CAMK2G

Summary Top Help

Gene Description:

calcium/calmodulin-dependent protein kinase II gamma

Synonyms:

CAMK2G, 5930429P18Rik, CAMKG, CAMK, CAMK-II, Camkg, Camk2g

Orthologs:

Human CAMK2G (protein-coding), Mouse Camk2g (protein-coding), Rat Camk2g (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr10:75572259..75634349 (629 kb) View in Genome Browser

(Mouse) NCBIM37 - chr14:21554097..21613310 (59.21 kb) View in Genome Browser

(Rat) RGSC3.4 - chr15:3729425..3786060 (56.63 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for CAMK2G:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for CAMK2G:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 13

Biocarta: None available

Reactome: 11

NCI-Nature Pathway Interaction Database: 3

Gene Ontology: 21

Publications from PubMed Top Help

Type 1 Diabetes Publications: 5

Publications: 152

PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome.
Mouton-Liger F, Thomas S, Rattenbach R, Magnol L, Larigaldie V, Ledru A, Herault Y, Verney C, Créau N
J Comp Neurol. 2011
PubMed ID: 21491429
CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB.
Oruganti SR, Edin S, Grundström C, Grundström T
Mol Immunol. 2011
PubMed ID: 21513986
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.
Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
J Neurosci. 2011
PubMed ID: 21209221
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis.
Li G, Scull C, Ozcan L, Tabas I
J Cell Biol. 2010
PubMed ID: 21135141
CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells.
Kajihara R, Fukushige S, Shioda N, Tanabe K, Fukunaga K, Inui S
Biochem Biophys Res Commun. 2010
PubMed ID: 20851109
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.
Martinez-Pena y Valenzuela I, Mouslim C, Akaaboune M
J Neurosci. 2010
PubMed ID: 20844140
Intracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes.
Gangopadhyay JP, Ikemoto N
Biochem Biophys Res Commun. 2010
PubMed ID: 20433809
Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function.
Skelding KA, Suzuki T, Gordon S, Xue J, Verrills NM, Dickson PW, Rostas JA
Cell Signal. 2010
PubMed ID: 20060891
Molecular interaction and functional regulation of ClC-3 by Ca2+/calmodulin-dependent protein kinase II (CaMKII) in human malignant glioma.
Cuddapah VA, Sontheimer H
J Biol Chem. 2010
PubMed ID: 20139089
The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo.
Jin XL, O'Neill C
Biol Reprod. 2010
PubMed ID: 19776387
The gamma isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption.
Backs J, Stein P, Backs T, Duncan FE, Grueter CE, McAnally J, Qi X, Schultz RM, Olson EN
Proc Natl Acad Sci U S A. 2010
PubMed ID: 19966304
Non-selective cation channel-mediated Ca2+-entry and activation of Ca2+/calmodulin-dependent kinase II contribute to G2/M cell cycle arrest and survival of irradiated leukemia cells.
Heise N, Palme D, Misovic M, Koka S, Rudner J, Lang F, Salih HR, Huber SM, Henke G
Cell Physiol Biochem. 2010
PubMed ID: 21063097
Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.
Rellos P, Pike AC, Niesen FH, Salah E, Lee WH, von Delft F, Knapp S
PLoS Biol. 2010
PubMed ID: 20668654
Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse.
Chang HY, Minahan K, Merriman JA, Jones KT
Development. 2009
PubMed ID: 19906843
Differential regulation by ATP versus ADP further links CaMKII aggregation to ischemic conditions.
Vest RS, O'Leary H, Bayer KU
FEBS Lett. 2009
PubMed ID: 19840793
Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates tumour necrosis factor-related apoptosis inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells (FLS) by phosphorylation of Akt.
Fujikawa K, Kawakami A, Tanaka F, Iwamoto N, Tamai M, Eguchi K
Clin Exp Rheumatol. 2009
PubMed ID: 20149311
Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure.
Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS
Circ Heart Fail. 2009
PubMed ID: 19919992
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Alpha-kinase anchoring protein alphaKAP interacts with SERCA2A to spatially position Ca2+/calmodulin-dependent protein kinase II and modulate phospholamban phosphorylation.
Singh P, Salih M, Tuana BS
J Biol Chem. 2009
PubMed ID: 19671701
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.
Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I
J Clin Invest. 2009
PubMed ID: 19741297
Ca2+/calmodulin-dependent kinase II signalling cascade mediates P2X7 receptor-dependent inhibition of neuritogenesis in neuroblastoma cells.
Gómez-Villafuertes R, del Puerto A, Díaz-Hernández M, Bustillo D, Díaz-Hernández JI, Huerta PG, Artalejo AR, Garrido JJ, Miras-Portugal MT
FEBS J. 2009
PubMed ID: 19682070
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell. 2009
PubMed ID: 19615732
Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.
Chelu MG, Sarma S, Sood S, Wang S, van Oort RJ, Skapura DG, Li N, Santonastasi M, Müller FU, Schmitz W, Schotten U, Anderson ME, Valderrábano M, Dobrev D, Wehrens XH
J Clin Invest. 2009
PubMed ID: 19603549
Large-scale proteomics analysis of the human kinome.
Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H
Mol Cell Proteomics. 2009
PubMed ID: 19369195
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.
Sehic A, Khuu C, Risnes S, Osmundsen H
Eur J Oral Sci. 2009
PubMed ID: 19320717
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.
Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, Dekosky ST, Lemoine Y, Iwatsubo T, Wavrant-Devrièze F, Dartigues JF, Tzourio C, Buée L, Pasquier F, Berr C, Mann D, Lendon C, Alpérovitch A, Kamboh MI, Amouyel P, Lambert JC
Mol Psychiatry. 2009
PubMed ID: 19204726
DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities.
Lu YM, Shioda N, Han F, Kamata A, Shirasaki Y, Qin ZH, Fukunaga K
Cardiovasc Ther. 2009
PubMed ID: 19207476
Proarrhythmic defects in Timothy syndrome require calmodulin kinase II.
Thiel WH, Chen B, Hund TJ, Koval OM, Purohit A, Song LS, Mohler PJ, Anderson ME
Circulation. 2008
PubMed ID: 19001023
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
[Ca2+/calmodulin-dependent protein kinase signaling: regulatory mechanisms for switching on/off and their involvement in the pathogenesis of various diseases]
Shigeri Y, Ishida A, Sueyoshi N, Kameshita I
Tanpakushitsu Kakusan Koso. 2008
PubMed ID: 18788460
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
Mol Cell. 2008
PubMed ID: 18691976
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Activated Ca2+/calmodulin-dependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation.
Si J, Collins SJ
Cancer Res. 2008
PubMed ID: 18483256
IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells.
Chu CH, Tzang BS, Chen LM, Kuo CH, Cheng YC, Chen LY, Tsai FJ, Tsai CH, Kuo WW, Huang CY
J Endocrinol. 2008
PubMed ID: 18434368
Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.
Correia SS, Bassani S, Brown TC, Lisé MF, Backos DS, El-Husseini A, Passafaro M, Esteban JA
Nat Neurosci. 2008
PubMed ID: 18311135
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.
Bossuyt J, Helmstadter K, Wu X, Clements-Jewery H, Haworth RS, Avkiran M, Martin JL, Pogwizd SM, Bers DM
Circ Res. 2008
PubMed ID: 18218981
Insulin-inhibited and stimulated cultured vascular smooth muscle cell migration are related to divergent effects on protein phosphatase-2A and autonomous calcium/calmodulin-dependent protein kinase II.
Yang M, Kahn AM
Atherosclerosis. 2008
PubMed ID: 17553505
Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.
Morgan AR, Turic D, Jehu L, Hamilton G, Hollingworth P, Moskvina V, Jones L, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J
Am J Med Genet B Neuropsychiatr Genet. 2007
PubMed ID: 17373700
Calcium/calmodulin-dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL).
Ang ES, Zhang P, Steer JH, Tan JW, Yip K, Zheng MH, Joyce DA, Xu J
J Cell Physiol. 2007
PubMed ID: 17477372
Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53.
Duan S, Yao Z, Hou D, Wu Z, Zhu WG, Wu M
EMBO J. 2007
PubMed ID: 17568776
CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells.
Si J, Mueller L, Collins SJ
J Clin Invest. 2007
PubMed ID: 17431504
Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells.
Liu Y, Templeton DM
FEBS Lett. 2007
PubMed ID: 17367784
Maternal microRNAs are essential for mouse zygotic development.
Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA
Genes Dev. 2007
PubMed ID: 17369397
Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.
Wissing J, Jänsch L, Nimtz M, Dieterich G, Hornberger R, Kéri G, Wehland J, Daub H
Mol Cell Proteomics. 2007
PubMed ID: 17192257
Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM
Mol Cell Proteomics. 2007
PubMed ID: 17114649
Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1A/transporter complexes.
Dipace C, Sung U, Binda F, Blakely RD, Galli A
Mol Pharmacol. 2007
PubMed ID: 17032905
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
Nuclear Ca2+/calmodulin-dependent protein kinase II in the murine heart.
Li B, Dedman JR, Kaetzel MA
Biochim Biophys Acta. 2006
PubMed ID: 17069901
Ca2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise.
Rose AJ, Kiens B, Richter EA
J Physiol. 2006
PubMed ID: 16690701
Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL
Mol Cell Proteomics. 2006
PubMed ID: 16452087
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.
Bayer KU, LeBel E, McDonald GL, O'Leary H, Schulman H, De Koninck P
J Neurosci. 2006
PubMed ID: 16436603
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A
Am J Hum Genet. 2006
PubMed ID: 16385451
Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2.
Robison AJ, Bass MA, Jiao Y, MacMillan LB, Carmody LC, Bartlett RK, Colbran RJ
J Biol Chem. 2005
PubMed ID: 16120608
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling.
McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S
J Immunol. 2005
PubMed ID: 16002660
CaMKIIgamma-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation.
Holmfeldt P, Zhang X, Stenmark S, Walczak CE, Gullberg M
EMBO J. 2005
PubMed ID: 15775983
Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia.
Yuan G, Nanduri J, Bhasker CR, Semenza GL, Prabhakar NR
J Biol Chem. 2005
PubMed ID: 15569687
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
Protein kinase Cdelta regulates apoptosis via activation of STAT1.
DeVries TA, Kalkofen RL, Matassa AA, Reyland ME
J Biol Chem. 2004
PubMed ID: 15322115
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Age-associated alteration of gene expression patterns in mouse oocytes.
Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, Sharov AA, Dudekula DB, VanBuren V, Ko MS
Hum Mol Genet. 2004
PubMed ID: 15317747
Evidence of STAT1 phosphorylation modulated by MAPKs, MEK1 and MSK1.
Zhang Y, Cho YY, Petersen BL, Zhu F, Dong Z
Carcinogenesis. 2004
PubMed ID: 14963018
The DNA sequence and comparative analysis of human chromosome 10.
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Nature. 2004
PubMed ID: 15164054
The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.
Chin ER
Proc Nutr Soc. 2004
PubMed ID: 15294044
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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Nature. 2004
PubMed ID: 15057822
Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.
Gaertner TR, Kolodziej SJ, Wang D, Kobayashi R, Koomen JM, Stoops JK, Waxham MN
J Biol Chem. 2004
PubMed ID: 14722083
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Visel A, Thaller C, Eichele G
Nucleic Acids Res. 2004
PubMed ID: 14681479
Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants.
Stange M, Xu L, Balshaw D, Yamaguchi N, Meissner G
J Biol Chem. 2003
PubMed ID: 14532276
The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.
Krapivinsky G, Krapivinsky L, Manasian Y, Ivanov A, Tyzio R, Pellegrino C, Ben-Ari Y, Clapham DE, Medina I
Neuron. 2003
PubMed ID: 14622581
Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.
Cairns BE, Svensson P, Wang K, Hupfeld S, Graven-Nielsen T, Sessle BJ, Berde CB, Arendt-Nielsen L
J Neurophysiol. 2003
PubMed ID: 12815021
Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action.
Trencia A, Perfetti A, Cassese A, Vigliotta G, Miele C, Oriente F, Santopietro S, Giacco F, Condorelli G, Formisano P, Beguinot F
Mol Cell Biol. 2003
PubMed ID: 12808093
Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.
Afroze T, Yang LL, Wang C, Gros R, Kalair W, Hoque AN, Mungrue IN, Zhu Z, Husain M
Am J Physiol Cell Physiol. 2003
PubMed ID: 12660151
Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.
Dimberg A, Karlberg I, Nilsson K, Oberg F
Blood. 2003
PubMed ID: 12637327
Silence analysis of AMPA receptor mutated at the CaM-kinase II phosphorylation site.
Derkach VA
Biophys J. 2003
PubMed ID: 12609872
Phosphorylation of 69-kDa choline acetyltransferase at threonine 456 in response to amyloid-beta peptide 1-42.
Dobransky T, Brewer D, Lajoie G, Rylett RJ
J Biol Chem. 2003
PubMed ID: 12486117
Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo.
Colomer JM, Mao L, Rockman HA, Means AR
Mol Endocrinol. 2003
PubMed ID: 12554746
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
The role of Ca2+/calmodulin-dependent protein kinase II in mechanisms underlying neuronal hyperexcitability induced by repeated, brief exposure to hypoxia or high K+ in rat hippocampal slices.
Yechikhov S, Shchipakina T, Savina T, Kalemenev S, Levin S, Godukhin O
Neurosci Lett. 2002
PubMed ID: 12457733
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Calcium/calmodulin-dependent protein kinase IIdelta 2 and gamma isoforms regulate potassium currents of rat brain capillary endothelial cells under hypoxic conditions.
Balla Z, Hoch B, Karczewski P, Blasig IE
J Biol Chem. 2002
PubMed ID: 11925434
Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.
Nair JS, DaFonseca CJ, Tjernberg A, Sun W, Darnell JE, Chait BT, Zhang JJ
Proc Natl Acad Sci U S A. 2002
PubMed ID: 11972023
Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.
Uddin S, Sassano A, Deb DK, Verma A, Majchrzak B, Rahman A, Malik AB, Fish EN, Platanias LC
J Biol Chem. 2002
PubMed ID: 11839738
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Yamamoto H
Tanpakushitsu Kakusan Koso. 2002
PubMed ID: 11889801
Mutational analysis of sites in sepiapterin reductase phosphorylated by Ca2+/calmodulin-dependent protein kinase II.
Fujimoto K, Takahashi SY, Katoh S
Biochim Biophys Acta. 2002
PubMed ID: 11825621
Cytosolic targeting domains of gamma and delta calmodulin-dependent protein kinase II.
Caran N, Johnson LD, Jenkins KJ, Tombes RM
J Biol Chem. 2001
PubMed ID: 11535587
Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F.
Ahmed ZM, Riazuddin S, Bernstein SL, Ahmed Z, Khan S, Griffith AJ, Morell RJ, Friedman TB, Riazuddin S, Wilcox ER
Am J Hum Genet. 2001
PubMed ID: 11398101
Interaction of phosphorylated tyrosine hydroxylase with 14-3-3 proteins: evidence for a phosphoserine 40-dependent association.
Kleppe R, Toska K, Haavik J
J Neurochem. 2001
PubMed ID: 11359875
Regulation of endothelial cell barrier function by calcium/calmodulin-dependent protein kinase II.
Borbiev T, Verin AD, Shi S, Liu F, Garcia JG
Am J Physiol Lung Cell Mol Physiol. 2001
PubMed ID: 11290523
KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent protein kinase II to phosphorylate phospholipase Cbeta3 on 537-Ser.
Yue C, Sanborn BM
Mol Cell Endocrinol. 2001
PubMed ID: 11325525
The sequence of the human genome.
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Science. 2001
PubMed ID: 11181995
The effects of aging on gene expression in the hypothalamus and cortex of mice.
Jiang CH, Tsien JZ, Schultz PG, Hu Y
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11172053
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein.
Wu X, McMurray CT
J Biol Chem. 2001
PubMed ID: 11013247
Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin.
Walikonis RS, Oguni A, Khorosheva EM, Jeng CJ, Asuncion FJ, Kennedy MB
J Neurosci. 2001
PubMed ID: 11160423
Ca(2+)/CaM-dependent kinases: from activation to function.
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Annu Rev Pharmacol Toxicol. 2001
PubMed ID: 11264466
Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease(1).
Sokal I, Li N, Verlinde CL, Haeseleer F, Baehr W, Palczewski K
Biochim Biophys Acta. 2000
PubMed ID: 11108966
delta Ca(2+)/Calmodulin-dependent protein kinase II isozyme-specific induction of neurite outgrowth in P19 embryonal carcinoma cells.
Johnson LD, Willoughby CA, Burke SH, Paik DS, Jenkins KJ, Tombes RM
J Neurochem. 2000
PubMed ID: 11080189
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II.
Wicks SJ, Lui S, Abdel-Wahab N, Mason RM, Chantry A
Mol Cell Biol. 2000
PubMed ID: 11027280
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2.
Goeckeler ZM, Masaracchia RA, Zeng Q, Chew TL, Gallagher P, Wysolmerski RB
J Biol Chem. 2000
PubMed ID: 10748018
Alternative splice variant of gamma-calmodulin-dependent protein kinase II alters activation by calmodulin.
Kwiatkowski AP, McGill JM
Arch Biochem Biophys. 2000
PubMed ID: 10860555
A role for CaMKII in T cell memory.
Bui JD, Calbo S, Hayden-Martinez K, Kane LP, Gardner P, Hedrick SM
Cell. 2000
PubMed ID: 10693762
Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.
Haeseleer F, Sokal I, Verlinde CL, Erdjument-Bromage H, Tempst P, Pronin AN, Benovic JL, Fariss RN, Palczewski K
J Biol Chem. 2000
PubMed ID: 10625670
Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.
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Mol Cell Biol. 1999
PubMed ID: 10373510
Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system.
Bayer KU, Löhler J, Schulman H, Harbers K
Brain Res Mol Brain Res. 1999
PubMed ID: 10381553
Characterization of phosphorylation sites on the glutamate receptor 4 subunit of the AMPA receptors.
Carvalho AL, Kameyama K, Huganir RL
J Neurosci. 1999
PubMed ID: 10366608
Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation.
Feinmesser RL, Wicks SJ, Taverner CJ, Chantry A
J Biol Chem. 1999
PubMed ID: 10347170
Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation.
Fleming IN, Elliott CM, Buchanan FG, Downes CP, Exton JH
J Biol Chem. 1999
PubMed ID: 10212259
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Calcium/calmodulin-dependent protein kinase II and calmodulin: regulators of the meiotic spindle in mouse eggs.
Johnson J, Bierle BM, Gallicano GI, Capco DG
Dev Biol. 1998
PubMed ID: 9882483
Phosphorylation and inhibition of olfactory adenylyl cyclase by CaM kinase II in Neurons: a mechanism for attenuation of olfactory signals.
Wei J, Zhao AZ, Chan GC, Baker LP, Impey S, Beavo JA, Storm DR
Neuron. 1998
PubMed ID: 9768837
Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro.
Kubes M, Cordier J, Glowinski J, Girault JA, Chneiweiss H
J Neurochem. 1998
PubMed ID: 9721757
Effects of phosphorylation on function of the Rad GTPase.
Moyers JS, Zhu J, Kahn CR
Biochem J. 1998
PubMed ID: 9677319
Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.
Wollmuth LP, Kuner T, Sakmann B
J Physiol. 1998
PubMed ID: 9481670
Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor.
Barria A, Derkach V, Soderling T
J Biol Chem. 1997
PubMed ID: 9407043
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S
Gene. 1997
PubMed ID: 9373149
Stat1 associates with c-kit and is activated in response to stem cell factor.
Deberry C, Mou S, Linnekin D
Biochem J. 1997
PubMed ID: 9355737
Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II.
Moyers JS, Bilan PJ, Zhu J, Kahn CR
J Biol Chem. 1997
PubMed ID: 9115241
Novel Ca2+/calmodulin-dependent protein kinase II gamma-subunit variants expressed in vascular smooth muscle, brain, and cardiomyocytes.
Singer HA, Benscoter HA, Schworer CM
J Biol Chem. 1997
PubMed ID: 9083077
Identification of novel human tumor cell-specific CaMK-II variants.
Tombes RM, Krystal GW
Biochim Biophys Acta. 1997
PubMed ID: 9060999
Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo.
Wei J, Wayman G, Storm DR
J Biol Chem. 1996
PubMed ID: 8798667
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein.
Shimomura A, Ogawa Y, Kitani T, Fujisawa H, Hagiwara M
J Biol Chem. 1996
PubMed ID: 8663317
Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cel
Williams CL, Phelps SH, Porter RA
Biochem Pharmacol. 1996
PubMed ID: 8615909
Human biliary epithelial cell line Mz-ChA-1 expresses new isoforms of calmodulin-dependent protein kinase II.
Kwiatkowski AP, McGill JM
Gastroenterology. 1995
PubMed ID: 7557101
Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.
Andersen DL, Tannenberg AE, Burke CJ, Dodd PR
Brain Res Dev Brain Res. 1995
PubMed ID: 8665664
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation.
Wen Z, Zhong Z, Darnell JE
Cell. 1995
PubMed ID: 7543024
Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity.
Zhu J, Reynet C, Caldwell JS, Kahn CR
J Biol Chem. 1995
PubMed ID: 7876254
Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors.
Yakel JL, Vissavajjhala P, Derkach VA, Brickey DA, Soderling TR
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7877986
New isoforms of Ca2+/calmodulin-dependent protein kinase II in smooth muscle.
Zhou ZL, Ikebe M
Biochem J. 1994
PubMed ID: 8172610
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
Maruyama K, Sugano S
Gene. 1994
PubMed ID: 8125298
Localization of the CAMKG gene encoding gamma isoforms of multifunctional calcium/calmodulin-dependent protein kinase (CaM kinase) to human chromosome 10 band q22 and mouse chromosome 14.
Li X, Nghiem P, Schulman H, Francke U
Cytogenet Cell Genet. 1994
PubMed ID: 8287681
Multiple and cooperative phosphorylation events regulate the CREM activator function.
de Groot RP, den Hertog J, Vandenheede JR, Goris J, Sassone-Corsi P
EMBO J. 1993
PubMed ID: 8404858
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma.
Shuai K, Stark GR, Kerr IM, Darnell JE
Science. 1993
PubMed ID: 7690989
Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues.
Nghiem P, Saati SM, Martens CL, Gardner P, Schulman H
J Biol Chem. 1993
PubMed ID: 8449910
Phosphorylation of serine 2843 in ryanodine receptor-calcium release channel of skeletal muscle by cAMP-, cGMP- and CaM-dependent protein kinase.
Suko J, Maurer-Fogy I, Plank B, Bertel O, Wyskovsky W, Hohenegger M, Hellmann G
Biochim Biophys Acta. 1993
PubMed ID: 8380342
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.
Countaway JL, Nairn AC, Davis RJ
J Biol Chem. 1992
PubMed ID: 1309762
Phosphorylation of smooth myosin light chain kinase by smooth muscle Ca2+/calmodulin-dependent multifunctional protein kinase.
Ikebe M, Reardon S
J Biol Chem. 1990
PubMed ID: 2160950
Molecular cloning of the cDNA encoding the third polypeptide (gamma) of brain calmodulin-dependent protein kinase II.
Tobimatsu T, Kameshita I, Fujisawa H
J Biol Chem. 1988
PubMed ID: 2846534
Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I.
Czernik AJ, Pang DT, Greengard P
Proc Natl Acad Sci U S A. 1987
PubMed ID: 3118371
Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase.
Vulliet PR, Woodgett JR, Cohen P
J Biol Chem. 1984
PubMed ID: 6150037

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	818	12325	171140
EnsEMBL Gene(s)	ENSG00000148660	ENSMUSG00000021820	ENSRNOG00000009783
Unigene	Hs.523045	Mm.235182	Rn.10961
Homologene	CAMK2G	Camk2g	Camk2g
OMIM	602123	N/A	N/A
GeneCards	CAMK2G	N/A	N/A
Beta Cell Genomics	DT.100674303 DT.100827661 DT.100885670 DT.116882 DT.121239498 DT.434248 DT.444370 DT.91752787 DT.91752791 DT.95180782 DT.95275517 DT.99984302	DT.101143928 DT.101337254 DT.101390072 DT.532494 DT.532555 DT.94275780	N/A
Reactome	Q13555	N/A	N/A
Plasma Peptide Atlas	ENSP00000277853	N/A	N/A
WikiGenes	818	12325	171140

External resources from NIDDK Consortium Interconnectivity Network Top Help

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View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
CAMK2G	USP19	IntAct, BioGRID	empirical	19615732
CAMK2G	MALT1	BioGRID	empirical	21513986
CAMK2G	ADCY3	HPRD	empirical	8798667 9768837
CAMK2G	CHAT	HPRD	empirical	12486117
CAMK2G	CREM	HPRD	empirical	8404858
CAMK2G	EGFR	HPRD	empirical	1309762 10347170
CAMK2G	FLNA	HPRD	empirical	11290523
CAMK2G	RCHY1	BioGRID	empirical	17568776
CAMK2G	GRIA1	HPRD	empirical	12609872 9407043 7877986
CAMK2G	GRIA4	HPRD	empirical	10366608
CAMK2G	GRIN2B	HPRD	empirical	16436603 16120608
CAMK2G	SMAD2	BioGRID	empirical	11027280
CAMK2G	SMAD3	HPRD	empirical	11027280
CAMK2G	SMAD4	HPRD, BioGRID	empirical	11027280
CAMK2G	MYLK	HPRD	empirical	10748018 2160950
CAMK2G	ATF1	HPRD	empirical	8663317
CAMK2G	CABP2	HPRD, BioGRID	empirical	10625670 11108966
CAMK2G	PLCB3	HPRD	empirical	11325525
CAMK2G	CABP5	BioGRID	empirical	10625670
CAMK2G	LRRC7	HPRD, BioGRID	empirical	16120608 11160423
CAMK2G	RRAD	HPRD	empirical	7876254 9677319
CAMK2G	RYR1	HPRD	empirical	8380342 14532276
CAMK2G	SLC2A4	IntAct	empirical	16396496
CAMK2G	SPR	HPRD	empirical	11825621
CAMK2G	STAT1	HPRD	empirical	11972023 7543024 9355737 14963018 11839738 15322115 7690989 12637327
CAMK2G	SYN1	HPRD	empirical	3118371
CAMK2G	TH	HPRD	empirical	6150037 11359875
CAMK2G	TIAM1	HPRD	empirical	10212259
CAMK2G	UBC	BioGRID	empirical	18781797 21139048 21906983
CAMK2G	YWHAB	IntAct	empirical	16635246
CAMK2G	CALM1	HPRD	empirical	10860555
CAMK2G	ACTN4	HPRD	empirical	11160423
CAMK2G	CAMK2A	Reactome	predicted	18218981 8615909
CAMK2G	CAMK2B	Reactome	predicted	18218981 8615909
CAMK2G	CAMK2G	HPRD	empirical	8449910
CAMK2G	PEA15	HPRD	empirical	12808093 9721757
CAMK2G	ACTN2	HPRD	empirical	16120608
CAMK2G	BCL10	BioGRID	empirical	21513986
CAMK2G	CABP1	BioGRID	empirical	10625670