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CCR2

Gene Description:   chemokine (C-C motif) receptor 2 Synonyms:   Cc-ckr-2, MGC103828, CC-CKR-2, MGC168006, CCR2A, Ccr2a, mJe-r, CKR2, Ccr2b, Ckr2, FLJ78302, CKR2A, MGC111760, MCP-1-R, Cmkbr2, Ckr2a, CCR2B, Ckr2b, CCR2, CMKBR2, CD192, Ccr2, CKR2B Orthologs:   Human CCR2 (protein-coding), Mouse Ccr2 (protein-coding), Rat Ccr2 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, KEGG Human-Rat: HomoloGene, MGD, RGD, OrthoMCL, KEGG Mouse-Rat: HomoloGene, MGD, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1 Rat: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
3p21.31	Human	chr3:45980673..46654132	0.67	77	rs333 rs11711054

Other Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Human 3p21.31 Orthologous Region	Mouse	chr9:123713859..124045161	0.33	9
Human 3p21.31 Orthologous Region	Rat	chr8:128563968..128916583	0.35	8

(Human) GRCh37 - chr3:46395225..46402419 (7.19 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr9:124016689..124028296 (11.61 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr8:128892784..128893905 (1.12 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas no data no data no data no data no data

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for CCR2: The CCR2 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs CCR2   CCL16   Reactome  predicted  7679328  8048929  9207005

View all

KEGG Network: 2   Chemokine signaling pathway Human - 4062 Mouse - 4062 Rat - 4062 Cytokine-cytokine receptor interaction Human - 4060 Mouse - 4060 Rat - 4060

Biocarta: 1   Selective expression of chemokine receptors during T-cell polarization Mouse

Reactome: 7   Chemokine receptors bind chemokines REACT_15344 Class A/1 (Rhodopsin-like receptors) REACT_14828 G alpha (i) signalling events REACT_19231 GPCR downstream signaling REACT_19184 GPCR ligand binding REACT_21340 Peptide ligand-binding receptors REACT_14819 Signaling by GPCR REACT_14797

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 51   Blood vessel remodeling GO:0001974 Dendritic cell chemotaxis GO:0002407 Positive regulation of T-helper 1 type immune response GO:0002827 Negative regulation of type 2 immune response GO:0002829 Signal transducer activity GO:0004871 Receptor activity GO:0004872 G-protein coupled receptor activity GO:0004930 Chemokine receptor activity GO:0004950 Soluble fraction GO:0005625 Cytoplasm GO:0005737 Cytosol GO:0005829 Plasma membrane GO:0005886 Integral to plasma membrane GO:0005887 Cellular calcium ion homeostasis GO:0006874 Chemotaxis GO:0006935 Inflammatory response GO:0006954 Immune response GO:0006955 Cellular defense response GO:0006968 Negative regulation of adenylate cyclase activity GO:0007194 Elevation of cytosolic calcium ion concentration GO:0007204 JAK-STAT cascade GO:0007259 Response to wounding GO:0009611 Regulation of vascular endothelial growth factor production GO:0010574 Positive regulation of T cell chemotaxis GO:0010820 Integral to membrane GO:0016021 C-C chemokine receptor activity GO:0016493 Negative regulation of angiogenesis GO:0016525 Cytokine-mediated signaling pathway GO:0019221 Cellular homeostasis GO:0019725 Positive regulation of cell migration GO:0030335 Dendrite GO:0030425 CCR2 chemokine receptor binding GO:0031727 Positive regulation of interferon-gamma production GO:0032729 Positive regulation of interleukin-2 production GO:0032743 Monocyte extravasation GO:0035696 T-helper 17 cell chemotaxis GO:0035705 Positive regulation of tumor necrosis factor biosynthetic process GO:0042535 Protein homodimerization activity GO:0042803 Neuronal cell body GO:0043025 Perikaryon GO:0043204 Negative regulation of eosinophil degranulation GO:0043310 Astrocyte cell migration GO:0043615 Interspecies interaction between organisms GO:0044419 Positive regulation of alpha-beta T cell proliferation GO:0046641 Perinuclear region of cytoplasm GO:0048471 Positive regulation of inflammatory response GO:0050729 Positive regulation of T cell activation GO:0050870 Chemokine-mediated signaling pathway GO:0070098 Positive regulation of monocyte chemotaxis GO:0090026 Positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 Positive regulation of T cell extravasation GO:2000409

	KEGG Network: 2 Chemokine signaling pathway Human - 4062 Mouse - 4062 Rat - 4062 Cytokine-cytokine receptor interaction Human - 4060 Mouse - 4060 Rat - 4060
	Biocarta: 1 Selective expression of chemokine receptors during T-cell polarization Mouse
	Reactome: 7 Chemokine receptors bind chemokines REACT_15344 Class A/1 (Rhodopsin-like receptors) REACT_14828 G alpha (i) signalling events REACT_19231 GPCR downstream signaling REACT_19184 GPCR ligand binding REACT_21340 Peptide ligand-binding receptors REACT_14819 Signaling by GPCR REACT_14797
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 51 Blood vessel remodeling GO:0001974 Dendritic cell chemotaxis GO:0002407 Positive regulation of T-helper 1 type immune response GO:0002827 Negative regulation of type 2 immune response GO:0002829 Signal transducer activity GO:0004871 Receptor activity GO:0004872 G-protein coupled receptor activity GO:0004930 Chemokine receptor activity GO:0004950 Soluble fraction GO:0005625 Cytoplasm GO:0005737 Cytosol GO:0005829 Plasma membrane GO:0005886 Integral to plasma membrane GO:0005887 Cellular calcium ion homeostasis GO:0006874 Chemotaxis GO:0006935 Inflammatory response GO:0006954 Immune response GO:0006955 Cellular defense response GO:0006968 Negative regulation of adenylate cyclase activity GO:0007194 Elevation of cytosolic calcium ion concentration GO:0007204 JAK-STAT cascade GO:0007259 Response to wounding GO:0009611 Regulation of vascular endothelial growth factor production GO:0010574 Positive regulation of T cell chemotaxis GO:0010820 Integral to membrane GO:0016021 C-C chemokine receptor activity GO:0016493 Negative regulation of angiogenesis GO:0016525 Cytokine-mediated signaling pathway GO:0019221 Cellular homeostasis GO:0019725 Positive regulation of cell migration GO:0030335 Dendrite GO:0030425 CCR2 chemokine receptor binding GO:0031727 Positive regulation of interferon-gamma production GO:0032729 Positive regulation of interleukin-2 production GO:0032743 Monocyte extravasation GO:0035696 T-helper 17 cell chemotaxis GO:0035705 Positive regulation of tumor necrosis factor biosynthetic process GO:0042535 Protein homodimerization activity GO:0042803 Neuronal cell body GO:0043025 Perikaryon GO:0043204 Negative regulation of eosinophil degranulation GO:0043310 Astrocyte cell migration GO:0043615 Interspecies interaction between organisms GO:0044419 Positive regulation of alpha-beta T cell proliferation GO:0046641 Perinuclear region of cytoplasm GO:0048471 Positive regulation of inflammatory response GO:0050729 Positive regulation of T cell activation GO:0050870 Chemokine-mediated signaling pathway GO:0070098 Positive regulation of monocyte chemotaxis GO:0090026 Positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 Positive regulation of T cell extravasation GO:2000409

Type 1 Diabetes Publications: 11

• MCP-1 Upregulates Amylin Expression in Murine Pancreatic β Cells through ERK/JNK-AP1 and NF-κB Related Signaling Pathways Independent of CCR2.
  Cai K, Qi D, Hou X, Wang O, Chen J, Deng B, Qian L, Liu X, Le Y
  PLoS One. 2011
  PubMed ID: 21589925
   
  
• CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse.
  Solomon M, Balasa B, Sarvetnick N
  Autoimmunity. 2010
  PubMed ID: 19824873
   
  
• Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.
  Zhang N, Schröppel B, Lal G, Jakubzick C, Mao X, Chen D, Yin N, Jessberger R, Ochando JC, Ding Y, Bromberg JS
  Immunity. 2009
  PubMed ID: 19303390
   
  
• Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes.
  Martin AP, Rankin S, Pitchford S, Charo IF, Furtado GC, Lira SA
  Diabetes. 2008
  PubMed ID: 18633103
   
  
• Phenotypic and functional differences between wild-type and CCR2-/- dendritic cells: implications for islet transplantation.
  Fiorina P, Jurewicz M, Vergani A, Augello A, Paez J, Ricchiuti V, Tchipachvili V, Sayegh MH, Abdi R
  Transplantation. 2008
  PubMed ID: 18408585
   
  
• Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways.
  Schröppel B, Zhang N, Chen P, Zang W, Chen D, Hudkins KL, Kuziel WA, Sung R, Bromberg JS, Murphy B
  J Am Soc Nephrol. 2004
  PubMed ID: 15213273
   
  
• Polymorphisms of chemokine and chemokine receptor genes in Type 1 diabetes mellitus and its complications.
  Yang B, Houlberg K, Millward A, Demaine A
  Cytokine. 2004
  PubMed ID: 15135805
   
  
• Differential role of CCR2 in islet and heart allograft rejection: tissue specificity of chemokine/chemokine receptor function in vivo.
  Abdi R, Means TK, Ito T, Smith RN, Najafian N, Jurewicz M, Tchipachvili V, Charo I, Auchincloss H, Sayegh MH, Luster AD
  J Immunol. 2004
  PubMed ID: 14707046
   
  
• Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism.
  Lee I, Wang L, Wells AD, Ye Q, Han R, Dorf ME, Kuziel WA, Rollins BJ, Chen L, Hancock WW
  J Immunol. 2003
  PubMed ID: 14662900
   
  
• Lack of association of CCR2-64I and CCR5-Delta 32 with type 1 diabetes and latent autoimmune diabetes in adults.
  Gambelunghe G, Ghaderi M, Brozzetti A, Del Sindaco P, Gharizadeh B, Nyren P, Hjelmström P, Nikitina-Zake L, Sanjeevi CB, Falorni A, Umbria Type 1 Diabetes Registry
  Hum Immunol. 2003
  PubMed ID: 12770795
   
  
• Chemokine receptor CCR2 and CCR5 polymorphisms in children with insulin-dependent diabetes mellitus.
  Szalai C, Császár A, Czinner A, Szabó T, Pánczél P, Madácsy L, Falus A
  Pediatr Res. 1999
  PubMed ID: 10400139
   
  

Publications: 633

• CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis.
  Xu J, Lin SC, Chen J, Miao Y, Taffet GE, Entman ML, Wang Y
  Am J Physiol Heart Circ Physiol. 2011
  PubMed ID: 21572015
   
  
• Migration of fibrocytes in fibrogenic liver injury.
  Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK, Brenner DA, Kisseleva T
  Am J Pathol. 2011
  PubMed ID: 21703401
   
  
• The development of inducible bronchus-associated lymphoid tissue depends on IL-17.
  Rangel-Moreno J, Carragher DM, de la Luz Garcia-Hernandez M, Hwang JY, Kusser K, Hartson L, Kolls JK, Khader SA, Randall TD
  Nat Immunol. 2011
  PubMed ID: 21666689
   
  
• CCR2-64I gene polymorphism increase susceptibility to oral cancer.
  Chen MK, Yeh KT, Chiou HL, Lin CW, Chung TT, Yang SF
  Oral Oncol. 2011
  PubMed ID: 21570337
   
  
• Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus.
  Sezgin E, van Natta ML, Ahuja A, Lyon A, Srivastava S, Troyer JL, O'Brien SJ, Jabs DA, Studies of the Ocular Complications of AIDS Research Group
  Am J Ophthalmol. 2011
  PubMed ID: 21396623
   
  
• Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands.
  Shi C, Jia T, Mendez-Ferrer S, Hohl TM, Serbina NV, Lipuma L, Leiner I, Li MO, Frenette PS, Pamer EG
  Immunity. 2011
  PubMed ID: 21458307
   
  
• CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.
  Naert G, Rivest S
  J Neurosci. 2011
  PubMed ID: 21508244
   
  
• Identification of CCR2-binding features in Cytl1 by a CCL2-like chemokine model.
  Tomczak A, Pisabarro MT
  Proteins. 2011
  PubMed ID: 21322034
   
  
• DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
  Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, Misra S, Chaudhuri G, Buaas FW, Braun RE, Hinton DR, Zhang Q, Grossniklaus HE, Provis JM, Madigan MC, Milam AH, Justice NL, Albuquerque RJ, Blandford AD, Bogdanovich S, Hirano Y, Witta J, Fuchs E, Littman DR, Ambati BK, Rudin CM, Chong MM, Provost P, Kugel JF, Goodrich JA, Dunaief JL, Baffi JZ, Ambati J
  Nature. 2011
  PubMed ID: 21297615
   
  
• Genetic polymorphisms of inflammatory molecules in Tunisian kidney transplantation.
  Krichen H, Khazen D, Sfar I, Ben Abdallah T, Bardi R, Jendoubi-Ayed S, Makhlouf M, Abderrahim E, Aouadi H, Ayed K, Gorgi Y
  Transplant Proc. 2011
  PubMed ID: 21440726
   
  
• New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis.
  Sun L, Louie MC, Vannella KM, Wilke CA, LeVine AM, Moore BB, Shanley TP
  Am J Physiol Lung Cell Mol Physiol. 2011
  PubMed ID: 21131395
   
  
• Polymorphisms in chemokine and receptor genes and gastric cancer risk and survival in a high risk Polish population.
  Gawron AJ, Fought AJ, Lissowska J, Ye W, Zhang X, Chow WH, Beane Freeman LE, Hou L
  Scand J Gastroenterol. 2011
  PubMed ID: 21091093
   
  
• TLR2-dependent pathway of heterologous down-modulation for the CC chemokine receptors 1, 2, and 5 in human blood monocytes.
  Fox JM, Letellier E, Oliphant CJ, Signoret N
  Blood. 2011
  PubMed ID: 21148810
   
  
• Role of CCR2 and IL-8 in acute lung injury: a new mechanism and therapeutic target.
  Shen Y, Wang D, Wang X
  Expert Rev Respir Med. 2011
  PubMed ID: 21348591
   
  
• The role of the CCR2 gene polymorphism in abdominal aortic aneurysms.
  Katrancioglu N, Manduz S, Karahan O, Yilmaz MB, Sezgin I, Bagci G, Berkan O
  Angiology. 2011
  PubMed ID: 21220372
   
  
• Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
  Islam SA, Chang DS, Colvin RA, Byrne MH, McCully ML, Moser B, Lira SA, Charo IF, Luster AD
  Nat Immunol. 2011
  PubMed ID: 21217759
   
  
• IL-1α modulates neutrophil recruitment in chronic inflammation induced by hydrocarbon oil.
  Lee PY, Kumagai Y, Xu Y, Li Y, Barker T, Liu C, Sobel ES, Takeuchi O, Akira S, Satoh M, Reeves WH
  J Immunol. 2011
  PubMed ID: 21191074
   
  
• Distinct CCR2(+) Gr1(+) cells control growth of the Yersinia pestis ΔyopM mutant in liver and spleen during systemic plague.
  Ye Z, Uittenbogaard AM, Cohen DA, Kaplan AM, Ambati J, Straley SC
  Infect Immun. 2011
  PubMed ID: 21149593
   
  
• MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.
  Monzon ME, Forteza RM, Casalino-Matsuda SM
  Am J Physiol Lung Cell Mol Physiol. 2011
  PubMed ID: 21097527
   
  
• Interferon-γ links ultraviolet radiation to melanomagenesis in mice.
  Zaidi MR, Davis S, Noonan FP, Graff-Cherry C, Hawley TS, Walker RL, Feigenbaum L, Fuchs E, Lyakh L, Young HA, Hornyak TJ, Arnheiter H, Trinchieri G, Meltzer PS, De Fabo EC, Merlino G
  Nature. 2011
  PubMed ID: 21248750
   
  
• Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration.
  Moreaux J, Hose D, Kassambara A, Reme T, Moine P, Requirand G, Goldschmidt H, Klein B
  Blood. 2011
  PubMed ID: 21097672
   
  
• Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue.
  Iijima N, Mattei LM, Iwasaki A
  Proc Natl Acad Sci U S A. 2011
  PubMed ID: 21173243
   
  
• Association between the CCR2-Val64Ile polymorphism and susceptibility to HIV-1 infection: a meta-analysis.
  Ding DL, Liu SJ, Zhu HZ
  Mol Med Report. 2011
  PubMed ID: 21461583
   
  
• In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2.
  Berencsi K, Rani P, Zhang T, Gross L, Mastrangelo M, Meropol NJ, Herlyn D, Somasundaram R
  J Transl Med. 2011
  PubMed ID: 21450101
   
  
• Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.
  Malhotra R, Hu L, Song W, Brill I, Mulenga J, Allen S, Hunter E, Shrestha S, Tang J, Kaslow RA
  Retrovirology. 2011
  PubMed ID: 21429204
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection.
  Osterholzer JJ, Chen GH, Olszewski MA, Zhang YM, Curtis JL, Huffnagle GB, Toews GB
  Am J Pathol. 2011
  PubMed ID: 21224057
   
  
• Differential effect of telmisartan and amlodipine on monocyte chemoattractant protein-1 and peroxisome proliferator-activated receptor-gamma gene expression in peripheral monocytes in patients with essential hypertension.
  Marketou ME, Kontaraki JE, Tsakountakis NA, Zacharis EA, Kochiadakis GE, Arfanakis DA, Parthenakis F, Chlouverakis G, Vardas PE
  Am J Cardiol. 2011
  PubMed ID: 21146687
   
  
• Chemokine receptor Ccr2 is critical for monocyte accumulation and survival in West Nile virus encephalitis.
  Lim JK, Obara CJ, Rivollier A, Pletnev AG, Kelsall BL, Murphy PM
  J Immunol. 2011
  PubMed ID: 21131425
   
  
• Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.
  Delano MJ, Thayer T, Gabrilovich S, Kelly-Scumpia KM, Winfield RD, Scumpia PO, Cuenca AG, Warner E, Wallet SM, Wallet MA, O'Malley KA, Ramphal R, Clare-Salzer M, Efron PA, Mathews CE, Moldawer LL
  J Immunol. 2011
  PubMed ID: 21106855
   
  
• CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection.
  Lin KL, Sweeney S, Kang BD, Ramsburg E, Gunn MD
  J Immunol. 2011
  PubMed ID: 21098218
   
  
• Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury.
  Lu H, Huang D, Saederup N, Charo IF, Ransohoff RM, Zhou L
  FASEB J. 2011
  PubMed ID: 20889618
   
  
• CCL2 and CCR2 variants are associated with skeletal muscle strength and change in strength with resistance training.
  Harmon BT, Orkunoglu-Suer EF, Adham K, Larkin JS, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Hubal MJ, Tosi LL, Hoffman EP, Devaney JM
  J Appl Physiol. 2010
  PubMed ID: 20947712
   
  
• Tissue distribution and expression of paraoxonases and chemokines in mouse: the ubiquitous and joint localisation suggest a systemic and coordinated role.
  Rodríguez-Sanabria F, Rull A, Beltrán-Debón R, Aragonès G, Camps J, Mackness B, Mackness M, Joven J
  J Mol Histol. 2010
  PubMed ID: 20931267
   
  
• Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice.
  Chen C, Liu Y, Liu Y, Zheng P
  J Clin Invest. 2010
  PubMed ID: 20972332
   
  
• CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice.
  Kang YS, Lee MH, Song HK, Ko GJ, Kwon OS, Lim TK, Kim SH, Han SY, Han KH, Lee JE, Han JY, Kim HK, Cha DR
  Kidney Int. 2010
  PubMed ID: 20686445
   
  
• Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b.
  Craddock JA, Lu A, Bear A, Pule M, Brenner MK, Rooney CM, Foster AE
  J Immunother. 2010
  PubMed ID: 20842059
   
  
• A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
  Romero R, Friel LA, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, Bartlett J, Salisbury BA, Anant MK, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
  Am J Obstet Gynecol. 2010
  PubMed ID: 20673868
   
  
• Gammadelta T cells but not NK cells are essential for cell-mediated immunity against Plasmodium chabaudi malaria.
  Weidanz WP, LaFleur G, Brown A, Burns JM, Gramaglia I, van der Heyde HC
  Infect Immun. 2010
  PubMed ID: 20660608
   
  
• Lack of association between monocyte protein-1 (MCP-1) -2518 A>G chemoattractant and C-C chemokine receptor 2 (CCR2) Val64Ile polymorphisms and multiple sclerosis in a Tunisian population.
  Messadi A, Fekih-Mrissa N, Kallel A, Bouguerra C, Sediri Y, Zaweli J, Laayouni S, Nciri B, Yedeas M, Mrissa R, Jemaa R, Kaabachi N, Gritli N
  J Clin Neurosci. 2010
  PubMed ID: 20637631
   
  
• Monocyte chemoattractant protein-1/CC chemokine ligand 2 enhances apoptotic cell removal by macrophages through Rac1 activation.
  Tanaka T, Terada M, Ariyoshi K, Morimoto K
  Biochem Biophys Res Commun. 2010
  PubMed ID: 20691665
   
  
• Genetic polymorphism of CCR2-64I increased the susceptibility of hepatocellular carcinoma.
  Yeh CB, Tsai HT, Chen YC, Kuo WH, Chen TY, Hsieh YH, Chou MC, Yang SF
  J Surg Oncol. 2010
  PubMed ID: 20740585
   
  
• Association of monocyte chemotactic protein-1 and CC chemokine receptor 2 gene variants with preeclampsia.
  Agachan B, Attar R, Isbilen E, Aydogan HY, Sozen S, Gurdol F, Isbir T
  J Interferon Cytokine Res. 2010
  PubMed ID: 20726788
   
  
• Regulation of skeletal muscle regeneration by CCR2-activating chemokines is directly related to macrophage recruitment.
  Martinez CO, McHale MJ, Wells JT, Ochoa O, Michalek JE, McManus LM, Shireman PK
  Am J Physiol Regul Integr Comp Physiol. 2010
  PubMed ID: 20631294
   
  
• Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts.
  Ksiazkiewicz M, Gottfried E, Kreutz M, Mack M, Hofstaedter F, Kunz-Schughart LA
  Immunobiology. 2010
  PubMed ID: 20605053
   
  
• Effects of the CC chemokine receptor 2 in mice deficient for the myelin protein zero (P0).
  Oberländer M, Berghoff M
  Mol Cell Neurosci. 2010
  PubMed ID: 20553884
   
  
• Blunt chest trauma induces mediator-dependent monocyte migration to the lung.
  Seitz DH, Niesler U, Palmer A, Sulger M, Braumüller ST, Perl M, Gebhard F, Knöferl MW
  Crit Care Med. 2010
  PubMed ID: 20543668
   
  
• Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism.
  Beckers MM, Ruven HJ, Haas FJ, Doevendans PA, ten Cate H, Prins MH, Biesma DH
  Eur J Intern Med. 2010
  PubMed ID: 20603037
   
  
• Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS.
  Sezgin E, Hendrickson SL, Jabs DA, Van Natta ML, Lewis RA, Troyer JL, O'Brien SJ, SOCA Research Group
  J Acquir Immune Defic Syndr. 2010
  PubMed ID: 20531015
   
  
• Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.
  Wang Y, Fu W, Xie F, Wang Y, Chu X, Wang H, Shen M, Wang Y, Wang Y, Sun W, Lei R, Yang L, Wu H, Foo J, Liu J, Jin L, Huang W
  J Hum Genet. 2010
  PubMed ID: 20485444
   
  
• The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases.
  Conductier G, Blondeau N, Guyon A, Nahon JL, Rovère C
  J Neuroimmunol. 2010
  PubMed ID: 20681057
   
  
• Tickets to the brain: role of CCR2 and CX3CR1 in myeloid cell entry in the CNS.
  Prinz M, Priller J
  J Neuroimmunol. 2010
  PubMed ID: 20554025
   
  
• Multiple roles for CCR2 during fracture healing.
  Xing Z, Lu C, Hu D, Yu YY, Wang X, Colnot C, Nakamura M, Wu Y, Miclau T, Marcucio RS
  Dis Model Mech. 2010
  PubMed ID: 20354109
   
  
• APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors.
  Spector SA, Singh KK, Gupta S, Cystique LA, Jin H, Letendre S, Schrier R, Wu Z, Hong KX, Yu X, Shi C, Heaton RK, HNRC Group
  AIDS. 2010
  PubMed ID: 20442634
   
  
• An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation.
  Platt AM, Bain CC, Bordon Y, Sester DP, Mowat AM
  J Immunol. 2010
  PubMed ID: 20483766
   
  
• Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.
  Röhrl J, Yang D, Oppenheim JJ, Hehlgans T
  J Immunol. 2010
  PubMed ID: 20483750
   
  
• Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.
  Yao H, Yang Y, Kim KJ, Bethel-Brown C, Gong N, Funa K, Gendelman HE, Su TP, Wang JQ, Buch S
  Blood. 2010
  PubMed ID: 20354174
   
  
• Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
  Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
  Pediatr Pulmonol. 2010
  PubMed ID: 20503287
   
  
• Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression.
  Shi C, Velázquez P, Hohl TM, Leiner I, Dustin ML, Pamer EG
  J Immunol. 2010
  PubMed ID: 20435926
   
  
• The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo.
  Collington SJ, Hallgren J, Pease JE, Jones TG, Rollins BJ, Westwick J, Austen KF, Williams TJ, Gurish MF, Weller CL
  J Immunol. 2010
  PubMed ID: 20427772
   
  
• CCR2 plays a critical role in dendritic cell maturation: possible role of CCL2 and NF-kappa B.
  Jimenez F, Quinones MP, Martinez HG, Estrada CA, Clark K, Garavito E, Ibarra J, Melby PC, Ahuja SS
  J Immunol. 2010
  PubMed ID: 20404272
   
  
• Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population.
  Antonelli LR, Gigliotti Rothfuchs A, Gonçalves R, Roffê E, Cheever AW, Bafica A, Salazar AM, Feng CG, Sher A
  J Clin Invest. 2010
  PubMed ID: 20389020
   
  
• Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.
  Romero R, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Chaiworapongsa T, Pearce BD, Friel LA, Bartlett J, Anant MK, Salisbury BA, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
  Am J Obstet Gynecol. 2010
  PubMed ID: 20452482
   
  
• Antigen-presenting dendritic cells rescue CD4-depleted CCR2-/- mice from lethal Histoplasma capsulatum infection.
  Szymczak WA, Deepe GS
  Infect Immun. 2010
  PubMed ID: 20194586
   
  
• Genetic variation at the CCR5/CCR2 gene cluster and risk of psoriasis and psoriatic arthritis.
  Soto-Sánchez J, Santos-Juanes J, Coto-Segura P, Coto E, Díaz M, Rodríguez I, Alvarez V
  Cytokine. 2010
  PubMed ID: 20153665
   
  
• Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.
  Wang Y, Luk AO, Ma RC, So WY, Tam CH, Ng MC, Yang X, Baum L, Lam V, Tong PC, Chan JC
  Diabet Med. 2010
  PubMed ID: 20536507
   
  
• HIV infection and host genetic mutation among injecting drug-users of northeastern states of India.
  Sarkar K, Das SS, Pal R, Bal B, Madhusudan P, Chakraborti S
  J Health Popul Nutr. 2010
  PubMed ID: 20411675
   
  
• CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice.
  Si Y, Tsou CL, Croft K, Charo IF
  J Clin Invest. 2010
  PubMed ID: 20234092
   
  
• Association of the MCP-1 -2518 A/G polymorphism and no association of its receptor CCR2 -64 V/I polymorphism with lupus nephritis.
  Malafronte P, Vieira JM, Pereira AC, Krieger JE, Barros RT, Woronik V
  J Rheumatol. 2010
  PubMed ID: 20231199
   
  
• Multiple common variants for celiac disease influencing immune gene expression.
  Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA
  Nat Genet. 2010
  PubMed ID: 20190752
   
  
• C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis.
  Obstfeld AE, Sugaru E, Thearle M, Francisco AM, Gayet C, Ginsberg HN, Ables EV, Ferrante AW
  Diabetes. 2010
  PubMed ID: 20103702
   
  
• C-C chemokine receptor 2 inhibitor improves diet-induced development of insulin resistance and hepatic steatosis in mice.
  Tamura Y, Sugimoto M, Murayama T, Minami M, Nishikaze Y, Ariyasu H, Akamizu T, Kita T, Yokode M, Arai H
  J Atheroscler Thromb. 2010
  PubMed ID: 20179360
   
  
• Roles of CC chemokine receptors (CCRs) on lipopolysaccharide-induced acute lung injury.
  Yang D, Tong L, Wang D, Wang Y, Wang X, Bai C
  Respir Physiol Neurobiol. 2010
  PubMed ID: 20152938
   
  
• CCL2 and CCR2 Polymorphisms are Associated with Markers of Exercise-Induced Skeletal Muscle Damage.
  Hubal MJ, Devaney JM, Hoffman EP, Zambraski EJ, Gordish-Dressman H, Kearns AK, Larkin JS, Adham K, Patel RR, Clarkson PM
  J Appl Physiol. 2010
  PubMed ID: 20339010
   
  
• Association of CCL2 and CCR2 gene variants with endometrial cancer in Turkish women.
  Attar R, Agachan B, Kuran SB, Cacina C, Sozen S, Yurdum LM, Attar E, Isbir T
  In Vivo. 2010
  PubMed ID: 20364004
   
  
• Linkage and haplotype analysis for chemokine receptors clustered on chromosome 3p21.3 and transmitted in family pedigrees with asthma and atopy.
  Al-Abdulhadi SA, Al-Rabia MW
  Ann Saudi Med. 2010
  PubMed ID: 20220260
   
  
• An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice.
  Tateya S, Tamori Y, Kawaguchi T, Kanda H, Kasuga M
  Endocrinology. 2010
  PubMed ID: 20056828
   
  
• Chemokine polymorphisms and lymphoma: a pooled analysis.
  Bracci PM, Skibola CF, Conde L, Halperin E, Lightfoot T, Smith A, Paynter RA, Skibola DR, Agana L, Roman E, Kane E, Wiencke JK
  Leuk Lymphoma. 2010
  PubMed ID: 20038229
   
  
• Distribution of CCR5-Delta32, CCR5m303A, CCR2-64I and SDF1-3'A in HIV-1 infected and uninfected high-risk Uighurs in Xinjiang, China.
  Tan XH, Zhang JY, Di CH, Hu AR, Yang L, Qu S, Zhao RL, Yang PR, Guo SX
  Infect Genet Evol. 2010
  PubMed ID: 19958843
   
  
• Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks.
  Semple BD, Kossmann T, Morganti-Kossmann MC
  J Cereb Blood Flow Metab. 2010
  PubMed ID: 19904283
   
  
• Effect of genetic variants of chemokine receptors on the development of myocardial infarction in Turkish population.
  Karaali ZE, Sozen S, Yurdum M, Cacina C, Toptas B, Gok O, Agachan B
  Mol Biol Rep. 2010
  PubMed ID: 20182805
   
  
• Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.
  Salem ML, Al-Khami AA, El-Naggar SA, Díaz-Montero CM, Chen Y, Cole DJ
  J Immunol. 2010
  PubMed ID: 20083664
   
  
• CCR2 deficiency results in increased osteolysis in experimental periapical lesions in mice.
  Garlet TP, Fukada SY, Saconato IF, Avila-Campos MJ, da Silva TA, Garlet GP, Cunha Fde Q
  J Endod. 2010
  PubMed ID: 20113782
   
  
• Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion.
  Bamboat ZM, Ocuin LM, Balachandran VP, Obaid H, Plitas G, DeMatteo RP
  J Clin Invest. 2010
  PubMed ID: 20093775
   
  
• A mouse model of lethal synergism between influenza virus and Haemophilus influenzae.
  Lee LN, Dias P, Han D, Yoon S, Shea A, Zakharov V, Parham D, Sarawar SR
  Am J Pathol. 2010
  PubMed ID: 20042666
   
  
• Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection.
  Goodyear A, Jones A, Troyer R, Bielefeldt-Ohmann H, Dow S
  J Immunol. 2010
  PubMed ID: 20042590
   
  
• Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance imaging assessment.
  Olzinski AR, Turner GH, Bernard RE, Karr H, Cornejo CA, Aravindhan K, Hoang B, Ringenberg MA, Qin P, Goodman KB, Willette RN, Macphee CH, Jucker BM, Sehon CA, Gough PJ
  Arterioscler Thromb Vasc Biol. 2010
  PubMed ID: 19965779
   
  
• CCR2 receptor blockade alters blood monocyte subpopulations but does not affect atherosclerotic lesions in apoE(-/-) mice.
  Aiello RJ, Perry BD, Bourassa PA, Robertson A, Weng W, Knight DR, Smith AH, Frederick KS, Kalgutkar A, Gladue RP
  Atherosclerosis. 2010
  PubMed ID: 19837409
   
  
• Combined association of CCR2-V64I and MCP-1-2518A/G polymorphisms with generalised aggressive periodontitis in Chinese.
  Zhu XL, Meng HX, Xu L, Zhang L, Chen ZB, Shi D, Feng XH
  Chin J Dent Res. 2010
  PubMed ID: 21264360
   
  
• Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice.
  Guabiraba R, Marques RE, Besnard AG, Fagundes CT, Souza DG, Ryffel B, Teixeira MM
  PLoS One. 2010
  PubMed ID: 21206747
   
  
• Blocking spinal CCR2 with AZ889 reversed hyperalgesia in a model of neuropathic pain.
  Serrano A, Paré M, McIntosh F, Elmes SJ, Martino G, Jomphe C, Lessard E, Lembo PM, Vaillancourt F, Perkins MN, Cao CQ
  Mol Pain. 2010
  PubMed ID: 21143971
   
  
• Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice.
  Saederup N, Cardona AE, Croft K, Mizutani M, Cotleur AC, Tsou CL, Ransohoff RM, Charo IF
  PLoS One. 2010
  PubMed ID: 21060874
   
  
• Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994.
  Ned RM, Yesupriya A, Imperatore G, Smelser DT, Moonesinghe R, Chang MH, Dowling NF
  BMC Med Genet. 2010
  PubMed ID: 21054877
   
  
• Filamin a binds to CCR2B and regulates its internalization.
  Minsaas L, Planagumà J, Madziva M, Krakstad BF, Masià-Balagué M, Katz AA, Aragay AM
  PLoS One. 2010
  PubMed ID: 20808917
   
  
• Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling.
  Bosschaerts T, Guilliams M, Stijlemans B, Morias Y, Engel D, Tacke F, Hérin M, De Baetselier P, Beschin A
  PLoS Pathog. 2010
  PubMed ID: 20714353
   
  
• Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children.
  Mamtani M, Matsubara T, Shimizu C, Furukawa S, Akagi T, Onouchi Y, Hata A, Fujino A, He W, Ahuja SK, Burns JC
  PLoS One. 2010
  PubMed ID: 20628649
   
  
• CCR2-V64I polymorphism is associated with increased risk of cervical cancer but not with HPV infection or pre-cancerous lesions in African women.
  Chatterjee K, Dandara C, Hoffman M, Williamson AL
  BMC Cancer. 2010
  PubMed ID: 20537184
   
  
• Inhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy and transplant rejection.
  Dai E, Liu LY, Wang H, McIvor D, Sun YM, Macaulay C, King E, Munuswamy-Ramanujam G, Bartee MY, Williams J, Davids J, Charo I, McFadden G, Esko JD, Lucas AR
  PLoS One. 2010
  PubMed ID: 20463901
   
  
• CCR2-64I is a risk factor for development of bladder cancer.
  Narter KF, Agachan B, Sozen S, Cincin ZB, Isbir T
  Genet Mol Res. 2010
  PubMed ID: 20449800
   
  
• CCR2 and coronary artery disease: a woscops substudy.
  Dow DJ, McMahon AD, Gray IC, Packard CJ, Groot PH
  BMC Res Notes. 2010
  PubMed ID: 20181074
   
  
• Do human polyoma viruses and human immunodeficiency virus share common co-receptors?
  Borissov K, Tsekov I, Gavazova R, Kalvatchev Z, Argirova R
  J Med Virol. 2010
  PubMed ID: 19950235
   
  
• Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria.
  Sponaas AM, Freitas do Rosario AP, Voisine C, Mastelic B, Thompson J, Koernig S, Jarra W, Renia L, Mauduit M, Potocnik AJ, Langhorne J
  Blood. 2009
  PubMed ID: 19837977
   
  
• MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity.
  Westcott DJ, Delproposto JB, Geletka LM, Wang T, Singer K, Saltiel AR, Lumeng CN
  J Exp Med. 2009
  PubMed ID: 19995956
   
  
• Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network.
  Chorro L, Sarde A, Li M, Woollard KJ, Chambon P, Malissen B, Kissenpfennig A, Barbaroux JB, Groves R, Geissmann F
  J Exp Med. 2009
  PubMed ID: 19995948
   
  
• Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes.
  Osterholzer JJ, Chen GH, Olszewski MA, Curtis JL, Huffnagle GB, Toews GB
  J Immunol. 2009
  PubMed ID: 19933856
   
  
• An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.
  Tieu BC, Lee C, Sun H, Lejeune W, Recinos A, Ju X, Spratt H, Guo DC, Milewicz D, Tilton RG, Brasier AR
  J Clin Invest. 2009
  PubMed ID: 19920349
   
  
• Inhibition of dynamin prevents CCL2-mediated endocytosis of CCR2 and activation of ERK1/2.
  García Lopez MA, Aguado Martínez A, Lamaze C, Martínez-A C, Fischer T
  Cell Signal. 2009
  PubMed ID: 19643177
   
  
• Immunohistochemical detection of CCR2 and CX3CR1 in sepsis-induced lung injury.
  An JL, Ishida Y, Kimura A, Tsokos M, Kondo T
  Forensic Sci Int. 2009
  PubMed ID: 19733456
   
  
• Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment.
  Weiss JM, Back TC, Scarzello AJ, Subleski JJ, Hall VL, Stauffer JK, Chen X, Micic D, Alderson K, Murphy WJ, Wiltrout RH
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19892741
   
  
• FROUNT is a common regulator of CCR2 and CCR5 signaling to control directional migration.
  Toda E, Terashima Y, Sato T, Hirose K, Kanegasaki S, Matsushima K
  J Immunol. 2009
  PubMed ID: 19841162
   
  
• Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.
  Sohy D, Yano H, de Nadai P, Urizar E, Guillabert A, Javitch JA, Parmentier M, Springael JY
  J Biol Chem. 2009
  PubMed ID: 19758998
   
  
• Interplay of CCR2 signaling and local shear force determines vein graft neointimal hyperplasia in vivo.
  Jiang Z, Yu P, Tao M, Ifantides C, Ozaki CK, Berceli SA
  FEBS Lett. 2009
  PubMed ID: 19822149
   
  
• Type I interferon modulates monocyte recruitment and maturation in chronic inflammation.
  Lee PY, Li Y, Kumagai Y, Xu Y, Weinstein JS, Kellner ES, Nacionales DC, Butfiloski EJ, van Rooijen N, Akira S, Sobel ES, Satoh M, Reeves WH
  Am J Pathol. 2009
  PubMed ID: 19808647
   
  
• Bone marrow-derived cell-specific chemokine (C-C motif) receptor-2 expression is required for arteriolar remodeling.
  Nickerson MM, Song J, Meisner JK, Bajikar S, Burke CW, Shuptrine CW, Owens GK, Skalak TC, Price RJ
  Arterioscler Thromb Vasc Biol. 2009
  PubMed ID: 19734197
   
  
• Lipid bodies in oxidized LDL-induced foam cells are leukotriene-synthesizing organelles: a MCP-1/CCL2 regulated phenomenon.
  Silva AR, Pacheco P, Vieira-de-Abreu A, Maya-Monteiro CM, D'Alegria B, Magalhães KG, de Assis EF, Bandeira-Melo C, Castro-Faria-Neto HC, Bozza PT
  Biochim Biophys Acta. 2009
  PubMed ID: 19573621
   
  
• Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone.
  Lu X, Kang Y
  J Biol Chem. 2009
  PubMed ID: 19720836
   
  
• CCR2, MCP-1, SDF-1a & DC-SIGN gene polymorphisms in HIV-1 infected patients with & without tuberculosis.
  Alagarasu K, Selvaraj P, Swaminathan S, Raghavan S, Narendran G, Narayanan PR
  Indian J Med Res. 2009
  PubMed ID: 19942750
   
  
• Turn-over of meningeal and perivascular macrophages in the brain of MCP-1-, CCR-2- or double knockout mice.
  Schilling M, Strecker JK, Ringelstein EB, Kiefer R, Schäbitz WR
  Exp Neurol. 2009
  PubMed ID: 19615366
   
  
• CCR3, CCR2A and macrophage inflammatory protein (MIP)-1a, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE) .
  Xu JH, Long L, Tang YC, Zhang JT, Hut HT, Tang FR
  Neuropathol Appl Neurobiol. 2009
  PubMed ID: 19490431
   
  
• Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.
  Cakarova L, Marsh LM, Wilhelm J, Mayer K, Grimminger F, Seeger W, Lohmeyer J, Herold S
  Am J Respir Crit Care Med. 2009
  PubMed ID: 19590023
   
  
• The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice.
  Schilling M, Strecker JK, Ringelstein EB, Schäbitz WR, Kiefer R
  Brain Res. 2009
  PubMed ID: 19559679
   
  
• Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner.
  Baba T, Nakamoto Y, Mukaida N
  J Immunol. 2009
  PubMed ID: 19675159
   
  
• Monocyte chemoattractant protein-1 (MCP-1), not MCP-3, is the primary chemokine required for monocyte recruitment in mouse peritonitis induced with thioglycollate or zymosan A.
  Takahashi M, Galligan C, Tessarollo L, Yoshimura T
  J Immunol. 2009
  PubMed ID: 19641140
   
  
• Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics.
  Batra J, Ghosh B
  Genomics. 2009
  PubMed ID: 19520154
   
  
• Development of experimental autoimmune uveitis: efficient recruitment of monocytes is independent of CCR2.
  Dagkalis A, Wallace C, Xu H, Liebau S, Manivannan A, Stone MA, Mack M, Liversidge J, Crane IJ
  Invest Ophthalmol Vis Sci. 2009
  PubMed ID: 19357362
   
  
• Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort.
  Amundsen SS, Rundberg J, Adamovic S, Gudjónsdóttir AH, Ascher H, Ek J, Nilsson S, Lie BA, Naluai AT, Sollid LM
  Genes Immun. 2009
  PubMed ID: 19693089
   
  
• Regulation of inflammatory monocyte/macrophage recruitment from the bone marrow during murine cytomegalovirus infection: role for type I interferons in localized induction of CCR2 ligands.
  Crane MJ, Hokeness-Antonelli KL, Salazar-Mather TP
  J Immunol. 2009
  PubMed ID: 19620305
   
  
• Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
  Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
  Eur Urol. 2009
  PubMed ID: 19692168
   
  
• CCR2-64I allele is associated with the progression of AIDS in a Han Chinese population.
  Xu L, Qiao Y, Zhang X, Sun H, Wang J, Sun D, Jin Y, Yu Y, Chen F, Bai J, Ling H, Wang K, Fu S
  Mol Biol Rep. 2009
  PubMed ID: 19669591
   
  
• The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
  Szymczak WA, Deepe GS
  J Immunol. 2009
  PubMed ID: 19587014
   
  
• Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.
  Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y
  Int J Mol Med. 2009
  PubMed ID: 19578796
   
  
• Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice.
  Luckow B, Hänggli A, Maier H, Chilla S, Loewe RP, Dehmel S, Schlöndorff D, Loetscher P, Zerwes HG, Müller M
  Genesis. 2009
  PubMed ID: 19517561
   
  
• Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling.
  Song XY, Lee SY, Ma RC, So WY, Cai JH, Tam C, Lam V, Ying W, Ng MC, Chan JC
  Diabetologia. 2009
  PubMed ID: 19479237
   
  
• Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis.
  McDougal KE, Fallin MD, Moller DR, Song Z, Cutler DJ, Steiner LL, Cutting GR, ACCESS Research Group
  J Invest Dermatol. 2009
  PubMed ID: 19225544
   
  
• PTEN identified as important risk factor of chronic obstructive pulmonary disease.
  Hosgood HD, Menashe I, He X, Chanock S, Lan Q
  Respir Med. 2009
  PubMed ID: 19625176
   
  
• CCR3 is a target for age-related macular degeneration diagnosis and therapy.
  Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J
  Nature. 2009
  PubMed ID: 19525930
   
  
• A candidate gene association study of 77 polymorphisms in migraine.
  Schürks M, Kurth T, Buring JE, Zee RY
  J Pain. 2009
  PubMed ID: 19559392
   
  
• A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
  Izhak L, Wildbaum G, Zohar Y, Anunu R, Klapper L, Elkeles A, Seagal J, Yefenof E, Ayalon-Soffer M, Karin N
  J Immunol. 2009
  PubMed ID: 19535619
   
  
• The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability.
  Lee EY, Chung CH, Khoury CC, Yeo TK, Pyagay PE, Wang A, Chen S
  Am J Physiol Renal Physiol. 2009
  PubMed ID: 19420107
   
  
• Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain.
  Jung H, Bhangoo S, Banisadr G, Freitag C, Ren D, White FA, Miller RJ
  J Neurosci. 2009
  PubMed ID: 19553445
   
  
• C-C chemokine receptor 2 expression by circulating monocytes influences atherosclerosis in patients on chronic hemodialysis.
  Okumoto S, Taniguchi Y, Nakashima A, Masaki T, Ito T, Ogawa T, Takasugi N, Kohno N, Yorioka N
  Ther Apher Dial. 2009
  PubMed ID: 19527467
   
  
• CCR2-64I polymorphism is associated with lower maternal HIV-1 viral load and reduced vertical HIV-1 transmission.
  Mabuka JM, Mackelprang RD, Lohman-Payne B, Majiwa M, Bosire R, John-Stewart G, Rowland-Jones S, Overbaugh J, Farquhar C
  J Acquir Immune Defic Syndr. 2009
  PubMed ID: 19465829
   
  
• Opposite roles of CCR2 and CX3CR1 macrophages in alkali-induced corneal neovascularization.
  Lu P, Li L, Liu G, van Rooijen N, Mukaida N, Zhang X
  Cornea. 2009
  PubMed ID: 19421039
   
  
• A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).
  Yamamoto R, Nagasawa Y, Shoji T, Inoue K, Uehata T, Kaneko T, Okada T, Yamauchi A, Tsubakihara Y, Imai E, Isaka Y, Rakugi H
  Nephrol Dial Transplant. 2009
  PubMed ID: 19420105
   
  
• Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice.
  Mitchell C, Couton D, Couty JP, Anson M, Crain AM, Bizet V, Rénia L, Pol S, Mallet V, Gilgenkrantz H
  Am J Pathol. 2009
  PubMed ID: 19359521
   
  
• Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
  Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
  Environ Mol Mutagen. 2009
  PubMed ID: 19170196
   
  
• [Change of serum MCP-1 level and CCR2 protein expression in isolated monocytes in patients with acute coronary syndrome].
  Wang Y, Liu Z, Yang T
  Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009
  PubMed ID: 19411748
   
  
• Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.
  Binder NB, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig TM, Mack M, Erben RG, Smolen JS, Redlich K
  Nat Med. 2009
  PubMed ID: 19330010
   
  
• Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.
  Zee RY, Bubes V, Shrivastava S, Ridker PM, Glynn RJ
  Clin Chim Acta. 2009
  PubMed ID: 19263529
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
  Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R
  Pediatr Infect Dis J. 2009
  PubMed ID: 19258923
   
  
• Cytokine (IL-10 -1082 and -819) and chemokine receptor (CCR2 and CCR5) gene polymorphism in North Indian patients with end-stage renal disease.
  Manchanda PK, Singh R, Mittal RD
  DNA Cell Biol. 2009
  PubMed ID: 19196047
   
  
• Differential upregulation of chemokine receptors on CD56 NK cells and their transmigration to the site of infection in tuberculous pleurisy.
  Pokkali S, Das SD, Selvaraj A
  FEMS Immunol Med Microbiol. 2009
  PubMed ID: 19159432
   
  
• A CCR2/CCR5 antagonist attenuates an increase in angiotensin II-induced CD11b+ monocytes from atherogenic ApoE-/- mice.
  Major TC, Olszewski B, Rosebury-Smith WS
  Cardiovasc Drugs Ther. 2009
  PubMed ID: 19052854
   
  
• TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection.
  Aldridge JR, Moseley CE, Boltz DA, Negovetich NJ, Reynolds C, Franks J, Brown SA, Doherty PC, Webster RG, Thomas PG
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19279209
   
  
• A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
  Wang X, Cheng S, Brophy VH, Erlich HA, Mannhalter C, Berger K, Lalouschek W, Browner WS, Shi Y, Ringelstein EB, Kessler C, Luedemann J, Lindpaintner K, Liu L, Ridker PM, Zee RY, Cook NR, RMS Stroke SNP Consortium
  Stroke. 2009
  PubMed ID: 19131662
   
  
• Alteration in iron metabolism during retinal degeneration in rd10 mouse.
  Deleon E, Lederman M, Berenstein E, Meir T, Chevion M, Chowers I
  Invest Ophthalmol Vis Sci. 2009
  PubMed ID: 18997094
   
  
• Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation.
  D'Mello C, Le T, Swain MG
  J Neurosci. 2009
  PubMed ID: 19228962
   
  
• MCP-1 and CCR2 gene polymorphisms in Czech patients with allergic disorders.
  Holla LI, Mrazek F, Petrek M
  Int J Immunogenet. 2009
  PubMed ID: 19055601
   
  
• Screening the single nucleotide polymorphisms in patients with internal carotid artery stenosis by oligonucleotide-based custom DNA array.
  Nakai K, Oyanagi M, Hitomi J, Ogasawara K, Inoue T, Kobayashi M, Nakai K, Suwabe A, Habano W, Baba T, Yoshida H, Ogawa A
  Bioinform Biol Insights. 2009
  PubMed ID: 20066125
   
  
• Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus.
  Foresti ML, Arisi GM, Katki K, Montañez A, Sanchez RM, Shapiro LA
  J Neuroinflammation. 2009
  PubMed ID: 20034406
   
  
• The obesity and inflammatory marker haptoglobin attracts monocytes via interaction with chemokine (C-C motif) receptor 2 (CCR2).
  Maffei M, Funicello M, Vottari T, Gamucci O, Costa M, Lisi S, Viegi A, Ciampi O, Bardi G, Vitti P, Pinchera A, Santini F
  BMC Biol. 2009
  PubMed ID: 20017911
   
  
• Capillary arterialization requires the bone-marrow-derived cell (BMC)-specific expression of chemokine (C-C motif) receptor-2, but BMCs do not transdifferentiate into microvascular smooth muscle.
  Nickerson MM, Burke CW, Meisner JK, Shuptrine CW, Song J, Price RJ
  Angiogenesis. 2009
  PubMed ID: 19777360
   
  
• Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosis.
  Nyquist PA, Winkler CA, McKenzie LM, Yanek LR, Becker LC, Becker DM
  Cerebrovasc Dis. 2009
  PubMed ID: 19506371
   
  
• Sequence variants of chemokine receptor genes and susceptibility to HIV-1 infection.
  Parczewski M, Leszczyszyn-Pynka M, Kaczmarczyk M, Adler G, Binczak-Kuleta A, Loniewska B, Boron-Kaczmarska A, Ciechanowicz A
  J Appl Genet. 2009
  PubMed ID: 19433914
   
  
• CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation.
  Camargo JF, Quinones MP, Mummidi S, Srinivas S, Gaitan AA, Begum K, Jimenez F, VanCompernolle S, Unutmaz D, Ahuja SS, Ahuja SK
  J Immunol. 2009
  PubMed ID: 19109148
   
  
• Impact of chemokine receptor CCR2 and CCR5 gene polymorphism on allograft outcome in North Indian renal transplant recipients.
  Singh R, Kapoor R, Srivastava A, Mittal RD
  Scand J Immunol. 2009
  PubMed ID: 19037908
   
  
• Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay.
  Greisenegger S, Zehetmayer S, Bauer P, Endler G, Ferrari J, Lang W, Janisiw M, Steiner L, Cheng S, Lalouschek W, Mannhalter C
  Clin Chem. 2009
  PubMed ID: 19028820
   
  
• Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone.
  Lu Y, Chen Q, Corey E, Xie W, Fan J, Mizokami A, Zhang J
  Clin Exp Metastasis. 2009
  PubMed ID: 19002595
   
  
• Monocyte chemotactic protein-1 (MCP-1), its receptor, and macrophages in the perifollicular stroma during the human ovulatory process.
  Dahm-Kähler P, Ghahremani M, Lind AK, Sundfeldt K, Brännström M
  Fertil Steril. 2009
  PubMed ID: 18829011
   
  
• Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells.
  Lorincz MT, Zawistowski VA
  Mol Cell Neurosci. 2009
  PubMed ID: 18625318
   
  
• Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue.
  Ito A, Suganami T, Yamauchi A, Degawa-Yamauchi M, Tanaka M, Kouyama R, Kobayashi Y, Nitta N, Yasuda K, Hirata Y, Kuziel WA, Takeya M, Kanegasaki S, Kamei Y, Ogawa Y
  J Biol Chem. 2008
  PubMed ID: 18977759
   
  
• Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection.
  Bierly AL, Shufesky WJ, Sukhumavasi W, Morelli AE, Denkers EY
  J Immunol. 2008
  PubMed ID: 19050266
   
  
• Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction.
  Rafei M, Hsieh J, Fortier S, Li M, Yuan S, Birman E, Forner K, Boivin MN, Doody K, Tremblay M, Annabi B, Galipeau J
  Blood. 2008
  PubMed ID: 18812467
   
  
• Anti-inflammatory effects of an inflammatory chemokine: CCL2 inhibits lymphocyte homing by modulation of CCL21-triggered integrin-mediated adhesions.
  Flaishon L, Hart G, Zelman E, Moussion C, Grabovsky V, Lapidot Tal G, Feigelson S, Margalit R, Harmelin A, Avin-Wittenberg T, Shoseyov D, Alon R, Girard JP, Shachar I
  Blood. 2008
  PubMed ID: 18802011
   
  
• Distribution of HIV-1 resistant polymorphisms among HIV infected patients in Georgia.
  Karchava M, Nelson KE, Gochitashvili N, Dvali N, Tsertsvadze T
  Georgian Med News. 2008
  PubMed ID: 19124913
   
  
• Association of CCR5-59029 A/G and CCR2-V64I variants with renal allograft survival.
  Omrani MD, Mokhtari MR, Tagizadae A, Bagheri M, Ahmad-Poor P
  Iran J Immunol. 2008
  PubMed ID: 19098363
   
  
• Association and preferential transmission of the CCR2V64I polymorphism with absence of asthma in high-risk families.
  Al-Abdulhadi SA, Al-Rabia MW
  Saudi Med J. 2008
  PubMed ID: 19082218
   
  
• MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.
  Sheahan T, Morrison TE, Funkhouser W, Uematsu S, Akira S, Baric RS, Heise MT
  PLoS Pathog. 2008
  PubMed ID: 19079579
   
  
• No association between common chemokine and chemokine receptor gene variants and prostate cancer risk.
  Petersen DC, Severi G, Hoang HN, Padilla EJ, Southey MC, English DR, Hopper JL, Giles GG, Hayes VM
  Cancer Epidemiol Biomarkers Prev. 2008
  PubMed ID: 19064579
   
  
• Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
  Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
  J Immunol. 2008
  PubMed ID: 19017998
   
  
• The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia-reperfusion injury.
  Li L, Huang L, Sung SS, Vergis AL, Rosin DL, Rose CE, Lobo PI, Okusa MD
  Kidney Int. 2008
  PubMed ID: 18843253
   
  
• Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes.
  Lumeng CN, DelProposto JB, Westcott DJ, Saltiel AR
  Diabetes. 2008
  PubMed ID: 18829989
   
  
• Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury.
  Holt MP, Cheng L, Ju C
  J Leukoc Biol. 2008
  PubMed ID: 18713872
   
  
• Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium.
  Kim JW, Kang KH, Burrola P, Mak TW, Lemke G
  Genes Dev. 2008
  PubMed ID: 18997061
   
  
• Distribution of CCR5-Delta32, CCR2-64I, SDF1-3'A, CX3CR1-249I, and CX3CR1-280M in Chinese populations.
  Qian Y, Sun H, Lin K, Shi L, Shi L, Chu J
  AIDS Res Hum Retroviruses. 2008
  PubMed ID: 19032065
   
  
• Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells.
  Kang SJ, Liang HE, Reizis B, Locksley RM
  Immunity. 2008
  PubMed ID: 19006696
   
  
• Contribution of TNF-308A and CCL2-2518A to carotid intima-media thickness in obese mexican children and adolescents.
  González-Enríquez GV, Rubio-Benítez MI, García-Gallegos V, Portilla-de Buen E, Troyo-Sanromán R, Leal-Cortés CA
  Arch Med Res. 2008
  PubMed ID: 18996288
   
  
• Signaling through MyD88 regulates leukocyte recruitment after brain injury.
  Babcock AA, Toft-Hansen H, Owens T
  J Immunol. 2008
  PubMed ID: 18941239
   
  
• Tuberculosis triggers a tissue-dependent program of differentiation and acquisition of effector functions by circulating monocytes.
  Sköld M, Behar SM
  J Immunol. 2008
  PubMed ID: 18941226
   
  
• Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation.
  Favre N, Camps M, Arod C, Chabert C, Rommel C, Pasquali C
  Proteomics. 2008
  PubMed ID: 18846510
   
  
• Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals.
  Singh KK, Hughes MD, Chen J, Phiri K, Rousseau C, Kuhn L, Coutsoudis A, Jackson JB, Guay LA, Musoke P, Mmiro F, Semba RD, Spector SA
  J Acquir Immune Defic Syndr. 2008
  PubMed ID: 18845960
   
  
• Photoreceptor protection after photodynamic therapy using dexamethasone in a rat model of choroidal neovascularization.
  She H, Nakazawa T, Matsubara A, Connolly E, Hisatomi T, Noda K, Kim I, Gragoudas ES, Miller JW
  Invest Ophthalmol Vis Sci. 2008
  PubMed ID: 18421085
   
  
• Prevalence in the United States of Selected Candidate Gene Variants: Third National Health and Nutrition Examination Survey, 1991-1994.
  Chang MH, Lindegren ML, Butler MA, Chanock SJ, Dowling NF, Gallagher M, Moonesinghe R, Moore CA, Ned RM, Reichler MR, Sanders CL, Welch R, Yesupriya A, Khoury MJ, for the CDC/NCI NHANES III Genomics Working Group
  Am J Epidemiol. 2008
  PubMed ID: 18936436
   
  
• SDF1-3'A Gene Mutation Is Correlated with Increased Susceptibility to HIV Type 1 Infection by Sexual Transmission in Han Chinese.
  Wang Y, Wang X, Peng J, Chen L, Cheng J, Nie S, Feng T, Zhao G, Zhao J, Shi X
  AIDS Res Hum Retroviruses. 2008
  PubMed ID: 18928397
   
  
• CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection.
  Engel DR, Maurer J, Tittel AP, Weisheit C, Cavlar T, Schumak B, Limmer A, van Rooijen N, Trautwein C, Tacke F, Kurts C
  J Immunol. 2008
  PubMed ID: 18832716
   
  
• Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
  Hosgood HD, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q
  Carcinogenesis. 2008
  PubMed ID: 18676680
   
  
• Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
  Habermann TM, Wang SS, Maurer MJ, Morton LM, Lynch CF, Ansell SM, Hartge P, Severson RK, Rothman N, Davis S, Geyer SM, Cozen W, Chanock SJ, Cerhan JR
  Blood. 2008
  PubMed ID: 18633131
   
  
• Evidence for PI-3K-dependent migration of Th17-polarized cells in response to CCR2 and CCR6 agonists.
  Webb A, Johnson A, Fortunato M, Platt A, Crabbe T, Christie MI, Watt GF, Ward SG, Jopling LA
  J Leukoc Biol. 2008
  PubMed ID: 18586982
   
  
• Better CD4+ T cell recovery in Brazilian HIV-infected individuals under HAART due to cumulative carriage of SDF-1-3'A, CCR2-V64I, CCR5-D32 and CCR5-promoter 59029A/G polymorphisms.
  Rigato PO, Hong MA, Casseb J, Ueda M, de Castro I, Benard G, Duarte AJ
  Curr HIV Res. 2008
  PubMed ID: 18855658
   
  
• CCR2 receptor is essential to activate microbicidal mechanisms to control Toxoplasma gondii infection in the central nervous system.
  Benevides L, Milanezi CM, Yamauchi LM, Benjamim CF, Silva JS, Silva NM
  Am J Pathol. 2008
  PubMed ID: 18688032
   
  
• MCP-1/CCR2 system is involved in high glucose-induced fibronectin and type IV collagen expression in cultured mesangial cells.
  Park J, Ryu DR, Li JJ, Jung DS, Kwak SJ, Lee SH, Yoo TH, Han SH, Lee JE, Kim DK, Moon SJ, Kim K, Han DS, Kang SW
  Am J Physiol Renal Physiol. 2008
  PubMed ID: 18579703
   
  
• Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion.
  Capoccia BJ, Gregory AD, Link DC
  J Leukoc Biol. 2008
  PubMed ID: 18550788
   
  
• Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body.
  Lam SY, Tipoe GL, Liong EC, Fung ML
  Histochem Cell Biol. 2008
  PubMed ID: 18446360
   
  
• Ly-6G+CCR2- myeloid cells rather than Ly-6ChighCCR2+ monocytes are required for the control of bacterial infection in the central nervous system.
  Mildner A, Djukic M, Garbe D, Wellmer A, Kuziel WA, Mack M, Nau R, Prinz M
  J Immunol. 2008
  PubMed ID: 18684962
   
  
• Neutrophil secretion products pave the way for inflammatory monocytes.
  Soehnlein O, Zernecke A, Eriksson EE, Rothfuchs AG, Pham CT, Herwald H, Bidzhekov K, Rottenberg ME, Weber C, Lindbom L
  Blood. 2008
  PubMed ID: 18490516
   
  
• The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells.
  Cho J, Gruol DL
  J Neuroimmunol. 2008
  PubMed ID: 18584881
   
  
• Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii.
  Dunay IR, Damatta RA, Fux B, Presti R, Greco S, Colonna M, Sibley LD
  Immunity. 2008
  PubMed ID: 18691912
   
  
• Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues.
  Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM
  Blood. 2008
  PubMed ID: 18347198
   
  
• A polymorphism in the CCL2 chemokine gene is associated with asthma risk: a case-control and a family study in Tunisia.
  Chelbi H, Ghadiri A, Lacheb J, Ghandil P, Hamzaoui K, Hamzaoui A, Combadiere C
  Genes Immun. 2008
  PubMed ID: 18615095
   
  
• CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans.
  Osterholzer JJ, Curtis JL, Polak T, Ames T, Chen GH, McDonald R, Huffnagle GB, Toews GB
  J Immunol. 2008
  PubMed ID: 18566428
   
  
• Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist-treated rats.
  Dansereau MA, Gosselin RD, Pohl M, Pommier B, Mechighel P, Mauborgne A, Rostene W, Kitabgi P, Beaudet N, Sarret P, Melik-Parsadaniantz S
  J Neurochem. 2008
  PubMed ID: 18419759
   
  
• Further evidence for a crucial role of resident endoneurial macrophages in peripheral nerve disorders: lessons from acrylamide-induced neuropathy.
  Müller M, Wacker K, Getts D, Ringelstein EB, Kiefer R
  Glia. 2008
  PubMed ID: 18383339
   
  
• Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.
  Luttrell LM
  Mol Biotechnol. 2008
  PubMed ID: 18240029
   
  
• Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice.
  Sawanobori Y, Ueha S, Kurachi M, Shimaoka T, Talmadge JE, Abe J, Shono Y, Kitabatake M, Kakimi K, Mukaida N, Matsushima K
  Blood. 2008
  PubMed ID: 18375791
   
  
• Glycated LDL increases monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated chemotaxis.
  Isoda K, Folco E, Marwali MR, Ohsuzu F, Libby P
  Atherosclerosis. 2008
  PubMed ID: 18164016
   
  
• The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals.
  Rittig K, Peter A, Baltz KM, Tschritter O, Weigert C, Andreozzi F, Perticone F, Siegel-Axel DI, Stefan N, Fritsche A, Salih HR, Schleicher E, Machicao F, Sesti G, Häring HU, Balletshofer BM
  Atherosclerosis. 2008
  PubMed ID: 18096169
   
  
• A common haplotype of the C-C chemokine receptor 2 gene and HLA-DRB1*0301 are independent genetic risk factors for Löfgren's syndrome.
  Spagnolo P, Sato H, Grunewald J, Brynedal B, Hillert J, Mañá J, Wells AU, Eklund A, Welsh KI, du Bois RM
  J Intern Med. 2008
  PubMed ID: 18513341
   
  
• Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.
  Jia T, Serbina NV, Brandl K, Zhong MX, Leiner IM, Charo IF, Pamer EG
  J Immunol. 2008
  PubMed ID: 18453605
   
  
• Force-dependent development of neuropathic central pain and time-related CCL2/CCR2 expression after graded spinal cord contusion injuries of the rat.
  Knerlich-Lukoschus F, Juraschek M, Blömer U, Lucius R, Mehdorn HM, Held-Feindt J
  J Neurotrauma. 2008
  PubMed ID: 18338959
   
  
• Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo.
  Alder JK, Georgantas RW, Hildreth RL, Kaplan IM, Morisot S, Yu X, McDevitt M, Civin CI
  J Immunol. 2008
  PubMed ID: 18390749
   
  
• Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury.
  Horiguchi N, Wang L, Mukhopadhyay P, Park O, Jeong WI, Lafdil F, Osei-Hyiaman D, Moh A, Fu XY, Pacher P, Kunos G, Gao B
  Gastroenterology. 2008
  PubMed ID: 18395093
   
  
• Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response.
  Pahler JC, Tazzyman S, Erez N, Chen YY, Murdoch C, Nozawa H, Lewis CE, Hanahan D
  Neoplasia. 2008
  PubMed ID: 18392134
   
  
• Essential role of C/EBPalpha in G-CSF-induced transcriptional activation and chromatin modification of myeloid-specific genes.
  Iida S, Watanabe-Fukunaga R, Nagata S, Fukunaga R
  Genes Cells. 2008
  PubMed ID: 18363963
   
  
• Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus.
  McMillan TR, Moore BB, Weinberg JB, Vannella KM, Fields WB, Christensen PJ, van Dyk LF, Toews GB
  Am J Respir Crit Care Med. 2008
  PubMed ID: 18187693
   
  
• Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis.
  Saederup N, Chan L, Lira SA, Charo IF
  Circulation. 2008
  PubMed ID: 18165355
   
  
• Host Genetic Influences on Highly Active Antiretroviral Therapy Efficacy and AIDS-Free Survival.
  Hendrickson SL, Jacobson LP, Nelson GW, Phair JP, Lautenberger J, Johnson RC, Kingsley L, Margolick JB, Detels R, Goedert JJ, O'Brien SJ
  J Acquir Immune Defic Syndr. 2008
  PubMed ID: 18391751
   
  
• [Distribution of HIV/AIDS associated CCR2-64allele of 14 Chinese ethnic populations in South China.]
  Qian Y, Lin KQ, Shi L, Shi L, Chu JY
  Yi Chuan. 2008
  PubMed ID: 18332000
   
  
• Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations.
  Jakubzick C, Tacke F, Ginhoux F, Wagers AJ, van Rooijen N, Mack M, Merad M, Randolph GJ
  J Immunol. 2008
  PubMed ID: 18292524
   
  
• Transcellular transport of CCL2 across brain microvascular endothelial cells.
  Ge S, Song L, Serwanski DR, Kuziel WA, Pachter JS
  J Neurochem. 2008
  PubMed ID: 18289346
   
  
• Effects of CCR2 and CCRS polymorphisms on HIV-1 infection in Thai females.
  Wichukchinda N, Nakayama EE, Rojanawiwat A, Pathipvanich P, Auwanit W, Vongsheree S, Ariyoshi K, Sawanpanyalert P, Shioda T
  J Acquir Immune Defic Syndr. 2008
  PubMed ID: 18197127
   
  
• CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality.
  Lin KL, Suzuki Y, Nakano H, Ramsburg E, Gunn MD
  J Immunol. 2008
  PubMed ID: 18250467
   
  
• Association of MCP-1 and CCR2 polymorphisms with the risk of late acute rejection after renal transplantation in Korean patients.
  Kang SW, Park SJ, Kim YW, Kim YH, Sohn HS, Yoon YC, Joo H, Jeong KH, Lee SH, Lee TW, Ihm CG
  Int J Immunogenet. 2008
  PubMed ID: 18186797
   
  
• COX-2 and CCR2 induced by CD40 ligand and MCP-1 are linked to VEGF production in endothelial cells.
  Futagami S, Hiratsuka T, Shindo T, Hamamoto T, Tatsuguchi A, Nobue U, Shinji Y, Suzuki K, Kusunoki M, Tanaka S, Wada K, Miyake K, Gudis K, Tsukui T, Sakamoto C
  Prostaglandins Leukot Essent Fatty Acids. 2008
  PubMed ID: 18093816
   
  
• Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.
  Atik B, Skwor TA, Kandel RP, Sharma B, Adhikari HK, Steiner L, Erlich H, Dean D
  PLoS ONE. 2008
  PubMed ID: 18974840
   
  
• Dissociation of heterotrimeric g proteins in cells.
  Lambert NA
  Sci Signal. 2008
  PubMed ID: 18577758
   
  
• Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model.
  Alexis JD, Pyo RT, Chereshnev I, Katz J, Rollins BJ, Charo IF, Taubman MB
  J Vasc Res. 2008
  PubMed ID: 18463419
   
  
• RANTES-403 polymorphism is associated with reduced risk of gastric cancer in women.
  Liou JM, Lin JT, Huang SP, Wu CY, Wang HP, Lee YC, Chiu HM, Shun CT, Lin MT, Wu MS
  J Gastroenterol. 2008
  PubMed ID: 18306985
   
  
• Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration.
  Despriet DD, Bergen AA, Merriam JE, Zernant J, Barile GR, Smith RT, Barbazetto IA, van Soest S, Bakker A, de Jong PT, Allikmets R, Klaver CC
  Invest Ophthalmol Vis Sci. 2008
  PubMed ID: 18172114
   
  
• Genetic control of chemokines in severe human internal carotid artery stenosis.
  Ghilardi G, Biondi ML, Turri O, Pateri F, d'Eril GM, Scorza R
  Cytokine. 2008
  PubMed ID: 18060801
   
  
• Involvement of CC chemokines in gammadelta T lymphocyte trafficking during allergic inflammation: the role of CCL2/CCR2 pathway.
  Penido C, Costa MF, Souza MC, Costa KA, Candéa AL, Benjamim CF, Henriques MG
  Int Immunol. 2008
  PubMed ID: 18056919
   
  
• Activation of the nuclear factor of activated T-cells (NFAT) mediates upregulation of CCR2 chemokine receptors in dorsal root ganglion (DRG) neurons: a possible mechanism for activity-dependent transcription in DRG neurons in association with neuropathic
  Jung H, Miller RJ
  Mol Cell Neurosci. 2008
  PubMed ID: 17949992
   
  
• Role of astrocytes and chemokine systems in acute TNFalpha induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-kappaB and Akt.
  Quinones MP, Kalkonde Y, Estrada CA, Jimenez F, Ramirez R, Mahimainathan L, Mummidi S, Choudhury GG, Martinez H, Adams L, Mack M, Reddick RL, Maffi S, Haralambous S, Probert L, Ahuja SK, Ahuja SS
  Mol Cell Neurosci. 2008
  PubMed ID: 17949991
   
  
• CC chemokine receptor-2A is frequently overexpressed in glioblastoma.
  Liang Y, Bollen AW, Gupta N
  J Neurooncol. 2008
  PubMed ID: 17703277
   
  
• Analysis of CCR5, CCR2, SDF1 and RANTES gene polymorphisms in subjects with HIV-related PML and not determined leukoencephalopathy.
  Guerini FR, Delbue S, Zanzottera M, Agliardi C, Saresella M, Mancuso R, Maserati R, Marchioni E, Gori A, Ferrante P
  Biomed Pharmacother. 2008
  PubMed ID: 17560067
   
  
• Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state.
  Ginhoux F, Collin MP, Bogunovic M, Abel M, Leboeuf M, Helft J, Ochando J, Kissenpfennig A, Malissen B, Grisotto M, Snoeck H, Randolph G, Merad M
  J Exp Med. 2007
  PubMed ID: 18086862
   
  
• Monocyte chemoattractant protein-1/CC chemokine ligand 2 controls microtubule-driven biogenesis and leukotriene B4-synthesizing function of macrophage lipid bodies elicited by innate immune response.
  Pacheco P, Vieira-de-Abreu A, Gomes RN, Barbosa-Lima G, Wermelinger LB, Maya-Monteiro CM, Silva AR, Bozza MT, Castro-Faria-Neto HC, Bandeira-Melo C, Bozza PT
  J Immunol. 2007
  PubMed ID: 18056397
   
  
• The monocyte chemoattractant protein-1/cognate CC chemokine receptor 2 system affects cell motility in cultured human podocytes.
  Burt D, Salvidio G, Tarabra E, Barutta F, Pinach S, Dentelli P, Camussi G, Perin PC, Gruden G
  Am J Pathol. 2007
  PubMed ID: 18055544
   
  
• Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions.
  Mildner A, Schmidt H, Nitsche M, Merkler D, Hanisch UK, Mack M, Heikenwalder M, Brück W, Priller J, Prinz M
  Nat Neurosci. 2007
  PubMed ID: 18026096
   
  
• Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: the NHLBI family heart study follow-up examination.
  Bielinski SJ, Pankow JS, Miller MB, Hopkins PN, Eckfeldt JH, Hixson J, Liu Y, Register T, Myers RH, Arnett DK
  Genes Immun. 2007
  PubMed ID: 17917677
   
  
• Variants of chemokine receptor 2 and interleukin 4 receptor, but not interleukin 10 or Fas ligand, increase risk of cervical cancer.
  Ivansson EL, Gustavsson IM, Magnusson JJ, Steiner LL, Magnusson PK, Erlich HA, Gyllensten UB
  Int J Cancer. 2007
  PubMed ID: 17688234
   
  
• Analysis of multiple SNPs in genetic association studies: comparison of three multi-locus methods to prioritize and select SNPs.
  Heidema AG, Feskens EJ, Doevendans PA, Ruven HJ, van Houwelingen HC, Mariman EC, Boer JM
  Genet Epidemiol. 2007
  PubMed ID: 17615573
   
  
• The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
  Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ
  J Exp Med. 2007
  PubMed ID: 18025128
   
  
• Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain.
  Zhang J, Shi XQ, Echeverry S, Mogil JS, De Koninck Y, Rivest S
  J Neurosci. 2007
  PubMed ID: 17989304
   
  
• [Expression of chemokine receptor CCR2 in cerebral tissue of newborn rat with experimental hypoxic-ischemic brain damage]
  Feng X, Yao YJ
  Sichuan Da Xue Xue Bao Yi Xue Ban. 2007
  PubMed ID: 18095591
   
  
• Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes.
  Cullen JP, Morrow D, Jin Y, von Offenberg Sweeney N, Sitzmann JV, Cahill PA, Redmond EM
  Atherosclerosis. 2007
  PubMed ID: 17499741
   
  
• Genetic variability of major inflammatory mediators has no impact on the outcome of kidney transplantation.
  Brabcova I, Petrasek J, Hribova P, Hyklova K, Bartosova K, Lacha J, Viklický O
  Transplantation. 2007
  PubMed ID: 17989610
   
  
• Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers.
  Sohy D, Parmentier M, Springael JY
  J Biol Chem. 2007
  PubMed ID: 17715128
   
  
• Polymorphisms in CCR5 chemokine receptor gene in Japan.
  Liu H, Nakayama EE, Theodorou I, Nagai Y, Likanonsakul S, Wasi C, Debre P, Iwamoto A, Shioda T
  Int J Immunogenet. 2007
  PubMed ID: 17845302
   
  
• Regulation of C-C motif chemokine ligand 2 and its receptor in human decidual stromal cells by pregnancy-associated hormones in early gestation.
  He YY, Du MR, Guo PF, He XJ, Zhou WH, Zhu XY, Li DJ
  Hum Reprod. 2007
  PubMed ID: 17704101
   
  
• Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease.
  Breunis WB, Biezeveld MH, Geissler J, Kuipers IM, Lam J, Ottenkamp J, Hutchinson A, Welch R, Chanock SJ, Kuijpers TW
  Clin Exp Immunol. 2007
  PubMed ID: 17672867
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
  Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B
  J Infect Dis. 2007
  PubMed ID: 17703412
   
  
• Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy.
  Kanamori H, Matsubara T, Mima A, Sumi E, Nagai K, Takahashi T, Abe H, Iehara N, Fukatsu A, Okamoto H, Kita T, Doi T, Arai H
  Biochem Biophys Res Commun. 2007
  PubMed ID: 17631861
   
  
• Expression of CCR2A, an isoform of MCP-1 receptor, is increased by MCP-1, CD40 ligand and TGF-beta in fibroblast like synoviocytes of patients with RA.
  Cho ML, Yoon BY, Ju JH, Jung YO, Jhun JY, Park MK, Park SH, Cho CS, Kim HY
  Exp Mol Med. 2007
  PubMed ID: 17934338
   
  
• Deletion of CCR2 but not CCR5 or CXCR3 inhibits aortic aneurysm formation.
  MacTaggart JN, Xiong W, Knispel R, Baxter BT
  Surgery. 2007
  PubMed ID: 17689697
   
  
• Delayed angiogenesis and VEGF production in CCR2-/- mice during impaired skeletal muscle regeneration.
  Ochoa O, Sun D, Reyes-Reyna SM, Waite LL, Michalek JE, McManus LM, Shireman PK
  Am J Physiol Regul Integr Comp Physiol. 2007
  PubMed ID: 17522124
   
  
• CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers.
  Huang B, Lei Z, Zhao J, Gong W, Liu J, Chen Z, Liu Y, Li D, Yuan Y, Zhang GM, Feng ZH
  Cancer Lett. 2007
  PubMed ID: 17257744
   
  
• Determination of the sites of tyrosine O-sulfation in peptides and proteins.
  Yu Y, Hoffhines AJ, Moore KL, Leary JA
  Nat Methods. 2007
  PubMed ID: 17558413
   
  
• Association of CCR2 polymorphisms with the number of closed coronary artery vessels in coronary artery disease.
  Cha SH, Lee JK, Lee JY, Kim HT, Ryu HJ, Han BG, Kim JW, Oh B, Kimm K, Shin HD, Park BL, Park S, Park HY, Jang Y
  Clin Chim Acta. 2007
  PubMed ID: 17482150
   
  
• Analysis of CC chemokine receptor 5 and 2 polymorphisms and renal transplant survival.
  Yigit B, Bozkurt N, Berber I, Titiz I, Isbir T
  Cell Biochem Funct. 2007
  PubMed ID: 16598837
   
  
• CCR4-dependent regulatory T cell function in inflammatory bowel disease.
  Yuan Q, Bromley SK, Means TK, Jones KJ, Hayashi F, Bhan AK, Luster AD
  J Exp Med. 2007
  PubMed ID: 17548518
   
  
• [Association between sequence variation of Env, Gag genes from the same source and IV-1 disease progression and host genetic polymorphism]
  Bai LS, Wang KL, Zhou GE, Meng B, Liu YC, Zeng Y
  Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2007
  PubMed ID: 17653321
   
  
• CCR2b-64I allelic polymorphisms in advanced HIV-infected Koreans accelerate disease progression.
  Choi BS, Choi JH, Kim SS, Kee MK, Lee JS
  AIDS Res Hum Retroviruses. 2007
  PubMed ID: 17604544
   
  
• RANTES, MCP-1, CCR2, CCR5, CXCR1 and CXCR4 gene polymorphisms are not associated with the outcome of hepatitis B virus infection: results from a large scale single ethnic population.
  Cheong JY, Cho SW, Choi JY, Lee JA, Kim MH, Lee JE, Hahm KB, Kim JH
  J Korean Med Sci. 2007
  PubMed ID: 17596666
   
  
• Distribution of CCR2 polymorphism in HIV-1-infected and healthy subjects in North India.
  Kaur G, Singh P, Kumar N, Rapthap CC, Sharma G, Vajpayee M, Wig N, Sharma SK, Mehra NK
  Int J Immunogenet. 2007
  PubMed ID: 17504503
   
  
• CCR2 expression correlates with prostate cancer progression.
  Lu Y, Cai Z, Xiao G, Liu Y, Keller ET, Yao Z, Zhang J
  J Cell Biochem. 2007
  PubMed ID: 17216598
   
  
• Microglial recruitment, activation, and proliferation in response to primary demyelination.
  Remington LT, Babcock AA, Zehntner SP, Owens T
  Am J Pathol. 2007
  PubMed ID: 17456776
   
  
• Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis.
  Winter C, Taut K, Srivastava M, Länger F, Mack M, Briles DE, Paton JC, Maus R, Welte T, Gunn MD, Maus UA
  J Immunol. 2007
  PubMed ID: 17442967
   
  
• Lack of association of some chemokine system polymorphisms with the risks of death and hepatocellular carcinoma occurrence in patients with alcoholic cirrhosis: a prospective study.
  Nahon P, Sutton A, Rufat P, Faisant C, Simon C, Barget N, Trinchet JC, Beaugrand M, Gattegno L, Charnaux N
  Eur J Gastroenterol Hepatol. 2007
  PubMed ID: 17413295
   
  
• Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2.
  Ringe J, Strassburg S, Neumann K, Endres M, Notter M, Burmester GR, Kaps C, Sittinger M
  J Cell Biochem. 2007
  PubMed ID: 17295203
   
  
• p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells.
  Ko J, Yun CY, Lee JS, Kim JH, Kim IS
  Exp Mol Med. 2007
  PubMed ID: 17464174
   
  
• CCL2-2518 A/G and CCR2 190 A/G do not influence the outcome of hepatitis C virus infection in the Spanish population.
  Montes-Cano MA, Garcia-Lozano JR, Aguilar-Reina J, Romero-Gomez M, Barroso N, Nunez-Roldan A, Gonzalez-Escribano MF
  World J Gastroenterol. 2007
  PubMed ID: 17465499
   
  
• Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.
  Robays LJ, Maes T, Lebecque S, Lira SA, Kuziel WA, Brusselle GG, Joos GF, Vermaelen KV
  J Immunol. 2007
  PubMed ID: 17404315
   
  
• Characterization of the molecular clock in mouse peritoneal macrophages.
  Hayashi M, Shimba S, Tezuka M
  Biol Pharm Bull. 2007
  PubMed ID: 17409491
   
  
• CCL2-independent role of CCR2 in immune responses against Leishmania major.
  Quinones MP, Estrada CA, Jimenez F, Martinez H, Willmon O, Kuziel WA, Ahuja SK, Ahuja SS
  Parasite Immunol. 2007
  PubMed ID: 17371458
   
  
• Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites.
  Tsou CL, Peters W, Si Y, Slaymaker S, Aslanian AM, Weisberg SP, Mack M, Charo IF
  J Clin Invest. 2007
  PubMed ID: 17364026
   
  
• Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.
  El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, Luster AD
  Nat Med. 2007
  PubMed ID: 17351623
   
  
• Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice.
  Dimitrijevic OB, Stamatovic SM, Keep RF, Andjelkovic AV
  Stroke. 2007
  PubMed ID: 17332467
   
  
• A novel activator of C-C chemokine, FROUNT, is expressed with C-C chemokine receptor 2 and its ligand in failing human heart.
  Satoh M, Akatsu T, Ishkawa Y, Minami Y, Nakamura M
  J Card Fail. 2007
  PubMed ID: 17395051
   
  
• Deletion of the chemokine receptor CCR1 prolongs corneal allograft survival.
  Hamrah P, Yamagami S, Liu Y, Zhang Q, Vora SS, Lu B, Gerard CJ, Dana MR
  Invest Ophthalmol Vis Sci. 2007
  PubMed ID: 17325167
   
  
• Distribution of CCR5delta32, CCR2-64I and SDF1-3'A and plasma levels of SDF-1 in HIV-1 seronegative North Indians.
  Verma R, Gupta RB, Singh K, Bhasin R, Anand Shukla A, Chauhan SS, Luthra K
  J Clin Virol. 2007
  PubMed ID: 17240189
   
  
• Chemokine regulation of the inflammatory response to a low-dose influenza infection in CCR2-/- mice.
  Wareing MD, Lyon A, Inglis C, Giannoni F, Charo I, Sarawar SR
  J Leukoc Biol. 2007
  PubMed ID: 17179466
   
  
• Association between a genetic variation of CC chemokine receptor-2 and atopic asthma.
  Kim YK, Oh HB, Lee EY, Gho YS, Lee JE, Kim YY
  Allergy. 2007
  PubMed ID: 17298432
   
  
• Recruitment of macrophages and polymorphonuclear leukocytes in L:yme carditis.
  Montgomery RR, Booth CJ, Wang X, Blaho VA, Malawista SE, Brown CR
  Infect Immun. 2007
  PubMed ID: 17101663
   
  
• Effect of genetic variants of CCR2 and CCL2 on the natural history of HIV-1 infection: CCL2-2518GG is overrepresented in a cohort of Spanish HIV-1-infected subjects.
  Viladés C, Broch M, Plana M, Domingo P, Alonso-Villaverde C, Pedrol E, Knobel H, Dalmau D, Peraire J, Gutiérrez C, López A, Sambeat MA, Olona M, Garcia F, Richart C, Gatell JM, Vidal F, Chemokines and Long-Term Nonprogressors Study Group
  J Acquir Immune Defic Syndr. 2007
  PubMed ID: 17091019
   
  
• Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2-/- mice following ischemic injury.
  Contreras-Shannon V, Ochoa O, Reyes-Reyna SM, Sun D, Michalek JE, Kuziel WA, McManus LM, Shireman PK
  Am J Physiol Cell Physiol. 2007
  PubMed ID: 17020936
   
  
• Chemokines in the MPTP model of Parkinson's disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration.
  Kalkonde YV, Morgan WW, Sigala J, Maffi SK, Condello C, Kuziel W, Ahuja SS, Ahuja SK
  Brain Res. 2007
  PubMed ID: 17126305
   
  
• Generation, characterization and biological activity of CCL2 (MCP-1/JE) and CCL12 (MCP-5) specific antibodies.
  Tsui P, Das A, Whitaker B, Tornetta M, Stowell N, Kesavan P, Kaiser E, Lacy ER, Yan L, Snyder LA, Sweet R
  Hum Antibodies. 2007
  PubMed ID: 18334747
   
  
• Complementary DNA microarray analysis of chemokines and their receptors in allergic rhinitis.
  Zhang RX, Yu SQ, Jiang JZ, Liu GJ
  J Investig Allergol Clin Immunol. 2007
  PubMed ID: 17982926
   
  
• CCR5 haplotypes and mother-to-child HIV transmission in Malawi.
  Pedersen BR, Kamwendo D, Blood M, Mwapasa V, Molyneux M, North K, Rogerson SJ, Zimmerman P, Meshnick SR
  PLoS ONE. 2007
  PubMed ID: 17786209
   
  
• The influence of chemokine receptor CCR2 genotypes in the route to cervical carcinogenesis.
  Coelho A, Matos A, Catarino R, Pinto D, Sousa H, Pereira D, Medeiros R
  Gynecol Obstet Invest. 2007
  PubMed ID: 17664883
   
  
• Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE.
  Eltayeb S, Berg AL, Lassmann H, Wallström E, Nilsson M, Olsson T, Ericsson-Dahlstrand A, Sunnemark D
  J Neuroinflammation. 2007
  PubMed ID: 17484785
   
  
• Association of TGFbeta1, TNFalpha, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians.
  Prasad P, Tiwari AK, Kumar KM, Ammini AC, Gupta A, Gupta R, Thelma BK
  BMC Med Genet. 2007
  PubMed ID: 17428349
   
  
• Polymorphisms of chemokine and chemokine receptor genes in idiopathic immune-mediated posterior segment uveitis.
  Ahad MA, Missotten T, Abdallah A, Lympany PA, Lightman S
  Mol Vis. 2007
  PubMed ID: 17417600
   
  
• Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.
  Huang HY, Thuita L, Strickland P, Hoffman SC, Comstock GW, Helzlsouer KJ
  BMC Genet. 2007
  PubMed ID: 17355643
   
  
• Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata.
  Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ
  J Clin Invest. 2007
  PubMed ID: 17200719
   
  
• Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.
  Tacke F, Alvarez D, Kaplan TJ, Jakubzick C, Spanbroek R, Llodra J, Garin A, Liu J, Mack M, van Rooijen N, Lira SA, Habenicht AJ, Randolph GJ
  J Clin Invest. 2007
  PubMed ID: 17200718
   
  
• Obesity induces a phenotypic switch in adipose tissue macrophage polarization.
  Lumeng CN, Bodzin JL, Saltiel AR
  J Clin Invest. 2007
  PubMed ID: 17200717
   
  
• Genotypes and haplotypes of CCR2 and CCR3 genes in Japanese cedar pollinosis.
  Nakamura H, Higashikawa F, Nobukuni Y, Miyagawa K, Endo T, Imai T, Hatta K, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Ogino K, Akimaru K, Eboshida A
  Int Arch Allergy Immunol. 2007
  PubMed ID: 17135764
   
  
• Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery disease.
  Apostolakis S, Baritaki S, Kochiadakis GE, Igoumenidis NE, Panutsopulos D, Spandidos DA
  Thromb Res. 2007
  PubMed ID: 16480760
   
  
• MCP-1/CCR2 signalling pathway regulates hyperoxia-induced acute lung injury via nitric oxide production.
  Okuma T, Terasaki Y, Sakashita N, Kaikita K, Kobayashi H, Hayasaki T, Kuziel WA, Baba H, Takeya M
  Int J Exp Pathol. 2006
  PubMed ID: 17222215
   
  
• Polymorphisms in CCL2&CCL5 chemokines/chemokine receptors genes and their association with diseases.
  Navratilova Z
  Biomed Pap Med Fac Univ Palacky Olomouc Czech Repu. 2006
  PubMed ID: 17426779
   
  
• Tumor necrosis factor alpha- and inducible nitric oxide synthase-producing dendritic cells are rapidly recruited to the bladder in urinary tract infection but are dispensable for bacterial clearance.
  Engel D, Dobrindt U, Tittel A, Peters P, Maurer J, Gütgemann I, Kaissling B, Kuziel W, Jung S, Kurts C
  Infect Immun. 2006
  PubMed ID: 16966414
   
  
• The expression of monocyte chemoattractant protein-1 and C-C chemokine receptor 2 in post-kidney transplant patients and the influence of simvastatin treatment.
  Wang J, Zou H, Li Q, Wang Y, Xu Q
  Clin Chim Acta. 2006
  PubMed ID: 16781696
   
  
• Blood pressure regulation by CCR genes.
  Mettimano M, Specchia ML, La Torre G, Bruno A, Ricciardi G, Savi L, Romano-Spica V
  Clin Exp Hypertens. 2006
  PubMed ID: 17060059
   
  
• Examination of genetic effects of polymorphisms in the MCP-1 and CCR2 genes on MI in the Icelandic population.
  Bjarnadottir K, Eiriksdottir G, Aspelund T, Gudnason V
  Atherosclerosis. 2006
  PubMed ID: 16356504
   
  
• Genetic polymorphism of chemokine receptors CCR2 and CCR5 in Swedish cervical cancer patients.
  Zheng B, Wiklund F, Gharizadeh B, Sadat M, Gambelunghe G, Hallmans G, Dillner J, Wallin KL, Ghaderi M
  Anticancer Res. 2006
  PubMed ID: 17094383
   
  
• Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
  Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
  J Immunol. 2006
  PubMed ID: 16920980
   
  
• Influence of a monocyte chemoattractant protein 1 mutated allele on the response to protease inhibitor-based antiretroviral therapy.
  Coll B, Alonso-Villaverde C, Parra S, Rabassa A, Martorell L, Joven J, Masana L
  HIV Med. 2006
  PubMed ID: 16903979
   
  
• Gene polymorphisms in CCR5, CCR2, CX3CR1, SDF-1 and RANTES in exposed but uninfected partners of HIV-1 infected individuals in North India.
  Suresh P, Wanchu A, Sachdeva RK, Bhatnagar A
  J Clin Immunol. 2006
  PubMed ID: 16865553
   
  
• CCR2 mediates increases in glial activation caused by exposure to HIV-1 Tat and opiates.
  El-Hage N, Wu G, Ambati J, Bruce-Keller AJ, Knapp PE, Hauser KF
  J Neuroimmunol. 2006
  PubMed ID: 16831471
   
  
• Oxidized lipid-driven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells through a peroxisome proliferator-activated receptor gamma-dependent pathway.
  Barlic J, Zhang Y, Foley JF, Murphy PM
  Circulation. 2006
  PubMed ID: 16908772
   
  
• CCL2 regulates angiogenesis via activation of Ets-1 transcription factor.
  Stamatovic SM, Keep RF, Mostarica-Stojkovic M, Andjelkovic AV
  J Immunol. 2006
  PubMed ID: 16888027
   
  
• Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection: impact of chemokines and adhesion molecules.
  Herold S, von Wulffen W, Steinmueller M, Pleschka S, Kuziel WA, Mack M, Srivastava M, Seeger W, Maus UA, Lohmeyer J
  J Immunol. 2006
  PubMed ID: 16849492
   
  
• Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis.
  Tanuma N, Sakuma H, Sasaki A, Matsumoto Y
  Acta Neuropathol. 2006
  PubMed ID: 16733654
   
  
• The role of CCL12 in the recruitment of fibrocytes and lung fibrosis.
  Moore BB, Murray L, Das A, Wilke CA, Herrygers AB, Toews GB
  Am J Respir Cell Mol Biol. 2006
  PubMed ID: 16543609
   
  
• Chemokine gene polymorphisms in idiopathic anterior uveitis.
  Yeo TK, Ahad MA, Kuo NW, Spagnolo P, Menezo V, Lympany P, Lightman S
  Cytokine. 2006
  PubMed ID: 16950632
   
  
• Increased expression levels of monocyte CCR2 and monocyte chemoattractant protein-1 in patients with diabetes mellitus.
  Mine S, Okada Y, Tanikawa T, Kawahara C, Tabata T, Tanaka Y
  Biochem Biophys Res Commun. 2006
  PubMed ID: 16631114
   
  
• Chemokine CC receptor 2 is important for acute control of cardiac parasitism but does not contribute to cardiac inflammation after infection with Trypanosoma cruzi.
  Hardison JL, Kuziel WA, Manning JE, Lane TE
  J Infect Dis. 2006
  PubMed ID: 16652288
   
  
• CC chemokine receptor (CCR)-2 prevents arthritis development following infection by Mycobacterium avium.
  Quinones MP, Jimenez F, Martinez H, Estrada CA, Willmon O, Dudley M, Kuziel WA, Melby PC, Reddick RL, Ahuja SK, Ahuja SS
  J Mol Med. 2006
  PubMed ID: 16520943
   
  
• Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction.
  Zhou L, Azfer A, Niu J, Graham S, Choudhury M, Adamski FM, Younce C, Binkley PF, Kolattukudy PE
  Circ Res. 2006
  PubMed ID: 16574901
   
  
• The multiple personalities of the chemokine receptor CCR7 in dendritic cells.
  Sánchez-Sánchez N, Riol-Blanco L, Rodríguez-Fernández JL
  J Immunol. 2006
  PubMed ID: 16621978
   
  
• Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women.
  Pai JK, Kraft P, Cannuscio CC, Manson JE, Rexrode KM, Albert CM, Hunter D, Rimm EB
  Atherosclerosis. 2006
  PubMed ID: 16055130
   
  
• The DNA sequence, annotation and analysis of human chromosome 3.
  Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA
  Nature. 2006
  PubMed ID: 16641997
   
  
• Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.
  Delogu A, Schebesta A, Sun Q, Aschenbrenner K, Perlot T, Busslinger M
  Immunity. 2006
  PubMed ID: 16546096
   
  
• CC chemokine receptor-2 deficiency attenuates oxidative stress and infarct size caused by myocardial ischemia-reperfusion in mice.
  Hayasaki T, Kaikita K, Okuma T, Yamamoto E, Kuziel WA, Ogawa H, Takeya M
  Circ J. 2006
  PubMed ID: 16501303
   
  
• Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2.
  Serbina NV, Pamer EG
  Nat Immunol. 2006
  PubMed ID: 16462739
   
  
• Langerhans cells arise from monocytes in vivo.
  Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, Merad M
  Nat Immunol. 2006
  PubMed ID: 16444257
   
  
• MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes.
  Sakai N, Wada T, Furuichi K, Shimizu K, Kokubo S, Hara A, Yamahana J, Okumura T, Matsushima K, Yokoyama H, Kaneko S
  J Leukoc Biol. 2006
  PubMed ID: 16415174
   
  
• Polymorphisms in chemokine and chemokine receptor genes and the development of coal workers' pneumoconiosis.
  Nadif R, Mintz M, Rivas-Fuentes S, Jedlicka A, Lavergne E, Rodero M, Kauffmann F, Combadière C, Kleeberger SR
  Cytokine. 2006
  PubMed ID: 16524739
   
  
• Analysis of CCR5, CCR2, CX3CR1, and SDF1 polymorphisms in HIV-positive treated patients: impact on response to HAART and on peripheral T lymphocyte counts.
  Puissant B, Roubinet F, Massip P, Sandres-Saune K, Apoil PA, Abbal M, Pasquier C, Izopet J, Blancher A
  AIDS Res Hum Retroviruses. 2006
  PubMed ID: 16478397
   
  
• CCR2 allele polymorphisms in 15 Chinese ethnic populations.
  Zhang XL, Zhang CY, Yu Y, Chen F, Li P, Fu SB
  Int J Immunogenet. 2006
  PubMed ID: 16426243
   
  
• Analysis of corneal inflammation induced by cauterisation in CCR2 and MCP-1 knockout mice.
  Oshima T, Sonoda KH, Tsutsumi-Miyahara C, Qiao H, Hisatomi T, Nakao S, Hamano S, Egashira K, Charo IF, Ishibashi T
  Br J Ophthalmol. 2006
  PubMed ID: 16424537
   
  
• Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization.
  Yang X, Lu P, Ishida Y, Kuziel WA, Fujii C, Mukaida N
  Int J Cancer. 2006
  PubMed ID: 16052523
   
  
• Effects of polymorphisms of chemokine receptors on neurodevelopment and the onset of encephalopathy in children with perinatal HIV-1 infection.
  Llorente A, Brouwers P, Thompson B, Cheng I, Macmillan C, Larussa P, Mofenson L, Blasini I, Chase C
  Appl Neuropsychol. 2006
  PubMed ID: 17361671
   
  
• Genetic variations in CC chemokine receptors and hypertension.
  Zhang M, Ardlie K, Wacholder S, Welch R, Chanock S, O'Brien TR
  Am J Hypertens. 2006
  PubMed ID: 16461193
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• CCR2 modulates inflammatory and metabolic effects of high-fat feeding.
  Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW
  J Clin Invest. 2006
  PubMed ID: 16341265
   
  
• Behavioral risk exposure and host genetics of susceptibility to HIV-1 infection.
  Shrestha S, Strathdee SA, Galai N, Oleksyk T, Fallin MD, Mehta S, Schaid D, Vlahov D, O'Brien SJ, Smith MW
  J Infect Dis. 2006
  PubMed ID: 16323127
   
  
• Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue.
  Reichel CA, Khandoga A, Anders HJ, Schlöndorff D, Luckow B, Krombach F
  J Leukoc Biol. 2006
  PubMed ID: 16275892
   
  
• Chemokine receptor CCR2 expression by systemic sclerosis fibroblasts: evidence for autocrine regulation of myofibroblast differentiation.
  Carulli MT, Ong VH, Ponticos M, Shiwen X, Abraham DJ, Black CM, Denton CP
  Arthritis Rheum. 2005
  PubMed ID: 16320328
   
  
• Chemokine receptor expression in rat adjuvant-induced arthritis.
  Haas CS, Martinez RJ, Attia N, Haines GK, Campbell PL, Koch AE
  Arthritis Rheum. 2005
  PubMed ID: 16320322
   
  
• Polymorphisms of chemokine receptors and eNOS in Brazilian patients with sickle cell disease.
  Vargas AE, da Silva MA, Silla L, Chies JA
  Tissue Antigens. 2005
  PubMed ID: 16305685
   
  
• Distribution of HIV/AIDS protective SDF1, CCR5 and CCR2 gene variants within Cretan population.
  Apostolakis S, Baritaki S, Krambovitis E, Spandidos DA
  J Clin Virol. 2005
  PubMed ID: 16286055
   
  
• CCR2-64I and CXCL12 3'A alleles confer a favorable prognosis to AIDS patients undergoing HAART therapy.
  Passam AM, Zafiropoulos A, Miyakis S, Zagoreos I, Stavrianeas NG, Krambovitis E, Spandidos DA
  J Clin Virol. 2005
  PubMed ID: 16286054
   
  
• Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-prone mice.
  Pérez de Lema G, Maier H, Franz TJ, Escribese M, Chilla S, Segerer S, Camarasa N, Schmid H, Banas B, Kalaydjiev S, Busch DH, Pfeffer K, Mampaso F, Schlöndorff D, Luckow B
  J Am Soc Nephrol. 2005
  PubMed ID: 16267157
   
  
• Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol.
  Blednov YA, Bergeson SE, Walker D, Ferreira VM, Kuziel WA, Harris RA
  Behav Brain Res. 2005
  PubMed ID: 16105698
   
  
• Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy.
  Göser S, Ottl R, Brodner A, Dengler TJ, Torzewski J, Egashira K, Rose NR, Katus HA, Kaya Z
  Circulation. 2005
  PubMed ID: 16316965
   
  
• CCR5, RANTES and CX3CR1 polymorphisms: possible genetic links with acute heart rejection.
  Simeoni E, Vassalli G, Seydoux C, Ramsay D, Noll G, von Segesser LK, Fleury S
  Transplantation. 2005
  PubMed ID: 16314800
   
  
• Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons.
  Banisadr G, Gosselin RD, Mechighel P, Rostène W, Kitabgi P, Mélik Parsadaniantz S
  J Comp Neurol. 2005
  PubMed ID: 16196033
   
  
• Stromal cell-derived factor-1 genotype, coreceptor tropism, and HIV type 1 disease progression.
  Daar ES, Lynn HS, Donfield SM, Lail A, O'Brien SJ, Huang W, Winkler CA, Hemophilia Growth and Development Study
  J Infect Dis. 2005
  PubMed ID: 16206074
   
  
• CCR2 is required for CD8-induced graft-versus-host disease.
  Terwey TH, Kim TD, Kochman AA, Hubbard VM, Lu S, Zakrzewski JL, Ramirez-Montagut T, Eng JM, Muriglan SJ, Heller G, Murphy GF, Liu C, Budak-Alpdogan T, Alpdogan O, van den Brink MR
  Blood. 2005
  PubMed ID: 16037386
   
  
• Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years.
  Ortlepp JR, Krantz C, Kimmel M, von Korff A, Vesper K, Schmitz F, Mevissen V, Janssens U, Franke A, Hanrath P, Zerres K, Hoffmann R
  Int J Cardiol. 2005
  PubMed ID: 16207551
   
  
• Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion.
  White FA, Sun J, Waters SM, Ma C, Ren D, Ripsch M, Steflik J, Cortright DN, Lamotte RH, Miller RJ
  Proc Natl Acad Sci U S A. 2005
  PubMed ID: 16174730
   
  
• IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1.
  Hu X, Park-Min KH, Ho HH, Ivashkiv LB
  J Immunol. 2005
  PubMed ID: 16148108
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• [Effect of CCR5delta32, CCR5m303, CCR2-64I and SDF1-3'A gene polymorphism on the prognosis of Chinese HIV-1 carriers]
  Wang XH, Feng TJ, Wang FS, Chen L, Shi XD, Jin L
  Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2005
  PubMed ID: 16261210
   
  
• Combined effect of CCR5-Delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission.
  Hladik F, Liu H, Speelmon E, Livingston-Rosanoff D, Wilson S, Sakchalathorn P, Hwangbo Y, Greene B, Zhu T, McElrath MJ
  J Virol. 2005
  PubMed ID: 16140745
   
  
• A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons.
  Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM
  Neuron. 2005
  PubMed ID: 16129397
   
  
• Distribution of CCR2-64I and SDF1-3'A alleles and HIV status in 7 ethnic populations of Cameroon.
  Ma L, Marmor M, Zhong P, Ewane L, Su B, Nyambi P
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 16123688
   
  
• Use of alternate coreceptors on primary cells by two HIV-1 isolates.
  Cilliers T, Willey S, Sullivan WM, Patience T, Pugach P, Coetzer M, Papathanasopoulos M, Moore JP, Trkola A, Clapham P, Morris L
  Virology. 2005
  PubMed ID: 15992849
   
  
• Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo.
  Bot I, Guo J, Van Eck M, Van Santbrink PJ, Groot PH, Hildebrand RB, Seppen J, Van Berkel TJ, Biessen EA
  Blood. 2005
  PubMed ID: 15886324
   
  
• Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo.
  Veillard NR, Steffens S, Pelli G, Lu B, Kwak BR, Gerard C, Charo IF, Mach F
  Circulation. 2005
  PubMed ID: 16061736
   
  
• CCR5delta32, CCR2-64I, and SDF1-3'A polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population.
  Paz-y-Mino C, Morillo SA, Celi AP, Witte T, Muñoz Guijarro MJ, Collantes JC, Leone PE
  Hum Biol. 2005
  PubMed ID: 16485782
   
  
• Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.
  Chen A, Mumick S, Zhang C, Lamb J, Dai H, Weingarth D, Mudgett J, Chen H, MacNeil DJ, Reitman ML, Qian S
  Obes Res. 2005
  PubMed ID: 16129712
   
  
• Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis.
  Terashima Y, Onai N, Murai M, Enomoto M, Poonpiriya V, Hamada T, Motomura K, Suwa M, Ezaki T, Haga T, Kanegasaki S, Matsushima K
  Nat Immunol. 2005
  PubMed ID: 15995708
   
  
• Coagulation cascade activation causes CC chemokine receptor-2 gene expression and mononuclear cell activation in hemodialysis patients.
  Pertosa G, Simone S, Soccio M, Marrone D, Gesualdo L, Schena FP, Grandaliano G
  J Am Soc Nephrol. 2005
  PubMed ID: 15976001
   
  
• The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source.
  Goulding C, McManus R, Murphy A, MacDonald G, Barrett S, Crowe J, Hegarty J, McKiernan S, Kelleher D
  Gut. 2005
  PubMed ID: 15863470
   
  
• CCR2 and CCR6, but not endothelial selectins, mediate the accumulation of immature dendritic cells within the lungs of mice in response to particulate antigen.
  Osterholzer JJ, Ames T, Polak T, Sonstein J, Moore BB, Chensue SW, Toews GB, Curtis JL
  J Immunol. 2005
  PubMed ID: 16002685
   
  
• Causal pathways of the effects of age and the CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on AIDS development.
  Geskus RB, Meyer L, Hubert JB, Schuitemaker H, Berkhout B, Rouzioux C, Theodorou ID, Delfraissy JF, Prins M, Coutinho RA
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 15980693
   
  
• The mouse CCR2 gene is regulated by two promoters that are responsive to plasma cholesterol and peroxisome proliferator-activated receptor gamma ligands.
  Chen Y, Green SR, Ho J, Li A, Almazan F, Quehenberger O
  Biochem Biophys Res Commun. 2005
  PubMed ID: 15896316
   
  
• The presence of leukocyte CC-chemokine receptor 2 in CCR2 knockout mice promotes atherogenesis.
  Guo J, Van Eck M, de Waard V, Maeda N, Benson GM, Groot PH, Van Berkel TJ
  Biochim Biophys Acta. 2005
  PubMed ID: 15949714
   
  
• Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis.
  Robben PM, LaRegina M, Kuziel WA, Sibley LD
  J Exp Med. 2005
  PubMed ID: 15928200
   
  
• The chemokine CCL2 modulates Ca2+ dynamics and electrophysiological properties of cultured cerebellar Purkinje neurons.
  van Gassen KL, Netzeband JG, de Graan PN, Gruol DL
  Eur J Neurosci. 2005
  PubMed ID: 15978006
   
  
• Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2.
  Abonia JP, Austen KF, Rollins BJ, Joshi SK, Flavell RA, Kuziel WA, Koni PA, Gurish MF
  Blood. 2005
  PubMed ID: 15705791
   
  
• Study of C-C chemokine receptor 2 alleles in sarcoidosis, with emphasis on family-based analysis.
  Valentonyte R, Hampe J, Croucher PJ, Müller-Quernheim J, Schwinger E, Schreiber S, Schürmann M
  Am J Respir Crit Care Med. 2005
  PubMed ID: 15750046
   
  
• Effect of CCR2 chemokine receptor polymorphism on HIV type 1 mother-to-child transmission and child survival in Western Kenya.
  Brouwer KC, Yang C, Parekh S, Mirel LB, Shi YP, Otieno J, Lal AA, Lal RB
  AIDS Res Hum Retroviruses. 2005
  PubMed ID: 15929697
   
  
• The effect of RANTES chemokine genetic variants on early HIV-1 plasma RNA among African American injection drug users.
  Duggal P, Winkler CA, An P, Yu XF, Farzadegan H, O'Brien SJ, Beaty TH, Vlahov D
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 15793370
   
  
• Relationship of five inflammatory gene polymorphisms with morbidity and mortality in 533 patients admitted to an ICU.
  Ortlepp JR, Graf J, Vesper K, Schmitz F, Mevissen V, Sucigan S, Kersten A, Weber C, Janssens U
  Inflammation. 2005
  PubMed ID: 16858645
   
  
• CCR5 chemokine receptor mediates recruitment of MHC class II-positive Langerhans cells in the mouse corneal epithelium.
  Yamagami S, Hamrah P, Miyamoto K, Miyazaki D, Dekaris I, Dawson T, Lu B, Gerard C, Dana MR
  Invest Ophthalmol Vis Sci. 2005
  PubMed ID: 15790880
   
  
• CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury.
  Moore BB, Kolodsick JE, Thannickal VJ, Cooke K, Moore TA, Hogaboam C, Wilke CA, Toews GB
  Am J Pathol. 2005
  PubMed ID: 15743780
   
  
• Protective role of the polymorphism CCR2-64I in the progression from squamous intraepithelial lesions to invasive cervical carcinoma.
  Coelho A, Matos A, Catarino R, Pinto D, Pereira D, Lopes C, Medeiros R
  Gynecol Oncol. 2005
  PubMed ID: 15721423
   
  
• Chemokine receptor CCR2 involvement in skeletal muscle regeneration.
  Warren GL, Hulderman T, Mishra D, Gao X, Millecchia L, O'Farrell L, Kuziel WA, Simeonova PP
  FASEB J. 2005
  PubMed ID: 15601671
   
  
• Monocyte chemoattractant protein-1 and CCR2 interactions are required for IFN-alpha/beta-induced inflammatory responses and antiviral defense in liver.
  Hokeness KL, Kuziel WA, Biron CA, Salazar-Mather TP
  J Immunol. 2005
  PubMed ID: 15661915
   
  
• The correlation between monocyte chemoattractant protein-1 and the arthritis of systemic lupus erythematosus among Chinese.
  Ye DQ, Hu YS, Li XP, Yang SG, Hao JH, Huang F, Zhang XJ
  Arch Dermatol Res. 2005
  PubMed ID: 15611878
   
  
• CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels.
  Maus UA, Wellmann S, Hampl C, Kuziel WA, Srivastava M, Mack M, Everhart MB, Blackwell TS, Christman JW, Schlöndorff D, Bohle RM, Seeger W, Lohmeyer J
  Am J Physiol Lung Cell Mol Physiol. 2005
  PubMed ID: 15516494
   
  
• The frequency of CCR5Delta32 and CCR2-64I in southern Iranian normal population.
  Gharagozloo M, Doroudchi M, Farjadian S, Pezeshki AM, Ghaderi A
  Immunol Lett. 2005
  PubMed ID: 15585333
   
  
• [Effects of CCR5-delta32, CCR2-64I and SDF-1-3'A polymorphic alleles on human immunodeficiency virus 1 (HIV-1) infection in the Polish population]
  Wasik TJ, Smoleń J, Kruszyński P, Bratosiewicz-Wasik J, Beniowski M
  Wiad Lek. 2005
  PubMed ID: 16529059
   
  
• Lack of association of CCR gene polymorphisms and left ventricular hypertrophy in essential hypertension.
  Mettimano M, Specchia ML, La Torre G, Bruno A, Ricciardi G, Romano-Spica V, Savi L
  Br J Biomed Sci. 2005
  PubMed ID: 16196460
   
  
• A role for MCP-1/CCR2 in interstitial lung disease in children.
  Hartl D, Griese M, Nicolai T, Zissel G, Prell C, Reinhardt D, Schendel DJ, Krauss-Etschmann S
  Respir Res. 2005
  PubMed ID: 16095529
   
  
• CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II.
  Pechkovsky DV, Goldmann T, Ludwig C, Prasse A, Vollmer E, Müller-Quernheim J, Zissel G
  Respir Res. 2005
  PubMed ID: 16033640
   
  
• [Genetic polymorphism of human immunodeficiency virus coreceptor CCR5Delta32 and CCR2-64I alleles in Chinese Yi Ethnic group in Sichuan]
  Deng XL, Hong KX, Chen JP, Ruan YH, Xu MY, Qin GM, Li K, Xing H, Shao YM
  Zhonghua Liu Xing Bing Xue Za Zhi. 2004
  PubMed ID: 15769362
   
  
• Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progression.
  Winkler CA, Hendel H, Carrington M, Smith MW, Nelson GW, O'brien SJ, Phair J, Vlahov D, Jacobson LP, Rappaport J, Vasilescu A, Bertin-Maghit S, An P, Lu W, Andrieu JM, Schächter F, Therwath A, Zagury JF
  J Acquir Immune Defic Syndr. 2004
  PubMed ID: 15602133
   
  
• Novel chemokine responsiveness and mobilization of neutrophils during sepsis.
  Speyer CL, Gao H, Rancilio NJ, Neff TA, Huffnagle GB, Sarma JV, Ward PA
  Am J Pathol. 2004
  PubMed ID: 15579460
   
  
• CCR2 polymorphisms affect neuropsychological impairment in HIV-1-infected adults.
  Singh KK, Ellis RJ, Marquie-Beck J, Letendre S, Heaton RK, Grant I, Spector SA
  J Neuroimmunol. 2004
  PubMed ID: 15579296
   
  
• C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.
  Okuma T, Terasaki Y, Kaikita K, Kobayashi H, Kuziel WA, Kawasuji M, Takeya M
  J Pathol. 2004
  PubMed ID: 15538737
   
  
• Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets.
  Schober A, Zernecke A, Liehn EA, von Hundelshausen P, Knarren S, Kuziel WA, Weber C
  Circ Res. 2004
  PubMed ID: 15528472
   
  
• Differential roles of CCL2 and CCR2 in host defense to coronavirus infection.
  Held KS, Chen BP, Kuziel WA, Rollins BJ, Lane TE
  Virology. 2004
  PubMed ID: 15518805
   
  
• Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes.
  Qu C, Edwards EW, Tacke F, Angeli V, Llodrá J, Sanchez-Schmitz G, Garin A, Haque NS, Peters W, van Rooijen N, Sanchez-Torres C, Bromberg J, Charo IF, Jung S, Lira SA, Randolph GJ
  J Exp Med. 2004
  PubMed ID: 15534368
   
  
• Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer's and Parkinson's disease.
  Huerta C, Alvarez V, Mata IF, Coto E, Ribacoba R, Martínez C, Blázquez M, Guisasola LM, Salvador C, Lahoz CH, Peña J
  Neurosci Lett. 2004
  PubMed ID: 15488313
   
  
• CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer's disease.
  Galimberti D, Fenoglio C, Lovati C, Gatti A, Guidi I, Venturelli E, Cutter GR, Mariani C, Forloni G, Pettenati C, Baron P, Conti G, Bresolin N, Scarpini E
  J Neurol Sci. 2004
  PubMed ID: 15465089
   
  
• Atherosclerosis in patients infected with HIV is influenced by a mutant monocyte chemoattractant protein-1 allele.
  Alonso-Villaverde C, Coll B, Parra S, Montero M, Calvo N, Tous M, Joven J, Masana L
  Circulation. 2004
  PubMed ID: 15466648
   
  
• [Distribution of the HIV-1 resistance-conferring alleles (CCR5delta32, CCR2-64I, and SDF1 3'A) in Russian, Ukrainian, and Belarusian populations]
  Kozhekbaeva GM, Borodina TA, Borinskaia SA, Gusar VA, Feshchenko SP, Akhmetova VL, Khusainova RI, Gupalo EIu, Spitsyn VA, Grechanina EIa, Khusnutdinova K, Iankovskiĭ NK
  Genetika. 2004
  PubMed ID: 15575507
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Impaired lung dendritic cell activation in CCR2 knockout mice.
  Chiu BC, Freeman CM, Stolberg VR, Hu JS, Zeibecoglou K, Lu B, Gerard C, Charo IF, Lira SA, Chensue SW
  Am J Pathol. 2004
  PubMed ID: 15466386
   
  
• Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy.
  Hoffmann S, Park J, Jacobson LM, Muehrer RJ, Lorentzen D, Kleiner D, Becker YT, Hullett DA, Mannon R, Kirk AD, Becker BN
  Kidney Int. 2004
  PubMed ID: 15458467
   
  
• CCR2 genotype and disease progression in a treated population of HIV type 1-infected women.
  Philpott S, Burger H, Tarwater PM, Lu M, Gange SJ, Anastos K, Cohen M, Greenblatt RM, Kovacs A, Minkoff H, Young M, Miotti P, Dupuis M, Weiser B
  Clin Infect Dis. 2004
  PubMed ID: 15472820
   
  
• Analysis of genetic polymorphisms in CCR5, CCR2, stromal cell-derived factor-1, RANTES, and dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin in seronegative individuals repeatedly exposed to HIV-1.
  Liu H, Hwangbo Y, Holte S, Lee J, Wang C, Kaupp N, Zhu H, Celum C, Corey L, McElrath MJ, Zhu T
  J Infect Dis. 2004
  PubMed ID: 15319853
   
  
• Expression of the chemokine receptor CCR2 on immature B cells negatively regulates their cytoskeletal rearrangement and migration.
  Flaishon L, Becker-Herman S, Hart G, Levo Y, Kuziel WA, Shachar I
  Blood. 2004
  PubMed ID: 15126315
   
  
• Distribution of CCR5-delta32, CCR2-64I, and SDF1-3'A mutations in populations from the Brazilian Amazon region.
  De Pinho Lott Carvalhaes FA, Cardoso GL, Hamoy IG, Liu YT, Guerreiro JF
  Hum Biol. 2004
  PubMed ID: 15754978
   
  
• Targeted deletion of CC chemokine receptor 2 attenuates left ventricular remodeling after experimental myocardial infarction.
  Kaikita K, Hayasaki T, Okuma T, Kuziel WA, Ogawa H, Takeya M
  Am J Pathol. 2004
  PubMed ID: 15277218
   
  
• Rat aortic MCP-1 and its receptor CCR2 increase with age and alter vascular smooth muscle cell function.
  Spinetti G, Wang M, Monticone R, Zhang J, Zhao D, Lakatta EG
  Arterioscler Thromb Vasc Biol. 2004
  PubMed ID: 15178559
   
  
• FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.
  Yopp AC, Fu S, Honig SM, Randolph GJ, Ding Y, Krieger NR, Bromberg JS
  J Immunol. 2004
  PubMed ID: 15240672
   
  
• Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis.
  Sørensen TL, Ransohoff RM, Strieter RM, Sellebjerg F
  Eur J Neurol. 2004
  PubMed ID: 15257681
   
  
• Association of highly active antiretroviral therapy failure with chemokine receptor 5 wild type.
  Bogner JR, Lutz B, Klein HG, Pollerer C, Troendle U, Goebel FD
  HIV Med. 2004
  PubMed ID: 15236615
   
  
• Analysis of CCR5-Delta 32 and CCR2-V64I polymorphisms in a cohort of Spanish HCV patients using real-time polymerase chain reaction and fluorescence resonance energy transfer technologies.
  Ruiz-Ferrer M, Barroso N, Antiñolo G, Aguilar-Reina J
  J Viral Hepat. 2004
  PubMed ID: 15230854
   
  
• Blockade of CCR2 ameliorates progressive fibrosis in kidney.
  Kitagawa K, Wada T, Furuichi K, Hashimoto H, Ishiwata Y, Asano M, Takeya M, Kuziel WA, Matsushima K, Mukaida N, Yokoyama H
  Am J Pathol. 2004
  PubMed ID: 15215179
   
  
• CCR5 promoter human haplogroups associated with HIV-1 disease progression in Thai injection drug users.
  Nguyen L, Li M, Chaowanachan T, Hu DJ, Vanichseni S, Mock PA, van Griensven F, Martin M, Sangkum U, Choopanya K, Tappero JW, Lal RB, Yang C
  AIDS. 2004
  PubMed ID: 15362666
   
  
• CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis.
  Peters W, Cyster JG, Mack M, Schlöndorff D, Wolf AJ, Ernst JD, Charo IF
  J Immunol. 2004
  PubMed ID: 15187146
   
  
• MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis.
  Peterson KE, Errett JS, Wei T, Dimcheff DE, Ransohoff R, Kuziel WA, Evans L, Chesebro B
  J Virol. 2004
  PubMed ID: 15163738
   
  
• Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling.
  Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, Tsuchihashi M, Sugaya T, Charo IF, Kura S, Tsuzuki T, Ishibashi T, Takeshita A, Egashira K
  Circ Res. 2004
  PubMed ID: 15059935
   
  
• Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients.
  Mascheretti S, Hinrichsen H, Ross S, Buggisch P, Hampe J, Foelsch UR, Schreiber S
  Clin Exp Immunol. 2004
  PubMed ID: 15086398
   
  
• Role of CC chemokines in skeletal muscle functional restoration after injury.
  Warren GL, O'Farrell L, Summan M, Hulderman T, Mishra D, Luster MI, Kuziel WA, Simeonova PP
  Am J Physiol Cell Physiol. 2004
  PubMed ID: 15075201
   
  
• Lack of association of human chemokine receptor gene polymorphisms CCR2-64I and CCR5-Delta32 with autoimmune Addison's disease.
  Gambelunghe G, Ghaderi M, Gharizadeh B, Brozzetti A, Tortoioli C, Del Sindaco P, Sanjeevi CB, Hjelmström P, Sirsjö A, Nyren P, Santeusanio F, Falorni A
  Eur J Immunogenet. 2004
  PubMed ID: 15086346
   
  
• Collateral artery growth (arteriogenesis) after experimental arterial occlusion is impaired in mice lacking CC-chemokine receptor-2.
  Heil M, Ziegelhoeffer T, Wagner S, Fernández B, Helisch A, Martin S, Tribulova S, Kuziel WA, Bachmann G, Schaper W
  Circ Res. 2004
  PubMed ID: 14963007
   
  
• A critical role for CCR2/MCP-1 interactions in the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation.
  Hildebrandt GC, Duffner UA, Olkiewicz KM, Corrion LA, Willmarth NE, Williams DL, Clouthier SG, Hogaboam CM, Reddy PR, Moore BB, Kuziel WA, Liu C, Yanik G, Cooke KR
  Blood. 2004
  PubMed ID: 14615370
   
  
• Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States.
  Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA
  J Acquir Immune Defic Syndr. 2004
  PubMed ID: 15076247
   
  
• Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis.
  Quinones MP, Ahuja SK, Jimenez F, Schaefer J, Garavito E, Rao A, Chenaux G, Reddick RL, Kuziel WA, Ahuja SS
  J Clin Invest. 2004
  PubMed ID: 15067318
   
  
• Analysis of the involvement of CCR5-Delta32 and CCR2-V64I variants in the development of endometriosis.
  Antiñolo G, Fernández RM, Noval JA, Moliní JL, Borrego S
  Mol Hum Reprod. 2004
  PubMed ID: 14981141
   
  
• Fraction of cases of acquired immunodeficiency syndrome prevented by the interactions of identified restriction gene variants.
  Silverberg MJ, Smith MW, Chmiel JS, Detels R, Margolick JB, Rinaldo CR, O'Brien SJ, Muñoz A
  Am J Epidemiol. 2004
  PubMed ID: 14742283
   
  
• Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells.
  Panoskaltsis-Mortari A, Hermanson JR, Taras E, Wangensteen OD, Charo IF, Rollins BJ, Blazar BR
  Am J Physiol Lung Cell Mol Physiol. 2004
  PubMed ID: 14527928
   
  
• Expression of chemokine receptors CXCR4, CCR2, CCR5 and CX3CR1 in neural progenitor cells isolated from the subventricular zone of the adult rat brain.
  Ji JF, He BP, Dheen ST, Tay SS
  Neurosci Lett. 2004
  PubMed ID: 14732474
   
  
• Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells.
  Brühl H, Cihak J, Schneider MA, Plachý J, Rupp T, Wenzel I, Shakarami M, Milz S, Ellwart JW, Stangassinger M, Schlöndorff D, Mack M
  J Immunol. 2004
  PubMed ID: 14707060
   
  
• Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2.
  Koth LL, Rodriguez MW, Bernstein XL, Chan S, Huang X, Charo IF, Rollins BJ, Erle DJ
  Respir Res. 2004
  PubMed ID: 15377395
   
  
• CCR5 promoter polymorphism influences the interferon response of patients with chronic hepatitis C in Japan.
  Konishi I, Horiike N, Hiasa Y, Michitaka K, Onji M
  Intervirology. 2004
  PubMed ID: 15192276
   
  
• Prevalence of alleles associated with HIV resistance in Russia.
  Ryabov GS, Kazennova EV, Bobkova MR, Bobkov AF
  Genet Test. 2004
  PubMed ID: 15140377
   
  
• HIV-1 infection and chemokine receptor modulation.
  Ruibal-Ares BH, Belmonte L, Baré PC, Parodi CM, Massud I, de Bracco MM
  Curr HIV Res. 2004
  PubMed ID: 15053339
   
  
• Estrogen decreases expression of chemokine receptors, and suppresses chemokine bioactivity in murine monocytes.
  Janis K, Hoeltke J, Nazareth M, Fanti P, Poppenberg K, Aronica SM
  Am J Reprod Immunol. 2004
  PubMed ID: 14725563
   
  
• Expression and functional implications of CCR2 expression on murine alveolar epithelial cells.
  Christensen PJ, Du M, Moore B, Morris S, Toews GB, Paine R
  Am J Physiol Lung Cell Mol Physiol. 2004
  PubMed ID: 14656700
   
  
• Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis.
  Shahrara S, Amin MA, Woods JM, Haines GK, Koch AE
  Arthritis Rheum. 2003
  PubMed ID: 14674010
   
  
• Sequential MyD88-independent and -dependent activation of innate immune responses to intracellular bacterial infection.
  Serbina NV, Kuziel W, Flavell R, Akira S, Rollins B, Pamer EG
  Immunity. 2003
  PubMed ID: 14670305
   
  
• Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection.
  Hellier S, Frodsham AJ, Hennig BJ, Klenerman P, Knapp S, Ramaley P, Satsangi J, Wright M, Zhang L, Thomas HC, Thursz M, Hill AV
  Hepatology. 2003
  PubMed ID: 14647058
   
  
• C-C chemokine receptor 2 gene polymorphism in Japanese patients with multiple sclerosis.
  Miyagishi R, Niino M, Fukazawa T, Yabe I, Kikuchi S, Tashiro K
  J Neuroimmunol. 2003
  PubMed ID: 14644039
   
  
• Monocyte chemoattractant protein-1 (MCP-1/CCL2) in experimental autoimmune orchitis.
  Guazzone VA, Rival C, Denduchis B, Lustig L
  J Reprod Immunol. 2003
  PubMed ID: 14638441
   
  
• Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection.
  Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA
  J Infect Dis. 2003
  PubMed ID: 14624371
   
  
• Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase.
  Stamatovic SM, Keep RF, Kunkel SL, Andjelkovic AV
  J Cell Sci. 2003
  PubMed ID: 14576355
   
  
• C-C chemokine receptor 2 and sarcoidosis: association with Lofgren's syndrome.
  Spagnolo P, Renzoni EA, Wells AU, Sato H, Grutters JC, Sestini P, Abdallah A, Gramiccioni E, Ruven HJ, du Bois RM, Welsh KI
  Am J Respir Crit Care Med. 2003
  PubMed ID: 12882757
   
  
• [Distribution of the HIV/AIDS associated CCR5Delta32,CCR2b-64I,SDF1-3'A allelesin Chinese Dai and Chingpaw populations from Dehong autonomous prefecture of Yunnan Province]
  Ye JJ, Wang FS, Peng L, Jin L, Ding M, Liu MX
  Yi Chuan. 2003
  PubMed ID: 15639953
   
  
• CC chemokine receptor 2 expression in donor cells serves an essential role in graft-versus-host-disease.
  Rao AR, Quinones MP, Garavito E, Kalkonde Y, Jimenez F, Gibbons C, Perez J, Melby P, Kuziel W, Reddick RL, Ahuja SK, Ahuja SS
  J Immunol. 2003
  PubMed ID: 14568968
   
  
• An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice.
  Ambati J, Anand A, Fernandez S, Sakurai E, Lynn BC, Kuziel WA, Rollins BJ, Ambati BK
  Nat Med. 2003
  PubMed ID: 14566334
   
  
• Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis.
  Zhao X, Gharizadeh B, Hjelmström P, Pirskanen R, Nyrén P, Lefvert AK, Ghaderi M
  Int J Mol Med. 2003
  PubMed ID: 14533004
   
  
• MCP-1 deficiency is associated with reduced intimal hyperplasia after arterial injury.
  Kim WJ, Chereshnev I, Gazdoiu M, Fallon JT, Rollins BJ, Taubman MB
  Biochem Biophys Res Commun. 2003
  PubMed ID: 14550294
   
  
• CCR2 signaling contributes to ischemia-reperfusion injury in kidney.
  Furuichi K, Wada T, Iwata Y, Kitagawa K, Kobayashi K, Hashimoto H, Ishiwata Y, Asano M, Wang H, Matsushima K, Takeya M, Kuziel WA, Mukaida N, Yokoyama H
  J Am Soc Nephrol. 2003
  PubMed ID: 14514728
   
  
• CC chemokine ligand 2 and its receptor regulate mucosal production of IL-12 and TGF-beta in high dose oral tolerance.
  DePaolo RW, Rollins BJ, Kuziel W, Karpus WJ
  J Immunol. 2003
  PubMed ID: 14500652
   
  
• Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.
  Arias DA, Navenot JM, Zhang WB, Broach J, Peiper SC
  J Biol Chem. 2003
  PubMed ID: 12837756
   
  
• Role of monocyte chemoattractant protein-1 and its receptor,CCR-2, in the pathogenesis of bleomycin-induced scleroderma.
  Yamamoto T, Nishioka K
  J Invest Dermatol. 2003
  PubMed ID: 12925209
   
  
• Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population.
  Munerato P, Azevedo ML, Sucupira MC, Pardini R, Pinto GH, Catroxo M, Souza IE, Diaz RS
  Braz J Infect Dis. 2003
  PubMed ID: 14533983
   
  
• Induction of heme oxygenase-1 in monocytes suppresses angiotensin II-elicited chemotactic activity through inhibition of CCR2: role of bilirubin and carbon monoxide generated by the enzyme.
  Morita T, Imai T, Yamaguchi T, Sugiyama T, Katayama S, Yoshino G
  Antioxid Redox Signal. 2003
  PubMed ID: 13678532
   
  
• Chemokine receptor CCR2/CCR5 polymorphism in Spanish patients with systemic lupus erythematosus.
  Aguilar F, Núñez-Roldán A, Torres B, Wichmann I, Sánchez-Román J, González-Escribano MF
  J Rheumatol. 2003
  PubMed ID: 12913933
   
  
• Association between polymorphisms in the human chemokine receptor genes CCR2 and CX3CR1 and rheumatoid arthritis.
  Bayley JP, Baggen JM, van der Pouw-Kraan T, Crusius JB, Huizinga TW, Verweij CL
  Tissue Antigens. 2003
  PubMed ID: 12889997
   
  
• Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis.
  Ioannidis JP, Contopoulos-Ioannidis DG, Rosenberg PS, Goedert JJ, De Rossi A, Espanol T, Frenkel L, Mayaux MJ, Newell ML, Pahwa SG, Rousseau C, Scarlatti G, Sei S, Sen L, O'Brien TR, HIV Host Genetics International Meta-Analysis Group
  AIDS. 2003
  PubMed ID: 12853745
   
  
• CC chemokine receptor (CCR)2 polymorphism in Czech patients with myocardial infarction.
  Petrkova J, Cermakova Z, Drabek J, Lukl J, Petrek M
  Immunol Lett. 2003
  PubMed ID: 12853162
   
  
• Impaired hepatic granuloma formation in mice deficient in C-C chemokine receptor 2.
  Jinnouchi K, Terasaki Y, Fujiyama S, Tomita K, Kuziel WA, Maeda N, Takahashi K, Takeya M
  J Pathol. 2003
  PubMed ID: 12845637
   
  
• The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization.
  Tsutsumi C, Sonoda KH, Egashira K, Qiao H, Hisatomi T, Nakao S, Ishibashi M, Charo IF, Sakamoto T, Murata T, Ishibashi T
  J Leukoc Biol. 2003
  PubMed ID: 12832439
   
  
• Inhibition of corneal neovascularization by genetic ablation of CCR2.
  Ambati BK, Joussen AM, Kuziel WA, Adamis AP, Ambati J
  Cornea. 2003
  PubMed ID: 12827053
   
  
• Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2.
  Abbadie C, Lindia JA, Cumiskey AM, Peterson LB, Mudgett JS, Bayne EK, DeMartino JA, MacIntyre DE, Forrest MJ
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 12808141
   
  
• Determination of the CCR2-64I/CCR5-59653T haplotype linkage disequilibrium in a sample of Polish population.
  Lewandowska M, Trzeciak WH, Jagodzinski PP
  Genetika. 2003
  PubMed ID: 12884524
   
  
• Chemokine receptor (CCR2) genotype is associated with myocardial infarction and heart failure in patients under 65 years of age.
  Ortlepp JR, Vesper K, Mevissen V, Schmitz F, Janssens U, Franke A, Hanrath P, Weber C, Zerres K, Hoffmann R
  J Mol Med. 2003
  PubMed ID: 12719858
   
  
• Prediction of genetic risk for hypertension.
  Izawa H, Yamada Y, Okada T, Tanaka M, Hirayama H, Yokota M
  Hypertension. 2003
  PubMed ID: 12654703
   
  
• Hormonal and embryonic regulation of chemokine receptors CXCR1, CXCR4, CCR5 and CCR2B in the human endometrium and the human blastocyst.
  Dominguez F, Galan A, Martin JJ, Remohi J, Pellicer A, Simón C
  Mol Hum Reprod. 2003
  PubMed ID: 12651900
   
  
• Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis.
  Maus UA, Waelsch K, Kuziel WA, Delbeck T, Mack M, Blackwell TS, Christman JW, Schlöndorff D, Seeger W, Lohmeyer J
  J Immunol. 2003
  PubMed ID: 12626586
   
  
• Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis.
  Guo J, Van Eck M, Twisk J, Maeda N, Benson GM, Groot PH, Van Berkel TJ
  Arterioscler Thromb Vasc Biol. 2003
  PubMed ID: 12615695
   
  
• Induction of low dose oral tolerance in monocyte chemoattractant protein-1- and CCR2-deficient mice.
  Gonnella PA, Kodali D, Weiner HL
  J Immunol. 2003
  PubMed ID: 12594253
   
  
• Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection.
  Mulherin SA, O'Brien TR, Ioannidis JP, Goedert JJ, Buchbinder SP, Coutinho RA, Jamieson BD, Meyer L, Michael NL, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Theodorou ID, Vlahov D, Rosenberg PS, International Meta-Analysis of HIV Host Genetics
  AIDS. 2003
  PubMed ID: 12556692
   
  
• Population survey of CCR5 delta32, CCR5 m303, CCR2b 64I, and SDF1 3'A allele frequencies in indigenous Chinese healthy individuals, and in HIV-1-infected and HIV-1-uninfected individuals in HIV-1 risk groups.
  Wang FS, Hong WG, Cao Y, Liu MX, Jin L, Hu LP, Wang Z, Feng TJ, Hou J, Zhang B, Shi M, Xu DP, Lei ZY, Wang B, Liu ZD, Ye JJ, Peng L, Qiu Y, Winkler C
  J Acquir Immune Defic Syndr. 2003
  PubMed ID: 12571520
   
  
• Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C.
  Promrat K, McDermott DH, Gonzalez CM, Kleiner DE, Koziol DE, Lessie M, Merrell M, Soza A, Heller T, Ghany M, Park Y, Alter HJ, Hoofnagle JH, Murphy PM, Liang TJ
  Gastroenterology. 2003
  PubMed ID: 12557141
   
  
• In CCR2-/- mice monocyte recruitment and egress of LDL cholesterol in vivo is impaired.
  Stein O, Dabach Y, Ben-Naim M, Halperin G, Charo IF, Stein Y
  Biochem Biophys Res Commun. 2003
  PubMed ID: 12504109
   
  
• CCR5 and CCR2 gene polymorphisms in hypertensive patients.
  Mettimano M, Specchia ML, Ianni A, Arzani D, Ricciardi G, Savi L, Romano-Spica V
  Br J Biomed Sci. 2003
  PubMed ID: 12680626
   
  
• Chemokine receptor genotype and response to interleukin-2 therapy in HIV-1-infected individuals.
  Clegg A, Williamson P, Biti R, Cooper D, Emery S, Carr A, Stewart G
  Clin Immunol. 2003
  PubMed ID: 12584049
   
  
• Experimental autoimmune encephalomyelitis (EAE) in CCR2(-/-) mice: susceptibility in multiple strains.
  Gaupp S, Pitt D, Kuziel WA, Cannella B, Raine CS
  Am J Pathol. 2003
  PubMed ID: 12507897
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice.
  Huang D, Tani M, Wang J, Han Y, He TT, Weaver J, Charo IF, Tuohy VK, Rollins BJ, Ransohoff RM
  J Neurosci. 2002
  PubMed ID: 12486156
   
  
• CC chemokine receptor 5 delta32 and CC chemokine receptor 2 64I polymorphisms do not influence the virologic and immunologic response to antiretroviral combination therapy in human immunodeficiency virus type 1-infected patients.
  Wit FW, van Rij RP, Weverling GJ, Lange JM, Schuitemaker H
  J Infect Dis. 2002
  PubMed ID: 12447757
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• Differential expression of MCP-1 and its receptor CCR2 in glucose primed human mesangial cells.
  Janssen U, Sowa E, Marchand P, Floege J, Phillips AO, Radeke HH
  Nephron. 2002
  PubMed ID: 12399623
   
  
• Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.
  Kiss H, Darai E, Kiss C, Kost-Alimova M, Klein G, Dumanski JP, Imreh S
  Mamm Genome. 2002
  PubMed ID: 12461651
   
  
• Val64Ile polymorphism in the C-C chemokine receptor 2 is associated with reduced coronary artery calcification.
  Valdes AM, Wolfe ML, O'Brien EJ, Spurr NK, Gefter W, Rut A, Groot PH, Rader DJ
  Arterioscler Thromb Vasc Biol. 2002
  PubMed ID: 12426226
   
  
• Mycobacterium tuberculosis in chemokine receptor 2-deficient mice: influence of dose on disease progression.
  Scott HM, Flynn JL
  Infect Immun. 2002
  PubMed ID: 12379669
   
  
• The presence of chemokine (MCP-1, MIP-1alpha, MIP-1beta, IP-10, RANTES)-positive cells and chemokine receptor (CCR5, CXCR3)-positive cells in inflamed human gingival tissues.
  Kabashima H, Yoneda M, Nagata K, Hirofuji T, Maeda K
  Cytokine. 2002
  PubMed ID: 12445801
   
  
• HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels.
  Gonzalez E, Rovin BH, Sen L, Cooke G, Dhanda R, Mummidi S, Kulkarni H, Bamshad MJ, Telles V, Anderson SA, Walter EA, Stephan KT, Deucher M, Mangano A, Bologna R, Ahuja SS, Dolan MJ, Ahuja SK
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12374865
   
  
• Functional expression of CCR2 by human fetal astrocytes.
  Andjelkovic AV, Song L, Dzenko KA, Cong H, Pachter JS
  J Neurosci Res. 2002
  PubMed ID: 12271471
   
  
• A Monocyte chemoattractant protein-1 (MCP-1) polymorphism and outcome after renal transplantation.
  Krüger B, Schröppel B, Ashkan R, Marder B, Zülke C, Murphy B, Krämer BK, Fischereder M
  J Am Soc Nephrol. 2002
  PubMed ID: 12239249
   
  
• [Do polymorphisms of the SDF1 and CCR2b genes modify the course of hepatitis C or HIV/HCV co-infection?]
  Woitas RP, Ahlenstiel G, Iwan A, Rockstroh JK, Brackmann HH, Kupfer B, Matz B, Offergeld R, Sauerbruch T, Spengler U
  Dtsch Med Wochenschr. 2002
  PubMed ID: 12215924
   
  
• Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo.
  McQuibban GA, Gong JH, Wong JP, Wallace JL, Clark-Lewis I, Overall CM
  Blood. 2002
  PubMed ID: 12149192
   
  
• The impact of polymorphisms in chemokine and chemokine receptors on outcomes in liver transplantation.
  Schröppel B, Fischereder M, Ashkar R, Lin M, Krämer BK, Mardera B, Schiano T, Murphy B
  Am J Transplant. 2002
  PubMed ID: 12201365
   
  
• The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice.
  Maus U, von Grote K, Kuziel WA, Mack M, Miller EJ, Cihak J, Stangassinger M, Maus R, Schlöndorff D, Seeger W, Lohmeyer J
  Am J Respir Crit Care Med. 2002
  PubMed ID: 12153956
   
  
• Association of the CCR2 chemokine receptor gene polymorphism with myocardial infarction.
  Voevoda MI, Ustinov SN, Yudin NS, Dolgikh MM, Kuznetsova TN, Maksimov VN, Kulikov IV, Gromov AA, Shabalin AV, Semaeva EV, Kobzev VF, Baum SR, Gafarov VV, Malyutina SK, Romaschenko AG, Nikitin Y
  Dokl Biol Sci. 2002
  PubMed ID: 12469616
   
  
• Structural analysis of human CCR2b and primate CCR2b by molecular modeling and molecular dynamics simulation.
  Shi XF, Liu S, Xiangyu J, Zhang Y, Huang J, Liu S, Liu CQ
  J Mol Model. 2002
  PubMed ID: 12192431
   
  
• Association of a polymorphism of the CC chemokine receptor-2 gene with bone mineral density.
  Yamada Y, Ando F, Niino N, Shimokata H
  Genomics. 2002
  PubMed ID: 12079277
   
  
• Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity.
  Kim CH, Johnston B, Butcher EC
  Blood. 2002
  PubMed ID: 12070001
   
  
• Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys.
  Egashira K, Zhao Q, Kataoka C, Ohtani K, Usui M, Charo IF, Nishida K, Inoue S, Katoh M, Ichiki T, Takeshita A
  Circ Res. 2002
  PubMed ID: 12065319
   
  
• Ccr2 regulates the level of MCP-1/CCL2 in vitro and at inflammatory sites and controls T cell activation in response to alloantigen.
  Tylaska LA, Boring L, Weng W, Aiello R, Charo IF, Rollins BJ, Gladue RP
  Cytokine. 2002
  PubMed ID: 12126640
   
  
• Induction of MCP-1 expression in airway epithelial cells: role of CCR2 receptor in airway epithelial injury.
  Lundien MC, Mohammed KA, Nasreen N, Tepper RS, Hardwick JA, Sanders KL, Van Horn RD, Antony VB
  J Clin Immunol. 2002
  PubMed ID: 12078856
   
  
• Prevalence of HIV co-receptor polymorphisms in HIV-infected patients and uninfected volunteers in Luxembourg.
  Roman F, Franck N, Burgy C, Servais J, Zimmer JM, Mossong J, Goubau P, Schneider F, Hemmer R, Schmit JC
  HIV Clin Trials. 2002
  PubMed ID: 12032878
   
  
• Targeting monocyte recruitment in CNS autoimmune disease.
  Izikson L, Klein RS, Luster AD, Weiner HL
  Clin Immunol. 2002
  PubMed ID: 12027417
   
  
• Chemokine receptor gene polymorphisms and risk of human T lymphotropic virus type I infection in Jamaica.
  Hisada M, Lal RB, Masciotra S, Rudolph DL, Martin MP, Carrington M, Wilks RJ, Manns A
  J Infect Dis. 2002
  PubMed ID: 12001056
   
  
• Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse.
  Dambach DM, Watson LM, Gray KR, Durham SK, Laskin DL
  Hepatology. 2002
  PubMed ID: 11981759
   
  
• Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity.
  Traynor TR, Herring AC, Dorf ME, Kuziel WA, Toews GB, Huffnagle GB
  J Immunol. 2002
  PubMed ID: 11971015
   
  
• CCR2 and CCR5 genotypes in HIV type 1-infected adolescents: limited contributions to variability in plasma HIV type 1 RNA concentration in the absence of antiretroviral therapy.
  Tang J, Wilson CM, Schaen M, Myracle A, Douglas SD, Kaslow RA, REACH Study Group
  AIDS Res Hum Retroviruses. 2002
  PubMed ID: 11958683
   
  
• Chemokine/chemokine receptor nomenclature.
  IUIS/WHO Subcommittee on Chemokine Nomenclature
  J Immunol Methods. 2002
  PubMed ID: 12080938
   
  
• Heterozygosity for CCR5-Delta32 but not CCR2b-64I protects against certain intracellular pathogens.
  Ashton LJ, Stewart GJ, Biti R, Law M, Cooper DA, Kaldor JM
  HIV Med. 2002
  PubMed ID: 12010355
   
  
• Chemokine receptor polymorphisms and GB virus C status in HIV-positive patients.
  Tillmann HL, Stoll M, Manns MP, Schmidt RE, Heiken H
  AIDS. 2002
  PubMed ID: 11964548
   
  
• IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.
  Zhu Z, Ma B, Zheng T, Homer RJ, Lee CG, Charo IF, Noble P, Elias JA
  J Immunol. 2002
  PubMed ID: 11884467
   
  
• Genetic analysis of HIV-1 discordant couples in Thailand: association of CCR2 64I homozygosity with HIV-1-negative status.
  Louisirirotchanakul S, Liu H, Roongpisuthipong A, Nakayama EE, Takebe Y, Shioda T, Wasi C
  J Acquir Immune Defic Syndr. 2002
  PubMed ID: 11873083
   
  
• Chemokine receptor polymorphism and risk of acute rejection in human renal transplantation.
  Abdi R, Tran TB, Sahagun-Ruiz A, Murphy PM, Brenner BM, Milford EL, McDermott DH
  J Am Soc Nephrol. 2002
  PubMed ID: 11856781
   
  
• [Frequencies of the CCR2-64I and SDF1-3'A alleles associated with progression of the HIV-1 disease in healthy individuals from Moscow]
  Riabov GS, Kazennova EV, Bobkov AF
  Genetika. 2002
  PubMed ID: 11898620
   
  
• Differential expression of the isoforms for the monocyte chemoattractant protein-1 receptor, CCR2, in monocytes.
  Tanaka S, Green SR, Quehenberger O
  Biochem Biophys Res Commun. 2002
  PubMed ID: 11779135
   
  
• Distribution of two HIV-1-resistant polymorphisms (SDF1-3'A and CCR2-64I alleles) in the Polish population.
  Lewandowska M, Franciszkiewicz K, Prokop J, Ofori H, Jagodzinski PP
  J Hum Genet. 2002
  PubMed ID: 12436194
   
  
• C-C chemokine receptor 2 and C-C chemokine receptor 5 genotypes in patients treated for chronic hepatitis C virus infection.
  Dorak MT, Folayan GO, Niwas S, van Leeuwen DJ, Yee LJ, Tang J, Kaslow RA
  Immunol Res. 2002
  PubMed ID: 12403355
   
  
• Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.
  Zee RY, Hoh J, Cheng S, Reynolds R, Grow MA, Silbergleit A, Walker K, Steiner L, Zangenberg G, Fernandez-Ortiz A, Macaya C, Pintor E, Fernandez-Cruz A, Ott J, Lindpainter K
  Pharmacogenomics J. 2002
  PubMed ID: 12082592
   
  
• Coreceptor utilization of HIV type 1 subtype E viral isolates from Thai men with HIV type 1-infected and uninfected wives.
  Utaipat U, Duerr A, Rudolph DL, Yang C, Butera ST, Lupo D, Pisell T, Tangmunkongvorakul A, Kamtorn N, Nantachit N, Nagachinta T, Suriyanon V, Robison V, Nelson KE, Sittisombut N, Lal RB
  AIDS Res Hum Retroviruses. 2002
  PubMed ID: 11804551
   
  
• Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces.
  Vanbervliet B, Homey B, Durand I, Massacrier C, Aït-Yahia S, de Bouteiller O, Vicari A, Caux C
  Eur J Immunol. 2002
  PubMed ID: 11782014
   
  
• Chemokine receptor genotype is associated with diabetic nephropathy in Japanese with type 2 diabetes.
  Nakajima K, Tanaka Y, Nomiyama T, Ogihara T, Piao L, Sakai K, Onuma T, Kawamori R
  Diabetes. 2002
  PubMed ID: 11756347
   
  
• Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression.
  Tang J, Shelton B, Makhatadze NJ, Zhang Y, Schaen M, Louie LG, Goedert JJ, Seaberg EC, Margolick JB, Mellors J, Kaslow RA
  J Virol. 2002
  PubMed ID: 11752157
   
  
• Distribution of HIV-1 resistance-conferring polymorphic alleles SDF-1-3'A, CCR2-64I and CCR5-Delta32 in diverse populations of Andhra Pradesh, South India.
  Ramana GV, Vasanthi A, Khaja M, Su B, Govindaiah V, Jin L, Singh L, Chakraborty R
  J Genet. 2001
  PubMed ID: 11988632
   
  
• The chemokine receptor CCR2 mediates the binding and internalization of monocyte chemoattractant protein-1 along brain microvessels.
  Dzenko KA, Andjelkovic AV, Kuziel WA, Pachter JS
  J Neurosci. 2001
  PubMed ID: 11717355
   
  
• Associations of CCR5, CCR2, and stromal cell-derived factor 1 genotypes with human immunodeficiency virus disease progression in patients receiving nucleoside therapy.
  Lathey JL, Tierney C, Chang SY, D'Aquila RT, Bettendorf DM, Alexander HC, Santini CD, Hughes AM, Barroga CF, Spector SA, Landes JE, Hammer SM, Katzenstein DA
  J Infect Dis. 2001
  PubMed ID: 11709782
   
  
• Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.
  Ioannidis JP, Rosenberg PS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP, Coutinho RA, Eugen-Olsen J, Gallart T, Katzenstein TL, Kostrikis LG, Kuipers H, Louie LG, Mallal SA, Margolick JB, Martinez OP, Meyer L, Michael NL, Operskalski E, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Stewart GJ, Theodorou ID, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury JF, O'Brien TR, International Meta-Analysis of HIV Host Genetics
  Ann Intern Med. 2001
  PubMed ID: 11694103
   
  
• Genotypes and polymorphisms of mutant CCR5-delta 32, CCR2-64I and SDF1-3' a HIV-1 resistance alleles in indigenous Han Chinese.
  Wang F, Jin L, Lei Z, Shi H, Hong W, Xu D, Jiang J, Wang Y, Zhang B, Liu M, Li Y
  Chin Med J (Engl). 2001
  PubMed ID: 11729511
   
  
• Adverse effect of the CCR5 promoter -2459A allele on HIV-1 disease progression.
  Knudsen TB, Kristiansen TB, Katzenstein TL, Eugen-Olsen J, Copenhagen AIDS Study Group
  J Med Virol. 2001
  PubMed ID: 11596075
   
  
• Lack of CCR2 results in increased mortality and impaired leukocyte activation and trafficking following infection of the central nervous system with a neurotropic coronavirus.
  Chen BP, Kuziel WA, Lane TE
  J Immunol. 2001
  PubMed ID: 11591787
   
  
• Protection from pulmonary fibrosis in the absence of CCR2 signaling.
  Moore BB, Paine R, Christensen PJ, Moore TA, Sitterding S, Ngan R, Wilke CA, Kuziel WA, Toews GB
  J Immunol. 2001
  PubMed ID: 11591761
   
  
• Functional expression of chemokine receptor 2 by normal human eosinophils.
  Dunzendorfer S, Kaneider NC, Kaser A, Woell E, Frade JM, Mellado M, Martínez-Alonso C, Wiedermann CJ
  J Allergy Clin Immunol. 2001
  PubMed ID: 11590385
   
  
• Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus.
  Glass WG, Liu MT, Kuziel WA, Lane TE
  Virology. 2001
  PubMed ID: 11543653
   
  
• Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD). Coincidence of elevated Lp(a) and MCP-1 -2518 G/G genotype in CAD patients.
  Szalai C, Duba J, Prohászka Z, Kalina A, Szabó T, Nagy B, Horváth L, Császár A
  Atherosclerosis. 2001
  PubMed ID: 11500196
   
  
• Distribution of CCR5-Delta 32 and CCR2-64I alleles in an Argentine Amerindian population.
  Mangano A, Theiler G, Sala L, Capucchio M, Fainboim L, Sen L
  Tissue Antigens. 2001
  PubMed ID: 11696224
   
  
• Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome.
  Belperio JA, Keane MP, Burdick MD, Lynch JP, Xue YY, Berlin A, Ross DJ, Kunkel SL, Charo IF, Strieter RM
  J Clin Invest. 2001
  PubMed ID: 11518728
   
  
• Human CC chemokine liver-expressed chemokine/CCL16 is a functional ligand for CCR1, CCR2 and CCR5, and constitutively expressed by hepatocytes.
  Nomiyama H, Hieshima K, Nakayama T, Sakaguchi T, Fujisawa R, Tanase S, Nishiura H, Matsuno K, Takamori H, Tabira Y, Yamamoto T, Miura R, Yoshie O
  Int Immunol. 2001
  PubMed ID: 11470772
   
  
• Lack of effect of chemokine receptor CCR2b gene polymorphism (64I) on HIV-1 plasma RNA viral load and immune activation among HIV-1 seropositive female workers in Abidjan, Côte d'Ivoire.
  Adjé CA, Bilé CE, Kestens L, Koblavi-Deme S, Ghys PD, Maurice C, Kalou-Badirou M, Kabran N, Ekpini RE, Roels TH, Wiktor SZ, Nkengasong JN
  J Med Virol. 2001
  PubMed ID: 11468722
   
  
• RANTES-induced chemokine cascade in dendritic cells.
  Fischer FR, Luo Y, Luo M, Santambrogio L, Dorf ME
  J Immunol. 2001
  PubMed ID: 11466387
   
  
• Polymorphism of CCR5 affecting HIV disease progression in the Japanese population.
  Kageyama S, Mimaya J, Yamada K, Kurimura T, Shiraki K, Research Committee on Prevention of Developing Illness and Therapy for HIV-infected People
  AIDS Res Hum Retroviruses. 2001
  PubMed ID: 11485615
   
  
• Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis.
  Peters W, Scott HM, Chambers HF, Flynn JL, Charo IF, Ernst JD
  Proc Natl Acad Sci U S A. 2001
  PubMed ID: 11438742
   
  
• Genetic variation at the chemokine receptors CCR5/CCR2 in myocardial infarction.
  González P, Alvarez R, Batalla A, Reguero JR, Alvarez V, Astudillo A, Cubero GI, Cortina A, Coto E
  Genes Immun. 2001
  PubMed ID: 11477473
   
  
• A multiethnic study of Delta32ccr5 and ccr2b-V64I allele distribution in four Los Angeles populations.
  Iyer RK, Kim PS, Bando JM, Lu KV, Gregg JP, Grody WW
  Diagn Mol Pathol. 2001
  PubMed ID: 11385319
   
  
• Polymorphism of CC chemokine receptors CCR2 and CCR5 in Crohn's disease.
  Herfarth H, Pollok-Kopp B, Göke M, Press A, Oppermann M
  Immunol Lett. 2001
  PubMed ID: 11377705
   
  
• Chemokine receptor homo- or heterodimerization activates distinct signaling pathways.
  Mellado M, Rodríguez-Frade JM, Vila-Coro AJ, Fernández S, Martín de Ana A, Jones DR, Torán JL, Martínez-A C
  EMBO J. 2001
  PubMed ID: 11350939
   
  
• Enhanced airway Th2 response after allergen challenge in mice deficient in CC chemokine receptor-2 (CCR2).
  Kim Y, Sung Ss, Kuziel WA, Feldman S, Fu SM, Rose CE
  J Immunol. 2001
  PubMed ID: 11290802
   
  
• Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5.
  Ogilvie P, Bardi G, Clark-Lewis I, Baggiolini M, Uguccioni M
  Blood. 2001
  PubMed ID: 11264152
   
  
• The sequence of the human genome.
  Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X
  Science. 2001
  PubMed ID: 11181995
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• A study on the density and distribution of uterine Natural Killer cells at mid pregnancy in mice genetically-ablated for CCR2, CCR 5 and the CCR5 receptor ligand, MIP-1 alpha.
  Chantakru S, Kuziel WA, Maeda N, Croy BA
  J Reprod Immunol. 2001
  PubMed ID: 11137111
   
  
• Basophil responses to chemokines are regulated by both sequential and cooperative receptor signaling.
  Heinemann A, Hartnell A, Stubbs VE, Murakami K, Soler D, LaRosa G, Askenase PW, Williams TJ, Sabroe I
  J Immunol. 2000
  PubMed ID: 11120855
   
  
• A mechanism for the impaired IFN-gamma production in C-C chemokine receptor 2 (CCR2) knockout mice: role of CCR2 in linking the innate and adaptive immune responses.
  Peters W, Dupuis M, Charo IF
  J Immunol. 2000
  PubMed ID: 11120836
   
  
• [Polymorphisms of chemokine receptor alleles influencing genetic susceptibility to HIV-1 infection in Mongolia population in China]
  Du Q, Wang F, Hong W, Liu M, Jin L, Shi H, Lei Z, E E
  Zhonghua Liu Xing Bing Xue Za Zhi. 2000
  PubMed ID: 11860823
   
  
• Distribution of three HIV-1 resistance-conferring polymorphisms (SDF1-3'A, CCR2-641, and CCR5-delta32) in global populations.
  Su B, Sun G, Lu D, Xiao J, Hu F, Chakraborty R, Deka R, Jin L
  Eur J Hum Genet. 2000
  PubMed ID: 11175286
   
  
• Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia.
  van der Meer P, Ulrich AM, Gonźalez-Scarano F, Lavi E
  Exp Mol Pathol. 2000
  PubMed ID: 11115360
   
  
• CC chemokine receptor-2 is not essential for the development of antigen-induced pulmonary eosinophilia and airway hyperresponsiveness.
  MacLean JA, De Sanctis GT, Ackerman KG, Drazen JM, Sauty A, DeHaan E, Green FH, Charo IF, Luster AD
  J Immunol. 2000
  PubMed ID: 11086100
   
  
• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
  Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
  Genome Res. 2000
  PubMed ID: 11076861
   
  
• Monocyte chemotactic protein-1 receptor CCR2B is a glycoprotein that has tyrosine sulfation in a conserved extracellular N-terminal region.
  Preobrazhensky AA, Dragan S, Kawano T, Gavrilin MA, Gulina IV, Chakravarty L, Kolattukudy PE
  J Immunol. 2000
  PubMed ID: 11046064
   
  
• CCR2-64I polymorphism, syncytium-inducing human immunodeficiency virus strains, and disease progression.
  Vicenzi E, Ghezzi S, Brambilla A, Sheppard HW, Lazzarin A, Poli G, Michael NL
  J Infect Dis. 2000
  PubMed ID: 11023492
   
  
• The chemokine receptor CCR2 is involved in macrophage recruitment to the injured peripheral nervous system.
  Siebert H, Sachse A, Kuziel WA, Maeda N, Brück W
  J Neuroimmunol. 2000
  PubMed ID: 11024548
   
  
• Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.
  Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD
  J Exp Med. 2000
  PubMed ID: 11015448
   
  
• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
  Genome Res. 2000
  PubMed ID: 11042159
   
  
• CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis.
  Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ
  J Exp Med. 2000
  PubMed ID: 10993920
   
  
• The level of HIV infection of macrophages is determined by interaction of viral and host cell genotypes.
  Cunningham AL, Li S, Juarez J, Lynch G, Alali M, Naif H
  J Leukoc Biol. 2000
  PubMed ID: 10985245
   
  
• Enhanced pulmonary allergic responses to Aspergillus in CCR2-/- mice.
  Blease K, Mehrad B, Standiford TJ, Lukacs NW, Gosling J, Boring L, Charo IF, Kunkel SL, Hogaboam CM
  J Immunol. 2000
  PubMed ID: 10946288
   
  
• [Distribution of HIV resistance CCR5-delta 32, CCR2-64 I and SDF1-3'A alleles and their polymorphisms in the Han population in China]
  Wang F, Jin L, Lei Z, Shi H, Hong W, Xu D, Shi M, Jiang J, Wang Y, Zhang B, Liu M, Li Y
  Zhonghua Liu Xing Bing Xue Za Zhi. 2000
  PubMed ID: 11860793
   
  
• Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells.
  Zhang Y, Lou B, Lal RB, Gettie A, Marx PA, Moore JP
  J Virol. 2000
  PubMed ID: 10888629
   
  
• CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokin
  Sato N, Ahuja SK, Quinones M, Kostecki V, Reddick RL, Melby PC, Kuziel WA, Ahuja SS
  J Exp Med. 2000
  PubMed ID: 10899907
   
  
• CCR2+ and CCR5+ CD8+ T cells increase during viral infection and migrate to sites of infection.
  Nansen A, Marker O, Bartholdy C, Thomsen AR
  Eur J Immunol. 2000
  PubMed ID: 10940868
   
  
• Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine.
  Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker HC
  J Immunol. 2000
  PubMed ID: 10843684
   
  
• Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus.
  Dawson TC, Beck MA, Kuziel WA, Henderson F, Maeda N
  Am J Pathol. 2000
  PubMed ID: 10854218
   
  
• Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women. European Network for In Utero Transmission of HIV-1.
  Tscherning-Casper C, Vödrös D, Menu E, Aperia K, Fredriksson R, Dolcini G, Chaouat G, Barré-Sinoussi F, Albert J, Fenyö EM
  J Acquir Immune Defic Syndr. 2000
  PubMed ID: 10877489
   
  
• Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation.
  McManus CM, Weidenheim K, Woodman SE, Nunez J, Hesselgesser J, Nath A, Berman JW
  Am J Pathol. 2000
  PubMed ID: 10751368
   
  
• Exaggerated hepatic injury due to acetaminophen challenge in mice lacking C-C chemokine receptor 2.
  Hogaboam CM, Bone-Larson CL, Steinhauser ML, Matsukawa A, Gosling J, Boring L, Charo IF, Simpson KJ, Lukacs NW, Kunkel SL
  Am J Pathol. 2000
  PubMed ID: 10751350
   
  
• Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation.
  Agace WW, Roberts AI, Wu L, Greineder C, Ebert EC, Parker CM
  Eur J Immunol. 2000
  PubMed ID: 10741397
   
  
• Dual renin gene targeting by Cre-mediated interchromosomal recombination.
  Matsusaka T, Kon V, Takaya J, Katori H, Chen X, Miyazaki J, Homma T, Fogo A, Ichikawa I
  Genomics. 2000
  PubMed ID: 10729219
   
  
• CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection.
  Traynor TR, Kuziel WA, Toews GB, Huffnagle GB
  J Immunol. 2000
  PubMed ID: 10657654
   
  
• Provincial distribution of three HIV-1 resistant polymorphisms (CCR5-Delta32, CCR2-64I, and SDF1-3' A) in China.
  Xiao J, Hu F, Xu H, Su B, Jiang Y, Luo J, Zhang W, Tan J, Jin L, Lu D
  Sci China C Life Sci. 2000
  PubMed ID: 18763111
   
  
• Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma.
  Sica A, Saccani A, Bottazzi B, Bernasconi S, Allavena P, Gaetano B, Fei F, LaRosa G, Scotton C, Balkwill F, Mantovani A
  J Immunol. 2000
  PubMed ID: 10623817
   
  
• Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice.
  Sato N, Kuziel WA, Melby PC, Reddick RL, Kostecki V, Zhao W, Maeda N, Ahuja SK, Ahuja SS
  J Immunol. 1999
  PubMed ID: 10553079
   
  
• Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2.
  Hemmerich S, Paavola C, Bloom A, Bhakta S, Freedman R, Grunberger D, Krstenansky J, Lee S, McCarley D, Mulkins M, Wong B, Pease J, Mizoue L, Mirzadegan T, Polsky I, Thompson K, Handel TM, Jarnagin K
  Biochemistry. 1999
  PubMed ID: 10529171
   
  
• Distribution of two HIV-1-resistant polymorphisms (SDF1-3'A and CCR2-64I) in East Asian and world populations and its implication in AIDS epidemiology.
  Su B, Jin L, Hu F, Xiao J, Luo J, Lu D, Zhang W, Chu J, Du R, Geng Z, Qiu X, Xue J, Tan J, O'Brien SJ, Chakraborty R
  Am J Hum Genet. 1999
  PubMed ID: 10486323
   
  
• Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.
  McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J
  Dev Biol. 1999
  PubMed ID: 10479460
   
  
• Expression of CCR2 by endothelial cells : implications for MCP-1 mediated wound injury repair and In vivo inflammatory activation of endothelium.
  Weber KS, Nelson PJ, Gröne HJ, Weber C
  Arterioscler Thromb Vasc Biol. 1999
  PubMed ID: 10479649
   
  
• Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2-/- mice: the role of mast cells.
  Campbell EM, Charo IF, Kunkel SL, Strieter RM, Boring L, Gosling J, Lukacs NW
  J Immunol. 1999
  PubMed ID: 10438957
   
  
• Effect of C-C chemokine receptor 2 (CCR2) knockout on type-2 (schistosomal antigen-elicited) pulmonary granuloma formation: analysis of cellular recruitment and cytokine responses.
  Warmington KS, Boring L, Ruth JH, Sonstein J, Hogaboam CM, Curtis JL, Kunkel SL, Charo IR, Chensue SW
  Am J Pathol. 1999
  PubMed ID: 10329593
   
  
• Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling.
  Rabin RL, Park MK, Liao F, Swofford R, Stephany D, Farber JM
  J Immunol. 1999
  PubMed ID: 10201901
   
  
• Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice.
  Dawson TC, Kuziel WA, Osahar TA, Maeda N
  Atherosclerosis. 1999
  PubMed ID: 10208497
   
  
• Characterization of the signal transduction pathway activated in human monocytes and dendritic cells by MPIF-1, a specific ligand for CC chemokine receptor 1.
  Nardelli B, Tiffany HL, Bong GW, Yourey PA, Morahan DK, Li Y, Murphy PM, Alderson RF
  J Immunol. 1999
  PubMed ID: 9886417
   
  
• High-efficiency full-length cDNA cloning.
  Carninci P, Hayashizaki Y
  Methods Enzymol. 1999
  PubMed ID: 10349636
   
  
• HIV-1 Tat protein mimicry of chemokines.
  Albini A, Ferrini S, Benelli R, Sforzini S, Giunciuglio D, Aluigi MG, Proudfoot AE, Alouani S, Wells TN, Mariani G, Rabin RL, Farber JM, Noonan DM
  Proc Natl Acad Sci U S A. 1998
  PubMed ID: 9789057
   
  
• HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors.
  Hoffman TL, Stephens EB, Narayan O, Doms RW
  Proc Natl Acad Sci U S A. 1998
  PubMed ID: 9736741
   
  
• Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis.
  Boring L, Gosling J, Cleary M, Charo IF
  Nature. 1998
  PubMed ID: 9732872
   
  
• Tumor-driven matrix invasion by infiltrating lymphocytes: involvement of the alpha1 integrin I-domain.
  Ferrero E, Fabbri M, Poggi A, Galati G, Bernasconi S, Zocchi MR
  Eur J Immunol. 1998
  PubMed ID: 9710230
   
  
• The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.
  Mellado M, Rodríguez-Frade JM, Aragay A, del Real G, Martín AM, Vila-Coro AJ, Serrano A, Mayor F, Martínez-A C
  J Immunol. 1998
  PubMed ID: 9670957
   
  
• Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression.
  Mummidi S, Ahuja SS, Gonzalez E, Anderson SA, Santiago EN, Stephan KT, Craig FE, O'Connell P, Tryon V, Clark RA, Dolan MJ, Ahuja SK
  Nat Med. 1998
  PubMed ID: 9662369
   
  
• Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis.
  Jiang Y, Salafranca MN, Adhikari S, Xia Y, Feng L, Sonntag MK, deFiebre CM, Pennell NA, Streit WJ, Harrison JK
  J Neuroimmunol. 1998
  PubMed ID: 9655467
   
  
• Structural interactions between chemokine receptors, gp120 Env and CD4.
  Choe H, Martin KA, Farzan M, Sodroski J, Gerard NP, Gerard C
  Semin Immunol. 1998
  PubMed ID: 9653051
   
  
• Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2.
  Aragay AM, Mellado M, Frade JM, Martin AM, Jimenez-Sainz MC, Martinez-A C, Mayor F
  Proc Natl Acad Sci U S A. 1998
  PubMed ID: 9501202
   
  
• Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells.
  Frade JM, Mellado M, del Real G, Gutierrez-Ramos JC, Lind P, Martinez-A C
  J Immunol. 1997
  PubMed ID: 9548499
   
  
• Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor.
  Kurihara T, Warr G, Loy J, Bravo R
  J Exp Med. 1997
  PubMed ID: 9362535
   
  
• Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.
  Boring L, Gosling J, Chensue SW, Kunkel SL, Farese RV, Broxmeyer HE, Charo IF
  J Clin Invest. 1997
  PubMed ID: 9366570
   
  
• Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.
  Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N
  Proc Natl Acad Sci U S A. 1997
  PubMed ID: 9342361
   
  
• The amino-terminal domain of CCR2 is both necessary and sufficient for high affinity binding of monocyte chemoattractant protein 1. Receptor activation by a pseudo-tethered ligand.
  Monteclaro FS, Charo IF
  J Biol Chem. 1997
  PubMed ID: 9287323
   
  
• Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort
  Smith MW, Dean M, Carrington M, Winkler C, Huttley GA, Lomb DA, Goedert JJ, O'Brien TR, Jacobson LP, Kaslow R, Buchbinder S, Vittinghoff E, Vlahov D, Hoots K, Hilgartner MW, O'Brien SJ
  Science. 1997
  PubMed ID: 9252328
   
  
• MCP-1 and CCR2 in HIV infection: regulation of agonist and receptor expression.
  Sozzani S, Introna M, Bernasconi S, Polentarutti N, Cinque P, Poli G, Sica A, Mantovani A
  J Leukoc Biol. 1997
  PubMed ID: 9225989
   
  
• Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B.
  Berkhout TA, Sarau HM, Moores K, White JR, Elshourbagy N, Appelbaum E, Reape RJ, Brawner M, Makwana J, Foley JJ, Schmidt DB, Imburgia C, McNulty D, Matthews J, O'Donnell K, O'Shannessy D, Scott M, Groot PH, Macphee C
  J Biol Chem. 1997
  PubMed ID: 9195948
   
  
• Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5.
  Nibbs RJ, Wylie SM, Pragnell IB, Graham GJ
  J Biol Chem. 1997
  PubMed ID: 9139699
   
  
• Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors.
  Gong X, Gong W, Kuhns DB, Ben-Baruch A, Howard OM, Wang JM
  J Biol Chem. 1997
  PubMed ID: 9115216
   
  
• The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster within 285 kb on human chromosome 3p21.
  Daugherty BL, Springer MS
  Genomics. 1997
  PubMed ID: 9143512
   
  
• IL-2-regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: characterization of a predominant 3.4-kilobase transcript containing CCR2B and CCR2A sequences.
  Polentarutti N, Allavena P, Bianchi G, Giardina G, Basile A, Sozzani S, Mantovani A, Introna M
  J Immunol. 1997
  PubMed ID: 9058802
   
  
• Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking.
  Wong LM, Myers SJ, Tsou CL, Gosling J, Arai H, Charo IF
  J Biol Chem. 1997
  PubMed ID: 8995400
   
  
• Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.
  Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF, Luster AD
  J Exp Med. 1997
  PubMed ID: 8996246
   
  
• The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3.
  Samson M, Soularue P, Vassart G, Parmentier M
  Genomics. 1996
  PubMed ID: 8884276
   
  
• Mouse astrocytes respond to the chemokines MCP-1 and KC, but reverse transcriptase-polymerase chain reaction does not detect mRNA for the KC or new MCP-1 receptor.
  Heesen M, Tanabe S, Berman MA, Yoshizawa I, Luo Y, Kim RJ, Post TW, Gerard C, Dorf ME
  J Neurosci Res. 1996
  PubMed ID: 8872898
   
  
• Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC.
  Kurihara T, Bravo R
  J Biol Chem. 1996
  PubMed ID: 8662823
   
  
• Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9.
  Boring L, Gosling J, Monteclaro FS, Lusis AJ, Tsou CL, Charo IF
  J Biol Chem. 1996
  PubMed ID: 8631787
   
  
• Monocyte chemoattractant protein-3 is a functional ligand for CC chemokine receptors 1 and 2B.
  Combadiere C, Ahuja SK, Van Damme J, Tiffany HL, Gao JL, Murphy PM
  J Biol Chem. 1995
  PubMed ID: 8530354
   
  
• Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9.
  Kozak CA, Gao JL, Murphy PM
  Genomics. 1995
  PubMed ID: 8530091
   
  
• cDNA cloning and functional expression of a human monocyte chemoattractant protein 1 receptor.
  Yamagami S, Tokuda Y, Ishii K, Tanaka H, Endo N
  Biochem Biophys Res Commun. 1994
  PubMed ID: 8048929
   
  
• Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
  Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR
  Proc Natl Acad Sci U S A. 1994
  PubMed ID: 8146186
   
  
• Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.
  Itoh H, Toyama R, Kozasa T, Tsukamoto T, Matsuoka M, Kaziro Y
  J Biol Chem. 1988
  PubMed ID: 2834384
   
  

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