CALM2

Summary Top Help

Gene Description:

calmodulin 2 (phosphorylase kinase, delta); calmodulin 2

Synonyms:

PHKD, Calm2, CAMII, CALM3, Calm3, AL024017, CALM1, PHKD2, 1500001E21Rik, Calm1, CALM2

Orthologs:

Human CALM2 (protein-coding), Mouse Calm2 (protein-coding), Rat Calm2 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr2:47292896..47403740 (110.84 kb) View in Genome Browser

(Mouse) NCBIM37 - chr17:87832741..87846275 (13.53 kb) View in Genome Browser

(Rat) RGSC3.4 - chr15:64161641..64162751 (1.11 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for CALM2:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for CALM2:

The CALM2 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.

The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.

Interactor	Interactor	Sources	Classification	Pubmed IDs
CALM2	DLG1	HPRD	empirical	12189141
CALM2	EGFR	HPRD	empirical	12153558
CALM2	ESR1	HPRD	empirical	11981030
CALM2	ESR2	HPRD	empirical	11981030
CALM2	GRM5	HPRD	empirical	9242710 11953448
CALM2	GRM7	HPRD	empirical	11953448
CALM2	INSR	HPRD	empirical	12153558
CALM2	KCNQ2	HPRD	empirical	12032157
CALM2	KCNQ3	HPRD	empirical	12032157
CALM2	MARCKS	HPRD	empirical	12577052
CALM2	ASCL2	HPRD	empirical	10757985
CALM2	MYF5	HPRD	empirical	10757985
CALM2	MYF6	HPRD	empirical	10757985
CALM2	MYO6	HPRD	empirical	16169070
CALM2	MYOD1	HPRD	empirical	10757985
CALM2	MYOG	HPRD	empirical	10757985
CALM2	NEUROD1	HPRD	empirical	10757985
CALM2	PCNT	HPRD	empirical	12221128 10823944
CALM2	PPEF2	HPRD	empirical	12051765
CALM2	PPEF1	HPRD	empirical	12051765
CALM2	MRPL20	HPRD	empirical	16169070
CALM2	KCNQ5	HPRD	empirical	12032157
CALM2	RAB3B	HPRD	empirical	11741295
CALM2	TCF4	HPRD	empirical	10757985
CALM2	CALD1	HPRD	empirical	11736632
CALM2	KIAA1683	HPRD	empirical	16189514
CALM2	EDF1	HPRD	empirical	10816571
CALM2	IQCB1	HPRD	empirical	15723066

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 16

Biocarta: 20

Reactome: 37

NCI-Nature Pathway Interaction Database: 16

Gene Ontology: None available

Publications from PubMed Top Help

Type 1 Diabetes Publications: 1

Publications: 146

Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.
Jiang W, Wang S, Xiao M, Lin Y, Zhou L, Lei Q, Xiong Y, Guan KL, Zhao S
Mol Cell. 2011
PubMed ID: 21726808
Central nicotinic acetylcholine receptor involved in Ca(2+) -calmodulin-endothelial nitric oxide synthase pathway modulated hypotensive effects.
Cheng PW, Lu PJ, Chen SR, Ho WY, Cheng WH, Hong LZ, Yeh TC, Sun GC, Wang LL, Hsiao M, Tseng CJ
Br J Pharmacol. 2011
PubMed ID: 21091651
Genome-Wide Association Scan for Survival on Dialysis in African-Americans with Type 2 Diabetes.
Murea M, Lu L, Ma L, Hicks PJ, Divers J, McDonough CW, Langefeld CD, Bowden DW, Freedman BI
Am J Nephrol. 2011
PubMed ID: 21546767
Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5.
Chagot B, Chazin WJ
J Mol Biol. 2011
PubMed ID: 21167176
Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.
Kahle JJ, Gulbahce N, Shaw CA, Lim J, Hill DE, Barabási AL, Zoghbi HY
Hum Mol Genet. 2011
PubMed ID: 21078624
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients.
Wang P, Mao Y, Razo J, Zhou X, Wong ST, Patel S, Elliott E, Shea E, Wu AH, Gaber AO
Pharmacogenomics. 2010
PubMed ID: 21047202
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling.
Xu G, Paige JS, Jaffrey SR
Nat Biotechnol. 2010
PubMed ID: 20639865
Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex.
Wang Z, Wu T, Shi L, Zhang L, Zheng W, Qu JY, Niu R, Qi RZ
J Biol Chem. 2010
PubMed ID: 20466722
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
Biological Pathway-Based Genome-Wide Association Analysis Identified the Vasoactive Intestinal Peptide (VIP) Pathway Important for Obesity.
Liu YJ, Guo YF, Zhang LS, Pei YF, Yu N, Yu P, Papasian CJ, Deng HW
Obesity (Silver Spring). 2010
PubMed ID: 20379146
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Yang X, Zou P, Yao J, Yun D, Bao H, Du R, Long J, Chen X
J Proteome Res. 2010
PubMed ID: 20000738
Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
Mototani H, Iida A, Nakamura Y, Ikegawa S
J Bone Miner Metab. 2010
PubMed ID: 20198394
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells.
Heibeck TH, Ding SJ, Opresko LK, Zhao R, Schepmoes AA, Yang F, Tolmachev AV, Monroe ME, Camp DG, Smith RD, Wiley HS, Qian WJ
J Proteome Res. 2009
PubMed ID: 19534553
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S
JAMA. 2009
PubMed ID: 19584346
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes.
Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT
Mol Cell Biol. 2009
PubMed ID: 19188439
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK
Sci Signal. 2009
PubMed ID: 19690332
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
S100A1 and calmodulin compete for the same binding site on ryanodine receptor.
Wright NT, Prosser BL, Varney KM, Zimmer DB, Schneider MF, Weber DJ
J Biol Chem. 2008
PubMed ID: 18650434
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
Ballif BA, Carey GR, Sunyaev SR, Gygi SP
J Proteome Res. 2008
PubMed ID: 18034455
Rad GTPase deficiency leads to cardiac hypertrophy.
Chang L, Zhang J, Tseng YH, Xie CQ, Ilany J, Brüning JC, Sun Z, Zhu X, Cui T, Youker KA, Yang Q, Day SM, Kahn CR, Chen YE
Circulation. 2007
PubMed ID: 18056528
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
Cell. 2007
PubMed ID: 18083107
Cep97 and CP110 suppress a cilia assembly program.
Spektor A, Tsang WY, Khoo D, Dynlacht BD
Cell. 2007
PubMed ID: 17719545
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks.
Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17389395
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.
Molina H, Horn DM, Tang N, Mathivanan S, Pandey A
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17287340
The association of common polymorphisms in the QPCT gene with bone mineral density in the Chinese population.
Huang QY, Kung AW
J Hum Genet. 2007
PubMed ID: 17687619
Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features.
Houdusse A, Gaucher JF, Krementsova E, Mui S, Trybus KM, Cohen C
Proc Natl Acad Sci U S A. 2006
PubMed ID: 17151196
HIV-1 Nef upregulates CCL2/MCP-1 expression in astrocytes in a myristoylation- and calmodulin-dependent manner.
Lehmann MH, Masanetz S, Kramer S, Erfle V
J Cell Sci. 2006
PubMed ID: 17046994
CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.
Tsang WY, Spektor A, Luciano DJ, Indjeian VB, Chen Z, Salisbury JL, Sánchez I, Dynlacht BD
Mol Biol Cell. 2006
PubMed ID: 16760425
The complexity of antisense transcription revealed by the study of developing male germ cells.
Chan WY, Wu SM, Ruszczyk L, Law E, Lee TL, Baxendale V, Lap-Yin Pang A, Rennert OM
Genomics. 2006
PubMed ID: 16458478
Involvement of calmodulin in neuronal cell death.
Shirasaki Y, Kanazawa Y, Morishima Y, Makino M
Brain Res. 2006
PubMed ID: 16545345
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Point mutations in the C-terminus of HIV-1 gp160 reduce apoptosis and calmodulin binding without affecting viral replication.
Micoli KJ, Mamaeva O, Piller SC, Barker JL, Pan G, Hunter E, McDonald JM
Virology. 2006
PubMed ID: 16229872
Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains.
Farber CR, Corva PM, Medrano JF
BMC Genomics. 2006
PubMed ID: 16670015
Non-equivalence of embryonic and somatic cell nuclei affecting spindle composition in clones.
Miyara F, Han Z, Gao S, Vassena R, Latham KE
Dev Biol. 2006
PubMed ID: 16310175
Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex.
Van Petegem F, Chatelain FC, Minor DL
Nat Struct Mol Biol. 2005
PubMed ID: 16299511
Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6.
Shen C, Ye Y, Robertson SE, Lau AW, Mak DO, Chou MM
J Biol Chem. 2005
PubMed ID: 16127172
Towards a proteome-scale map of the human protein-protein interaction network.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M
Nature. 2005
PubMed ID: 16189514
Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.
Jung SY, Malovannaya A, Wei J, O'Malley BW, Qin J
Mol Endocrinol. 2005
PubMed ID: 16051665
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal.
Sim H, Rimmer K, Kelly S, Ludbrook LM, Clayton AH, Harley VR
Mol Endocrinol. 2005
PubMed ID: 15746192
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Kremitzki C, Oddy L, Du H, Sun H, Bradshaw-Cordum H, Ali J, Carter J, Cordes M, Harris A, Isak A, van Brunt A, Nguyen C, Du F, Courtney L, Kalicki J, Ozersky P, Abbott S, Armstrong J, Belter EA, Caruso L, Cedroni M, Cotton M, Davidson T, Desai A, Elliott G, Erb T, Fronick C, Gaige T, Haakenson W, Haglund K, Holmes A, Harkins R, Kim K, Kruchowski SS, Strong CM, Grewal N, Goyea E, Hou S, Levy A, Martinka S, Mead K, McLellan MD, Meyer R, Randall-Maher J, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Shah N, Swearengen-Shahid S, Snider J, Strong JT, Thompson J, Yoakum M, Leonard S, Pearman C, Trani L, Radionenko M, Waligorski JE, Wang C, Rock SM, Tin-Wollam AM, Maupin R, Latreille P, Wendl MC, Yang SP, Pohl C, Wallis JW, Spieth J, Bieri TA, Berkowicz N, Nelson JO, Osborne J, Ding L, Meyer R, Sabo A, Shotland Y, Sinha P, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Jones TA, She X, Ciccarelli FD, Izaurralde E, Taylor J, Schmutz J, Myers RM, Cox DR, Huang X, McPherson JD, Mardis ER, Clifton SW, Warren WC, Chinwalla AT, Eddy SR, Marra MA, Ovcharenko I, Furey TS, Miller W, Eichler EE, Bork P, Suyama M, Torrents D, Waterston RH, Wilson RK
Nature. 2005
PubMed ID: 15815621
Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
Shen Y, Zhukovskaya NL, Guo Q, Florián J, Tang WJ
EMBO J. 2005
PubMed ID: 15719022
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin.
Otto EA, Loeys B, Khanna H, Hellemans J, Sudbrak R, Fan S, Muerb U, O'Toole JF, Helou J, Attanasio M, Utsch B, Sayer JA, Lillo C, Jimeno D, Coucke P, De Paepe A, Reinhardt R, Klages S, Tsuda M, Kawakami I, Kusakabe T, Omran H, Imm A, Tippens M, Raymond PA, Hill J, Beales P, He S, Kispert A, Margolis B, Williams DS, Swaroop A, Hildebrandt F
Nat Genet. 2005
PubMed ID: 15723066
Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo.
Matsubara M, Jing T, Kawamura K, Shimojo N, Titani K, Hashimoto K, Hayashi N
Protein Sci. 2005
PubMed ID: 15632291
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ
Nat Biotechnol. 2005
PubMed ID: 15592455
A network of control mediated by regulator of calcium/calmodulin-dependent signaling.
Rakhilin SV, Olson PA, Nishi A, Starkova NN, Fienberg AA, Nairn AC, Surmeier DJ, Greengard P
Science. 2004
PubMed ID: 15499021
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S
Genome Res. 2004
PubMed ID: 15342556
Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity.
Junge HJ, Rhee JS, Jahn O, Varoqueaux F, Spiess J, Waxham MN, Rosenmund C, Brose N
Cell. 2004
PubMed ID: 15294163
Cell type-specific regulation of calmodulin 2 expression by mutant p53.
Knaup KX, Roemer K
FEBS Lett. 2004
PubMed ID: 15225611
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Endofin recruits TOM1 to endosomes.
Seet LF, Liu N, Hanson BJ, Hong W
J Biol Chem. 2004
PubMed ID: 14613930
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
Recombinant expression, purification and characterisation of the HMG domain of human SRY.
Kelly S, Yotis J, Macris M, Harley V
Protein Pept Lett. 2003
PubMed ID: 12871148
Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin.
Yamauchi E, Nakatsu T, Matsubara M, Kato H, Taniguchi H
Nat Struct Biol. 2003
PubMed ID: 12577052
The DNA sequence and analysis of human chromosome 14.
Heilig R, Eckenberg R, Petit JL, Fonknechten N, Da Silva C, Cattolico L, Levy M, Barbe V, de Berardinis V, Ureta-Vidal A, Pelletier E, Vico V, Anthouard V, Rowen L, Madan A, Qin S, Sun H, Du H, Pepin K, Artiguenave F, Robert C, Cruaud C, Brüls T, Jaillon O, Friedlander L, Samson G, Brottier P, Cure S, Ségurens B, Anière F, Samain S, Crespeau H, Abbasi N, Aiach N, Boscus D, Dickhoff R, Dors M, Dubois I, Friedman C, Gouyvenoux M, James R, Madan A, Mairey-Estrada B, Mangenot S, Martins N, Ménard M, Oztas S, Ratcliffe A, Shaffer T, Trask B, Vacherie B, Bellemere C, Belser C, Besnard-Gonnet M, Bartol-Mavel D, Boutard M, Briez-Silla S, Combette S, Dufossé-Laurent V, Ferron C, Lechaplais C, Louesse C, Muselet D, Magdelenat G, Pateau E, Petit E, Sirvain-Trukniewicz P, Trybou A, Vega-Czarny N, Bataille E, Bluet E, Bordelais I, Dubois M, Dumont C, Guérin T, Haffray S, Hammadi R, Muanga J, Pellouin V, Robert D, Wunderle E, Gauguet G, Roy A, Sainte-Marthe L, Verdier J, Verdier-Discala C, Hillier L, Fulton L, McPherson J, Matsuda F, Wilson R, Scarpelli C, Gyapay G, Wincker P, Saurin W, Quétier F, Waterston R, Hood L, Weissenbach J
Nature. 2003
PubMed ID: 12508121
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins.
Shen Y, Lee YS, Soelaiman S, Bergson P, Lu D, Chen A, Beckingham K, Grabarek Z, Mrksich M, Tang WJ
EMBO J. 2002
PubMed ID: 12485993
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Phosphorylation of calmodulin by Ca2+/calmodulin-dependent protein kinase IV.
Ishida A, Kameshita I, Okuno S, Kitani T, Fujisawa H
Arch Biochem Biophys. 2002
PubMed ID: 12392717
Formation of complexes between Ca2+.calmodulin and the synapse-associated protein SAP97 requires the SH3 domain-guanylate kinase domain-connecting HOOK region.
Paarmann I, Spangenberg O, Lavie A, Konrad M
J Biol Chem. 2002
PubMed ID: 12189141
Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock.
Craig DH, Chapman SK, Daff S
J Biol Chem. 2002
PubMed ID: 12089147
Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.
Takahashi M, Yamagiwa A, Nishimura T, Mukai H, Ono Y
Mol Biol Cell. 2002
PubMed ID: 12221128
The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels.
Yus-Najera E, Santana-Castro I, Villarroel A
J Biol Chem. 2002
PubMed ID: 12032157
Phosphorylation of calmodulin. Functional implications.
Benaim G, Villalobo A
Eur J Biochem. 2002
PubMed ID: 12153558
Protein Ser/Thr phosphatases PPEF interact with calmodulin.
Kutuzov MA, Solov'eva OV, Andreeva AV, Bennett N
Biochem Biophys Res Commun. 2002
PubMed ID: 12051765
Calmodulin is a selective modulator of estrogen receptors.
García Pedrero JM, Del Rio B, Martínez-Campa C, Muramatsu M, Lazo PS, Ramos S
Mol Endocrinol. 2002
PubMed ID: 11981030
Interaction between metabotropic glutamate receptor 7 and alpha tubulin.
Saugstad JA, Yang S, Pohl J, Hall RA, Conn PJ
J Neurochem. 2002
PubMed ID: 11953448
Evidence for the direct interaction between calmodulin and the human epidermal growth factor receptor.
Li H, Villalobo A
Biochem J. 2002
PubMed ID: 11853560
Nef of HIV-1 interacts directly with calcium-bound calmodulin.
Hayashi N, Matsubara M, Jinbo Y, Titani K, Izumi Y, Matsushima N
Protein Sci. 2002
PubMed ID: 11847276
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ
Nature. 2002
PubMed ID: 11807546
Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin.
Sidhu RS, Bhullar RP
Biochem Biophys Res Commun. 2001
PubMed ID: 11741295
Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains.
Chou JJ, Li S, Klee CB, Bax A
Nat Struct Biol. 2001
PubMed ID: 11685248
The plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I.
Schuh K, Uldrijan S, Telkamp M, Rothlein N, Neyses L
J Cell Biol. 2001
PubMed ID: 11591728
Some properties of caldesmon and calponin and the participation of these proteins in regulation of smooth muscle contraction and cytoskeleton formation.
Gusev NB
Biochemistry (Mosc). 2001
PubMed ID: 11736632
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Schumacher MA, Rivard AF, Bächinger HP, Adelman JP
Nature. 2001
PubMed ID: 11323678
The sequence of the human genome.
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X
Science. 2001
PubMed ID: 11181995
The effects of aging on gene expression in the hypothalamus and cortex of mice.
Jiang CH, Tsien JZ, Schultz PG, Hu Y
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11172053
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Calmodulin binding properties of peptide analogues and fragments of the calmodulin-binding domain of simian immunodeficiency virus transmembrane glycoprotein 41.
Yuan T, Tencza S, Mietzner TA, Montelaro RC, Vogel HJ
Biopolymers. 2001
PubMed ID: 11072229
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Calmodulin and HIV type 1: interactions with Gag and Gag products.
Radding W, Williams JP, McKenna MA, Tummala R, Hunter E, Tytler EM, McDonald JM
AIDS Res Hum Retroviruses. 2000
PubMed ID: 11054265
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Interaction between endothelial differentiation-related factor-1 and calmodulin in vitro and in vivo.
Mariotti M, De Benedictis L, Avon E, Maier JA
J Biol Chem. 2000
PubMed ID: 10816571
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Calmodulin regulation of basal and agonist-stimulated G protein coupling by the mu-opioid receptor (OP(3)) in morphine-pretreated cell.
Wang D, Surratt CK, Sadée W
J Neurochem. 2000
PubMed ID: 10899953
Identification of a human centrosomal calmodulin-binding protein that shares homology with pericentrin.
Flory MR, Moser MJ, Monnat RJ, Davis TN
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10823944
A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors.
Onions J, Hermann S, Grundström T
Biochemistry. 2000
PubMed ID: 10757985
Ca(2+)-dependent and Ca(2+)-independent calmodulin binding sites in erythrocyte protein 4.1. Implications for regulation of protein 4.1 interactions with transmembrane proteins.
Nunomura W, Takakuwa Y, Parra M, Conboy JG, Mohandas N
J Biol Chem. 2000
PubMed ID: 10692436
Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis.
Micoli KJ, Pan G, Wu Y, Williams JP, Cook WJ, McDonald JM
J Biol Chem. 2000
PubMed ID: 10625668
Study of the gerbil utricular macula following treatment with gentamicin, by use of bromodeoxyuridine and calmodulin immunohistochemical labelling.
Ogata Y, Slepecky NB, Takahashi M
Hear Res. 1999
PubMed ID: 10416864
Calmodulin-binding sites on adenylyl cyclase type VIII.
Gu C, Cooper DM
J Biol Chem. 1999
PubMed ID: 10075700
Alpha-helix nucleation by a calcium-binding peptide loop.
Siedlecka M, Goch G, Ejchart A, Sticht H, Bierzyski A
Proc Natl Acad Sci U S A. 1999
PubMed ID: 9927666
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Structural basis for activation of the titin kinase domain during myofibrillogenesis.
Mayans O, van der Ven PF, Wilm M, Mues A, Young P, Fürst DO, Wilmanns M, Gautel M
Nature. 1998
PubMed ID: 9804419
Apoptosis induction by the binding of the carboxyl terminus of human immunodeficiency virus type 1 gp160 to calmodulin.
Ishikawa H, Sasaki M, Noda S, Koga Y
J Virol. 1998
PubMed ID: 9658102
Characterization of the human CALM2 calmodulin gene and comparison of the transcriptional activity of CALM1, CALM2 and CALM3.
Toutenhoofd SL, Foletti D, Wicki R, Rhyner JA, Garcia F, Tolon R, Strehler EE
Cell Calcium. 1998
PubMed ID: 9681195
Molecular mechanisms of calmodulin's functional versatility.
Zhang M, Yuan T
Biochem Cell Biol. 1998
PubMed ID: 9923700
Signal peptide fragments of preprolactin and HIV-1 p-gp160 interact with calmodulin.
Martoglio B, Graf R, Dobberstein B
EMBO J. 1997
PubMed ID: 9362478
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin.
Miyawaki A, Llopis J, Heim R, McCaffery JM, Adams JA, Ikura M, Tsien RY
Nature. 1997
PubMed ID: 9278050
Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro.
Minakami R, Jinnai N, Sugiyama H
J Biol Chem. 1997
PubMed ID: 9242710
A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells.
Arnold DB, Heintz N
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9238065
Inhibition of HIV-1, HIV-2 and SIV envelope glycoprotein-mediated cell fusion by calmodulin.
Malvoisin E, Wild F
Virus Res. 1997
PubMed ID: 9282777
Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway.
Brigino E, Haraguchi S, Koutsonikolis A, Cianciolo GJ, Owens U, Good RA, Day NK
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9096366
Induction of apoptosis by calmodulin-dependent intracellular Ca2+ elevation in CD4+ cells expressing gp 160 of HIV.
Sasaki M, Uchiyama J, Ishikawa H, Matsushita S, Kimura G, Nomoto K, Koga Y
Virology. 1996
PubMed ID: 8862395
Role of calmodulin in HIV-potentiated Fas-mediated apoptosis.
Pan Z, Radding W, Zhou T, Hunter E, Mountz J, McDonald JM
Am J Pathol. 1996
PubMed ID: 8780394
Expression of HIV-1 envelope glycoprotein alters cellular calmodulin.
Radding W, Pan ZQ, Hunter E, Johnston P, Williams JP, McDonald JM
Biochem Biophys Res Commun. 1996
PubMed ID: 8573130
Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.
Harrison SM, Dunwoodie SL, Arkell RM, Lehrach H, Beddington RS
Development. 1995
PubMed ID: 7671812
Three different calmodulin-encoding cDNAs isolated by a modified 5'-RACE using degenerate oligodeoxyribonucleotides.
Skinner TL, Kerns RT, Bender PK
Gene. 1994
PubMed ID: 7828884
Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex.
Cook WJ, Walter LJ, Walter MR
Biochemistry. 1994
PubMed ID: 7803388
Structure of the human CALM1 calmodulin gene and identification of two CALM1-related pseudogenes CALM1P1 and CALM1P2.
Rhyner JA, Ottiger M, Wicki R, Greenwood TM, Strehler EE
Eur J Biochem. 1994
PubMed ID: 7925473
The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression.
Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K
Gene. 1994
PubMed ID: 8076819
Identification of a calmodulin-binding and inhibitory peptide domain in the HIV-1 transmembrane glycoprotein.
Miller MA, Mietzner TA, Cloyd MW, Robey WG, Montelaro RC
AIDS Res Hum Retroviruses. 1993
PubMed ID: 8312049
Cytosolic domain of the human immunodeficiency virus envelope glycoproteins binds to calmodulin and inhibits calmodulin-regulated proteins.
Srinivas SK, Srinivas RV, Anantharamaiah GM, Compans RW, Segrest JP
J Biol Chem. 1993
PubMed ID: 8226798
Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3.
Berchtold MW, Egli R, Rhyner JA, Hameister H, Strehler EE
Genomics. 1993
PubMed ID: 8314583
Calmodulin structure refined at 1.7 A resolution.
Chattopadhyaya R, Meador WE, Means AR, Quiocho FA
J Mol Biol. 1992
PubMed ID: 1474585
Molecular cloning of calmodulin mRNA species which are preferentially expressed in neurons in the rat brain.
Ni B, Rush S, Gurd JW, Brown IR
Brain Res Mol Brain Res. 1992
PubMed ID: 1315919
Structural organization of the human CaMIII calmodulin gene.
Koller M, Schnyder B, Strehler EE
Biochim Biophys Acta. 1990
PubMed ID: 2223880
A Collection of cDNA Clones with Specific Expression Patterns in Mouse Brain.
Kato K
Eur J Neurosci. 1990
PubMed ID: 12106288
Cloning and expression of mouse-brain calmodulin as an activator of Bordetella pertussis adenylate cyclase in Escherichia coli.
Danchin A, Sezer O, Glaser P, Chalon P, Caput D
Gene. 1989
PubMed ID: 2551780
Structural organization of multiple rat calmodulin genes.
Nojima H
J Mol Biol. 1989
PubMed ID: 2527998
Calmodulin is required for cell-cycle progression during G1 and mitosis.
Rasmussen CD, Means AR
EMBO J. 1989
PubMed ID: 2469574
Multiple divergent mRNAs code for a single human calmodulin.
Fischer R, Koller M, Flura M, Mathews S, Strehler-Page MA, Krebs J, Penniston JT, Carafoli E, Strehler EE
J Biol Chem. 1988
PubMed ID: 3182832
Structure of calmodulin refined at 2.2 A resolution.
Babu YS, Bugg CE, Cook WJ
J Mol Biol. 1988
PubMed ID: 3145979
The abundance of calmodulin mRNAs is regulated in phosphorylase kinase-deficient skeletal muscle.
Bender PK, Dedman JR, Emerson CP
J Biol Chem. 1988
PubMed ID: 3384819
Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species.
SenGupta B, Friedberg F, Detera-Wadleigh SD
J Biol Chem. 1987
PubMed ID: 2445749
Rat calmodulin cDNA.
Sherbany AA, Parent AS, Brosius J
DNA. 1987
PubMed ID: 2885164
Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C.
Baudier J, Mochly-Rosen D, Newton A, Lee SH, Koshland DE, Cole RD
Biochemistry. 1987
PubMed ID: 3111527
Multiple calmodulin mRNA species are derived from two distinct genes.
Nojima H, Kishi K, Sokabe H
Mol Cell Biol. 1987
PubMed ID: 3037336
Structure of a gene for rat calmodulin.
Nojima H, Sokabe H
J Mol Biol. 1987
PubMed ID: 3035194
Three-dimensional structure of calmodulin.
Babu YS, Sack JS, Greenhough TJ, Bugg CE, Means AR, Cook WJ
Nature. 1985
PubMed ID: 3990807
Isolation and nucleotide sequence of a cDNA encoding human calmodulin.
Wawrzynczak EJ, Perham RN
Biochem Int. 1984
PubMed ID: 6385987
Complete amino acid sequence of human brain calmodulin.
Sasagawa T, Ericsson LH, Walsh KA, Schreiber WE, Fischer EH, Titani K
Biochemistry. 1982
PubMed ID: 7093203
Sequence homology of the Ca2+-dependent regulator of cyclic nucleotide phosphodiesterase from rat testis with other Ca2+-binding proteins.
Dedman JR, Jackson RL, Schreiber WE, Means AR
J Biol Chem. 1978
PubMed ID: 201628

Model Organism Phenotype Links from MGI Top Help

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	Human	Mouse	Rat
Entrez Gene	805	12314	50663
EnsEMBL Gene(s)	ENSG00000143933 ENSG00000160014 ENSG00000198668	ENSMUSG00000001175 ENSMUSG00000019370 ENSMUSG00000036438	ENSRNOG00000004060 ENSRNOG00000016770
Unigene	Hs.468442	Mm.329243	Rn.5968
Homologene	CALM2	Calm2	Calm2
OMIM	114182	N/A	N/A
GeneCards	CALM2	N/A	N/A
Beta Cell Genomics	DT.100719674 DT.100719692 DT.100719696 DT.100719701 DT.87012055 DT.87017757 DT.91784270 DT.91790606 DT.91881591 DT.92352590 DT.95294800 DT.95319794	DT.101361689 DT.110563372 DT.55224918 DT.60118659 DT.94375743 DT.94375793 DT.97369120	N/A
Reactome	P62158	N/A	N/A
Plasma Peptide Atlas	ENSP00000272298	N/A	N/A
WikiGenes	805	12314	50663

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