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TAP1

Gene Description:   transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Synonyms:   Ham1, ABC17, MGC124549, PSF1, FLJ26666, ABCB2, TAP1N, Abcb2, APT1, D6S114E, MTP1, RING4, Tap-1, FLJ41500, TAP1, PSF-1, Cim, TAP, Y3, TAP1*0102N, Ham-1, Tap1 Orthologs:   Human TAP1 (protein-coding), Mouse Tap1 (protein-coding), Rat Tap1 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, KEGG Human-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL, KEGG Mouse-Rat: HomoloGene, MGD, RGD, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
MHC	Human	chr6:29910021..33498585	3.59	688

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd1	Mouse	chr17:34132973..35404440	1.27	98	6 no lod score

(Human) GRCh37 - chr6:32812986..32821755 (8.77 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr17:34324498..34334170 (9.67 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr20:4790363..4800997 (10.63 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for TAP1: The TAP1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs TAP1   NUPL2   MINT  empirical    TAP1   COPB1   BioGRID  empirical  11884415  TAP1   ESR1   HPRD  empirical  9774463  TAP1   COPG   BioGRID  empirical  11884415  TAP1   PDIA3   HPRD, IntAct, BioGRID  empirical  9545232  17055437  TAP1   HLA-A   BioGRID  empirical  11884415  TAP1   HLA-F   HPRD  empirical  11169396  TAP1   HLA-G   HPRD, BioGRID  empirical  9103419  TAP1   MDFI   HPRD, MINT, IntAct, BioGRID  empirical  16189514  TAP1   P4HB   IntAct  empirical  17055437  TAP1   B2M   IntAct  empirical  17055437  TAP1   PSMB5   HPRD  empirical  15488952  TAP1   PSMB8   HPRD, IntAct  empirical  15488952  TAP1   PSMB9   IntAct  empirical  15488952  TAP1   TAP2   HPRD, MINT, IntAct, BioGRID, Reactome  empirical  11381133  11133832  16828748  12213826  17055437  TAP1   TAPBP   HPRD, IntAct, BioGRID  empirical  12213826  16828748  17055437  11884415  TAP1   CALR   IntAct  empirical  17055437  TAP1   KRTAP4-12   HPRD, MINT, IntAct, BioGRID  empirical  16189514  TAP1   THOC5   MINT  empirical

View all

KEGG Network: 4   ABC transporters Human - 2010 Mouse - 2010 Rat - 2010 Antigen processing and presentation Human - 4612 Mouse - 4612 Rat - 4612 Phagosome Human - 4145 Mouse - 4145 Rat - 4145 Primary immunodeficiency Human - 5340 Mouse - 5340 Rat - 5340

Biocarta: 1   Antigen Processing and Presentation Human

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: 1   Direct p53 effectors

Gene Ontology: 35   Nucleotide binding GO:0000166 Positive regulation of T cell mediated cytotoxicity GO:0001916 Antigen processing and presentation of peptide antigen via MHC class I GO:0002474 Transporter activity GO:0005215 Protein binding GO:0005515 ATP binding GO:0005524 Mitochondrial inner membrane GO:0005743 Endoplasmic reticulum GO:0005783 Endoplasmic reticulum membrane GO:0005789 Microsome GO:0005792 Cytosol GO:0005829 Plasma membrane GO:0005886 Protein transport GO:0015031 Peptide transporter activity GO:0015197 Oligopeptide-transporting ATPase activity GO:0015421 Peptide transport GO:0015833 Integral to membrane GO:0016021 ATPase activity GO:0016887 Intracellular transport of viral proteins in host cell GO:0019060 Antigen processing and presentation of endogenous peptide antigen via MHC class I GO:0019885 Integral to endoplasmic reticulum membrane GO:0030176 Protection from natural killer cell mediated cytotoxicity GO:0042270 MHC class I protein binding GO:0042288 Peptide antigen binding GO:0042605 ATPase activity, coupled to transmembrane movement of substances GO:0042626 Protein homodimerization activity GO:0042803 TAP complex GO:0042825 ADP binding GO:0043531 Interspecies interaction between organisms GO:0044419 Cytosol to ER transport GO:0046967 TAP1 binding GO:0046978 TAP2 binding GO:0046979 Tapasin binding GO:0046980 Protein heterodimerization activity GO:0046982 Transmembrane transport GO:0055085

	KEGG Network: 4 ABC transporters Human - 2010 Mouse - 2010 Rat - 2010 Antigen processing and presentation Human - 4612 Mouse - 4612 Rat - 4612 Phagosome Human - 4145 Mouse - 4145 Rat - 4145 Primary immunodeficiency Human - 5340 Mouse - 5340 Rat - 5340
	Biocarta: 1 Antigen Processing and Presentation Human
	Reactome: None available
	NCI-Nature Pathway Interaction Database: 1 Direct p53 effectors
	Gene Ontology: 35 Nucleotide binding GO:0000166 Positive regulation of T cell mediated cytotoxicity GO:0001916 Antigen processing and presentation of peptide antigen via MHC class I GO:0002474 Transporter activity GO:0005215 Protein binding GO:0005515 ATP binding GO:0005524 Mitochondrial inner membrane GO:0005743 Endoplasmic reticulum GO:0005783 Endoplasmic reticulum membrane GO:0005789 Microsome GO:0005792 Cytosol GO:0005829 Plasma membrane GO:0005886 Protein transport GO:0015031 Peptide transporter activity GO:0015197 Oligopeptide-transporting ATPase activity GO:0015421 Peptide transport GO:0015833 Integral to membrane GO:0016021 ATPase activity GO:0016887 Intracellular transport of viral proteins in host cell GO:0019060 Antigen processing and presentation of endogenous peptide antigen via MHC class I GO:0019885 Integral to endoplasmic reticulum membrane GO:0030176 Protection from natural killer cell mediated cytotoxicity GO:0042270 MHC class I protein binding GO:0042288 Peptide antigen binding GO:0042605 ATPase activity, coupled to transmembrane movement of substances GO:0042626 Protein homodimerization activity GO:0042803 TAP complex GO:0042825 ADP binding GO:0043531 Interspecies interaction between organisms GO:0044419 Cytosol to ER transport GO:0046967 TAP1 binding GO:0046978 TAP2 binding GO:0046979 Tapasin binding GO:0046980 Protein heterodimerization activity GO:0046982 Transmembrane transport GO:0055085

Type 1 Diabetes Publications: 14

• Genetic susceptibility to type 1 diabetes in the intracellular pathway of antigen processing - a subject review and cross-study comparison.
  Sia C, Weinem M
  Rev Diabet Stud. 2005
  PubMed ID: 17491658
   
  
• Is TAP2*0102 allele involved in insulin-dependent diabetes mellitus (type 1) protection?
  Cesari M, Hoarau JJ, Caillens H, Robert C, Rouch C, Cadet F, Pabion M
  Hum Immunol. 2004
  PubMed ID: 15336779
   
  
• Polymorphisms of human TAP2 detected by denaturing gradient gel electrophoresis.
  Penfornis A, Yan G, Shi L, Faustman DL
  Hum Immunol. 2003
  PubMed ID: 12507827
   
  
• Cutting edge: TCR alpha beta+ CD8 alpha alpha+ T cells are found in intestinal intraepithelial lymphocytes of mice that lack classical MHC class I molecules.
  Gapin L, Cheroutre H, Kronenberg M
  J Immunol. 1999
  PubMed ID: 10510343
   
  
• Screening of the TAP1 gene by denaturing gradient gel electrophoresis in insulin-dependent diabetes mellitus: detection and comparison of new polymorphisms between patients and controls.
  Yan G, Shi L, Fu Y, Wang X, Schoenfeld D, Ma L, Penfornis A, Gebel H, Faustman DL
  Tissue Antigens. 1997
  PubMed ID: 9458110
   
  
• Reduced expression of Tap1 and Lmp2 antigen-processing genes in the nonobese diabetic (NOD) mouse due to a mutation in their shared bidirectional promoter.
  Yan G, Fu Y, Faustman DL
  J Immunol. 1997
  PubMed ID: 9300732
   
  
• Evaluation of TAP1 polymorphisms with insulin dependent diabetes mellitus in Finnish diabetic patients. The Childhood Diabetes in Finland (DiMe) Study Group.
  Ma L, Penfornis A, Wang X, Schoenfeld D, Tuomilehto-Wolf E, Metcalfe K, Hitman G, Faustman D
  Hum Immunol. 1997
  PubMed ID: 9129974
   
  
• Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.
  Ikegami H, Makino S, Yamato E, Kawaguchi Y, Ueda H, Sakamoto T, Takekawa K, Ogihara T
  J Clin Invest. 1995
  PubMed ID: 7560085
   
  
• Levels of Tap-1 and Tap-2 mRNA and expression of Kd and Db on splenic lymphocytes are normal in NOD mice.
  Pearce RB, Trigler L, Svaasand EK, Chen HM, Peterson CM
  Diabetes. 1995
  PubMed ID: 7729618
   
  
• TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.
  Jackson DG, Capra JD
  Proc Natl Acad Sci U S A. 1993
  PubMed ID: 8248212
   
  
• Genomic organization of the mouse Lmp-2 gene and characteristic structure of its promoter.
  Kishi F, Suminami Y, Monaco JJ
  Gene. 1993
  PubMed ID: 7901128
   
  
• Expression of intra-MHC transporter (Ham) genes and class I antigens in diabetes-susceptible NOD mice.
  Gaskins HR, Monaco JJ, Leiter EH
  Science. 1992
  PubMed ID: 1352067
   
  
• Allelic variants of the human putative peptide transporter involved in antigen processing.
  Colonna M, Bresnahan M, Bahram S, Strominger JL, Spies T
  Proc Natl Acad Sci U S A. 1992
  PubMed ID: 1570316
   
  
• TAP1 and TAP2 transporter genes and predisposition to insulin dependent diabetes mellitus.
  Caillat-Zucman S, Bertin E, Timsit J, Boitard C, Assan R, Bach JF
  C R Acad Sci III. 1992
  PubMed ID: 1300236
   
  

Publications: 381

• Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection.
  Murthy AK, Li W, Chaganty BK, Kamalakaran S, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP
  Infect Immun. 2011
  PubMed ID: 21536799
   
  
• Hydrophobicity as a driver of MHC class I antigen processing.
  Huang L, Kuhls MC, Eisenlohr LC
  EMBO J. 2011
  PubMed ID: 21378750
   
  
• MHCI negatively regulates synapse density during the establishment of cortical connections.
  Glynn MW, Elmer BM, Garay PA, Liu XB, Needleman LA, El-Sabeawy F, McAllister AK
  Nat Neurosci. 2011
  PubMed ID: 21358642
   
  
• Type I interferon supports primary CD8+ T-cell responses to peptide-pulsed dendritic cells in the absence of CD4+ T-cell help.
  Ontiveros F, Wilson EB, Livingstone AM
  Immunology. 2011
  PubMed ID: 21255009
   
  
• Deficiency of activated STAT1 in head and neck cancer cells mediates TAP1-dependent escape from cytotoxic T lymphocytes.
  Leibowitz MS, Andrade Filho PA, Ferrone S, Ferris RL
  Cancer Immunol Immunother. 2011
  PubMed ID: 21207025
   
  
• Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses.
  Verweij MC, Ressing ME, Knetsch W, Quinten E, Halenius A, van Bel N, Hengel H, Drijfhout JW, van Hall T, Wiertz EJ
  Mol Immunol. 2011
  PubMed ID: 21292324
   
  
• Association of defective HLA-I expression with antigen processing machinery and their association with clinicopathological characteristics in Kazak patients with esophageal cancer.
  Ayshamgul H, Ma H, Ilyar S, Zhang LW, Abulizi A
  Chin Med J (Engl). 2011
  PubMed ID: 21362330
   
  
• Conformation of peptides bound to the transporter associated with antigen processing (TAP).
  Herget M, Baldauf C, Schölz C, Parcej D, Wiesmüller KH, Tampé R, Abele R, Bordignon E
  Proc Natl Acad Sci U S A. 2011
  PubMed ID: 21205905
   
  
• Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice.
  Liu Y, Teige A, Mondoc E, Ibrahim S, Holmdahl R, Issazadeh-Navikas S
  J Clin Invest. 2011
  PubMed ID: 21157037
   
  
• Genome-wide association study identifies susceptibility loci for IgA nephropathy.
  Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, Wang W, Wang Z, Yasuno K, Gunel M, Mane S, Umlauf S, Tikhonova I, Beerman I, Savoldi S, Magistroni R, Ghiggeri GM, Bodria M, Lugani F, Ravani P, Ponticelli C, Allegri L, Boscutti G, Frasca G, Amore A, Peruzzi L, Coppo R, Izzi C, Viola BF, Prati E, Salvadori M, Mignani R, Gesualdo L, Bertinetto F, Mesiano P, Amoroso A, Scolari F, Chen N, Zhang H, Lifton RP
  Nat Genet. 2011
  PubMed ID: 21399633
   
  
• Initial characterization of the human central proteome.
  Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
  BMC Syst Biol. 2011
  PubMed ID: 21269460
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• CD8+ cells enhance resistance to pulmonary serotype 3 Streptococcus pneumoniae infection in mice.
  Weber SE, Tian H, Pirofski LA
  J Immunol. 2011
  PubMed ID: 21135172
   
  
• MHC class I modulates NMDA receptor function and AMPA receptor trafficking.
  Fourgeaud L, Davenport CM, Tyler CM, Cheng TT, Spencer MB, Boulanger LM
  Proc Natl Acad Sci U S A. 2010
  PubMed ID: 21135233
   
  
• The transporter associated with antigen processing (TAP) is active in a post-ER compartment.
  Ghanem E, Fritzsche S, Al-Balushi M, Hashem J, Ghuneim L, Thomer L, Kalbacher H, van Endert P, Wiertz E, Tampé R, Springer S
  J Cell Sci. 2010
  PubMed ID: 21098634
   
  
• Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes.
  van Luijn MM, Chamuleau ME, Ressing ME, Wiertz EJ, Ostrand-Rosenberg S, Souwer Y, Zevenbergen A, Ossenkoppele GJ, van de Loosdrecht AA, van Ham SM
  Cancer Immunol Immunother. 2010
  PubMed ID: 20820776
   
  
• A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
  Romero R, Friel LA, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, Bartlett J, Salisbury BA, Anant MK, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
  Am J Obstet Gynecol. 2010
  PubMed ID: 20673868
   
  
• Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
  Diabetes Care. 2010
  PubMed ID: 20628086
   
  
• Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.
  Murshid A, Gong J, Calderwood SK
  J Immunol. 2010
  PubMed ID: 20686127
   
  
• Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation.
  Ichiyanagi T, Imai T, Kajiwara C, Mizukami S, Nakai A, Nakayama T, Udono H
  J Immunol. 2010
  PubMed ID: 20668218
   
  
• No association of TAP and LMP genetic polymorphism in human brucellosis and its complications.
  Bravo MJ, Colmenero JD, Queipo-Ortuño MI, Martín J, Lavado R, Alonso A, Caballero A
  Hum Immunol. 2010
  PubMed ID: 20470844
   
  
• Genetic variation in the LMP/TAP gene and outcomes of hepatitis B virus infection in the Chinese population.
  Shi C, Qian YH, Su J, Luo SS, Gu J, You H, Cui Q, Lin YD, Dong MH, Yu RB
  Epidemiol Infect. 2010
  PubMed ID: 20525414
   
  
• Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
  Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
  Pediatr Pulmonol. 2010
  PubMed ID: 20503287
   
  
• TAP1 and TAP2 gene polymorphisms in childhood cystic echinococcosis.
  Kiper N, Gerçeker F, Utine E, Yalçin E, Pekcan S, Cobanoğlu N, Aslan A, Köse M, Doğru D, Ozçelik U, Ozgüç M
  Parasitol Int. 2010
  PubMed ID: 20193774
   
  
• The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation.
  Johnson KG, Kornfeld K
  Dev Biol. 2010
  PubMed ID: 20230813
   
  
• Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.
  Romero R, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Chaiworapongsa T, Pearce BD, Friel LA, Bartlett J, Anant MK, Salisbury BA, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
  Am J Obstet Gynecol. 2010
  PubMed ID: 20452482
   
  
• Impaired antigen processing and presentation machinery is associated with immunotolerant state in chronic hepatitis B virus infection.
  Sukriti S, Pati NT, Bose S, Hissar SS, Sarin SK
  J Clin Immunol. 2010
  PubMed ID: 20300807
   
  
• HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis.
  Bandoh N, Ogino T, Katayama A, Takahara M, Katada A, Hayashi T, Harabuchi Y
  Oncol Rep. 2010
  PubMed ID: 20204276
   
  
• Dimorphism of TAP-1 gene in Caucasian with juvenile myoclonic epilepsy and in Tunisian with idiopathic generalized epilepsies.
  Layouni S, Chouchane L, Malafosse A, Dogui M
  Int J Immunogenet. 2010
  PubMed ID: 20141545
   
  
• Adult neurogenesis is unaffected by a functional knock-out of MHC class I in mice.
  Laguna Goya R, Tyers P, Barker RA
  Neuroreport. 2010
  PubMed ID: 20147861
   
  
• [Transporter associated with antigen processing 1 637A/G gene polymorphisms and susceptibility to nasopharyngeal carcinoma in Han population in Yunnan Province, China]
  Sui J, Mo Q, Li XJ, Ma J, Ren YX, Gao W, Wang H, Yang J
  Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010
  PubMed ID: 20450707
   
  
• T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis.
  Cho JH, Kim HO, Surh CD, Sprent J
  Immunity. 2010
  PubMed ID: 20137986
   
  
• Down-regulation of HLA class I antigen in human papillomavirus type 16 E7 expressing HaCaT cells: correlate with TAP-1 expression.
  Li W, Deng XM, Wang CX, Zhang X, Zheng GX, Zhang J, Feng JB
  Int J Gynecol Cancer. 2010
  PubMed ID: 20134267
   
  
• BRD2 and TAP-1 genes and juvenile myoclonic epilepsy.
  Layouni S, Buresi C, Thomas P, Malafosse A, Dogui M
  Neurol Sci. 2010
  PubMed ID: 19953286
   
  
• Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cell-mediated cross-priming in vivo.
  Asano J, Tada H, Onai N, Sato T, Horie Y, Fujimoto Y, Fukase K, Suzuki A, Mak TW, Ohteki T
  J Immunol. 2010
  PubMed ID: 20008287
   
  
• Generation of functional NKT cells in vitro from embryonic stem cells bearing rearranged invariant Valpha14-Jalpha18 TCRalpha gene.
  Watarai H, Rybouchkin A, Hongo N, Nagata Y, Sakata S, Sekine E, Dashtsoodol N, Tashiro T, Fujii S, Shimizu K, Mori K, Masuda K, Kawamoto H, Koseki H, Taniguchi M
  Blood. 2010
  PubMed ID: 19897575
   
  
• Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
  Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
  PLoS One. 2010
  PubMed ID: 20877624
   
  
• Specific CD8 T cells in IgE-mediated allergy correlate with allergen dose and allergic phenotype.
  Aguilar-Pimentel JA, Alessandrini F, Huster KM, Jakob T, Schulz H, Behrendt H, Ring J, de Angelis MH, Busch DH, Mempel M, Ollert M
  Am J Respir Crit Care Med. 2010
  PubMed ID: 19815810
   
  
• Mouse strains with point mutations in TAP1 and TAP2.
  Theodoratos A, Whittle B, Enders A, Tscharke DC, Roots CM, Goodnow CC, Fahrer AM
  Immunol Cell Biol. 2010
  PubMed ID: 19721454
   
  
• Purification and reconstitution of the antigen transport complex TAP: a prerequisite for determination of peptide stoichiometry and ATP hydrolysis.
  Herget M, Kreissig N, Kolbe C, Schölz C, Tampé R, Abele R
  J Biol Chem. 2009
  PubMed ID: 19808685
   
  
• Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
  Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
  Am J Hum Genet. 2009
  PubMed ID: 19913121
   
  
• Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction.
  Thams S, Brodin P, Plantman S, Saxelin R, Kärre K, Cullheim S
  J Neurosci. 2009
  PubMed ID: 19864563
   
  
• Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation.
  Belizaire R, Unanue ER
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19805168
   
  
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
  PLoS Genet. 2009
  PubMed ID: 19851445
   
  
• Furin-processed antigens targeted to the secretory route elicit functional TAP1-/-CD8+ T lymphocytes in vivo.
  Medina F, Ramos M, Iborra S, de León P, Rodríguez-Castro M, Del Val M
  J Immunol. 2009
  PubMed ID: 19752221
   
  
• Dependence of the localization and function of the human cytomegalovirus protein US6 on the transporter associated with antigen processing.
  Dugan GE, Hewitt EW
  J Gen Virol. 2009
  PubMed ID: 19439551
   
  
• Maturation pathways of dendritic cells determine TAP1 and TAP2 levels and cross-presenting function.
  López-Albaitero A, Mailliard R, Hackman T, Andrade Filho PA, Wang X, Gooding W, Ferrone S, Kalinski P, Ferris RL
  J Immunother. 2009
  PubMed ID: 19609238
   
  
• [Distribution of tap1 and tap2 loci allelic and genotypic frequencies in Chinese Hans]
  Shen W, Shen T, Yin B, Zheng JW, Liu DZ, Feng ML
  Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009
  PubMed ID: 19549407
   
  
• Cutting edge: CD28 engagement releases antigen-activated invariant NKT cells from the inhibitory effects of PD-1.
  Wang J, Cheng L, Wondimu Z, Swain M, Santamaria P, Yang Y
  J Immunol. 2009
  PubMed ID: 19454657
   
  
• Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC.
  Ramos PS, Langefeld CD, Bera LA, Gaffney PM, Noble JA, Moser KL
  Genes Immun. 2009
  PubMed ID: 19387463
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis.
  Maksymowych WP, Inman RD, Gladman DD, Reeve JP, Pope A, Rahman P
  Arthritis Rheum. 2009
  PubMed ID: 19404951
   
  
• Analyses of associations with asthma in four asthma population samples from Canada and Australia.
  Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ
  Hum Genet. 2009
  PubMed ID: 19247692
   
  
• Transporter associated with antigen processing and the chaperone tapasin: are non-classical HLA genes keys to the pathogenesis of schizophrenia?
  Fellerhoff B, Wank R
  Med Hypotheses. 2009
  PubMed ID: 19217216
   
  
• Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma.
  Mehta AM, Jordanova ES, Corver WE, van Wezel T, Uh HW, Kenter GG, Jan Fleuren G
  Genes Chromosomes Cancer. 2009
  PubMed ID: 19202550
   
  
• In situ analysis of the antigen-processing machinery in acute myeloid leukaemic blasts by tissue microarray.
  Hoves S, Aigner M, Pfeiffer C, Laumer M, Obermann EC, Mackensen A
  Leukemia. 2009
  PubMed ID: 19148137
   
  
• Structural arrangement of the transmission interface in the antigen ABC transport complex TAP.
  Oancea G, O'Mara ML, Bennett WF, Tieleman DP, Abele R, Tampé R
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19297616
   
  
• TAP1 and TAP2 polymorphisms associated with ankylosing spondylitis in genetically homogenous Chinese Han population.
  Feng M, Yin B, Shen T, Ma Q, Liu L, Zheng J, Zhao Y, Qian K, Liu D
  Hum Immunol. 2009
  PubMed ID: 19480848
   
  
• No association of TAP1 and TAP2 genes polymorphism with risk of cervical cancer in north Indian population.
  Kordi Tamandani DM, Sobti RC, Shekari M, Husseini SA, Suri V
  J Assist Reprod Genet. 2009
  PubMed ID: 19263211
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
  Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R
  Pediatr Infect Dis J. 2009
  PubMed ID: 19258923
   
  
• Identification and characterization of stem cell-specific transcription of PSF1 in spermatogenesis.
  Han Y, Ueno M, Nagahama Y, Takakura N
  Biochem Biophys Res Commun. 2009
  PubMed ID: 19285009
   
  
• Stepwise development of MAIT cells in mouse and human.
  Martin E, Treiner E, Duban L, Guerri L, Laude H, Toly C, Premel V, Devys A, Moura IC, Tilloy F, Cherif S, Vera G, Latour S, Soudais C, Lantz O
  PLoS Biol. 2009
  PubMed ID: 19278296
   
  
• B-cell co-receptor CD72 is expressed on NK cells and inhibits IFN-gamma production but not cytotoxicity.
  Alcón VL, Luther C, Balce D, Takei F
  Eur J Immunol. 2009
  PubMed ID: 19197938
   
  
• Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation.
  Horst D, van Leeuwen D, Croft NP, Garstka MA, Hislop AD, Kremmer E, Rickinson AB, Wiertz EJ, Ressing ME
  J Immunol. 2009
  PubMed ID: 19201886
   
  
• Genetic variants in TAP are associated with high-grade cervical neoplasia.
  Einstein MH, Leanza S, Chiu LG, Schlecht NF, Goldberg GL, Steinberg BM, Burk RD
  Clin Cancer Res. 2009
  PubMed ID: 19188174
   
  
• Both alleles of PSF1 are required for maintenance of pool size of immature hematopoietic cells and acute bone marrow regeneration.
  Ueno M, Itoh M, Sugihara K, Asano M, Takakura N
  Blood. 2009
  PubMed ID: 18984863
   
  
• Dendritic cell cross-priming is essential for immune responses to Listeria monocytogenes.
  Reinicke AT, Omilusik KD, Basha G, Jefferies WA
  PLoS One. 2009
  PubMed ID: 19806187
   
  
• Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
  Saito A, Kawamoto M, Kamatani N
  J Hum Genet. 2009
  PubMed ID: 19343046
   
  
• Beta2-microglobulin-dependent bacterial clearance and survival during murine Klebsiella pneumoniae bacteremia.
  Cogen AL, Moore TA
  Infect Immun. 2009
  PubMed ID: 18981251
   
  
• The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex.
  Verweij MC, Koppers-Lalic D, Loch S, Klauschies F, de la Salle H, Quinten E, Lehner PJ, Mulder A, Knittler MR, Tampé R, Koch J, Ressing ME, Wiertz EJ
  J Immunol. 2008
  PubMed ID: 18802093
   
  
• CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kappaB and of NF-kappaB-mediated de novo synthesis of IRF-1.
  Moschonas A, Kouraki M, Knox PG, Thymiakou E, Kardassis D, Eliopoulos AG
  Mol Cell Biol. 2008
  PubMed ID: 18694960
   
  
• Colitis immunoregulation by CD8+ T cell requires T cell cytotoxicity and B cell peptide antigen presentation.
  McPherson M, Wei B, Turovskaya O, Fujiwara D, Brewer S, Braun J
  Am J Physiol Gastrointest Liver Physiol. 2008
  PubMed ID: 18617557
   
  
• Determination of TAP1 and TAP2 polymorphism in the Chinese Han population by real-time TaqMan polymerase chain reaction.
  Feng ML, Yin B, Shen T, Huang H, Zheng JW, Qian KC, Liu DZ
  Tissue Antigens. 2008
  PubMed ID: 18764808
   
  
• Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.
  Blanchard N, Gonzalez F, Schaeffer M, Joncker NT, Cheng T, Shastri AJ, Robey EA, Shastri N
  Nat Immunol. 2008
  PubMed ID: 18587399
   
  
• Restoration of the expression of transports associated with antigen processing in human malignant melanoma increases tumor-specific immunity.
  Tao J, Li Y, Liu YQ, Wang L, Yang J, Dong J, Wu Y, Shen GX, Tu YT
  J Invest Dermatol. 2008
  PubMed ID: 18385764
   
  
• Malaria-specific and nonspecific activation of CD8+ T cells during blood stage of Plasmodium berghei infection.
  Miyakoda M, Kimura D, Yuda M, Chinzei Y, Shibata Y, Honma K, Yui K
  J Immunol. 2008
  PubMed ID: 18606696
   
  
• A mitochondrial protein compendium elucidates complex I disease biology.
  Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, Mootha VK
  Cell. 2008
  PubMed ID: 18614015
   
  
• Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens.
  Lind EF, Ahonen CL, Wasiuk A, Kosaka Y, Becher B, Bennett KA, Noelle RJ
  J Immunol. 2008
  PubMed ID: 18566401
   
  
• IL-15 expands unconventional CD8alphaalphaNK1.1+ T cells but not Valpha14Jalpha18+ NKT cells.
  Terabe M, Tagaya Y, Zhu Q, Granger L, Roederer M, Waldmann TA, Berzofsky JA
  J Immunol. 2008
  PubMed ID: 18490727
   
  
• IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia.
  Boyman O, Ramsey C, Kim DM, Sprent J, Surh CD
  J Immunol. 2008
  PubMed ID: 18490726
   
  
• Polymorphisms of the TAP 1 and 2 gene may influence clinical outcome of primary dengue viral infection.
  Soundravally R, Hoti SL
  Scand J Immunol. 2008
  PubMed ID: 18433405
   
  
• The role of tapasin in MHC class I protein trafficking in embryos and T cells.
  Lampton PW, Goldstein CY, Warner CM
  J Reprod Immunol. 2008
  PubMed ID: 18061684
   
  
• Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota.
  Fujiwara D, Wei B, Presley LL, Brewer S, McPherson M, Lewinski MA, Borneman J, Braun J
  J Immunol. 2008
  PubMed ID: 18424703
   
  
• Transporter associated with antigen processing (TAP) 1 gene polymorphisms in patients with hypersensitivity pneumonitis.
  Aquino-Galvez A, Camarena A, Montaño M, Juarez A, Zamora AC, González-Avila G, Checa M, Sandoval-López G, Vargas-Alarcon G, Granados J, Pardo A, Zúñiga J, Selman M
  Exp Mol Pathol. 2008
  PubMed ID: 18342853
   
  
• Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6.
  Dugan GE, Hewitt EW
  J Virol. 2008
  PubMed ID: 18199642
   
  
• Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element.
  Skinner SJ, Deleault KM, Fecteau R, Brooks SA
  J Biol Chem. 2008
  PubMed ID: 18048358
   
  
• Disruption of the association of 73 kDa heat shock cognate protein with transporters associated with antigen processing (TAP) decreases TAP-dependent translocation of antigenic peptides into the endoplasmic reticulum.
  Kamiguchi K, Torigoe T, Fujiwara O, Ohshima S, Hirohashi Y, Sahara H, Hirai I, Kohgo Y, Sato N
  Microbiol Immunol. 2008
  PubMed ID: 18380807
   
  
• Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer.
  Deshpande A, Wheeler CM, Hunt WC, Peyton CL, White PS, Valdez YE, Nolan JP
  J Infect Dis. 2008
  PubMed ID: 18248301
   
  
• Development of all CD4 T lineages requires nuclear factor TOX.
  Aliahmad P, Kaye J
  J Exp Med. 2008
  PubMed ID: 18195075
   
  
• A detailed analysis of the murine TAP transporter substrate specificity.
  Burgevin A, Saveanu L, Kim Y, Barilleau E, Kotturi M, Sette A, van Endert P, Peters B
  PLoS One. 2008
  PubMed ID: 18545702
   
  
• Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression.
  Hayakawa Y, Watt SV, Takeda K, Smyth MJ
  J Leukoc Biol. 2008
  PubMed ID: 17940219
   
  
• Neonatal and adult microglia cross-present exogenous antigens.
  Beauvillain C, Donnou S, Jarry U, Scotet M, Gascan H, Delneste Y, Guermonprez P, Jeannin P, Couez D
  Glia. 2008
  PubMed ID: 17932942
   
  
• N-terminal trimer extension of nominal CD8 T cell epitopes is sufficient to promote cross-presentation to cognate CD8 T cells in vivo.
  Wei CH, Sherman LA
  J Immunol. 2007
  PubMed ID: 18056372
   
  
• Significance of Transporter Associated with Antigen Processing 2 (TAP2) Gene Polymorphisms in Susceptibility to Dengue Viral Infection.
  Soundravally R, Hoti SL
  J Clin Immunol. 2007
  PubMed ID: 18071882
   
  
• Immunopathogenesis of dengue hemorrhagic fever and shock syndrome: role of TAP and HPA gene polymorphism.
  Soundravally R, Hoti SL
  Hum Immunol. 2007
  PubMed ID: 18191725
   
  
• Molecular architecture of the TAP-associated MHC class I peptide-loading complex.
  Rufer E, Leonhardt RM, Knittler MR
  J Immunol. 2007
  PubMed ID: 17947644
   
  
• Epigenetic control of the immune escape mechanisms in malignant carcinomas.
  Setiadi AF, David MD, Seipp RP, Hartikainen JA, Gopaul R, Jefferies WA
  Mol Cell Biol. 2007
  PubMed ID: 17875943
   
  
• TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production.
  Goldszmid RS, Bafica A, Jankovic D, Feng CG, Caspar P, Winkler-Pickett R, Trinchieri G, Sher A
  J Exp Med. 2007
  PubMed ID: 17923502
   
  
• Neutrophils efficiently cross-prime naive T cells in vivo.
  Beauvillain C, Delneste Y, Scotet M, Peres A, Gascan H, Guermonprez P, Barnaba V, Jeannin P
  Blood. 2007
  PubMed ID: 17562875
   
  
• TAP1 and TAP2 gene polymorphisms in Korean patients with allergic rhinitis.
  Kim KR, Cho SH, Choi SJ, Jeong JH, Lee SH, Park CW, Tae K
  J Korean Med Sci. 2007
  PubMed ID: 17982230
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
  Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B
  J Infect Dis. 2007
  PubMed ID: 17703412
   
  
• Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype.
  Krämer U, Illig T, Grune T, Krutmann J, Esser C
  Genes Immun. 2007
  PubMed ID: 17581627
   
  
• Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis.
  Ismail N, Crossley EC, Stevenson HL, Walker DH
  Infect Immun. 2007
  PubMed ID: 17562770
   
  
• Genetic polymorphisms of LMP/TAP gene and hepatitis B virus infection risk in the Chinese population.
  Xu C, Qi S, Gao L, Cui H, Liu M, Yang H, Li K, Cao B
  J Clin Immunol. 2007
  PubMed ID: 17525827
   
  
• An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.
  Cho JH, Boyman O, Kim HO, Hahm B, Rubinstein MP, Ramsey C, Kim DM, Surh CD, Sprent J
  J Exp Med. 2007
  PubMed ID: 17664294
   
  
• Association study between hypertension and A/G polymorphism at codon 637 of the transporter associated with antigen processing 1 gene.
  Shen C, Guo Z, Wu M, Hu X, Yang G, Yu R, Shen H, Xu Y, Yao C
  Hypertens Res. 2007
  PubMed ID: 17917315
   
  
• Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells.
  Khan S, Bijker MS, Weterings JJ, Tanke HJ, Adema GJ, van Hall T, Drijfhout JW, Melief CJ, Overkleeft HS, van der Marel GA, Filippov DV, van der Burg SH, Ossendorp F
  J Biol Chem. 2007
  PubMed ID: 17462991
   
  
• A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins.
  Tiwari N, Garbi N, Reinheckel T, Moldenhauer G, Hämmerling GJ, Momburg F
  J Immunol. 2007
  PubMed ID: 17548631
   
  
• Systemic CD8 T-cell memory response to a Salmonella pathogenicity island 2 effector is restricted to Salmonella enterica encountered in the gastrointestinal mucosa.
  Jones-Carson J, McCollister BD, Clambey ET, Vázquez-Torres A
  Infect Immun. 2007
  PubMed ID: 17403871
   
  
• Expression and genetic analysis of transporter associated with antigen processing in cervical carcinoma.
  Vermeulen CF, Jordanova ES, ter Haar NT, Kolkman-Uljee SM, de Miranda NF, Ferrone S, Peters AA, Fleuren GJ
  Gynecol Oncol. 2007
  PubMed ID: 17382375
   
  
• Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1.
  Plewnia G, Schulze K, Hunte C, Tampé R, Koch J
  J Mol Biol. 2007
  PubMed ID: 17418234
   
  
• TCR beta chain that forms peptide-independent alloreactive TCR transfers reduced reactivity with irrelevant peptide/MHC complex.
  Santori FR, Popmihajlov Z, Badovinac VP, Smith C, Radoja S, Harty JT, Vukmanović S
  J Immunol. 2007
  PubMed ID: 17475836
   
  
• TAP1 gene polymorphisms and nasopharyngeal carcinoma risk in a Tunisian population.
  Hassen E, Farhat K, Gabbouj S, Jalbout M, Bouaouina N, Chouchane L
  Cancer Genet Cytogenet. 2007
  PubMed ID: 17498556
   
  
• Regulation of CNS synapses by neuronal MHC class I.
  Goddard CA, Butts DA, Shatz CJ
  Proc Natl Acad Sci U S A. 2007
  PubMed ID: 17420446
   
  
• Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes.
  Leng Q, Ge Q, Nguyen T, Eisen HN, Chen J
  Proc Natl Acad Sci U S A. 2007
  PubMed ID: 17360333
   
  
• [Study on the association between polymorphism of TAP1 637 A/G alleles polymorphism and metabolic syndrome]
  Hu XS, Guo ZR, Shen C, Wu M, Yu RB, Yao CL
  Zhonghua Liu Xing Bing Xue Za Zhi. 2007
  PubMed ID: 17649665
   
  
• The role of TAP1 and TAP2 gene polymorphism in idiopathic bronchiectasis in children.
  Doğru D, Ozbaş Gerçeker F, Yalçin E, Cobanoğlu N, Pekcan S, Ozçelik U, Kiper N, Ozgüç M
  Pediatr Pulmonol. 2007
  PubMed ID: 17245734
   
  
• Mechanism of substrate sensing and signal transmission within an ABC transporter: use of a Trojan horse strategy.
  Herget M, Oancea G, Schrodt S, Karas M, Tampé R, Abele R
  J Biol Chem. 2007
  PubMed ID: 17164240
   
  
• The varicellovirus-encoded TAP inhibitor UL49.5 regulates the presentation of CTL epitopes by Qa-1b1.
  van Hall T, Laban S, Koppers-Lalic D, Koch J, Precup C, Asmawidjaja P, Offringa R, Wiertz EJ
  J Immunol. 2007
  PubMed ID: 17202325
   
  
• Phenotypic studies of natural killer cell subsets in human transporter associated with antigen processing deficiency.
  Zimmer J, Bausinger H, Andrès E, Donato L, Hanau D, Hentges F, Moretta A, de la Salle H
  PLoS ONE. 2007
  PubMed ID: 17940597
   
  
• In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.
  Hammer GE, Gonzalez F, James E, Nolla H, Shastri N
  Nat Immunol. 2007
  PubMed ID: 17128277
   
  
• Catalytic site modifications of TAP1 and TAP2 and their functional consequences.
  Perria CL, Rajamanickam V, Lapinski PE, Raghavan M
  J Biol Chem. 2006
  PubMed ID: 17068338
   
  
• Reduced cytokine-mediated up-regulation of HLA-DR in TAP-deficient fibroblasts.
  Zimmer J, Poli A, Andrès E, Hanau D, Brons NH, Hentges F
  Immunol Lett. 2006
  PubMed ID: 16956670
   
  
• Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.
  Park B, Lee S, Kim E, Cho K, Riddell SR, Cho S, Ahn K
  Cell. 2006
  PubMed ID: 17055437
   
  
• Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.
  Lucas PJ, Kim SJ, Mackall CL, Telford WG, Chu YW, Hakim FT, Gress RE
  Blood. 2006
  PubMed ID: 16788095
   
  
• Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter.
  Procko E, Ferrin-O'Connell I, Ng SL, Gaudet R
  Mol Cell. 2006
  PubMed ID: 17018292
   
  
• No difference in polymorphism frequency in a Turkish population with allergic rhinitis.
  Yilmaz I, Atac FB, Erkan AN, Verdi H, Cagici CA, Aslan S, Sahin FI, Ozluoglu LN
  Acta Otolaryngol. 2006
  PubMed ID: 16923719
   
  
• PirB restricts ocular-dominance plasticity in visual cortex.
  Syken J, Grandpre T, Kanold PO, Shatz CJ
  Science. 2006
  PubMed ID: 16917027
   
  
• Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo.
  Bertholet S, Goldszmid R, Morrot A, Debrabant A, Afrin F, Collazo-Custodio C, Houde M, Desjardins M, Sher A, Sacks D
  J Immunol. 2006
  PubMed ID: 16951311
   
  
• Engineering ATPase activity in the isolated ABC cassette of human TAP1.
  Ernst R, Koch J, Horn C, Tampé R, Schmitt L
  J Biol Chem. 2006
  PubMed ID: 16864587
   
  
• Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread.
  Hangartner L, Zellweger RM, Giobbi M, Weber J, Eschli B, McCoy KD, Harris N, Recher M, Zinkernagel RM, Hengartner H
  J Exp Med. 2006
  PubMed ID: 16880253
   
  
• TAP1-/- mice present oligoclonal BV-BJ expansions following the rejection of grafts bearing self antigens.
  Marrero I, Huffman D, Kalil J, Sercarz EE, Coelho V
  Immunology. 2006
  PubMed ID: 16895555
   
  
• The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding.
  Koch J, Guntrum R, Tampé R
  FEBS Lett. 2006
  PubMed ID: 16828748
   
  
• Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2.
  Keusekotten K, Leonhardt RM, Ehses S, Knittler MR
  J Biol Chem. 2006
  PubMed ID: 16624807
   
  
• Bovine herpesvirus 1 UL49.5 protein inhibits the transporter associated with antigen processing despite complex formation with glycoprotein M.
  Lipińska AD, Koppers-Lalic D, Rychłowski M, Admiraal P, Rijsewijk FA, Bieńkowska-Szewczyk K, Wiertz EJ
  J Virol. 2006
  PubMed ID: 16731921
   
  
• Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.
  Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H
  Nat Immunol. 2006
  PubMed ID: 16604075
   
  
• Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis.
  Gomez LM, Camargo JF, Castiblanco J, Ruiz-Narváez EA, Cadena J, Anaya JM
  Tissue Antigens. 2006
  PubMed ID: 16634865
   
  
• [Investigating the correlation between polymorphisms with couple sharing rate of TAP gene and hypertensive disorder complicating pregnancy]
  Gao MY, Wu AH, Wen CX, She DX, Chen SQ
  Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006
  PubMed ID: 16604487
   
  
• BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
  Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
  PLoS Biol. 2006
  PubMed ID: 16602821
   
  
• Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.
  van Hall T, Wolpert EZ, van Veelen P, Laban S, van der Veer M, Roseboom M, Bres S, Grufman P, de Ru A, Meiring H, de Jong A, Franken K, Teixeira A, Valentijn R, Drijfhout JW, Koning F, Camps M, Ossendorp F, Kärre K, Ljunggren HG, Melief CJ, Offringa R
  Nat Med. 2006
  PubMed ID: 16550190
   
  
• In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules.
  Yan J, Parekh VV, Mendez-Fernandez Y, Olivares-Villagómez D, Dragovic S, Hill T, Roopenian DC, Joyce S, Van Kaer L
  J Exp Med. 2006
  PubMed ID: 16505142
   
  
• Membrane topology of the transporter associated with antigen processing (TAP1) within an assembled functional peptide-loading complex.
  Schrodt S, Koch J, Tampé R
  J Biol Chem. 2006
  PubMed ID: 16407277
   
  
• Physical and functional interactions of the cytomegalovirus US6 glycoprotein with the transporter associated with antigen processing.
  Halenius A, Momburg F, Reinhard H, Bauer D, Lobigs M, Hengel H
  J Biol Chem. 2006
  PubMed ID: 16356928
   
  
• Identification and characterization of mouse PSF1-binding protein, SLD5.
  Kong L, Ueno M, Itoh M, Yoshioka K, Takakura N
  Biochem Biophys Res Commun. 2006
  PubMed ID: 16338220
   
  
• The delivery of an antigen from the endocytic compartment into the cytosol for cross-presentation is restricted to early immature dendritic cells.
  Hotta C, Fujimaki H, Yoshinari M, Nakazawa M, Minami M
  Immunology. 2006
  PubMed ID: 16423045
   
  
• The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules.
  Hammer GE, Gonzalez F, Champsaur M, Cado D, Shastri N
  Nat Immunol. 2006
  PubMed ID: 16299505
   
  
• The intracellular antigen transport machinery TAP in adaptive immunity and virus escape mechanisms.
  Schölz C, Tampé R
  J Bioenerg Biomembr. 2005
  PubMed ID: 16691491
   
  
• PSF1 is essential for early embryogenesis in mice.
  Ueno M, Itoh M, Kong L, Sugihara K, Asano M, Takakura N
  Mol Cell Biol. 2005
  PubMed ID: 16287864
   
  
• No association between TAP1 DpnII polymorphism and bronchopulmonary dysplasia.
  Lin HC, Su BH, Hsu CM, Chou IC, Wu KH, Lin HC, Tsai FJ, Tsai CH
  Acta Paediatr Taiwan. 2005
  PubMed ID: 16640035
   
  
• Towards a proteome-scale map of the human protein-protein interaction network.
  Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M
  Nature. 2005
  PubMed ID: 16189514
   
  
• SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential.
  Davey GM, Starr R, Cornish AL, Burghardt JT, Alexander WS, Carbone FR, Surh CD, Heath WR
  J Exp Med. 2005
  PubMed ID: 16216888
   
  
• Cutting edge: differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation.
  Jabbari A, Harty JT
  J Immunol. 2005
  PubMed ID: 16210583
   
  
• Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I.
  Procko E, Raghuraman G, Wiley DC, Raghavan M, Gaudet R
  Immunol Cell Biol. 2005
  PubMed ID: 16174096
   
  
• A requirement for sustained ERK signaling during thymocyte positive selection in vivo.
  McNeil LK, Starr TK, Hogquist KA
  Proc Natl Acad Sci U S A. 2005
  PubMed ID: 16174747
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge.
  Uldrich AP, Crowe NY, Kyparissoudis K, Pellicci DG, Zhan Y, Lew AM, Bouillet P, Strasser A, Smyth MJ, Godfrey DI
  J Immunol. 2005
  PubMed ID: 16116198
   
  
• Enhancement of dendritic cell antigen cross-presentation by CpG DNA involves type I IFN and stabilization of class I MHC mRNA.
  Kuchtey J, Chefalo PJ, Gray RC, Ramachandra L, Harding CV
  J Immunol. 2005
  PubMed ID: 16081792
   
  
• Exploring the minimal functional unit of the transporter associated with antigen processing.
  Koch J, Guntrum R, Tampé R
  FEBS Lett. 2005
  PubMed ID: 16061226
   
  
• TAP1 and TAP2 polymorphisms and their linkage disequilibrium with HLA-DR, -DP, and -DQ in an eastern Andalusian population.
  Alvarado-Guerri R, Cabrera CM, Garrido F, López-Nevot MA
  Hum Immunol. 2005
  PubMed ID: 16216677
   
  
• Autoreactivity to self H-2Kb peptides in TAP1 mice. Intravenous administration of H-2Kb class I-derived peptides induces long-term survival of grafts from C57BL/6 donors.
  Marrero I, Benvenutti LA, Kalil J, Coelho V
  Immunology. 2005
  PubMed ID: 16011517
   
  
• Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway.
  Chen M, Tabaczewski P, Truscott SM, Van Kaer L, Stroynowski I
  J Immunol. 2005
  PubMed ID: 16002705
   
  
• Association of TAP1 and TAP2 gene polymorphisms with systemic sclerosis in Korean patients.
  Song YW, Lee EB, Whang DH, Kang SJ, Takeuchi F, Park MH
  Hum Immunol. 2005
  PubMed ID: 16112028
   
  
• Mouse endothelial cells cross-present lymphocyte-derived antigen on class I MHC via a TAP1- and proteasome-dependent pathway.
  Bagai R, Valujskikh A, Canaday DH, Bailey E, Lalli PN, Harding CV, Heeger PS
  J Immunol. 2005
  PubMed ID: 15944272
   
  
• Impaired transporter associated with antigen processing-dependent peptide transport during productive EBV infection.
  Ressing ME, Keating SE, van Leeuwen D, Koppers-Lalic D, Pappworth IY, Wiertz EJ, Rowe M
  J Immunol. 2005
  PubMed ID: 15905524
   
  
• A rare transporter associated with antigen processing polymorphism overpresented in HLAlow colon cancer reveals the functional significance of the signature domain in antigen processing.
  Yang T, Lapinski PE, Zhao H, Zhou Q, Zhang H, Raghavan M, Liu Y, Zheng P
  Clin Cancer Res. 2005
  PubMed ID: 15897556
   
  
• Analysis of TAP1 and TAP2 polymorphism of mother-infant in Chinese patients with pre-eclampsia.
  Zhang Z, Jia L, Hou L, Xiong P, Wu X, Wang X, Huang Y, Ke H, Chang C, Cui S, Gong F
  Cell Mol Immunol. 2005
  PubMed ID: 16191421
   
  
• IFN regulatory factor-2 cooperates with STAT1 to regulate transporter associated with antigen processing-1 promoter activity.
  Rouyez MC, Lestingi M, Charon M, Fichelson S, Buzyn A, Dusanter-Fourt I
  J Immunol. 2005
  PubMed ID: 15778351
   
  
• A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent.
  Tewari MK, Sinnathamby G, Rajagopal D, Eisenlohr LC
  Nat Immunol. 2005
  PubMed ID: 15711549
   
  
• Cutting edge: antibody production to pneumococcal polysaccharides requires CD1 molecules and CD8+ T cells.
  Kobrynski LJ, Sousa AO, Nahmias AJ, Lee FK
  J Immunol. 2005
  PubMed ID: 15699104
   
  
• Normal hematopoiesis is maintained by activated bone marrow CD4+ T cells.
  Monteiro JP, Benjamin A, Costa ES, Barcinski MA, Bonomo A
  Blood. 2005
  PubMed ID: 15514013
   
  
• Polymorphisms of transporter associated with antigen processing type 1 (TAP1), proteasome subunit beta type 9 (PSMB9) and their common promoter in African children with different manifestations of malaria.
  Niesporek S, Meyer CG, Kremsner PG, May J
  Int J Immunogenet. 2005
  PubMed ID: 15686587
   
  
• TAP 2 gene Msp-I polymorphism might be associated with calcium oxalate stone disease.
  Huang SH, Chen RH, Wan L, Tsai FJ, Chen WC
  Urol Int. 2005
  PubMed ID: 16215317
   
  
• Gene and alternative splicing annotation with AIR.
  Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
  Genome Res. 2005
  PubMed ID: 15632090
   
  
• Functional role of C-terminal sequence elements in the transporter associated with antigen processing.
  Ehses S, Leonhardt RM, Hansen G, Knittler MR
  J Immunol. 2005
  PubMed ID: 15611256
   
  
• Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome.
  Begley GS, Horvath AR, Taylor JC, Higgins CF
  Mol Immunol. 2005
  PubMed ID: 15488952
   
  
• A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy.
  Oliveira AL, Thams S, Lidman O, Piehl F, Hökfelt T, Kärre K, Lindå H, Cullheim S
  Proc Natl Acad Sci U S A. 2004
  PubMed ID: 15591351
   
  
• Membrane localization of transporter associated with antigen processing (TAP)-like (ABCB9) visualized in vivo with a fluorescence protein-fusion technique.
  Kobayashi A, Maeda T, Maeda M
  Biol Pharm Bull. 2004
  PubMed ID: 15577206
   
  
• Lack of a strong association between HLA class II, tumour necrosis factor and transporter associated with antigen processing gene polymorphisms and virological response to alpha-interferon treatment in patients with chronic hepatitis C.
  Airoldi A, Zavaglia C, Silini E, Tinelli C, Martinetti M, Asti M, Rossini A, Vangeli M, Salvaneschi L, Pinzello G
  Eur J Immunogenet. 2004
  PubMed ID: 15548263
   
  
• Homeostatic proliferation of a Qa-1b-restricted T cell: a distinction between the ligands required for positive selection and for proliferation in lymphopenic hosts.
  Sullivan BA, Reed-Loisel LM, Kersh GJ, Jensen PE
  J Immunol. 2004
  PubMed ID: 15528342
   
  
• Detection of TAP family dimerizations by an in vivo assay in mammalian cells.
  Leveson-Gower DB, Michnick SW, Ling V
  Biochemistry. 2004
  PubMed ID: 15518576
   
  
• Association between the TAP1 gene codon 637 polymorphism and Graves' disease.
  Chen RH, Chen WC, Chen CC, Tsai CH, Tsai FJ
  Endocrine. 2004
  PubMed ID: 15711027
   
  
• HLA-DRB1, TAP2/TAP1, and HLA-DPB1 haplotypes in Finnish juvenile idiopathic arthritis: more complexity within the MHC.
  Runstadler JA, Säilä H, Savolainen A, Leirisalo-Repo M, Aho K, Tuomilehto-Wolf E, Tuomilehto J, Seldin MF
  Genes Immun. 2004
  PubMed ID: 15343265
   
  
• Functional non-equivalence of ATP-binding cassette signature motifs in the transporter associated with antigen processing (TAP).
  Chen M, Abele R, Tampé R
  J Biol Chem. 2004
  PubMed ID: 15322097
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to Qa-1b-restricted CTLs.
  Li L, Sullivan BA, Aldrich CJ, Soloski MJ, Forman J, Grandea AG, Jensen PE, Van Kaer L
  J Immunol. 2004
  PubMed ID: 15356116
   
  
• Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo.
  Shen L, Sigal LJ, Boes M, Rock KL
  Immunity. 2004
  PubMed ID: 15308097
   
  
• STAT1 regulates lipopolysaccharide- and TNF-alpha-dependent expression of transporter associated with antigen processing 1 and low molecular mass polypeptide 2 genes in macrophages by distinct mechanisms.
  Marqués L, Brucet M, Lloberas J, Celada A
  J Immunol. 2004
  PubMed ID: 15240699
   
  
• Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus.
  Belz GT, Smith CM, Kleinert L, Reading P, Brooks A, Shortman K, Carbone FR, Heath WR
  Proc Natl Acad Sci U S A. 2004
  PubMed ID: 15163797
   
  
• Rejection of grafts without histocompatibility antigen disparity by TAP1-/- mice: a role for CD4+ T cells.
  Marrero I, Benvenutti LA, Noronha I, Kalil J, Coelho V
  Transplant Proc. 2004
  PubMed ID: 15194347
   
  
• The genetic association database.
  Becker KG, Barnes KC, Bright TJ, Wang SA
  Nat Genet. 2004
  PubMed ID: 15118671
   
  
• Polymorphisms of TAP1 transporter genes in Chinese patients with systemic lupus erythematosus in Taiwan.
  Huang CM, Hang LW, Chen CL, Wu JY, Tsai FJ
  Rheumatol Int. 2004
  PubMed ID: 12827444
   
  
• High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
  Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
  Genome Res. 2004
  PubMed ID: 15060019
   
  
• The genomic sequence and comparative analysis of the rat major histocompatibility complex.
  Hurt P, Walter L, Sudbrak R, Klages S, Müller I, Shiina T, Inoko H, Lehrach H, Günther E, Reinhardt R, Himmelbauer H
  Genome Res. 2004
  PubMed ID: 15060004
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
  PubMed ID: 15057822
   
  
• Prolonged antigen presentation, APC-, and CD8+ T cell turnover during mycobacterial infection: comparison with Listeria monocytogenes.
  van Faassen H, Dudani R, Krishnan L, Sad S
  J Immunol. 2004
  PubMed ID: 15004149
   
  
• Functional dissection of the transmembrane domains of the transporter associated with antigen processing (TAP).
  Koch J, Guntrum R, Heintke S, Kyritsis C, Tampé R
  J Biol Chem. 2004
  PubMed ID: 14679198
   
  
• Polymorphism of transporter associated with antigen presentation 1 as a potential determinant for severity of disease in recurrent respiratory papillomatosis caused by human papillomavirus types 6 and 11.
  Vambutas A, Bonagura VR, Reed EF, Abramson AL, Mullooly V, DeVoti J, Gjertson DW, Steinberg BM
  J Infect Dis. 2004
  PubMed ID: 14976605
   
  
• p38 activation through Toll-like receptors modulates IFN-gamma-induced expression of the Tap-1 gene only in macrophages.
  Cecil AA, Klemsz MJ
  J Leukoc Biol. 2004
  PubMed ID: 14694183
   
  
• Association of TAP2 gene polymorphisms in Chinese patients with rheumatoid arthritis.
  Yu MC, Huang CM, Wu MC, Wu JY, Tsai FJ
  Clin Rheumatol. 2004
  PubMed ID: 14749980
   
  
• Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis.
  Feng HM, Walker DH
  Infect Immun. 2004
  PubMed ID: 14742542
   
  
• Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain.
  Lilić M, Popmihajlov Z, Monaco JJ, Vukmanović S
  Immunogenetics. 2004
  PubMed ID: 14735325
   
  
• Transporter associated with antigen processing gene 1 codon 333 and codon 637 polymorphisms are associated with primary open-angle glaucoma.
  Lin HJ, Tsai CH, Tsai FJ, Chen WC, Chen HY, Fan SS
  Mol Diagn. 2004
  PubMed ID: 15887980
   
  
• Polymorphism of the TAP1 gene in Polish patients with psoriasis vulgaris.
  Witkowska-Toboła AM, Szczerkowska-Dobosz A, Nedoszytko B, Roszkiewicz J
  J Appl Genet. 2004
  PubMed ID: 15306733
   
  
• Complete sequencing and characterization of 21,243 full-length human cDNAs.
  Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
  Nat Genet. 2004
  PubMed ID: 14702039
   
  
• NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy.
  Hayakawa Y, Screpanti V, Yagita H, Grandien A, Ljunggren HG, Smyth MJ, Chambers BJ
  J Immunol. 2004
  PubMed ID: 14688317
   
  
• Splenic B cells act as antigen presenting cells for the induction of anterior chamber-associated immune deviation.
  Skelsey ME, Mayhew E, Niederkorn JY
  Invest Ophthalmol Vis Sci. 2003
  PubMed ID: 14638723
   
  
• The distinct nucleotide binding states of the transporter associated with antigen processing (TAP) are regulated by the nonhomologous C-terminal tails of TAP1 and TAP2.
  Bouabe H, Knittler MR
  Eur J Biochem. 2003
  PubMed ID: 14622282
   
  
• The DNA sequence and analysis of human chromosome 6.
  Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S
  Nature. 2003
  PubMed ID: 14574404
   
  
• [Expression of transporter associated with antigen processing (TAP) in childhood acute leukemia and its clinical significance]
  Xie JJ, Hu YM, Lu YY, Li ZG, Gong WY, Yu SM, Sun J
  Ai Zheng. 2003
  PubMed ID: 14558951
   
  
• Genes of the LMP/TAP cluster are associated with the human autoimmune disease vitiligo.
  Casp CB, She JX, McCormack WT
  Genes Immun. 2003
  PubMed ID: 14551602
   
  
• Peptides induce ATP hydrolysis at both subunits of the transporter associated with antigen processing.
  Chen M, Abele R, Tampé R
  J Biol Chem. 2003
  PubMed ID: 12777379
   
  
• Novel TAP1 polymorphisms in indigenous Zimbabweans: their potential implications on TAP function and in human diseases.
  Lajoie J, Zijenah LS, Faucher MC, Ward BJ, Roger M, ZVITAMBO Study Group
  Hum Immunol. 2003
  PubMed ID: 12878362
   
  
• Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity.
  Herzer K, Falk CS, Encke J, Eichhorst ST, Ulsenheimer A, Seliger B, Krammer PH
  J Virol. 2003
  PubMed ID: 12857899
   
  
• Characterization of extrathymic CD8 alpha beta T cells in the liver and intestine in TAP-1 deficient mice.
  Tsukada C, Miyaji C, Kawamura H, Miyakawa R, Yokoyama H, Ishimoto Y, Miyazawa S, Watanabe H, Abo T
  Immunology. 2003
  PubMed ID: 12807479
   
  
• Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2.
  Konno T, Ebihara T, Hisaeda K, Uchiumi T, Nakamura T, Shirakusa T, Kuwano M, Wada M
  J Biol Chem. 2003
  PubMed ID: 12682044
   
  
• Tapasin-/- and TAP1-/- macrophages are deficient in vacuolar alternate class I MHC (MHC-I) processing due to decreased MHC-I stability at phagolysosomal pH.
  Chefalo PJ, Grandea AG, Van Kaer L, Harding CV
  J Immunol. 2003
  PubMed ID: 12794107
   
  
• Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.
  TeKippe M, Harrison DE, Chen J
  Exp Hematol. 2003
  PubMed ID: 12829028
   
  
• Lack of association between transporter associated with antigen processing (TAP) and HLA-DM gene polymorphisms and antibody levels following measles vaccination.
  Dhiman N, Ovsyannikova IG, Pinsky NA, Vierkant RA, Jacobsen SJ, Jacobson RM, Poland GA
  Eur J Immunogenet. 2003
  PubMed ID: 12786997
   
  
• Association of TAP1 downregulation in human primary melanoma lesions with lack of spontaneous regression.
  Dissemond J, Götte P, Mörs J, Lindeke A, Goos M, Ferrone S, Wagner SN
  Melanoma Res. 2003
  PubMed ID: 12777979
   
  
• Association of transporter associated with antigen processing genes with Behçet's disease in Japanese.
  Takizawa K, Takeuchi F, Nabeta H, Hirohata S, Takeuchi A, Matsumura Y, Yamamoto K
  Autoimmunity. 2003
  PubMed ID: 12911283
   
  
• A single-nucleotide deletion leads to rapid degradation of TAP-1 mRNA in a melanoma cell line.
  Yang T, McNally BA, Ferrone S, Liu Y, Zheng P
  J Biol Chem. 2003
  PubMed ID: 12582163
   
  
• A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells.
  Datta SK, Redecke V, Prilliman KR, Takabayashi K, Corr M, Tallant T, DiDonato J, Dziarski R, Akira S, Schoenberger SP, Raz E
  J Immunol. 2003
  PubMed ID: 12682240
   
  
• Polymorphisms of the TAP1 and TAP2 genes in human alveolar echinococcosis.
  Zhang S, Penfornis A, Harraga S, Chabod J, Beurton I, Bresson-Hadni S, Tiberghien P, Kern P, Vuitton DA
  Eur J Immunogenet. 2003
  PubMed ID: 12648282
   
  
• Association of TAP and HLA-DM genes with psoriasis in Koreans.
  Pyo CW, Hur SS, Kim YK, Kim TY, Kim TG
  J Invest Dermatol. 2003
  PubMed ID: 12648225
   
  
• TAP1 and TAP2 polymorphisms analysis in northwestern Colombian patients with systemic lupus erythematosus.
  Correa PA, Molina JF, Pinto LF, Arcos-Burgos M, Herrera M, Anaya JM
  Ann Rheum Dis. 2003
  PubMed ID: 12634240
   
  
• Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1.
  Treiner E, Duban L, Bahram S, Radosavljevic M, Wanner V, Tilloy F, Affaticati P, Gilfillan S, Lantz O
  Nature. 2003
  PubMed ID: 12634786
   
  
• CD8+ T cells accumulate in the lungs of Mycobacterium tuberculosis-infected Kb-/-Db-/- mice, but provide minimal protection.
  Urdahl KB, Liggitt D, Bevan MJ
  J Immunol. 2003
  PubMed ID: 12574368
   
  
• The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP.
  Hewitt EW, Lehner PJ
  Eur J Immunol. 2003
  PubMed ID: 12645939
   
  
• HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.
  Izmailova E, Bertley FM, Huang Q, Makori N, Miller CJ, Young RA, Aldovini A
  Nat Med. 2003
  PubMed ID: 12539042
   
  
• Functional cysteine-less subunits of the transporter associated with antigen processing (TAP1 and TAP2) by de novo gene assembly.
  Heintke S, Chen M, Ritz U, Lankat-Buttgereit B, Koch J, Abele R, Seliger B, Tampé R
  FEBS Lett. 2003
  PubMed ID: 12505156
   
  
• Association of the TAP2*Bky2 allele with presence of SS-A/Ro and other autoantibodies in Japanese patients with systemic lupus erythematosus.
  Kanagawa S, Morinobu A, Koshiba M, Kageyama G, Hayashi N, Yoshino S, Tokano Y, Hashimoto H, Kumagai S
  Lupus. 2003
  PubMed ID: 12729048
   
  
• TAP1 gene AccI polymorphism is associated with atopic bronchial asthma.
  Hang LW, Hsia TC, Chen WC, Chen HY, Tsai FJ
  J Clin Lab Anal. 2003
  PubMed ID: 12640628
   
  
• A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.
  Garbi N, Tiwari N, Momburg F, Hämmerling GJ
  Eur J Immunol. 2003
  PubMed ID: 12594855
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
  Rudolph MG, Stevens J, Speir JA, Trowsdale J, Butcher GW, Joly E, Wilson IA
  J Mol Biol. 2002
  PubMed ID: 12470953
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis.
  Corr M, Crain B
  J Immunol. 2002
  PubMed ID: 12444173
   
  
• [Antigen transporter gene polymorphism and predisposition to Graves disease: a preliminary analysis]
  Cai M, Yan L, Cheng H, Ding H, Fu Z
  Zhonghua Nei Ke Za Zhi. 2002
  PubMed ID: 12485523
   
  
• The role of fibroblasts in thymocyte-positive selection.
  Lilić M, Santori FR, Neilson EG, Frey AB, Vukmanović S
  J Immunol. 2002
  PubMed ID: 12391207
   
  
• Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes.
  Raghuraman G, Lapinski PE, Raghavan M
  J Biol Chem. 2002
  PubMed ID: 12213826
   
  
• Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d/NKT cell pathway.
  Procópio DO, Almeida IC, Torrecilhas AC, Cardoso JE, Teyton L, Travassos LR, Bendelac A, Gazzinelli RT
  J Immunol. 2002
  PubMed ID: 12244192
   
  
• A single nucleotide polymorphism of the low molecular mass polypeptide 7 gene influences the interferon response in patients with chronic hepatitis C.
  Sugimoto Y, Kuzushita N, Takehara T, Kanto T, Tatsumi T, Miyagi T, Jinushi M, Ohkawa K, Horimoto M, Kasahara A, Hori M, Sasaki Y, Hayashi N
  J Viral Hepat. 2002
  PubMed ID: 12225333
   
  
• Differential regulation of the expression of transporters associated with antigen processing, TAP1 and TAP2, by cytokines and lipopolysaccharide in primary human macrophages.
  Schiffer R, Baron J, Dagtekin G, Jahnen-Dechent W, Zwadlo-Klarwasser G
  Inflamm Res. 2002
  PubMed ID: 12234057
   
  
• Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits.
  Antoniou AN, Ford S, Pilley ES, Blake N, Powis SJ
  Immunology. 2002
  PubMed ID: 12047747
   
  
• TAP1 and TAP2 gene polymorphism in rheumatoid arthritis in a population in eastern France.
  Zhang SL, Chabod J, Penfornis A, Reviron D, Tiberghien P, Wendling D, Toussirot E
  Eur J Immunogenet. 2002
  PubMed ID: 12047361
   
  
• Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum.
  Paulsson KM, Kleijmeer MJ, Griffith J, Jevon M, Chen S, Anderson PO, Sjogren HO, Li S, Wang P
  J Biol Chem. 2002
  PubMed ID: 11884415
   
  
• Lack of association between gene polymorphism of transporters associated with antigen processing and allergic rhinitis in a Japanese population.
  Takeuchi K, Abe S, Masuda S, Yuta A, Majima Y, Sakakura Y
  Ann Otol Rhinol Laryngol. 2002
  PubMed ID: 12018331
   
  
• Analysis of the modifying effects of TAP 1/2 genes on cystic fibrosis phenotype.
  Ozbaş-Gerçeker F, Ozçelik U, Kiper N, Anadol D, Ayhan G, Yilmaz E, Erdem-Yurter H, Ozgüç M
  Turk J Pediatr. 2002
  PubMed ID: 12026214
   
  
• Distribution of TAP gene polymorphisms and extended MHC haplotypes in Mexican Mestizos and in Seri Indians from northwest Mexico.
  Balladares S, Alaez C, Pujol J, Duran C, Navarro JL, Gorodezky C
  Genes Immun. 2002
  PubMed ID: 11960305
   
  
• Cross-presentation of virus-like particles by skin-derived CD8(-) dendritic cells: a dispensable role for TAP.
  Ruedl C, Storni T, Lechner F, Bächi T, Bachmann MF
  Eur J Immunol. 2002
  PubMed ID: 11870626
   
  
• Evidences of conformational changes in class II Major Histocompatibility Complex molecules that affect the immunogenicity.
  Neveu R, Auriault C, Angyalosi G, Georges B
  Mol Immunol. 2002
  PubMed ID: 11858821
   
  
• High frequency of a non-functional TAP1/LMP2 promoter polymorphism in human tumors.
  Seliger B, Bock M, Ritz U, Huber C
  Int J Oncol. 2002
  PubMed ID: 11788900
   
  
• Three-dimensional structure of transporter associated with antigen processing (TAP) obtained by single Particle image analysis.
  Velarde G, Ford RC, Rosenberg MF, Powis SJ
  J Biol Chem. 2001
  PubMed ID: 11595746
   
  
• Distribution of HLA-A, B alleles and polymorphisms of TAP and LMP genes in Korean patients with atopic dermatitis.
  Lee HJ, Ha SJ, Han H, Kim JW
  Clin Exp Allergy. 2001
  PubMed ID: 11737038
   
  
• Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.
  Gaudet R, Wiley DC
  EMBO J. 2001
  PubMed ID: 11532960
   
  
• The interaction of the polymorphisms in transporter of antigen peptides (TAP) and lymphotoxin alpha (LT-alpha) genes and atopic diseases in the Czech population.
  Izakovicová Hollá L, Vasků A, Izakovic V, Znojil V
  Clin Exp Allergy. 2001
  PubMed ID: 11591192
   
  
• Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains.
  Daumke O, Knittler MR
  Eur J Biochem. 2001
  PubMed ID: 11532014
   
  
• The source of early IFN-gamma that plays a role in Th1 priming.
  Das G, Sheridan S, Janeway CA
  J Immunol. 2001
  PubMed ID: 11489982
   
  
• Functional roles of TAP and tapasin in the assembly of M3-N-formylated peptide complexes.
  Chun T, Grandea AG, Lybarger L, Forman J, Van Kaer L, Wang CR
  J Immunol. 2001
  PubMed ID: 11466371
   
  
• Polymorphism of Immune Response Genes as a Factor for Predisposition to Development of Diseases.
  Konenkov VI, Prokofiev VF, Shevchenko AV, Golovanova OV, Smolnikova MV
  Russ J Immunol. 2001
  PubMed ID: 12687213
   
  
• Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP).
  Karttunen JT, Lehner PJ, Gupta SS, Hewitt EW, Cresswell P
  Proc Natl Acad Sci U S A. 2001
  PubMed ID: 11381133
   
  
• Differential involvement of dendritic cell subsets during acute Salmonella infection.
  Kirby AC, Yrlid U, Svensson M, Wick MJ
  J Immunol. 2001
  PubMed ID: 11359839
   
  
• A low affinity TCR ligand restores positive selection of CD8+ T cells in vivo.
  Stefanski HE, Mayerova D, Jameson SC, Hogquist KA
  J Immunol. 2001
  PubMed ID: 11359813
   
  
• Modulation of CD8+ T cell response to antigen by the levels of self MHC class I.
  Santori FR, Arsov I, Vukmanović S
  J Immunol. 2001
  PubMed ID: 11313378
   
  
• The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families.
  Park SH, Weiss A, Benlagha K, Kyin T, Teyton L, Bendelac A
  J Exp Med. 2001
  PubMed ID: 11304550
   
  
• Induction of herpes simplex virus gB-specific cytotoxic T lymphocytes in TAP1-deficient mice by genetic immunization but not HSV infection.
  Paliard X, Doe B, Selby MJ, Hartog K, Lee AY, Burke RL, Walker CM
  Virology. 2001
  PubMed ID: 11259190
   
  
• Novel alleles at the lymphotoxin alpha (LTalpha) locus mark extended HLA haplotypes in native Africans.
  Tang J, Myracle AD, Allen S, Karita E, Musonda R, Fultz PN, Kaslow RA
  Hum Immunol. 2001
  PubMed ID: 11250044
   
  
• TAPI polymorphisms in several human ethnic groups: characteristics, evolution, and genotyping strategies.
  Tang J, Freedman DO, Allen S, Karita E, Musonda R, Braga C, Margolick J, Kaslow RA
  Hum Immunol. 2001
  PubMed ID: 11250043
   
  
• Spontaneous inflammatory disease in HLA-B27 transgenic mice does not require transporter of antigenic peptides.
  Khare SD, Lee S, Bull MJ, Hanson J, Luthra HS, David CS
  Clin Immunol. 2001
  PubMed ID: 11237560
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• Systemic deficits in transporter for antigen presentation (TAP)-1 or proteasome subunit LMP2 have little or no effect on tumor incidence.
  Johnsen AK, France J, Nagy N, Askew D, Abdul-Karim FW, Gerson SL, Sy MS, Harding CV
  Int J Cancer. 2001
  PubMed ID: 11169961
   
  
• The human cytomegalovirus gene product US6 inhibits ATP binding by TAP.
  Hewitt EW, Gupta SS, Lehner PJ
  EMBO J. 2001
  PubMed ID: 11157746
   
  
• Regulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequences.
  Saveanu L, Van Endert PM
  Adv Exp Med Biol. 2001
  PubMed ID: 11774612
   
  
• Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function.
  Ritz U, Momburg F, Pircher HP, Strand D, Huber C, Seliger B
  Int Immunol. 2001
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