Home CALR
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(Human) GRCh37 - chr19:13049414..13055304 (5.89 kb) View in Genome Browser
(Mouse) NCBIM37 - chr8:87365749..87370833 (58 kb) View in Genome Browser
(Rat) RGSC3.4 - chr19:24964775..24969670 (4.89 kb) View in Genome Browser
HaemAtlas Expression Table for CALR:|
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
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Expression Legend
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for CALR:The CALR interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| CALR | ARPC2 | Sanger Interaction Map | predicted | 15345047 |
| CALR | EIF1B | IntAct | empirical | 17353931 |
| CALR | GABARAP | IntAct | empirical | 20562859 |
| CALR | GABARAPL2 | IntAct | empirical | 20562859 |
| CALR | ELF3 | IntAct, BioGRID | empirical | 17353931 |
| CALR | EPB41 | IntAct, BioGRID | empirical | 17353931 |
| CALR | F5 | HPRD, BioGRID | empirical | 9525969 |
| CALR | F8 | HPRD | empirical | 9525969 |
| CALR | ACSL1 | IntAct | empirical | 20391537 |
| CALR | FBN1 | HPRD | empirical | 10547375 |
| CALR | FGB | HPRD, BioGRID | empirical | 7592883 |
| CALR | GABARAPL1 | IntAct | empirical | 20562859 |
| CALR | NR3C1 | HPRD, BioGRID | empirical | 8107808 9089287 |
| CALR | PDIA3 | HPRD, MINT, BioGRID, Reactome | empirical | 10436013 |
| CALR | H2AFX | IntAct, BioGRID | empirical | 20000738 16522924 |
| CALR | HLA-C | HPRD | empirical | 8769474 |
| CALR | APOB | HPRD, BioGRID | empirical | 10513896 12397072 |
| CALR | APP | HPRD, IntAct, BioGRID | empirical | 11378243 17934213 15896298 |
| CALR | AR | HPRD | empirical | 8107809 |
| CALR | ITGA2B | HPRD | empirical | 14985176 |
| CALR | ITGA3 | HPRD | empirical | 8006073 11327697 |
| CALR | ITGA5 | BioGRID | empirical | 12196561 |
| CALR | ITGAV | HPRD, BioGRID | empirical | 12196561 |
| CALR | KCNMA1 | IntAct | empirical | 19423573 |
| CALR | SUMO4 | HPRD | empirical | 16236267 |
| CALR | LCK | MINT | empirical | |
| CALR | LPL | HPRD | empirical | 12740382 |
| CALR | LRP1 | HPRD, BioGRID | empirical | 14980518 12821648 |
| CALR | MBL2 | HPRD | empirical | 8062452 |
| CALR | MTNR1A | HPRD, IntAct | empirical | 17215244 |
| CALR | NCK1 | IntAct | empirical | 15102471 |
| CALR | PAK2 | IntAct | empirical | 17353931 |
| CALR | PLAT | HPRD, BioGRID | empirical | 9359841 |
| CALR | PLP1 | HPRD | empirical | 12196561 |
| CALR | WDR74 | Sanger Interaction Map | predicted | 15345047 |
| CALR | PRF1 | HPRD | empirical | 9671507 |
| CALR | MAPK6 | BioGRID | empirical | 21900206 |
| CALR | B2M | HPRD | empirical | 8769474 |
| CALR | PSMA3 | BioGRID | empirical | 22079093 |
| CALR | ACTA1 | IntAct | empirical | 17205597 |
| CALR | RAN | Sanger Interaction Map | predicted | 15345047 |
| CALR | PDIA2 | HPRD | empirical | 8537405 |
| CALR | SLC2A1 | HPRD | empirical | 8662691 |
| CALR | SLC2A4 | IntAct | empirical | 16396496 |
| CALR | SLC6A4 | HPRD | empirical | 10364189 |
| CALR | SMARCB1 | BioGRID | empirical | 21900206 |
| CALR | TAP1 | IntAct | empirical | 17055437 |
| CALR | TAPBP | HPRD, BioGRID, Reactome | empirical | 8769474 16465444 15286279 19361863 19119025 19426129 14718384 |
| CALR | TF | HPRD, BioGRID | empirical | 9312001 |
| CALR | THBS1 | HPRD | empirical | 12147682 |
| CALR | NKX2-1 | HPRD | empirical | 9988700 |
| CALR | ACTG1 | IntAct | empirical | 17205597 |
| CALR | TRAF6 | IntAct | empirical | 17353931 15102471 |
| CALR | TSHR | HPRD | empirical | 12383251 |
| CALR | UBC | BioGRID | empirical | 21139048 21890473 21906983 |
| CALR | VWF | HPRD, BioGRID | empirical | 10887119 |
| CALR | YWHAZ | MINT | empirical | 15161933 |
| CALR | CALR | HPRD | empirical | 8910335 9036970 |
| CALR | CANX | BioGRID, Reactome | empirical | 10436013 |
| CALR | C11orf68 | IntAct, BioGRID | empirical | 20360068 |
| CALR | SCARF1 | HPRD | empirical | 15371419 |
| CALR | TNFRSF10D | IntAct | empirical | 17353931 |
| CALR | CD1D | HPRD | empirical | 12239218 |
| CALR | CD40 | IntAct, BioGRID | empirical | 17353931 |
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Type 1 Diabetes Publications: 2
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Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry.
Ahmed M, Forsberg J, Bergsten P
J Proteome Res. 2005
PubMed ID: 15952740
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Cloning and expression of secretagogin, a novel neuroendocrine- and pancreatic islet of Langerhans-specific Ca2+-binding protein.
Wagner L, Oliyarnyk O, Gartner W, Nowotny P, Groeger M, Kaserer K, Waldhäusl W, Pasternack MS
J Biol Chem. 2000
PubMed ID: 10811645
Publications: 310
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Enolase 1 and calreticulin regulate the differentiation and function of mouse mast cells.
Ryu SY, Hong GU, Kim DY, Ro JY
Cell Signal. 2012
PubMed ID: 21803152
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Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism.
Fedorova OA, Moiseeva TN, Nikiforov AA, Tsimokha AS, Livinskaya VA, Hodson M, Bottrill A, Evteeva IN, Ermolayeva JB, Kuznetzova IM, Turoverov KK, Eperon I, Barlev NA
Biochem Biophys Res Commun. 2011
PubMed ID: 22079093
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Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors.
Dey S, Matsunami H
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21933956
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Involvement of damage-associated molecular patterns in tumor response to photodynamic therapy: surface expression of calreticulin and high-mobility group box-1 release.
Korbelik M, Zhang W, Merchant S
Cancer Immunol Immunother. 2011
PubMed ID: 21644033
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A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE
Sci Signal. 2011
PubMed ID: 21900206
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Support for down-tuning of the calreticulin gene in the process of human evolution.
Esmaeilzadeh-Gharehdaghi E, Banan M, Farashi S, Mirabzadeh A, Farokhashtiani T, Hosseinkhani S, Heidari A, Najmabadi H, Ohadi M
Prog Neuropsychopharmacol Biol Psychiatry. 2011
PubMed ID: 21723904
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Structural and functional relationships between the lectin and arm domains of calreticulin.
Pocanschi CL, Kozlov G, Brockmeier U, Brockmeier A, Williams DB, Gehring K
J Biol Chem. 2011
PubMed ID: 21652723
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Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development.
del Barco Barrantes I, Coya JM, Maina F, Arthur JS, Nebreda AR
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21768366
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Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cells.
Peters LR, Raghavan M
J Immunol. 2011
PubMed ID: 21670312
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The interactions of calreticulin with immunoglobulin G and immunoglobulin Y.
Møllegaard KM, Duus K, Træholt SD, Thaysen-Andersen M, Liu Y, Palma AS, Feizi T, Hansen PR, Højrup P, Houen G
Biochim Biophys Acta. 2011
PubMed ID: 21447409
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Cell surface targeting of myelin oligodendrocyte glycoprotein (MOG) in the absence of endoplasmic reticulum molecular chaperones.
Jung J, Michalak M
Biochim Biophys Acta. 2011
PubMed ID: 21172390
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Reversion of the human calreticulin gene promoter to the ancestral type as a result of a novel psychosis-associated mutation.
Farokhashtiani T, Mirabzadeh A, Olad Nabi M, Magham ZG, Khorshid HR, Najmabadi H, Ohadi M
Prog Neuropsychopharmacol Biol Psychiatry. 2011
PubMed ID: 21182888
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Calreticulin is a thermostable protein with distinct structural responses to different divalent cation environments.
Wijeyesakere SJ, Gafni AA, Raghavan M
J Biol Chem. 2011
PubMed ID: 21177861
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Molecular and structural insight into the role of key residues of thrombospondin-1 and calreticulin in thrombospondin-1-calreticulin binding.
Yan Q, Murphy-Ullrich JE, Song Y
Biochemistry. 2011
PubMed ID: 21142150
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Biochemical and ultrastructural correlations of calreticulin and thioredoxin expression in breast mucinous carcinoma and infiltrating ductal carcinoma non-special type.
Baltatzis GE, Gaitanarou H, Arnogianaki N, Misitzis J, Voloudakis-Baltatzis IE
Ultrastruct Pathol. 2011
PubMed ID: 20929309
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The polypeptide binding conformation of calreticulin facilitates its cell-surface expression under conditions of endoplasmic reticulum stress.
Jeffery E, Peters LR, Raghavan M
J Biol Chem. 2011
PubMed ID: 21075854
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X-ray structure of the human calreticulin globular domain reveals a peptide-binding area and suggests a multi-molecular mechanism.
Chouquet A, Païdassi H, Ling WL, Frachet P, Houen G, Arlaud GJ, Gaboriaud C
PLoS One. 2011
PubMed ID: 21423620
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Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
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Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention.
Taner SB, Pando MJ, Roberts A, Schellekens J, Marsh SG, Malmberg KJ, Parham P, Brodsky FM
J Immunol. 2011
PubMed ID: 21115737
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Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47.
Chao MP, Jaiswal S, Weissman-Tsukamoto R, Alizadeh AA, Gentles AJ, Volkmer J, Weiskopf K, Willingham SB, Raveh T, Park CY, Majeti R, Weissman IL
Sci Transl Med. 2010
PubMed ID: 21178137
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Structural basis of carbohydrate recognition by calreticulin.
Kozlov G, Pocanschi CL, Rosenauer A, Bastos-Aristizabal S, Gorelik A, Williams DB, Gehring K
J Biol Chem. 2010
PubMed ID: 20880849
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Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum.
Zhu Y, Zhang W, Veerapen N, Besra G, Cresswell P
J Biol Chem. 2010
PubMed ID: 20861015
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Clinicopathological significance of calreticulin in breast invasive ductal carcinoma.
Lwin ZM, Guo C, Salim A, Yip GW, Chew FT, Nan J, Thike AA, Tan PH, Bay BH
Mod Pathol. 2010
PubMed ID: 20834237
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Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease.
Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, Liu X, Sun L, Lv P, Gao XM
J Immunol. 2010
PubMed ID: 20855873
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The calreticulin-binding sequence of thrombospondin 1 regulates collagen expression and organization during tissue remodeling.
Sweetwyne MT, Pallero MA, Lu A, Van Duyn Graham L, Murphy-Ullrich JE
Am J Pathol. 2010
PubMed ID: 20724603
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Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
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Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells.
Tarr JM, Winyard PG, Ryan B, Harries LW, Haigh R, Viner N, Eggleton P
Arthritis Rheum. 2010
PubMed ID: 20533543
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A mechanism of release of calreticulin from cells during apoptosis.
Tarr JM, Young PJ, Morse R, Shaw DJ, Haigh R, Petrov PG, Johnson SJ, Winyard PG, Eggleton P
J Mol Biol. 2010
PubMed ID: 20624402
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Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death.
Kepp O, Gdoura A, Martins I, Panaretakis T, Schlemmer F, Tesniere A, Fimia GM, Ciccosanti F, Burgevin A, Piacentini M, Eggleton P, Young PJ, Zitvogel L, van Endert P, Kroemer G
Cell Cycle. 2010
PubMed ID: 20699648
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Decoded calreticulin-deficient embryonic stem cell transcriptome resolves latent cardiophenotype.
Faustino RS, Chiriac A, Niederlander NJ, Nelson TJ, Behfar A, Mishra PK, Macura S, Michalak M, Terzic A, Perez-Terzic C
Stem Cells. 2010
PubMed ID: 20506533
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Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.
Vuppalanchi D, Coleman J, Yoo S, Merianda TT, Yadhati AG, Hossain J, Blesch A, Willis DE, Twiss JL
J Biol Chem. 2010
PubMed ID: 20308067
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The arginylation-dependent association of calreticulin with stress granules is regulated by calcium.
Carpio MA, López Sambrooks C, Durand ES, Hallak ME
Biochem J. 2010
PubMed ID: 20423325
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Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia.
Schardt JA, Eyholzer M, Timchenko NA, Mueller BU, Pabst T
J Cell Mol Med. 2010
PubMed ID: 19659458
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Expression of calreticulin is associated with infiltration of T-cells in stage IIIB colon cancer.
Peng RQ, Chen YB, Ding Y, Zhang R, Zhang X, Yu XJ, Zhou ZW, Zeng YX, Zhang XS
World J Gastroenterol. 2010
PubMed ID: 20480531
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Ovalbumin-derived precursor peptides are transferred sequentially from gp96 and calreticulin to MHC class I in the endoplasmic reticulum.
Kropp LE, Garg M, Binder RJ
J Immunol. 2010
PubMed ID: 20410492
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Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM
Science. 2010
PubMed ID: 20360068
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Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix.
Van Duyn Graham L, Sweetwyne MT, Pallero MA, Murphy-Ullrich JE
J Biol Chem. 2010
PubMed ID: 20044481
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Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Yang X, Zou P, Yao J, Yun D, Bao H, Du R, Long J, Chen X
J Proteome Res. 2010
PubMed ID: 20000738
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Novel mutations in the calreticulin gene core promoter and coding sequence in schizoaffective disorder.
Nabi MO, Mirabzadeh A, Feizzadeh G, Khorshid HR, Karimlou M, Yeganeh MZ, Asgharian AM, Najmabadi H, Ohadi M
Am J Med Genet B Neuropsychiatr Genet. 2010
PubMed ID: 19760677
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Evidence for calreticulin attenuation of cardiac hypertrophy induced by pressure overload and soluble agonists.
Papp S, Dziak E, Kabir G, Backx P, Clement S, Opas M
Am J Pathol. 2010
PubMed ID: 20110410
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Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
Jungwirth M, Dear ML, Brown P, Holbrook K, Goodchild R
Hum Mol Genet. 2010
PubMed ID: 20015956
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Modes of calreticulin recruitment to the major histocompatibility complex class I assembly pathway.
Del Cid N, Jeffery E, Rizvi SM, Stamper E, Peters LR, Brown WC, Provoda C, Raghavan M
J Biol Chem. 2010
PubMed ID: 19959473
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The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.
Hryciw T, MacDonald JI, Phillips R, Seah C, Pasternak S, Meakin SO
J Neurochem. 2010
PubMed ID: 19943849
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Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210.
Smits P, Bolton AD, Funari V, Hong M, Boyden ED, Lu L, Manning DK, Dwyer ND, Moran JL, Prysak M, Merriman B, Nelson SF, Bonafé L, Superti-Furga A, Ikegawa S, Krakow D, Cohn DH, Kirchhausen T, Warman ML, Beier DR
N Engl J Med. 2010
PubMed ID: 20089971
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Identification of the rheumatoid arthritis shared epitope binding site on calreticulin.
Ling S, Cheng A, Pumpens P, Michalak M, Holoshitz J
PLoS One. 2010
PubMed ID: 20661469
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Selective preservation of bone marrow mature recirculating but not marginal zone B cells in murine models of chronic inflammation.
Traggiai E, Casati A, Frascoli M, Porcellini S, Ponzoni M, Sanvito F, Leng L, Bucala R, Moretta L, Grassi F
PLoS One. 2010
PubMed ID: 20582316
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Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.
Mao C, Wang M, Luo B, Wey S, Dong D, Wesselschmidt R, Rawlings S, Lee AS
PLoS One. 2010
PubMed ID: 20520781
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Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules.
Howe C, Garstka M, Al-Balushi M, Ghanem E, Antoniou AN, Fritzsche S, Jankevicius G, Kontouli N, Schneeweiss C, Williams A, Elliott T, Springer S
EMBO J. 2009
PubMed ID: 19851281
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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
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Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma.
Du XL, Yang H, Liu SG, Luo ML, Hao JJ, Zhang Y, Lin DC, Xu X, Cai Y, Zhan QM, Wang MR
Oncogene. 2009
PubMed ID: 19684620
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Calreticulin maintains the low threshold of peptide required for efficient antigen presentation.
Fu H, Liu C, Flutter B, Tao H, Gao B
Mol Immunol. 2009
PubMed ID: 19748124
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Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins.
Sato H, Azuma Y, Higai K, Matsumoto K
Biochim Biophys Acta. 2009
PubMed ID: 19524015
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Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization.
Abd Alla J, Reeck K, Langer A, Streichert T, Quitterer U
Biochem Biophys Res Commun. 2009
PubMed ID: 19580784
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Cell adhesion and spreading affect adipogenesis from embryonic stem cells: the role of calreticulin.
Szabo E, Feng T, Dziak E, Opas M
Stem Cells. 2009
PubMed ID: 19544411
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Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
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Suppressive roles of calreticulin in prostate cancer growth and metastasis.
Alur M, Nguyen MM, Eggener SE, Jiang F, Dadras SS, Stern J, Kimm S, Roehl K, Kozlowski J, Pins M, Michalak M, Dhir R, Wang Z
Am J Pathol. 2009
PubMed ID: 19608864
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Congenital heart block not associated with anti-Ro/La antibodies: comparison with anti-Ro/La-positive cases.
Brucato A, Grava C, Bortolati M, Ikeda K, Milanesi O, Cimaz R, Ramoni V, Vignati G, Martinelli S, Sadou Y, Borghi A, Tincani A, Chan EK, Ruffatti A
J Rheumatol. 2009
PubMed ID: 19567621
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Embryonic stem cell-derived cardiomyogenesis: a novel role for calreticulin as a regulator.
Papp S, Dziak E, Opas M
Stem Cells. 2009
PubMed ID: 19544459
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Protein processing by the placental protease, cathepsin P.
Hassanein M, Bojja AS, Glazewski L, Lu G, Mason RW
Mol Hum Reprod. 2009
PubMed ID: 19346238
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Activation of the unfolded protein response is associated with favorable prognosis in acute myeloid leukemia.
Schardt JA, Weber D, Eyholzer M, Mueller BU, Pabst T
Clin Cancer Res. 2009
PubMed ID: 19470730
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Autoacetylation of purified calreticulin transacetylase utilizing acetoxycoumarin as the acetyl group donor.
Bansal S, Ponnan P, Raj HG, Weintraub ST, Chopra M, Kumari R, Saluja D, Kumar A, Tyagi TK, Singh P, Prasad AK, Saso L, Rastogi RC, Parmar VS
Appl Biochem Biotechnol. 2009
PubMed ID: 18795239
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In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12I protein.
Fukumoto R, Andresen V, Bialuk I, Cecchinato V, Walser JC, Valeri VW, Nauroth JM, Gessain A, Nicot C, Franchini G
Blood. 2009
PubMed ID: 18791162
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Calreticulin mediated glucocorticoid receptor export is involved in beta-catenin translocation and Wnt signalling inhibition in human osteoblastic cells.
Olkku A, Mahonen A
Bone. 2009
PubMed ID: 19100874
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Effects of humoral immunity and calreticulin overexpression on postoperative course in breast cancer.
Erić A, Juranić Z, Milovanović Z, Marković I, Inić M, Stanojević-Bakić N, Vojinović-Golubović V
Pathol Oncol Res. 2009
PubMed ID: 18925427
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Transcriptional control of the calreticulin gene in health and disease.
Qiu Y, Michalak M
Int J Biochem Cell Biol. 2009
PubMed ID: 18765291
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Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
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Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones.
Thielmann Y, Weiergräber OH, Mohrlüder J, Willbold D
FEBS J. 2009
PubMed ID: 19154346
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Identification of calreticulin as a prognosis marker and angiogenic regulator in human gastric cancer.
Chen CN, Chang CC, Su TE, Hsu WM, Jeng YM, Ho MC, Hsieh FJ, Lee PH, Kuo ML, Lee H, Chang KJ
Ann Surg Oncol. 2009
PubMed ID: 19050968
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Substrate specificity of the oxidoreductase ERp57 is determined primarily by its interaction with calnexin and calreticulin.
Jessop CE, Tavender TJ, Watkins RH, Chambers JE, Bulleid NJ
J Biol Chem. 2009
PubMed ID: 19054761
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Human protein factory for converting the transcriptome into an in vitro-expressed proteome,.
Goshima N, Kawamura Y, Fukumoto A, Miura A, Honma R, Satoh R, Wakamatsu A, Yamamoto J, Kimura K, Nishikawa T, Andoh T, Iida Y, Ishikawa K, Ito E, Kagawa N, Kaminaga C, Kanehori K, Kawakami B, Kenmochi K, Kimura R, Kobayashi M, Kuroita T, Kuwayama H, Maruyama Y, Matsuo K, Minami K, Mitsubori M, Mori M, Morishita R, Murase A, Nishikawa A, Nishikawa S, Okamoto T, Sakagami N, Sakamoto Y, Sasaki Y, Seki T, Sono S, Sugiyama A, Sumiya T, Takayama T, Takayama Y, Takeda H, Togashi T, Yahata K, Yamada H, Yanagisawa Y, Endo Y, Imamoto F, Kisu Y, Tanaka S, Isogai T, Imai J, Watanabe S, Nomura N
Nat Methods. 2008
PubMed ID: 19054851
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Calreticulin regulates insulin receptor expression and its downstream PI3 Kinase/Akt signalling pathway.
Jalali S, Aghasi M, Yeganeh B, Mesaeli N
Biochim Biophys Acta. 2008
PubMed ID: 18840478
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A mutation in the calreticulin gene promoter in a family case of schizoaffective disorder leads to its aberrant transcriptional activation.
Nunes A, Ohadi M, Rahimi A, Aghajani A, Najmabadi H, Currais A, Soriano S
Brain Res. 2008
PubMed ID: 18801343
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Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis.
Pallero MA, Elzie CA, Chen J, Mosher DF, Murphy-Ullrich JE
FASEB J. 2008
PubMed ID: 18653767
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
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Thyroid hormone receptor alpha1 follows a cooperative CRM1/calreticulin-mediated nuclear export pathway.
Grespin ME, Bonamy GM, Roggero VR, Cameron NG, Adam LE, Atchison AP, Fratto VM, Allison LA
J Biol Chem. 2008
PubMed ID: 18641393
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Small angle X-ray scattering study of calreticulin reveals conformational plasticity.
Nørgaard Toft K, Larsen N, Steen Jørgensen F, Højrup P, Houen G, Vestergaard B
Biochim Biophys Acta. 2008
PubMed ID: 18559259
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The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Panaretakis T, Joza N, Modjtahedi N, Tesniere A, Vitale I, Durchschlag M, Fimia GM, Kepp O, Piacentini M, Froehlich KU, van Endert P, Zitvogel L, Madeo F, Kroemer G
Cell Death Differ. 2008
PubMed ID: 18464797
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ERP57 membrane translocation dictates the immunogenicity of tumor cell death by controlling the membrane translocation of calreticulin.
Obeid M
J Immunol. 2008
PubMed ID: 18684944
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Calreticulin inhibits commitment to adipocyte differentiation.
Szabo E, Qiu Y, Baksh S, Michalak M, Opas M
J Cell Biol. 2008
PubMed ID: 18606846
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Differential phosphorylation of calreticulin affects AT1 receptor mRNA stability in VSMC.
Mueller CF, Wassmann K, Berger A, Holz S, Wassmann S, Nickenig G
Biochem Biophys Res Commun. 2008
PubMed ID: 18413143
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Altered expression of calreticulin during the development of fibrosis.
Kypreou KP, Kavvadas P, Karamessinis P, Peroulis M, Alberti A, Sideras P, Psarras S, Capetanaki Y, Politis PK, Charonis AS
Proteomics. 2008
PubMed ID: 18563736
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Enhanced ubiquitin-proteasome activity in calreticulin deficient cells: a compensatory mechanism for cell survival.
Uvarov AV, Mesaeli N
Biochim Biophys Acta. 2008
PubMed ID: 18405668
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Lectin-deficient calreticulin retains full functionality as a chaperone for class I histocompatibility molecules.
Ireland BS, Brockmeier U, Howe CM, Elliott T, Williams DB
Mol Biol Cell. 2008
PubMed ID: 18337472
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Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane.
Rardin MJ, Wiley SE, Murphy AN, Pagliarini DJ, Dixon JE
J Biol Chem. 2008
PubMed ID: 18385140
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Calreticulin in human pregnancy and pre-eclampsia.
Gu VY, Wong MH, Stevenson JL, Crawford KE, Brennecke SP, Gude NM
Mol Hum Reprod. 2008
PubMed ID: 18417548
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Getting in and out from calnexin/calreticulin cycles.
Caramelo JJ, Parodi AJ
J Biol Chem. 2008
PubMed ID: 18303019
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Kinase-dependent adhesion to fibronectin: regulation by calreticulin.
Papp S, Szabo E, Kim H, McCulloch CA, Opas M
Exp Cell Res. 2008
PubMed ID: 18255058
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Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system.
Takahata M, Bohgaki M, Tsukiyama T, Kondo T, Asaka M, Hatakeyama S
Mol Immunol. 2008
PubMed ID: 18022694
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Regulation of the calreticulin gene by GATA6 and Evi-1 transcription factors.
Qiu Y, Lynch J, Guo L, Yatsula B, Perkins AS, Michalak M
Biochemistry. 2008
PubMed ID: 18303859
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Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control region.
Noordermeer D, Branco MR, Splinter E, Klous P, van Ijcken W, Swagemakers S, Koutsourakis M, van der Spek P, Pombo A, de Laat W
PLoS Genet. 2008
PubMed ID: 18369441
-
Calreticulin requires an ancillary adjuvant for the induction of efficient cytotoxic T cell responses.
Bak SP, Amiel E, Walters JJ, Berwin B
Mol Immunol. 2008
PubMed ID: 17936359
-
The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases.
Pagh R, Duus K, Laursen I, Hansen PR, Mangor J, Thielens N, Arlaud GJ, Kongerslev L, Højrup P, Houen G
FEBS J. 2008
PubMed ID: 18177377
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Calreticulin expression in the clonal plasma cells of patients with systemic light-chain (AL-) amyloidosis is associated with response to high-dose melphalan.
Zhou P, Teruya-Feldstein J, Lu P, Fleisher M, Olshen A, Comenzo RL
Blood. 2008
PubMed ID: 17982021
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Interaction of calreticulin with amyloid beta peptide 1-42.
Duus K, Hansen PR, Houen G
Protein Pept Lett. 2008
PubMed ID: 18221019
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Novel anti-oxidative role of calreticulin in protecting A549 human type II alveolar epithelial cells against hypoxic injury.
Jia L, Xu M, Zhen W, Shen X, Zhu Y, Wang W, Wang X
Am J Physiol Cell Physiol. 2008
PubMed ID: 17959730
-
Proteomic analysis of immature murine melanocytes at different stages of maturation: a crucial role for calreticulin.
Kawase A, Kushimoto T, Kawa Y, Ohsumi K, Nishikawa H, Kawakami T, Mizoguchi M, Soma Y
J Dermatol Sci. 2008
PubMed ID: 17826037
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The rheumatoid arthritis shared epitope triggers innate immune signaling via cell surface calreticulin.
Ling S, Pi X, Holoshitz J
J Immunol. 2007
PubMed ID: 17947714
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Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library.
Mohrlüder J, Stangler T, Hoffmann Y, Wiesehan K, Mataruga A, Willbold D
FEBS J. 2007
PubMed ID: 17916189
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Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse.
Zhang X, Szabo E, Michalak M, Opas M
Int J Dev Neurosci. 2007
PubMed ID: 17913437
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Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Obeid M, Panaretakis T, Joza N, Tufi R, Tesniere A, van Endert P, Zitvogel L, Kroemer G
Cell Death Differ. 2007
PubMed ID: 17657249
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Differential calreticulin expression affects focal contacts via the calmodulin/CaMK II pathway.
Szabo E, Papp S, Opas M
J Cell Physiol. 2007
PubMed ID: 17516550
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Genetic screening of calcium regulation genes in familial hypertrophic cardiomyopathy.
Chiu C, Tebo M, Ingles J, Yeates L, Arthur JW, Lind JM, Semsarian C
J Mol Cell Cardiol. 2007
PubMed ID: 17655857
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Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia.
Song L, Alcalai R, Arad M, Wolf CM, Toka O, Conner DA, Berul CI, Eldar M, Seidman CE, Seidman JG
J Clin Invest. 2007
PubMed ID: 17607358
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Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.
Hattori K, Nakamura K, Hisatomi Y, Matsumoto S, Suzuki M, Harvey RP, Kurihara H, Hattori S, Yamamoto T, Michalak M, Endo F
Mol Genet Metab. 2007
PubMed ID: 17482496
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Differential expression and activity of matrix metalloproteinase-2 and -9 in the calreticulin deficient cells.
Wu M, Massaeli H, Durston M, Mesaeli N
Matrix Biol. 2007
PubMed ID: 17412577
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Dissecting focal adhesions in cells differentially expressing calreticulin: a microscopy study.
Papp S, Fadel MP, Opas M
Biol Cell. 2007
PubMed ID: 17373910
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Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum.
Ramos RR, Swanson AJ, Bass J
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17563366
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Peptide binding specificity of the chaperone calreticulin.
Sandhu N, Duus K, Jørgensen CS, Hansen PR, Bruun SW, Pedersen LØ, Højrup P, Houen G
Biochim Biophys Acta. 2007
PubMed ID: 17499031
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Altered Calreticulin expression in human colon cancer: maintenance of Calreticulin expression is associated with mucinous differentiation.
Toquet C, Jarry A, Bou-Hanna C, Bach K, Denis MG, Mosnier JF, Laboisse CL
Oncol Rep. 2007
PubMed ID: 17390051
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Purification and identification of G protein-coupled receptor protein complexes under native conditions.
Daulat AM, Maurice P, Froment C, Guillaume JL, Broussard C, Monsarrat B, Delagrange P, Jockers R
Mol Cell Proteomics. 2007
PubMed ID: 17215244
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Post-translational arginylation of calreticulin: a new isospecies of calreticulin component of stress granules.
Decca MB, Carpio MA, Bosc C, Galiano MR, Job D, Andrieux A, Hallak ME
J Biol Chem. 2007
PubMed ID: 17197444
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Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies.
Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kirber MT, Summer RS, Kihara S, Walsh K
J Clin Invest. 2007
PubMed ID: 17256056
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Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
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Calreticulin exposure dictates the immunogenicity of cancer cell death.
Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, Perfettini JL, Castedo M, Mignot G, Panaretakis T, Casares N, Métivier D, Larochette N, van Endert P, Ciccosanti F, Piacentini M, Zitvogel L, Kroemer G
Nat Med. 2007
PubMed ID: 17187072
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Partial reversal of transformed fusiform phenotype by overexpression of calreticulin.
Opas M, Fadel MP
Cell Mol Biol Lett. 2007
PubMed ID: 17149557
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Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.
Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, Sadighi Akha AA, Raden D, Kaufman RJ
PLoS Biol. 2006
PubMed ID: 17090218
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Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver.
Timchenko LT, Salisbury E, Wang GL, Nguyen H, Albrecht JH, Hershey JW, Timchenko NA
J Biol Chem. 2006
PubMed ID: 16931514
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Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.
Park B, Lee S, Kim E, Cho K, Riddell SR, Cho S, Ahn K
Cell. 2006
PubMed ID: 17055437
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Reduced expression of Ca2+-regulating proteins in the upper gastrointestinal tract of patients with achalasia.
Fischer H, Fischer J, Boknik P, Gergs U, Schmitz W, Domschke W, Konturek JW, Neumann J
World J Gastroenterol. 2006
PubMed ID: 17009399
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Dendritic cell surface calreticulin is a receptor for NY-ESO-1: direct interactions between tumor-associated antigen and the innate immune system.
Zeng G, Aldridge ME, Tian X, Seiler D, Zhang X, Jin Y, Rao J, Li W, Chen D, Langford MP, Duggan C, Belldegrun AS, Dubinett SM
J Immunol. 2006
PubMed ID: 16951317
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Calreticulin, a molecular chaperone in the endoplasmic reticulum, modulates radiosensitivity of human glioblastoma U251MG cells.
Okunaga T, Urata Y, Goto S, Matsuo T, Mizota S, Tsutsumi K, Nagata I, Kondo T, Ihara Y
Cancer Res. 2006
PubMed ID: 16951181
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GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development.
Luo S, Mao C, Lee B, Lee AS
Mol Cell Biol. 2006
PubMed ID: 16847323
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The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest.
Du YC, Gu S, Zhou J, Wang T, Cai H, Macinnes MA, Bradbury EM, Chen X
Mol Cell Proteomics. 2006
PubMed ID: 16522924
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Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator.
Harada K, Okiyoneda T, Hashimoto Y, Ueno K, Nakamura K, Yamahira K, Sugahara T, Shuto T, Wada I, Suico MA, Kai H
J Biol Chem. 2006
PubMed ID: 16527813
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The calcium- and zinc-responsive regions of calreticulin reside strictly in the N-/C-domain.
Tan Y, Chen M, Li Z, Mabuchi K, Bouvier M
Biochim Biophys Acta. 2006
PubMed ID: 16542777
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Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR.
Vegh Z, Kew RR, Gruber BL, Ghebrehiwet B
Mol Immunol. 2006
PubMed ID: 16140380
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Regulation of peripheral T cell activation by calreticulin.
Porcellini S, Traggiai E, Schenk U, Ferrera D, Matteoli M, Lanzavecchia A, Michalak M, Grassi F
J Exp Med. 2006
PubMed ID: 16492806
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Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells.
Shao L, Sun X, Xu L, Young LT, Wang JF
Life Sci. 2006
PubMed ID: 16236328
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Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum.
Williams DB
J Cell Sci. 2006
PubMed ID: 16467570
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Identification by mutational analysis of amino acid residues essential in the chaperone function of calreticulin.
Martin V, Groenendyk J, Steiner SS, Guo L, Dabrowska M, Parker JM, Müller-Esterl W, Opas M, Michalak M
J Biol Chem. 2006
PubMed ID: 16291754
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Ultrastructural analysis of development of myocardium in calreticulin-deficient mice.
Lozyk MD, Papp S, Zhang X, Nakamura K, Michalak M, Opas M
BMC Dev Biol. 2006
PubMed ID: 17112388
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Calreticulin as a new histone binding protein in mitotic chromosomes.
Kobayashi S, Uchiyama S, Sone T, Noda M, Lin L, Mizuno H, Matsunaga S, Fukui K
Cytogenet Genome Res. 2006
PubMed ID: 16974078
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Role of calreticulin in the sensitivity of myocardiac H9c2 cells to oxidative stress caused by hydrogen peroxide.
Ihara Y, Urata Y, Goto S, Kondo T
Am J Physiol Cell Physiol. 2006
PubMed ID: 16135540
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Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.
Guo D, Han J, Adam BL, Colburn NH, Wang MH, Dong Z, Eizirik DL, She JX, Wang CY
Biochem Biophys Res Commun. 2005
PubMed ID: 16236267
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Estrogen regulation of the rat anterior pituitary gland proteome.
Blake CA, Brown LM, Duncan MW, Hunsucker SW, Helmke SM
Exp Biol Med (Maywood). 2005
PubMed ID: 16339744
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Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.
Machka C, Kersten M, Zobawa M, Harder A, Horsch M, Halder T, Lottspeich F, Hrabé de Angelis M, Beckers J
Gene Expr Patterns. 2005
PubMed ID: 15979417
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Mixed-disulfide folding intermediates between thyroglobulin and endoplasmic reticulum resident oxidoreductases ERp57 and protein disulfide isomerase.
Di Jeso B, Park YN, Ulianich L, Treglia AS, Urbanas ML, High S, Arvan P
Mol Cell Biol. 2005
PubMed ID: 16260597
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Conformational stability of calreticulin.
Jørgensen CS, Trandum C, Larsen N, Ryder LR, Gajhede M, Skov LK, Højrup P, Barkholt V, Houen G
Protein Pept Lett. 2005
PubMed ID: 16522185
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Retrotranslocation of the chaperone calreticulin from the endoplasmic reticulum lumen to the cytosol.
Afshar N, Black BE, Paschal BM
Mol Cell Biol. 2005
PubMed ID: 16199864
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Regulation of protein compartmentalization expands the diversity of protein function.
Shaffer KL, Sharma A, Snapp EL, Hegde RS
Dev Cell. 2005
PubMed ID: 16198296
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Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis.
Bruneel A, Labas V, Mailloux A, Sharma S, Royer N, Vinh J, Pernet P, Vaubourdolle M, Baudin B
Proteomics. 2005
PubMed ID: 16130169
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Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
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CBFB-SMMHC is correlated with increased calreticulin expression and suppresses the granulocytic differentiation factor CEBPA in AML with inv(16).
Helbling D, Mueller BU, Timchenko NA, Schardt J, Eyer M, Betts DR, Jotterand M, Meyer-Monard S, Fey MF, Pabst T
Blood. 2005
PubMed ID: 15855281
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Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia.
Barrow KM, Ward CM, Rutter J, Ali S, Stern PL
Dev Dyn. 2005
PubMed ID: 15977177
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Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca(2+)-dependent signaling cascade.
Lynch J, Guo L, Gelebart P, Chilibeck K, Xu J, Molkentin JD, Agellon LB, Michalak M
J Cell Biol. 2005
PubMed ID: 15998798
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Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface.
Vance BA, Harley PH, Backlund PS, Ward Y, Phelps TL, Gress RE
Arch Biochem Biophys. 2005
PubMed ID: 15893733
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Overexpression of calreticulin sensitizes SERCA2a to oxidative stress.
Ihara Y, Kageyama K, Kondo T
Biochem Biophys Res Commun. 2005
PubMed ID: 15766574
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Soluble tyrosinase is an endoplasmic reticulum (ER)-associated degradation substrate retained in the ER by calreticulin and BiP/GRP78 and not calnexin.
Popescu CI, Paduraru C, Dwek RA, Petrescu SM
J Biol Chem. 2005
PubMed ID: 15677452
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Impaired cytolytic activity in calreticulin-deficient CTLs.
Sipione S, Ewen C, Shostak I, Michalak M, Bleackley RC
J Immunol. 2005
PubMed ID: 15749851
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Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum.
Gelebart P, Opas M, Michalak M
Int J Biochem Cell Biol. 2005
PubMed ID: 15474971
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Autocrine regulation of T cell motility by calreticulin-thrombospondin-1 interaction.
Li SS, Forslöw A, Sundqvist KG
J Immunol. 2005
PubMed ID: 15634883
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Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).
Lepourcelet M, Tou L, Cai L, Sawada J, Lazar AJ, Glickman JN, Williamson JA, Everett AD, Redston M, Fox EA, Nakatani Y, Shivdasani RA
Development. 2005
PubMed ID: 15604097
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Calreticulin promotes folding of functional human leukocyte antigen class I molecules in vitro.
Culina S, Lauvau G, Gubler B, van Endert PM
J Biol Chem. 2004
PubMed ID: 15494401
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SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.
Berwin B, Delneste Y, Lovingood RV, Post SR, Pizzo SV
J Biol Chem. 2004
PubMed ID: 15371419
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Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
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Diagnostic potential in bladder cancer of a panel of tumor markers (calreticulin, gamma -synuclein, and catechol-o-methyltransferase) identified by proteomic analysis.
Iwaki H, Kageyama S, Isono T, Wakabayashi Y, Okada Y, Yoshimura K, Terai A, Arai Y, Iwamura H, Kawakita M, Yoshiki T
Cancer Sci. 2004
PubMed ID: 15596044
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Signaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain.
Nakamura M, Sato K, Fukaya M, Araishi K, Aiba A, Kano M, Watanabe M
Eur J Neurosci. 2004
PubMed ID: 15579147
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Gentamicin binds to the lectin site of calreticulin and inhibits its chaperone activity.
Horibe T, Matsui H, Tanaka M, Nagai H, Yamaguchi Y, Kato K, Kikuchi M
Biochem Biophys Res Commun. 2004
PubMed ID: 15351734
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
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A polypeptide binding conformation of calreticulin is induced by heat shock, calcium depletion, or by deletion of the C-terminal acidic region.
Rizvi SM, Mancino L, Thammavongsa V, Cantley RL, Raghavan M
Mol Cell. 2004
PubMed ID: 15383281
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An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer.
Hong SH, Misek DE, Wang H, Puravs E, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM
Cancer Res. 2004
PubMed ID: 15289361
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NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.
Zhu H, Larade K, Jackson TA, Xie J, Ladoux A, Acker H, Berchner-Pfannschmidt U, Fandrey J, Cross AR, Lukat-Rodgers GS, Rodgers KR, Bunn HF
J Biol Chem. 2004
PubMed ID: 15131110
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ER-60 domains responsible for interaction with calnexin and calreticulin.
Urade R, Okudo H, Kato H, Moriyama T, Arakaki Y
Biochemistry. 2004
PubMed ID: 15236594
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Calreticulin on the mouse egg surface mediates transmembrane signaling linked to cell cycle resumption.
Tutuncu L, Stein P, Ord TS, Jorgez CJ, Williams CJ
Dev Biol. 2004
PubMed ID: 15136153
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Multigenic control of hepatic iron loading in a murine model of hemochromatosis.
Bensaid M, Fruchon S, Mazères C, Bahram S, Roth MP, Coppin H
Gastroenterology. 2004
PubMed ID: 15131800
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The DNA sequence and biology of human chromosome 19.
Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM
Nature. 2004
PubMed ID: 15057824
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Impaired p53 expression, function, and nuclear localization in calreticulin-deficient cells.
Mesaeli N, Phillipson C
Mol Biol Cell. 2004
PubMed ID: 14767071
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The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts.
Orlando RA
Exp Cell Res. 2004
PubMed ID: 14980518
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Identification of chromosomes associated with dental caries susceptibility using quantitative trait locus analysis in mice.
Nariyama M, Shimizu K, Uematsu T, Maeda T
Caries Res. 2004
PubMed ID: 14767162
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Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.
Reilly D, Larkin D, Devocelle M, Fitzgerald DJ, Moran N
Platelets. 2004
PubMed ID: 14985176
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Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.
Iakova P, Wang GL, Timchenko L, Michalak M, Pereira-Smith OM, Smith JR, Timchenko NA
EMBO J. 2004
PubMed ID: 14726956
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Differential downregulation of endoplasmic reticulum-residing chaperones calnexin and calreticulin in human metastatic melanoma.
Dissemond J, Busch M, Kothen T, Mörs J, Weimann TK, Lindeke A, Goos M, Wagner SN
Cancer Lett. 2004
PubMed ID: 14732231
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Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control.
Molinari M, Eriksson KK, Calanca V, Galli C, Cresswell P, Michalak M, Helenius A
Mol Cell. 2004
PubMed ID: 14731400
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Identification of an N-domain histidine essential for chaperone function in calreticulin.
Guo L, Groenendyk J, Papp S, Dabrowska M, Knoblach B, Kay C, Parker JM, Opas M, Michalak M
J Biol Chem. 2003
PubMed ID: 14522955
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Epitopes of calreticulin recognised by IgA autoantibodies from patients with hepatic and coeliac disease.
Sánchez D, Tucková L, Mothes T, Kreisel W, Benes Z, Tlaskalová-Hogenová H
J Autoimmun. 2003
PubMed ID: 14624761
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
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By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation.
Gardai SJ, Xiao YQ, Dickinson M, Nick JA, Voelker DR, Greene KE, Henson PM
Cell. 2003
PubMed ID: 14531999
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Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival.
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA
Mol Cell Biol. 2003
PubMed ID: 14517290
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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
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Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21).
Zhang L, Wu G, Tate CG, Lookene A, Olivecrona G
J Biol Chem. 2003
PubMed ID: 12740382
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Low density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassembly.
Orr AW, Pedraza CE, Pallero MA, Elzie CA, Goicoechea S, Strickland DK, Murphy-Ullrich JE
J Cell Biol. 2003
PubMed ID: 12821648
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Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule.
Ghiran I, Klickstein LB, Nicholson-Weller A
J Biol Chem. 2003
PubMed ID: 12646570
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Compromised calnexin function in calreticulin-deficient cells.
Knee R, Ahsan I, Mesaeli N, Kaufman RJ, Michalak M
Biochem Biophys Res Commun. 2003
PubMed ID: 12727205
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Identification of calreticulin as a nuclear matrix protein associated with human colon cancer.
Brünagel G, Shah U, Schoen RE, Getzenberg RH
J Cell Biochem. 2003
PubMed ID: 12704787
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Calreticulin--an endoplasmic reticulum protein with calcium-binding activity is also found in the extracellular matrix.
Somogyi E, Petersson U, Hultenby K, Wendel M
Matrix Biol. 2003
PubMed ID: 12782144
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Calreticulin-melatonin. An unexpected relationship.
Macías M, Escames G, Leon J, Coto A, Sbihi Y, Osuna A, Acuña-Castroviejo D
Eur J Biochem. 2003
PubMed ID: 12603316
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Cellular proteins from human monocytes bind to dengue 4 virus minus-strand 3' untranslated region RNA.
Yocupicio-Monroy RM, Medina F, Reyes-del Valle J, del Angel RM
J Virol. 2003
PubMed ID: 12584332
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Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B.
Zhang J, Herscovitz H
J Biol Chem. 2003
PubMed ID: 12397072
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Calreticulin inhibits the MEK1,2-ERK1,2 pathway in alpha 1-adrenergic receptor/Gh-stimulated hypertrophy of neonatal rat cardiomyocytes.
Lee KH, Lee N, Lim S, Jung H, Ko YG, Park HY, Jang Y, Lee H, Hwang KC
J Steroid Biochem Mol Biol. 2003
PubMed ID: 12648529
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Maturation-dependent expression of C1q binding proteins on the cell surface of human monocyte-derived dendritic cells.
Vegh Z, Goyarts EC, Rozengarten K, Mazumder A, Ghebrehiwet B
Int Immunopharmacol. 2003
PubMed ID: 12538033
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BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
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Cardiac-specific expression of calcineurin reverses embryonic lethality in calreticulin-deficient mouse.
Guo L, Nakamura K, Lynch J, Opas M, Olson EN, Agellon LB, Michalak M
J Biol Chem. 2002
PubMed ID: 12377773
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
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Calreticulin differentially modulates calcium uptake and release in the endoplasmic reticulum and mitochondria.
Arnaudeau S, Frieden M, Nakamura K, Castelbou C, Michalak M, Demaurex N
J Biol Chem. 2002
PubMed ID: 12324449
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Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.
Radcliffe CM, Diedrich G, Harvey DJ, Dwek RA, Cresswell P, Rudd PM
J Biol Chem. 2002
PubMed ID: 12235131
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Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain.
Kang SJ, Cresswell P
J Biol Chem. 2002
PubMed ID: 12239218
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Differential protein expression at the stage of neural tube closure in the mouse embryo.
Greene ND, Leung KY, Wait R, Begum S, Dunn MJ, Copp AJ
J Biol Chem. 2002
PubMed ID: 12200422
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The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin.
Goicoechea S, Pallero MA, Eggleton P, Michalak M, Murphy-Ullrich JE
J Biol Chem. 2002
PubMed ID: 12147682
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Association of the thyrotropin receptor with calnexin, calreticulin and BiP. Efects on the maturation of the receptor.
Siffroi-Fernandez S, Giraud A, Lanet J, Franc JL
Eur J Biochem. 2002
PubMed ID: 12383251
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Physical and functional interaction between cell-surface calreticulin and the collagen receptors integrin alpha2beta1 and glycoprotein VI in human platelets.
Elton CM, Smethurst PA, Eggleton P, Farndale RW
Thromb Haemost. 2002
PubMed ID: 12362238
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Calreticulin interacts with C/EBPalpha and C/EBPbeta mRNAs and represses translation of C/EBP proteins.
Timchenko LT, Iakova P, Welm AL, Cai ZJ, Timchenko NA
Mol Cell Biol. 2002
PubMed ID: 12242300
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NMR structures of 36 and 73-residue fragments of the calreticulin P-domain.
Ellgaard L, Bettendorff P, Braun D, Herrmann T, Fiorito F, Jelesarov I, Güntert P, Helenius A, Wüthrich K
J Mol Biol. 2002
PubMed ID: 12270713
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Identification of a novel calreticulin isoform (Crt2) in human and mouse.
Persson S, Rosenquist M, Sommarin M
Gene. 2002
PubMed ID: 12384296
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Myelin proteolipid protein forms a complex with integrins and may participate in integrin receptor signaling in oligodendrocytes.
Gudz TI, Schneider TE, Haas TA, Macklin WB
J Neurosci. 2002
PubMed ID: 12196561
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Ca2+-dependent nuclear export mediated by calreticulin.
Holaska JM, Black BE, Rastinejad F, Paschal BM
Mol Cell Biol. 2002
PubMed ID: 12167720
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Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum.
Clark RA, Li SL, Pearson DW, Leidal KG, Clark JR, Denning GM, Reddick R, Krause KH, Valente AJ
J Biol Chem. 2002
PubMed ID: 12065601
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Localization of the lectin, ERp57 binding, and polypeptide binding sites of calnexin and calreticulin.
Leach MR, Cohen-Doyle MF, Thomas DY, Williams DB
J Biol Chem. 2002
PubMed ID: 12052826
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Calreticulin reveals a critical Ca(2+) checkpoint in cardiac myofibrillogenesis.
Li J, Pucéat M, Perez-Terzic C, Mery A, Nakamura K, Michalak M, Krause KH, Jaconi ME
J Cell Biol. 2002
PubMed ID: 12105184
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Overexpression of calreticulin modulates protein kinase B/Akt signaling to promote apoptosis during cardiac differentiation of cardiomyoblast H9c2 cells.
Kageyama K, Ihara Y, Goto S, Urata Y, Toda G, Yano K, Kondo T
J Biol Chem. 2002
PubMed ID: 11907032
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Cellular location of proteins related to iron absorption and transport.
Simovich MJ, Conrad ME, Umbreit JN, Moore EG, Hainsworth LN, Smith HK
Am J Hematol. 2002
PubMed ID: 11891802
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The ferrireductase paraferritin contains divalent metal transporter as well as mobilferrin.
Umbreit JN, Conrad ME, Hainsworth LN, Simovich M
Am J Physiol Gastrointest Liver Physiol. 2002
PubMed ID: 11842004
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Calcitropic gene expression suggests a role for the intraplacental yolk sac in maternal-fetal calcium exchange.
Kovacs CS, Chafe LL, Woodland ML, McDonald KR, Fudge NJ, Wookey PJ
Am J Physiol Endocrinol Metab. 2002
PubMed ID: 11832378
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TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain.
Frickel EM, Riek R, Jelesarov I, Helenius A, Wuthrich K, Ellgaard L
Proc Natl Acad Sci U S A. 2002
PubMed ID: 11842220
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Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin.
Gao B, Adhikari R, Howarth M, Nakamura K, Gold MC, Hill AB, Knee R, Michalak M, Elliott T
Immunity. 2002
PubMed ID: 11825569
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Calreticulin is directly involved in anti-alpha3 integrin antibody-mediated secretion and activation of matrix metalloprotease-2.
Ito H, Seyama Y, Kubota S
Biochem Biophys Res Commun. 2001
PubMed ID: 11327697
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[Suppression of stress proteins, GRP78, GRP94, calreticulin and calnexin in liver endoplasmic reticulum of rat treated with a highly toxic coplanar PCB]
Yoshioka Y, Ishii Y, Ishida T, Yamada H, Oguri K, Motojima K
Fukuoka Igaku Zasshi. 2001
PubMed ID: 11452518
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Calreticulin functions as a molecular chaperone for the beta-amyloid precursor protein.
Johnson RJ, Xiao G, Shanmugaratnam J, Fine RE
Neurobiol Aging. 2001
PubMed ID: 11378243
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Complete heart block and sudden death in mice overexpressing calreticulin.
Nakamura K, Robertson M, Liu G, Dickie P, Nakamura K, Guo JQ, Duff HJ, Opas M, Kavanagh K, Michalak M
J Clin Invest. 2001
PubMed ID: 11375414
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Human placental calreticulin characterization of domain structure and post-translational modifications.
Højrup P, Roepstorff P, Houen G
Eur J Biochem. 2001
PubMed ID: 11322874
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NMR structure of the calreticulin P-domain.
Ellgaard L, Riek R, Herrmann T, Güntert P, Braun D, Helenius A, Wüthrich K
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11248044
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Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
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Calreticulin Is a receptor for nuclear export.
Holaska JM, Black BE, Love DC, Hanover JA, Leszyk J, Paschal BM
J Cell Biol. 2001
PubMed ID: 11149926
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The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
Bolt G
Arch Virol. 2001
PubMed ID: 11765911
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RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
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Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
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Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus.
Chen B, Wang JF, Young LT
Biol Psychiatry. 2000
PubMed ID: 11032977
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Calreticulin comes of age.
Llewellyn DH, Johnson S, Eggleton P
Trends Cell Biol. 2000
PubMed ID: 11032461
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The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo.
Pelletier MF, Marcil A, Sevigny G, Jakob CA, Tessier DC, Chevet E, Menard R, Bergeron JJ, Thomas DY
Glycobiology. 2000
PubMed ID: 10929008
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A novel von Willebrand disease-causing mutation (Arg273Trp) in the von Willebrand factor propeptide that results in defective multimerization and secretion.
Allen S, Abuzenadah AM, Hinks J, Blagg JL, Gursel T, Ingerslev J, Goodeve AC, Peake IR, Daly ME
Blood. 2000
PubMed ID: 10887119
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Calreticulin binding and other biological activities of survival peptide Y-P30 including effects of systemic treatment of rats.
Cunningham TJ, Jing H, Wang Y, Hodge L
Exp Neurol. 2000
PubMed ID: 10833321
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Mesenchymal-epithelial transition in the developing metanephric kidney: gene expression study by differential display.
Plisov SY, Ivanov SV, Yoshino K, Dove LF, Plisova TM, Higinbotham KG, Karavanova I, Lerman M, Perantoni AO
Genesis. 2000
PubMed ID: 10862152
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Heart, brain, and body wall defects in mice lacking calreticulin.
Rauch F, Prud'homme J, Arabian A, Dedhar S, St-Arnaud R
Exp Cell Res. 2000
PubMed ID: 10739657
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Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins.
Saito Y, Ihara Y, Leach MR, Cohen-Doyle MF, Williams DB
EMBO J. 1999
PubMed ID: 10581245
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Calreticulin: one protein, one gene, many functions.
Michalak M, Corbett EF, Mesaeli N, Nakamura K, Opas M
Biochem J. 1999
PubMed ID: 10567207
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Regulation of fibrillin carboxy-terminal furin processing by N-glycosylation, and association of amino- and carboxy-terminal sequences.
Ashworth JL, Kelly V, Rock MJ, Shuttleworth CA, Kielty CM
J Cell Sci. 1999
PubMed ID: 10547375
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Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules.
Knittler MR, Alberts P, Deverson EV, Howard JC
Curr Biol. 1999
PubMed ID: 10508608
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ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.
Oliver JD, Roderick HL, Llewellyn DH, High S
Mol Biol Cell. 1999
PubMed ID: 10436013
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Molecular chaperones stimulate the functional expression of the cocaine-sensitive serotonin transporter.
Tate CG, Whiteley E, Betenbaugh MJ
J Biol Chem. 1999
PubMed ID: 10364189
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Calreticulin is expressed on the cell surface of activated human peripheral blood T lymphocytes in association with major histocompatibility complex class I molecules.
Arosa FA, de Jesus O, Porto G, Carmo AM, de Sousa M
J Biol Chem. 1999
PubMed ID: 10358038
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Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.
Tatu U, Helenius A
Biosci Rep. 1999
PubMed ID: 10513896
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Calreticulin is essential for cardiac development.
Mesaeli N, Nakamura K, Zvaritch E, Dickie P, Dziak E, Krause KH, Opas M, MacLennan DH, Michalak M
J Cell Biol. 1999
PubMed ID: 10085286
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Calreticulin enhances the transcriptional activity of thyroid transcription factor-1 by binding to its homeodomain.
Perrone L, Tell G, Di Lauro R
J Biol Chem. 1999
PubMed ID: 9988700
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Genes regulating MHC class I processing of antigen.
van Endert PM
Curr Opin Immunol. 1999
PubMed ID: 10047538
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
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Calreticulin: an intracellular Ca++-binding protein abundantly expressed and regulated by androgen in prostatic epithelial cells.
Zhu N, Pewitt EB, Cai X, Cohn EB, Lang S, Chen R, Wang Z
Endocrinology. 1998
PubMed ID: 9751517
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Interaction between a Ca2+-binding protein calreticulin and perforin, a component of the cytotoxic T-cell granules.
Andrin C, Pinkoski MJ, Burns K, Atkinson EA, Krahenbuhl O, Hudig D, Fraser SA, Winkler U, Tschopp J, Opas M, Bleackley RC, Michalak M
Biochemistry. 1998
PubMed ID: 9671507
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Placental 57-kDa Ca(2+)-binding protein: regulation of expression and function in trophoblast calcium transport.
Hershberger ME, Tuan RS
Dev Biol. 1998
PubMed ID: 9676194
-
Calreticulin.
Coppolino MG, Dedhar S
Int J Biochem Cell Biol. 1998
PubMed ID: 9693955
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ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.
Lindquist JA, Jensen ON, Mann M, Hämmerling GJ
EMBO J. 1998
PubMed ID: 9545232
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Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin.
Pipe SW, Morris JA, Shah J, Kaufman RJ
J Biol Chem. 1998
PubMed ID: 9525969
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Calnexin and calreticulin bind to enzymically active tissue-type plasminogen activator during biosynthesis and are not required for folding to the native conformation.
Allen S, Bulleid NJ
Biochem J. 1997
PubMed ID: 9359841
-
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S
Gene. 1997
PubMed ID: 9373149
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Promotion of transferrin folding by cyclic interactions with calnexin and calreticulin.
Wada I, Kai M, Imai S, Sakane F, Kanoh H
EMBO J. 1997
PubMed ID: 9312001
-
Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion.
Coppolino MG, Woodside MJ, Demaurex N, Grinstein S, St-Arnaud R, Dedhar S
Nature. 1997
PubMed ID: 9126744
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Nuclear localisation of calreticulin in vivo is enhanced by its interaction with glucocorticoid receptors.
Roderick HL, Campbell AK, Llewellyn DH
FEBS Lett. 1997
PubMed ID: 9089287
-
A two-dimensional gel database of human colon carcinoma proteins.
Ji H, Reid GE, Moritz RL, Eddes JS, Burgess AW, Simpson RJ
Electrophoresis. 1997
PubMed ID: 9150948
-
Prominence of beta 2-microglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing.
Solheim JC, Harris MR, Kindle CS, Hansen TH
J Immunol. 1997
PubMed ID: 9036970
-
Calreticulin.
Krause KH, Michalak M
Cell. 1997
PubMed ID: 9038335
-
Mapping of the gene for calreticulin (Calr) to mouse chromosome 8.
Rooke K, Briquet-Laugier V, Xia YR, Lusis AJ, Doolittle MH
Mamm Genome. 1997
PubMed ID: 9337407
-
Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit.
Trombetta ES, Simons JF, Helenius A
J Biol Chem. 1996
PubMed ID: 8910335
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Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.
Sadasivan B, Lehner PJ, Ortmann B, Spies T, Cresswell P
Immunity. 1996
PubMed ID: 8769474
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Calreticulin expression in spinal motoneurons of the rat.
Copray JC, Liem RS, Kernell D
J Chem Neuroanat. 1996
PubMed ID: 8841889
-
Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP.
Lewis JW, Neisig A, Neefjes J, Elliott T
Curr Biol. 1996
PubMed ID: 8805302
-
The glut 1 glucose transporter interacts with calnexin and calreticulin.
Oliver JD, Hresko RC, Mueckler M, High S
J Biol Chem. 1996
PubMed ID: 8662691
-
Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen.
Cheng ST, Nguyen TQ, Yang YS, Capra JD, Sontheimer RD
J Immunol. 1996
PubMed ID: 8666824
-
Alterations of expression and distribution of the Ca(2+)-storing proteins in endo/sarcoplasmic reticulum during differentiation of rat cardiomyocytes.
Imanaka-Yoshida K, Amitani A, Ioshii SO, Koyabu S, Yamakado T, Yoshida T
J Mol Cell Cardiol. 1996
PubMed ID: 9011638
-
Complete congenital heart block is associated with increased autoantibody titers against calreticulin.
Orth T, Dorner T, Meyer Zum Buschenfelde KH, Mayet WJ
Eur J Clin Invest. 1996
PubMed ID: 8904349
-
Regulation of calcium binding proteins calreticulin and calsequestrin during differentiation in the myogenic cell line L6.
Tharin S, Hamel PA, Conway EM, Michalak M, Opas M
J Cell Physiol. 1996
PubMed ID: 8600158
-
Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope glycoprotein, suggesting a chaperone function similar to that of calnexin.
Otteken A, Moss B
J Biol Chem. 1996
PubMed ID: 8550632
-
Interaction of calreticulin with protein disulfide isomerase.
Baksh S, Burns K, Andrin C, Michalak M
J Biol Chem. 1995
PubMed ID: 8537405
-
The mitogenic effects of the B beta chain of fibrinogen are mediated through cell surface calreticulin.
Gray AJ, Park PW, Broekelmann TJ, Laurent GJ, Reeves JT, Stenmark KR, Mecham RP
J Biol Chem. 1995
PubMed ID: 7592883
-
Inducible interaction of integrin alpha 2 beta 1 with calreticulin. Dependence on the activation state of the integrin.
Coppolino M, Leung-Hagesteijn C, Dedhar S, Wilkins J
J Biol Chem. 1995
PubMed ID: 7559457
-
Heat shock-sensitive expression of calreticulin. In vitro and in vivo up-regulation.
Conway EM, Liu L, Nowakowski B, Steiner-Mosonyi M, Ribeiro SP, Michalak M
J Biol Chem. 1995
PubMed ID: 7622522
-
Calreticulin functions as a molecular chaperone in the biosynthesis of myeloperoxidase.
Nauseef WM, McCormick SJ, Clark RA
J Biol Chem. 1995
PubMed ID: 7876246
-
Human placental calreticulin: purification, characterization and association with other proteins.
Houen G, Koch C
Acta Chem Scand. 1994
PubMed ID: 7841019
-
Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum.
Sönnichsen B, Füllekrug J, Nguyen Van P, Diekmann W, Robinson DG, Mieskes G
J Cell Sci. 1994
PubMed ID: 7876339
-
Calreticulin is released from activated neutrophils and binds to C1q and mannan-binding protein.
Eggleton P, Lieu TS, Zappi EG, Sastry K, Coburn J, Zaner KS, Sontheimer RD, Capra JD, Ghebrehiwet B, Tauber AI
Clin Immunol Immunopathol. 1994
PubMed ID: 8062452
-
Viral induction of the human autoantigen calreticulin.
Zhu J, Newkirk MM
Clin Invest Med. 1994
PubMed ID: 7923996
-
Separation and sequencing of familiar and novel murine proteins using preparative two-dimensional gel electrophoresis.
Merrick BA, Patterson RM, Witcher LL, He C, Selkirk JK
Electrophoresis. 1994
PubMed ID: 7523108
-
Systemic lupus erythematosus is associated with increased auto-antibody titers against calreticulin and grp94, but calreticulin is not the Ro/SS-A antigen.
Boehm J, Orth T, Van Nguyen P, Söling HD
Eur J Clin Invest. 1994
PubMed ID: 8050453
-
Cell attachment to extracellular matrix substrates is inhibited upon downregulation of expression of calreticulin, an intracellular integrin alpha-subunit-binding protein.
Leung-Hagesteijn CY, Milankov K, Michalak M, Wilkins J, Dedhar S
J Cell Sci. 1994
PubMed ID: 8006073
-
Inhibition of nuclear hormone receptor activity by calreticulin.
Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ
Nature. 1994
PubMed ID: 8107809
-
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor.
Burns K, Duggan B, Atkinson EA, Famulski KS, Nemer M, Bleackley RC, Michalak M
Nature. 1994
PubMed ID: 8107808
-
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
Maruyama K, Sugano S
Gene. 1994
PubMed ID: 8125298
-
Identification of protein disulfide isomerase and calreticulin as autoimmune antigens in LEC strain of rats.
Yokoi T, Nagayama S, Kajiwara R, Kawaguchi Y, Horiuchi R, Kamataki T
Biochim Biophys Acta. 1993
PubMed ID: 8251535
-
Rat duodenal iron-binding protein mobilferrin is a homologue of calreticulin.
Conrad ME, Umbreit JN, Moore EG
Gastroenterology. 1993
PubMed ID: 8500729
-
An endoplasmic reticulum protein, calreticulin, is transported into the acrosome of rat sperm.
Nakamura M, Moriya M, Baba T, Michikawa Y, Yamanobe T, Arai K, Okinaga S, Kobayashi T
Exp Cell Res. 1993
PubMed ID: 8453984
-
The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes.
Dupuis M, Schaerer E, Krause KH, Tschopp J
J Exp Med. 1993
PubMed ID: 8418194
-
Human liver protein map: a reference database established by microsequencing and gel comparison.
Hochstrasser DF, Frutiger S, Paquet N, Bairoch A, Ravier F, Pasquali C, Sanchez JC, Tissot JD, Bjellqvist B, Vargas R
Electrophoresis. 1992
PubMed ID: 1286669
-
Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
Rasmussen HH, van Damme J, Puype M, Gesser B, Celis JE, Vandekerckhove J
Electrophoresis. 1992
PubMed ID: 1286667
-
Determination of the sequence of an expressible cDNA clone encoding ERp60/calregulin by the use of a novel nested set method.
Mazzarella RA, Gold P, Cunningham M, Green M
Gene. 1992
PubMed ID: 1398135
-
Calreticulin.
Michalak M, Milner RE, Burns K, Opas M
Biochem J. 1992
PubMed ID: 1497605
-
Localization of gene expression of calreticulin in the brain of adult mouse.
Abe H, Watanabe M, Goto K, Sakagami H, Kondo H
Brain Res Mol Brain Res. 1992
PubMed ID: 1326696
-
Calreticulin is present in the acrosome of spermatids of rat testis.
Nakamura M, Michikawa Y, Baba T, Okinaga S, Arai K
Biochem Biophys Res Commun. 1992
PubMed ID: 1497655
-
The 5'-flanking region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters.
McCauliffe DP, Yang YS, Wilson J, Sontheimer RD, Capra JD
J Biol Chem. 1992
PubMed ID: 1733953
-
Characterization of the autoantigen calreticulin.
Rokeach LA, Haselby JA, Meilof JF, Smeenk RJ, Unnasch TR, Greene BM, Hoch SO
J Immunol. 1991
PubMed ID: 1919005
-
In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits.
Rojiani MV, Finlay BB, Gray V, Dedhar S
Biochemistry. 1991
PubMed ID: 1911778
-
Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells.
Opas M, Dziak E, Fliegel L, Michalak M
J Cell Physiol. 1991
PubMed ID: 1939344
-
Calreticulin is a candidate for a calsequestrin-like function in Ca2(+)-storage compartments (calciosomes) of liver and brain.
Treves S, De Mattei M, Landfredi M, Villa A, Green NM, MacLennan DH, Meldolesi J, Pozzan T
Biochem J. 1990
PubMed ID: 2241926
-
Sequence similarity of calreticulin with a Ca2(+)-binding protein that co-purifies with an Ins(1,4,5)P3-sensitive Ca2+ store in HL-60 cells.
Krause KH, Simmerman HK, Jones LR, Campbell KP
Biochem J. 1990
PubMed ID: 2400400
-
Structural homology between the rat calreticulin gene product and the Onchocerca volvulus antigen Ral-1.
Murthy KK, Banville D, Srikant CB, Carrier F, Holmes C, Bell A, Patel YC
Nucleic Acids Res. 1990
PubMed ID: 2395661
-
A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia "memory molecule".
McCauliffe DP, Zappi E, Lieu TS, Michalak M, Sontheimer RD, Capra JD
J Clin Invest. 1990
PubMed ID: 2365822
-
Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.
McCauliffe DP, Lux FA, Lieu TS, Sanz I, Hanke J, Newkirk MM, Bachinski LL, Itoh Y, Siciliano MJ, Reichlin M
J Clin Invest. 1990
PubMed ID: 2332496
-
Multiple zones in the sequence of calreticulin (CRP55, calregulin, HACBP), a major calcium binding ER/SR protein.
Smith MJ, Koch GL
EMBO J. 1989
PubMed ID: 2583110
-
Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptide.
Lieu TS, Newkirk MM, Capra JD, Sontheimer RD
J Clin Invest. 1988
PubMed ID: 3260607
-
Mouse placental 57-kDa calcium-binding protein: I. Cloning of cDNA and characterization of developmental expression.
Tuan RS, Kirwin JJ
Differentiation. 1988
PubMed ID: 2456241
-
Identification and characterization of a calcium-binding protein in the mouse chorioallantoic placenta.
Tuan RS, Cavanaugh ST
Biochem J. 1986
PubMed ID: 3513762
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