risk of childhood leukemia.
Han S, Lan Q, Park AK, Lee KM, Park SK, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Ahn YO, Chanock SJ, Kim H, Rothman N, Kang D
Hum Immunol. 2010
PubMed ID: 20438785
-
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum.
Gao PS, Rafaels NM, Mu D, Hand T, Murray T, Boguniewicz M, Hata T, Schneider L, Hanifin JM, Gallo RL, Gao L, Beaty TH, Beck LA, Leung DY, Barnes KC
J Allergy Clin Immunol. 2010
PubMed ID: 20466416
-
[Dimethylsulfoxide-induced expression of thymic stromal lymphopoietin in human bronchial epithelial cells].
Zhang D, Cai SX, Zhao HJ, Liu LY
Nan Fang Yi Ke Da Xue Xue Bao. 2010
PubMed ID: 20501368
-
Risk of meningioma and common variation in genes related to innate immunity.
Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD
Cancer Epidemiol Biomarkers Prev. 2010
PubMed ID: 20406964
-
Functional regulation of thymic stromal lymphopoietin on proliferation and invasion of trophoblasts in human first-trimester pregnancy.
Wu HX, Guo PF, Jin LP, Liang SS, Li DJ
Hum Reprod. 2010
PubMed ID: 20228393
-
Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells.
Xu G, Zhang L, Wang DY, Xu R, Liu Z, Han DM, Wang XD, Zuo KJ, Li HB
Allergy. 2010
PubMed ID: 19968632
-
Sensing the outside world: TSLP regulates barrier immunity.
Ziegler SF, Artis D
Nat Immunol. 2010
PubMed ID: 20300138
-
Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway.
Semlali A, Jacques E, Koussih L, Gounni AS, Chakir J
J Allergy Clin Immunol. 2010
PubMed ID: 20236697
-
Common variants at 5q22 associate with pediatric eosinophilic esophagitis.
Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H
Nat Genet. 2010
PubMed ID: 20208534
-
The role of thymic stromal lymphopoietin in allergic inflammation and chronic obstructive pulmonary disease.
Fang C, Siew LQ, Corrigan CJ, Ying S
Arch Immunol Ther Exp (Warsz). 2010
PubMed ID: 20143171
-
Thymic stromal lymphopoietin induces early human B-cell proliferation and differentiation.
Scheeren FA, van Lent AU, Nagasawa M, Weijer K, Spits H, Legrand N, Blom B
Eur J Immunol. 2010
PubMed ID: 20127673
-
Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus.
Hanabuchi S, Ito T, Park WR, Watanabe N, Shaw JL, Roman E, Arima K, Wang YH, Voo KS, Cao W, Liu YJ
J Immunol. 2010
PubMed ID: 20173030
-
Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.
Larson RP, Zimmerli SC, Comeau MR, Itano A, Omori M, Iseki M, Hauser C, Ziegler SF
J Immunol. 2010
PubMed ID: 20173025
-
Increased serum thymic stromal lymphopoietin in children with atopic dermatitis.
Lee EB, Kim KW, Hong JY, Jee HM, Sohn MH, Kim KE
Pediatr Allergy Immunol. 2010
PubMed ID: 20444170
-
Thymic stromal lymphopoietin is present in human breast milk.
Macfarlane TV, Seager AL, Moller M, Morgan G, Thornton CA
Pediatr Allergy Immunol. 2010
PubMed ID: 20444169
-
[Effects of different factors on the expression of thymic stromal lymphopoietin in respiratory syncytial virus-infected human airway epithelial cells].
Xia H, Luo LM, Yu HP, Cai SX
Nan Fang Yi Ke Da Xue Xue Bao. 2010
PubMed ID: 20335125
-
Thymic stromal lymphopoietin promotes lung inflammation through activation of dendritic cells.
Li YL, Li HJ, Ji F, Zhang X, Wang R, Hao JQ, Bi WX, Dong L
J Asthma. 2010
PubMed ID: 20170316
-
Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells.
Kamekura R, Kojima T, Takashima A, Koizumi J, Ogasawara N, Go M, Takano K, Murata M, Tanaka S, Ichimiya S, Himi T, Sawada N
Histochem Cell Biol. 2010
PubMed ID: 20077120
-
The influence of TSLP on the allergic response.
Comeau MR, Ziegler SF
Mucosal Immunol. 2010
PubMed ID: 20016474
-
Thymic stromal lymphopoietin.
He R, Geha RS
Ann N Y Acad Sci. 2010
PubMed ID: 20146705
-
Synergistic induction of thymic stromal lymphopoietin by tumor necrosis factor alpha and Th2 cytokine in nasal polyp fibroblasts.
Nonaka M, Fukumoto A, Ogihara N, Sakanushi A, Pawankar R, Yagi T
Am J Rhinol Allergy. 2010
PubMed ID: 20109311
-
Expanding the substantial interactome of NEMO using protein microarrays.
Fenner BJ, Scannell M, Prehn JH
PLoS One. 2010
PubMed ID: 20098747
-
Distinct signal codes generate dendritic cell functional plasticity.
Arima K, Watanabe N, Hanabuchi S, Chang M, Sun SC, Liu YJ
Sci Signal. 2010
PubMed ID: 20086239
-
Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses.
Kido M, Tanaka J, Aoki N, Iwamoto S, Nishiura H, Chiba T, Watanabe N
Infect Immun. 2010
PubMed ID: 19841072
-
Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis.
Matsuda A, Ebihara N, Yokoi N, Kawasaki S, Tanioka H, Inatomi T, de Waal Malefyt R, Hamuro J, Kinoshita S, Murakami A
Invest Ophthalmol Vis Sci. 2010
PubMed ID: 19741251
-
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network.
Chorro L, Sarde A, Li M, Woollard KJ, Chambon P, Malissen B, Kissenpfennig A, Barbaroux JB, Groves R, Geissmann F
J Exp Med. 2009
PubMed ID: 19995948
-
The regulatory role of thymic stromal lymphopoietin (TSLP) in maternal-fetal immune tolerance during early human pregnancy.
Li DJ, Guo PF
J Reprod Immunol. 2009
PubMed ID: 19857905
-
Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells.
Kamekura R, Kojima T, Koizumi J, Ogasawara N, Kurose M, Go M, Harimaya A, Murata M, Tanaka S, Chiba H, Himi T, Sawada N
Cell Tissue Res. 2009
PubMed ID: 19763625
-
Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation.
Miyata M, Nakamura Y, Shimokawa N, Ohnuma Y, Katoh R, Matsuoka S, Okumura K, Ogawa H, Masuyama K, Nakao A
Eur J Immunol. 2009
PubMed ID: 19658093
-
Thymic stromal lymphopoietin expression is increased in nasal epithelial cells of patients with mugwort pollen sensitive-seasonal allergic rhinitis.
Zhu DD, Zhu XW, Jiang XD, Dong Z
Chin Med J (Engl). 2009
PubMed ID: 20079130
-
TSLP and IL-7 use two different mechanisms to regulate human CD4+ T cell homeostasis.
Lu N, Wang YH, Wang YH, Arima K, Hanabuchi S, Liu YJ
J Exp Med. 2009
PubMed ID: 19770269
-
[Expression of thymic stromal lymphopoietin in nasal mucosa of a mouse model with allergic rhinitis].
Xu M, Guo Y
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009
PubMed ID: 20030046
-
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function.
Massacand JC, Stettler RC, Meier R, Humphreys NE, Grencis RK, Marsland BJ, Harris NL
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19666528
-
A thymic stromal lymphopoietin gene variant is associated with asthma and airway hyperresponsiveness.
He JQ, Hallstrand TS, Knight D, Chan-Yeung M, Sandford A, Tripp B, Zamar D, Bossé Y, Kozyrskyj AL, James A, Laprise C, Daley D
J Allergy Clin Immunol. 2009
PubMed ID: 19539984
-
Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation.
Knisz J, Banks A, McKeag L, Metcalfe DD, Rothman PB, Brown JM
Clin Immunol. 2009
PubMed ID: 19427817
-
FcepsilonRI-mediated thymic stromal lymphopoietin production by interleukin-4-primed human mast cells.
Okayama Y, Okumura S, Sagara H, Yuki K, Sasaki T, Watanabe N, Fueki M, Sugiyama K, Takeda K, Fukuda T, Saito H, Ra C
Eur Respir J. 2009
PubMed ID: 19164348
-
Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2.
Kouzaki H, O'Grady SM, Lawrence CB, Kita H
J Immunol. 2009
PubMed ID: 19561109
-
Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects.
Corrigan CJ, Jayaratnam A, Wang Y, Liu Y, de Waal Malefyt R, Meng Q, Kay AB, Phipps S, Lee TH, Ying S
Allergy. 2009
PubMed ID: 19187393
-
Association of thymic stromal lymphopoietin gene -847C>T polymorphism in generalized vitiligo.
Cheong KA, Chae SC, Kim YS, Kwon HB, Chung HT, Lee AY
Exp Dermatol. 2009
PubMed ID: 19555430
-
Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses.
Wang YH, Liu YJ
Clin Exp Allergy. 2009
PubMed ID: 19400908
-
Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma.
Demehri S, Morimoto M, Holtzman MJ, Kopan R
PLoS Biol. 2009
PubMed ID: 19557146
-
Regulation of helminth-induced Th2 responses by thymic stromal lymphopoietin.
Ramalingam TR, Pesce JT, Mentink-Kane MM, Madala S, Cheever AW, Comeau MR, Ziegler SF, Wynn TA
J Immunol. 2009
PubMed ID: 19414799
-
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
Briot A, Deraison C, Lacroix M, Bonnart C, Robin A, Besson C, Dubus P, Hovnanian A
J Exp Med. 2009
PubMed ID: 19414552
-
Common variation in genes related to innate immunity and risk of adult glioma.
Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ
Cancer Epidemiol Biomarkers Prev. 2009
PubMed ID: 19423540
-
[Respiratory syncytial virus infection promotes the production of thymic stromal lymphopoietin and accelerates Th2 inflammation in mouse airway]
Xia H, Cai SX, Tong WC, Luo LM, Yu HP
Nan Fang Yi Ke Da Xue Xue Bao. 2009
PubMed ID: 19403406
-
Thymic stromal lymphopoietin as a mediator of crosstalk between bronchial smooth muscles and mast cells.
Allakhverdi Z, Comeau MR, Jessup HK, Delespesse G
J Allergy Clin Immunol. 2009
PubMed ID: 19348931
-
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.
Taylor BC, Zaph C, Troy AE, Du Y, Guild KJ, Comeau MR, Artis D
J Exp Med. 2009
PubMed ID: 19273626
-
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.
Gudbjartsson DF, Bjornsdottir US, Halapi E, Helgadottir A, Sulem P, Jonsdottir GM, Thorleifsson G, Helgadottir H, Steinthorsdottir V, Stefansson H, Williams C, Hui J, Beilby J, Warrington NM, James A, Palmer LJ, Koppelman GH, Heinzmann A, Krueger M, Boezen HM, Wheatley A, Altmuller J, Shin HD, Uh ST, Cheong HS, Jonsdottir B, Gislason D, Park CS, Rasmussen LM, Porsbjerg C, Hansen JW, Backer V, Werge T, Janson C, Jönsson UB, Ng MC, Chan J, So WY, Ma R, Shah SH, Granger CB, Quyyumi AA, Levey AI, Vaccarino V, Reilly MP, Rader DJ, Williams MJ, van Rij AM, Jones GT, Trabetti E, Malerba G, Pignatti PF, Boner A, Pescollderungg L, Girelli D, Olivieri O, Martinelli N, Ludviksson BR, Ludviksdottir D, Eyjolfsson GI, Arnar D, Thorgeirsson G, Deichmann K, Thompson PJ, Wjst M, Hall IP, Postma DS, Gislason T, Gulcher J, Kong A, Jonsdottir I, Thorsteinsdottir U, Stefansson K
Nat Genet. 2009
PubMed ID: 19198610
-
Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Harada M, Hirota T, Jodo AI, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Yoshihara S, Ebisawa M, Saito H, Matsumoto K, Nakamura Y, Ziegler SF, Tamari M
Am J Respir Cell Mol Biol. 2009
PubMed ID: 18787178
-
CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells.
Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ
Am J Respir Cell Mol Biol. 2009
PubMed ID: 18757306
-
Overexpression of thymic stromal lymphopoietin in allergic rhinitis.
Mou Z, Xia J, Tan Y, Wang X, Zhang Y, Zhou B, Li H, Han D
Acta Otolaryngol. 2009
PubMed ID: 18720075
-
Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.
Zhang Z, Hener P, Frossard N, Kato S, Metzger D, Li M, Chambon P
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19188585
-
TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses.
Headley MB, Zhou B, Shih WX, Aye T, Comeau MR, Ziegler SF
J Immunol. 2009
PubMed ID: 19155513
-
Induction of thymic stromal lymphopoietin expression in keratinocytes is necessary for generating an atopic dermatitis upon application of the active vitamin D3 analogue MC903 on mouse skin.
Li M, Hener P, Zhang Z, Ganti KP, Metzger D, Chambon P
J Invest Dermatol. 2009
PubMed ID: 18650845
-
Protein microarray analysis identifies human cellular prion protein interactors.
Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H
Neuropathol Appl Neurobiol. 2009
PubMed ID: 18482256
-
TSLP in epithelial cell and dendritic cell cross talk.
Liu YJ
Adv Immunol. 2009
PubMed ID: 19231591
-
Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
J Allergy Clin Immunol. 2009
PubMed ID: 19056108
-
Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions.
Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T
Clin Exp Allergy. 2009
PubMed ID: 19055649
-
The role of thymic stromal lymphopoietin in CD8+ T cell homeostasis.
Rochman Y, Leonard WJ
J Immunol. 2008
PubMed ID: 19017958
-
Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation.
Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Nakao A
J Allergy Clin Immunol. 2008
PubMed ID: 18926564
-
Reversal of thymic stromal lymphopoietin-induced airway inflammation through inhibition of Th2 responses.
Zhou B, Headley MB, Aye T, Tocker J, Comeau MR, Ziegler SF
J Immunol. 2008
PubMed ID: 18941246
-
Imidazoquinoline acts as immune adjuvant for functional alteration of thymic stromal lymphopoietin-mediated allergic T cell response.
Torii Y, Ito T, Amakawa R, Sugimoto H, Amuro H, Tanijiri T, Katashiba Y, Ogata M, Yokoi T, Fukuhara S
J Immunol. 2008
PubMed ID: 18832690
-
Cutting edge: Inhibition of NF-kappaB-mediated TSLP expression by retinoid X receptor.
Lee HC, Headley MB, Iseki M, Ikuta K, Ziegler SF
J Immunol. 2008
PubMed ID: 18832669
-
Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.
Mazzucchelli R, Hixon JA, Spolski R, Chen X, Li WQ, Hall VL, Willette-Brown J, Hurwitz AA, Leonard WJ, Durum SK
Blood. 2008
PubMed ID: 18664628
-
Intradermal administration of thymic stromal lymphopoietin induces a T cell- and eosinophil-dependent systemic Th2 inflammatory response.
Jessup HK, Brewer AW, Omori M, Rickel EA, Budelsky AL, Yoon BR, Ziegler SF, Comeau MR
J Immunol. 2008
PubMed ID: 18768889
-
FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B lymphopoiesis.
Jensen CT, Kharazi S, Böiers C, Cheng M, Lübking A, Sitnicka E, Jacobsen SE
Blood. 2008
PubMed ID: 18566323
-
IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development.
Vang KB, Yang J, Mahmud SA, Burchill MA, Vegoe AL, Farrar MA
J Immunol. 2008
PubMed ID: 18714000
-
TSLP acts on infiltrating effector T cells to drive allergic skin inflammation.
He R, Oyoshi MK, Garibyan L, Kumar L, Ziegler SF, Geha RS
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18711124
-
Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease.
Ying S, O'Connor B, Ratoff J, Meng Q, Fang C, Cousins D, Zhang G, Gu S, Gao Z, Shamji B, Edwards MJ, Lee TH, Corrigan CJ
J Immunol. 2008
PubMed ID: 18684970
-
Therapy directed against thymic stromal lymphopoietin.
Edwards MJ
Drug News Perspect. 2008
PubMed ID: 18836588
-
Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis.
Miyata M, Hatsushika K, Ando T, Shimokawa N, Ohnuma Y, Katoh R, Suto H, Ogawa H, Masuyama K, Nakao A
Eur J Immunol. 2008
PubMed ID: 18461563
-
Thymic stromal lymphopoietin: a new cytokine in asthma.
Rochman Y, Leonard WJ
Curr Opin Pharmacol. 2008
PubMed ID: 18450510
-
Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.
Demehri S, Liu Z, Lee J, Lin MH, Crosby SD, Roberts CJ, Grigsby PW, Miner JH, Farr AG, Kopan R
PLoS Biol. 2008
PubMed ID: 18507503
-
Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans.
Hunninghake GM, Lasky-Su J, Soto-Quirós ME, Avila L, Liang C, Lake SL, Hudson TJ, Spesny M, Fournier E, Sylvia JS, Freimer NB, Klanderman BJ, Raby BA, Celedón JC
Am J Respir Crit Care Med. 2008
PubMed ID: 18244952
-
Human TSLP-educated DCs.
Wang J, Xing F
Cell Mol Immunol. 2008
PubMed ID: 18445339
-
Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin.
Bleck B, Tse DB, Curotto de Lafaille MA, Zhang F, Reibman J
J Clin Immunol. 2008
PubMed ID: 18049884
-
Lung dendritic cells: targets for therapy in allergic disease.
Lambrecht BN, Hammad H
Chem Immunol Allergy. 2008
PubMed ID: 18802348
-
Control and regulation of peripheral tolerance in allergic inflammatory disease: therapeutic consequences.
Li L, Boussiotis VA
Chem Immunol Allergy. 2008
PubMed ID: 18802347
-
Regulatory role of T lymphocytes in atopic dermatitis.
Werfel T, Wittmann M
Chem Immunol Allergy. 2008
PubMed ID: 18802341
-
TSLP-induced placental DC activation and IL-10(+) NK cell expansion: comparative study based on BALB/c x C57BL/6 and NOD/SCID x C57BL/6 pregnant models.
Lin Y, Zhong Y, Shen W, Chen Y, Shi J, Di J, Zeng S, Saito S
Clin Immunol. 2008
PubMed ID: 17974483
-
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F
J Clin Invest. 2007
PubMed ID: 18060034
-
Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice.
Chappaz S, Flueck L, Farr AG, Rolink AG, Finke D
Blood. 2007
PubMed ID: 17702899
-
[Signal transduction in respiratory syncytial virus infection-induced thymic stromal lymphopoietin expression in human epithelial cells]
Tu HY, Chen X, Li J
Nan Fang Yi Ke Da Xue Xue Bao. 2007
PubMed ID: 17959543
-
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells.
Wang YH, Angkasekwinai P, Lu N, Voo KS, Arima K, Hanabuchi S, Hippe A, Corrigan CJ, Dong C, Homey B, Yao Z, Ying S, Huston DP, Liu YJ
J Exp Med. 2007
PubMed ID: 17635955
-
Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation.
Liu YJ
J Allergy Clin Immunol. 2007
PubMed ID: 17666213
-
Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease.
Zhang K, Shan L, Rahman MS, Unruh H, Halayko AJ, Gounni AS
Am J Physiol Lung Cell Mol Physiol. 2007
PubMed ID: 17513456
-
Cutting edge: direct action of thymic stromal lymphopoietin on activated human CD4+ T cells.
Rochman I, Watanabe N, Arima K, Liu YJ, Leonard WJ
J Immunol. 2007
PubMed ID: 17513717
-
A possible role for TSLP in inflammatory arthritis.
Koyama K, Ozawa T, Hatsushika K, Ando T, Takano S, Wako M, Suenaga F, Ohnuma Y, Ohba T, Katoh R, Sugiyama H, Hamada Y, Ogawa H, Okumura K, Nakao A
Biochem Biophys Res Commun. 2007
PubMed ID: 17416344
-
Thymic stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells.
Ebner S, Nguyen VA, Forstner M, Wang YH, Wolfram D, Liu YJ, Romani N
J Allergy Clin Immunol. 2007
PubMed ID: 17320941
-
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells.
Allakhverdi Z, Comeau MR, Jessup HK, Yoon BR, Brewer A, Chartier S, Paquette N, Ziegler SF, Sarfati M, Delespesse G
J Exp Med. 2007
PubMed ID: 17242164
-
Induction of IL-4 expression in CD4(+) T cells by thymic stromal lymphopoietin.
Omori M, Ziegler S
J Immunol. 2007
PubMed ID: 17237387
-
Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB.
Lee HC, Ziegler SF
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17213320
-
Differential role of thymic stromal lymphopoietin in the induction of airway hyperreactivity and Th2 immune response in antigen-induced asthma with respect to natural killer T cell function.
Nagata Y, Kamijuku H, Taniguchi M, Ziegler S, Seino K
Int Arch Allergy Immunol. 2007
PubMed ID: 17652941
-
TSLP is involved in expansion of early thymocyte progenitors.
Jiang Q, Coffield VM, Kondo M, Su L
BMC Immunol. 2007
PubMed ID: 17640367
-
TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation.
Liu YJ, Soumelis V, Watanabe N, Ito T, Wang YH, Malefyt Rde W, Omori M, Zhou B, Ziegler SF
Annu Rev Immunol. 2007
PubMed ID: 17129180
-
Thymic stromal lymphopoietin:a potential therapeutic target for allergy and asthma.
Huston DP, Liu YJ
Curr Allergy Asthma Rep. 2006
PubMed ID: 16899198
-
Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis.
Li M, Hener P, Zhang Z, Kato S, Metzger D, Chambon P
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16880407
-
Thymic stromal lymphopoietin in normal and pathogenic T cell development and function.
Ziegler SF, Liu YJ
Nat Immunol. 2006
PubMed ID: 16785889
-
Tweaking of memory T helper 2 cells by TSLP.
Kapsenberg M
Immunity. 2006
PubMed ID: 16782024
-
Thymic stromal lymphopoietin: master switch for allergic inflammation.
Liu YJ
J Exp Med. 2006
PubMed ID: 16432252
-
Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP.
Jiang Q, Su H, Knudsen G, Helms W, Su L
BMC Immunol. 2006
PubMed ID: 16579866
-
A role for TSLP in the development of inflammation in an asthma model.
Al-Shami A, Spolski R, Kelly J, Keane-Myers A, Leonard WJ
J Exp Med. 2005
PubMed ID: 16172260
-
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
-
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
-
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity.
Ying S, O'Connor B, Ratoff J, Meng Q, Mallett K, Cousins D, Robinson D, Zhang G, Zhao J, Lee TH, Corrigan C
J Immunol. 2005
PubMed ID: 15944327
-
Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential.
Watanabe N, Hanabuchi S, Marloie-Provost MA, Antonenko S, Liu YJ, Soumelis V
Blood. 2005
PubMed ID: 15741223
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
-
The DNA sequence and comparative analysis of human chromosome 5.
Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM
Nature. 2004
PubMed ID: 15372022
-
Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment.
Vosshenrich CA, Cumano A, Müller W, Di Santo JP, Vieira P
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15263090
-
A role for thymic stromal lymphopoietin in CD4(+) T cell development.
Al-Shami A, Spolski R, Kelly J, Fry T, Schwartzberg PL, Pandey A, Mackall CL, Leonard WJ
J Exp Med. 2004
PubMed ID: 15263024
-
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
-
Human thymic stromal lymphopoietin: a novel epithelial cell-derived cytokine and a potential key player in the induction of allergic inflammation.
Soumelis V, Liu YJ
Springer Semin Immunopathol. 2004
PubMed ID: 14999427
-
Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis.
Osborn MJ, Ryan PL, Kirchhof N, Panoskaltsis-Mortari A, Mortari F, Tudor KS
Blood. 2004
PubMed ID: 14512322
-
Human dendritic cells activated by TSLP and CD40L induce proallergic cytotoxic T cells.
Gilliet M, Soumelis V, Watanabe N, Hanabuchi S, Antonenko S, de Waal-Malefyt R, Liu YJ
J Exp Med. 2003
PubMed ID: 12707303
-
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
-
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
-
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.
Soumelis V, Reche PA, Kanzler H, Yuan W, Edward G, Homey B, Gilliet M, Ho S, Antonenko S, Lauerma A, Smith K, Gorman D, Zurawski S, Abrams J, Menon S, McClanahan T, de Waal-Malefyt Rd R, Bazan F, Kastelein RA, Liu YJ
Nat Immunol. 2002
PubMed ID: 12055625
-
Cryoglobulinemic glomerulonephritis in thymic stromal lymphopoietin transgenic mice.
Taneda S, Segerer S, Hudkins KL, Cui Y, Wen M, Segerer M, Wener MH, Khairallah CG, Farr AG, Alpers CE
Am J Pathol. 2001
PubMed ID: 11733384
-
Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation.
Quentmeier H, Drexler HG, Fleckenstein D, Zaborski M, Armstrong A, Sims JE, Lyman SD
Leukemia. 2001
PubMed ID: 11480573
-
Human thymic stromal lymphopoietin preferentially stimulates myeloid cells.
Reche PA, Soumelis V, Gorman DM, Clifford T, Liu Mr, Travis M, Zurawski SM, Johnston J, Liu YJ, Spits H, de Waal Malefyt R, Kastelein RA, Bazan JF
J Immunol. 2001
PubMed ID: 11418668
-
The sequence of the human genome.
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X
Science. 2001
PubMed ID: 11181995
-
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
-
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
-
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
-
Molecular cloning and biological characterization of a novel murine lymphoid growth factor.
Sims JE, Williams DE, Morrissey PJ, Garka K, Foxworthe D, Price V, Friend SL, Farr A, Bedell MA, Jenkins NA, Copeland NG, Grabstein K, Paxton RJ
J Exp Med. 2000
PubMed ID: 10974033
-
Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction.
Isaksen DE, Baumann H, Trobridge PA, Farr AG, Levin SD, Ziegler SF
J Immunol. 1999
PubMed ID: 10570284
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
-
Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro.
Ray RJ, Furlonger C, Williams DE, Paige CJ
Eur J Immunol. 1996
PubMed ID: 8566050
Model Organism Phenotype Links
|
Relevant resources: