SF3A2
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(Human) GRCh37 - chr19:2236816..2248678 (11.86 kb) View in Genome Browser
(Mouse) NCBIM37 - chr10:80260943..80267669 (6.73 kb) View in Genome Browser
(Rat) RGSC3.4 - chr7:10419996..10426019 (62 kb) View in Genome Browser
HaemAtlas Expression Table for SF3A2:
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
| no data | no data | |||||||||||
Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expression Legend
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for SF3A2:The SF3A2 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| SF3A2 | PQBP1 | MINT | empirical | 17332742 |
| SF3A2 | TRAP1 | BioGRID | empirical | 12234937 |
| SF3A2 | RBM5 | MINT | empirical | 17332742 |
| SF3A2 | HNRNPR | MINT | empirical | 17332742 |
| SF3A2 | SF3B4 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | SMNDC1 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | BCAS2 | MINT | empirical | 17332742 |
| SF3A2 | SF3A1 | HPRD, MINT, IntAct, BioGRID, Reactome, Sanger Interaction Map | empirical | 11533230 17332742 20360068 12234937 15345047 |
| SF3A2 | HMG20B | BioGRID | empirical | 12234937 |
| SF3A2 | CD2BP2 | MINT | empirical | 17332742 |
| SF3A2 | SYNCRIP | MINT | empirical | 17332742 |
| SF3A2 | DDX17 | MINT | empirical | 17332742 |
| SF3A2 | CHERP | MINT | empirical | 17332742 |
| SF3A2 | PRPF8 | MINT | empirical | 17332742 |
| SF3A2 | TCERG1 | MINT, BioGRID | empirical | 17332742 16055720 |
| SF3A2 | RNPS1 | MINT | empirical | 17332742 |
| SF3A2 | SF3A3 | MINT, BioGRID, Reactome | empirical | 17332742 12234937 |
| SF3A2 | SF3B2 | MINT, BioGRID, Sanger Interaction Map | empirical | 17332742 12234937 15345047 |
| SF3A2 | HNRNPUL1 | MINT | empirical | 17332742 |
| SF3A2 | WBP4 | MINT, BioGRID | empirical | 16055720 |
| SF3A2 | CHM | IntAct | empirical | 19615732 |
| SF3A2 | DDX42 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | U2AF2 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | CIRBP | MINT | empirical | 17332742 |
| SF3A2 | ZC3H18 | MINT | empirical | 17332742 |
| SF3A2 | DDX5 | MINT | empirical | 17332742 |
| SF3A2 | DHX9 | MINT | empirical | 17332742 |
| SF3A2 | DHX15 | MINT | empirical | 17332742 |
| SF3A2 | ELAVL1 | MINT | empirical | 17332742 |
| SF3A2 | HNRNPA3 | MINT | empirical | 17332742 |
| SF3A2 | DNAJC8 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | PUF60 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | NCBP2 | MINT | empirical | 17332742 |
| SF3A2 | ACIN1 | MINT | empirical | 17332742 |
| SF3A2 | SNRNP200 | MINT | empirical | 17332742 |
| SF3A2 | U2SURP | BioGRID | empirical | 12234937 |
| SF3A2 | SF3B3 | MINT | empirical | 17332742 |
| SF3A2 | SF3B1 | MINT, BioGRID, Sanger Interaction Map | empirical | 17332742 12234937 15345047 |
| SF3A2 | SRRM2 | MINT | empirical | 17332742 |
| SF3A2 | PRPF6 | MINT | empirical | 17332742 |
| SF3A2 | FUS | MINT | empirical | 17332742 |
| SF3A2 | SEC31B | MINT | empirical | 17332742 |
| SF3A2 | RBMX | MINT | empirical | 17332742 |
| SF3A2 | HTATSF1 | HPRD, MINT, BioGRID | empirical | 9710584 17332742 |
| SF3A2 | PRPF19 | MINT | empirical | 17332742 |
| SF3A2 | C16orf80 | MINT | empirical | 17332742 |
| SF3A2 | SAP30BP | MINT | empirical | 17332742 |
| SF3A2 | HNRNPA1 | MINT | empirical | 17332742 |
| SF3A2 | HNRNPA2B1 | MINT | empirical | 17332742 |
| SF3A2 | HNRNPAB | MINT | empirical | 17332742 |
| SF3A2 | HNRNPC | MINT | empirical | 17332742 |
| SF3A2 | HNRNPK | MINT | empirical | 17332742 |
| SF3A2 | HNRNPU | MINT | empirical | 17332742 |
| SF3A2 | APBB1 | BioGRID | empirical | 16055720 |
| SF3A2 | HSPA8 | MINT | empirical | 17332742 |
| SF3A2 | HSPD1 | BioGRID | empirical | 12234937 |
| SF3A2 | ILF2 | MINT | empirical | 17332742 |
| SF3A2 | ILF3 | MINT | empirical | 17332742 |
| SF3A2 | NCBP1 | MINT | empirical | 17332742 |
| SF3A2 | YBX1 | MINT | empirical | 17332742 |
| SF3A2 | PCBP1 | MINT | empirical | 17332742 |
| SF3A2 | CWC15 | MINT | empirical | 17332742 |
| SF3A2 | SRRT | MINT | empirical | 17332742 |
| SF3A2 | SF3B14 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | WBP11 | MINT | empirical | 17332742 |
| SF3A2 | PLRG1 | MINT | empirical | 17332742 |
| SF3A2 | PNN | MINT | empirical | 17332742 |
| SF3A2 | PPP1CA | MINT | empirical | 17332742 |
| SF3A2 | ARGLU1 | MINT | empirical | 17332742 |
| SF3A2 | AGGF1 | MINT | empirical | 17332742 |
| SF3A2 | PPP1R8 | MINT | empirical | 17332742 |
| SF3A2 | PRCC | MINT | empirical | 17332742 |
| SF3A2 | PRPF40A | MINT, BioGRID | empirical | 17332742 16055720 |
| SF3A2 | CCAR1 | MINT | empirical | 17332742 |
| SF3A2 | CTNNBL1 | MINT | empirical | 17332742 |
| SF3A2 | RETN | HPRD | empirical | 8211113 |
| SF3A2 | SUGP1 | MINT | empirical | 17332742 |
| SF3A2 | KIAA1967 | MINT | empirical | 17332742 |
| SF3A2 | RBM25 | MINT | empirical | 17332742 |
| SF3A2 | SRSF1 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | SRSF2 | MINT | empirical | 17332742 |
| SF3A2 | SRSF3 | MINT | empirical | 17332742 |
| SF3A2 | SRSF4 | MINT | empirical | 17332742 |
| SF3A2 | SRSF5 | MINT | empirical | 17332742 |
| SF3A2 | SRSF6 | MINT | empirical | 17332742 |
| SF3A2 | SRSF7 | MINT | empirical | 17332742 |
| SF3A2 | TRA2B | MINT | empirical | 17332742 |
| SF3A2 | SMURF2 | HPRD, MINT | empirical | 15231748 |
| SF3A2 | SNRNP70 | MINT | empirical | 17332742 |
| SF3A2 | SNRPA | MINT | empirical | 17332742 |
| SF3A2 | SNRPA1 | MINT, BioGRID, Sanger Interaction Map | empirical | 17332742 12234937 15345047 |
| SF3A2 | SNRPB | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | SNRPB2 | MINT | empirical | 17332742 |
| SF3A2 | SNRPC | MINT | empirical | 17332742 |
| SF3A2 | SNRPD1 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | SNRPD2 | MINT | empirical | 17332742 |
| SF3A2 | SNRPD3 | MINT, BioGRID, Sanger Interaction Map | empirical | 17332742 12234937 15345047 |
| SF3A2 | SNRPE | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | SNRPF | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | SNRPG | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | KLF5 | Sanger Interaction Map | predicted | 15345047 |
| SF3A2 | U2AF1 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | UBC | BioGRID | empirical | 21139048 21890473 21906983 |
| SF3A2 | SF1 | MINT | empirical | 17332742 |
| SF3A2 | ZNF207 | MINT | empirical | 17332742 |
| SF3A2 | C19orf43 | MINT | empirical | 17332742 |
| SF3A2 | SF3A2 | MINT | empirical | 17332742 |
| SF3A2 | RBM10 | MINT | empirical | 17332742 |
| SF3A2 | SF3B5 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | NRIP2 | MINT | empirical | 17332742 |
| SF3A2 | RAE1 | BioGRID | empirical | 19615732 |
| SF3A2 | PHF5A | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | RBM17 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | USP45 | IntAct, BioGRID | empirical | 19615732 |
| SF3A2 | SRSF9 | MINT | empirical | 17332742 |
| SF3A2 | SART1 | MINT | empirical | 17332742 |
| SF3A2 | PRPF3 | MINT | empirical | 17332742 |
| SF3A2 | BUB3 | MINT | empirical | 17332742 |
| SF3A2 | EFTUD2 | MINT | empirical | 17332742 |
| SF3A2 | DDX23 | MINT | empirical | 17332742 |
| SF3A2 | RBM39 | MINT | empirical | 17332742 |
| SF3A2 | DDX46 | MINT, BioGRID | empirical | 17332742 12234937 |
| SF3A2 | CDC5L | MINT | empirical | 17332742 |
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Publications: 48
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A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
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Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
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Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
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Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM
Science. 2010
PubMed ID: 20360068
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Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell. 2009
PubMed ID: 19615732
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Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
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A WW-like module in the RAG1 N-terminal domain contributes to previously unidentified protein-protein interactions.
Maitra R, Sadofsky MJ
Nucleic Acids Res. 2009
PubMed ID: 19324890
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Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
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Minor spliceosome components are predominantly localized in the nucleus.
Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Perälä N, Nymark M, Turunen JJ, Lührmann R, Frilander MJ
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18559850
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GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
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EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W
Brief Funct Genomic Proteomic. 2007
PubMed ID: 17967808
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Broad spectrum identification of SUMO substrates in melanoma cells.
Ganesan AK, Kho Y, Kim SC, Chen Y, Zhao Y, White MA
Proteomics. 2007
PubMed ID: 17549794
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
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WW domains provide a platform for the assembly of multiprotein networks.
Ingham RJ, Colwill K, Howard C, Dettwiler S, Lim CS, Yu J, Hersi K, Raaijmakers J, Gish G, Mbamalu G, Taylor L, Yeung B, Vassilovski G, Amin M, Chen F, Matskova L, Winberg G, Ernberg I, Linding R, O'donnell P, Starostine A, Keller W, Metalnikov P, Stark C, Pawson T
Mol Cell Biol. 2005
PubMed ID: 16055720
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Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.
Tanackovic G, Krämer A
Mol Biol Cell. 2005
PubMed ID: 15647371
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Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
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A role for Cajal bodies in the final steps of U2 snRNP biogenesis.
Nesic D, Tanackovic G, Krämer A
J Cell Sci. 2004
PubMed ID: 15316075
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The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein.
Takenaka K, Nakagawa H, Miyamoto S, Miki H
Biochem J. 2004
PubMed ID: 15142036
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Functional proteomics mapping of a human signaling pathway.
Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM
Genome Res. 2004
PubMed ID: 15231748
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The DNA sequence and biology of human chromosome 19.
Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM
Nature. 2004
PubMed ID: 15057824
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
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BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein.
Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Lührmann R
EMBO J. 2002
PubMed ID: 12234937
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Comprehensive proteomic analysis of the human spliceosome.
Zhou Z, Licklider LJ, Gygi SP, Reed R
Nature. 2002
PubMed ID: 12226669
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A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.
Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD
Science. 2002
PubMed ID: 12040188
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Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ
RNA. 2002
PubMed ID: 11991638
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An expressed GNRP-like gene shares a bi-directional promoter with SF3A2 (SAP62) immediately upstream of AMH.
Dresser DW, Jamin SP, Atkins CJ, Guerrier D
Gene. 2001
PubMed ID: 11602354
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Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation.
Nesic D, Krämer A
Mol Cell Biol. 2001
PubMed ID: 11533230
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A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
Will CL, Schneider C, MacMillan AM, Katopodis NF, Neubauer G, Wilm M, Lührmann R, Query CC
EMBO J. 2001
PubMed ID: 11500380
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Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.
Puttagunta R, Gordon LA, Meyer GE, Kapfhamer D, Lamerdin JE, Kantheti P, Portman KM, Chung WK, Jenne DE, Olsen AS, Burmeister M
Genome Res. 2000
PubMed ID: 10984455
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Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
-
Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.
Das R, Zhou Z, Reed R
Mol Cell. 2000
PubMed ID: 10882114
-
Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP.
Krämer A, Grüter P, Gröning K, Kastner B
J Cell Biol. 1999
PubMed ID: 10385517
-
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.
Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M
Nat Genet. 1998
PubMed ID: 9731529
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CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif.
Yan D, Perriman R, Igel H, Howe KJ, Neville M, Ares M
Mol Cell Biol. 1998
PubMed ID: 9710584
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Structural/functional properties of a mammalian multi-component structure containing all major spliceosomal small nuclear ribonucleoprotein particles.
Moraitou M, Patrinou-Georgoula M, Guialis A
Biochem J. 1998
PubMed ID: 9576861
-
Association of U2 snRNP with the spliceosomal complex E.
Hong W, Bennett M, Xiao Y, Feld Kramer R, Wang C, Reed R
Nucleic Acids Res. 1997
PubMed ID: 9016565
-
Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes.
Odorisio T, Mahadevaiah SK, McCarrey JR, Burgoyne PS
Dev Biol. 1996
PubMed ID: 8948595
-
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
-
Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution.
Rain JC, Tartakoff AM, Krämer A, Legrain P
RNA. 1996
PubMed ID: 8718683
-
Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function.
Swain A, Zanaria E, Hacker A, Lovell-Badge R, Camerino G
Nat Genet. 1996
PubMed ID: 8630494
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The genes for a spliceosome protein (SAP62) and the anti-Müllerian hormone (AMH) are contiguous.
Dresser DW, Hacker A, Lovell-Badge R, Guerrier D
Hum Mol Genet. 1995
PubMed ID: 8541848
-
Correspondence between a mammalian spliceosome component and an essential yeast splicing factor.
Bennett M, Reed R
Science. 1993
PubMed ID: 8211113
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