TAPBP
| Gene Description: |
TAP binding protein (tapasin); TAP binding protein |
| Synonyms: |
TAPBP, TAPA, NGS17, D17Wsu91e, Tapbp, TPSN, TPN |
| Orthologs: |
Human TAPBP (protein-coding), Mouse Tapbp (protein-coding), Rat Tapbp (protein-coding)
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Sources
Sources
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Human-Mouse:
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HomoloGene, MGD, RGD, Inparanoid, OrthoMCL, KEGG
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Human-Rat:
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HomoloGene, MGD, RGD, KEGG
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Mouse-Rat:
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HomoloGene, MGD, RGD, KEGG
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Possible sources:
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HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG
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Regions of Interest Overlapping this feature from T1DBase
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Regions Overlapping this Feature:
Human: 1
Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Gene Overview from T1DBase
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Beta Cell Gene Atlas from T1DBase
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| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray
data generated with pancreatic beta cells and related cell lines and types. The
expression data comes from 131 array analyses derived from 28 experiments
(open details in a new window).
The basal (untreated cell) expression signal intensity values in each array
were converted to ranks within the experiments; the highest value was used for
genes represented by more than one probe. The rank values of genes in a given cell
type were averaged with other calculated values from experiments performed with the
same cell type. The rank transformation of the expression values enable comparison
of gene expression across different organisms and tissues.
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A red border around a cell indicates greater certainty in the data;
specifically, the gene has >0.95 probability of being expressed in the tissue.
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| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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Expression Legend
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Signal intensity values were converted to ranks within the experiments.
For genes represented by more than one probeset, we averaged the intensity
signals for each probeset across all tissues and chose the probeset with the
highest average value. The rank transformation of the expression values enables
comparison of gene expression across different organisms and tissues.
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Interactions Table for TAPBP:
The TAPBP interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
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Cross-Reference to Pathways and GO Terms
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View all
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KEGG Network: 1
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Biocarta: None available
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Reactome: None available
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NCI-Nature Pathway Interaction Database: None available
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Gene Ontology: 22
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NCI-Nature Pathway Interaction Database: None available
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Type 1 Diabetes Publications: 1
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Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes.
van der Slik AR, van den Eng I, Eerligh P, Doxiadis II, Koeleman BP, Roep BO, Giphart MJ
Tissue Antigens. 2007
PubMed ID: 17389020
Publications: 120
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Tapasin discriminates peptide-human leukocyte antigen-A*02:01 complexes formed with natural ligands.
Roder G, Geironson L, Rasmussen M, Harndahl M, Buus S, Paulsson K
J Biol Chem. 2011
PubMed ID: 21518758
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Human cytomegalovirus disrupts the major histocompatibility complex class I peptide-loading complex and inhibits tapasin gene transcription.
Halenius A, Hauka S, Dölken L, Stindt J, Reinhard H, Wiek C, Hanenberg H, Koszinowski UH, Momburg F, Hengel H
J Virol. 2011
PubMed ID: 21248040
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Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
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Identification of E2F1 as an important transcription factor for the regulation of tapasin expression.
Bukur J, Herrmann F, Handke D, Recktenwald C, Seliger B
J Biol Chem. 2010
PubMed ID: 20663889
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Downregulation of tapasin expression in primary human oral squamous cell carcinoma: association with clinical outcome.
Jiang Q, Pan HY, Ye DX, Zhang P, Zhong LP, Zhang ZY
Tumour Biol. 2010
PubMed ID: 20532727
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Mechanisms of function of tapasin, a critical major histocompatibility complex class I assembly factor.
Rizvi SM, Raghavan M
Traffic. 2010
PubMed ID: 20070606
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Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange.
Praveen PV, Yaneva R, Kalbacher H, Springer S
Eur J Immunol. 2010
PubMed ID: 20017190
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Absence of tapasin alters immunodominance against a lymphocytic choriomeningitis virus polytope.
Boulanger DS, Oliveira R, Ayers L, Prior SH, James E, Williams AP, Elliott T
J Immunol. 2010
PubMed ID: 19949070
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Effect of a tapasin mutant on the assembly of the mouse MHC class I molecule H2-K(d).
Simone LC, Wang X, Tuli A, Solheim JC
Immunol Cell Biol. 2010
PubMed ID: 19687800
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Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP.
Iijima M, Tomita M, Morozumi S, Kawagashira Y, Nakamura T, Koike H, Katsuno M, Hattori N, Tanaka F, Yamamoto M, Sobue G
Neurology. 2009
PubMed ID: 19776380
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High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
PLoS Genet. 2009
PubMed ID: 19851445
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The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I.
Roder G, Geironson L, Darabi A, Harndahl M, Schafer-Nielsen C, Skjødt K, Buus S, Paulsson K
Eur J Immunol. 2009
PubMed ID: 19728311
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Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation.
Vigneron N, Peaper DR, Leonhardt RM, Cresswell P
Eur J Immunol. 2009
PubMed ID: 19701894
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Comparative analysis of the impact of a free cysteine in tapasin on the maturation and surface expression of murine MHC class I allotypes.
Wang X, Simone LC, Tuli A, Solheim JC
Int J Immunogenet. 2009
PubMed ID: 19490214
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Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
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Transporter associated with antigen processing and the chaperone tapasin: are non-classical HLA genes keys to the pathogenesis of schizophrenia?
Fellerhoff B, Wank R
Med Hypotheses. 2009
PubMed ID: 19217216
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ERp57 does not require interactions with calnexin and calreticulin to promote assembly of class I histocompatibility molecules, and it enhances peptide loading independently of its redox activity.
Zhang Y, Kozlov G, Pocanschi CL, Brockmeier U, Ireland BS, Maattanen P, Howe C, Elliott T, Gehring K, Williams DB
J Biol Chem. 2009
PubMed ID: 19196713
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HLA-B27 polymorphism at position 116 critically influences the association with TAP/tapasin, intracellular trafficking and conformational homodimers formation.
Blanco-Gelaz MA, Suárez-Alvarez B, Díaz-Peña R, López-Larrea C
Mol Immunol. 2009
PubMed ID: 19167761
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Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
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Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.
Dong G, Wearsch PA, Peaper DR, Cresswell P, Reinisch KM
Immunity. 2009
PubMed ID: 19119025
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Influence of the tapasin C terminus on the assembly of MHC class I allotypes.
Simone LC, Wang X, Tuli A, McIlhaney MM, Solheim JC
Immunogenetics. 2009
PubMed ID: 18958466
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
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CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kappaB and of NF-kappaB-mediated de novo synthesis of IRF-1.
Moschonas A, Kouraki M, Knox PG, Thymiakou E, Kardassis D, Eliopoulos AG
Mol Cell Biol. 2008
PubMed ID: 18694960
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The role of tapasin in MHC class I protein trafficking in embryos and T cells.
Lampton PW, Goldstein CY, Warner CM
J Reprod Immunol. 2008
PubMed ID: 18061684
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The convergent roles of tapasin and HLA-DM in antigen presentation.
Sadegh-Nasseri S, Chen M, Narayan K, Bouvier M
Trends Immunol. 2008
PubMed ID: 18261958
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Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer.
Deshpande A, Wheeler CM, Hunt WC, Peyton CL, White PS, Valdez YE, Nolan JP
J Infect Dis. 2008
PubMed ID: 18248301
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Tapasin shapes immunodominance hierarchies according to the kinetic stability of peptide-MHC class I complexes.
Thirdborough SM, Roddick JS, Radcliffe JN, Howarth M, Stevenson FK, Elliott T
Eur J Immunol. 2008
PubMed ID: 18196518
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Formation of a major histocompatibility complex class I tapasin disulfide indicates a change in spatial organization of the peptide-loading complex during assembly.
Chambers JE, Jessop CE, Bulleid NJ
J Biol Chem. 2008
PubMed ID: 18039656
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Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.
Imami K, Sugiyama N, Kyono Y, Tomita M, Ishihama Y
Anal Sci. 2008
PubMed ID: 18187866
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Molecular architecture of the TAP-associated MHC class I peptide-loading complex.
Rufer E, Leonhardt RM, Knittler MR
J Immunol. 2007
PubMed ID: 17947644
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An extra molecule in addition to human tapasin is required for surface expression of beta2m linked HLA-B4402 on murine cell.
Flutter B, Fu HM, Wedderburn L, Gao B
Mol Immunol. 2007
PubMed ID: 17498802
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A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins.
Tiwari N, Garbi N, Reinheckel T, Moldenhauer G, Hämmerling GJ, Momburg F
J Immunol. 2007
PubMed ID: 17548631
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Multiple residues in the transmembrane helix and connecting peptide of mouse tapasin stabilize the transporter associated with the antigen-processing TAP2 subunit.
Papadopoulos M, Momburg F
J Biol Chem. 2007
PubMed ID: 17244610
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hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Lamesch P, Li N, Milstein S, Fan C, Hao T, Szabo G, Hu Z, Venkatesan K, Bethel G, Martin P, Rogers J, Lawlor S, McLaren S, Dricot A, Borick H, Cusick ME, Vandenhaute J, Dunham I, Hill DE, Vidal M
Genomics. 2007
PubMed ID: 17207965
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Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.
Park B, Lee S, Kim E, Cho K, Riddell SR, Cho S, Ahn K
Cell. 2006
PubMed ID: 17055437
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The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding.
Koch J, Guntrum R, Tampé R
FEBS Lett. 2006
PubMed ID: 16828748
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In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules.
Yan J, Parekh VV, Mendez-Fernandez Y, Olivares-Villagómez D, Dragovic S, Hill T, Roopenian DC, Joyce S, Van Kaer L
J Exp Med. 2006
PubMed ID: 16505142
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Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
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Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57.
Garbi N, Tanaka S, Momburg F, Hämmerling GJ
Nat Immunol. 2006
PubMed ID: 16311600
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Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors.
Facoetti A, Nano R, Zelini P, Morbini P, Benericetti E, Ceroni M, Campoli M, Ferrone S
Clin Cancer Res. 2005
PubMed ID: 16322289
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Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading complex.
Peaper DR, Wearsch PA, Cresswell P
EMBO J. 2005
PubMed ID: 16193070
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Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
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Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway.
Chen M, Tabaczewski P, Truscott SM, Van Kaer L, Stroynowski I
J Immunol. 2005
PubMed ID: 16002705
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Qualitative and quantitative differences in peptides bound to HLA-B27 in the presence of mouse versus human tapasin define a role for tapasin as a size-dependent peptide editor.
Sesma L, Galocha B, Vázquez M, Purcell AW, Marcilla M, McCluskey J, López de Castro JA
J Immunol. 2005
PubMed ID: 15944288
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Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation.
Robbins SH, Tessmer MS, Van Kaer L, Brossay L
Eur J Immunol. 2005
PubMed ID: 15719366
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Involvement of the chaperone tapasin in HLA-B44 allelic losses in colorectal tumors.
Cabrera CM, López-Nevot MA, Jiménez P, Garrido F
Int J Cancer. 2005
PubMed ID: 15455354
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A charged amino acid residue in the transmembrane/cytoplasmic region of tapasin influences MHC class I assembly and maturation.
Petersen JL, Hickman-Miller HD, McIlhaney MM, Vargas SE, Purcell AW, Hildebrand WH, Solheim JC
J Immunol. 2005
PubMed ID: 15634919
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Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study.
Bukulmez H, Fife M, Tsoras M, Thompson SD, Twine NA, Woo P, Olson JM, Elston RC, Glass DN, Colbert RA
Arthritis Res Ther. 2005
PubMed ID: 15743475
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Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
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Differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to Qa-1b-restricted CTLs.
Li L, Sullivan BA, Aldrich CJ, Soloski MJ, Forman J, Grandea AG, Jensen PE, Van Kaer L
J Immunol. 2004
PubMed ID: 15356116
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Genomic analysis of mouse retinal development.
Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
PLoS Biol. 2004
PubMed ID: 15226823
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Tapasin enhances MHC class I peptide presentation according to peptide half-life.
Howarth M, Williams A, Tolstrup AB, Elliott T
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15286279
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The MHC-encoded class I molecule, H-2Kk, demonstrates distinct requirements of assembly factors for cell surface expression: roles of TAP, Tapasin and beta2-microglobulin.
Prasanna SJ, Nandi D
Mol Immunol. 2004
PubMed ID: 15302165
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Tapasin decreases immune responsiveness to a model tumor antigen.
Turnquist HR, Kohlgraf KG, McIlhaney MM, Mosley RL, Hollingsworth MA, Solheim JC
J Clin Immunol. 2004
PubMed ID: 15163903
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Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.
Abe K, Yuzuriha M, Sugimoto M, Ko MS, Brathwaite M, Waeltz P, Nagaraja R
Mamm Genome. 2004
PubMed ID: 15112104
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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
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The Ig-like domain of tapasin influences intermolecular interactions.
Turnquist HR, Petersen JL, Vargas SE, McIlhaney MM, Bedows E, Mayer WE, Grandea AG, Van Kaer L, Solheim JC
J Immunol. 2004
PubMed ID: 14978101
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Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA.
Gao B, Williams A, Sewell A, Elliott T
Genes Immun. 2004
PubMed ID: 14668790
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Tapasin is a facilitator, not an editor, of class I MHC peptide binding.
Zarling AL, Luckey CJ, Marto JA, White FM, Brame CJ, Evans AM, Lehner PJ, Cresswell P, Shabanowitz J, Hunt DF, Engelhard VH
J Immunol. 2003
PubMed ID: 14607930
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The DNA sequence and analysis of human chromosome 6.
Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S
Nature. 2003
PubMed ID: 14574404
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Association of tapasin and HLA class I antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients.
Ogino T, Bandoh N, Hayashi T, Miyokawa N, Harabuchi Y, Ferrone S
Clin Cancer Res. 2003
PubMed ID: 14519625
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Characterization of the ERp57-Tapasin complex by rapid cellular acidification and thiol modification.
Antoniou AN, Powis SJ
Antioxid Redox Signal. 2003
PubMed ID: 13678524
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Chaperones and folding of MHC class I molecules in the endoplasmic reticulum.
Paulsson K, Wang P
Biochim Biophys Acta. 2003
PubMed ID: 12788224
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Tapasin-/- and TAP1-/- macrophages are deficient in vacuolar alternate class I MHC (MHC-I) processing due to decreased MHC-I stability at phagolysosomal pH.
Chefalo PJ, Grandea AG, Van Kaer L, Harding CV
J Immunol. 2003
PubMed ID: 12794107
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Downregulation of tapasin expression in progressive human malignant melanoma.
Dissemond J, Kothen T, Mörs J, Weimann TK, Lindeke A, Goos M, Wagner SN
Arch Dermatol Res. 2003
PubMed ID: 12682852
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An essential function of tapasin in quality control of HLA-G molecules.
Park B, Ahn K
J Biol Chem. 2003
PubMed ID: 12582157
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Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells.
Vertegaal AC, Kuiperij HB, Houweling A, Verlaan M, van der Eb AJ, Zantema A
J Biol Chem. 2003
PubMed ID: 12407112
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A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.
Garbi N, Tiwari N, Momburg F, Hämmerling GJ
Eur J Immunol. 2003
PubMed ID: 12594855
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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A characterization of the lumenal region of human tapasin reveals the presence of two structural domains.
Chen M, Stafford WF, Diedrich G, Khan A, Bouvier M
Biochemistry. 2002
PubMed ID: 12463753
-
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
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Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes.
Raghuraman G, Lapinski PE, Raghavan M
J Biol Chem. 2002
PubMed ID: 12213826
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Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum.
Momburg F, Tan P
Mol Immunol. 2002
PubMed ID: 12200052
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Regulation of the expression of mouse TAP-associated glycoprotein (tapasin) by cytokines.
Abarca-Heidemann K, Friederichs S, Klamp T, Boehm U, Guethlein LA, Ortmann B
Immunol Lett. 2002
PubMed ID: 12095710
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Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.
Lemon WJ, Bernert H, Sun H, Wang Y, You M
J Med Genet. 2002
PubMed ID: 12205107
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A subject with a novel type I bare lymphocyte syndrome has tapasin deficiency due to deletion of 4 exons by Alu-mediated recombination.
Yabe T, Kawamura S, Sato M, Kashiwase K, Tanaka H, Ishikawa Y, Asao Y, Oyama J, Tsuruta K, Tokunaga K, Tadokoro K, Juji T
Blood. 2002
PubMed ID: 12149238
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Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits.
Antoniou AN, Ford S, Pilley ES, Blake N, Powis SJ
Immunology. 2002
PubMed ID: 12047747
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Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum.
Paulsson KM, Kleijmeer MJ, Griffith J, Jevon M, Chen S, Anderson PO, Sjogren HO, Li S, Wang P
J Biol Chem. 2002
PubMed ID: 11884415
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Optimization of the MHC class I peptide cargo is dependent on tapasin.
Williams AP, Peh CA, Purcell AW, McCluskey J, Elliott T
Immunity. 2002
PubMed ID: 11970875
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Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading.
Tan P, Kropshofer H, Mandelboim O, Bulbuc N, Hämmerling GJ, Momburg F
J Immunol. 2002
PubMed ID: 11823531
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Assembly and cell surface expression of TAP-independent, chloroquine-sensitive and interferon-gamma-inducible class I MHC complexes in transformed fibroblast cell lines are regulated by tapasin.
Fromm SV, Duady-Ben Yaakov S, Schechter C, Ehrlich R
Cell Immunol. 2002
PubMed ID: 12202157
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The interface between tapasin and MHC class I: identification of amino acid residues in both proteins that influence their interaction.
Turnquist HR, Vargas SE, Schenk EL, McIlhaney MM, Reber AJ, Solheim JC
Immunol Res. 2002
PubMed ID: 12018464
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Calreticulin binds to the alpha1 domain of MHC class I independently of tapasin.
Turnquist HR, Vargas SE, McIlhaney MM, Li S, Wang P, Solheim JC
Tissue Antigens. 2002
PubMed ID: 11972874
-
Is tapasin a modified Mhc class I molecule?
Mayer WE, Klein J
Immunogenetics. 2001
PubMed ID: 11862402
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Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Piao Y, Ko NT, Lim MK, Ko MS
Genome Res. 2001
PubMed ID: 11544199
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Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers.
Lybarger L, Yu YY, Chun T, Wang CR, Grandea AG, Van Kaer L, Hansen TH
J Immunol. 2001
PubMed ID: 11489993
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Functional roles of TAP and tapasin in the assembly of M3-N-formylated peptide complexes.
Chun T, Grandea AG, Lybarger L, Forman J, Van Kaer L, Wang CR
J Immunol. 2001
PubMed ID: 11466371
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Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
-
Rat tapasin: cDNA cloning and identification as a component of the class I MHC assembly complex.
Deverson EV, Powis SJ, Morrice NA, Herberg JA, Trowsdale J, Butcher GW
Genes Immun. 2001
PubMed ID: 11294569
-
Role of tapasin in MHC class I antigen presentation in vivo.
Garbi N, Tan P, Momburg F, Hämmerling GJ
Adv Exp Med Biol. 2001
PubMed ID: 11774611
-
Identification of novel Tapasin polymorphisms and linkage disequilibrium to MHC class I alleles.
Williams AP, Bevan S, Bunce M, Houlston R, Welsh KI, Elliott T
Immunogenetics. 2000
PubMed ID: 11132161
-
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
-
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
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Impaired immune responses and altered peptide repertoire in tapasin-deficient mice.
Garbi N, Tan P, Diehl AD, Chambers BJ, Ljunggren HG, Momburg F, Hämmerling GJ
Nat Immunol. 2000
PubMed ID: 10973281
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Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice.
Grandea AG, Golovina TN, Hamilton SE, Sriram V, Spies T, Brutkiewicz RR, Harty JT, Eisenlohr LC, Van Kaer L
Immunity. 2000
PubMed ID: 10981964
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Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
-
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
-
Tapasin is required for efficient peptide binding to transporter associated with antigen processing.
Li S, Paulsson KM, Chen S, Sjögren HO, Wang P
J Biol Chem. 2000
PubMed ID: 10636848
-
Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules.
Knittler MR, Alberts P, Deverson EV, Howard JC
Curr Biol. 1999
PubMed ID: 10508608
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The N-terminal region of tapasin is required to stabilize the MHC class I loading complex.
Bangia N, Lehner PJ, Hughes EA, Surman M, Cresswell P
Eur J Immunol. 1999
PubMed ID: 10382748
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Peptide-bound major histocompatibility complex class I molecules associate with tapasin before dissociation from transporter associated with antigen processing.
Li S, Paulsson KM, Sjögren HO, Wang P
J Biol Chem. 1999
PubMed ID: 10085102
-
Granulocyte-macrophage colony-stimulating factor modulates tapasin expression in human neutrophils.
El Ouakfaoui S, Heitz D, Paquin R, Beaulieu AD
J Leukoc Biol. 1999
PubMed ID: 10088603
-
Genes regulating MHC class I processing of antigen.
van Endert PM
Curr Opin Immunol. 1999
PubMed ID: 10047538
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
-
Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Ko MS, Threat TA, Wang X, Horton JH, Cui Y, Wang X, Pryor E, Paris J, Wells-Smith J, Kitchen JR, Rowe LB, Eppig J, Satoh T, Brant L, Fujiwara H, Yotsumoto S, Nakashima H
Hum Mol Genet. 1998
PubMed ID: 9811942
-
Polymorphism of TAPASIN and its linkage disequilibria with HLA class II genes in the Japanese population.
Furukawa H, Kashiwase K, Yabe T, Ishikawa Y, Akaza T, Tadokoro K, Tohma S, Inoue T, Tokunaga K, Yamamoto K, Juji T
Tissue Antigens. 1998
PubMed ID: 9802609
-
Sequence, linkage to H2-K, and function of mouse tapasin in MHC class I assembly.
Grandea AG, Comber PG, Wenderfer SE, Schoenhals G, Früh K, Monaco JJ, Spies T
Immunogenetics. 1998
PubMed ID: 9716645
-
ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.
Lindquist JA, Jensen ON, Mann M, Hämmerling GJ
EMBO J. 1998
PubMed ID: 9545232
-
TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.
Herberg JA, Beck S, Trowsdale J
J Mol Biol. 1998
PubMed ID: 9545376
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Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC.
Herberg JA, Sgouros J, Jones T, Copeman J, Humphray SJ, Sheer D, Cresswell P, Beck S, Trowsdale J
Eur J Immunol. 1998
PubMed ID: 9521053
-
A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.
Ortmann B, Copeman J, Lehner PJ, Sadasivan B, Herberg JA, Grandea AG, Riddell SR, Tampé R, Spies T, Trowsdale J, Cresswell P
Science. 1997
PubMed ID: 9271576
-
Cloning and functional characterization of a subunit of the transporter associated with antigen processing.
Li S, Sjögren HO, Hellman U, Pettersson RF, Wang P
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9238042
-
Large-scale concatenation cDNA sequencing.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA
Genome Res. 1997
PubMed ID: 9110174
-
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
-
Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.
Sadasivan B, Lehner PJ, Ortmann B, Spies T, Cresswell P
Immunity. 1996
PubMed ID: 8769474
-
Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP.
Lewis JW, Neisig A, Neefjes J, Elliott T
Curr Biol. 1996
PubMed ID: 8805302
-
A "double adaptor" method for improved shotgun library construction.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA
Anal Biochem. 1996
PubMed ID: 8619474
Model Organism Phenotype Links
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This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network
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Relevant resources:
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