TRB@

Summary Top Help

Gene Description:

T cell receptor beta chain; T cell receptor beta locus

Synonyms:

TRB, TCRbeta, TCRB, Tcrb, Tib, TRB@

Orthologs:

Human TRB@ (protein-coding), Mouse Tcrb (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for TRB@:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: We do not have expression data for this gene.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas
					no data	no data	no data	no data	no data	no data	no data	no data

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: We do not have tissue expression data for this gene.

Interactions Top Help

Interactions Table for TRB@:

Cross-Reference to Pathways and GO Terms Top Help

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: None available

Publications from PubMed Top Help

Type 1 Diabetes Publications: 21

Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice.
Feng N, Vegh P, Rothenberg EV, Yui MA
J Immunol. 2011
PubMed ID: 21148803
Autoreactive T-cell receptor (Vbeta/D/Jbeta) sequences in diabetes are homologous to insulin, glucagon, the insulin receptor, and the glucagon receptor.
Root-Bernstein R
J Mol Recognit. 2008
PubMed ID: 19051206
Mechanisms of PDL1-mediated regulation of autoimmune diabetes.
Guleria I, Gubbels Bupp M, Dada S, Fife B, Tang Q, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P, Yagita H, Azuma M, Atkinson M, Bluestone JA, Sayegh MH
Clin Immunol. 2007
PubMed ID: 17627890
Where CD4+CD25+ T reg cells impinge on autoimmune diabetes.
Chen Z, Herman AE, Matos M, Mathis D, Benoist C
J Exp Med. 2005
PubMed ID: 16301745
CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer.
Tarbell KV, Lee M, Ranheim E, Chao CC, Sanna M, Kim SK, Dickie P, Teyton L, Davis M, McDevitt H
J Exp Med. 2002
PubMed ID: 12186840
Restricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice.
Baker FJ, Lee M, Chien YH, Davis MM
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12082183
T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes.
Thiessen S, Serra P, Amrani A, Verdaguer J, Santamaria P
Diabetes. 2002
PubMed ID: 11812739
The level of peptide-MHC complex determines the susceptibility to autoimmune diabetes: studies in HEL transgenic mice.
DiPaolo RJ, Unanue ER
Eur J Immunol. 2001
PubMed ID: 11745364
Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.
Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S
Diabetes. 2001
PubMed ID: 11522664
Alpha beta TCR+ cells are a minimal fraction of peripheral CD8+ pool in MHC class I-deficient mice.
Nesić D, Santori FR, Vukmanović S
J Immunol. 2000
PubMed ID: 10925270
IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes.
Amrani A, Verdaguer J, Thiessen S, Bou S, Santamaria P
J Clin Invest. 2000
PubMed ID: 10683375
Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development.
Wilson A, Capone M, MacDonald HR
Int Immunol. 1999
PubMed ID: 10508182
Germinal center formation in mice lacking alpha beta T cells.
Dianda L, Gulbranson-Judge A, Pao W, Hayday AC, MacLennan IC, Owen MJ
Eur J Immunol. 1996
PubMed ID: 8766567
Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location.
Hess J, Ladel C, Miko D, Kaufmann SH
J Immunol. 1996
PubMed ID: 8617956
Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver.
Ohteki T, MacDonald HR
J Exp Med. 1996
PubMed ID: 8642272
Monoclonal T cells identified in early NOD islet infiltrates.
Yang Y, Charlton B, Shimada A, Dal Canto R, Fathman CG
Immunity. 1996
PubMed ID: 8624809
Immune responsiveness in mutant mice lacking T-cell receptor alpha beta+ cells.
Chandler P, Frater AJ, Douek DC, Viney JL, Kay G, Owen MJ, Hayday AC, Simpson E, Altmann DM
Immunology. 1995
PubMed ID: 7558145
T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice.
Hughes DP, Hayday A, Craft JE, Owen MJ, Crispe IN
J Exp Med. 1995
PubMed ID: 7540652
Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.
Förster I, Hirose R, Arbeit JM, Clausen BE, Hanahan D
Immunity. 1995
PubMed ID: 7796292
Functional analysis of the TCR alpha- beta+ cells that accumulate in the pneumonic lung of influenza virus-infected TCR-alpha-/- mice.
Eichelberger M, McMickle A, Blackman M, Mombaerts P, Tonegawa S, Doherty PC
J Immunol. 1995
PubMed ID: 7836742
Multiple TCR V beta usage by infiltrates of young NOD mouse islets of Langerhans. A polymerase chain reaction analysis.
Waters SH, O'Neil JJ, Melican DT, Appel MC
Diabetes. 1992
PubMed ID: 1372574

Publications: 611

Natural killer cells act as rheostats modulating antiviral T cells.
Waggoner SN, Cornberg M, Selin LK, Welsh RM
Nature. 2012
PubMed ID: 22101430
Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles.
Kiss EA, Vonarbourg C, Kopfmann S, Hobeika E, Finke D, Esser C, Diefenbach A
Science. 2011
PubMed ID: 22033518
Cutting edge: loss of α4 integrin expression differentially affects the homing of Th1 and Th17 cells.
Glatigny S, Duhen R, Oukka M, Bettelli E
J Immunol. 2011
PubMed ID: 22084440
The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy.
Strid J, Sobolev O, Zafirova B, Polic B, Hayday A
Science. 2011
PubMed ID: 22144628
Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism.
Scott DR, Borbulevych OY, Piepenbrink KH, Corcelli SA, Baker BM
J Mol Biol. 2011
PubMed ID: 22019736
Critical roles of RasGRP1 for invariant NKT cell development.
Shen S, Chen Y, Gorentla BK, Lu J, Stone JC, Zhong XP
J Immunol. 2011
PubMed ID: 21957144
Mitochondria as a sequestration site for incomplete TCRβ peptides: the TCRβ transmembrane domain is a sufficient mitochondrial targeting signal.
Shani N, Shinder V, Zipori D
Mol Immunol. 2011
PubMed ID: 21943707
IL-7 is required for the development of the intrinsic function of marginal zone B cells and the marginal zone microenvironment.
Willems L, Li S, Rutgeerts O, Lenaerts C, Waer M, Billiau AD
J Immunol. 2011
PubMed ID: 21873520
Pathogenic role of B cells in the development of diffuse alveolar hemorrhage induced by pristane.
Barker TT, Lee PY, Kelly-Scumpia KM, Weinstein JS, Nacionales DC, Kumagai Y, Akira S, Croker BP, Sobel ES, Reeves WH, Satoh M
Lab Invest. 2011
PubMed ID: 21808234
Development and function of innate polyclonal TCRalphabeta+ CD8+ thymocytes.
Rafei M, Hardy MP, Williams P, Vanegas JR, Forner KA, Dulude G, Labrecque N, Galipeau J, Perreault C
J Immunol. 2011
PubMed ID: 21844388
Differential regulation of proximal and distal Vbeta segments upstream of a functional VDJbeta1 rearrangement upon beta-selection.
Brady BL, Bassing CH
J Immunol. 2011
PubMed ID: 21844384
Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint.
Saba I, Kosan C, Vassen L, Klein-Hitpass L, Möröy T
J Immunol. 2011
PubMed ID: 21841135
Physiologic control of IDO competence in splenic dendritic cells.
Baban B, Chandler PR, Johnson BA, Huang L, Li M, Sharpe ML, Francisco LM, Sharpe AH, Blazar BR, Munn DH, Mellor AL
J Immunol. 2011
PubMed ID: 21813777
Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies.
Li F, Ravetch JV
Science. 2011
PubMed ID: 21852502
Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked antileukemia reactivity and safety.
Ochi T, Fujiwara H, Okamoto S, An J, Nagai K, Shirakata T, Mineno J, Kuzushima K, Shiku H, Yasukawa M
Blood. 2011
PubMed ID: 21673345
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions.
Chung Y, Tanaka S, Chu F, Nurieva RI, Martinez GJ, Rawal S, Wang YH, Lim H, Reynolds JM, Zhou XH, Fan HM, Liu ZM, Neelapu SS, Dong C
Nat Med. 2011
PubMed ID: 21785430
B cells enhance early innate immune responses during bacterial sepsis.
Kelly-Scumpia KM, Scumpia PO, Weinstein JS, Delano MJ, Cuenca AG, Nacionales DC, Wynn JL, Lee PY, Kumagai Y, Efron PA, Akira S, Wasserfall C, Atkinson MA, Moldawer LL
J Exp Med. 2011
PubMed ID: 21746813
Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.
Shibata K, Yamada H, Sato T, Dejima T, Nakamura M, Ikawa T, Hara H, Yamasaki S, Kageyama R, Iwakura Y, Kawamoto H, Toh H, Yoshikai Y
Blood. 2011
PubMed ID: 21606479
Clonally related CD8+ T cells responsible for rapid population of both diffuse nasal-associated lymphoid tissue and lung after respiratory virus infection.
Surman SL, Rudraraju R, Woodland DL, Dash P, Thomas PG, Hurwitz JL
J Immunol. 2011
PubMed ID: 21690324
A self-reactive TCR drives the development of Foxp3+ regulatory T cells that prevent autoimmune disease.
Killebrew JR, Perdue N, Kwan A, Thornton AM, Shevach EM, Campbell DJ
J Immunol. 2011
PubMed ID: 21690323
Physical and functional bivalency observed among TCR/CD3 complexes isolated from primary T cells.
Schrum AG, Gil D, Turka LA, Palmer E
J Immunol. 2011
PubMed ID: 21666056
Absence of TCR loci chromosomal translocations in cutaneous T-cell lymphomas.
Salgado R, Gallardo F, Servitje O, Estrach T, García-Muret MP, Romagosa V, Florensa L, Serrano S, Salido M, Solé F, Pujol RM, Espinet B
Cancer Genet. 2011
PubMed ID: 21872828
The development of inducible bronchus-associated lymphoid tissue depends on IL-17.
Rangel-Moreno J, Carragher DM, de la Luz Garcia-Hernandez M, Hwang JY, Kusser K, Hartson L, Kolls JK, Khader SA, Randall TD
Nat Immunol. 2011
PubMed ID: 21666689
TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells.
Orlando L, Accomasso L, Circosta P, Turinetto V, Lantelme E, Porcedda P, Minieri V, Pautasso M, Willemsen RA, Cignetti A, Giachino C
Mol Immunol. 2011
PubMed ID: 21481940
Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses.
Day EB, Guillonneau C, Gras S, La Gruta NL, Vignali DA, Doherty PC, Purcell AW, Rossjohn J, Turner SJ
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21606376
Th17 cells induce colitis and promote Th1 cell responses through IL-17 induction of innate IL-12 and IL-23 production.
Feng T, Qin H, Wang L, Benveniste EN, Elson CO, Cong Y
J Immunol. 2011
PubMed ID: 21531892
The C-terminally encoded, MHC class II-restricted T cell antigenicity of the Helicobacter pylori virulence factor CagA promotes gastric preneoplasia.
Arnold IC, Hitzler I, Engler D, Oertli M, Agger EM, Müller A
J Immunol. 2011
PubMed ID: 21518972
Presynaptic impairment in Niemann-Pick C1-deficient neurons: not dependent on presence of glial cells.
Xu S, Chen X, Wei X, Liu G, Wang Q
Neurosci Lett. 2011
PubMed ID: 21507342
Change in expression pattern of TCR-CD3 complex in patients with multiple myeloma.
Li Y, Chen S, Yang L, Chen S, Lin C, Wang L, Lu Y, Geng S, Du X, Schmidt CA
Hematology. 2011
PubMed ID: 21669053
Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t.
Ripen AM, Nitta T, Murata S, Tanaka K, Takahama Y
Eur J Immunol. 2011
PubMed ID: 21469133
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells.
Motomura Y, Kitamura H, Hijikata A, Matsunaga Y, Matsumoto K, Inoue H, Atarashi K, Hori S, Watarai H, Zhu J, Taniguchi M, Kubo M
Nat Immunol. 2011
PubMed ID: 21460847
Cutting edge: Generation of colitogenic Th17 CD4 T cells is enhanced by IL-17+ γδ T cells.
Do JS, Visperas A, Dong C, Baldwin WM, Min B
J Immunol. 2011
PubMed ID: 21402889
Cardiolipin binds to CD1d and stimulates CD1d-restricted γδ T cells in the normal murine repertoire.
Dieudé M, Striegl H, Tyznik AJ, Wang J, Behar SM, Piccirillo CA, Levine JS, Zajonc DM, Rauch J
J Immunol. 2011
PubMed ID: 21389252
A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing.
Venturi V, Quigley MF, Greenaway HY, Ng PC, Ende ZS, McIntosh T, Asher TE, Almeida JR, Levy S, Price DA, Davenport MP, Douek DC
J Immunol. 2011
PubMed ID: 21383244
Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool.
Houston EG, Higdon LE, Fink PJ
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21402911
A barrier-type insulator forms a boundary between active and inactive chromatin at the murine TCRβ locus.
Carabana J, Watanabe A, Hao B, Krangel MS
J Immunol. 2011
PubMed ID: 21317385
Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.
Ota T, Ota M, Duong BH, Gavin AL, Nemazee D
J Exp Med. 2011
PubMed ID: 21357741
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics.
Borbulevych OY, Piepenbrink KH, Baker BM
J Immunol. 2011
PubMed ID: 21282516
Intrinsic requirement for the vitamin D receptor in the development of CD8αα-expressing T cells.
Bruce D, Cantorna MT
J Immunol. 2011
PubMed ID: 21270396
In vivo 6-thioguanine-resistant T cells from melanoma patients have public TCR and share TCR beta amino acid sequences with melanoma-reactive T cells.
Zuleger CL, Macklin MD, Bostwick BL, Pei Q, Newton MA, Albertini MR
J Immunol Methods. 2011
PubMed ID: 21182840
Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction.
Tezuka H, Abe Y, Asano J, Sato T, Liu J, Iwata M, Ohteki T
Immunity. 2011
PubMed ID: 21333555
The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes.
Teng F, Zhou Y, Jin R, Chen Y, Pei X, Liu Y, Dong J, Wang W, Pang X, Qian X, Chen WF, Zhang Y, Ge Q
PLoS One. 2011
PubMed ID: 22022412
Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways in vivo.
Mahowald GK, Mahowald MA, Moon C, Khor B, Sleckman BP
PLoS One. 2011
PubMed ID: 21765899
The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.
Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ
PLoS One. 2011
PubMed ID: 21673984
Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation.
Wu X, Zhu K, Du X, Chen S, Yang L, Wu J, Liu Q, Li Y
J Hematol Oncol. 2011
PubMed ID: 21513557
Expression of the T cell receptor αβ on a CD123+ BDCA2+ HLA-DR+ subpopulation in head and neck squamous cell carcinoma.
Thiel A, Kesselring R, Pries R, Puzik A, Wittkopf N, Wollenberg B
PLoS One. 2011
PubMed ID: 21264308
Alloantibodies prevent the induction of transplantation tolerance by enhancing alloreactive T cell priming.
Burns AM, Chong AS
J Immunol. 2011
PubMed ID: 21135169
Evaluation of the immunoregulatory activity of intraepithelial lymphocytes in a mouse model of chronic intestinal inflammation.
Ostanin DV, Brown CM, Gray L, Bharwani S, Grisham MB
Int Immunol. 2010
PubMed ID: 21071622
Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype.
Moffat JM, Handel A, Doherty PC, Turner SJ, Thomas PG, La Gruta NL
J Immunol. 2010
PubMed ID: 21041725
Cutting edge: adaptive versus innate receptor signals selectively control the pool sizes of murine IFN-γ- or IL-17-producing γδ T cells upon infection.
Ribot JC, Chaves-Ferreira M, d'Orey F, Wencker M, Gonçalves-Sousa N, Decalf J, Simas JP, Hayday AC, Silva-Santos B
J Immunol. 2010
PubMed ID: 21037088
Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing γδ T cells.
Laird RM, Laky K, Hayes SM
J Immunol. 2010
PubMed ID: 20974990
Epigenetic control of Tcrb gene rearrangement.
Spicuglia S, Pekowska A, Zacarias-Cabeza J, Ferrier P
Semin Immunol. 2010
PubMed ID: 20829066
Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice.
Tiller T, Kofer J, Kreschel C, Busse CE, Riebel S, Wickert S, Oden F, Mertes MM, Ehlers M, Wardemann H
J Exp Med. 2010
PubMed ID: 21078890
Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for beta-selection and TCR repertoire formation.
Ishikawa E, Miyake Y, Hara H, Saito T, Yamasaki S
Proc Natl Acad Sci U S A. 2010
PubMed ID: 21030681
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.
Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20956329
Cutting edge: Thymic NK cells develop independently from T cell precursors.
Ribeiro VS, Hasan M, Wilson A, Boucontet L, Pereira P, Lesjean-Pottier S, Satoh-Takayama N, Di Santo JP, Vosshenrich CA
J Immunol. 2010
PubMed ID: 20889548
Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis.
Kasten KR, Prakash PS, Unsinger J, Goetzman HS, England LG, Cave CM, Seitz AP, Mazuski CN, Zhou TT, Morre M, Hotchkiss RS, Hildeman DA, Caldwell CC
Infect Immun. 2010
PubMed ID: 20823197
Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases.
Miletic AV, Anzelon-Mills AN, Mills DM, Omori SA, Pedersen IM, Shin DM, Ravetch JV, Bolland S, Morse HC, Rickert RC
J Exp Med. 2010
PubMed ID: 20956547
γδ T cells protect against lung fibrosis via IL-22.
Simonian PL, Wehrmann F, Roark CL, Born WK, O'Brien RL, Fontenot AP
J Exp Med. 2010
PubMed ID: 20855496
Restricted TCR-alpha CDR3 diversity disadvantages natural regulatory T cell development in the B6.2.16 beta-chain transgenic mouse.
Singh Y, Ferreira C, Chan AC, Dyson J, Garden OA
J Immunol. 2010
PubMed ID: 20713881
Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.
Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH
J Immunol. 2010
PubMed ID: 20709953
Combinations of affinity-enhancing mutations in a T cell receptor reveal highly nonadditive effects within and between complementarity determining regions and chains.
Pierce BG, Haidar JN, Yu Y, Weng Z
Biochemistry. 2010
PubMed ID: 20681514
Association between reduced copy-number at T-cell receptor gamma (TCRgamma) and childhood allergic asthma: A possible role for somatic mosaicism.
Walsh KM, Bracken MB, Murk WK, Hoh J, Dewan AT
Mutat Res. 2010
PubMed ID: 20553737
Naturally activated Vgamma4 gammadelta T cells play a protective role in tumor immunity through expression of eomesodermin.
He W, Hao J, Dong S, Gao Y, Tao J, Chi H, Flavell R, O'Brien RL, Born WK, Craft J, Han J, Wang P, Zhao L, Wu J, Yin Z
J Immunol. 2010
PubMed ID: 20525896
Transcription-dependent mobilization of nucleosomes at accessible TCR gene segments in vivo.
Kondilis-Mangum HD, Cobb RM, Osipovich O, Srivatsan S, Oltz EM, Krangel MS
J Immunol. 2010
PubMed ID: 20483751
Molecular analysis of tumor-promoting CD8+ T cells in two-stage cutaneous chemical carcinogenesis.
Kwong BY, Roberts SJ, Silberzahn T, Filler RB, Neustadter JH, Galan A, Reddy S, Lin WM, Ellis PD, Langford CF, Hayday AC, Girardi M
J Invest Dermatol. 2010
PubMed ID: 19924136
Induction of distinct neurologic disease manifestations during relapsing fever requires T lymphocytes.
Liu H, Fitzgerald D, Gran B, Leong JM, Alugupalli KR
J Immunol. 2010
PubMed ID: 20382883
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.
Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS
J Clin Invest. 2010
PubMed ID: 20364087
NK cells and gammadelta T cells mediate resistance to polyomavirus-induced tumors.
Mishra R, Chen AT, Welsh RM, Szomolanyi-Tsuda E
PLoS Pathog. 2010
PubMed ID: 20523894
Aberrant V(D)J cleavages in T cell receptor beta enhancer- and p53-deficient lymphoma cells.
Kang YH, Son CY, Lee CH, Ryu CJ
Oncol Rep. 2010
PubMed ID: 20372865
Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis.
Obata T, Goto Y, Kunisawa J, Sato S, Sakamoto M, Setoyama H, Matsuki T, Nonaka K, Shibata N, Gohda M, Kagiyama Y, Nochi T, Yuki Y, Fukuyama Y, Mukai A, Shinzaki S, Fujihashi K, Sasakawa C, Iijima H, Goto M, Umesaki Y, Benno Y, Kiyono H
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20360558
Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung.
Suzuki A, Iwamura C, Shinoda K, Tumes DJ, Kimura MY, Hosokawa H, Endo Y, Horiuchi S, Tokoyoda K, Koseki H, Yamashita M, Nakayama T
J Immunol. 2010
PubMed ID: 20237291
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.
Huang J, Zarnitsyna VI, Liu B, Edwards LJ, Jiang N, Evavold BD, Zhu C
Nature. 2010
PubMed ID: 20357766
Evidence for a functional sidedness to the alphabetaTCR.
Kuhns MS, Girvin AT, Klein LO, Chen R, Jensen KD, Newell EW, Huppa JB, Lillemeier BF, Huse M, Chien YH, Garcia KC, Davis MM
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20202921
Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.
Rudd BD, Venturi V, Smithey MJ, Way SS, Davenport MP, Nikolich-Zugich J
J Immunol. 2010
PubMed ID: 20164421
B-cell-derived lymphotoxin promotes castration-resistant prostate cancer.
Ammirante M, Luo JL, Grivennikov S, Nedospasov S, Karin M
Nature. 2010
PubMed ID: 20220849
Abnormalities of the alphabeta T-cell receptor repertoire in advanced myelodysplastic syndrome.
Campregher PV, Srivastava SK, Deeg HJ, Robins HS, Warren EH
Exp Hematol. 2010
PubMed ID: 20035823
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome.
Reimer T, Shaw MH, Franchi L, Coban C, Ishii KJ, Akira S, Horii T, Rodriguez A, Núñez G
Eur J Immunol. 2010
PubMed ID: 19950187
TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes.
Yang-Iott KS, Carpenter AC, Rowh MA, Steinel N, Brady BL, Hochedlinger K, Jaenisch R, Bassing CH
J Immunol. 2010
PubMed ID: 20042591
IL-10 induction by Bordetella parapertussis limits a protective IFN-gamma response.
Wolfe DN, Karanikas AT, Hester SE, Kennett MJ, Harvill ET
J Immunol. 2010
PubMed ID: 20042578
Identification of the transgenic integration site in immunodeficient tgε26 human CD3ε transgenic mice.
Ohigashi I, Yamasaki Y, Hirashima T, Takahama Y
PLoS One. 2010
PubMed ID: 21203507
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea.
Endt K, Stecher B, Chaffron S, Slack E, Tchitchek N, Benecke A, Van Maele L, Sirard JC, Mueller AJ, Heikenwalder M, Macpherson AJ, Strugnell R, von Mering C, Hardt WD
PLoS Pathog. 2010
PubMed ID: 20844578
Endogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection.
Montaudouin C, Boucontet L, Mailhé-Lembezat MP, Mariotti-Ferrandiz ME, Louise A, Six A, Freitas AA, Garcia S
PLoS One. 2010
PubMed ID: 20454452
Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites.
Weth O, Weth C, Bartkuhn M, Leers J, Uhle F, Renkawitz R
PLoS One. 2010
PubMed ID: 20404925
Duality of enhancer functioning mode revealed in a reduced TCR beta gene enhancer knockin mouse model.
Bonnet M, Huang F, Benoukraf T, Cabaud O, Verthuy C, Boucher A, Jaeger S, Ferrier P, Spicuglia S
J Immunol. 2009
PubMed ID: 19923469
Differential requirements of MHC and of DCs for endogenous proliferation of different T-cell subsets in vivo.
Do JS, Min B
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19920180
The alphabeta T cell receptor is an anisotropic mechanosensor.
Kim ST, Takeuchi K, Sun ZY, Touma M, Castro CE, Fahmy A, Lang MJ, Wagner G, Reinherz EL
J Biol Chem. 2009
PubMed ID: 19755427
Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells.
Robins HS, Campregher PV, Srivastava SK, Wacher A, Turtle CJ, Kahsai O, Riddell SR, Warren EH, Carlson CS
Blood. 2009
PubMed ID: 19706884
Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability.
Bao X, Pal R, Hascup KN, Wang Y, Wang WT, Xu W, Hui D, Agbas A, Wang X, Michaelis ML, Choi IY, Belousov AB, Gerhardt GA, Michaelis EK
J Neurosci. 2009
PubMed ID: 19890003
Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity.
Nagatake T, Fukuyama S, Kim DY, Goda K, Igarashi O, Sato S, Nochi T, Sagara H, Yokota Y, Jetten AM, Kaisho T, Akira S, Mimuro H, Sasakawa C, Fukui Y, Fujihashi K, Akiyama T, Inoue J, Penninger JM, Kunisawa J, Kiyono H
J Exp Med. 2009
PubMed ID: 19822644
Role of the immune modulator programmed cell death-1 during development and apoptosis of mouse retinal ganglion cells.
Chen L, Sham CW, Chan AM, Francisco LM, Wu Y, Mareninov S, Sharpe AH, Freeman GJ, Yang XJ, Braun J, Gordon LK
Invest Ophthalmol Vis Sci. 2009
PubMed ID: 19420345
An accessory role for B cells in the IL-12-induced activation of resting mouse NK cells.
Haddad EA, Senger LK, Takei F
J Immunol. 2009
PubMed ID: 19710462
T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling.
Terauchi M, Li JY, Bedi B, Baek KH, Tawfeek H, Galley S, Gilbert L, Nanes MS, Zayzafoon M, Guldberg R, Lamar DL, Singer MA, Lane TF, Kronenberg HM, Weitzmann MN, Pacifici R
Cell Metab. 2009
PubMed ID: 19723499
Promoter activity 5' of Dbeta2 is coordinated by E47, Runx1, and GATA-3.
McMillan RE, Sikes ML
Mol Immunol. 2009
PubMed ID: 19592096
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.
Yashiro-Ohtani Y, He Y, Ohtani T, Jones ME, Shestova O, Xu L, Fang TC, Chiang MY, Intlekofer AM, Blacklow SC, Zhuang Y, Pear WS
Genes Dev. 2009
PubMed ID: 19605688
The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin.
Huang Y, Jin N, Roark CL, Aydintug MK, Wands JM, Huang H, O'Brien RL, Born WK
J Immunol. 2009
PubMed ID: 19542369
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
Nature. 2009
PubMed ID: 19494813
Protective role of gammadelta T cells in spontaneous ocular inflammation.
O'Brien RL, Taylor MA, Hartley J, Nuhsbaum T, Dugan S, Lahmers K, Aydintug MK, Wands JM, Roark CL, Born WK
Invest Ophthalmol Vis Sci. 2009
PubMed ID: 19151391
IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and {gamma}{delta} T cells in vivo.
Do JS, Min B
Blood. 2009
PubMed ID: 19380870
The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response.
Gil-Cruz C, Bobat S, Marshall JL, Kingsley RA, Ross EA, Henderson IR, Leyton DL, Coughlan RE, Khan M, Jensen KT, Buckley CD, Dougan G, MacLennan IC, López-Macías C, Cunningham AF
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19487686
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation.
Koch MA, Tucker-Heard G, Perdue NR, Killebrew JR, Urdahl KB, Campbell DJ
Nat Immunol. 2009
PubMed ID: 19412181
Assembled DJ beta complexes influence TCR beta chain selection and peripheral V beta repertoire.
Carpenter AC, Yang-Iott KS, Chao LH, Nuskey B, Whitlow S, Alt FW, Bassing CH
J Immunol. 2009
PubMed ID: 19380806
Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis.
Ueda-Hayakawa I, Mahlios J, Zhuang Y
J Immunol. 2009
PubMed ID: 19380777
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection.
Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P
Nature. 2009
PubMed ID: 19262510
CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance.
Kurtz J, Raval F, Vallot C, Der J, Sykes M
Blood. 2009
PubMed ID: 19179471
Incomplete T-cell receptor-beta peptides target the mitochondrion and induce apoptosis.
Shani N, Rubin-Lifshitz H, Peretz-Cohen Y, Shkolnik K, Shinder V, Cohen-Sfady M, Shav-Tal Y, Barda-Saad M, Zipori D
Blood. 2009
PubMed ID: 18931338
Impaired antibody response causes persistence of prototypic T cell-contained virus.
Bergthaler A, Flatz L, Verschoor A, Hegazy AN, Holdener M, Fink K, Eschli B, Merkler D, Sommerstein R, Horvath E, Fernandez M, Fitsche A, Senn BM, Verbeek JS, Odermatt B, Siegrist CA, Pinschewer DD
PLoS Biol. 2009
PubMed ID: 19355789
B cell proliferation, somatic hypermutation, class switch recombination, and autoantibody production in ectopic lymphoid tissue in murine lupus.
Nacionales DC, Weinstein JS, Yan XJ, Albesiano E, Lee PY, Kelly-Scumpia KM, Lyons R, Satoh M, Chiorazzi N, Reeves WH
J Immunol. 2009
PubMed ID: 19299721
CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets.
Ribot JC, deBarros A, Pang DJ, Neves JF, Peperzak V, Roberts SJ, Girardi M, Borst J, Hayday AC, Pennington DJ, Silva-Santos B
Nat Immunol. 2009
PubMed ID: 19270712
Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness.
Matsubara S, Takeda K, Jin N, Okamoto M, Matsuda H, Shiraishi Y, Park JW, McConville G, Joetham A, O'Brien RL, Dakhama A, Born WK, Gelfand EW
Am J Respir Cell Mol Biol. 2009
PubMed ID: 18927346
An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells.
Van de Walle I, De Smet G, De Smedt M, Vandekerckhove B, Leclercq G, Plum J, Taghon T
Blood. 2009
PubMed ID: 19056690
The lymphotoxin LTalpha(1)beta(2) controls postnatal and adult spleen marginal sinus vascular structure and function.
Zindl CL, Kim TH, Zeng M, Archambault AS, Grayson MH, Choi K, Schreiber RD, Chaplin DD
Immunity. 2009
PubMed ID: 19303389
A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy.
Louvet C, Kabre BG, Davini DW, Martinier N, Su MA, DeVoss JJ, Rosenthal WL, Anderson MS, Bour-Jordan H, Bluestone JA
J Exp Med. 2009
PubMed ID: 19221395
Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin-17 production via programmed death 1.
Wang C, Dehghani B, Li Y, Kaler LJ, Vandenbark AA, Offner H
Immunology. 2009
PubMed ID: 19302141
B-cell co-receptor CD72 is expressed on NK cells and inhibits IFN-gamma production but not cytotoxicity.
Alcón VL, Luther C, Balce D, Takei F
Eur J Immunol. 2009
PubMed ID: 19197938
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis.
Conti HR, Shen F, Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hai JH, Yu JJ, Jung JW, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL
J Exp Med. 2009
PubMed ID: 19204111
CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance.
Friedline RH, Brown DS, Nguyen H, Kornfeld H, Lee J, Zhang Y, Appleby M, Der SD, Kang J, Chambers CA
J Exp Med. 2009
PubMed ID: 19188497
MyD88 intrinsically regulates CD4 T-cell responses.
Zhou S, Kurt-Jones EA, Cerny AM, Chan M, Bronson RT, Finberg RW
J Virol. 2009
PubMed ID: 19052080
T cell-derived lymphotoxin regulates liver regeneration.
Tumanov AV, Koroleva EP, Christiansen PA, Khan MA, Ruddy MJ, Burnette B, Papa S, Franzoso G, Nedospasov SA, Fu YX, Anders RA
Gastroenterology. 2009
PubMed ID: 18952083
Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking.
Kim JK, Klinger M, Benjamin J, Xiao Y, Erle DJ, Littman DR, Killeen N
PLoS One. 2009
PubMed ID: 19668367
Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells.
Victoratos P, Kollias G
Immunity. 2009
PubMed ID: 19119026
Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis.
Simonian PL, Roark CL, Wehrmann F, Lanham AK, Diaz del Valle F, Born WK, O'Brien RL, Fontenot AP
J Immunol. 2009
PubMed ID: 19109199
Alpha beta T cell receptor transfer to gamma delta T cells generates functional effector cells without mixed TCR dimers in vivo.
van der Veken LT, Coccoris M, Swart E, Falkenburg JH, Schumacher TN, Heemskerk MH
J Immunol. 2009
PubMed ID: 19109147
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.
Brochard V, Combadière B, Prigent A, Laouar Y, Perrin A, Beray-Berthat V, Bonduelle O, Alvarez-Fischer D, Callebert J, Launay JM, Duyckaerts C, Flavell RA, Hirsch EC, Hunot S
J Clin Invest. 2009
PubMed ID: 19104149
Functional overlap in the cis-acting regulation of the V(D)J recombination at the TCRbeta locus.
Khor B, Mahowald GK, Khor K, Sleckman BP
Mol Immunol. 2009
PubMed ID: 19070901
Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.
Fiorini E, Ferrero I, Merck E, Favre S, Pierres M, Luther SA, MacDonald HR
J Immunol. 2008
PubMed ID: 19050235
T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice.
Tsao PY, Jiao J, Ji MQ, Cohen PL, Eisenberg RA
J Immunol. 2008
PubMed ID: 19017966
TCR-beta chains derived from peripheral gammadelta T cells can take part in alphabeta T-cell development.
Bosco N, Engdahl C, Bénard A, Rolink J, Ceredig R, Rolink AG
Eur J Immunol. 2008
PubMed ID: 18991270
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.
Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, Vartanian TK, Brown RH, Carroll MC
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18997009
Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation.
Kim G, Turovskaya O, Levin M, Byrne FR, Whoriskey JS, McCabe JG, Kronenberg M
J Immunol. 2008
PubMed ID: 18832683
E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
Jia J, Dai M, Zhuang Y
Eur J Immunol. 2008
PubMed ID: 18958875
Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis.
Hao Z, Duncan GS, Seagal J, Su YW, Hong C, Haight J, Chen NJ, Elia A, Wakeham A, Li WY, Liepa J, Wood GA, Casola S, Rajewsky K, Mak TW
Immunity. 2008
PubMed ID: 18835195
Swift entry of myelin-specific T lymphocytes into the central nervous system in spontaneous autoimmune encephalomyelitis.
Furtado GC, Marcondes MC, Latkowski JA, Tsai J, Wensky A, Lafaille JJ
J Immunol. 2008
PubMed ID: 18802067
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells.
Wang L, Wildt KF, Zhu J, Zhang X, Feigenbaum L, Tessarollo L, Paul WE, Fowlkes BJ, Bosselut R
Nat Immunol. 2008
PubMed ID: 18776904
Different Allelic Distribution of a Single SNP Between Sexes in Humans.
Tripputi P, Cigognini D, Bianchi S, Fedele L
Biochem Genet. 2008
PubMed ID: 18777093
Nonredundant functions of alphabeta and gammadelta T cells in acrolein-induced pulmonary pathology.
Borchers MT, Wesselkamper SC, Eppert BL, Motz GT, Sartor MA, Tomlinson CR, Medvedovic M, Tichelaar JW
Toxicol Sci. 2008
PubMed ID: 18515264
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin a generation in the gut.
Tsuji M, Suzuki K, Kitamura H, Maruya M, Kinoshita K, Ivanov II, Itoh K, Littman DR, Fagarasan S
Immunity. 2008
PubMed ID: 18656387
Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis.
Elyaman W, Kivisäkk P, Reddy J, Chitnis T, Raddassi K, Imitola J, Bradshaw E, Kuchroo VK, Yagita H, Sayegh MH, Khoury SJ
Am J Pathol. 2008
PubMed ID: 18583313
Immune system derived from homeostatic proliferation generates normal CD8 T-cell memory but altered repertoires and diminished heterologous immune responses.
Lin SJ, Chen AT, Welsh RM
Blood. 2008
PubMed ID: 18509089
IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection.
McLoughlin RM, Lee JC, Kasper DL, Tzianabos AO
J Immunol. 2008
PubMed ID: 18606687
ICOS costimulation expands Th2 immunity by augmenting migration of lymphocytes to draining lymph nodes.
Tesciuba AG, Shilling RA, Agarwal MD, Bandukwala HS, Clay BS, Moore TV, Weinstock JV, Welcher AA, Sperling AI
J Immunol. 2008
PubMed ID: 18606653
Clonal CD8+ TCR-Vbeta expanded populations with effector memory phenotype in Churg Strauss syndrome.
Guida G, Vallario A, Stella S, Boita M, Circosta P, Mariani S, Prato G, Heffler E, Bergia R, Sottile A, Rolla G, Cignetti A
Clin Immunol. 2008
PubMed ID: 18502180
CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease.
Greidinger EL, Zang YJ, Jaimes K, Martinez L, Nassiri M, Hoffman RW
J Immunol. 2008
PubMed ID: 18523312
A unique B2 B cell subset in the intestine.
Shimomura Y, Ogawa A, Kawada M, Sugimoto K, Mizoguchi E, Shi HN, Pillai S, Bhan AK, Mizoguchi A
J Exp Med. 2008
PubMed ID: 18519649
Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice.
Kim S, Lalani S, Parekh VV, Vincent TL, Wu L, Van Kaer L
J Clin Invest. 2008
PubMed ID: 18451996
TCRBV20S1 and TCRBV3S1 Gene Segment Polymorphisms in Systemic Sclerosis.
Bredemeier M, Chies JA, Wieck A, Capobianco KG, Pitrez EH, Rohde LE, Pinotti AF, Brenol JC, Xavier RM
J Rheumatol. 2008
PubMed ID: 18412309
T-cell receptor Vbeta CDR3 oligoclonality frequently occurs in childhood refractory cytopenia (MDS-RC) and severe aplastic anemia.
de Vries AC, Langerak AW, Verhaaf B, Niemeyer CM, Stary J, Schmiegelow K, van Wering ER, Zwaan CM, Beishuizen A, Pieters R, van den Heuvel-Eibrink MM
Leukemia. 2008
PubMed ID: 18323803
Contribution of TCR-beta locus and HLA to the shape of the mature human Vbeta repertoire.
Melenhorst JJ, Lay MD, Price DA, Adams SD, Zeilah J, Sosa E, Hensel NF, Follmann D, Douek DC, Davenport MP, Barrett AJ
J Immunol. 2008
PubMed ID: 18453566
Protective immunosurveillance and therapeutic antitumor activity of gammadelta T cells demonstrated in a mouse model of prostate cancer.
Liu Z, Eltoum IE, Guo B, Beck BH, Cloud GA, Lopez RD
J Immunol. 2008
PubMed ID: 18424725
IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection.
Wilson DC, Matthews S, Yap GS
J Immunol. 2008
PubMed ID: 18424713
Down-modulation of TCR expression by Salmonella enterica serovar Typhimurium.
van der Velden AW, Dougherty JT, Starnbach MN
J Immunol. 2008
PubMed ID: 18390741
Itch-/- alphabeta and gammadelta T cells independently contribute to autoimmunity in Itchy mice.
Parravicini V, Field AC, Tomlinson PD, Basson MA, Zamoyska R
Blood. 2008
PubMed ID: 18256323
Unique subset of natural killer cells develops from progenitors in lymph node.
Veinotte LL, Halim TY, Takei F
Blood. 2008
PubMed ID: 18227350
A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.
Wun KS, Borg NA, Kjer-Nielsen L, Beddoe T, Koh R, Richardson SK, Thakur M, Howell AR, Scott-Browne JP, Gapin L, Godfrey DI, McCluskey J, Rossjohn J
J Exp Med. 2008
PubMed ID: 18378792
Complement factor H-binding protein, a putative virulence determinant of Borrelia hermsii, is an antigenic target for protective B1b lymphocytes.
Colombo MJ, Alugupalli KR
J Immunol. 2008
PubMed ID: 18354209
A possible mechanism for non-replication of allelic association between a single nucleotide polymorphism of the human beta T-cell receptor and autoimmune diseases.
Tripputi P, Bianchi S, Fedele L
Int J Immunogenet. 2008
PubMed ID: 18279372
NK cells and gamma interferon coordinate the formation and function of hepatic granulomas in mice infected with the Francisella tularensis live vaccine strain.
Bokhari SM, Kim KJ, Pinson DM, Slusser J, Yeh HW, Parmely MJ
Infect Immun. 2008
PubMed ID: 18227174
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus.
Yager EJ, Ahmed M, Lanzer K, Randall TD, Woodland DL, Blackman MA
J Exp Med. 2008
PubMed ID: 18332179
Costimulatory blockade of CD154-CD40 in combination with T-cell lymphodepletion results in prevention of allogeneic sensitization.
Xu H, Yan J, Huang Y, Chilton PM, Ding C, Schanie CL, Wang L, Ildstad ST
Blood. 2008
PubMed ID: 17827394
Differential activation of dual promoters alters Dbeta2 germline transcription during thymocyte development.
McMillan RE, Sikes ML
J Immunol. 2008
PubMed ID: 18292546
Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement.
Ranganath S, Carpenter AC, Gleason M, Shaw AC, Bassing CH, Alt FW
J Immunol. 2008
PubMed ID: 18250443
Why T cells of thymic versus extrathymic origin are functionally different.
Blais ME, Brochu S, Giroux M, Bélanger MP, Dulude G, Sékaly RP, Perreault C
J Immunol. 2008
PubMed ID: 18250439
The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain.
Ishizuka J, Stewart-Jones GB, van der Merwe A, Bell JI, McMichael AJ, Jones EY
Immunity. 2008
PubMed ID: 18275829
Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis.
Strid J, Roberts SJ, Filler RB, Lewis JM, Kwong BY, Schpero W, Kaplan DH, Hayday AC, Girardi M
Nat Immunol. 2008
PubMed ID: 18176566
Protein kinase C theta plays a fundamental role in different types of chronic colitis.
Nagahama K, Ogawa A, Shirane K, Shimomura Y, Sugimoto K, Mizoguchi A
Gastroenterology. 2008
PubMed ID: 18155708
TNF-alpha antagonism generates a population of antigen-specific CD4+CD25+ T cells that inhibit protective immunity in murine histoplasmosis.
Deepe GS, Gibbons RS
J Immunol. 2008
PubMed ID: 18178849
Rapidly induced, T-cell independent xenoantibody production is mediated by marginal zone B cells and requires help from NK cells.
Li S, Yan Y, Lin Y, Bullens DM, Rutgeerts O, Goebels J, Segers C, Boon L, Kasran A, De Vos R, Dewolf-Peeters C, Waer M, Billiau AD
Blood. 2007
PubMed ID: 17630353
Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.
Siegers GM, Swamy M, Fernández-Malavé E, Minguet S, Rathmann S, Guardo AC, Pérez-Flores V, Regueiro JR, Alarcón B, Fisch P, Schamel WW
J Exp Med. 2007
PubMed ID: 17923503
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression.
Bunt SK, Yang L, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S
Cancer Res. 2007
PubMed ID: 17942936
Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.
Haynes NM, Allen CD, Lesley R, Ansel KM, Killeen N, Cyster JG
J Immunol. 2007
PubMed ID: 17911595
Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame.
Chang YF, Chan WK, Imam JS, Wilkinson MF
J Biol Chem. 2007
PubMed ID: 17693403
'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.
Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A
Nat Immunol. 2007
PubMed ID: 17873878
A novel mouse model for invariant NKT cell study.
Wakao H, Kawamoto H, Sakata S, Inoue K, Ogura A, Wakao R, Oda A, Fujita H
J Immunol. 2007
PubMed ID: 17785826
Cutting edge: size and diversity of CD4+CD25high Foxp3+ regulatory T cell repertoire in humans: evidence for similarities and partial overlapping with CD4+CD25- T cells.
Fazilleau N, Bachelez H, Gougeon ML, Viguier M
J Immunol. 2007
PubMed ID: 17785774
Presenilins regulate alphabeta T cell development by modulating TCR signaling.
Laky K, Fowlkes BJ
J Exp Med. 2007
PubMed ID: 17698590
Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells.
Tezuka H, Abe Y, Iwata M, Takeuchi H, Ishikawa H, Matsushita M, Shiohara T, Akira S, Ohteki T
Nature. 2007
PubMed ID: 17713535
BAFF and MyD88 signals promote a lupuslike disease independent of T cells.
Groom JR, Fletcher CA, Walters SN, Grey ST, Watt SV, Sweet MJ, Smyth MJ, Mackay CR, Mackay F
J Exp Med. 2007
PubMed ID: 17664289
A novel loop domain in superantigens extends their T cell receptor recognition site.
Günther S, Varma AK, Moza B, Kasper KJ, Wyatt AW, Zhu P, Rahman AK, Li Y, Mariuzza RA, McCormick JK, Sundberg EJ
J Mol Biol. 2007
PubMed ID: 17560605
Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers.
Grossman I, Avidan N, Singer C, Goldstaub D, Hayardeny L, Eyal E, Ben-Asher E, Paperna T, Pe'er I, Lancet D, Beckmann JS, Miller A
Pharmacogenet Genomics. 2007
PubMed ID: 17622942
Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes.
Osipovich O, Cobb RM, Oestreich KJ, Pierce S, Ferrier P, Oltz EM
Nat Immunol. 2007
PubMed ID: 17589511
Keeping the (kinase) party going: SLP-76 and ITK dance to the beat.
Qi Q, August A
Sci STKE. 2007
PubMed ID: 17652306
Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes.
Serwold T, Hochedlinger K, Inlay MA, Jaenisch R, Weissman IL
J Immunol. 2007
PubMed ID: 17617584
A chimeric TCR-beta chain confers increased susceptibility to EAE.
Petersen TR, Lata R, Spittle E, Bäckström BT
Mol Immunol. 2007
PubMed ID: 17481734
Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion.
Jia J, Kondo M, Zhuang Y
EMBO J. 2007
PubMed ID: 17410206
Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development.
Astrakhan A, Omori M, Nguyen T, Becker-Herman S, Iseki M, Aye T, Hudkins K, Dooley J, Farr A, Alpers CE, Ziegler SF, Rawlings DJ
Nat Immunol. 2007
PubMed ID: 17401368
The same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice.
Holler PD, Yamagata T, Jiang W, Feuerer M, Benoist C, Mathis D
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17438291
Characterizing tumor-promoting T cells in chemically induced cutaneous carcinogenesis.
Roberts SJ, Ng BY, Filler RB, Lewis J, Glusac EJ, Hayday AC, Tigelaar RE, Girardi M
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17412837
How a single T cell receptor recognizes both self and foreign MHC.
Colf LA, Bankovich AJ, Hanick NA, Bowerman NA, Jones LL, Kranz DM, Garcia KC
Cell. 2007
PubMed ID: 17418792
CD4+ CD25+ [corrected] regulatory T cells render naive CD4+ CD25- T cells anergic and suppressive.
Qiao M, Thornton AM, Shevach EM
Immunology. 2007
PubMed ID: 17244157
Mouse model of oral infection with virulent type A Francisella tularensis.
KuoLee R, Zhao X, Austin J, Harris G, Conlan JW, Chen W
Infect Immun. 2007
PubMed ID: 17242058
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis.
Veiga-Fernandes H, Coles MC, Foster KE, Patel A, Williams A, Natarajan D, Barlow A, Pachnis V, Kioussis D
Nature. 2007
PubMed ID: 17322904
MyD88- and Bruton's tyrosine kinase-mediated signals are essential for T cell-independent pathogen-specific IgM responses.
Alugupalli KR, Akira S, Lien E, Leong JM
J Immunol. 2007
PubMed ID: 17339472
Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications.
Wu C, Ranganath S, Gleason M, Woodman BB, Borjeson TM, Alt FW, Bassing CH
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17360467
Disruption of extracellular interactions impairs T cell receptor-CD3 complex stability and signaling.
Kuhns MS, Davis MM
Immunity. 2007
PubMed ID: 17368054
Foxp3-dependent programme of regulatory T-cell differentiation.
Gavin MA, Rasmussen JP, Fontenot JD, Vasta V, Manganiello VC, Beavo JA, Rudensky AY
Nature. 2007
PubMed ID: 17220874
Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.
Melichar HJ, Narayan K, Der SD, Hiraoka Y, Gardiol N, Jeannet G, Held W, Chambers CA, Kang J
Science. 2007
PubMed ID: 17218525
The germinal center response is impaired in the absence of T cell-expressed CXCR5.
Arnold CN, Campbell DJ, Lipp M, Butcher EC
Eur J Immunol. 2007
PubMed ID: 17171760
Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models.
Kühl AA, Pawlowski NN, Grollich K, Loddenkemper C, Zeitz M, Hoffmann JC
J Leukoc Biol. 2007
PubMed ID: 17041003
Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex.
Heemskerk MH, Hagedoorn RS, van der Hoorn MA, van der Veken LT, Hoogeboom M, Kester MG, Willemze R, Falkenburg JH
Blood. 2007
PubMed ID: 16968899
Early events in the thymus affect the balance of effector and regulatory T cells.
Pennington DJ, Silva-Santos B, Silberzahn T, Escórcio-Correia M, Woodward MJ, Roberts SJ, Smith AL, Dyson PJ, Hayday AC
Nature. 2006
PubMed ID: 17190001
A natural structural variant of the mouse TCR beta-chain displays intrinsic receptor function and antigen specificity.
Aublin A, Ciofani M, Willkomm N, Hamrouni A, Szymczak-Workman AL, Takahashi T, Sandjeu Y, Guillaume P, Vignali DA, Michielin O, Zúñiga-Pflücker JC, Maryanski JL
J Immunol. 2006
PubMed ID: 17142757
A membrane-proximal tetracysteine motif contributes to assembly of CD3deltaepsilon and CD3gammaepsilon dimers with the T cell receptor.
Xu C, Call ME, Wucherpfennig KW
J Biol Chem. 2006
PubMed ID: 17023417
GATA-3 regulates the development and function of invariant NKT cells.
Kim PJ, Pai SY, Brigl M, Besra GS, Gumperz J, Ho IC
J Immunol. 2006
PubMed ID: 17082577
TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation.
Ferrero I, Mancini SJ, Grosjean F, Wilson A, Otten L, MacDonald HR
J Immunol. 2006
PubMed ID: 17056529
c-Myc mediates pre-TCR-induced proliferation but not developmental progression.
Dose M, Khan I, Guo Z, Kovalovsky D, Krueger A, von Boehmer H, Khazaie K, Gounari F
Blood. 2006
PubMed ID: 16788099
gammadelta T cells condition dendritic cells in vivo for priming pulmonary CD8 T cell responses against Mycobacterium tuberculosis.
Caccamo N, Sireci G, Meraviglia S, Dieli F, Ivanyi J, Salerno A
Eur J Immunol. 2006
PubMed ID: 16981183
T and B lymphocytes exert distinct effects on the homeostasis of NK cells.
Jeannet G, Coudert JD, Held W
Eur J Immunol. 2006
PubMed ID: 16955521
Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease.
Enzler T, Bonizzi G, Silverman GJ, Otero DC, Widhopf GF, Anzelon-Mills A, Rickert RC, Karin M
Immunity. 2006
PubMed ID: 16973390
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor.
Marie JC, Liggitt D, Rudensky AY
Immunity. 2006
PubMed ID: 16973387
Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection.
Louten J, van Rooijen N, Biron CA
J Immunol. 2006
PubMed ID: 16920967
Humoral immune response to flagellin requires T cells and activation of innate immunity.
Sanders CJ, Yu Y, Moore DA, Williams IR, Gewirtz AT
J Immunol. 2006
PubMed ID: 16920916
Induction of IgE and allergic-type responses in fur mite-infested mice.
Pochanke V, Hatak S, Hengartner H, Zinkernagel RM, McCoy KD
Eur J Immunol. 2006
PubMed ID: 16909433
Antibody-mediated disease remission in the mouse model of lyme borreliosis.
Barthold SW, Hodzic E, Tunev S, Feng S
Infect Immun. 2006
PubMed ID: 16861670
Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.
Taylor KN, Shinde Patil VR, Colson YL
J Immunol. 2006
PubMed ID: 16849450
Molecular analysis of T-cell receptor beta genes in cutaneous T-cell lymphoma reveals Jbeta1 bias.
Morgan SM, Hodges E, Mitchell TJ, Harris S, Whittaker SJ, Smith JL
J Invest Dermatol. 2006
PubMed ID: 16741518
CD4+ T cells and CXC chemokines modulate the pathogenesis of Staphylococcus aureus wound infections.
McLoughlin RM, Solinga RM, Rich J, Zaleski KJ, Cocchiaro JL, Risley A, Tzianabos AO, Lee JC
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16801559
A role for IFNgamma in differential superantigen stimulation of conventional versus plasmacytoid DCs.
Muralimohan G, Vella AT
Cell Immunol. 2006
PubMed ID: 17045255
Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRbeta locus rearrangements and putative new T-cell oncogenes.
Cauwelier B, Dastugue N, Cools J, Poppe B, Herens C, De Paepe A, Hagemeijer A, Speleman F
Leukemia. 2006
PubMed ID: 16673021
Peyer's patches are required for the induction of rapid Th1 responses in the gut and mesenteric lymph nodes during an enteric infection.
Kwa SF, Beverley P, Smith AL
J Immunol. 2006
PubMed ID: 16751400
Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation.
Shaw MH, Freeman GJ, Scott MF, Fox BA, Bzik DJ, Belkaid Y, Yap GS
J Immunol. 2006
PubMed ID: 16751369
The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells.
Aifantis I, Bassing CH, Garbe AI, Sawai K, Alt FW, von Boehmer H
J Exp Med. 2006
PubMed ID: 16754716
Involvement of gonadal steroids and gamma interferon in sex differences in response to blood-stage malaria infection.
Cernetich A, Garver LS, Jedlicka AE, Klein PW, Kumar N, Scott AL, Klein SL
Infect Immun. 2006
PubMed ID: 16714546
Identical TCR beta-chain rearrangements in streptococcal angina and skin lesions of patients with psoriasis vulgaris.
Diluvio L, Vollmer S, Besgen P, Ellwart JW, Chimenti S, Prinz JC
J Immunol. 2006
PubMed ID: 16709873
The TCR C beta FG loop regulates alpha beta T cell development.
Touma M, Chang HC, Sasada T, Handley M, Clayton LK, Reinherz EL
J Immunol. 2006
PubMed ID: 16709841
Evidence for a functional second thymus in mice.
Terszowski G, Müller SM, Bleul CC, Blum C, Schirmbeck R, Reimann J, Pasquier LD, Amagai T, Boehm T, Rodewald HR
Science. 2006
PubMed ID: 16513945
Expression of rearranged TCRgamma genes in natural killer cells suggests a minor thymus-dependent pathway of lineage commitment.
Veinotte LL, Greenwood CP, Mohammadi N, Parachoniak CA, Takei F
Blood. 2006
PubMed ID: 16317098
Genetic dissection of vasculitis, myeloperoxidase-specific antineutrophil cytoplasmic autoantibody production, and related traits in spontaneous crescentic glomerulonephritis-forming/Kinjoh mice.
Hamano Y, Tsukamoto K, Abe M, Sun GD, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Okawara A, Tachikawa H, Nishimura H, Tokunaka K, Hirose S, Suzuki K
J Immunol. 2006
PubMed ID: 16517735
Natural IgE production in the absence of MHC Class II cognate help.
McCoy KD, Harris NL, Diener P, Hatak S, Odermatt B, Hangartner L, Senn BM, Marsland BJ, Geuking MB, Hengartner H, Macpherson AJ, Zinkernagel RM
Immunity. 2006
PubMed ID: 16546101
T-independent type II immune responses generate memory B cells.
Obukhanych TV, Nussenzweig MC
J Exp Med. 2006
PubMed ID: 16476769
Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.
Le Bon A, Thompson C, Kamphuis E, Durand V, Rossmann C, Kalinke U, Tough DF
J Immunol. 2006
PubMed ID: 16455962
Human alpha beta and gamma delta thymocyte development: TCR gene rearrangements, intracellular TCR beta expression, and gamma delta developmental potential--differences between men and mice.
Joachims ML, Chain JL, Hooker SW, Knott-Craig CJ, Thompson LF
J Immunol. 2006
PubMed ID: 16424183
Extensive T cell receptor cross-reactivity on structurally diverse haptenated peptides presented by HLA-A2.
Gagnon SJ, Turner RV, Shiue MG, Damirjian M, Biddison WE
Mol Immunol. 2006
PubMed ID: 16310048
Stoichiometry of the murine gammadelta T cell receptor.
Hayes SM, Love PE
J Exp Med. 2006
PubMed ID: 16418397
Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus.
Taghon T, Yui MA, Pant R, Diamond RA, Rothenberg EV
Immunity. 2006
PubMed ID: 16413923
Role of the T-cell receptor in kidney ischemia-reperfusion injury.
Savransky V, Molls RR, Burne-Taney M, Chien CC, Racusen L, Rabb H
Kidney Int. 2006
PubMed ID: 16408111
T cell-induced inflammation of the small and large intestine in immunodeficient mice.
Ostanin DV, Pavlick KP, Bharwani S, D'Souza D, Furr KL, Brown CM, Grisham MB
Am J Physiol Gastrointest Liver Physiol. 2006
PubMed ID: 16099868
A requirement for the Vgamma1+ subset of peripheral gammadelta T cells in the control of the systemic growth of Toxoplasma gondii and infection-induced pathology.
Egan CE, Dalton JE, Andrew EM, Smith JE, Gubbels MJ, Striepen B, Carding SR
J Immunol. 2005
PubMed ID: 16339558
Mast cells are required for optimal autoreactive T cell responses in a murine model of multiple sclerosis.
Gregory GD, Robbie-Ryan M, Secor VH, Sabatino JJ, Brown MA
Eur J Immunol. 2005
PubMed ID: 16285014
The positional effect of Ebeta on Vbeta genes of TCRbeta chain in the ordered rearrangement and allelic exclusion.
Suzuki D, Wang L, Senoo M, Habu S
Int Immunol. 2005
PubMed ID: 16219638
Immune complex-dependent remodeling of the airway vasculature in response to a chronic bacterial infection.
Aurora AB, Baluk P, Zhang D, Sidhu SS, Dolganov GM, Basbaum C, McDonald DM, Killeen N
J Immunol. 2005
PubMed ID: 16272283
Cell surface recycling of internalized antigen permits dendritic cell priming of B cells.
Bergtold A, Desai DD, Gavhane A, Clynes R
Immunity. 2005
PubMed ID: 16286018
CD4 T cell-independent antibody response promotes resolution of primary influenza infection and helps to prevent reinfection.
Lee BO, Rangel-Moreno J, Moyron-Quiroz JE, Hartson L, Makris M, Sprague F, Lund FE, Randall TD
J Immunol. 2005
PubMed ID: 16237075
Allele-specific regulation of TCR beta variable gene segment chromatin structure.
Jackson AM, Krangel MS
J Immunol. 2005
PubMed ID: 16210623
{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.
French JD, Roark CL, Born WK, O'brien RL
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16203967
Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes.
Cariappa A, Mazo IB, Chase C, Shi HN, Liu H, Li Q, Rose H, Leung H, Cherayil BJ, Russell P, von Andrian U, Pillai S
Immunity. 2005
PubMed ID: 16226505
Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint.
Williams JA, Hathcock KS, Klug D, Harada Y, Choudhury B, Allison JP, Abe R, Hodes RJ
J Immunol. 2005
PubMed ID: 16177059
Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin.
Yoo J, Omori M, Gyarmati D, Zhou B, Aye T, Brewer A, Comeau MR, Campbell DJ, Ziegler SF
J Exp Med. 2005
PubMed ID: 16103410
Transient loss of MHC class I tetramer binding after CD8+ T cell activation reflects altered T cell effector function.
Drake DR, Ream RM, Lawrence CW, Braciale TJ
J Immunol. 2005
PubMed ID: 16034088
Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus.
Dandekar AA, O'Malley K, Perlman S
J Virol. 2005
PubMed ID: 16014902
Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection.
Warfield KL, Olinger G, Deal EM, Swenson DL, Bailey M, Negley DL, Hart MK, Bavari S
J Immunol. 2005
PubMed ID: 16002721
Regulation of follicular dendritic cell networks by activated T cells: the role of CD137 signaling.
Sun Y, Blink SE, Chen JH, Fu YX
J Immunol. 2005
PubMed ID: 16002686
The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cells.
Prinz I, Gregoire C, Mollenkopf H, Aguado E, Wang Y, Malissen M, Kaufmann SH, Malissen B
J Immunol. 2005
PubMed ID: 16002666
Critical role of host gammadelta T cells in experimental acute graft-versus-host disease.
Maeda Y, Reddy P, Lowler KP, Liu C, Bishop DK, Ferrara JL
Blood. 2005
PubMed ID: 15797996
Restricted MHC-peptide repertoire predisposes to autoimmunity.
Logunova NN, Viret C, Pobezinsky LA, Miller SA, Kazansky DB, Sundberg JP, Chervonsky AV
J Exp Med. 2005
PubMed ID: 15998789
Generation of cloned mice by direct nuclear transfer from natural killer T cells.
Inoue K, Wakao H, Ogonuki N, Miki H, Seino K, Nambu-Wakao R, Noda S, Miyoshi H, Koseki H, Taniguchi M, Ogura A
Curr Biol. 2005
PubMed ID: 15964276
Rearrangement of T-cell receptor beta and gamma genes in thymoma.
Nakajima J, Matsumoto J, Takeuchi E, Fukami T, Takamoto S
Asian Cardiovasc Thorac Ann. 2005
PubMed ID: 15905344
Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection.
Kursar M, Höpken UE, Koch M, Köhler A, Lipp M, Kaufmann SH, Mittrücker HW
J Exp Med. 2005
PubMed ID: 15851484
TCR signal strength influences alphabeta/gammadelta lineage fate.
Hayes SM, Li L, Love PE
Immunity. 2005
PubMed ID: 15894276
Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis.
Vielhauer V, Stavrakis G, Mayadas TN
J Clin Invest. 2005
PubMed ID: 15841213
Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.
Kabashima K, Banks TA, Ansel KM, Lu TT, Ware CF, Cyster JG
Immunity. 2005
PubMed ID: 15845449
A deficiency in gamma interferon or interleukin-10 modulates T-Cell-dependent responses to heat shock protein 60 from Histoplasma capsulatum.
Scheckelhoff M, Deepe GS
Infect Immun. 2005
PubMed ID: 15784555
Mast cells limit systemic bacterial dissemination but not colitis in response to Citrobacter rodentium.
Wei OL, Hilliard A, Kalman D, Sherman M
Infect Immun. 2005
PubMed ID: 15784538
Accumulation of intestinal intraepithelial lymphocytes in association with lack of polymeric immunoglobulin receptor.
Yamazaki K, Shimada S, Kato-Nagaoka N, Soga H, Itoh T, Nanno M
Eur J Immunol. 2005
PubMed ID: 15770700
Helminth regulation of host IL-4Ralpha/Stat6 signaling: mechanism underlying NOS-2 inhibition by Trichinella spiralis.
Bian K, Zhong M, Harari Y, Lai M, Weisbrodt N, Murad F
Proc Natl Acad Sci U S A. 2005
PubMed ID: 15741272
Regulatory T cell lineage specification by the forkhead transcription factor foxp3.
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY
Immunity. 2005
PubMed ID: 15780990
Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes.
Sato T, Ohno S, Hayashi T, Sato C, Kohu K, Satake M, Habu S
Immunity. 2005
PubMed ID: 15780989
Analysis of the insertion/deletion related polymorphism within T cell antigen receptor beta variable genes in primary Sjögren's syndrome.
Lawson CA, Donaldson IJ, Bowman SJ, Shefta J, Morgan AW, Gough A, Isaacs JD, Griffiths B, Emery P, Pease CT, Boylston AW
Ann Rheum Dis. 2005
PubMed ID: 15708895
Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function.
Koneru M, Schaer D, Monu N, Ayala A, Frey AB
J Immunol. 2005
PubMed ID: 15699109
IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis.
Wensky AK, Furtado GC, Marcondes MC, Chen S, Manfra D, Lira SA, Zagzag D, Lafaille JJ
J Immunol. 2005
PubMed ID: 15661899
Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility.
Jackson A, Kondilis HD, Khor B, Sleckman BP, Krangel MS
Nat Immunol. 2005
PubMed ID: 15640803
Nonsense-associated alternative splicing of T-cell receptor beta genes: no evidence for frame dependence.
Mohn F, Bühler M, Mühlemann O
RNA. 2005
PubMed ID: 15613535
Differences in pairing and cluster formation of T cell receptor alpha- and beta-chains in T cell clones and fusion hybridomas.
Hellwig S, Schamel WW, Pflugfelder U, Gerlich B, Weltzien HU
Immunobiology. 2005
PubMed ID: 16323705
Pathogenesis of enterotropic mouse hepatitis virus in immunocompetent and immunodeficient mice.
Compton SR, Ball-Goodrich LJ, Johnson LK, Johnson EA, Paturzo FX, Macy JD
Comp Med. 2004
PubMed ID: 15679267
Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice.
Elhage R, Gourdy P, Brouchet L, Jawien J, Fouque MJ, Fiévet C, Huc X, Barreira Y, Couloumiers JC, Arnal JF, Bayard F
Am J Pathol. 2004
PubMed ID: 15579444
The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus.
Eyquem S, Chemin K, Fasseu M, Bories JC
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15496469
Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties.
Malherbe L, Hausl C, Teyton L, McHeyzer-Williams MG
Immunity. 2004
PubMed ID: 15539153
Matching T-cell receptors identified in renal biopsies and urine at the time of acute rejection in pediatric renal transplant patients.
Hu M, Zhang GY, Walters G, Sartor M, Watson D, Knight JF, Alexander SI
Am J Transplant. 2004
PubMed ID: 15476487
Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.
Palacios EH, Weiss A
Oncogene. 2004
PubMed ID: 15489916
CD4+CD45RBHi interleukin-4 defective T cells elicit antral gastritis and duodenitis.
Dohi T, Fujihashi K, Koga T, Etani Y, Yoshino N, Kawamura YI, McGhee JR
Am J Pathol. 2004
PubMed ID: 15466391
A profound alteration of blood TCRB repertoire allows prediction of cerebral malaria.
Collette A, Bagot S, Ferrandiz ME, Cazenave PA, Six A, Pied S
J Immunol. 2004
PubMed ID: 15383590
CD8 T cell responses to lymphocytic choriomeningitis virus in early growth response gene 1-deficient mice.
Singh A, Svaren J, Grayson J, Suresh M
J Immunol. 2004
PubMed ID: 15356133
B1b lymphocytes confer T cell-independent long-lasting immunity.
Alugupalli KR, Leong JM, Woodland RT, Muramatsu M, Honjo T, Gerstein RM
Immunity. 2004
PubMed ID: 15357949
STAT5 is required for thymopoiesis in a development stage-specific manner.
Kang J, DiBenedetto B, Narayan K, Zhao H, Der SD, Chambers CA
J Immunol. 2004
PubMed ID: 15294943
IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis.
Binder CJ, Hartvigsen K, Chang MK, Miller M, Broide D, Palinski W, Curtiss LK, Corr M, Witztum JL
J Clin Invest. 2004
PubMed ID: 15286809
The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion.
Ryu CJ, Haines BB, Lee HR, Kang YH, Draganov DD, Lee M, Whitehurst CE, Hong HJ, Chen J
Mol Cell Biol. 2004
PubMed ID: 15282302
Defined alphabeta T cell receptors with distinct ligand specificities do not require those ligands to signal double negative thymocyte differentiation.
Erman B, Guinter TI, Singer A
J Exp Med. 2004
PubMed ID: 15210747
CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis.
Peters W, Cyster JG, Mack M, Schlöndorff D, Wolf AJ, Ernst JD, Charo IF
J Immunol. 2004
PubMed ID: 15187146
Contribution of alphabeta and gammadelta T cells to the generation of primary immunoglobulin G-driven autoimmune response in immunoglobulin- mu-deficient/lpr mice.
Seagal J, Melamed D
Immunology. 2004
PubMed ID: 15147570
Mutations of the T-cell receptor constant region after in utero stem cell transplantation.
Pirovano S, Notarangelo LD, Valotti M, Ugazio AG, Albertini A, Imberti L
Immunogenetics. 2004
PubMed ID: 15138733
The role of IL-5 for mature B-1 cells in homeostatic proliferation, cell survival, and Ig production.
Moon BG, Takaki S, Miyake K, Takatsu K
J Immunol. 2004
PubMed ID: 15128785
Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation.
Ciofani M, Schmitt TM, Ciofani A, Michie AM, Cuburu N, Aublin A, Maryanski JL, Zúñiga-Pflücker JC
J Immunol. 2004
PubMed ID: 15100261
Susceptibility of T cell receptor-alpha chain knock-out mice to ultraviolet B light and fluorouracil: a novel model for drug-induced cutaneous lupus erythematosus.
Yoshimasu T, Nishide T, Seo N, Hiroi A, Ohtani T, Uede K, Furukawa F
Clin Exp Immunol. 2004
PubMed ID: 15086387
Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope.
Kedzierska K, Turner SJ, Doherty PC
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15037737
Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro.
Schmitt TM, de Pooter RF, Gronski MA, Cho SK, Ohashi PS, Zúñiga-Pflücker JC
Nat Immunol. 2004
PubMed ID: 15034575
Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen.
Bry L, Brenner MB
J Immunol. 2004
PubMed ID: 14688352
A role for TCR affinity in regulating naive T cell homeostasis.
Kieper WC, Burghardt JT, Surh CD
J Immunol. 2004
PubMed ID: 14688307
Analysis of two T-cell receptor BV gene segment polymorphisms in caucasoid Brazilian patients with rheumatoid arthritis.
Dresch C, Xavier R, Brenol JC, Nardi NB, Chies JA
Immunol Lett. 2003
PubMed ID: 14687707
Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin.
Ashcroft AJ, Cruickshank SM, Croucher PI, Perry MJ, Rollinson S, Lippitt JM, Child JA, Dunstan C, Felsburg PJ, Morgan GJ, Carding SR
Immunity. 2003
PubMed ID: 14670302
Role of gamma delta T cells in the inflammatory response of experimental colitis mice.
Tsuchiya T, Fukuda S, Hamada H, Nakamura A, Kohama Y, Ishikawa H, Tsujikawa K, Yamamoto H
J Immunol. 2003
PubMed ID: 14607957
Protective and memory immunity to Histoplasma capsulatum in the absence of IL-10.
Deepe GS, Gibbons RS
J Immunol. 2003
PubMed ID: 14607938
The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombination.
Ryu CJ, Haines BB, Draganov DD, Kang YH, Whitehurst CE, Schmidt T, Hong HJ, Chen J
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14593206
Expression of T cell receptor beta locus in central nervous system neurons.
Syken J, Shatz CJ
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14569018
The inter-relatedness and interdependence of mouse T cell receptor gammadelta+ and alphabeta+ cells.
Pennington DJ, Silva-Santos B, Shires J, Theodoridis E, Pollitt C, Wise EL, Tigelaar RE, Owen MJ, Hayday AC
Nat Immunol. 2003
PubMed ID: 14502287
Constitutive expression of a costimulatory ligand on antigen-presenting cells in the nervous system drives demyelinating disease.
Zehntner SP, Brisebois M, Tran E, Owens T, Fournier S
FASEB J. 2003
PubMed ID: 12923072
V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice.
Hahn YS, Taube C, Jin N, Takeda K, Park JW, Wands JM, Aydintug MK, Roark CL, Lahn M, O'Brien RL, Gelfand EW, Born WK
J Immunol. 2003
PubMed ID: 12960345
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancer.
Girardi M, Glusac E, Filler RB, Roberts SJ, Propperova I, Lewis J, Tigelaar RE, Hayday AC
J Exp Med. 2003
PubMed ID: 12953094
IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection.
Wang T, Scully E, Yin Z, Kim JH, Wang S, Yan J, Mamula M, Anderson JF, Craft J, Fikrig E
J Immunol. 2003
PubMed ID: 12928402
T cell receptor transfection shows non-HLA-restricted recognition of nickel by CD8+ human T cells to be mediated by alphabeta T cell receptors.
Moulon C, Choleva Y, Thierse HJ, Wild D, Weltzien HU
J Invest Dermatol. 2003
PubMed ID: 12925207
Increased plasma cell frequency and accumulation of abnormal syndecan-1plus T-cells in Igmu-deficient/lpr mice.
Seagal J, Leider N, Wildbaum G, Karin N, Melamed D
Int Immunol. 2003
PubMed ID: 12917256
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development.
Vosshenrich CA, Cumano A, Müller W, Di Santo JP, Vieira P
Nat Immunol. 2003
PubMed ID: 12872121
Increase of TCR V beta accessibility within E beta regulatory region influences its recombination frequency but not allelic exclusion.
Senoo M, Wang L, Suzuki D, Takeda N, Shinkai Y, Habu S
J Immunol. 2003
PubMed ID: 12847251
Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balan
Emoto M, Emoto Y, Brinkmann V, Miyamoto M, Yoshizawa I, Stäber M, van Rooijen N, Hamann A, Kaufmann SH
J Immunol. 2003
PubMed ID: 12847222
T-cell receptor polymorphism in primary biliary cirrhosis.
Selmi C, Invernizzi P, Tripputi P, Battezzati PM, Bignotto M, Zuin M, Crosignani A, Podda M
Ann Ital Med Int. 2003
PubMed ID: 14621425
Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.
Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, Mishima Y, Hitomi J, Yamamoto T, Utsuyama M, Niwa O, Aizawa S, Kominami R
Nat Immunol. 2003
PubMed ID: 12717433
Assessing the role of the T cell receptor beta gene enhancer in regulating coding joint formation during V(D)J recombination.
Mathieu N, Spicuglia S, Gorbatch S, Cabaud O, Fernex C, Verthuy C, Hempel WM, Hueber AO, Ferrier P
J Biol Chem. 2003
PubMed ID: 12639959
The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes.
Alugupalli KR, Gerstein RM, Chen J, Szomolanyi-Tsuda E, Woodland RT, Leong JM
J Immunol. 2003
PubMed ID: 12646649
T helper type-2 cells induce ileal villus atrophy, goblet cell metaplasia, and wasting disease in T cell-deficient mice.
Dohi T, Fujihashi K, Koga T, Shirai Y, Kawamura YI, Ejima C, Kato R, Saitoh K, McGhee JR
Gastroenterology. 2003
PubMed ID: 12612906
CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism.
Chung DR, Kasper DL, Panzo RJ, Chitnis T, Grusby MJ, Sayegh MH, Tzianabos AO, Chtinis T
J Immunol. 2003
PubMed ID: 12574364
Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice.
Guy-Grand D, Azogui O, Celli S, Darche S, Nussenzweig MC, Kourilsky P, Vassalli P
J Exp Med. 2003
PubMed ID: 12566417
A serine/threonine phosphorylation site in the ectodomain of a T cell receptor beta chain is required for activation by superantigen.
Lukashev DE, Caldwell CC, Chen P, Apasov SG, Margulies DH, Sitkovsky MV
J Recept Signal Transduct Res. 2003
PubMed ID: 12680588
Helicobacter pylori infection: CagA-specific antibodies are associated with clinical outcome, but not with HLA-class II polymorphisms of the host.
Kunstmann E, Hardt C, Crabtree JE, Suerbaum S, Epplen JT
Int J Med Microbiol. 2003
PubMed ID: 12635936
Combination antiretroviral therapy results in a rapid increase in T cell receptor variable region beta repertoire diversity within CD45RA CD8 T cells in human immunodeficiency virus-infected children.
Kou ZC, Puhr JS, Wu SS, Goodenow MM, Sleasman JW
J Infect Dis. 2003
PubMed ID: 12552422
Clonally expanded CD4+CD28null T cells in rheumatoid arthritis use distinct combinations of T cell receptor BV and BJ elements.
Wagner U, Pierer M, Kaltenhäuser S, Wilke B, Seidel W, Arnold S, Häntzschel H
Eur J Immunol. 2003
PubMed ID: 12594835
Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence.
Wu C, Bassing CH, Jung D, Woodman BB, Foy D, Alt FW
Immunity. 2003
PubMed ID: 12530977
gammadelta T cells contribute to the systemic immunoglobulin E response and local B-cell reactivity in allergic eosinophilic airway inflammation.
Svensson L, Lilliehöök B, Larsson R, Bucht A
Immunology. 2003
PubMed ID: 12519308
A novel estrogen receptor alpha-associated protein, template-activating factor Ibeta, inhibits acetylation and transactivation.
Loven MA, Muster N, Yates JR, Nardulli AM
Mol Endocrinol. 2003
PubMed ID: 12511607
Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation.
Mizoguchi A, Mizoguchi E, de Jong YP, Takedatsu H, Preffer FI, Terhorst C, Bhan AK
Int Immunol. 2003
PubMed ID: 12502730
Substantial N diversity is generated in T cell receptor alpha genes at birth despite low levels of terminal deoxynucleotidyl transferase expression in mouse thymus.
Cherrier M, Cardona A, Rosinski-Chupin I, Rougeon F, Doyen N
Eur J Immunol. 2002
PubMed ID: 12516554
Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes.
Spicuglia S, Kumar S, Yeh JH, Vachez E, Chasson L, Gorbatch S, Cautres J, Ferrier P
Mol Cell. 2002
PubMed ID: 12504021
Antigen-specific dose-dependent system for the study of an inheritable and reversible phenotype in mouse CD4+ T cells.
Firpo EJ, Kong RK, Zhou Q, Rudensky AY, Roberts JM, Franza BR
Immunology. 2002
PubMed ID: 12460193
Differential regulation between gene expression and histone H3 acetylation in the variable regions of the TCRbeta locus.
Wang L, Senoo M, Habu S
Biochem Biophys Res Commun. 2002
PubMed ID: 12413958
Virulent but not avirulent Mycobacterium tuberculosis can evade the growth inhibitory action of a T helper 1-dependent, nitric oxide Synthase 2-independent defense in mice.
Jung YJ, LaCourse R, Ryan L, North RJ
J Exp Med. 2002
PubMed ID: 12370260
Conserved TCR beta chain usage in reactive arthritis; evidence for selection by a putative HLA-B27-associated autoantigen.
May E, Dulphy N, Frauendorf E, Duchmann R, Bowness P, Lopez de Castro JA, Toubert A, Märker-Hermann E
Tissue Antigens. 2002
PubMed ID: 12472659
Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice.
Engel I, Murre C
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12172006
MUC1-specific anti-tumor responses: molecular requirements for CD4-mediated responses.
VanLith ML, Kohlgraf KG, Sivinski CL, Tempero RM, Hollingsworth MA
Int Immunol. 2002
PubMed ID: 12147624
The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivo.
Park MK, Amichay D, Love P, Wick E, Liao F, Grinberg A, Rabin RL, Zhang HH, Gebeyehu S, Wright TM, Iwasaki A, Weng Y, DeMartino JA, Elkins KL, Farber JM
J Immunol. 2002
PubMed ID: 12133969
Alternatively spliced TCR mRNA induced by disruption of reading frame.
Wang J, Hamilton JI, Carter MS, Li S, Wilkinson MF
Science. 2002
PubMed ID: 12098701
Analysis of the T-cell receptor beta-chain variable-region (Vbeta) repertoire in chronic human Chagas' disease.
Fernández-Mestre MT, Jaraquemada D, Bruno RE, Caro J, Layrisse Z
Tissue Antigens. 2002
PubMed ID: 12366778
Conserved CDR 3 region of T cell receptor BV gene in lymphocytes from bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis.
Shimizudani N, Murata H, Keino H, Kojo S, Nakamura H, Morishima Y, Sakamoto T, Ohtsuka M, Sekisawa K, Sumida M, Sumida T, Matsuoka T
Clin Exp Immunol. 2002
PubMed ID: 12100034
Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.
Gil D, Schamel WW, Montoya M, Sánchez-Madrid F, Alarcón B
Cell. 2002
PubMed ID: 12110186
Involvement of the TCR Cbeta FG loop in thymic selection and T cell function.
Sasada T, Touma M, Chang HC, Clayton LK, Wang JH, Reinherz EL
J Exp Med. 2002
PubMed ID: 12045240
Regional variation of the alphabeta T cell repertoire in the colon of healthy individuals and patients with Crohn's disease.
May E, Lambert C, Holtmeier W, Hennemann A, Zeitz M, Duchmann R
Hum Immunol. 2002
PubMed ID: 12039522
Early response to rotavirus infection involves massive B cell activation.
Blutt SE, Warfield KL, Lewis DE, Conner ME
J Immunol. 2002
PubMed ID: 12023371
B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion.
Yu P, Wang Y, Chin RK, Martinez-Pomares L, Gordon S, Kosco-Vibois MH, Cyster J, Fu YX
J Immunol. 2002
PubMed ID: 11994465
A role for CD147 in thymic development.
Renno T, Wilson A, Dunkel C, Coste I, Maisnier-Patin K, Benoit de Coignac A, Aubry JP, Lees RK, Bonnefoy JY, MacDonald HR, Gauchat JF
J Immunol. 2002
PubMed ID: 11994445
Negative selection of thymocytes expressing the D10 TCR.
Sant'Angelo DB, Janeway CA
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12011450
CD4(+) T cell-dependent airway mucus production occurs in response to IL-5 expression in lung.
Justice JP, Crosby J, Borchers MT, Tomkinson A, Lee JJ, Lee NA
Am J Physiol Lung Cell Mol Physiol. 2002
PubMed ID: 11943672
Early phase bronchoconstriction in the mouse requires allergen-specific IgG.
Crosby JR, Cieslewicz G, Borchers M, Hines E, Carrigan P, Lee JJ, Lee NA
J Immunol. 2002
PubMed ID: 11937563
Thymopoiesis requires Pax9 function in thymic epithelial cells.
Hetzer-Egger C, Schorpp M, Haas-Assenbaum A, Balling R, Peters H, Boehm T
Eur J Immunol. 2002
PubMed ID: 11932925
Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation.
Girardi M, Lewis J, Glusac E, Filler RB, Geng L, Hayday AC, Tigelaar RE
J Exp Med. 2002
PubMed ID: 11927630
Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy.
Jones TB, Basso DM, Sodhi A, Pan JZ, Hart RP, MacCallum RC, Lee S, Whitacre CC, Popovich PG
J Neurosci. 2002
PubMed ID: 11923434
Human T cell receptor-mediated recognition of HLA-E.
García P, Llano M, de Heredia AB, Willberg CB, Caparrós E, Aparicio P, Braud VM, López-Botet M
Eur J Immunol. 2002
PubMed ID: 11920559
IL-4 and T cells are required for the generation of IgG1 isotype antibodies against cardiolipin.
Fischer K, Collins H, Taniguchi M, Kaufmann SH, Schaible UE
J Immunol. 2002
PubMed ID: 11884434
Homeostatic regulation of intestinal villous epithelia by B lymphocytes.
Nishiyama Y, Hamada H, Nonaka S, Yamamoto H, Nanno M, Katayama Y, Takahashi H, Ishikawa H
J Immunol. 2002
PubMed ID: 11884426
Discordance between T-cell receptor expression and effector function in mice infected with Histoplasma capsulatum.
Deepe GS, Gibbons RS, Ward SR
Infect Immun. 2002
PubMed ID: 11854260
T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells.
Yin Z, Chen C, Szabo SJ, Glimcher LH, Ray A, Craft J
J Immunol. 2002
PubMed ID: 11823483
Malaria is not responsible for the selection of TCR beta-subunit variable gene haplotypes in The Gambia.
Donaldson IJ, Shefta J, Hill AV, Boylston AW
Immunogenetics. 2002
PubMed ID: 11862389
Unique TCR beta-subunit variable gene haplotypes in Africans.
Donaldson IJ, Shefta J, Lawson CA, Bushnell JR, Morgan AW, Isaacs JD, Carpenter D, Shaw MA, Rooth I, Quinnell RJ, Zumla AM, Ollier WR, Chintu CZ, Muyinda GP, Hill AS, Boylston AW
Immunogenetics. 2002
PubMed ID: 11862388
TCRBV3S1 and TCRBV18 gene segment polymorphisms in Brazilian Caucasoid and Black populations.
Dresch C, Nardi NB, Chies JA
Eur J Immunogenet. 2002
PubMed ID: 11841483
Adapters in lymphocyte signaling.
Leo A, Wienands J, Baier G, Horejsi V, Schraven B
J Clin Invest. 2002
PubMed ID: 11827988
The role of T cell help in the production of antibodies specific for Gal alpha 1-3Gal.
Cretin N, Bracy J, Hanson K, Iacomini J
J Immunol. 2002
PubMed ID: 11801692
Chromosomal localization of three vacuolar-H+ -ATPase 16 kDa subunit (ATP6V0C) genes in the murine genome.
Simckes AM, Swanson SK, White RA
Cytogenet Genome Res. 2002
PubMed ID: 12438748
Animal models of human disease: experimental autoimmune gastritis--a model for autoimmune gastritis and pernicious anemia.
Alderuccio F, Sentry JW, Marshall AC, Biondo M, Toh BH
Clin Immunol. 2002
PubMed ID: 11781067
TCRbeta transmembrane tyrosines are required for pre-TCR function.
Spain LM, Liu P
J Immunol. 2002
PubMed ID: 11751955
Ectopic expression of IL-5 identifies an additional CD4(+) T cell mechanism of airway eosinophil recruitment.
Crosby JR, Shen HH, Borchers MT, Justice JP, Ansay T, Lee JJ, Lee NA
Am J Physiol Lung Cell Mol Physiol. 2002
PubMed ID: 11741821
Splenic T zone development is B cell dependent.
Ngo VN, Cornall RJ, Cyster JG
J Exp Med. 2001
PubMed ID: 11733579
TCR beta chain influences but does not solely control autoreactivity of V alpha 14J281T cells.
Gui M, Li J, Wen LJ, Hardy RR, Hayakawa K
J Immunol. 2001
PubMed ID: 11714786
Role for T cell-independent B cell activity in the resolution of primary rotavirus infection in mice.
VanCott JL, McNeal MM, Flint J, Bailey SA, Choi AH, Ward RL
Eur J Immunol. 2001
PubMed ID: 11745356
Immunobiological analysis of TCR single-chain transgenic mice reveals new possibilities for interaction between CDR3alpha and an antigenic peptide bound to MHC class I.
Zhang W, Honda S, Wang F, DiLorenzo TP, Kalergis AM, Ostrov DA, Nathenson SG
J Immunol. 2001
PubMed ID: 11591764
Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice.
Kamal M, Wakelin D, Ouellette AJ, Smith A, Podolsky DK, Mahida YR
Clin Exp Immunol. 2001
PubMed ID: 11678907
Comparative genomics of the human and mouse T cell receptor loci.
Glusman G, Rowen L, Lee I, Boysen C, Roach JC, Smit AF, Wang K, Koop BF, Hood L
Immunity. 2001
PubMed ID: 11567625
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.
Chitnis T, Najafian N, Benou C, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ
J Clin Invest. 2001
PubMed ID: 11544280
Helicobacter-induced inflammatory bowel disease in IL-10- and T cell-deficient mice.
Burich A, Hershberg R, Waggie K, Zeng W, Brabb T, Westrich G, Viney JL, Maggio-Price L
Am J Physiol Gastrointest Liver Physiol. 2001
PubMed ID: 11518689
Intrinsic AHR in IL-5 transgenic mice is dependent on CD4(+) cells and CD49d-mediated signaling.
Borchers MT, Crosby J, Justice P, Farmer S, Hines E, Lee JJ, Lee NA
Am J Physiol Lung Cell Mol Physiol. 2001
PubMed ID: 11504693
Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus.
Sieh P, Chen J
J Immunol. 2001
PubMed ID: 11489996
Identification of quantitative trait loci controlling activation of TRBV4 CD8+ T cells during murine gamma-herpesvirus-induced infectious mononucleosis.
Hardy CL, Lu L, Nguyen P, Woodland DL, Williams RW, Blackman MA
Immunogenetics. 2001
PubMed ID: 11486276
A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity.
McHugh RS, Shevach EM, Margulies DH, Natarajan K
Eur J Immunol. 2001
PubMed ID: 11449363
IgA production without mu or delta chain expression in developing B cells.
Macpherson AJ, Lamarre A, McCoy K, Harriman GR, Odermatt B, Dougan G, Hengartner H, Zinkernagel RM
Nat Immunol. 2001
PubMed ID: 11429547
Cutting edge: germinal centers can be induced in the absence of T cells.
Lentz VM, Manser T
J Immunol. 2001
PubMed ID: 11418626
Innate immunity to viruses: control of vaccinia virus infection by gamma delta T cells.
Selin LK, Santolucito PA, Pinto AK, Szomolanyi-Tsuda E, Welsh RM
J Immunol. 2001
PubMed ID: 11359837
Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice.
Kado S, Uchida K, Funabashi H, Iwata S, Nagata Y, Ando M, Onoue M, Matsuoka Y, Ohwaki M, Morotomi M
Cancer Res. 2001
PubMed ID: 11289103
Regulation of experimental autoimmune encephalomyelitis in the C57BL/6J mouse by NK1.1+, DX5+, alpha beta+ T cells.
Fritz RB, Zhao ML
J Immunol. 2001
PubMed ID: 11238673
Aged mice exhibit in vivo defective peripheral clonal deletion of D(b)/H-Y reactive CD8(+) T cells.
Hsu HC, Zhou T, Shi J, Yang PA, Liu D, Zhang HG, Bluethmann H, Mountz JD
Mech Ageing Dev. 2001
PubMed ID: 11311318
Interleukin-8 receptor deficiency confers susceptibility to acute pyelonephritis.
Frendéus B, Godaly G, Hang L, Karpman D, Svanborg C
J Infect Dis. 2001
PubMed ID: 11171016
Normal TCRbeta transcription and recombination in the absence of the Jbeta2-Cbeta2 intronic cis element.
Whitehurst CE, Hu H, Ryu CJ, Rajendran P, Schmidt T, Chen J
Mol Immunol. 2001
PubMed ID: 11483210
Establishment of a Tcrb and Trp53 genes deficient mouse strain as an animal model for spontaneous colorectal cancer.
Funabashi H, Uchida K, Kado S, Matsuoka Y, Ohwaki M
Exp Anim. 2001
PubMed ID: 11326422
Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor alphabeta mutant mice.
Chin EY, Dangler CA, Fox JG, Schauer DB
Comp Med. 2000
PubMed ID: 11200563
Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion.
Bouneaud C, Kourilsky P, Bousso P
Immunity. 2000
PubMed ID: 11163198
Depletion of a gamma delta T cell subset can increase host resistance to a bacterial infection.
O'Brien RL, Yin X, Huber SA, Ikuta K, Born WK
J Immunol. 2000
PubMed ID: 11086087
The mouse Kell blood group gene (Kel): cDNA sequence, genomic organization, expression, and enzymatic function.
Lee S, Russo DC, Pu J, Ho M, Redman CM
Immunogenetics. 2000
PubMed ID: 11132157
Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms.
Whitehurst CE, Schlissel MS, Chen J
Immunity. 2000
PubMed ID: 11114382
NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development.
Voll RE, Jimi E, Phillips RJ, Barber DF, Rincon M, Hayday AC, Flavell RA, Ghosh S
Immunity. 2000
PubMed ID: 11114380
Self-limiting systemic autoimmune disease during reconstitution of T cell-deficient mice with syngeneic T cells: support for a multifaceted role of T cells in the maintenance of peripheral B cell tolerance.
Lentz VM, Manser T
Int Immunol. 2000
PubMed ID: 11058568
Genetic dissection of primary and secondary responses to a widespread natural pathogen of the gut, Eimeria vermiformis.
Smith AL, Hayday AC
Infect Immun. 2000
PubMed ID: 11035735
Development of dendritic epidermal T cells with a skewed diversity of gamma delta TCRs in V delta 1-deficient mice.
Hara H, Kishihara K, Matsuzaki G, Takimoto H, Tsukiyama T, Tigelaar RE, Nomoto K
J Immunol. 2000
PubMed ID: 11034374
The mechanism of phospholipase C-gamma1 regulation.
Kim MJ, Kim E, Ryu SH, Suh PG
Exp Mol Med. 2000
PubMed ID: 11048639
BCL-6 regulates chemokine gene transcription in macrophages.
Toney LM, Cattoretti G, Graf JA, Merghoub T, Pandolfi PP, Dalla-Favera R, Ye BH, Dent AL
Nat Immunol. 2000
PubMed ID: 10973278
Gamma delta-T cells are critical for survival and early proinflammatory cytokine gene expression during murine Klebsiella pneumonia.
Moore TA, Moore BB, Newstead MW, Standiford TJ
J Immunol. 2000
PubMed ID: 10946293
Response of murine gamma delta T cells to the synthetic polypeptide poly-Glu50Tyr50.
Cady CT, Lahn M, Vollmer M, Tsuji M, Seo SJ, Reardon CL, O'Brien RL, Born WK
J Immunol. 2000
PubMed ID: 10925256
Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment.
Tsuji RF, Kawikova I, Ramabhadran R, Akahira-Azuma M, Taub D, Hugli TE, Gerard C, Askenase PW
J Immunol. 2000
PubMed ID: 10903768
T cell development in TCR beta enhancer-deleted mice: implications for alpha beta T cell lineage commitment and differentiation.
Leduc I, Hempel WM, Mathieu N, Verthuy C, Bouvier G, Watrin F, Ferrier P
J Immunol. 2000
PubMed ID: 10903739
A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria.
Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM
Science. 2000
PubMed ID: 10864873
Common cytokine receptor gamma chain (gammac)-deficient B cells persist in T cell-deficient gammac-mice and respond to a T-independent antigen.
Vosshenrich CA, Sharara LI, Guy-Grand D, Rajewsky K, Müller W, Di Santo JP
Eur J Immunol. 2000
PubMed ID: 10898497
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.
Bassing CH, Alt FW, Hughes MM, D'Auteuil M, Wehrly TD, Woodman BB, Gärtner F, White JM, Davidson L, Sleckman BP
Nature. 2000
PubMed ID: 10850719
Induction of CD4(+) T-cell-independent immunoglobulin responses by inactivated influenza virus.
Sha Z, Compans RW
J Virol. 2000
PubMed ID: 10799573
gammadelta T cells may dichotomously modulate infection with avirulent Salmonella choleraesuis via IFN-gamma and IL-13 in mice.
Naiki Y, Nishimura H, Itohara S, Yoshikai Y
Cell Immunol. 2000
PubMed ID: 10873307
The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system.
Gray TA, Hernandez L, Carey AH, Schaldach MA, Smithwick MJ, Rus K, Marshall Graves JA, Stewart CL, Nicholls RD
Genomics. 2000
PubMed ID: 10843807
Role of gut cryptopatches in early extrathymic maturation of intestinal intraepithelial T cells.
Oida T, Suzuki K, Nanno M, Kanamori Y, Saito H, Kubota E, Kato S, Itoh M, Kaminogawa S, Ishikawa H
J Immunol. 2000
PubMed ID: 10725718
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice.
Kennedy MK, Glaccum M, Brown SN, Butz EA, Viney JL, Embers M, Matsuki N, Charrier K, Sedger L, Willis CR, Brasel K, Morrissey PJ, Stocking K, Schuh JC, Joyce S, Peschon JJ
J Exp Med. 2000
PubMed ID: 10704459
NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.
Coles MC, Raulet DH
J Immunol. 2000
PubMed ID: 10679077
Proinflammatory roles of T-cell receptor (TCR)gammadelta and TCRalphabeta lymphocytes in a murine model of asthma.
Schramm CM, Puddington L, Yiamouyiannis CA, Lingenheld EG, Whiteley HE, Wolyniec WW, Noonan TC, Thrall RS
Am J Respir Cell Mol Biol. 2000
PubMed ID: 10657943
Association study of proposed candidate genes/regions in a population of Spanish asthmatics.
Soriano JB, de Cid R, Estivill X, Antó JM, Sunyer J, Otero D, Roca J, Rodríguez-Roisín R, Morell F, Rodrigo MJ, Ercilla G, Beaty TH, Lázaro C
Eur J Epidemiol. 2000
PubMed ID: 11142503
Protein displays of the human T cell receptor alpha, beta, gamma and delta variable and joining regions.
Folch G, Scaviner D, Contet V, Lefranc MP
Exp Clin Immunogenet. 2000
PubMed ID: 11096259
Organogenic role of B lymphocytes in mucosal immunity.
Golovkina TV, Shlomchik M, Hannum L, Chervonsky A
Science. 1999
PubMed ID: 10583962
Impaired NK1.1 T cell development in mice transgenic for a T cell receptor beta chain lacking the large, solvent-exposed cbeta FG loop.
Degermann S, Sollami G, Karjalainen K
J Exp Med. 1999
PubMed ID: 10544207
Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros.
Winandy S, Wu L, Wang JH, Georgopoulos K
J Exp Med. 1999
PubMed ID: 10523602
Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells.
Lahn M, Kanehiro A, Takeda K, Joetham A, Schwarze J, Köhler G, O'Brien R, Gelfand EW, Born W, Kanehio A
Nat Med. 1999
PubMed ID: 10502818
Susceptibility to myocarditis is dependent on the response of alphabeta T lymphocytes to coxsackieviral infection.
Opavsky MA, Penninger J, Aitken K, Wen WH, Dawood F, Mak T, Liu P
Circ Res. 1999
PubMed ID: 10488058
Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells.
Steinhoff U, Brinkmann V, Klemm U, Aichele P, Seiler P, Brandt U, Bland PW, Prinz I, Zügel U, Kaufmann SH
Immunity. 1999
PubMed ID: 10514013
Regulatory role of peritoneal NK1.1+ alpha beta T cells in IL-12 production during Salmonella infection.
Naiki Y, Nishimura H, Kawano T, Tanaka Y, Itohara S, Taniguchi M, Yoshikai Y
J Immunol. 1999
PubMed ID: 10438944
Effect on parasite eradication of Pneumocystis carinii-specific antibodies produced in the presence or absence of CD4(+) alphabeta T lymphocytes.
Hanano R, Kaufmann SH
Eur J Immunol. 1999
PubMed ID: 10458760
Cellular immune responses are essential for the development of Helicobacter felis-associated gastric pathology.
Roth KA, Kapadia SB, Martin SM, Lorenz RG
J Immunol. 1999
PubMed ID: 10415051
In vivo polysaccharide-specific IgG isotype responses to intact Streptococcus pneumoniae are T cell dependent and require CD40- and B7-ligand interactions.
Wu ZQ, Vos Q, Shen Y, Lees A, Wilson SR, Briles DE, Gause WC, Mond JJ, Snapper CM
J Immunol. 1999
PubMed ID: 10395655
Collagen-induced arthritis development requires alpha beta T cells but not gamma delta T cells: studies with T cell-deficient (TCR mutant) mice.
Corthay A, Johansson A, Vestberg M, Holmdahl R
Int Immunol. 1999
PubMed ID: 10383939
Cytolytic and IFN-gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are T cell receptor-beta-chain dependent.
Kohyama M, Nanno M, Kawaguchi-Miyashita M, Shimada S, Watanabe M, Hibi T, Kaminogawa S, Ishikawa H
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10377435
A central role for alpha beta T cells in the pathogenesis of murine lupus.
Seery JP, Wang EC, Cattell V, Carroll JM, Owen MJ, Watt FM
J Immunol. 1999
PubMed ID: 10358171
Colitis in transgenic and knockout animals as models of human inflammatory bowel disease.
Bhan AK, Mizoguchi E, Smith RN, Mizoguchi A
Immunol Rev. 1999
PubMed ID: 10450518
Absolute requirement for the pre-T cell receptor alpha chain during NK1.1+ TCRalphabeta cell development.
Eberl G, Fehling HJ, von Boehmer H, MacDonald HR
Eur J Immunol. 1999
PubMed ID: 10382759
T cell receptor beta chain lacking the large solvent-exposed Cbeta FG loop supports normal alpha/beta T cell development and function in transgenic mice.
Degermann S, Sollami G, Karjalainen K
J Exp Med. 1999
PubMed ID: 10330447
The bHLH gene Hes1 is essential for expansion of early T cell precursors.
Tomita K, Hattori M, Nakamura E, Nakanishi S, Minato N, Kageyama R
Genes Dev. 1999
PubMed ID: 10323870
Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter.
Whitehurst CE, Chattopadhyay S, Chen J
Immunity. 1999
PubMed ID: 10204487
Reduced generation but efficient TCR beta-chain selection of CD4+8+ double-positive thymocytes in mice with compromised CD3 complex signaling.
Würch A, Biro J, Falk I, Mossmann H, Eichmann K
J Immunol. 1999
PubMed ID: 10072519
Characterization of TCR gene rearrangements during adult murine T cell development.
Livák F, Tourigny M, Schatz DG, Petrie HT
J Immunol. 1999
PubMed ID: 10072498
Lymph node germinal centers form in the absence of follicular dendritic cell networks.
Koni PA, Flavell RA
J Exp Med. 1999
PubMed ID: 10049949
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen.
Ngo VN, Korner H, Gunn MD, Schmidt KN, Riminton DS, Cooper MD, Browning JL, Sedgwick JD, Cyster JG
J Exp Med. 1999
PubMed ID: 9892622
The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model.
Girgis L, Davis MM, Fazekas de St Groth B
J Exp Med. 1999
PubMed ID: 9892609
Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells.
Endres R, Alimzhanov MB, Plitz T, Fütterer A, Kosco-Vilbois MH, Nedospasov SA, Rajewsky K, Pfeffer K
J Exp Med. 1999
PubMed ID: 9874572
Chronic intravenous injections of antigen induce and maintain tolerance in T cell receptor-transgenic mice.
Bercovici N, Delon J, Cambouris C, Escriou N, Debré P, Liblau RS
Eur J Immunol. 1999
PubMed ID: 9933117
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.
Azzam HS, Grinberg A, Lui K, Shen H, Shores EW, Love PE
J Exp Med. 1998
PubMed ID: 9858516
IL-12 enhances antibody responses to T-independent polysaccharide vaccines in the absence of T and NK cells.
Buchanan RM, Arulanandam BP, Metzger DW
J Immunol. 1998
PubMed ID: 9820529
Characteristics of the strong antibody response to mycobacterial Hsp70: a primary, T cell-dependent IgG response with no evidence of natural priming or gamma delta T cell involvement.
Bonorino C, Nardi NB, Zhang X, Wysocki LJ
J Immunol. 1998
PubMed ID: 9820492
Chromosomal localization of the human and murine orthologues of the Drosophila smoothened gene.
Chidambaram A, Gerrard B, Hanson M, Dean M
Genomics. 1998
PubMed ID: 9799615
Molecular cloning and chromosomal localization of the mouse Gpr37 gene encoding an orphan G-protein-coupled peptide receptor expressed in brain and testis.
Marazziti D, Gallo A, Golini E, Matteoni R, Tocchini-Valentini GP
Genomics. 1998
PubMed ID: 9799598
A mouse carrying genetic defect in the choice between T and B lymphocytes.
Tokoro Y, Sugawara T, Yaginuma H, Nakauchi H, Terhorst C, Wang B, Takahama Y
J Immunol. 1998
PubMed ID: 9794386
Emergence of TCR alpha/beta V(D)J recombination and transcription during ontogeny of inbred mouse strains.
Junta CM, Passos GA
Mol Cell Biochem. 1998
PubMed ID: 9788744
Thymic heterotypic cellular complexes in gene-targeted mice with defined blocks in T cell development and adhesion molecule expression.
Oliveira-dos-Santos AJ, Penninger JM, Rieker-Geley T, Matsumoto G, Mak TM, Wick G
Eur J Immunol. 1998
PubMed ID: 9754575
Acute and relapsing experimental autoimmune encephalomyelitis in IL-4- and alpha/beta T cell-deficient C57BL/6 mice.
Zhao ML, Fritz RB
J Neuroimmunol. 1998
PubMed ID: 9670859
Regulation of Vbeta germline transcription in RAG-deficient mice by the CD3epsilon-mediated signals: implication of Vbeta transcriptional regulation in TCR beta allelic exclusion.
Senoo M, Shinkai Y
Int Immunol. 1998
PubMed ID: 9645603
B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion.
Fu YX, Huang G, Wang Y, Chaplin DD
J Exp Med. 1998
PubMed ID: 9529317
The developmental fate of T cells is critically influenced by TCRgammadelta expression.
Kang J, Coles M, Cado D, Raulet DH
Immunity. 1998
PubMed ID: 9586633
Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
Ding YH, Smith KJ, Garboczi DN, Utz U, Biddison WE, Wiley DC
Immunity. 1998
PubMed ID: 9586631
The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.
Haks MC, Krimpenfort P, Borst J, Kruisbeek AM
EMBO J. 1998
PubMed ID: 9524111
The induction of a protective response in Leishmania major-infected BALB/c mice with anti-CD40 mAb.
Ferlin WG, von der Weid T, Cottrez F, Ferrick DA, Coffman RL, Howard MC
Eur J Immunol. 1998
PubMed ID: 9521062
Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus.
Aifantis I, Buer J, von Boehmer H, Azogui O
Immunity. 1997
PubMed ID: 9390684
Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides.
Grubin CE, Kovats S, deRoos P, Rudensky AY
Immunity. 1997
PubMed ID: 9285405
Shared TCR Vbeta gene expression by the pancreas and salivary gland in immunodeficient alymphoplasic mice.
Yamamichi M, Matsuoka N, Tomioka T, Eguchi K, Nagataki S, Kanematsu T
J Immunol. 1997
PubMed ID: 9200482
Short-term dexamethasone treatment modulates the expression of the murine TCR zeta gene locus.
Ronchetti S, Nocentini G, Giunchi L, Bartoli A, Moraca R, Riccardi C, Migliorati G
Cell Immunol. 1997
PubMed ID: 9225003
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development.
Wiest DL, Ashe JM, Howcroft TK, Lee HM, Kemper DM, Negishi I, Singer DS, Singer A, Abe R
Immunity. 1997
PubMed ID: 9208839
Association between susceptibility to Theiler's virus-induced demyelination and T-cell receptor Jbeta1-Cbeta1 polymorphism rather than Vbeta deletion.
Bahk YY, Kappel CA, Rasmussen G, Kim BS
J Virol. 1997
PubMed ID: 9094705
Deregulated TCR alpha beta T cell population provokes extramedullary hematopoiesis in mice deficient in the common gamma chain.
Sharara LI, Andersson A, Guy-Grand D, Fischer A, DiSanto JP
Eur J Immunol. 1997
PubMed ID: 9130655
Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.
Perry LL, Feilzer K, Caldwell HD
J Immunol. 1997
PubMed ID: 9120292
Early alpha beta T cell development in the thymus of normal and genetically altered mice.
Fehling HJ, von Boehmer H
Curr Opin Immunol. 1997
PubMed ID: 9099797
CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.
Dave VP, Cao Z, Browne C, Alarcon B, Fernandez-Miguel G, Lafaille J, de la Hera A, Tonegawa S, Kappes DJ
EMBO J. 1997
PubMed ID: 9135151
Gamma 2b provides only some of the signals normally given via mu in B cell development.
Kurtz BS, Witte PL, Storb U
Int Immunol. 1997
PubMed ID: 9088980
T cell-mediated elimination of B7.2 transgenic B cells.
Fournier S, Rathmell JC, Goodnow CC, Allison JP
Immunity. 1997
PubMed ID: 9075933
alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity.
Peng SL, McNiff JM, Madaio MP, Ma J, Owen MJ, Flavell RA, Hayday AC, Craft J
J Immunol. 1997
PubMed ID: 9036998
Structure and function of the pre-T cell receptor.
von Boehmer H, Fehling HJ
Annu Rev Immunol. 1997
PubMed ID: 9143695
T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment.
Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Owen MJ
Am J Pathol. 1997
PubMed ID: 9006326
A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness.
Bäckström BT, Milia E, Peter A, Jaureguiberry B, Baldari CT, Palmer E
Immunity. 1996
PubMed ID: 8934571
T-cell alpha beta + and gamma delta + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium.
Roberts SJ, Smith AL, West AB, Wen L, Findly RC, Owen MJ, Hayday AC
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8876213
Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells.
Pao W, Wen L, Smith AL, Gulbranson-Judge A, Zheng B, Kelsoe G, MacLennan IC, Owen MJ, Hayday AC
Curr Biol. 1996
PubMed ID: 8939571
Genes for murine Y1 and Y3 Ro RNAs have class 3 RNA polymerase III promoter structures and are unlinked on mouse chromosome 6.
Farris AD, Gross JK, Hanas JS, Harley JB
Gene. 1996
PubMed ID: 8863726
Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase.
Pani G, Fischer KD, Mlinaric-Rascan I, Siminovitch KA
J Exp Med. 1996
PubMed ID: 9064344
A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice.
Peng SL, Robert ME, Hayday AC, Craft J
J Exp Med. 1996
PubMed ID: 9064331
Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.
Ben-Arie N, McCall AE, Berkman S, Eichele G, Bellen HJ, Zoghbi HY
Hum Mol Genet. 1996
PubMed ID: 8872459
Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment.
Huleatt JW, Lefrançois L
Immunity. 1996
PubMed ID: 8808681
Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii.
Liesenfeld O, Kosek J, Remington JS, Suzuki Y
J Exp Med. 1996
PubMed ID: 8760813
Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development.
Bouvier G, Watrin F, Naspetti M, Verthuy C, Naquet P, Ferrier P
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8755570
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.
Rowen L, Koop BF, Hood L
Science. 1996
PubMed ID: 8650574
Functions of TCR and pre-TCR subunits: lessons from gene ablation.
Malissen B, Malissen M
Curr Opin Immunol. 1996
PubMed ID: 8793999
Oncogenic potential of a pre-T cell receptor lacking the TCR beta variable domain.
Jacobs H, Ossendorp F, de Vries E, Ungewiss K, von Boehmer H, Borst J, Berns A
Oncogene. 1996
PubMed ID: 8668334
Murine lupus in the absence of alpha beta T cells.
Peng SL, Madaio MP, Hughes DP, Crispe IN, Owen MJ, Wen L, Hayday AC, Craft J
J Immunol. 1996
PubMed ID: 8621947
Il-7 supports D-J but not V-DJ rearrangement of TCR-beta gene in fetal liver progenitor cells.
Tsuda S, Rieke S, Hashimoto Y, Nakauchi H, Takahama Y
J Immunol. 1996
PubMed ID: 8617945
T cell receptor-gamma, delta-expressing fetal mouse thymocytes are generated without T cell receptor V beta selection.
Mertsching E, Ceredig R
Eur J Immunol. 1996
PubMed ID: 8625971
The specificity and orientation of a TCR to its peptide-MHC class II ligands.
Sant'Angelo DB, Waterbury G, Preston-Hurlburt P, Yoon ST, Medzhitov R, Hong SC, Janeway CA
Immunity. 1996
PubMed ID: 8612131
Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts.
Guthridge MA, Seldin M, Basilico C
Oncogene. 1996
PubMed ID: 8649829
p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes.
Bogue MA, Zhu C, Aguilar-Cordova E, Donehower LA, Roth DB
Genes Dev. 1996
PubMed ID: 8598286
Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias.
Nakamura T, Largaespada DA, Shaughnessy JD, Jenkins NA, Copeland NG
Nat Genet. 1996
PubMed ID: 8563752
Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes.
Li T, Ramirez K, Palacios R
Cell Growth Differ. 1996
PubMed ID: 8788039
The genetic mapping and gene structure of mouse paraoxonase/arylesterase.
Sorenson RC, Primo-Parmo SL, Camper SA, La Du BN
Genomics. 1995
PubMed ID: 8825627
The mouse aquaporin-1 gene.
Moon C, Williams JB, Preston GM, Copeland NG, Gilbert DJ, Nathans D, Jenkins NA, Agre P
Genomics. 1995
PubMed ID: 8586439
An anchored molecular map of mouse chromosome 6 with an analysis of interference.
Davies PO, Melanitou E, Asano M, Avner PR, Montagutelli X
Mamm Genome. 1995
PubMed ID: 8563173
Expression of genes encoding the pre-TCR and CD3 complex during thymus development.
Wilson A, MacDonald HR
Int Immunol. 1995
PubMed ID: 8562511
Incomplete T cell receptor V beta allelic exclusion and dual V beta-expressing cells.
Balomenos D, Balderas RS, Mulvany KP, Kaye J, Kono DH, Theofilopoulos AN
J Immunol. 1995
PubMed ID: 7561023
Different susceptibility to lung tumorigenesis in mice with an identical Kras2 intron 2.
Manenti G, Falvella FS, Gariboldi M, Dragani TA, Pierotti MA
Genomics. 1995
PubMed ID: 8666392
Control of thymus-independent intestinal intraepithelial lymphocytes by beta 2-microglobulin.
Neuhaus O, Emoto M, Blum C, Yamamoto S, Kaufmann SH
Eur J Immunol. 1995
PubMed ID: 7664795
V(D)J recombination and allelic exclusion of a TCR beta-chain minilocus occurs in the absence of a functional promoter.
Alvarez JD, Anderson SJ, Loh DY
J Immunol. 1995
PubMed ID: 7636187
The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome.
Miyazaki S, Kozak CA, Marchetti A, Buttitta F, Gallahan D, Callahan R
Genomics. 1995
PubMed ID: 7558022
Regulation of early T cell development by the engagement of TCR-beta complex expressed on fetal thymocytes from TCR-beta-transgenic scid mice.
Takahama Y, Sugaya K, Tsuda S, Hasegawa T, Hashimoto Y
J Immunol. 1995
PubMed ID: 7751632
Localization of the thyrotropin-releasing hormone gene, Trh, on mouse chromosome 6.
Roller ML, Camper SA
Mamm Genome. 1995
PubMed ID: 7647472
Alpha beta and gamma delta T cells can share a late common precursor.
Dudley EC, Girardi M, Owen MJ, Hayday AC
Curr Biol. 1995
PubMed ID: 7552177
Junctional region of the myelin basic protein-specific T cell receptor beta chain in mice.
Kalman B, Alder H, Knobler RL
J Neuroimmunol. 1995
PubMed ID: 7541056
T cell development in TCR-alpha beta transgenic mice. Analysis using V(D)J recombination substrates.
Capone M, Curnow J, Bouvier G, Ferrier P, Horvat B
J Immunol. 1995
PubMed ID: 7730622
CD1 recognition by mouse NK1+ T lymphocytes.
Bendelac A, Lantz O, Quimby ME, Yewdell JW, Bennink JR, Brutkiewicz RR
Science. 1995
PubMed ID: 7538697
Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway.
Guidos CJ, Williams CJ, Wu GE, Paige CJ, Danska JS
J Exp Med. 1995
PubMed ID: 7869035
Contribution of alpha/beta and gamma/delta T lymphocytes to immunity against Mycobacterium bovis bacillus Calmette Guérin: studies with T cell receptor-deficient mutant mice.
Ladel CH, Hess J, Daugelat S, Mombaerts P, Tonegawa S, Kaufmann SH
Eur J Immunol. 1995
PubMed ID: 7705416
Mouse T-cell receptor variable gene segment families.
Arden B, Clark SP, Kabelitz D, Mak TW
Immunogenetics. 1995
PubMed ID: 8550093
Human T-cell receptor variable gene segment families.
Arden B, Clark SP, Kabelitz D, Mak TW
Immunogenetics. 1995
PubMed ID: 8550092
Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1).
Kozak CA, Gatignol A, Graham K, Jeang KT, McBride OW
Genomics. 1995
PubMed ID: 7774957
Germline transcription and expression of Tcrb-V8 genes in peripheral mouse lymphoid tissues.
O'Neill HC, Jolly CJ
Immunogenetics. 1995
PubMed ID: 7590963
Lymphocyte development and function in T-cell receptor and RAG-1 mutant mice.
Mombaerts P
Int Rev Immunol. 1995
PubMed ID: 7494108
Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene.
Yamin M, Gorn AH, Flannery MR, Jenkins NA, Gilbert DJ, Copeland NG, Tapp DR, Krane SM, Goldring SR
Endocrinology. 1994
PubMed ID: 7988453
Analysis and expression of a cloned pre-T cell receptor gene.
Saint-Ruf C, Ungewiss K, Groettrup M, Bruno L, Fehling HJ, von Boehmer H
Science. 1994
PubMed ID: 7973703
Genetic mapping of two mouse homeobox genes Tlx-1 and Tlx-2 to murine chromosomes 19 and 6.
Wen XY, Tang S, Breitman ML
Genomics. 1994
PubMed ID: 7698766
Engineering and expression of a secreted murine TCR with reduced N-linked glycosylation.
Strong RK, Penny DM, Feldman RM, Weiner LP, Boniface JJ, Davis MM, Bjorkman PJ
J Immunol. 1994
PubMed ID: 7930615
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice.
Lafaille JJ, Nagashima K, Katsuki M, Tonegawa S
Cell. 1994
PubMed ID: 7520367
Heterogeneity and biased T cell receptor alpha/beta repertoire of mucosal CD8+ cells from murine large intestine: implications for functional state.
Ibraghimov AR, Lynch RG
J Exp Med. 1994
PubMed ID: 8046326
Mapping of mouse intracisternal A-particle proviral markers in an interspecific backcross.
Lueders KK, Frankel WN
Mamm Genome. 1994
PubMed ID: 7949730
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.
Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA
Genes Dev. 1994
PubMed ID: 7958843
Differential expression of activation markers during tolerance induction by superantigens in T-cell receptor (beta-chain) transgenic mice.
Perkins DL, Listman JA, Wang Y, Ho SS, Finn PW, Rimm IJ
Cell Immunol. 1994
PubMed ID: 8025950
CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.
Shinkai Y, Alt FW
Int Immunol. 1994
PubMed ID: 7947468
Peripheral lymphoid development and function in TCR mutant mice.
Mombaerts P, Mizoguchi E, Ljunggren HG, Iacomini J, Ishikawa H, Wang L, Grusby MJ, Glimcher LH, Winn HJ, Bhan AK
Int Immunol. 1994
PubMed ID: 7947457
Genetic mapping of 40 cDNA clones on the mouse genome by PCR.
Ko MS, Wang X, Horton JH, Hagen MD, Takahashi N, Maezaki Y, Nadeau JH
Mamm Genome. 1994
PubMed ID: 8043949
Pro-T cells in fetal thymus express c-kit and RAG-2 but do not rearrange the gene encoding the T cell receptor beta chain.
Hozumi K, Kobori A, Sato T, Nozaki H, Nishikawa S, Nishimura T, Habu S
Eur J Immunol. 1994
PubMed ID: 7515811
Comparative mapping of the actin-binding protein 280 genes in human and mouse.
Gariboldi M, Maestrini E, Canzian F, Manenti G, De Gregorio L, Rivella S, Chatterjee A, Herman GE, Archidiacono N, Antonacci R
Genomics. 1994
PubMed ID: 8088838
Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.
Godfrey DI, Kennedy J, Mombaerts P, Tonegawa S, Zlotnik A
J Immunol. 1994
PubMed ID: 7513723
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.
Rowe LB, Nadeau JH, Turner R, Frankel WN, Letts VA, Eppig JT, Ko MS, Thurston SJ, Birkenmeier EH
Mamm Genome. 1994
PubMed ID: 8075499
T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice.
Dudley EC, Petrie HT, Shah LM, Owen MJ, Hayday AC
Immunity. 1994
PubMed ID: 7534200
Holes in the T cell repertoire to myelin basic protein owing to the absence of the D beta 2-J beta 2 gene cluster: implications for T cell receptor recognition and autoimmunity.
Kumar V, Sercarz E
J Exp Med. 1994
PubMed ID: 7513012
The genes encoding the somatic and testis-specific isotypes of the mouse cytochrome c genes map to paralogous regions of chromosomes 6 and 2.
Hake LE, Kuemmerle N, Hecht NB, Kozak CA
Genomics. 1994
PubMed ID: 8034327
Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon.
Levelt CN, Mombaerts P, Iglesias A, Tonegawa S, Eichmann K
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8248261
Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.
Klocke R, Roberds SL, Tamkun MM, Gronemeier M, Augustin A, Albrecht B, Pongs O, Jockusch H
Genomics. 1993
PubMed ID: 7905852
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice.
Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S
Cell. 1993
PubMed ID: 8104709
Characterization of murine T cell responses to peptides of the variable region of self T cell receptor beta-chains.
MacNeil D, Fraga E, Singh B
J Immunol. 1993
PubMed ID: 8409384
Protein tyrosine kinase p56lck controls allelic exclusion of T-cell receptor beta-chain genes.
Anderson SJ, Levin SD, Perlmutter RM
Nature. 1993
PubMed ID: 8413611
Is TCR beta expression an essential event in early thymocyte development?
Palmer DB, Hayday A, Owen MJ
Immunol Today. 1993
PubMed ID: 8216724
Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene.
Muegge K, Vila MP, Durum SK
Science. 1993
PubMed ID: 7686307
GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function.
Godfrey P, Rahal JO, Beamer WG, Copeland NG, Jenkins NA, Mayo KE
Nat Genet. 1993
PubMed ID: 8395283
T cell receptor beta chain dimers on immature thymocytes from normal mice.
Groettrup M, von Boehmer H
Eur J Immunol. 1993
PubMed ID: 8500533
mnd2: a new mouse model of inherited motor neuron disease.
Jones JM, Albin RL, Feldman EL, Simin K, Schuster TG, Dunnick WA, Collins JT, Chrisp CE, Taylor BA, Meisler MH
Genomics. 1993
PubMed ID: 8325640
Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6.
Sudweeks JD, Todd JA, Blankenhorn EP, Wardell BB, Woodward SR, Meeker ND, Estes SS, Teuscher C
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8475118
Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.
Zhou T, Bluethmann H, Eldridge J, Berry K, Mountz JD
J Immunol. 1993
PubMed ID: 7682246
The short 3'-end region of complementary DNAs as PCR-based polymorphic markers for an expression map of the mouse genome.
Takahashi N, Ko MS
Genomics. 1993
PubMed ID: 8486351
T cell receptor V beta gene utilization in myelin basic protein specific clones from CXJ1 recombinant inbred mice.
Kalman B, Knobler RL, Lublin FD
J Neuroimmunol. 1993
PubMed ID: 7681448
The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.
Malek TR, Vincek V, Gatalica B, Bucan M
Immunogenetics. 1993
PubMed ID: 8482578
Influence of T-cell receptor genes on chronic experimental autoimmune encephalomyelitis.
Jansson L, Olsson T, Holmdahl R
Immunogenetics. 1993
PubMed ID: 7679665
Characterization of the human pleiotrophin gene. Promoter region and chromosomal localization.
Li YS, Hoffman RM, Le Beau MM, Espinosa R, Jenkins NA, Gilbert DJ, Copeland NG, Deuel TF
J Biol Chem. 1992
PubMed ID: 1464612
Evidence for a role for T cell receptors (TCR) in the effector phase of acute bone marrow graft rejection. TCR V beta 5 transgenic mice lack effector cells able to cause graft rejection.
Kikly K, Dennert G
J Immunol. 1992
PubMed ID: 1431119
Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame protein.
Acha-Orbea H, Scarpellino L, Shakhov AN, Held W, MacDonald HR
J Exp Med. 1992
PubMed ID: 1334118
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.
Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafaille JJ, Wang L, Ichikawa Y, Jaenisch R, Hooper ML
Nature. 1992
PubMed ID: 1359428
Anti-TCR-V beta 6 breaks tolerance in female AKR, Mlsa mice inducing foetal lethality.
de Giorgi L, Matossian-Rogers A
Immunol Lett. 1992
PubMed ID: 1428006
Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome.
Bahary N, Pachter JE, Felman R, Leibel RL, Albright K, Cram S, Friedman JM
Genomics. 1992
PubMed ID: 1639403
T cell receptor-alpha beta lacking the beta-chain V domain can be expressed at the cell surface but prohibits T cell maturation.
Ossendorp F, Jacobs H, van der Horst G, de Vries E, Berns A, Borst J
J Immunol. 1992
PubMed ID: 1351085
Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells.
Philpott KL, Viney JL, Kay G, Rastan S, Gardiner EM, Chae S, Hayday AC, Owen MJ
Science. 1992
PubMed ID: 1604321
Analysis of TCR V beta gene usage and encephalitogenicity of myelin basic protein peptide p91-103 reactive T cell clones in SJL mice: lack of evidence for V gene hypothesis.
Su XM, Sriram S
Cell Immunol. 1992
PubMed ID: 1374293
Expansion of murine T cells bearing a unique T cell receptor beta-chain in Friend virus-induced tumor in situ.
Suzuki M, Koseki H, Mizutani Y, Kuribayashi K, Kanno M, Taniguchi M
J Immunol. 1992
PubMed ID: 1374106
Lacrimal and salivary gland inflammation in the C3H/Ipr autoimmune strain mouse: a potential mode for Sjögren's syndrome.
Johnson BC, Morton JI, Trune DR
Otolaryngol Head Neck Surg. 1992
PubMed ID: 1565490
Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens.
Adams S, Leblanc P, Datta SK
Proc Natl Acad Sci U S A. 1991
PubMed ID: 1837146
Molecular mapping of the mouse ob mutation.
Friedman JM, Leibel RL, Siegel DS, Walsh J, Bahary N
Genomics. 1991
PubMed ID: 1686014
Inactivation of muscle chloride channel by transposon insertion in myotonic mice.
Steinmeyer K, Klocke R, Ortland C, Gronemeier M, Jockusch H, Gründer S, Jentsch TJ
Nature. 1991
PubMed ID: 1659665
Molecular genetic linkage maps of mouse chromosomes 4 and 6.
Bahary N, Zorich G, Pachter JE, Leibel RL, Friedman JM
Genomics. 1991
PubMed ID: 1684952
Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.
Siracusa LD, Rosner MH, Vigano MA, Gilbert DJ, Staudt LM, Copeland NG, Jenkins NA
Genomics. 1991
PubMed ID: 1676977
Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting.
Mombaerts P, Clarke AR, Hooper ML, Tonegawa S
Proc Natl Acad Sci U S A. 1991
PubMed ID: 1826563
Contribution of the gene linked to the T cell receptor beta chain gene complex of NZW mice to the autoimmunity of (NZB x NZW)F1 mice.
Hirose S, Tokushige K, Kinoshita K, Nozawa S, Saito J, Nishimura H, Shirai T
Eur J Immunol. 1991
PubMed ID: 1826267
An endogenous retrovirus mediating deletion of alpha beta T cells?
Woodland DL, Happ MP, Gollob KJ, Palmer E
Nature. 1991
PubMed ID: 1846949
Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids.
Yasue M, Serikawa T, Yamada J
Cytogenet Cell Genet. 1991
PubMed ID: 1914521
Molecular organization, ontogeny and expression of murine alpha beta and gamma delta T cell receptors.
Penninger J, Wallace VA, Kishihara K, Molina T, Krause H, Mak TW
Exp Clin Immunogenet. 1991
PubMed ID: 1838695
Additional microsatellite markers for mouse genome mapping.
Hearne CM, McAleer MA, Love JM, Aitman TJ, Cornall RJ, Ghosh S, Knight AM, Prins JB, Todd JA
Mamm Genome. 1991
PubMed ID: 1794058
Surface expression of the beta T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells.
Kishi H, Borgulya P, Scott B, Karjalainen K, Traunecker A, Kaufman J, von Boehmer H
EMBO J. 1991
PubMed ID: 1703490
Identification and applications of repetitive probes for gene mapping in the mouse.
Siracusa LD, Jenkins NA, Copeland NG
Genetics. 1991
PubMed ID: 1673105
Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo.
Murphy KM, Heimberger AB, Loh DY
Science. 1990
PubMed ID: 2125367
Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes.
Gottschalk LR, Leiden JM
Mol Cell Biol. 1990
PubMed ID: 2144610
Segregation patterns of endogenous mouse mammary tumor viruses in five recombinant inbred strain sets.
Lee BK, Eicher EM
J Virol. 1990
PubMed ID: 2166832
The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides.
Danska JS, Livingstone AM, Paragas V, Ishihara T, Fathman CG
J Exp Med. 1990
PubMed ID: 1694219
T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.
Ishida I, Verbeek S, Bonneville M, Itohara S, Berns A, Tonegawa S
Proc Natl Acad Sci U S A. 1990
PubMed ID: 2326267
Linkage between Tcrb-V and a gene responsible for deletion of Tcrb-V11+ T cells.
Tomonari K
Immunogenetics. 1990
PubMed ID: 2142677
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen.
Pircher H, Bürki K, Lang R, Hengartner H, Zinkernagel RM
Nature. 1989
PubMed ID: 2573841
Identification of two murine loci homologous to the v-cbl oncogene.
Regnier DC, Kozak CA, Kingsley DM, Jenkins NA, Copeland NG, Langdon WY, Morse HC
J Virol. 1989
PubMed ID: 2760978
Physical maps of the mouse and human immunoglobulin-like loci.
Lai E, Wilson RK, Hood LE
Adv Immunol. 1989
PubMed ID: 2675563
Polymorphism of T-cell receptor genes among laboratory and wild mice: diverse origins of laboratory mice.
Nobuhara H, Kuida K, Furutani M, Shiroishi T, Moriwaki K, Yanagi Y, Tada T
Immunogenetics. 1989
PubMed ID: 2574156
Chromosomal translocation involving the beta T cell receptor gene in acute leukemia.
Cleary ML, Mellentin JD, Spies J, Smith SD
J Exp Med. 1988
PubMed ID: 3162254
Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families.
Wilson RK, Lai E, Concannon P, Barth RK, Hood LE
Immunol Rev. 1988
PubMed ID: 2965094
Mapping of the Ly-4 (L3T4) T-cell differentiation antigen on mouse chromosome 6 by the use of RFLPs in an interspecific cross.
Seldin MF, D'Hoostelaere LA, Huppi K, Mock BA, Steinberg AD, Parnes JR, Morse HC
Immunogenetics. 1988
PubMed ID: 2895734
T-cell receptor VT beta genes in natural populations of mice.
Huppi KE, D'Hoostelaere LA, Mock BA, Jouvin-Marche E, Behlke MA, Chou HS, Berry RJ, Loh DY
Immunogenetics. 1988
PubMed ID: 2890577
Mapping of Igk-V genes using backcrossed laboratory and wild mice.
Rueff-Juy D, Drapier AM, Cazenave PA
Immunogenetics. 1988
PubMed ID: 2843459
Chromosomal localization of the met proto-oncogene in the mouse and cat genome.
Dean M, Kozak C, Robbins J, Callahan R, O'Brien S, Vande Woude GF
Genomics. 1987
PubMed ID: 3692486
A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6.
Mock BA, D'Hoostelaere LA, Matthai R, Huppi K
Genetics. 1987
PubMed ID: 2887485
Variations in genetic control of susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Differences between susceptible SJL/J and resistant BALB/c strains map near the T cell beta-chain constant gene on chromos
Melvold RW, Jokinen DM, Knobler RL, Lipton HL
J Immunol. 1987
PubMed ID: 3027179
Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7.
Bućan M, Yang-Feng T, Colberg-Poley AM, Wolgemuth DJ, Guenet JL, Francke U, Lehrach H
EMBO J. 1986
PubMed ID: 2878803
Delineation of a defect in T cell receptor beta genes of NZW mice predisposed to autoimmunity.
Noonan DJ, Kofler R, Singer PA, Cardenas G, Dixon FJ, Theofilopoulos AN
J Exp Med. 1986
PubMed ID: 3005467
Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.
Emi M, Nakamura Y, Ogawa M, Yamamoto T, Nishide T, Mori T, Matsubara K
Gene. 1986
PubMed ID: 3011602
The complete primary structure of the T-cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone.
Leiden JM, Fraser JD, Strominger JL
Immunogenetics. 1986
PubMed ID: 2426193
Identification of the components of the murine T cell antigen receptor complex.
Samelson LE, Harford JB, Klausner RD
Cell. 1985
PubMed ID: 3878228
The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.
Roehm NW, Carbone A, Kushnir E, Taylor BA, Riblet RJ, Marrack P, Kappler JW
J Immunol. 1985
PubMed ID: 2410514
Sequence and evolution of the human T-cell antigen receptor beta-chain genes.
Tunnacliffe A, Kefford R, Milstein C, Forster A, Rabbitts TH
Proc Natl Acad Sci U S A. 1985
PubMed ID: 3860845
A large deletion within the T-cell receptor beta-chain gene complex in New Zealand white mice.
Kotzin BL, Barr VL, Palmer E
Science. 1985
PubMed ID: 2990044
Location of gene for beta subunit of human T-cell receptor at band 7q35, a region prone to rearrangements in T cells.
Isobe M, Erikson J, Emanuel BS, Nowell PC, Croce CM
Science. 1985
PubMed ID: 3983641
Genetic markers of the antigen-specific T cell receptor locus.
Epstein R, Roehm N, Marrack P, Kappler J, Davis M, Hedrick S, Cohn M
J Exp Med. 1985
PubMed ID: 2580936
Ontogeny of the T-cell antigen receptor within the thymus.
Snodgrass HR, Kisielow P, Kiefer M, Steinmetz M, von Boehmer H
Nature. 1985
PubMed ID: 3871511
T cell antigen receptors and the immunoglobulin supergene family.
Hood L, Kronenberg M, Hunkapiller T
Cell. 1985
PubMed ID: 3917857
Localization of CT beta and C kappa on mouse chromosome 6.
D'Hoostelaere LA, Jouvin-Marche E, Huppi K
Immunogenetics. 1985
PubMed ID: 2995250
Complexity of human T-cell antigen receptor beta-chain constant- and variable-region genes.
Sims JE, Tunnacliffe A, Smith WJ, Rabbitts TH
Nature. 1984
PubMed ID: 6334238
Sequence and expression of transcripts of the human T-cell receptor beta-chain genes.
Yoshikai Y, Anatoniou D, Clark SP, Yanagi Y, Sangster R, Van den Elsen P, Terhorst C, Mak TW
Nature. 1984
PubMed ID: 6334237
Structure, expression and divergence of T-cell receptor beta-chain variable regions.
Patten P, Yokota T, Rothbard J, Chien Y, Arai K, Davis MM
Nature. 1984
PubMed ID: 6092964
Murine T cell receptor beta chain is encoded on chromosome 6.
Lee NE, D'Eustachio P, Pravtcheva D, Ruddle FH, Hedrick SM, Davis MM
J Exp Med. 1984
PubMed ID: 6206194
Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes.
Gascoigne NR, Chien Y, Becker DM, Kavaler J, Davis MM
Nature. 1984
PubMed ID: 6336329
Mouse T cell antigen receptor: structure and organization of constant and joining gene segments encoding the beta polypeptide.
Malissen M, Minard K, Mjolsness S, Kronenberg M, Goverman J, Hunkapiller T, Prystowsky MB, Yoshikai Y, Fitch F, Mak TW
Cell. 1984
PubMed ID: 6611207
The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans.
Caccia N, Kronenberg M, Saxe D, Haars R, Bruns GA, Goverman J, Malissen M, Willard H, Yoshikai Y, Simon M
Cell. 1984
PubMed ID: 6331676
Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins.
Hedrick SM, Nielsen EA, Kavaler J, Cohen DI, Davis MM
Nature. 1984
PubMed ID: 6546606
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins.
Hedrick SM, Cohen DI, Nielsen EA, Davis MM
Nature. 1984
PubMed ID: 6199676

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Entrez Gene	6957	21577	N/A
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Interactor	Interactor	Sources	Classification	Pubmed IDs
TRB@	CTCF	BioGRID	empirical	20404925
TRB@	NCOA6	BioGRID	empirical	10866662
TRB@	HLA-A	BioGRID	empirical	9586631
TRB@	TAF1B	BioGRID	empirical	12511607