Home TXN
|
(Human) GRCh37 - chr9:113006091..113018920 (12.83 kb) View in Genome Browser
(Mouse) NCBIM37 - chr4:57956245..57969283 (134 kb) View in Genome Browser
(Rat) RGSC3.4 - chr5:75921316..75933680 (12.36 kb) View in Genome Browser
HaemAtlas Expression Table for TXN:|
Expression Legend
|
|
|
Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
Expression Legend
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Expression Legend
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for TXN:The TXN interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| TXN | CDKN1A | IntAct | empirical | 21988832 |
| TXN | EIF1B | IntAct | empirical | 17353931 |
| TXN | FST | BioGRID | empirical | 12099690 |
| TXN | TXNIP | HPRD, IntAct, BioGRID, Reactome | empirical | 10419473 10814541 17603038 |
| TXN | COPS5 | HPRD, IntAct | empirical | 15480426 |
| TXN | FAM107A | IntAct | empirical | 17353931 |
| TXN | GABARAP | IntAct | empirical | 20562859 |
| TXN | GABARAPL2 | IntAct | empirical | 20562859 |
| TXN | COL1A1 | HPRD, BioGRID | empirical | 12099690 |
| TXN | DLG4 | IntAct | empirical | 19455133 |
| TXN | EGFR | IntAct | empirical | 20029029 15657067 |
| TXN | EPB41 | IntAct | empirical | 17353931 |
| TXN | GABARAPL1 | IntAct | empirical | 20562859 |
| TXN | GAPDH | IntAct, BioGRID | empirical | 17353931 |
| TXN | GFER | HPRD | empirical | 15894171 |
| TXN | NR3C1 | HPRD, BioGRID | empirical | 9915858 |
| TXN | HLA-B | IntAct | empirical | 17353931 |
| TXN | HMGB1 | MINT | empirical | 18996119 |
| TXN | APEX1 | HPRD | empirical | 11118054 10585464 9108029 |
| TXN | DNAJA1 | HPRD | empirical | 16458196 |
| TXN | IFIT3 | IntAct | empirical | 21642987 |
| TXN | MAP3K5 | HPRD, IntAct, BioGRID | empirical | 12089063 9564042 21771788 11689443 |
| TXN | MLH1 | IntAct | empirical | 21988832 |
| TXN | MYC | IntAct | empirical | 21150319 |
| TXN | MYD88 | IntAct | empirical | 21988832 |
| TXN | NCF4 | HPRD, BioGRID | empirical | 10397171 |
| TXN | NFE2 | IntAct | empirical | 21988832 |
| TXN | NFKB1 | HPRD, BioGRID | empirical | 7788295 |
| TXN | PRDX1 | MINT | empirical | 17557078 |
| TXN | UCHL5 | BioGRID | empirical | 21800051 |
| TXN | TMBIM4 | IntAct | empirical | 17353931 |
| TXN | PINX1 | IntAct, BioGRID | empirical | 17353931 |
| TXN | MAPK3 | MINT | empirical | 19935650 |
| TXN | PSPH | IntAct | empirical | 17353931 |
| TXN | SIAH1 | IntAct | empirical | 21988832 |
| TXN | SLC2A4 | IntAct | empirical | 16396496 |
| TXN | DYNLT1 | IntAct | empirical | 21988832 |
| TXN | PRDX2 | MINT | empirical | 17557078 |
| TXN | TP53 | BioGRID | empirical | 19681600 |
| TXN | TRAF6 | IntAct | empirical | 17353931 |
| TXN | TSSC1 | IntAct | empirical | 17353931 |
| TXN | UBC | BioGRID | empirical | 18781797 21139048 21890473 21906983 |
| TXN | VHL | IntAct, BioGRID | empirical | 17353931 |
| TXN | VIM | BioGRID | empirical | 12099690 |
| TXN | YWHAZ | MINT | empirical | 15161933 |
| TXN | FBXO11 | IntAct | empirical | 17353931 |
| TXN | ACTN4 | IntAct | empirical | 21988832 |
| TXN | MAP1LC3B | IntAct | empirical | 20562859 |
| TXN | MAP1LC3A | IntAct | empirical | 20562859 |
| TXN | CD40 | IntAct, BioGRID | empirical | 17353931 |
| TXN | KIAA0101 | BioGRID | empirical | 21628590 |
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
Type 1 Diabetes Publications: 2
-
Overexpression of thioredoxin in islets transduced by a lentiviral vector prolongs graft survival in autoimmune diabetic NOD mice.
Chou FC, Sytwu HK
J Biomed Sci. 2009
PubMed ID: 19671194
-
Molecular scanning of the gene for thioredoxin, an antioxidative and antiapoptotic protein, and genetic susceptibility to type 1 diabetes.
Ikegami H, Ono M, Fujisawa T, Hiromine Y, Kawabata Y, Yamato E
Ann N Y Acad Sci. 2008
PubMed ID: 19120277
Publications: 266
-
The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.
Fang Y, Mu J, Ma Y, Ma D, Fu D, Shen X
Mol Cell Biochem. 2012
PubMed ID: 21800051
-
Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.
Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, Tominaga K, Hubbard GB, Ikeno Y
J Gerontol A Biol Sci Med Sci. 2011
PubMed ID: 21873593
-
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide.
Mikami Y, Shibuya N, Kimura Y, Nagahara N, Ogasawara Y, Kimura H
Biochem J. 2011
PubMed ID: 21732914
-
Activation of extracellular transglutaminase 2 by thioredoxin.
Jin X, Stamnaes J, Klöck C, DiRaimondo TR, Sollid LM, Khosla C
J Biol Chem. 2011
PubMed ID: 21908620
-
Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells.
Farina AR, Cappabianca L, DeSantis G, Di Ianni N, Ruggeri P, Ragone M, Merolle S, Tonissen KF, Gulino A, Mackay AR
FEBS Lett. 2011
PubMed ID: 21963718
-
[Comparison of effects of a single and thrice-repeated moderate hypobaric hypoxia upon expression of thioredoxine-1 in the rat hypothalamus].
Stroev SA, Tiul'kova EI, Samoĭlov MO, Pelto-Hjukko MT
Ross Fiziol Zh Im I M Sechenova. 2011
PubMed ID: 22165200
-
Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells.
Song JS, Cho HH, Lee BJ, Bae YC, Jung JS
Stem Cells Dev. 2011
PubMed ID: 21158569
-
Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability.
Chutkow WA, Lee RT
J Biol Chem. 2011
PubMed ID: 21705327
-
Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor-α: a key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species.
World C, Spindel ON, Berk BC
Arterioscler Thromb Vasc Biol. 2011
PubMed ID: 21636804
-
Axonal protection by 17β-estradiol through thioredoxin-1 in tumor necrosis factor-induced optic neuropathy.
Kitaoka Y, Munemasa Y, Hayashi Y, Kuribayashi J, Koseki N, Kojima K, Kumai T, Ueno S
Endocrinology. 2011
PubMed ID: 21586560
-
Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells.
Yang L, Wu D, Wang X, Cederbaum AI
Free Radic Biol Med. 2011
PubMed ID: 21557999
-
HSP70-mediated control of endothelial cell apoptosis during pre-eclampsia.
Padmini E, Lavanya S
Eur J Obstet Gynecol Reprod Biol. 2011
PubMed ID: 21353370
-
Effects of hyperoxia on cytoplasmic thioredoxin system in alveolar type epithelial cells of premature rats.
Shan R, Chang L, Li W, Liu W, Rong Z, Chen Y, Zeng L
J Huazhong Univ Sci Technolog Med Sci. 2011
PubMed ID: 21505996
-
Thioredoxin increases exocytosis by denitrosylating N-ethylmaleimide-sensitive factor.
Ito T, Yamakuchi M, Lowenstein CJ
J Biol Chem. 2011
PubMed ID: 21324905
-
Neuroprotective mechanisms of minocycline against sphingomyelinase/ceramide toxicity: Roles of Bcl-2 and thioredoxin.
Tang CM, Hwang CS, Chen SD, Yang DI
Free Radic Biol Med. 2011
PubMed ID: 21184825
-
Oxidative stress-induced degradation of thioredoxin-1 and apoptosis is inhibited by thioredoxin-1-actin interaction in endothelial cells.
Zschauer TC, Kunze K, Jakob S, Haendeler J, Altschmied J
Arterioscler Thromb Vasc Biol. 2011
PubMed ID: 21212402
-
Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7.
Yang Y, Ago T, Zhai P, Abdellatif M, Sadoshima J
Circ Res. 2011
PubMed ID: 21183740
-
Biochemical and ultrastructural correlations of calreticulin and thioredoxin expression in breast mucinous carcinoma and infiltrating ductal carcinoma non-special type.
Baltatzis GE, Gaitanarou H, Arnogianaki N, Misitzis J, Voloudakis-Baltatzis IE
Ultrastruct Pathol. 2011
PubMed ID: 20929309
-
Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress.
Mougiakakos D, Johansson CC, Jitschin R, Böttcher M, Kiessling R
Blood. 2011
PubMed ID: 21030559
-
Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy.
Rederstorff M, Castets P, Arbogast S, Lainé J, Vassilopoulos S, Beuvin M, Dubourg O, Vignaud A, Ferry A, Krol A, Allamand V, Guicheney P, Ferreiro A, Lescure A
PLoS One. 2011
PubMed ID: 21858002
-
Increased inflammatory signaling and lethality of influenza H1N1 by nuclear thioredoxin-1.
Go YM, Kang SM, Roede JR, Orr M, Jones DP
PLoS One. 2011
PubMed ID: 21526215
-
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
-
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
-
Thioredoxin 1 enhances neovascularization and reduces ventricular remodeling during chronic myocardial infarction: a study using thioredoxin 1 transgenic mice.
Adluri RS, Thirunavukkarasu M, Zhan L, Akita Y, Samuel SM, Otani H, Ho YS, Maulik G, Maulik N
J Mol Cell Cardiol. 2011
PubMed ID: 21074540
-
Thioredoxin and glutaredoxin system proteins-immunolocalization in the rat central nervous system.
Aon-Bertolino ML, Romero JI, Galeano P, Holubiec M, Badorrey MS, Saraceno GE, Hanschmann EM, Lillig CH, Capani F
Biochim Biophys Acta. 2011
PubMed ID: 20620191
-
Thioredoxin 1 as a subcellular biomarker of redox imbalance in human prostate cancer progression.
Shan W, Zhong W, Zhao R, Oberley TD
Free Radic Biol Med. 2010
PubMed ID: 20955789
-
trans-Resveratrol downregulates Txnip overexpression occurring during liver ischemia-reperfusion.
Nivet-Antoine V, Cottart CH, Lemaréchal H, Vamy M, Margaill I, Beaudeux JL, Bonnefont-Rousselot D, Borderie D
Biochimie. 2010
PubMed ID: 20709139
-
Redox regulation of myocardial ERK 1/2 phosphorylation in experimental hyperthyroidism: role of thioredoxin-peroxiredoxin system.
Araujo AS, Fernandes T, Ribeiro MF, Khaper N, Belló-Klein A
J Cardiovasc Pharmacol. 2010
PubMed ID: 20729758
-
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
-
Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system.
Drechsel DA, Patel M
J Biol Chem. 2010
PubMed ID: 20558743
-
Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Weichsel A, Kem M, Montfort WR
Protein Sci. 2010
PubMed ID: 20662007
-
Structure of human thioredoxin exhibits a large conformational change.
Hall G, Emsley J
Protein Sci. 2010
PubMed ID: 20661909
-
Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets.
Turanov AA, Kehr S, Marino SM, Yoo MH, Carlson BA, Hatfield DL, Gladyshev VN
Biochem J. 2010
PubMed ID: 20536427
-
Transgenic mice overproducing human thioredoxin-1, an antioxidative and anti-apoptotic protein, prevents diabetic embryopathy.
Kamimoto Y, Sugiyama T, Kihira T, Zhang L, Murabayashi N, Umekawa T, Nagao K, Ma N, Toyoda N, Yodoi J, Sagawa N
Diabetologia. 2010
PubMed ID: 20512310
-
Redox regulation of actin by thioredoxin-1 is mediated by the interaction of the proteins via cysteine 62.
Wang X, Ling S, Zhao D, Sun Q, Li Q, Wu F, Nie J, Qu L, Wang B, Shen X, Bai Y, Li Y, Li Y
Antioxid Redox Signal. 2010
PubMed ID: 20218863
-
Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells.
Chen X, Tang W, Liu S, Yu L, Chen Z
Life Sci. 2010
PubMed ID: 20619274
-
Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.
Wang Y, Fu W, Xie F, Wang Y, Chu X, Wang H, Shen M, Wang Y, Wang Y, Sun W, Lei R, Yang L, Wu H, Foo J, Liu J, Jin L, Huang W
J Hum Genet. 2010
PubMed ID: 20485444
-
Japanese encephalitis virus down-regulates thioredoxin and induces ROS-mediated ASK1-ERK/p38 MAPK activation in human promonocyte cells.
Yang TC, Lai CC, Shiu SL, Chuang PH, Tzou BC, Lin YY, Tsai FJ, Lin CW
Microbes Infect. 2010
PubMed ID: 20430109
-
Antioxidant defenses in the rat placenta in late gestation: increased labyrinthine expression of superoxide dismutases, glutathione peroxidase 3, and uncoupling protein 2.
Jones ML, Mark PJ, Lewis JL, Mori TA, Keelan JA, Waddell BJ
Biol Reprod. 2010
PubMed ID: 20393169
-
Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression.
Miniard AC, Middleton LM, Budiman ME, Gerber CA, Driscoll DM
Nucleic Acids Res. 2010
PubMed ID: 20385601
-
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
Im JY, Lee KW, Junn E, Mouradian MM
Neurosci Res. 2010
PubMed ID: 20385180
-
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
-
[The change of thioredoxin system in myocardial tissue of type 2 diabetic rats undergoing myocardial injury].
Zhao XQ, Zhao JJ, Li XY, Zhang Y, Jiao XY
Sheng Li Xue Bao. 2010
PubMed ID: 20571744
-
HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells.
Malec V, Gottschald OR, Li S, Rose F, Seeger W, Hänze J
Free Radic Biol Med. 2010
PubMed ID: 20347035
-
Acute exercise and thioredoxin-1 in rat brain, and alpha-lipoic acid and thioredoxin-interacting protein response, in diabetes.
Lappalainen Z, Lappalainen J, Laaksonen DE, Oksala KJ, Khanna S, Sen CK, Atalay M
Int J Sport Nutr Exerc Metab. 2010
PubMed ID: 20601738
-
Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells.
Hsieh MS, Zhong WB, Yu SC, Lin JY, Chi WM, Lee HM
Circ J. 2010
PubMed ID: 20453393
-
Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice.
Kong L, Zhou X, Li F, Yodoi J, McGinnis J, Cao W
Neurobiol Dis. 2010
PubMed ID: 20298786
-
The roles of thioredoxin and thioredoxin-binding protein-2 in endometriosis.
Seo SK, Yang HI, Lee KE, Kim HY, Cho S, Choi YS, Lee BS
Hum Reprod. 2010
PubMed ID: 20172870
-
Suppression of thioredoxin-1 induces premature senescence in normal human fibroblasts.
Young JJ, Patel A, Rai P
Biochem Biophys Res Commun. 2010
PubMed ID: 20074557
-
PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.
Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, Ogretmen B, Dash R, Sarkar D, Broaddus WC, Grant S, Curiel DT, Fisher PB, Dent P
Cancer Res. 2010
PubMed ID: 20103619
-
Simultaneous expression of glutathione, thioredoxin-1, and their reductases in nerve transected hypoglossal motor neurons of rat.
Hama I, Nakagomi S, Konishi H, Kiyama H
Brain Res. 2010
PubMed ID: 19833109
-
Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PLoS One. 2010
PubMed ID: 20877624
-
Redox responses in patients with sepsis: high correlation of thioredoxin-1 and macrophage migration inhibitory factor plasma levels.
Brenner T, Rosenhagen C, Steppan J, Lichtenstern C, Weitz J, Bruckner T, Martin EO, Hoffmann U, Weigand MA, Hofer S
Mediators Inflamm. 2010
PubMed ID: 20847814
-
Serum C-reactive protein and thioredoxin levels in subjects with mildly reduced glomerular filtration rate.
Tsuchikura S, Shoji T, Shimomura N, Kakiya R, Emoto M, Koyama H, Ishimura E, Inaba M, Nishizawa Y
BMC Nephrol. 2010
PubMed ID: 20423474
-
Thioredoxins 1 and 2 protect retinal ganglion cells from pharmacologically induced oxidative stress, optic nerve transection and ocular hypertension.
Munemasa Y, Kwong JM, Kim SH, Ahn JH, Caprioli J, Piri N
Adv Exp Med Biol. 2010
PubMed ID: 20238036
-
Sex-specific role of thioredoxin in neuroprotection against iron-induced brain injury conferred by estradiol.
Chen TY, Tsai KL, Lee TY, Chiueh CC, Lee WS, Hsu C
Stroke. 2010
PubMed ID: 19940280
-
Expression of thioredoxin during progression of hamster and human cholangiocarcinoma.
Yoon BI, Kim YH, Yi JY, Kang MS, Jang JJ, Joo KH, Kim Y, McHugh Law J, Kim DY
Cancer Sci. 2010
PubMed ID: 19799607
-
Thioredoxin and thioredoxin reductase influence estrogen receptor alpha-mediated gene expression in human breast cancer cells.
Rao AK, Ziegler YS, McLeod IX, Yates JR, Nardulli AM
J Mol Endocrinol. 2009
PubMed ID: 19620238
-
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
-
The cyclin-dependent kinase inhibitor, p21(WAF1), promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells.
Kuljaca S, Liu T, Dwarte T, Kavallaris M, Haber M, Norris MD, Martin-Caballero J, Marshall GM
Carcinogenesis. 2009
PubMed ID: 19773351
-
Alterations of the thioredoxin system by hyperoxia: implications for alveolar development.
Tipple TE, Welty SE, Nelin LD, Hansen JM, Rogers LK
Am J Respir Cell Mol Biol. 2009
PubMed ID: 19244202
-
Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin.
Bernal-Bayard J, Ramos-Morales F
J Biol Chem. 2009
PubMed ID: 19690162
-
Direct association of thioredoxin-1 (TRX) with macrophage migration inhibitory factor (MIF): regulatory role of TRX on MIF internalization and signaling.
Son A, Kato N, Horibe T, Matsuo Y, Mochizuki M, Mitsui A, Kawakami K, Nakamura H, Yodoi J
Antioxid Redox Signal. 2009
PubMed ID: 19601712
-
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin.
Li XN, Song J, Zhang L, LeMaire SA, Hou X, Zhang C, Coselli JS, Chen L, Wang XL, Zhang Y, Shen YH
Diabetes. 2009
PubMed ID: 19592618
-
Effect of thioredoxin deletion and p53 cysteine replacement on human p53 activity in wild-type and thioredoxin reductase null yeast.
Stoner CS, Pearson GD, Koç A, Merwin JR, Lopez NI, Merrill GF
Biochemistry. 2009
PubMed ID: 19681600
-
Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation.
Fernandes AP, Capitanio A, Selenius M, Brodin O, Rundlöf AK, Björnstedt M
Histopathology. 2009
PubMed ID: 19723146
-
The novel oxidative stress marker thioredoxin is increased in first-episode schizophrenic patients.
Zhang XY, Chen da C, Xiu MH, Wang F, Qi LY, Sun HQ, Chen S, He SC, Wu GY, Haile CN, Kosten TA, Lu L, Kosten TR
Schizophr Res. 2009
PubMed ID: 19540723
-
Laser microdissection-based analysis of hypoxia- and thioredoxin-related genes in human stable carotid plaques.
Okami N, Kawamata T, Yamamoto G, Okada Y, Hori T, Tachikawa T
Cardiovasc Pathol. 2009
PubMed ID: 18835792
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
-
Thioredoxin reduces C-C chemokine-induced chemotaxis of human eosinophils.
Kobayashi N, Yamada Y, Ito W, Ueki S, Kayaba H, Nakamura H, Yodoi J, Chihara J
Allergy. 2009
PubMed ID: 19208085
-
High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation.
Luan R, Liu S, Yin T, Lau WB, Wang Q, Guo W, Wang H, Tao L
Cardiovasc Res. 2009
PubMed ID: 19276128
-
Attenuation of neuronal degeneration in thioredoxin-1 overexpressing mice after mild focal ischemia.
Zhou F, Gomi M, Fujimoto M, Hayase M, Marumo T, Masutani H, Yodoi J, Hashimoto N, Nozaki K, Takagi Y
Brain Res. 2009
PubMed ID: 19328186
-
Antioxidative role of selenoprotein W in oxidant-induced mouse embryonic neuronal cell death.
Chung YW, Jeong D, Noh OJ, Park YH, Kang SI, Lee MG, Lee TH, Yim MB, Kim IY
Mol Cells. 2009
PubMed ID: 19466610
-
Thioredoxin 1 delivery as new therapeutics.
Nakamura H, Hoshino Y, Okuyama H, Matsuo Y, Yodoi J
Adv Drug Deliv Rev. 2009
PubMed ID: 19385090
-
[Correlation between thyroid-stimulating hormone-peroxiredoxin1 signaling pathway and invasion of papillary thyroid carcinoma].
Liu X, Gao M
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009
PubMed ID: 19558833
-
Proteomic analysis of human papillomavirus-related oral squamous cell carcinoma: identification of thioredoxin and epidermal-fatty acid binding protein as upregulated protein markers in microdissected tumor tissue.
Melle C, Ernst G, Winkler R, Schimmel B, Klussmann JP, Wittekindt C, Guntinas-Lichius O, von Eggeling F
Proteomics. 2009
PubMed ID: 19337991
-
The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells.
Myers CR, Myers JM
Toxicology. 2009
PubMed ID: 19135121
-
Protective effect of tetraethyl pyrazine against focal cerebral ischemia/reperfusion injury in rats: therapeutic time window and its mechanism.
Jia J, Zhang X, Hu YS, Wu Y, Wang QZ, Li NN, Wu CQ, Yu HX, Guo QC
Thromb Res. 2009
PubMed ID: 19128823
-
Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane.
Kong L, Chen GD, Zhou X, McGinnis JF, Li F, Cao W
Neurochem Int. 2009
PubMed ID: 19114066
-
Diabetes impairs exercise training-associated thioredoxin response and glutathione status in rat brain.
Lappalainen Z, Lappalainen J, Oksala NK, Laaksonen DE, Khanna S, Sen CK, Atalay M
J Appl Physiol. 2009
PubMed ID: 19074570
-
Therapeutic time window and mechanism of tetramethylpyrazine on transient focal cerebral ischemia/reperfusion injury in rats.
Zhu XL, Xiong LZ, Wang Q, Liu ZG, Ma X, Zhu ZH, Hu S, Gong G, Chen SY
Neurosci Lett. 2009
PubMed ID: 18790005
-
Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma.
Cha MK, Suh KH, Kim IH
J Exp Clin Cancer Res. 2009
PubMed ID: 19566940
-
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities.
Lam JB, Chow KH, Xu A, Lam KS, Liu J, Wong NS, Moon RT, Shepherd PR, Cooper GJ, Wang Y
PLoS One. 2009
PubMed ID: 19319191
-
Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
Mavaddat N, Dunning AM, Ponder BA, Easton DF, Pharoah PD
Cancer Epidemiol Biomarkers Prev. 2009
PubMed ID: 19124506
-
Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma.
Munemasa Y, Ahn JH, Kwong JM, Caprioli J, Piri N
Gene Ther. 2009
PubMed ID: 18701913
-
Thioredoxin-1 and its natural inhibitor, vitamin D3 up-regulated protein 1, are differentially regulated by PPARalpha in human macrophages.
Billiet L, Furman C, Cuaz-Pérolin C, Paumelle R, Raymondjean M, Simmet T, Rouis M
J Mol Biol. 2008
PubMed ID: 18848838
-
Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.
Starr JM, Shiels PG, Harris SE, Pattie A, Pearce MS, Relton CL, Deary IJ
Mech Ageing Dev. 2008
PubMed ID: 18977241
-
Thioredoxin in coronary culprit lesions: possible relationship to oxidative stress and intraplaque hemorrhage.
Nishihira K, Yamashita A, Imamura T, Hatakeyama K, Sato Y, Nakamura H, Yodoi J, Ogawa H, Kitamura K, Asada Y
Atherosclerosis. 2008
PubMed ID: 18420212
-
Regulatory role of thioredoxin in homocysteine-induced monocyte chemoattractant protein-1 secretion in monocytes/macrophages.
Dai J, Wang X, Feng J, Kong W, Xu Q, Shen X, Wang X
FEBS Lett. 2008
PubMed ID: 18976655
-
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
-
Lactate stimulates vasculogenic stem cells via the thioredoxin system and engages an autocrine activation loop involving hypoxia-inducible factor 1.
Milovanova TN, Bhopale VM, Sorokina EM, Moore JS, Hunt TK, Hauer-Jensen M, Velazquez OC, Thom SR
Mol Cell Biol. 2008
PubMed ID: 18710947
-
Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residues.
Hashemy SI, Holmgren A
J Biol Chem. 2008
PubMed ID: 18544525
-
Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression.
Fortin JS, Côté MF, Lacroix J, Petitclerc E, C-Gaudreault R
Bioorg Med Chem. 2008
PubMed ID: 18579387
-
Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism.
Umekawa T, Sugiyama T, Kihira T, Murabayashi N, Zhang L, Nagao K, Kamimoto Y, Ma N, Yodoi J, Sagawa N
Endocrinology. 2008
PubMed ID: 18450962
-
Oxidation and nuclear localization of thioredoxin-1 in sparse cell cultures.
Spielberger JC, Moody AD, Watson WH
J Cell Biochem. 2008
PubMed ID: 18384140
-
A mitochondrial protein compendium elucidates complex I disease biology.
Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, Mootha VK
Cell. 2008
PubMed ID: 18614015
-
Severe liver steatosis correlates with nitrosative and oxidative stress in rats.
Grattagliano I, Caraceni P, Calamita G, Ferri D, Gargano I, Palasciano G, Portincasa P
Eur J Clin Invest. 2008
PubMed ID: 18578693
-
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy.
Ago T, Liu T, Zhai P, Chen W, Li H, Molkentin JD, Vatner SF, Sadoshima J
Cell. 2008
PubMed ID: 18555775
-
Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins.
Benhar M, Forrester MT, Hess DT, Stamler JS
Science. 2008
PubMed ID: 18497292
-
Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer.
Noike T, Miwa S, Soeda J, Kobayashi A, Miyagawa S
Hum Pathol. 2008
PubMed ID: 17949784
-
Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production.
Kim SH, Oh J, Choi JY, Jang JY, Kang MW, Lee CE
BMC Immunol. 2008
PubMed ID: 18983687
-
Induction of IFN-gamma gene expression by thioredoxin: positive feed-back regulation of Th1 response by thioredoxin and IFN-gamma.
Kang MW, Jang JY, Choi JY, Kim SH, Oh J, Cho BS, Lee CE
Cell Physiol Biochem. 2008
PubMed ID: 18209488
-
Redox regulation of resveratrol-mediated switching of death signal into survival signal.
Das S, Khan N, Mukherjee S, Bagchi D, Gurusamy N, Swartz H, Das DK
Free Radic Biol Med. 2008
PubMed ID: 18045550
-
Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1.
Fujino G, Noguchi T, Matsuzawa A, Yamauchi S, Saitoh M, Takeda K, Ichijo H
Mol Cell Biol. 2007
PubMed ID: 17724081
-
Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion.
Go YM, Halvey PJ, Hansen JM, Reed M, Pohl J, Jones DP
Am J Pathol. 2007
PubMed ID: 17982132
-
Probing the chemistry of thioredoxin catalysis with force.
Wiita AP, Perez-Jimenez R, Walther KA, Gräter F, Berne BJ, Holmgren A, Sanchez-Ruiz JM, Fernandez JM
Nature. 2007
PubMed ID: 17972886
-
Nuclear redox-signaling is essential for apoptosis inhibition in endothelial cells--important role for nuclear thioredoxin-1.
Schroeder P, Popp R, Wiegand B, Altschmied J, Haendeler J
Arterioscler Thromb Vasc Biol. 2007
PubMed ID: 17823364
-
Thioredoxin may exert a protective effect against tissue damage caused by oxidative stress in salivary glands of patients with Sjögren's syndrome.
Kurimoto C, Kawano S, Tsuji G, Hatachi S, Jikimoto T, Sugiyama D, Kasagi S, Komori T, Nakamura H, Yodoi J, Kumagai S
J Rheumatol. 2007
PubMed ID: 17896802
-
Disulfide Bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2)O(2)-induced c-Jun NH(2)-terminal kinase activation and apoptosis.
Nadeau PJ, Charette SJ, Toledano MB, Landry J
Mol Biol Cell. 2007
PubMed ID: 17652454
-
Nuclear thioredoxin-1 is required to suppress cisplatin-mediated apoptosis of MCF-7 cells.
Chen XP, Liu S, Tang WX, Chen ZW
Biochem Biophys Res Commun. 2007
PubMed ID: 17651689
-
Expression of genes for thioredoxin 1 and thioredoxin 2 in multidrug resistance ovarian carcinoma cells SKVLB.
Kalinina EV, Chernov NN, Saprin AN, Kotova YN, Gavrilova YA, Chermnykh NS, Shcherbak NP
Bull Exp Biol Med. 2007
PubMed ID: 18457020
-
EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W
Brief Funct Genomic Proteomic. 2007
PubMed ID: 17967808
-
Genetic analysis of hyperoxic acute lung injury survival in reciprocal intercross mice.
Prows DR, Hafertepen AP, Winterberg AV, Gibbons WJ, Liu C, Nick TG
Physiol Genomics. 2007
PubMed ID: 17488888
-
Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer.
Udler M, Maia AT, Cebrian A, Brown C, Greenberg D, Shah M, Caldas C, Dunning A, Easton D, Ponder B, Pharoah P
J Clin Oncol. 2007
PubMed ID: 17634480
-
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1.
Schwertassek U, Balmer Y, Gutscher M, Weingarten L, Preuss M, Engelhard J, Winkler M, Dick TP
EMBO J. 2007
PubMed ID: 17557078
-
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.
Mitchell DA, Morton SU, Fernhoff NB, Marletta MA
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17606900
-
Pressure effects on the structure and function of human thioredoxin.
Ado K, Taniguchi Y
Biochim Biophys Acta. 2007
PubMed ID: 17574940
-
Basal and angiotensin II-inhibited neuronal delayed-rectifier K+ current are regulated by thioredoxin.
Matsuura T, Harrison RA, Westwell AD, Nakamura H, Martynyuk AE, Sumners C
Am J Physiol Cell Physiol. 2007
PubMed ID: 17360810
-
Overexpression of thioredoxin1 in transgenic mice suppresses development of diabetic nephropathy.
Hamada Y, Miyata S, Nii-Kono T, Kitazawa R, Kitazawa S, Higo S, Fukunaga M, Ueyama S, Nakamura H, Yodoi J, Fukagawa M, Kasuga M
Nephrol Dial Transplant. 2007
PubMed ID: 17360766
-
Regulation of the activity of the tumor suppressor PTEN by thioredoxin in Drosophila melanogaster.
Song Z, Saghafi N, Gokhale V, Brabant M, Meuillet EJ
Exp Cell Res. 2007
PubMed ID: 17316609
-
Dissection of complex protein dynamics in human thioredoxin.
Qiu W, Wang L, Lu W, Boechler A, Sanders DA, Zhong D
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17369362
-
Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha.
Zhou J, Damdimopoulos AE, Spyrou G, Brüne B
J Biol Chem. 2007
PubMed ID: 17220299
-
Buried S-nitrosocysteine revealed in crystal structures of human thioredoxin.
Weichsel A, Brailey JL, Montfort WR
Biochemistry. 2007
PubMed ID: 17260951
-
Mutual changes of thioredoxin and nitrosothiols during biliary cirrhosis: results from humans and cholestatic rats.
Grattagliano I, Portincasa P, Palmieri VO, Palasciano G
Hepatology. 2007
PubMed ID: 17256724
-
Thioredoxin-dependent enzymatic activation of mercaptopyruvate sulfurtransferase. An intersubunit disulfide bond serves as a redox switch for activation.
Nagahara N, Yoshii T, Abe Y, Matsumura T
J Biol Chem. 2007
PubMed ID: 17130129
-
Stable expression of a novel fusion peptide of thioredoxin-1 and ABAD-inhibiting peptide protects PC12 cells from intracellular amyloid-beta.
Yang X, Yang Y, Wu J, Zhu J
J Mol Neurosci. 2007
PubMed ID: 17917077
-
A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
Harris SE, Fox H, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ
BMC Genet. 2007
PubMed ID: 17601350
-
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
-
Contribution of thioredoxin reductase to T-cell mitogenesis and NF-kappaB DNA-binding promoted by selenite.
Ueno H, Kajihara H, Nakamura H, Yodoi J, Nakamuro K
Antioxid Redox Signal. 2007
PubMed ID: 17115890
-
Thioredoxin-1 protects against hyperoxia-induced apoptosis in cells of the alveolar walls.
Yamada T, Iwasaki Y, Nagata K, Fushiki S, Nakamura H, Marunaka Y, Yodoi J
Pulm Pharmacol Ther. 2007
PubMed ID: 17045827
-
Mitochondrial thioredoxin in regulation of oxidant-induced cell death.
Chen Y, Cai J, Jones DP
FEBS Lett. 2006
PubMed ID: 17113580
-
Thioredoxin overexpression in mice, model of attenuation of oxidative stress, prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.
Li GX, Hirabayashi Y, Yoon BI, Kawasaki Y, Tsuboi I, Kodama Y, Kurokawa Y, Yodoi J, Kanno J, Inoue T
Exp Hematol. 2006
PubMed ID: 17157166
-
Nitric oxide-dependent suppression of thioredoxin-interacting protein expression enhances thioredoxin activity.
Schulze PC, Liu H, Choe E, Yoshioka J, Shalev A, Bloch KD, Lee RT
Arterioscler Thromb Vasc Biol. 2006
PubMed ID: 17023680
-
Thioredoxin and ventricular remodeling.
Ago T, Sadoshima J
J Mol Cell Cardiol. 2006
PubMed ID: 17007870
-
Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis.
Tao L, Jiao X, Gao E, Lau WB, Yuan Y, Lopez B, Christopher T, RamachandraRao SP, Williams W, Southan G, Sharma K, Koch W, Ma XL
Circulation. 2006
PubMed ID: 16966583
-
Thioredoxin-1 suppresses systemic inflammatory responses against cigarette smoking.
Sato A, Hara T, Nakamura H, Kato N, Hoshino Y, Kondo N, Mishima M, Yodoi J
Antioxid Redox Signal. 2006
PubMed ID: 16987041
-
Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice.
Ohashi S, Nishio A, Nakamura H, Asada M, Tamaki H, Kawasaki K, Fukui T, Yodoi J, Chiba T
Antioxid Redox Signal. 2006
PubMed ID: 16987036
-
Thioredoxin1 upregulates mitochondrial proteins related to oxidative phosphorylation and TCA cycle in the heart.
Ago T, Yeh I, Yamamoto M, Schinke-Braun M, Brown JA, Tian B, Sadoshima J
Antioxid Redox Signal. 2006
PubMed ID: 16987018
-
The tert-butylhydroquinone-mediated activation of the human thioredoxin gene reveals a novel promoter structure.
Osborne SA, Hawkes HJ, Baldwin BL, Alexander KA, Svingen T, Clarke FM, Tonissen KF
Biochem J. 2006
PubMed ID: 16712525
-
Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease.
Akterin S, Cowburn RF, Miranda-Vizuete A, Jiménez A, Bogdanovic N, Winblad B, Cedazo-Minguez A
Cell Death Differ. 2006
PubMed ID: 16311508
-
Interactions between genes involved in the antioxidant defence system and breast cancer risk.
Oestergaard MZ, Tyrer J, Cebrian A, Shah M, Dunning AM, Ponder BA, Easton DF, Pharoah PD
Br J Cancer. 2006
PubMed ID: 16868544
-
The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.
Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, Lee RT
J Biol Chem. 2006
PubMed ID: 16766796
-
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y
Mol Cell. 2006
PubMed ID: 16916647
-
Role of protein disulfide isomerase and other thiol-reactive proteins in HIV-1 envelope protein-mediated fusion.
Ou W, Silver J
Virology. 2006
PubMed ID: 16507315
-
Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity.
Urig S, Lieske J, Fritz-Wolf K, Irmler A, Becker K
FEBS Lett. 2006
PubMed ID: 16750198
-
Thioredoxin protects against joint destruction in a murine arthritis model.
Tsuji G, Koshiba M, Nakamura H, Kosaka H, Hatachi S, Kurimoto C, Kurosaka M, Hayashi Y, Yodoi J, Kumagai S
Free Radic Biol Med. 2006
PubMed ID: 16678011
-
Thioredoxin-mediated negative autoregulation of peroxisome proliferator-activated receptor alpha transcriptional activity.
Liu GH, Qu J, Shen X
Mol Biol Cell. 2006
PubMed ID: 16492688
-
Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis.
Ohashi S, Nishio A, Nakamura H, Kido M, Ueno S, Uza N, Inoue S, Kitamura H, Kiriya K, Asada M, Tamaki H, Matsuura M, Kawasaki K, Fukui T, Watanabe N, Nakase H, Yodoi J, Okazaki K, Chiba T
Am J Physiol Gastrointest Liver Physiol. 2006
PubMed ID: 16322089
-
Redox-regulated cochaperone activity of the human DnaJ homolog Hdj2.
Choi HI, Lee SP, Kim KS, Hwang CY, Lee YR, Chae SK, Kim YS, Chae HZ, Kwon KS
Free Radic Biol Med. 2006
PubMed ID: 16458196
-
Redox regulation of mast cell histamine release in thioredoxin-1 (TRX) transgenic mice.
Son A, Nakamura H, Kondo N, Matsuo Y, Liu W, Oka S, Ishii Y, Yodoi J
Cell Res. 2006
PubMed ID: 16474438
-
Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice.
Hsieh CC, Papaconstantinou J
FASEB J. 2006
PubMed ID: 16449798
-
Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer.
Cebrian A, Pharoah PD, Ahmed S, Smith PL, Luccarini C, Luben R, Redman K, Munday H, Easton DF, Dunning AM, Ponder BA
Cancer Res. 2006
PubMed ID: 16424062
-
Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis.
Haendeler J, Popp R, Goy C, Tischler V, Zeiher AM, Dimmeler S
J Biol Chem. 2005
PubMed ID: 16263712
-
Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages.
Billiet L, Furman C, Larigauderie G, Copin C, Brand K, Fruchart JC, Rouis M
J Biol Chem. 2005
PubMed ID: 16207716
-
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
-
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
-
Requirements for the different cysteines in the chemotactic and desensitizing activity of human thioredoxin.
Bizzarri C, Holmgren A, Pekkari K, Chang G, Colotta F, Ghezzi P, Bertini R
Antioxid Redox Signal. 2005
PubMed ID: 16115022
-
Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.
Gevaert K, Staes A, Van Damme J, De Groot S, Hugelier K, Demol H, Martens L, Goethals M, Vandekerckhove J
Proteomics. 2005
PubMed ID: 16097034
-
Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.
Kawasaki K, Nishio A, Nakamura H, Uchida K, Fukui T, Ohana M, Yoshizawa H, Ohashi S, Tamaki H, Matsuura M, Asada M, Nishi T, Nakase H, Toyokuni S, Liu W, Yodoi J, Okazaki K, Chiba T
Lab Invest. 2005
PubMed ID: 15965489
-
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine.
Mitchell DA, Marletta MA
Nat Chem Biol. 2005
PubMed ID: 16408020
-
Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB.
Li Y, Liu W, Xing G, Tian C, Zhu Y, He F
Cell Signal. 2005
PubMed ID: 15894171
-
Roles of thioredoxin reductase 1 and APE/Ref-1 in the control of basal p53 stability and activity.
Seemann S, Hainaut P
Oncogene. 2005
PubMed ID: 15824742
-
Plasma thioredoxin levels in patients with unstable angina.
Hokamaki J, Kawano H, Soejima H, Miyamoto S, Kajiwara I, Kojima S, Sakamoto T, Sugiyama S, Yoshimura M, Nakamura H, Yodoi J, Ogawa H
Int J Cardiol. 2005
PubMed ID: 15749180
-
Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras.
Kuster GM, Pimentel DR, Adachi T, Ido Y, Brenner DA, Cohen RA, Liao R, Siwik DA, Colucci WS
Circulation. 2005
PubMed ID: 15723974
-
Elevated thioredoxin after angioplasty in peripheral arterial disease.
Wahlgren CM, Pekkari K
Eur J Vasc Endovasc Surg. 2005
PubMed ID: 15694802
-
PSK and Trx80 inhibit B-cell growth in EBV-infected cord blood mononuclear cells through T cells activated by the monocyte products IL-15 and IL-12.
Liu A, Arbiser JL, Holmgren A, Klein G, Klein E
Blood. 2005
PubMed ID: 15507528
-
Truncated thioredoxin (Trx80) induces differentiation of human CD14+ monocytes into a novel cell type (TAMs) via activation of the MAP kinases p38, ERK, and JNK.
Pekkari K, Goodarzi MT, Scheynius A, Holmgren A, Avila-Cariño J
Blood. 2005
PubMed ID: 15494431
-
Effects of dietary selenium on post-ischemic expression of antioxidant mRNA.
Venardos K, Ashton K, Headrick J, Perkins A
Mol Cell Biochem. 2005
PubMed ID: 15792362
-
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1.
Hwang CY, Ryu YS, Chung MS, Kim KD, Park SS, Chae SK, Chae HZ, Kwon KS
Oncogene. 2004
PubMed ID: 15480426
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
-
Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase.
Meng Y, Takahashi H, Meng J, Zhang Y, Lu G, Asrar S, Nakamura T, Jia Z
Neuropharmacology. 2004
PubMed ID: 15458846
-
Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity.
Meuillet EJ, Mahadevan D, Berggren M, Coon A, Powis G
Arch Biochem Biophys. 2004
PubMed ID: 15313215
-
Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1.
Nishinaka Y, Masutani H, Oka S, Matsuo Y, Yamaguchi Y, Nishio K, Ishii Y, Yodoi J
J Biol Chem. 2004
PubMed ID: 15234975
-
S-nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1.
Yasinska IM, Kozhukhar AV, Sumbayev VV
Arch Biochem Biophys. 2004
PubMed ID: 15246877
-
Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein.
Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT
J Biol Chem. 2004
PubMed ID: 15128745
-
Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity.
Yoshioka J, Schulze PC, Cupesi M, Sylvan JD, MacGillivray C, Gannon J, Huang H, Lee RT
Circulation. 2004
PubMed ID: 15123525
-
DNA sequence and analysis of human chromosome 9.
Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H, Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y, Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW, Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA, French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JG, Glison C, Grafham DV, Gribble S, Griffiths C, Griffiths-Jones S, Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ES, Hart EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ, Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J, Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE, McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV, Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S, Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L, Ashurst JL, Coulson A, Blöcker H, Durbin R, Sulston JE, Hubbard T, Jackson MJ, Bentley DR, Beck S, Rogers J, Dunham I
Nature. 2004
PubMed ID: 15164053
-
Oxidant-injured airway epithelial cells upregulate thioredoxin but do not produce interleukin-8.
Oslund KL, Miller LA, Usachenko JL, Tyler NK, Wu R, Hyde DM
Am J Respir Cell Mol Biol. 2004
PubMed ID: 15096327
-
Thioredoxin liquefies and decreases the viscoelasticity of cystic fibrosis sputum.
Rancourt RC, Tai S, King M, Heltshe SL, Penvari C, Accurso FJ, White CW
Am J Physiol Lung Cell Mol Physiol. 2004
PubMed ID: 14695120
-
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome Res. 2004
PubMed ID: 15060019
-
Thioredoxin, a regulator of gene expression.
Kontou M, Will RD, Adelfalk C, Wittig R, Poustka A, Hirsch-Kauffmann M, Schweiger M
Oncogene. 2004
PubMed ID: 14730345
-
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
-
Redox-sensing release of human thioredoxin from T lymphocytes with negative feedback loops.
Kondo N, Ishii Y, Kwon YW, Tanito M, Horita H, Nishinaka Y, Nakamura H, Yodoi J
J Immunol. 2004
PubMed ID: 14688353
-
Thioredoxin inhibits microvascular endothelial capillary tubule formation.
Farina AR, Tacconelli A, Cappabianca L, DeSantis G, Gulino A, Mackay AR
Exp Cell Res. 2003
PubMed ID: 14644168
-
Increased plasma thioredoxin in patients with acute myocardial infarction.
Soejima H, Suefuji H, Miyamoto S, Kajiwaram I, Kojima S, Hokamaki J, Sakamoto T, Yoshimura M, Nakamura H, Yodoi J, Ogawa H
Clin Cardiol. 2003
PubMed ID: 14677813
-
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell. 2003
PubMed ID: 14651853
-
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
-
Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa.
Khomenko T, Deng X, Jadus MR, Szabo S
Biochem Biophys Res Commun. 2003
PubMed ID: 13679060
-
Preferential elevation of Prx I and Trx expression in lung cancer cells following hypoxia and in human lung cancer tissues.
Kim HJ, Chae HZ, Kim YJ, Kim YH, Hwangs TS, Park EM, Park YM
Cell Biol Toxicol. 2003
PubMed ID: 14703116
-
Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif.
Watson WH, Pohl J, Montfort WR, Stuchlik O, Reed MS, Powis G, Jones DP
J Biol Chem. 2003
PubMed ID: 12816947
-
Immunohistochemical determination of thioredoxin and glutaredoxin distribution in the human cervix, and possible relation to cervical ripening.
Lysell J, Stjernholm Vladic Y, Ciarlo N, Holmgren A, Sahlin L
Gynecol Endocrinol. 2003
PubMed ID: 14503974
-
Human lens thioredoxin: molecular cloning and functional characterization.
Yegorova S, Liu A, Lou MF
Invest Ophthalmol Vis Sci. 2003
PubMed ID: 12882768
-
Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival.
Raffel J, Bhattacharyya AK, Gallegos A, Cui H, Einspahr JG, Alberts DS, Powis G
J Lab Clin Med. 2003
PubMed ID: 12878985
-
Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells.
Husbeck B, Stringer DE, Gerner EW, Powis G
Biochem Biophys Res Commun. 2003
PubMed ID: 12804587
-
Upregulation of redox-regulating protein, thioredoxin, in endomyocardial biopsy samples of patients with myocarditis and cardiomyopathies.
Nimata M, Kishimoto C, Shioji K, Ishizaki K, Kitaguchi S, Hashimoto T, Nagata N, Kawai C
Mol Cell Biochem. 2003
PubMed ID: 12870673
-
Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice.
Okuyama H, Nakamura H, Shimahara Y, Araya S, Kawada N, Yamaoka Y, Yodoi J
Hepatology. 2003
PubMed ID: 12717382
-
The nonclassic secretion of thioredoxin is not sensitive to redox state.
Tanudji M, Hevi S, Chuck SL
Am J Physiol Cell Physiol. 2003
PubMed ID: 12529245
-
Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response.
Kim YC, Yamaguchi Y, Kondo N, Masutani H, Yodoi J
Oncogene. 2003
PubMed ID: 12660821
-
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
-
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
-
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
-
Role of glutaredoxin in metabolic oxidative stress. Glutaredoxin as a sensor of oxidative stress mediated by H2O2.
Song JJ, Rhee JG, Suntharalingam M, Walsh SA, Spitz DR, Lee YJ
J Biol Chem. 2002
PubMed ID: 12244106
-
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.
Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S
Nat Cell Biol. 2002
PubMed ID: 12244325
-
The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.
Butler LM, Zhou X, Xu WS, Scher HI, Rifkind RA, Marks PA, Richon VM
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12189205
-
Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems.
Casagrande S, Bonetto V, Fratelli M, Gianazza E, Eberini I, Massignan T, Salmona M, Chang G, Holmgren A, Ghezzi P
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12119401
-
C-propeptide region of human pro alpha 1 type 1 collagen interacts with thioredoxin.
Matsumoto K, Masutani H, Nishiyama A, Hashimoto S, Gon Y, Horie T, Yodoi J
Biochem Biophys Res Commun. 2002
PubMed ID: 12099690
-
Vitamin D(3)-up-regulated protein-1 is a stress-responsive gene that regulates cardiomyocyte viability through interaction with thioredoxin.
Wang Y, De Keulenaer GW, Lee RT
J Biol Chem. 2002
PubMed ID: 12011048
-
Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner.
Liu Y, Min W
Circ Res. 2002
PubMed ID: 12089063
-
Enhanced resistancy of thioredoxin-transgenic mice against influenza virus-induced pneumonia.
Nakamura H, Tamura S, Watanabe I, Iwasaki T, Yodoi J
Immunol Lett. 2002
PubMed ID: 12008049
-
Immunohistochemical localization of glutaredoxin and thioredoxin in human endometrium: a possible association with pinopodes.
Stavréus-Evers A, Masironi B, Landgren BM, Holmgren A, Eriksson H, Sahlin L
Mol Hum Reprod. 2002
PubMed ID: 12029072
-
Crystal structure of the catalytic domain of a human thioredoxin-like protein.
Jin J, Chen X, Zhou Y, Bartlam M, Guo Q, Liu Y, Sun Y, Gao Y, Ye S, Li G, Rao Z, Qiang B, Yuan J
Eur J Biochem. 2002
PubMed ID: 11985582
-
The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells.
Andoh T, Chock PB, Chiueh CC
J Biol Chem. 2002
PubMed ID: 11751890
-
Elevation of serum thioredoxin levels in patients with type 2 diabetes.
Kakisaka Y, Nakashima T, Sumida Y, Yoh T, Nakamura H, Yodoi J, Senmaru H
Horm Metab Res. 2002
PubMed ID: 11972307
-
Intracellular thiol redox status of macrophages directs the Th1 skewing in thioredoxin transgenic mice during aging.
Murata Y, Amao M, Yoneda J, Hamuro J
Mol Immunol. 2002
PubMed ID: 11841834
-
Thioredoxin-mediated redox control of human T cell lymphotropic virus type I (HTLV-I) gene expression.
Sasada T, Nakamura H, Masutani H, Ueda S, Sono H, Takabayashi A, Yodoi J
Mol Immunol. 2002
PubMed ID: 11841832
-
Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.
Guittet O, Håkansson P, Voevodskaya N, Fridd S, Gräslund A, Arakawa H, Nakamura Y, Thelander L
J Biol Chem. 2001
PubMed ID: 11517226
-
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.
Morita K, Saitoh M, Tobiume K, Matsuura H, Enomoto S, Nishitoh H, Ichijo H
EMBO J. 2001
PubMed ID: 11689443
-
HIV-1 Nef: negative effector of Fas?
Xu XN, Screaton G
Nat Immunol. 2001
PubMed ID: 11323689
-
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.
Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC
Nature. 2001
PubMed ID: 11298454
-
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
-
Regulatory roles of thioredoxin in oxidative stress-induced cellular responses.
Nishinaka Y, Masutani H, Nakamura H, Yodoi J
Redox Rep. 2001
PubMed ID: 11778846
-
Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study.
Kobayashi M, Nakamura H, Yodoi J, Shiota K
Ital J Anat Embryol. 2001
PubMed ID: 11732570
-
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation.
Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, Laszlo A, Spitz DR, Goswami PC, Yodoi J, Gius D
Cancer Res. 2000
PubMed ID: 11118054
-
Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma.
Pekkari K, Gurunath R, Arner ES, Holmgren A
J Biol Chem. 2000
PubMed ID: 10982790
-
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
-
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
-
Physiological functions of thioredoxin and thioredoxin reductase.
Arnér ES, Holmgren A
Eur J Biochem. 2000
PubMed ID: 11012661
-
Trafficking of neutrophils across airway epithelium is dependent upon both thioredoxin- and pertussis toxin-sensitive signaling mechanisms.
Miller LA, Usachenko J, McDonald RJ, Hyde DM
J Leukoc Biol. 2000
PubMed ID: 10947064
-
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
-
Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function.
Junn E, Han SH, Im JY, Yang Y, Cho EW, Um HD, Kim DK, Lee KW, Han PL, Rhee SG, Choi I
J Immunol. 2000
PubMed ID: 10843682
-
A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system.
Yamanaka H, Maehira F, Oshiro M, Asato T, Yanagawa Y, Takei H, Nakashima Y
Biochem Biophys Res Commun. 2000
PubMed ID: 10814541
-
Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses.
Kobayashi M, Nakamura H, Yodoi J, Shiota K
Antioxid Redox Signal. 2000
PubMed ID: 11213470
-
Thioredoxin-dependent redox regulation of p53-mediated p21 activation.
Ueno M, Masutani H, Arai RJ, Yamauchi A, Hirota K, Sakai T, Inamoto T, Yamaoka Y, Yodoi J, Nikaido T
J Biol Chem. 1999
PubMed ID: 10585464
-
Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression.
Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, Yodoi J
J Biol Chem. 1999
PubMed ID: 10419473
-
Demonstration of the interaction of thioredoxin with p40phox, a phagocyte oxidase component, using a yeast two-hybrid system.
Nishiyama A, Ohno T, Iwata S, Matsui M, Hirota K, Masutani H, Nakamura H, Yodoi J
Immunol Lett. 1999
PubMed ID: 10397171
-
Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function.
Makino Y, Yoshikawa N, Okamoto K, Hirota K, Yodoi J, Makino I, Tanaka H
J Biol Chem. 1999
PubMed ID: 9915858
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
-
Expression of thioredoxin is enhanced in atherosclerotic plaques and during neointima formation in rat arteries.
Takagi Y, Gon Y, Todaka T, Nozaki K, Nishiyama A, Sono H, Hashimoto N, Kikuchi H, Yodoi J
Lab Invest. 1998
PubMed ID: 9714183
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H
EMBO J. 1998
PubMed ID: 9564042
-
The expression of thioredoxin mRNA is increased in the human cervix during pregnancy.
Sahlin L, Stjernholm Y, Holmgren A, Ekman G, Eriksson H
Mol Hum Reprod. 1997
PubMed ID: 9464857
-
Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
Andersen JF, Sanders DA, Gasdaska JR, Weichsel A, Powis G, Montfort WR
Biochemistry. 1997
PubMed ID: 9369469
-
Thioredoxin expression in the human endometrium during the menstrual cycle.
Maruyama T, Kitaoka Y, Sachi Y, Nakanoin K, Hirota K, Shiozawa T, Yoshimura Y, Fujii S, Yodoi J
Mol Hum Reprod. 1997
PubMed ID: 9433926
-
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1.
Hirota K, Matsui M, Iwata S, Nishiyama A, Mori K, Yodoi J
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9108029
-
A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells.
Garrett-Sinha LA, Eberspaecher H, Seldin MF, de Crombrugghe B
J Biol Chem. 1996
PubMed ID: 8940147
-
Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene.
Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J, Taketo MM
Dev Biol. 1996
PubMed ID: 8812119
-
Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Weichsel A, Gasdaska JR, Powis G, Montfort WR
Structure. 1996
PubMed ID: 8805557
-
The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Qin J, Clore GM, Kennedy WP, Kuszewski J, Gronenborn AM
Structure. 1996
PubMed ID: 8736558
-
Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts.
Guthridge MA, Seldin M, Basilico C
Oncogene. 1996
PubMed ID: 8649829
-
Thioredoxin, a mediator of growth inhibition, maps to 9q31.
Heppell-Parton A, Cahn A, Bench A, Lowe N, Lehrach H, Zehetner G, Rabbitts P
Genomics. 1995
PubMed ID: 7601465
-
Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Qin J, Clore GM, Kennedy WM, Huth JR, Gronenborn AM
Structure. 1995
PubMed ID: 7788295
-
Structure of the mouse thioredoxin-encoding gene and its processed pseudogene.
Matsui M, Taniguchi Y, Hirota K, Taketo M, Yodoi J
Gene. 1995
PubMed ID: 7835695
-
Construction of a human full-length cDNA bank.
Kato S, Sekine S, Oh SW, Kim NS, Umezawa Y, Abe N, Yokoyama-Kobayashi M, Aoki T
Gene. 1994
PubMed ID: 7821789
-
Characterization of a thioredoxin-related surface protein.
Dean MF, Martin H, Sansom PA
Biochem J. 1994
PubMed ID: 7818492
-
The predicted amino acid sequence of human thioredoxin is identical to that of the autocrine growth factor human adult T-cell derived factor (ADF): thioredoxin mRNA is elevated in some human tumors.
Gasdaska PY, Oblong JE, Cotgreave IA, Powis G
Biochim Biophys Acta. 1994
PubMed ID: 8049254
-
The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Qin J, Clore GM, Gronenborn AM
Structure. 1994
PubMed ID: 7922028
-
ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction.
Tagaya Y, Maeda Y, Mitsui A, Kondo N, Matsui H, Hamuro J, Brown N, Arai K, Yokota T, Wakasugi H
EMBO J. 1994
PubMed ID: 8187776
-
Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1.
Taketo M, Matsui M, Rochelle JM, Yodoi J, Seldin MF
Genomics. 1994
PubMed ID: 8088797
-
Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway.
Rubartelli A, Bajetto A, Allavena G, Wollman E, Sitia R
J Biol Chem. 1992
PubMed ID: 1332947
-
Isolation and characterization of human thioredoxin-encoding genes.
Tonissen KF, Wells JR
Gene. 1991
PubMed ID: 1874447
-
High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Forman-Kay JD, Clore GM, Wingfield PT, Gronenborn AM
Biochemistry. 1991
PubMed ID: 2001356
-
Identification of a thioredoxin-related protein associated with plasma membranes.
Martin H, Dean M
Biochem Biophys Res Commun. 1991
PubMed ID: 1998498
-
Human thioredoxin reactivity-structure/function relationship.
Jacquot JP, de Lamotte F, Fontecave M, Schürmann P, Decottignies P, Miginiac-Maslow M, Wollman E
Biochem Biophys Res Commun. 1990
PubMed ID: 2176490
-
A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin.
Forman-Kay JD, Clore GM, Driscoll PC, Wingfield P, Richards FM, Gronenborn AM
Biochemistry. 1989
PubMed ID: 2684271
-
Nucleotide sequence of a cDNA encoding rat thioredoxin.
Tonissen KF, Robins AJ, Wells JR
Nucleic Acids Res. 1989
PubMed ID: 2734107
-
ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction.
Tagaya Y, Maeda Y, Mitsui A, Kondo N, Matsui H, Hamuro J, Brown N, Arai K, Yokota T, Wakasugi H
EMBO J. 1989
PubMed ID: 2785919
-
Cloning and expression of a cDNA for human thioredoxin.
Wollman EE, d'Auriol L, Rimsky L, Shaw A, Jacquot JP, Wingfield P, Graber P, Dessarps F, Robin P, Galibert F
J Biol Chem. 1988
PubMed ID: 3170595
Model Organism Phenotype Links
|
Relevant resources: