KCNAB1

Summary Top Help

Gene Description:

potassium voltage-gated channel, shaker-related subfamily, beta member 1

Synonyms:

Kvbeta1.1, hKvb3, Akr8a8, AKR6A3, mKv(beta)1, KV-BETA-1, Kvb1.3, KCNAB1, KvBeta3, KCNA1B, Kcnab1, hKvBeta3

Orthologs:

Human KCNAB1 (protein-coding), Mouse Kcnab1 (protein-coding), Rat Kcnab1 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr3:155755490..156256927 (501.44 kb) View in Genome Browser

(Mouse) NCBIM37 - chr3:64913306..65182145 (268.84 kb) View in Genome Browser

(Rat) RGSC3.4 - chr2:154837841..155145882 (3084 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for KCNAB1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for KCNAB1:

The KCNAB1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.

The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.

Interactor	Interactor	Sources	Classification	Pubmed IDs
KCNAB1	KCNH8	Reactome	predicted
KCNAB1	KCNV2	Reactome	predicted
KCNAB1	KCNG3	Reactome	predicted
KCNAB1	DLG1	HPRD	empirical	9341123
KCNAB1	DLG4	IntAct	empirical	19455133
KCNAB1	NEDD4L	BioGRID	empirical	19953087
KCNAB1	KCNH4	Reactome	predicted
KCNAB1	KCNH3	Reactome	predicted
KCNAB1	KPNA6	Sanger Interaction Map	predicted	15345047
KCNAB1	KCNG2	Reactome	predicted
KCNAB1	KCNV1	Reactome	predicted
KCNAB1	KCNH5	Reactome	predicted
KCNAB1	SLC39A1	HPRD	empirical	10477520
KCNAB1	SLC39A2	HPRD	empirical	10477520
KCNAB1	KCNA1	MIPS, Reactome	empirical	9334400
KCNAB1	KCNA2	HPRD, MIPS, BioGRID, Reactome	empirical	11401852 8636142 9334400
KCNAB1	KCNA3	Reactome	predicted
KCNAB1	KCNA4	MIPS, Reactome	empirical	9334400
KCNAB1	KCNA5	Reactome	predicted
KCNAB1	KCNA6	MIPS, Reactome	empirical	9334400
KCNAB1	KCNA7	Reactome	predicted
KCNAB1	KCNA10	Reactome	predicted
KCNAB1	KCNB1	Reactome	predicted
KCNAB1	KCNC1	Reactome	predicted
KCNAB1	KCNC2	Reactome	predicted
KCNAB1	KCNC3	Reactome	predicted
KCNAB1	KCNC4	Reactome	predicted
KCNAB1	KCND1	Reactome	predicted
KCNAB1	KCND2	Reactome	predicted
KCNAB1	KCND3	Reactome	predicted
KCNAB1	KCNF1	Reactome	predicted
KCNAB1	KCNG1	Reactome	predicted
KCNAB1	KCNH1	Reactome	predicted
KCNAB1	KCNH2	Reactome	predicted
KCNAB1	KCNQ1	Reactome	predicted
KCNAB1	KCNQ2	Reactome	predicted
KCNAB1	KCNQ3	Reactome	predicted
KCNAB1	KCNS1	Reactome	predicted
KCNAB1	KCNS2	Reactome	predicted
KCNAB1	KCNS3	Reactome	predicted
KCNAB1	ARRB2	IntAct	empirical	17620599
KCNAB1	NEDD4	BioGRID	empirical	19953087
KCNAB1	KCNQ5	Reactome	predicted
KCNAB1	SNCA	IntAct	empirical	18614564
KCNAB1	KCNH6	Reactome	predicted
KCNAB1	KCNAB2	MIPS	empirical	9334400
KCNAB1	KCNH7	Reactome	predicted
KCNAB1	KCNQ4	Reactome	predicted
KCNAB1	KCNG4	Reactome	predicted
KCNAB1	KCNB2	Reactome	predicted

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 10

Publications from PubMed Top Help

Publications: 56

Association of intronic variants of the KCNAB1 gene with lateral temporal epilepsy.
Busolin G, Malacrida S, Bisulli F, Striano P, Di Bonaventura C, Egeo G, Pasini E, Cianci V, Ferlazzo E, Bianchi A, Coppola G, Elia M, Mecarelli O, Gobbi G, Casellato S, Marchini M, Binelli S, Freri E, Granata T, Posar A, Parmeggiani A, Vigliano P, Boniver C, Aguglia U, Striano S, Tinuper P, Giallonardo AT, Michelucci R, Nobile C
Epilepsy Res. 2011
PubMed ID: 21333500
Investigation of genetic susceptibility factors for human longevity - A targeted nonsynonymous SNP study.
Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A
Mutat Res. 2010
PubMed ID: 20800603
Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation.
Chiu HS, Szucsik JC, Georgas KM, Jones JL, Rumballe BA, Tang D, Grimmond SM, Lewis AG, Aronow BJ, Lessard JL, Little MH
Dev Biol. 2010
PubMed ID: 20510229
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentials.
Bunse S, Locovei S, Schmidt M, Qiu F, Zoidl G, Dahl G, Dermietzel R
FEBS J. 2009
PubMed ID: 19780818
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.
Decher N, Gonzalez T, Streit AK, Sachse FB, Renigunta V, Soom M, Heinemann SH, Daut J, Sanguinetti MC
EMBO J. 2008
PubMed ID: 18987637
Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Pan Y, Weng J, Kabaleeswaran V, Li H, Cao Y, Bhosle RC, Zhou M
Nat Chem Biol. 2008
PubMed ID: 18806782
Structural determinants of monohydroxylated bile acids to activate beta 1 subunit-containing BK channels.
Bukiya AN, McMillan J, Parrill AL, Dopico AM
J Lipid Res. 2008
PubMed ID: 18650555
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions.
McFarland MA, Ellis CE, Markey SP, Nussbaum RL
Mol Cell Proteomics. 2008
PubMed ID: 18614564
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Functional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1.
Pan Y, Weng J, Cao Y, Bhosle RC, Zhou M
J Biol Chem. 2008
PubMed ID: 18222921
Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study.
Cavalleri GL, Weale ME, Shianna KV, Singh R, Lynch JM, Grinton B, Szoeke C, Murphy K, Kinirons P, O'Rourke D, Ge D, Depondt C, Claeys KG, Pandolfo M, Gumbs C, Walley N, McNamara J, Mulley JC, Linney KN, Sheffield LJ, Radtke RA, Tate SK, Chissoe SL, Gibson RA, Hosford D, Stanton A, Graves TD, Hanna MG, Eriksson K, Kantanen AM, Kalviainen R, O'Brien TJ, Sander JW, Duncan JS, Scheffer IE, Berkovic SF, Wood NW, Doherty CP, Delanty N, Sisodiya SM, Goldstein DB
Lancet Neurol. 2007
PubMed ID: 17913586
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Lamesch P, Li N, Milstein S, Fan C, Hao T, Szabo G, Hu Z, Venkatesan K, Bethel G, Martin P, Rogers J, Lawlor S, McLaren S, Dricot A, Borick H, Cusick ME, Vandenhaute J, Dunham I, Hill DE, Vidal M
Genomics. 2007
PubMed ID: 17207965
Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.
Harrell MD, Harbi S, Hoffman JF, Zavadil J, Coetzee WA
Physiol Genomics. 2007
PubMed ID: 16985003
Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.
Lunetta KL, D'Agostino RB, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM
BMC Med Genet. 2007
PubMed ID: 17903295
The DNA sequence, annotation and analysis of human chromosome 3.
Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA
Nature. 2006
PubMed ID: 16641997
The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.
Schulte U, Thumfart JO, Klöcker N, Sailer CA, Bildl W, Biniossek M, Dehn D, Deller T, Eble S, Abbass K, Wangler T, Knaus HG, Fakler B
Neuron. 2006
PubMed ID: 16504945
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.
Aimond F, Kwak SP, Rhodes KJ, Nerbonne JM
Circ Res. 2005
PubMed ID: 15662035
Genetic modifiers of the Kv beta2-null phenotype in mice.
Connor JX, McCormack K, Pletsch A, Gaeta S, Ganetzky B, Chiu SY, Messing A
Genes Brain Behav. 2005
PubMed ID: 15720404
Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice.
Murphy GG, Fedorov NB, Giese KP, Ohno M, Friedman E, Chen R, Silva AJ
Curr Biol. 2004
PubMed ID: 15530391
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization.
Nie DY, Zhou ZH, Ang BT, Teng FY, Xu G, Xiang T, Wang CY, Zeng L, Takeda Y, Xu TL, Ng YK, Faivre-Sarrailh C, Popko B, Ling EA, Schachner M, Watanabe K, Pallen CJ, Tang BL, Xiao ZC
EMBO J. 2003
PubMed ID: 14592966
Learning and memory impairments in Kv beta 1.1-null mutants are rescued by environmental enrichment or ageing.
Need AC, Irvine EE, Giese KP
Eur J Neurosci. 2003
PubMed ID: 14511342
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression.
Kuryshev YA, Wible BA, Gudz TI, Ramirez AN, Brown AM
Am J Physiol Cell Physiol. 2001
PubMed ID: 11401852
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Dissection of behavior and psychiatric disorders using the mouse as a model.
Tarantino LM, Bucan M
Hum Mol Genet. 2000
PubMed ID: 10767319
Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries.
Suzuki Y, Ishihara D, Sasaki M, Nakagawa H, Hata H, Tsunoda T, Watanabe M, Komatsu T, Ota T, Isogai T, Suyama A, Sugano S
Genomics. 2000
PubMed ID: 10756096
Developmental expression of voltage-gated potassium channel beta subunits.
Downen M, Belkowski S, Knowles H, Cardillo M, Prystowsky MB
Brain Res Dev Brain Res. 1999
PubMed ID: 10536234
Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.
Gong J, Xu J, Bezanilla M, van Huizen R, Derin R, Li M
Science. 1999
PubMed ID: 10477520
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel.
Leicher T, Bähring R, Isbrandt D, Pongs O
J Biol Chem. 1998
PubMed ID: 9857044
Reduced K+ channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning.
Giese KP, Storm JF, Reuter D, Fedorov NB, Shao LR, Leicher T, Pongs O, Silva AJ
Learn Mem. 1998
PubMed ID: 10454353
Genetic mapping of the voltage-gated shaker potassium channel beta subunit Kcnab1 to mouse chromosome 3.
Jones JM, Bentley E, Meisler MH, Darling SM
Mamm Genome. 1998
PubMed ID: 9501317
Mouse brain potassium channel beta1 subunit mRNA: cloning and distribution during development.
Butler DM, Ono JK, Chang T, McCaman RE, Barish ME
J Neurobiol. 1998
PubMed ID: 9468385
Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes.
Hanada T, Lin L, Chandy KG, Oh SS, Chishti AH
J Biol Chem. 1997
PubMed ID: 9341123
A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression.
Fink M, Duprat F, Lesage F, Heurteaux C, Romey G, Barhanin J, Lazdunski M
J Biol Chem. 1996
PubMed ID: 8824288
Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits.
Nakahira K, Shi G, Rhodes KJ, Trimmer JS
J Biol Chem. 1996
PubMed ID: 8636142
Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B.
Schultz D, Litt M, Smith L, Thayer M, McCormack K
Genomics. 1996
PubMed ID: 8838324
Structural and functional characterization of human potassium channel subunit beta 1 (KCNA1B).
Leicher T, Roeper J, Weber K, Wang X, Pongs O
Neuropharmacology. 1996
PubMed ID: 8938711
A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing.
England SK, Uebele VN, Kodali J, Bennett PB, Tamkun MM
J Biol Chem. 1995
PubMed ID: 7499366
Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product.
McCormack K, McCormack T, Tanouye M, Rudy B, Stühmer W
FEBS Lett. 1995
PubMed ID: 7649300
Characterization of a voltage-gated K+ channel beta subunit expressed in human heart.
England SK, Uebele VN, Shear H, Kodali J, Bennett PB, Tamkun MM
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7603988
A novel beta subunit increases rate of inactivation of specific voltage-gated potassium channel alpha subunits.
Morales MJ, Castellino RC, Crews AL, Rasmusson RL, Strauss HC
J Biol Chem. 1995
PubMed ID: 7890764
Molecular cloning and functional expression of a novel potassium channel beta-subunit from human atrium.
Majumder K, De Biasi M, Wang Z, Wible BA
FEBS Lett. 1995
PubMed ID: 7890032
Shaker K+ channel beta subunits belong to an NAD(P)H-dependent oxidoreductase superfamily.
McCormack T, McCormack K
Cell. 1994
PubMed ID: 8001150
Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit.
Rettig J, Heinemann SH, Wunder F, Lorra C, Parcej DN, Dolly JO, Pongs O
Nature. 1994
PubMed ID: 8183366
Primary structure of a beta subunit of alpha-dendrotoxin-sensitive K+ channels from bovine brain.
Scott VE, Rettig J, Parcej DN, Keen JN, Findlay JB, Pongs O, Dolly JO
Proc Natl Acad Sci U S A. 1994
PubMed ID: 8127858

Model Organism Phenotype Links from MGI Top Help

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	Human	Mouse	Rat
Entrez Gene	7881	16497	29737
EnsEMBL Gene(s)	ENSG00000169282	ENSMUSG00000027827	ENSRNOG00000010422
Unigene	Hs.654519	Mm.316402	Rn.32090
Homologene	KCNAB1	Kcnab1	Kcnab1
OMIM	601141	N/A	N/A
GeneCards	KCNAB1	N/A	N/A
Beta Cell Genomics	DT.100678459 DT.100743432 DT.120847313 DT.414830 DT.95160478	DT.101371997 DT.101371998 DT.101707013 DT.60117371 DT.94259608 DT.97363640	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	7881	16497	29737

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