SMARCC1

Summary Top Help

Gene Description:

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

Synonyms:

BAF155, AI115498, SMARCC1, Smarcc1, Rsc8, SRG3, CRACC1, SWI3

Orthologs:

Human SMARCC1 (protein-coding), Mouse Smarcc1 (protein-coding), Rat Smarcc1 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr3:47626762..47823596 (196.83 kb) View in Genome Browser

(Mouse) NCBIM37 - chr9:110034528..110142682 (108.15 kb) View in Genome Browser

(Rat) RGSC3.4 - chr8:114484491..114611663 (127.17 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for SMARCC1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for SMARCC1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: 2

Reactome: None available

NCI-Nature Pathway Interaction Database: 2

Gene Ontology: 22

Publications from PubMed Top Help

Publications: 148

A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.
VanDunk C, Hunter LA, Gray PA
J Neurosci. 2011
PubMed ID: 21525287
Target genes of the largest human SWI/SNF complex subunit control cell growth.
Inoue H, Giannakopoulos S, Parkhurst CN, Matsumura T, Kono EA, Furukawa T, Tanese N
Biochem J. 2011
PubMed ID: 21118156
Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression.
Ahn J, Ko M, Lee C, Kim J, Yoon H, Seong RH
Oncogene. 2011
PubMed ID: 20935679
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.
Miller SA, Mohn SE, Weinmann AS
Mol Cell. 2010
PubMed ID: 21095589
Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex.
Keppler BR, Archer TK
J Biol Chem. 2010
PubMed ID: 20829358
The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes.
Bakshi R, Hassan MQ, Pratap J, Lian JB, Montecino MA, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS
J Cell Physiol. 2010
PubMed ID: 20506188
Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.
Tando T, Ishizaka A, Watanabe H, Ito T, Iida S, Haraguchi T, Mizutani T, Izumi T, Isobe T, Akiyama T, Inoue J, Iba H
J Biol Chem. 2010
PubMed ID: 20460684
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner.
Seki Y, Kurisaki A, Watanabe-Susaki K, Nakajima Y, Nakanishi M, Arai Y, Shiota K, Sugino H, Asashima M
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20508149
Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor alpha through histone deacetylase 1.
Matsuyama R, Takada I, Yokoyama A, Fujiyma-Nakamura S, Tsuji N, Kitagawa H, Fujiki R, Kim M, Kouzu-Fujita M, Yano T, Kato S
J Biol Chem. 2010
PubMed ID: 20400511
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM
Science. 2010
PubMed ID: 20360068
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Dev Cell. 2010
PubMed ID: 20412781
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.
Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu MM, Choudhary J
Cell Stem Cell. 2010
PubMed ID: 20362542
An Oct4-centered protein interaction network in embryonic stem cells.
van den Berg DL, Snoek T, Mullin NP, Yates A, Bezstarosti K, Demmers J, Chambers I, Poot RA
Cell Stem Cell. 2010
PubMed ID: 20362541
Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.
Li XS, Trojer P, Matsumura T, Treisman JE, Tanese N
Mol Cell Biol. 2010
PubMed ID: 20086098
CHD7 cooperates with PBAF to control multipotent neural crest formation.
Bajpai R, Chen DA, Rada-Iglesias A, Zhang J, Xiong Y, Helms J, Chang CP, Zhao Y, Swigut T, Wysocka J
Nature. 2010
PubMed ID: 20130577
The SWI/SNF chromatin-remodeling complex modulates peripheral T cell activation and proliferation by controlling AP-1 expression.
Jeong SM, Lee C, Lee SK, Kim J, Seong RH
J Biol Chem. 2010
PubMed ID: 19910461
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells.
Schaniel C, Ang YS, Ratnakumar K, Cormier C, James T, Bernstein E, Lemischka IR, Paddison PJ
Stem Cells. 2009
PubMed ID: 19785031
Variations in the composition of mammalian SWI/SNF chromatin remodelling complexes.
Ryme J, Asp P, Böhm S, Cavellán E, Farrants AK
J Cell Biochem. 2009
PubMed ID: 19650111
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.
Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD
J Neurosci. 2009
PubMed ID: 19741146
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
BRIT1/MCPH1 links chromatin remodelling to DNA damage response.
Peng G, Yim EK, Dai H, Jackson AP, Burgt I, Pan MR, Hu R, Li K, Lin SY
Nat Cell Biol. 2009
PubMed ID: 19525936
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.
Rambaud J, Desroches J, Balsalobre A, Drouin J
J Biol Chem. 2009
PubMed ID: 19321449
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ
Mol Cell Proteomics. 2009
PubMed ID: 19131326
A functional screen to identify novel effectors of hematopoietic stem cell activity.
Deneault E, Cellot S, Faubert A, Laverdure JP, Fréchette M, Chagraoui J, Mayotte N, Sauvageau M, Ting SB, Sauvageau G
Cell. 2009
PubMed ID: 19379700
Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.
So HC, Fong PY, Chen RY, Hui TC, Ng MY, Cherny SS, Mak WW, Cheung EF, Chan RC, Chen EY, Li T, Sham PC
Am J Med Genet B Neuropsychiatr Genet. 2009
PubMed ID: 19367581
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.
Ho L, Ronan JL, Wu J, Staahl BT, Chen L, Kuo A, Lessard J, Nesvizhskii AI, Ranish J, Crabtree GR
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19279220
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network.
Ho L, Jothi R, Ronan JL, Cui K, Zhao K, Crabtree GR
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19279218
Dysregulation of the transcription factors SOX4, CBFB and SMARCC1 correlates with outcome of colorectal cancer.
Andersen CL, Christensen LL, Thorsen K, Schepeler T, Sørensen FB, Verspaget HW, Simon R, Kruhøffer M, Aaltonen LA, Laurberg S, Ørntoft TF
Br J Cancer. 2009
PubMed ID: 19156145
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK
Sci Signal. 2009
PubMed ID: 19690332
The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity. 2009
PubMed ID: 19144319
Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.
Wang B, Malik R, Nigg EA, Körner R
Anal Chem. 2008
PubMed ID: 19007248
Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry.
Zanivan S, Gnad F, Wickström SA, Geiger T, Macek B, Cox J, Fässler R, Mann M
J Proteome Res. 2008
PubMed ID: 19367708
BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.
Kaeser MD, Aslanian A, Dong MQ, Yates JR, Emerson BM
J Biol Chem. 2008
PubMed ID: 18809673
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Lange M, Kaynak B, Forster UB, Tönjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S
Genes Dev. 2008
PubMed ID: 18765789
SMARCC1 expression is upregulated in prostate cancer and positively correlated with tumour recurrence and dedifferentiation.
Heebøll S, Borre M, Ottosen PD, Andersen CL, Mansilla F, Dyrskjøt L, Orntoft TF, Tørring N
Histol Histopathol. 2008
PubMed ID: 18581278
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb).
Ito T, Watanabe H, Yamamichi N, Kondo S, Tando T, Haraguchi T, Mizutani T, Sakurai K, Fujita S, Izumi T, Isobe T, Iba H
Biochem J. 2008
PubMed ID: 18042045
SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.
Han D, Jeon S, Sohn DH, Lee C, Ahn S, Kim WK, Chung H, Seong RH
Dev Biol. 2008
PubMed ID: 18206867
Toward a confocal subcellular atlas of the human proteome.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Mol Cell Proteomics. 2008
PubMed ID: 18029348
The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.
Trotter KW, Fan HY, Ivey ML, Kingston RE, Archer TK
Mol Cell Biol. 2008
PubMed ID: 18086889
Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.
Xi Q, He W, Zhang XH, Le HV, Massagué J
J Biol Chem. 2008
PubMed ID: 18003620
Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells.
Li H, Zhang Z, Wang B, Zhang J, Zhao Y, Jin Y
Mol Cell Biol. 2007
PubMed ID: 17526739
An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.
Holaska JM, Wilson KL
Biochemistry. 2007
PubMed ID: 17620012
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B
Mol Cell. 2007
PubMed ID: 17643375
An essential switch in subunit composition of a chromatin remodeling complex during neural development.
Lessard J, Wu JI, Ranish JA, Wan M, Winslow MM, Staahl BT, Wu H, Aebersold R, Graef IA, Crabtree GR
Neuron. 2007
PubMed ID: 17640523
Down-regulation of the SWI/SNF chromatin remodeling activity by TCR signaling is required for proper thymocyte maturation.
Lee KY, Choi YI, Kim J, Choi JW, Sohn DH, Lee C, Jeon SH, Seong RH
J Immunol. 2007
PubMed ID: 17513758
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.
Wu C, Ma MH, Brown KR, Geisler M, Li L, Tzeng E, Jia CY, Jurisica I, Li SS
Proteomics. 2007
PubMed ID: 17474147
SRG3 interacts directly with the major components of the SWI/SNF chromatin remodeling complex and protects them from proteasomal degradation.
Sohn DH, Lee KY, Lee C, Oh J, Chung H, Jeon SH, Seong RH
J Biol Chem. 2007
PubMed ID: 17255092
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.
Molina H, Horn DM, Tang N, Mathivanan S, Pandey A
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17287340
Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.
Nagl NG, Wang X, Patsialou A, Van Scoy M, Moran E
EMBO J. 2007
PubMed ID: 17255939
Large-scale phosphorylation analysis of mouse liver.
Villén J, Beausoleil SA, Gerber SA, Gygi SP
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17242355
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Koch HB, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates JR, Menssen A, Hermeking H
Cell Cycle. 2007
PubMed ID: 17314511
Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression.
Lee YS, Sohn DH, Han D, Lee HW, Seong RH, Kim JB
Mol Cell Biol. 2007
PubMed ID: 17074803
A protein interaction network for pluripotency of embryonic stem cells.
Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH
Nature. 2006
PubMed ID: 17093407
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.
Hu K, Nan X, Bird A, Wang W
Nat Genet. 2006
PubMed ID: 16940996
Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt.
Foster KS, McCrary WJ, Ross JS, Wright CF
Oncogene. 2006
PubMed ID: 16568092
Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ
Hum Mol Genet. 2006
PubMed ID: 16787967
Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.
He W, Dorn DC, Erdjument-Bromage H, Tempst P, Moore MA, Massagué J
Cell. 2006
PubMed ID: 16751102
The DNA sequence, annotation and analysis of human chromosome 3.
Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA
Nature. 2006
PubMed ID: 16641997
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter.
Tréand C, du Chéné I, Brès V, Kiernan R, Benarous R, Benkirane M, Emiliani S
EMBO J. 2006
PubMed ID: 16601680
Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.
Inayoshi Y, Miyake K, Machida Y, Kaneoka H, Terajima M, Dohda T, Takahashi M, Iijima S
J Biochem. 2006
PubMed ID: 16452305
ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.
Doyon Y, Cayrou C, Ullah M, Landry AJ, Côté V, Selleck W, Lane WS, Tan S, Yang XJ, Côté J
Mol Cell. 2006
PubMed ID: 16387653
Expression of SRG3, a core component of mouse SWI/SNF chromatin-remodeling complex, is regulated by cooperative interactions between Sp1/Sp3 and Ets transcription factors.
Ahn J, Ko M, Lee K, Oh J, Jeon SH, Seong RH
Biochem Biophys Res Commun. 2005
PubMed ID: 16288722
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.
McCracken S, Longman D, Marcon E, Moens P, Downey M, Nickerson JA, Jessberger R, Wilde A, Caceres JF, Emili A, Blencowe BJ
J Biol Chem. 2005
PubMed ID: 16159877
A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development.
Bultman SJ, Gebuhr TC, Magnuson T
Genes Dev. 2005
PubMed ID: 16287714
Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region.
Mahajan MC, Narlikar GJ, Boyapaty G, Kingston RE, Weissman SM
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16217013
The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.
Nagl NG, Patsialou A, Haines DS, Dallas PB, Beck GR, Moran E
Cancer Res. 2005
PubMed ID: 16230384
Regulating SWI/SNF subunit levels via protein-protein interactions and proteasomal degradation: BAF155 and BAF170 limit expression of BAF57.
Chen J, Archer TK
Mol Cell Biol. 2005
PubMed ID: 16199878
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
WW domains provide a platform for the assembly of multiprotein networks.
Ingham RJ, Colwill K, Howard C, Dettwiler S, Lim CS, Yu J, Hersi K, Raaijmakers J, Gish G, Mbamalu G, Taylor L, Yeung B, Vassilovski G, Amin M, Chen F, Matskova L, Winberg G, Ernberg I, Linding R, O'donnell P, Starostine A, Keller W, Metalnikov P, Stark C, Pawson T
Mol Cell Biol. 2005
PubMed ID: 16055720
PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.
Yan Z, Cui K, Murray DM, Ling C, Xue Y, Gerstein A, Parsons R, Zhao K, Wang W
Genes Dev. 2005
PubMed ID: 15985610
Global phosphoproteome of HT-29 human colon adenocarcinoma cells.
Kim JE, Tannenbaum SR, White FM
J Proteome Res. 2005
PubMed ID: 16083285
Modulation of androgen receptor transactivation by the SWI3-related gene product (SRG3) in multiple ways.
Hong CY, Suh JH, Kim K, Gong EY, Jeon SH, Ko M, Seong RH, Kwon HB, Lee K
Mol Cell Biol. 2005
PubMed ID: 15923603
Tagging genes with cassette-exchange sites.
Cobellis G, Nicolaus G, Iovino M, Romito A, Marra E, Barbarisi M, Sardiello M, Di Giorgio FP, Iovino N, Zollo M, Ballabio A, Cortese R
Nucleic Acids Res. 2005
PubMed ID: 15741177
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.
Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG
Nature. 2004
PubMed ID: 15525990
Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.
Wang X, Nagl NG, Wilsker D, Van Scoy M, Pacchione S, Yaciuk P, Dallas PB, Moran E
Biochem J. 2004
PubMed ID: 15170388
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP.
Kemper JK, Kim H, Miao J, Bhalla S, Bae Y
Mol Cell Biol. 2004
PubMed ID: 15314177
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15302935
Nitric oxide inhibits glucocorticoid-induced apoptosis of thymocytes by repressing the SRG3 expression.
Jeong SM, Lee KY, Shin D, Chung H, Jeon SH, Seong RH
J Biol Chem. 2004
PubMed ID: 15187086
E2A/HEB and Id3 proteins control the sensitivity to glucocorticoid-induced apoptosis in thymocytes by regulating the SRG3 expression.
Ko M, Ahn J, Lee C, Chung H, Jeon SH, Chung HY, Seong RH
J Biol Chem. 2004
PubMed ID: 15016815
T cell receptor signaling inhibits glucocorticoid-induced apoptosis by repressing the SRG3 expression via Ras activation.
Ko M, Jang J, Ahn J, Lee K, Chung H, Jeon SH, Seong RH
J Biol Chem. 2004
PubMed ID: 15016814
The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.
Medjkane S, Novikov E, Versteege I, Delattre O
Cancer Res. 2004
PubMed ID: 15150092
Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.
Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC
Anal Chem. 2004
PubMed ID: 15144186
Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells.
Wang Q, Udayakumar TS, Vasaitis TS, Brodie AM, Fondell JD
J Biol Chem. 2004
PubMed ID: 14966121
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.
Brajenovic M, Joberty G, Küster B, Bouwmeester T, Drewes G
J Biol Chem. 2004
PubMed ID: 14676191
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G
Nat Cell Biol. 2004
PubMed ID: 14743216
A methylation-mediator complex in hormone signaling.
Xu W, Cho H, Kadam S, Banayo EM, Anderson S, Yates JR, Emerson BM, Evans RM
Genes Dev. 2004
PubMed ID: 14729568
Protein profile of tax-associated complexes.
Wu K, Bottazzi ME, de la Fuente C, Deng L, Gitlin SD, Maddukuri A, Dadgar S, Li H, Vertes A, Pumfery A, Kashanchi F
J Biol Chem. 2004
PubMed ID: 14530271
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.
Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, Kumar J, Tempst P, Sif S
Mol Cell Biol. 2003
PubMed ID: 14559996
BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.
Hsiao PW, Fryer CJ, Trotter KW, Wang W, Archer TK
Mol Cell Biol. 2003
PubMed ID: 12917342
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.
Kitagawa H, Fujiki R, Yoshimura K, Mezaki Y, Uematsu Y, Matsui D, Ogawa S, Unno K, Okubo M, Tokita A, Nakagawa T, Ito T, Ishimi Y, Nagasawa H, Matsumoto T, Yanagisawa J, Kato S
Cell. 2003
PubMed ID: 12837248
Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.
Nie Z, Yan Z, Chen EH, Sechi S, Ling C, Zhou S, Xue Y, Yang D, Murray D, Kanakubo E, Cleary ML, Wang W
Mol Cell Biol. 2003
PubMed ID: 12665591
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.
Nakamura T, Mori T, Tada S, Krajewski W, Rozovskaia T, Wassell R, Dubois G, Mazo A, Croce CM, Canaani E
Mol Cell. 2002
PubMed ID: 12453419
Identification of a polymorphic, neuron-specific chromatin remodeling complex.
Olave I, Wang W, Xue Y, Kuo A, Crabtree GR
Genes Dev. 2002
PubMed ID: 12368262
Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.
Huang M, Qian F, Hu Y, Ang C, Li Z, Wen Z
Nat Cell Biol. 2002
PubMed ID: 12244326
SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription.
Lee D, Kim JW, Seo T, Hwang SG, Choi EJ, Choe J
J Biol Chem. 2002
PubMed ID: 11950834
SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.
Kato H, Tjernberg A, Zhang W, Krutchinsky AN, An W, Takeuchi T, Ohtsuki Y, Sugano S, de Bruijn DR, Chait BT, Roeder RG
J Biol Chem. 2002
PubMed ID: 11734557
Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).
Kuzmichev A, Zhang Y, Erdjument-Bromage H, Tempst P, Reinberg D
Mol Cell Biol. 2002
PubMed ID: 11784859
Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.
Otsuki T, Furukawa Y, Ikeda K, Endo H, Yamashita T, Shinohara A, Iwamatsu A, Ozawa K, Liu JM
Hum Mol Genet. 2001
PubMed ID: 11726552
Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development.
Kim JK, Huh SO, Choi H, Lee KS, Shin D, Lee C, Nam JS, Kim H, Chung H, Lee HW, Park SD, Seong RH
Mol Cell Biol. 2001
PubMed ID: 11604513
Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Piao Y, Ko NT, Lim MK, Ko MS
Genome Res. 2001
PubMed ID: 11544199
Notch1 confers a resistance to glucocorticoid-induced apoptosis on developing thymocytes by down-regulating SRG3 expression.
Choi YI, Jeon SH, Jang J, Han S, Kim JK, Chung H, Lee HW, Chung HY, Park SD, Seong RH
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11504912
Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.
Sif S, Saurin AJ, Imbalzano AN, Kingston RE
Genes Dev. 2001
PubMed ID: 11238380
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.
Underhill C, Qutob MS, Yee SP, Torchia J
J Biol Chem. 2000
PubMed ID: 11013263
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.
Xue Y, Canman JC, Lee CS, Nie Z, Yang D, Moreno GT, Young MK, Salmon ED, Wang W
Proc Natl Acad Sci U S A. 2000
PubMed ID: 11078522
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Functional selectivity of recombinant mammalian SWI/SNF subunits.
Kadam S, McAlpine GS, Phelan ML, Kingston RE, Jones KA, Emerson BM
Genes Dev. 2000
PubMed ID: 11018012
An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.
O'Neill DW, Schoetz SS, Lopez RA, Castle M, Rabinowitz L, Shor E, Krawchuk D, Goll MG, Renz M, Seelig HP, Han S, Seong RH, Park SD, Agalioti T, Munshi N, Thanos D, Erdjument-Bromage H, Tempst P, Bank A
Mol Cell Biol. 2000
PubMed ID: 11003653
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.
Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R
Cell. 2000
PubMed ID: 10943845
A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.
Kowenz-Leutz E, Leutz A
Mol Cell. 1999
PubMed ID: 10619021
Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.
Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K
Immunity. 1999
PubMed ID: 10204490
Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest.
Shanahan F, Seghezzi W, Parry D, Mahony D, Lees E
Mol Cell Biol. 1999
PubMed ID: 9891079
Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.
Phelan ML, Sif S, Narlikar GJ, Kingston RE
Mol Cell. 1999
PubMed ID: 10078207
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).
Reyes JC, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M
EMBO J. 1998
PubMed ID: 9843504
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling.
Zhao K, Wang W, Rando OJ, Xue Y, Swiderek K, Kuo A, Crabtree GR
Cell. 1998
PubMed ID: 9845365
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.
Sif S, Stukenberg PT, Kirschner MW, Kingston RE
Genes Dev. 1998
PubMed ID: 9744861
A human RNA polymerase II complex containing factors that modify chromatin structure.
Cho H, Orphanides G, Sun X, Yang XJ, Ogryzko V, Lees E, Nakatani Y, Reinberg D
Mol Cell Biol. 1998
PubMed ID: 9710619
Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome.
Ring HZ, Vameghi-Meyers V, Wang W, Crabtree GR, Francke U
Genomics. 1998
PubMed ID: 9693044
p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.
Dallas PB, Cheney IW, Liao DW, Bowrin V, Byam W, Pacchione S, Kobayashi R, Yaciuk P, Moran E
Mol Cell Biol. 1998
PubMed ID: 9584200
Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.
Fryer CJ, Archer TK
Nature. 1998
PubMed ID: 9590696
A new mouse gene, SRG3, related to the SWI3 of Saccharomyces cerevisiae, is required for apoptosis induced by glucocorticoids in a thymoma cell line.
Jeon SH, Kang MG, Kim YH, Jin YH, Lee C, Chung HY, Kwon H, Park SD, Seong RH
J Exp Med. 1997
PubMed ID: 9151708
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
Wang W, Côté J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL, Crabtree GR
EMBO J. 1996
PubMed ID: 8895581
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Diversity and specialization of mammalian SWI/SNF complexes.
Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR
Genes Dev. 1996
PubMed ID: 8804307

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	Human	Mouse	Rat
Entrez Gene	6599	20588	301020
EnsEMBL Gene(s)	ENSG00000173473	ENSMUSG00000032481	ENSRNOG00000020804
Unigene	Hs.476179	Mm.85410	Rn.94211
Homologene	SMARCC1	Smarcc1	Smarcc1
OMIM	601732	N/A	N/A
GeneCards	SMARCC1	N/A	N/A
Beta Cell Genomics	DT.95129928 DT.95201837	DT.101253562 DT.101381809 DT.101381810 DT.101381811 DT.101381812 DT.101738711 DT.110600972 DT.486418 DT.55247499 DT.91336209	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	6599	20588	301020

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Interactor	Interactor	Sources	Classification	Pubmed IDs
SMARCC1	ALL1	BioGRID	empirical	12453419
SMARCC1	TRIM28	BioGRID	empirical	20508149
SMARCC1	CDK8	BioGRID	empirical	9710619
SMARCC1	SF3A1	Sanger Interaction Map	predicted	15345047
SMARCC1	IKZF1	BioGRID	empirical	10204490
SMARCC1	PRMT5	BioGRID	empirical	14559996
SMARCC1	CARM1	BioGRID	empirical	14729568
SMARCC1	CEBPB	HPRD	empirical	10619021
SMARCC1	KLF1	HPRD, BioGRID	empirical	11018012
SMARCC1	WWP2	BioGRID	empirical	17526739
SMARCC1	CHD4	BioGRID	empirical	16217013 11003653
SMARCC1	NACC1	BioGRID	empirical	17093407
SMARCC1	GABARAPL2	IntAct	empirical	20562859
SMARCC1	ADD1	BioGRID	empirical	17074803
SMARCC1	ZFP42	BioGRID	empirical	17093407
SMARCC1	CREBBP	BioGRID	empirical	9584200
SMARCC1	ARID2	IntAct, BioGRID	empirical	15985610
SMARCC1	EMD	BioGRID	empirical	17620012
SMARCC1	AKT1	BioGRID	empirical	16568092
SMARCC1	ESRRB	BioGRID	empirical	20362541
SMARCC1	EYA3	Sanger Interaction Map	predicted	15345047
SMARCC1	FANCA	HPRD	empirical	11726552
SMARCC1	KDM6B	BioGRID	empirical	21095589
SMARCC1	SCRIB	Sanger Interaction Map	predicted	15345047
SMARCC1	SRRM2	BioGRID	empirical	16159877
SMARCC1	SIN3A	HPRD, BioGRID	empirical	11238380 11784859 12453419
SMARCC1	GATA1	BioGRID	empirical	11018012
SMARCC1	GRB2	IntAct	empirical	17474147
SMARCC1	NR3C1	HPRD, IntAct, BioGRID	empirical	9590696 12917342
SMARCC1	BRD7	BioGRID	empirical	18809673
SMARCC1	TFCP2L1	BioGRID	empirical	20362541
SMARCC1	HDAC2	IntAct	empirical	15696166
SMARCC1	NR4A1	BioGRID	empirical	19321449
SMARCC1	IKBKB	MINT, IntAct	empirical	14743216
SMARCC1	ING1	BioGRID	empirical	11784859
SMARCC1	ING2	BioGRID	empirical	16387653
SMARCC1	AR	BioGRID	empirical	15923603
SMARCC1	ARF6	IntAct	empirical	17353931
SMARCC1	SMAD2	IntAct, BioGRID	empirical	20195357 18003620 16751102
SMARCC1	SMAD3	BioGRID	empirical	18003620
SMARCC1	MYC	IntAct, BioGRID	empirical	17353931 17314511 14559996
SMARCC1	NONO	BioGRID	empirical	18042045
SMARCC1	METTL13	Sanger Interaction Map	predicted	15345047
SMARCC1	WWOX	MINT	empirical	16055720
SMARCC1	POU5F1	IntAct, BioGRID	empirical	20362542 20362541
SMARCC1	WHSC1L1	BioGRID	empirical	21555454
SMARCC1	PBRM1	BioGRID	empirical	19650111 15985610
SMARCC1	CHD7	BioGRID	empirical	20130577
SMARCC1	SMARCAD1	BioGRID	empirical	21549307
SMARCC1	SALL4	BioGRID	empirical	20362541
SMARCC1	ARID1B	MINT, BioGRID	empirical	17255939 20086098 16230384 15170388 21118156
SMARCC1	PTPN11	IntAct	empirical	15102471
SMARCC1	RELB	HPRD, MINT, IntAct, BioGRID	empirical	14743216
SMARCC1	DPF2	BioGRID	empirical	20460684 20400511
SMARCC1	SMARCA2	BioGRID	empirical	11238380 8895581 16940996 19279220 16452305 14559996 16230384 12453419 20460684
SMARCC1	SMARCA4	HPRD, IntAct, BioGRID	empirical	9891079 12917342 18303029 17255092 10078207 12368262 15985610 11238380 8895581 11726552 9845365 18809673 19279220 16452305 14559996 16287714 16230384 16217013 18086889 9584200 20460684 21520050
SMARCC1	SMARCB1	IntAct, BioGRID	empirical	17255092 10078207 11238380 8895581 19650111 18809673 16568092 15150092 9744861 9584200 21520050
SMARCC1	SMARCC1	BioGRID	empirical	16230384
SMARCC1	SMARCC2	BioGRID	empirical	19650111 18809673 16230384
SMARCC1	SMARCD1	IntAct, BioGRID	empirical	12917342 18303029 17255092
SMARCC1	SMARCD3	HPRD	empirical	9891079
SMARCC1	SMARCE1	IntAct, BioGRID	empirical	17255092 9845365 16940996 19650111 18809673 16199878 20829358
SMARCC1	SOX2	BioGRID	empirical	21532573
SMARCC1	SP1	BioGRID	empirical	11018012
SMARCC1	SRC	BioGRID	empirical	15923603
SMARCC1	BRCA1	BioGRID	empirical	10943845
SMARCC1	STAT2	BioGRID	empirical	12244326
SMARCC1	STK11	IntAct, BioGRID	empirical	14676191
SMARCC1	TAF6	BioGRID	empirical	12453419
SMARCC1	TAF10	BioGRID	empirical	17643375
SMARCC1	TAT	BioGRID	empirical	16601680
SMARCC1	TP53	IntAct, BioGRID	empirical	18303029 11950834
SMARCC1	HSP90B1	BioGRID	empirical	11726552
SMARCC1	UBC	BioGRID	empirical	18781797 20972266 21890473 21906983
SMARCC1	VHL	IntAct	empirical	17353931
SMARCC1	MCPH1	BioGRID	empirical	19525936
SMARCC1	ARID1A	MINT, BioGRID	empirical	17255939 19650111 16230384 15170388
SMARCC1	ITCH	BioGRID	empirical	16055720
SMARCC1	NR0B2	BioGRID	empirical	15314177
SMARCC1	KHSRP	Sanger Interaction Map	predicted	15345047
SMARCC1	ACTL6A	IntAct	empirical	11780067
SMARCC1	RUNX1	BioGRID	empirical	20506188
SMARCC1	CCNE1	HPRD, BioGRID	empirical	9891079
SMARCC1	BAZ1B	BioGRID	empirical	12837248
SMARCC1	BCL7C	BioGRID	empirical	18809673
SMARCC1	BCL7B	BioGRID	empirical	20360068
SMARCC1	NCOR1	IntAct, BioGRID	empirical	11013263
SMARCC1	IKBKE	IntAct	empirical	17353931
SMARCC1	KIAA0101	BioGRID	empirical	21628590