SMARCA4
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(Human) GRCh37 - chr19:11071598..11172958 (101.36 kb) View in Genome Browser
(Mouse) NCBIM37 - chr9:21420613..21508674 (886 kb) View in Genome Browser
(Rat) RGSC3.4 - chr8:20720915..20812157 (91.24 kb) View in Genome Browser
HaemAtlas Expression Table for SMARCA4:
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
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| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
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Expression Legend
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for SMARCA4:The SMARCA4 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| SMARCA4 | TRIM28 | BioGRID | empirical | 20508149 |
| SMARCA4 | MPHOSPH6 | HPRD, IntAct | empirical | 15231747 |
| SMARCA4 | CDKN2A | BioGRID | empirical | 19149898 |
| SMARCA4 | IKZF1 | HPRD, IntAct, BioGRID | empirical | 10204490 15767674 |
| SMARCA4 | PRMT5 | IntAct, BioGRID | empirical | 20951943 17043109 14559996 |
| SMARCA4 | CDX2 | BioGRID | empirical | 19371634 20485553 |
| SMARCA4 | CARM1 | BioGRID | empirical | 14729568 |
| SMARCA4 | CEBPA | BioGRID | empirical | 16452305 |
| SMARCA4 | CEBPB | HPRD | empirical | 10619021 |
| SMARCA4 | MYBBP1A | BioGRID | empirical | 19279220 |
| SMARCA4 | KLF1 | BioGRID | empirical | 11018012 |
| SMARCA4 | ZMYND11 | HPRD | empirical | 16565076 |
| SMARCA4 | CBX1 | IntAct | empirical | 21888893 |
| SMARCA4 | TOPBP1 | BioGRID | empirical | 20571081 |
| SMARCA4 | CHD4 | HPRD, BioGRID | empirical | 14530259 16217013 11003653 |
| SMARCA4 | CBX3 | IntAct | empirical | 21888893 |
| SMARCA4 | GABARAPL2 | IntAct | empirical | 20562859 |
| SMARCA4 | ADD1 | BioGRID | empirical | 17074803 |
| SMARCA4 | CREB1 | HPRD, MINT, BioGRID | empirical | 16675956 |
| SMARCA4 | CREBBP | BioGRID | empirical | 11003650 9443979 9584200 |
| SMARCA4 | NKX2-5 | BioGRID | empirical | 15525990 |
| SMARCA4 | CTNNB1 | HPRD, BioGRID | empirical | 11532957 15525990 |
| SMARCA4 | DDX5 | BioGRID | empirical | 17011493 |
| SMARCA4 | DNMT3A | BioGRID | empirical | 16322236 |
| SMARCA4 | AHR | HPRD, BioGRID | empirical | 11805098 |
| SMARCA4 | ARID2 | HPRD, IntAct, BioGRID | empirical | 15985610 19279220 |
| SMARCA4 | ESR1 | HPRD, MINT, BioGRID | empirical | 9099865 18451880 11003650 |
| SMARCA4 | ESRRB | BioGRID | empirical | 20362541 |
| SMARCA4 | ETS2 | HPRD, BioGRID | empirical | 12637547 |
| SMARCA4 | FANCA | HPRD, MINT | empirical | 11726552 |
| SMARCA4 | KDM4B | BioGRID | empirical | 21445275 |
| SMARCA4 | KDM4C | BioGRID | empirical | 21445275 |
| SMARCA4 | KDM6B | BioGRID | empirical | 21095589 |
| SMARCA4 | RCOR1 | IntAct, BioGRID | empirical | 12192000 |
| SMARCA4 | SIN3B | BioGRID | empirical | 14559996 |
| SMARCA4 | ADNP | BioGRID | empirical | 17878164 |
| SMARCA4 | CBX5 | HPRD, IntAct, BioGRID | empirical | 12411497 20562864 15882967 20011120 |
| SMARCA4 | BRD4 | BioGRID | empirical | 21555454 |
| SMARCA4 | SRRM2 | BioGRID | empirical | 19279220 |
| SMARCA4 | ZMYND8 | BioGRID | empirical | 16565076 |
| SMARCA4 | SIN3A | BioGRID | empirical | 11238380 11784859 19081374 16800816 14559996 |
| SMARCA4 | SS18L1 | BioGRID | empirical | 19081374 19279220 |
| SMARCA4 | GATA1 | BioGRID | empirical | 11018012 |
| SMARCA4 | GATA4 | BioGRID | empirical | 15525990 |
| SMARCA4 | NR3C1 | HPRD, IntAct, BioGRID | empirical | 9590696 12917342 10688647 9128241 17387179 |
| SMARCA4 | BRD7 | BioGRID | empirical | 18809673 19279220 |
| SMARCA4 | TFCP2L1 | BioGRID | empirical | 20362541 |
| SMARCA4 | GLTSCR1 | BioGRID | empirical | 19279220 |
| SMARCA4 | TBX21 | BioGRID | empirical | 21095589 |
| SMARCA4 | H2AFX | BioGRID | empirical | 16932743 20224553 |
| SMARCA4 | H3F3A | HPRD | empirical | 15616580 |
| SMARCA4 | HDAC1 | IntAct, BioGRID | empirical | 12192000 19081374 20596014 |
| SMARCA4 | HDAC2 | IntAct, BioGRID | empirical | 12192000 11238380 19081374 16800816 14559996 20460684 20596014 |
| SMARCA4 | HIF1A | BioGRID | empirical | 15347669 |
| SMARCA4 | HSF1 | HPRD, BioGRID | empirical | 11486022 9222609 8856972 20353823 21079652 |
| SMARCA4 | HSF4 | BioGRID | empirical | 16552721 |
| SMARCA4 | ING1 | BioGRID | empirical | 11784859 |
| SMARCA4 | IRF1 | BioGRID | empirical | 16195385 |
| SMARCA4 | JUNB | BioGRID | empirical | 9128241 14673171 |
| SMARCA4 | KPNA2 | BioGRID | empirical | 20460684 |
| SMARCA4 | LMNB1 | BioGRID | empirical | 9128241 |
| SMARCA4 | SMAD2 | BioGRID | empirical | 18003620 16751102 |
| SMARCA4 | SMAD3 | BioGRID | empirical | 18003620 |
| SMARCA4 | MEF2A | MINT | empirical | 16424906 |
| SMARCA4 | CIITA | BioGRID | empirical | 12077331 |
| SMARCA4 | MYC | IntAct, BioGRID | empirical | 17353931 11839798 14559996 |
| SMARCA4 | MYOD1 | BioGRID | empirical | 20195544 15870273 |
| SMARCA4 | MYOG | MINT, BioGRID | empirical | 16424906 |
| SMARCA4 | ATF3 | BioGRID | empirical | 14673171 |
| SMARCA4 | NEUROD1 | BioGRID | empirical | 16024661 |
| SMARCA4 | NF1 | BioGRID | empirical | 15999204 |
| SMARCA4 | NFE2L2 | BioGRID | empirical | 16923960 |
| SMARCA4 | NFKB2 | MINT | empirical | 14743216 |
| SMARCA4 | NONO | BioGRID | empirical | 19279220 18042045 20460684 |
| SMARCA4 | NPM1 | BioGRID | empirical | 20460684 |
| SMARCA4 | NUMA1 | BioGRID | empirical | 19279220 |
| SMARCA4 | PAX6 | HPRD, MINT | empirical | 16675956 |
| SMARCA4 | MYEF2 | BioGRID | empirical | 16424906 15870273 |
| SMARCA4 | PBX1 | BioGRID | empirical | 15870273 |
| SMARCA4 | PCNA | BioGRID | empirical | 9443979 |
| SMARCA4 | ACTL6B | BioGRID | empirical | 12368262 |
| SMARCA4 | CHMP5 | HPRD | empirical | 16730941 |
| SMARCA4 | TRIM33 | IntAct | empirical | 20603019 |
| SMARCA4 | MPP6 | HPRD, BioGRID | empirical | 15231747 |
| SMARCA4 | PHB | HPRD, BioGRID | empirical | 12065415 15141164 |
| SMARCA4 | MBD3 | BioGRID | empirical | 16322236 22196727 |
| SMARCA4 | PML | BioGRID | empirical | 21360626 |
| SMARCA4 | BRWD1 | HPRD, IntAct, BioGRID | empirical | 12889071 |
| SMARCA4 | POLR2A | BioGRID | empirical | 11238380 8895581 9845365 9128241 16195385 15999204 |
| SMARCA4 | POU5F1 | IntAct, BioGRID | empirical | 20362542 20362541 |
| SMARCA4 | PPARG | IntAct | empirical | 14701856 |
| SMARCA4 | WHSC1L1 | BioGRID | empirical | 21555454 |
| SMARCA4 | PBRM1 | HPRD, IntAct, BioGRID | empirical | 12368262 15985610 11780067 19279220 |
| SMARCA4 | PHF10 | BioGRID | empirical | 19279220 |
| SMARCA4 | CHD7 | BioGRID | empirical | 20130577 21532573 |
| SMARCA4 | SMARCAD1 | BioGRID | empirical | 21549307 |
| SMARCA4 | SALL4 | BioGRID | empirical | 20362541 |
| SMARCA4 | ARID1B | HPRD, MINT, IntAct, BioGRID | empirical | 11988099 12200431 17255939 19279220 20086098 15170388 21118156 |
| SMARCA4 | MARK4 | IntAct, BioGRID | empirical | 14676191 |
| SMARCA4 | RAP1A | HPRD | empirical | 15207703 |
| SMARCA4 | RB1 | HPRD, IntAct, BioGRID | empirical | 7923370 12434308 9128241 19081374 15485920 10778858 17666433 |
| SMARCA4 | RBBP4 | BioGRID | empirical | 11238380 |
| SMARCA4 | RBL1 | IntAct | empirical | 12434308 |
| SMARCA4 | RBL2 | IntAct | empirical | 12434308 |
| SMARCA4 | RELB | HPRD, MINT, IntAct, BioGRID | empirical | 14743216 |
| SMARCA4 | DPF2 | BioGRID | empirical | 19279220 20460684 |
| SMARCA4 | REST | IntAct, BioGRID | empirical | 12192000 17023429 |
| SMARCA4 | RFC1 | BioGRID | empirical | 9443979 |
| SMARCA4 | RFXAP | HPRD | empirical | 15781111 |
| SMARCA4 | ACTB | HPRD, IntAct, BioGRID | empirical | 9845365 15985610 |
| SMARCA4 | BCL7A | BioGRID | empirical | 19279220 20460684 |
| SMARCA4 | RPA1 | BioGRID | empirical | 9443979 |
| SMARCA4 | RXRA | BioGRID | empirical | 15774904 |
| SMARCA4 | UBE2O | IntAct | empirical | 19549727 |
| SMARCA4 | NEUROG2 | BioGRID | empirical | 16024661 |
| SMARCA4 | SFPQ | BioGRID | empirical | 19279220 |
| SMARCA4 | SMARCA2 | BioGRID | empirical | 9128241 19279220 14559996 18042045 |
| SMARCA4 | SMARCA4 | IntAct, BioGRID | empirical | 12917342 12368262 |
| SMARCA4 | SMARCB1 | HPRD, IntAct, BioGRID | empirical | 8895581 10078207 12368262 15985610 11238380 11486022 11726552 9845365 9128241 18809673 19279220 14559996 16287714 18414052 15150092 18042045 9744861 9584200 20460684 20506188 16687403 21520050 |
| SMARCA4 | BRD9 | BioGRID | empirical | 19279220 |
| SMARCA4 | SMARCC1 | HPRD, IntAct, BioGRID | empirical | 9891079 12917342 18303029 17255092 10078207 12368262 15985610 11238380 8895581 11726552 9845365 18809673 19279220 16452305 14559996 16287714 16230384 16217013 18086889 9584200 20460684 21520050 |
| SMARCA4 | SMARCC2 | IntAct, BioGRID | empirical | 10078207 12368262 15985610 8895581 11726552 9845365 18809673 19279220 14559996 18086889 20460684 |
| SMARCA4 | SMARCD1 | IntAct, BioGRID | empirical | 12917342 18303029 15985610 19279220 14559996 18042045 20460684 |
| SMARCA4 | SMARCD2 | IntAct, BioGRID | empirical | 12368262 14559996 |
| SMARCA4 | SMARCD3 | BioGRID | empirical | 19279220 |
| SMARCA4 | SMARCE1 | HPRD, IntAct, BioGRID | empirical | 12192000 12368262 8895581 9845365 16940996 18809673 19279220 14559996 16287714 11003653 20460684 19781646 |
| SMARCA4 | SP1 | IntAct, BioGRID | empirical | 20969766 11018012 12192045 15317818 |
| SMARCA4 | BRCA1 | HPRD, BioGRID | empirical | 10943845 15034933 |
| SMARCA4 | SRF | BioGRID | empirical | 19342595 17599918 |
| SMARCA4 | SS18 | HPRD | empirical | 14603256 |
| SMARCA4 | STAT1 | BioGRID | empirical | 16195385 20353823 21079652 |
| SMARCA4 | STAT2 | HPRD, BioGRID | empirical | 12244326 |
| SMARCA4 | STAT3 | BioGRID | empirical | 15286705 |
| SMARCA4 | STAT5A | BioGRID | empirical | 17387179 |
| SMARCA4 | STAT6 | BioGRID | empirical | 21262765 |
| SMARCA4 | STK11 | HPRD, IntAct, BioGRID | empirical | 11445556 14676191 |
| SMARCA4 | TAF9 | IntAct | empirical | 20195357 |
| SMARCA4 | TAF10 | BioGRID | empirical | 17643375 |
| SMARCA4 | TBX5 | BioGRID | empirical | 15525990 |
| SMARCA4 | TCF3 | BioGRID | empirical | 16252006 |
| SMARCA4 | ZEB1 | BioGRID | empirical | 20418909 |
| SMARCA4 | NKX2-1 | BioGRID | empirical | 19906647 |
| SMARCA4 | ACTG1 | BioGRID | empirical | 19279220 |
| SMARCA4 | TMF1 | HPRD | empirical | 12044884 |
| SMARCA4 | TP53 | HPRD, IntAct, BioGRID | empirical | 11950834 18303029 17666433 |
| SMARCA4 | HSP90B1 | BioGRID | empirical | 11726552 |
| SMARCA4 | UBC | BioGRID | empirical | 21139048 21890473 21906983 |
| SMARCA4 | NR1H2 | BioGRID | empirical | 15774904 |
| SMARCA4 | USF1 | BioGRID | empirical | 16195385 |
| SMARCA4 | KDM6A | BioGRID | empirical | 21095589 |
| SMARCA4 | VDR | BioGRID | empirical | 12837248 16252006 |
| SMARCA4 | YY1 | BioGRID | empirical | 21149256 |
| SMARCA4 | WDR77 | IntAct, BioGRID | empirical | 20951943 |
| SMARCA4 | MCPH1 | BioGRID | empirical | 19525936 |
| SMARCA4 | NANOG | BioGRID | empirical | 18454139 |
| SMARCA4 | PABPN1 | BioGRID | empirical | 11371506 |
| SMARCA4 | ARID1A | HPRD, MINT, IntAct, BioGRID | empirical | 11988099 17255939 12368262 15985610 11780067 12200431 8895581 9845365 19279220 14559996 16287714 15170388 18086889 20460684 |
| SMARCA4 | HIST1H3A | BioGRID | empirical | 20011120 15616580 |
| SMARCA4 | ZMIZ2 | BioGRID | empirical | 16051670 |
| SMARCA4 | SMARCA5 | Sanger Interaction Map | predicted | 15345047 |
| SMARCA4 | ACTL6A | HPRD, IntAct, BioGRID | empirical | 9845365 15985610 11780067 8895581 19279220 14559996 20460684 |
| SMARCA4 | RUNX1 | BioGRID | empirical | 20506188 |
| SMARCA4 | NCOA1 | BioGRID | empirical | 11003650 |
| SMARCA4 | HDAC3 | BioGRID | empirical | 19081374 |
| SMARCA4 | CCNE1 | HPRD, BioGRID | empirical | 9891079 11085541 |
| SMARCA4 | BAZ1B | BioGRID | empirical | 16252006 |
| SMARCA4 | BTAF1 | Sanger Interaction Map | predicted | 15345047 |
| SMARCA4 | BCL7C | BioGRID | empirical | 18809673 |
| SMARCA4 | BCL7B | IntAct, BioGRID | empirical | 20360068 |
| SMARCA4 | MYOCD | BioGRID | empirical | 19342595 |
| SMARCA4 | CDYL | BioGRID | empirical | 19061646 |
| SMARCA4 | MED17 | BioGRID | empirical | 12154023 |
| SMARCA4 | NCOR1 | IntAct, BioGRID | empirical | 11013263 |
| SMARCA4 | IKBKE | IntAct | empirical | 17353931 |
| SMARCA4 | KDM4A | BioGRID | empirical | 21445275 |
| SMARCA4 | KIAA0101 | BioGRID | empirical | 21628590 |
| SMARCA4 | SRGAP3 | IntAct | empirical | 12368262 |
| SMARCA4 | NR1H4 | BioGRID | empirical | 19805516 |
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Type 1 Diabetes Publications: 1
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Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development.
Anderson KR, White P, Kaestner KH, Sussel L
BMC Dev Biol. 2009
PubMed ID: 20003319
Publications: 347
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ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers.
Guan B, Wang TL, Shih IeM
Cancer Res. 2011
PubMed ID: 21900401
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Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1.
Hu G, Schones DE, Cui K, Ybarra R, Northrup D, Tang Q, Gattinoni L, Restifo NP, Huang S, Zhao K
Genome Res. 2011
PubMed ID: 21795385
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NF-κB and BRG1 bind a distal regulatory element in the IL-3/GM-CSF locus.
Wurster AL, Precht P, Pazin MJ
Mol Immunol. 2011
PubMed ID: 21831442
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Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development.
Zhan X, Shi X, Zhang Z, Chen Y, Wu JI
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21768360
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esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function.
Ho L, Miller EL, Ronan JL, Ho WQ, Jothi R, Crabtree GR
Nat Cell Biol. 2011
PubMed ID: 21785422
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BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest.
Bartlett C, Orvis TJ, Rosson GS, Weissman BE
J Cell Physiol. 2011
PubMed ID: 21520050
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BRG1 is indispensable for IFN-γ-induced TRIM22 expression, which is dependent on the recruitment of IRF-1.
Wang Y, Gao B, Xu W, Xiong S
Biochem Biophys Res Commun. 2011
PubMed ID: 21683060
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The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
Warnatz HJ, Schmidt D, Manke T, Piccini I, Sultan M, Borodina T, Balzereit D, Wruck W, Soldatov A, Vingron M, Lehrach H, Yaspo ML
J Biol Chem. 2011
PubMed ID: 21555518
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SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.
Zhang M, Chen M, Kim JR, Zhou J, Jones RE, Tune JD, Kassab GS, Metzger D, Ahlfeld S, Conway SJ, Herring BP
Mol Cell Biol. 2011
PubMed ID: 21518954
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MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4.
Schramedei K, Mörbt N, Pfeifer G, Läuter J, Rosolowski M, Tomm JM, von Bergen M, Horn F, Brocke-Heidrich K
Oncogene. 2011
PubMed ID: 21317927
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Cardiac genes show contextual SWI/SNF interactions with distinguishable gene activities.
Chang L, Kiriazis H, Gao XM, Du XJ, El-Osta A
Epigenetics. 2011
PubMed ID: 21586902
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Promyelocytic leukemia protein in retinoic acid-induced chromatin remodeling of Oct4 gene promoter.
Chuang YS, Huang WH, Park SW, Persaud SD, Hung CH, Ho PC, Wei LN
Stem Cells. 2011
PubMed ID: 21360626
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Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements.
De S, Wurster AL, Precht P, Wood WH, Becker KG, Pazin MJ
Mol Cell Biol. 2011
PubMed ID: 21262765
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Constitutive expression of the brg1 gene requires GC-boxes near to the transcriptional start site.
Itoh T, Miyake K, Yamaguchi T, Tsuge M, Kaneoka H, Iijima S
J Biochem. 2011
PubMed ID: 21149256
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Target genes of the largest human SWI/SNF complex subunit control cell growth.
Inoue H, Giannakopoulos S, Parkhurst CN, Matsumura T, Kono EA, Furukawa T, Tanese N
Biochem J. 2011
PubMed ID: 21118156
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The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels.
Griffin CT, Curtis CD, Davis RB, Muthukumar V, Magnuson T
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21262838
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Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells.
Watanabe T, Semba S, Yokozaki H
Br J Cancer. 2011
PubMed ID: 21102582
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Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.
Kawazu M, Saso K, Tong KI, McQuire T, Goto K, Son DO, Wakeham A, Miyagishi M, Mak TW, Okada H
PLoS One. 2011
PubMed ID: 21445275
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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
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Mol Cell. 2010
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BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.
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The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes.
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Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.
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The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways.
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Oncogene. 2010
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BRG1 helps RNA polymerase II to overcome a nucleosomal barrier during elongation, in vivo.
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Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
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Diabetes Care. 2010
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Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile.
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Blood. 2010
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BRG1 expression is increased in human cutaneous melanoma.
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Stat1 mediates an auto-regulation of hsp90beta gene in heat shock response.
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Cell Signal. 2010
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Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.
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Chromatin regulation by Brg1 underlies heart muscle development and disease.
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Nature. 2010
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Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function.
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Mol Cell Biol. 2010
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ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.
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Oncogene. 2010
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TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner.
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Proc Natl Acad Sci U S A. 2010
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SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.
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J Cell Physiol. 2010
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Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes.
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Systematic analysis of human protein complexes identifies chromosome segregation proteins.
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A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair.
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An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.
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Cell Stem Cell. 2010
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An Oct4-centered protein interaction network in embryonic stem cells.
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Cell Stem Cell. 2010
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Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance.
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Genome Res. 2010
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Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.
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Mol Cell Biol. 2010
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CHD7 cooperates with PBAF to control multipotent neural crest formation.
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Nature. 2010
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Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome.
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Am J Hum Genet. 2010
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Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene.
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J Biol Chem. 2010
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Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.
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Oncogene. 2010
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Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.
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Epigenetics Chromatin. 2010
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Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness.
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Mol Cancer. 2010
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Brg1 is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts.
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The core binding factor CBF negatively regulates skeletal muscle terminal differentiation.
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PLoS One. 2010
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Neuregulin-1 modulates the differentiation of neural stem cells in vitro through an interaction with the Swi/Snf complex.
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Mol Cell Neurosci. 2010
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A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
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Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression.
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PLoS Genet. 2009
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The chromatin remodeling factor BRG1 stimulates nucleotide excision repair by facilitating recruitment of XPC to sites of DNA damage.
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Cell Cycle. 2009
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Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.
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Mol Cell Biol. 2009
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Catalytic activity of the proteasome fine-tunes Brg1-mediated chromatin remodeling to regulate the expression of inflammatory genes.
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Mol Immunol. 2009
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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
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Am J Hum Genet. 2009
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Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.
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BRG1 directly regulates nucleosome structure and chromatin looping of the alpha globin locus to activate transcription.
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Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.
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Lysine acetylation targets protein complexes and co-regulates major cellular functions.
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BRG1 increases transcription of proinflammatory genes in renal ischemia.
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J Am Soc Nephrol. 2009
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The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.
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Oncogene. 2009
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Telomerase modulates Wnt signalling by association with target gene chromatin.
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BRIT1/MCPH1 links chromatin remodelling to DNA damage response.
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Nat Cell Biol. 2009
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SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.
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Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.
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J Cell Physiol. 2009
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Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells.
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Exp Cell Res. 2009
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Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF).
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Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
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Anal Chem. 2009
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The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.
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Arterioscler Thromb Vasc Biol. 2009
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Erythroid Kruppel-like factor (EKLF) is recruited to the gamma-globin gene promoter as a co-activator and is required for gamma-globin gene induction by short-chain fatty acid derivatives.
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Eur J Haematol. 2009
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Lineage-specific biology revealed by a finished genome assembly of the mouse.
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PLoS Biol. 2009
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An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.
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An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network.
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Proc Natl Acad Sci U S A. 2009
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Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
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Nat Genet. 2009
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BRG1 requirement for long-range interaction of a locus control region with a downstream promoter.
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Proc Natl Acad Sci U S A. 2009
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Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex.
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Eur J Immunol. 2009
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Stem Cells. 2009
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Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
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Sci Signal. 2009
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In vitro nuclear interactome of the HIV-1 Tat protein.
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Retrovirology. 2009
PubMed ID: 19454010
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Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.
Haiman CA, Garcia RR, Hsu C, Xia L, Ha H, Sheng X, Le Marchand L, Kolonel LN, Henderson BE, Stallcup MR, Greene GL, Press MF
BMC Cancer. 2009
PubMed ID: 19183483
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The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a.
Becker TM, Haferkamp S, Dijkstra MK, Scurr LL, Frausto M, Diefenbach E, Scolyer RA, Reisman DN, Mann GJ, Kefford RF, Rizos H
Mol Cancer. 2009
PubMed ID: 19149898
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The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity. 2009
PubMed ID: 19144319
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The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia.
Pottier N, Yang W, Assem M, Panetta JC, Pei D, Paugh SW, Cheng C, Den Boer ML, Relling MV, Pieters R, Evans WE, Cheok MH
J Natl Cancer Inst. 2008
PubMed ID: 19066270
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A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.
Qiu Z, Ghosh A
Neuron. 2008
PubMed ID: 19081374
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CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y
Mol Cell. 2008
PubMed ID: 19061646
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Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry.
Zanivan S, Gnad F, Wickström SA, Geiger T, Macek B, Cox J, Fässler R, Mann M
J Proteome Res. 2008
PubMed ID: 19367708
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BRG1-mediated chromatin remodeling regulates differentiation and gene expression of T helper cells.
Wurster AL, Pazin MJ
Mol Cell Biol. 2008
PubMed ID: 18852284
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A novel genetic strategy reveals unexpected roles of the Swi-Snf-like chromatin-remodeling BAF complex in thymocyte development.
Jani A, Wan M, Zhang J, Cui K, Wu J, Preston-Hurlburt P, Khatri R, Zhao K, Chi T
J Exp Med. 2008
PubMed ID: 18955569
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BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.
Kaeser MD, Aslanian A, Dong MQ, Yates JR, Emerson BM
J Biol Chem. 2008
PubMed ID: 18809673
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Baf60c is a component of the neural progenitor-specific BAF complex in developing retina.
Lamba DA, Hayes S, Karl MO, Reh T
Dev Dyn. 2008
PubMed ID: 18816825
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
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Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Lange M, Kaynak B, Forster UB, Tönjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S
Genes Dev. 2008
PubMed ID: 18765789
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Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.
Dai Y, Ngo D, Jacob J, Forman LW, Faller DV
Carcinogenesis. 2008
PubMed ID: 18487222
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A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
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Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.
Johnson TA, Elbi C, Parekh BS, Hager GL, John S
Mol Biol Cell. 2008
PubMed ID: 18508913
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Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
Lu Y, Dollé ME, Imholz S, Slot RV, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM
J Lipid Res. 2008
PubMed ID: 18660489
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Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kappaB and Brg-1.
Tai KY, Shieh YS, Lee CS, Shiah SG, Wu CW
Oncogene. 2008
PubMed ID: 18345028
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The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers.
Ni Z, Abou El Hassan M, Xu Z, Yu T, Bremner R
Nat Immunol. 2008
PubMed ID: 18500344
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Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z
Nat Cell Biol. 2008
PubMed ID: 18454139
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Switching of chromatin-remodelling complexes for oestrogen receptor-alpha.
Okada M, Takezawa S, Mezaki Y, Yamaoka I, Takada I, Kitagawa H, Kato S
EMBO Rep. 2008
PubMed ID: 18451880
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Targeted knockout of BRG1 potentiates lung cancer development.
Glaros S, Cirrincione GM, Palanca A, Metzger D, Reisman D
Cancer Res. 2008
PubMed ID: 18483251
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Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines.
Medina PP, Romero OA, Kohno T, Montuenga LM, Pio R, Yokota J, Sanchez-Cespedes M
Hum Mutat. 2008
PubMed ID: 18386774
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Determinants of a transcriptionally competent environment at the GM-CSF promoter.
Brettingham-Moore KH, Sprod OR, Chen X, Oakford P, Shannon MF, Holloway AF
Nucleic Acids Res. 2008
PubMed ID: 18344520
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Role of the mammalian SWI/SNF chromatin remodeling complex in the cellular response to UV damage.
Gong F, Fahy D, Liu H, Wang W, Smerdon MJ
Cell Cycle. 2008
PubMed ID: 18414052
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GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
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Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb).
Ito T, Watanabe H, Yamamichi N, Kondo S, Tando T, Haraguchi T, Mizutani T, Sakurai K, Fujita S, Izumi T, Isobe T, Iba H
Biochem J. 2008
PubMed ID: 18042045
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Interaction of the glucocorticoid receptor with the chromatin landscape.
John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, Voss TC, Davis SR, Meltzer PS, Stamatoyannopoulos JA, Hager GL
Mol Cell. 2008
PubMed ID: 18342607
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Inhibition of cyclin D1 gene transcription by Brg-1.
Rao M, Casimiro MC, Lisanti MP, D'Amico M, Wang C, Shirley LA, Leader JE, Liu M, Stallcup M, Engel DA, Murphy DJ, Pestell RG
Cell Cycle. 2008
PubMed ID: 18239461
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SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.
Han D, Jeon S, Sohn DH, Lee C, Ahn S, Kim WK, Chung H, Seong RH
Dev Biol. 2008
PubMed ID: 18206867
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Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.
Stankunas K, Hang CT, Tsun ZY, Chen H, Lee NV, Wu JI, Shang C, Bayle JH, Shou W, Iruela-Arispe ML, Chang CP
Dev Cell. 2008
PubMed ID: 18267097
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The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.
Griffin CT, Brennan J, Magnuson T
Development. 2008
PubMed ID: 18094026
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The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.
Trotter KW, Fan HY, Ivey ML, Kingston RE, Archer TK
Mol Cell Biol. 2008
PubMed ID: 18086889
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Characterization of mammary tumors from Brg1 heterozygous mice.
Bultman SJ, Herschkowitz JI, Godfrey V, Gebuhr TC, Yaniv M, Perou CM, Magnuson T
Oncogene. 2008
PubMed ID: 17637742
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Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.
Xi Q, He W, Zhang XH, Le HV, Massagué J
J Biol Chem. 2008
PubMed ID: 18003620
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Chromatin remodeling and SWI/SNF2 factors in human disease.
Kokavec J, Podskocova J, Zavadil J, Stopka T
Front Biosci. 2008
PubMed ID: 18508648
-
The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes.
Xu Y, Zhang J, Chen X
J Biol Chem. 2007
PubMed ID: 17938176
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Activity-dependent neuroprotective protein constitutes a novel element in the SWI/SNF chromatin remodeling complex.
Mandel S, Gozes I
J Biol Chem. 2007
PubMed ID: 17878164
-
HMGA1 mediates the activation of the CRYAB promoter by BRG1.
Duncan B, Zhao K
DNA Cell Biol. 2007
PubMed ID: 17723105
-
Nuclear actin is involved in the regulation of CSF1 gene transcription in a chromatin required, BRG1 independent manner.
Song Z, Wang M, Wang X, Pan X, Liu W, Hao S, Zeng X
J Cell Biochem. 2007
PubMed ID: 17393431
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P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNgamma.
Christova R, Jones T, Wu PJ, Bolzer A, Costa-Pereira AP, Watling D, Kerr IM, Sheer D
J Cell Sci. 2007
PubMed ID: 17726060
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EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W
Brief Funct Genomic Proteomic. 2007
PubMed ID: 17967808
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A novel role of Brg1 in the regulation of SRF/MRTFA-dependent smooth muscle-specific gene expression.
Zhang M, Fang H, Zhou J, Herring BP
J Biol Chem. 2007
PubMed ID: 17599918
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Brg1 chromatin remodeling factor is involved in cell growth arrest, apoptosis and senescence of rat mesenchymal stem cells.
Napolitano MA, Cipollaro M, Cascino A, Melone MA, Giordano A, Galderisi U
J Cell Sci. 2007
PubMed ID: 17666433
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Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.
Singh M, Popowicz GM, Krajewski M, Holak TA
Chembiochem. 2007
PubMed ID: 17582821
-
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B
Mol Cell. 2007
PubMed ID: 17643375
-
An essential switch in subunit composition of a chromatin remodeling complex during neural development.
Lessard J, Wu JI, Ranish JA, Wan M, Winslow MM, Staahl BT, Wu H, Aebersold R, Graef IA, Crabtree GR
Neuron. 2007
PubMed ID: 17640523
-
Sequential recruitment of PCAF and BRG1 contributes to myogenin activation in 12-O-tetradecanoylphorbol-13-acetate-induced early differentiation of rhabdomyosarcoma-derived cells.
Li ZY, Yang J, Gao X, Lu JY, Zhang Y, Wang K, Cheng MB, Wu NH, Zhang Y, Wu Z, Shen YF
J Biol Chem. 2007
PubMed ID: 17468105
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Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation.
Kim SI, Bultman SJ, Jing H, Blobel GA, Bresnick EH
Mol Cell Biol. 2007
PubMed ID: 17438135
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ
Science. 2007
PubMed ID: 17525332
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Extracellular matrix-regulated gene expression requires cooperation of SWI/SNF and transcription factors.
Xu R, Spencer VA, Bissell MJ
J Biol Chem. 2007
PubMed ID: 17387179
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Estrogen receptor alpha and the activating protein-1 complex cooperate during insulin-like growth factor-I-induced transcriptional activation of the pS2/TFF1 gene.
Baron S, Escande A, Albérola G, Bystricky K, Balaguer P, Richard-Foy H
J Biol Chem. 2007
PubMed ID: 17317669
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Myogenin and the SWI/SNF ATPase Brg1 maintain myogenic gene expression at different stages of skeletal myogenesis.
Ohkawa Y, Yoshimura S, Higashi C, Marfella CG, Dacwag CS, Tachibana T, Imbalzano AN
J Biol Chem. 2007
PubMed ID: 17194702
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Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails.
Shen W, Xu C, Huang W, Zhang J, Carlson JE, Tu X, Wu J, Shi Y
Biochemistry. 2007
PubMed ID: 17274598
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Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.
Nagl NG, Wang X, Patsialou A, Van Scoy M, Moran E
EMBO J. 2007
PubMed ID: 17255939
-
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.
Cannavo E, Gerrits B, Marra G, Schlapbach R, Jiricny J
J Biol Chem. 2007
PubMed ID: 17148452
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Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.
Sun A, Tawfik O, Gayed B, Thrasher JB, Hoestje S, Li C, Li B
Prostate. 2007
PubMed ID: 17075831
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Large-scale phosphorylation analysis of mouse liver.
Villén J, Beausoleil SA, Gerber SA, Gygi SP
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17242355
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LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes.
Chang DF, Belaguli NS, Chang J, Schwartz RJ
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17185421
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Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.
Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M
Genome Biol. 2007
PubMed ID: 17672918
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Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
-
Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry.
Dai J, Jin WH, Sheng QH, Shieh CH, Wu JR, Zeng R
J Proteome Res. 2007
PubMed ID: 17203969
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Brahma-related gene 1-dependent STAT3 recruitment at IL-6-inducible genes.
Ni Z, Bremner R
J Immunol. 2007
PubMed ID: 17182572
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Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression.
Lee YS, Sohn DH, Han D, Lee HW, Seong RH, Kim JB
Mol Cell Biol. 2007
PubMed ID: 17074803
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The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling.
Dacwag CS, Ohkawa Y, Pal S, Sif S, Imbalzano AN
Mol Cell Biol. 2007
PubMed ID: 17043109
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BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression.
Ooi L, Belyaev ND, Miyake K, Wood IC, Buckley NJ
J Biol Chem. 2006
PubMed ID: 17023429
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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
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BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress.
Zhang J, Ohta T, Maruyama A, Hosoya T, Nishikawa K, Maher JM, Shibahara S, Itoh K, Yamamoto M
Mol Cell Biol. 2006
PubMed ID: 16923960
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Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.
Bilodeau S, Vallette-Kasic S, Gauthier Y, Figarella-Branger D, Brue T, Berthelet F, Lacroix A, Batista D, Stratakis C, Hanson J, Meij B, Drouin J
Genes Dev. 2006
PubMed ID: 17043312
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Recruitment of the SWI/SNF protein Brg1 by a multiprotein complex effects transcriptional repression in murine erythroid progenitors.
Xu Z, Meng X, Cai Y, Koury MJ, Brandt SJ
Biochem J. 2006
PubMed ID: 16800816
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DNA-binding properties of the recombinant high-mobility-group-like AT-hook-containing region from human BRG1 protein.
Singh M, D'Silva L, Holak TA
Biol Chem. 2006
PubMed ID: 17081121
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The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.
Caretti G, Schiltz RL, Dilworth FJ, Di Padova M, Zhao P, Ogryzko V, Fuller-Pace FV, Hoffman EP, Tapscott SJ, Sartorelli V
Dev Cell. 2006
PubMed ID: 17011493
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Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.
Park JH, Park EJ, Lee HS, Kim SJ, Hur SK, Imbalzano AN, Kwon J
EMBO J. 2006
PubMed ID: 16932743
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Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.
Hu K, Nan X, Bird A, Wang W
Nat Genet. 2006
PubMed ID: 16940996
-
A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.
Tsang HT, Connell JW, Brown SE, Thompson A, Reid E, Sanderson CM
Genomics. 2006
PubMed ID: 16730941
-
Heat shock transcription factor (Hsf)-4b recruits Brg1 during the G1 phase of the cell cycle and regulates the expression of heat shock proteins.
Tu N, Hu Y, Mivechi NF
J Cell Biochem. 2006
PubMed ID: 16552721
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Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors.
Gordon MD, Nusse R
J Biol Chem. 2006
PubMed ID: 16793760
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Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ
Hum Mol Genet. 2006
PubMed ID: 16787967
-
Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote.
Torres-Padilla ME, Zernicka-Goetz M
J Cell Biol. 2006
PubMed ID: 16880268
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The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.
Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E
J Biol Chem. 2006
PubMed ID: 16687403
-
Maternal BRG1 regulates zygotic genome activation in the mouse.
Bultman SJ, Gebuhr TC, Pan H, Svoboda P, Schultz RM, Magnuson T
Genes Dev. 2006
PubMed ID: 16818606
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New insights into BS69 functions.
Velasco G, Grkovic S, Ansieau S
J Biol Chem. 2006
PubMed ID: 16565076
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T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent.
Zhang F, Boothby M
J Exp Med. 2006
PubMed ID: 16717115
-
Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.
He W, Dorn DC, Erdjument-Bromage H, Tempst P, Moore MA, Massagué J
Cell. 2006
PubMed ID: 16751102
-
Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.
Yang Y, Stopka T, Golestaneh N, Wang Y, Wu K, Li A, Chauhan BK, Gao CY, Cveklová K, Duncan MK, Pestell RG, Chepelinsky AB, Skoultchi AI, Cvekl A
EMBO J. 2006
PubMed ID: 16675956
-
Isolation of an scFv targeting BRG1 using phage display with characterization by AFM.
Marcus WD, Wang H, Lohr D, Sierks MR, Lindsay SM
Biochem Biophys Res Commun. 2006
PubMed ID: 16513088
-
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
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Cooperative activity of BRG1 and Z-DNA formation in chromatin remodeling.
Liu H, Mulholland N, Fu H, Zhao K
Mol Cell Biol. 2006
PubMed ID: 16537901
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Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.
Ohkawa Y, Marfella CG, Imbalzano AN
EMBO J. 2006
PubMed ID: 16424906
-
Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.
Inayoshi Y, Miyake K, Machida Y, Kaneoka H, Terajima M, Dohda T, Takahashi M, Iijima S
J Biochem. 2006
PubMed ID: 16452305
-
Brg1 is required for murine neural stem cell maintenance and gliogenesis.
Matsumoto S, Banine F, Struve J, Xing R, Adams C, Liu Y, Metzger D, Chambon P, Rao MS, Sherman LS
Dev Biol. 2006
PubMed ID: 16330018
-
Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription.
Agbottah E, Deng L, Dannenberg LO, Pumfery A, Kashanchi F
Retrovirology. 2006
PubMed ID: 16893449
-
Epigenetic alterations of BRG1 leads to cancer development through its nuclear-cytoplasmic shuttling abnormalities.
Gunduz E, Gunduz M, Nagatsuka H, Beder L, Demircan K, Tamamura R, Hatipoglu OF, Mahmut N, Katase N, Naomoto Y, Nagai N
Med Hypotheses. 2006
PubMed ID: 16824695
-
High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.
Yoshikawa T, Piao Y, Zhong J, Matoba R, Carter MG, Wang Y, Goldberg I, Ko MS
Gene Expr Patterns. 2006
PubMed ID: 16325481
-
Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes.
Vradii D, Wagner S, Doan DN, Nickerson JA, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Imbalzano AN, Stein GS
J Cell Physiol. 2006
PubMed ID: 15965950
-
Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells.
Datta J, Majumder S, Bai S, Ghoshal K, Kutay H, Smith DS, Crabb JW, Jacob ST
Cancer Res. 2005
PubMed ID: 16322236
-
A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development.
Bultman SJ, Gebuhr TC, Magnuson T
Genes Dev. 2005
PubMed ID: 16287714
-
Analysis of BCL6-interacting proteins by tandem mass spectrometry.
Miles RR, Crockett DK, Lim MS, Elenitoba-Johnson KS
Mol Cell Proteomics. 2005
PubMed ID: 16147992
-
hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes.
Huang CY, Beliakoff J, Li X, Lee J, Li X, Sharma M, Lim B, Sun Z
Mol Endocrinol. 2005
PubMed ID: 16051670
-
Ligand-induced transrepression by VDR through association of WSTF with acetylated histones.
Fujiki R, Kim MS, Sasaki Y, Yoshimura K, Kitagawa H, Kato S
EMBO J. 2005
PubMed ID: 16252006
-
BRG1 loss in MiaPaCa2 cells induces an altered cellular morphology and disruption in the organization of the actin cytoskeleton.
Rosson GB, Bartlett C, Reed W, Weissman BE
J Cell Physiol. 2005
PubMed ID: 15887247
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Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region.
Mahajan MC, Narlikar GJ, Boyapaty G, Kingston RE, Weissman SM
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16217013
-
The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.
Nagl NG, Patsialou A, Haines DS, Dallas PB, Beck GR, Moran E
Cancer Res. 2005
PubMed ID: 16230384
-
Apical role for BRG1 in cytokine-induced promoter assembly.
Ni Z, Karaskov E, Yu T, Callaghan SM, Der S, Park DS, Xu Z, Pattenden SG, Bremner R
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16195385
-
Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation.
Indra AK, Dupé V, Bornert JM, Messaddeq N, Yaniv M, Mark M, Chambon P, Metzger D
Development. 2005
PubMed ID: 16192310
-
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
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Science. 2005
PubMed ID: 16141072
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Geminin regulates neuronal differentiation by antagonizing Brg1 activity.
Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL
Genes Dev. 2005
PubMed ID: 16024661
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PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.
Yan Z, Cui K, Murray DM, Ling C, Xue Y, Gerstein A, Parsons R, Zhao K, Wang W
Genes Dev. 2005
PubMed ID: 15985610
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BAF complex is closely related to and interacts with NF1/CTF and RNA polymerase II in gene transcriptional activation.
Zhao LH, Ba XQ, Wang XG, Zhu XJ, Wang L, Zeng XL
Acta Biochim Biophys Sin (Shanghai). 2005
PubMed ID: 15999204
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The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.
Lechner MS, Schultz DC, Negorev D, Maul GG, Rauscher FJ
Biochem Biophys Res Commun. 2005
PubMed ID: 15882967
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Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.
Huuskonen J, Vishnu M, Fielding PE, Fielding CJ
Arterioscler Thromb Vasc Biol. 2005
PubMed ID: 15774904
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MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex.
de la Serna IL, Ohkawa Y, Berkes CA, Bergstrom DA, Dacwag CS, Tapscott SJ, Imbalzano AN
Mol Cell Biol. 2005
PubMed ID: 15870273
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Multiple interactions between BRG1 and MHC class II promoter binding proteins.
Mudhasani R, Fontes JD
Mol Immunol. 2005
PubMed ID: 15781111
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Ikaros SUMOylation: switching out of repression.
Gómez-del Arco P, Koipally J, Georgopoulos K
Mol Cell Biol. 2005
PubMed ID: 15767674
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Transcriptional targets of the chromatin-remodelling factor SMARCA4/BRG1 in lung cancer cells.
Medina PP, Carretero J, Ballestar E, Angulo B, Lopez-Rios F, Esteller M, Sanchez-Cespedes M
Hum Mol Genet. 2005
PubMed ID: 15731117
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Swapping function of two chromatin remodeling complexes.
Fan HY, Trotter KW, Archer TK, Kingston RE
Mol Cell. 2005
PubMed ID: 15780937
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Mediator requirement for both recruitment and postrecruitment steps in transcription initiation.
Wang G, Balamotis MA, Stevens JL, Yamaguchi Y, Handa H, Berk AJ
Mol Cell. 2005
PubMed ID: 15749018
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SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.
Young DW, Pratap J, Javed A, Weiner B, Ohkawa Y, van Wijnen A, Montecino M, Stein GS, Stein JL, Imbalzano AN, Lian JB
J Cell Biochem. 2005
PubMed ID: 15565649
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Histone modifications defining active genes persist after transcriptional and mitotic inactivation.
Kouskouti A, Talianidis I
EMBO J. 2005
PubMed ID: 15616580
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Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
Nature. 2005
PubMed ID: 15635413
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Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
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The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.
Seo S, Richardson GA, Kroll KL
Development. 2005
PubMed ID: 15576411
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Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
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Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
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Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene.
Wang F, Zhang R, Beischlag TV, Muchardt C, Yaniv M, Hankinson O
J Biol Chem. 2004
PubMed ID: 15347669
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Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.
Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG
Nature. 2004
PubMed ID: 15525990
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Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis.
Dasgupta P, Sun J, Wang S, Fusaro G, Betts V, Padmanabhan J, Sebti SM, Chellappan SP
Mol Cell Biol. 2004
PubMed ID: 15485920
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Brg-1 is required for maximal transcription of the human matrix metalloproteinase-2 gene.
Ma Z, Chang MJ, Shah R, Adamski J, Zhao X, Benveniste EN
J Biol Chem. 2004
PubMed ID: 15317818
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Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.
Wang X, Nagl NG, Wilsker D, Van Scoy M, Pacchione S, Yaciuk P, Dallas PB, Moran E
Biochem J. 2004
PubMed ID: 15170388
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
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Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.
Medina PP, Carretero J, Fraga MF, Esteller M, Sidransky D, Sanchez-Cespedes M
Genes Chromosomes Cancer. 2004
PubMed ID: 15287030
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Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene.
Giraud S, Hurlstone A, Avril S, Coqueret O
Oncogene. 2004
PubMed ID: 15286705
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Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15302935
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Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.
Stoletov KV, Terman BI
Biochem Biophys Res Commun. 2004
PubMed ID: 15207703
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Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.
Fukuoka J, Fujii T, Shih JH, Dracheva T, Meerzaman D, Player A, Hong K, Settnek S, Gupta A, Buetow K, Hewitt S, Travis WD, Jen J
Clin Cancer Res. 2004
PubMed ID: 15240517
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A protein interaction framework for human mRNA degradation.
Lehner B, Sanderson CM
Genome Res. 2004
PubMed ID: 15231747
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BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.
Wang S, Zhang B, Faller DV
EMBO J. 2004
PubMed ID: 15141164
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Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor gamma nuclear hormone receptor.
Salma N, Xiao H, Mueller E, Imbalzano AN
Mol Cell Biol. 2004
PubMed ID: 15143161
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The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.
Medjkane S, Novikov E, Versteege I, Delattre O
Cancer Res. 2004
PubMed ID: 15150092
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Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells.
Wang Q, Udayakumar TS, Vasaitis TS, Brodie AM, Fondell JD
J Biol Chem. 2004
PubMed ID: 14966121
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Loss of the INI1 tumor suppressor does not impair the expression of multiple BRG1-dependent genes or the assembly of SWI/SNF enzymes.
Doan DN, Veal TM, Yan Z, Wang W, Jones SN, Imbalzano AN
Oncogene. 2004
PubMed ID: 14990991
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Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.
Debril MB, Gelman L, Fayard E, Annicotte JS, Rocchi S, Auwerx J
J Biol Chem. 2004
PubMed ID: 14701856
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The DNA sequence and biology of human chromosome 19.
Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM
Nature. 2004
PubMed ID: 15057824
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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
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BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2.
Hill DA, de la Serna IL, Veal TM, Imbalzano AN
J Cell Biochem. 2004
PubMed ID: 15034933
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Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization.
Powles N, Babbs C, Ficker M, Schimmang T, Maconochie M
Dev Biol. 2004
PubMed ID: 15031102
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Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.
Brajenovic M, Joberty G, Küster B, Bouwmeester T, Drewes G
J Biol Chem. 2004
PubMed ID: 14676191
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A small modulatory dsRNA specifies the fate of adult neural stem cells.
Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH
Cell. 2004
PubMed ID: 15035981
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TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival.
Liu K, Luo Y, Lin FT, Lin WC
Genes Dev. 2004
PubMed ID: 15075294
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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G
Nat Cell Biol. 2004
PubMed ID: 14743216
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A methylation-mediator complex in hormone signaling.
Xu W, Cho H, Kadam S, Banayo EM, Anderson S, Yates JR, Emerson BM, Evans RM
Genes Dev. 2004
PubMed ID: 14729568
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Protein profile of tax-associated complexes.
Wu K, Bottazzi ME, de la Fuente C, Deng L, Gitlin SD, Maddukuri A, Dadgar S, Li H, Vertes A, Pumfery A, Kashanchi F
J Biol Chem. 2004
PubMed ID: 14530271
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
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The early embryonic expression of TFII-I during mouse preimplantation development.
Enkhmandakh B, Bitchevaia N, Ruddle F, Bayarsaihan D
Gene Expr Patterns. 2004
PubMed ID: 14678824
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Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter.
Henderson A, Holloway A, Reeves R, Tremethick DJ
Mol Cell Biol. 2004
PubMed ID: 14673171
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Mi-2 beta associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities.
Shimono Y, Murakami H, Kawai K, Wade PA, Shimokata K, Takahashi M
J Biol Chem. 2003
PubMed ID: 14530259
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The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development.
Gebuhr TC, Kovalev GI, Bultman S, Godfrey V, Su L, Magnuson T
J Exp Med. 2003
PubMed ID: 14676303
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EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
Chi Y, Senyuk V, Chakraborty S, Nucifora G
J Biol Chem. 2003
PubMed ID: 14555651
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
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Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers.
Perani M, Ingram CJ, Cooper CS, Garrett MD, Goodwin GH
Oncogene. 2003
PubMed ID: 14603256
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mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.
Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, Kumar J, Tempst P, Sif S
Mol Cell Biol. 2003
PubMed ID: 14559996
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Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.
Reuter TY, Medhurst AL, Waisfisz Q, Zhi Y, Herterich S, Hoehn H, Gross HJ, Joenje H, Hoatlin ME, Mathew CG, Huber PA
Exp Cell Res. 2003
PubMed ID: 14499622
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Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4.
Morshead KB, Ciccone DN, Taverna SD, Allis CD, Oettinger MA
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14500909
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BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.
Hsiao PW, Fryer CJ, Trotter KW, Wang W, Archer TK
Mol Cell Biol. 2003
PubMed ID: 12917342
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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
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Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development.
Chi TH, Wan M, Lee PP, Akashi K, Metzger D, Chambon P, Wilson CB, Crabtree GR
Immunity. 2003
PubMed ID: 12932351
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Expression of the Wdr9 gene and protein products during mouse development.
Huang H, Rambaldi I, Daniels E, Featherstone M
Dev Dyn. 2003
PubMed ID: 12889071
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The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.
Kitagawa H, Fujiki R, Yoshimura K, Mezaki Y, Uematsu Y, Matsui D, Ogawa S, Unno K, Okubo M, Tokita A, Nakagawa T, Ito T, Ishimi Y, Nagasawa H, Matsumoto T, Yanagisawa J, Kato S
Cell. 2003
PubMed ID: 12837248
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Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
Baker KM, Wei G, Schaffner AE, Ostrowski MC
J Biol Chem. 2003
PubMed ID: 12637547
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Mutation analysis of the BRG1 gene in prostate cancer clinical samples.
Valdman A, Nordenskjöld A, Fang X, Naito A, Al-Shukri S, Larsson C, Ekman P, Li C
Int J Oncol. 2003
PubMed ID: 12684665
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Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation.
Gwack Y, Baek HJ, Nakamura H, Lee SH, Meisterernst M, Roeder RG, Jung JU
Mol Cell Biol. 2003
PubMed ID: 12612078
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SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.
Yamamichi-Nishina M, Ito T, Mizutani T, Yamamichi N, Watanabe H, Iba H
J Biol Chem. 2003
PubMed ID: 12493776
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Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.
Kadam S, Emerson BM
Mol Cell. 2003
PubMed ID: 12620226
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Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.
Reisman DN, Sciarrotta J, Wang W, Funkhouser WK, Weissman BE
Cancer Res. 2003
PubMed ID: 12566296
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BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
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Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha.
Nielsen AL, Sanchez C, Ichinose H, Cerviño M, Lerouge T, Chambon P, Losson R
EMBO J. 2002
PubMed ID: 12411497
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Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.
Inoue H, Furukawa T, Giannakopoulos S, Zhou S, King DS, Tanese N
J Biol Chem. 2002
PubMed ID: 12200431
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REST repression of neuronal genes requires components of the hSWI.SNF complex.
Battaglioli E, Andrés ME, Rose DW, Chenoweth JG, Rosenfeld MG, Anderson ME, Mandel G
J Biol Chem. 2002
PubMed ID: 12192000
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Identification of a polymorphic, neuron-specific chromatin remodeling complex.
Olave I, Wang W, Xue Y, Kuo A, Crabtree GR
Genes Dev. 2002
PubMed ID: 12368262
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Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.
Huang M, Qian F, Hu Y, Ang C, Li Z, Wen Z
Nat Cell Biol. 2002
PubMed ID: 12244326
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Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex.
Liu H, Kang H, Liu R, Chen X, Zhao K
Mol Cell Biol. 2002
PubMed ID: 12192045
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The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme.
Chiba N, Parvin JD
Cancer Res. 2002
PubMed ID: 12154023
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Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.
Chi TH, Wan M, Zhao K, Taniuchi I, Chen L, Littman DR, Crabtree GR
Nature. 2002
PubMed ID: 12110891
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The class II transactivator requires brahma-related gene 1 to activate transcription of major histocompatibility complex class II genes.
Mudhasani R, Fontes JD
Mol Cell Biol. 2002
PubMed ID: 12077331
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SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription.
Lee D, Kim JW, Seo T, Hwang SG, Choi EJ, Choe J
J Biol Chem. 2002
PubMed ID: 11950834
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Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth.
Wang S, Zhang B, Faller DV
EMBO J. 2002
PubMed ID: 12065415
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A putative nuclear receptor coactivator (TMF/ARA160) associates with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the Golgi apparatus.
Mori K, Kato H
FEBS Lett. 2002
PubMed ID: 12044884
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Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.
Hurlstone AF, Olave IA, Barker N, van Noort M, Clevers H
Biochem J. 2002
PubMed ID: 11988099
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Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent.
Pattenden SG, Klose R, Karaskov E, Bremner R
EMBO J. 2002
PubMed ID: 11953317
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Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex.
Wang S, Hankinson O
J Biol Chem. 2002
PubMed ID: 11805098
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Chromatin remodeling: nucleosomes bulging at the seams.
Peterson CL
Curr Biol. 2002
PubMed ID: 11937040
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BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation.
Park J, Wood MA, Cole MD
Mol Cell Biol. 2002
PubMed ID: 11839798
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SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.
Kato H, Tjernberg A, Zhang W, Krutchinsky AN, An W, Takeuchi T, Ohtsuki Y, Sugano S, de Bruijn DR, Chait BT, Roeder RG
J Biol Chem. 2002
PubMed ID: 11734557
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Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.
Strobeck MW, Reisman DN, Gunawardena RW, Betz BL, Angus SP, Knudsen KE, Kowalik TF, Weissman BE, Knudsen ES
J Biol Chem. 2002
PubMed ID: 11719516
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Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).
Kuzmichev A, Zhang Y, Erdjument-Bromage H, Tempst P, Reinberg D
Mol Cell Biol. 2002
PubMed ID: 11784859
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Generation and interconversion of multiple distinct nucleosomal states as a mechanism for catalyzing chromatin fluidity.
Narlikar GJ, Phelan ML, Kingston RE
Mol Cell. 2001
PubMed ID: 11779498
-
Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.
Otsuki T, Furukawa Y, Ikeda K, Endo H, Yamashita T, Shinohara A, Iwamatsu A, Ozawa K, Liu JM
Hum Mol Genet. 2001
PubMed ID: 11726552
-
Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development.
Kim JK, Huh SO, Choi H, Lee KS, Shin D, Lee C, Nam JS, Kim H, Chung H, Lee HW, Park SD, Seong RH
Mol Cell Biol. 2001
PubMed ID: 11604513
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The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation.
Barker N, Hurlstone A, Musisi H, Miles A, Bienz M, Clevers H
EMBO J. 2001
PubMed ID: 11532957
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Transcriptional activation domains of human heat shock factor 1 recruit human SWI/SNF.
Sullivan EK, Weirich CS, Guyon JR, Sif S, Kingston RE
Mol Cell Biol. 2001
PubMed ID: 11486022
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LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest.
Marignani PA, Kanai F, Carpenter CL
J Biol Chem. 2001
PubMed ID: 11445556
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Mutation analyses of 268 candidate genes in human tumor cell lines.
Teng DH, Chen Y, Lian L, Ha PC, Tavtigian SV, Wong AK
Genomics. 2001
PubMed ID: 11414763
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The product of an oculopharyngeal muscular dystrophy gene, poly(A)-binding protein 2, interacts with SKIP and stimulates muscle-specific gene expression.
Kim YJ, Noguchi S, Hayashi YK, Tsukahara T, Shimizu T, Arahata K
Hum Mol Genet. 2001
PubMed ID: 11371506
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Novel glucocorticoid receptor coactivator effector mechanisms.
Jenkins BD, Pullen CB, Darimont BD
Trends Endocrinol Metab. 2001
PubMed ID: 11306337
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The BRG-1 subunit of the SWI/SNF complex regulates CD44 expression.
Strobeck MW, DeCristofaro MF, Banine F, Weissman BE, Sherman LS, Knudsen ES
J Biol Chem. 2001
PubMed ID: 11108719
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Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.
Sif S, Saurin AJ, Imbalzano AN, Kingston RE
Genes Dev. 2001
PubMed ID: 11238380
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BRM (SNF2alpha) expression is concomitant to the onset of vasculogenesis in early mouse postimplantation development.
Dauvillier S, Ott MO, Renard JP, Legouy E
Mech Dev. 2001
PubMed ID: 11231080
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Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
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A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.
Underhill C, Qutob MS, Yee SP, Torchia J
J Biol Chem. 2000
PubMed ID: 11013263
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A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.
Bultman S, Gebuhr T, Yee D, La Mantia C, Nicholson J, Gilliam A, Randazzo F, Metzger D, Chambon P, Crabtree G, Magnuson T
Mol Cell. 2000
PubMed ID: 11163203
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The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.
Xue Y, Canman JC, Lee CS, Nie Z, Yang D, Moreno GT, Young MK, Salmon ED, Wang W
Proc Natl Acad Sci U S A. 2000
PubMed ID: 11078522
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BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines.
Wong AK, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K, Ghaffari S, Iliev D, Penn B, Woodland AM, Smith R, Salada G, Carillo A, Laity K, Gupte J, Swedlund B, Tavtigian SV, Teng DH, Lees E
Cancer Res. 2000
PubMed ID: 11085541
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RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
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Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
-
Functional selectivity of recombinant mammalian SWI/SNF subunits.
Kadam S, McAlpine GS, Phelan ML, Kingston RE, Jones KA, Emerson BM
Genes Dev. 2000
PubMed ID: 11018012
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An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.
O'Neill DW, Schoetz SS, Lopez RA, Castle M, Rabinowitz L, Shor E, Krawchuk D, Goll MG, Renz M, Seelig HP, Han S, Seong RH, Park SD, Agalioti T, Munshi N, Thanos D, Erdjument-Bromage H, Tempst P, Bank A
Mol Cell Biol. 2000
PubMed ID: 11003653
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BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation.
DiRenzo J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M
Mol Cell Biol. 2000
PubMed ID: 11003650
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Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3.
Li J, Wang J, Wang J, Nawaz Z, Liu JM, Qin J, Wong J
EMBO J. 2000
PubMed ID: 10944117
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Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.
Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R
Cell. 2000
PubMed ID: 10943845
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Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
Zhang HS, Gavin M, Dahiya A, Postigo AA, Ma D, Luo RX, Harbour JW, Dean DC
Cell. 2000
PubMed ID: 10778858
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Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau1 activation domain.
Wallberg AE, Neely KE, Hassan AH, Gustafsson JA, Workman JL, Wright AP
Mol Cell Biol. 2000
PubMed ID: 10688647
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A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.
Kowenz-Leutz E, Leutz A
Mol Cell. 1999
PubMed ID: 10619021
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The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin.
Remboutsika E, Lutz Y, Gansmuller A, Vonesch JL, Losson R, Chambon P
J Cell Sci. 1999
PubMed ID: 10318760
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Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.
Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K
Immunity. 1999
PubMed ID: 10204490
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Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest.
Shanahan F, Seghezzi W, Parry D, Mahony D, Lees E
Mol Cell Biol. 1999
PubMed ID: 9891079
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Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.
Phelan ML, Sif S, Narlikar GJ, Kingston RE
Mol Cell. 1999
PubMed ID: 10078207
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High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
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Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).
Reyes JC, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M
EMBO J. 1998
PubMed ID: 9843504
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Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling.
Zhao K, Wang W, Rando OJ, Xue Y, Swiderek K, Kuo A, Crabtree GR
Cell. 1998
PubMed ID: 9845365
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Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.
Sif S, Stukenberg PT, Kirschner MW, Kingston RE
Genes Dev. 1998
PubMed ID: 9744861
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p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.
Dallas PB, Cheney IW, Liao DW, Bowrin V, Byam W, Pacchione S, Kobayashi R, Yaciuk P, Moran E
Mol Cell Biol. 1998
PubMed ID: 9584200
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Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.
Fryer CJ, Archer TK
Nature. 1998
PubMed ID: 9590696
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Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.
LeGouy E, Thompson EM, Muchardt C, Renard JP
Dev Dyn. 1998
PubMed ID: 9603422
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Factors associated with the mammalian RNA polymerase II holoenzyme.
Neish AS, Anderson SF, Schlegel BP, Wei W, Parvin JD
Nucleic Acids Res. 1998
PubMed ID: 9443979
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SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.
Sumi-Ichinose C, Ichinose H, Metzger D, Chambon P
Mol Cell Biol. 1997
PubMed ID: 9315656
-
Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.
Reyes JC, Muchardt C, Yaniv M
J Cell Biol. 1997
PubMed ID: 9128241
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Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.
Ichinose H, Garnier JM, Chambon P, Losson R
Gene. 1997
PubMed ID: 9099865
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Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex.
Ostlund Farrants AK, Blomquist P, Kwon H, Wrange O
Mol Cell Biol. 1997
PubMed ID: 9001244
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A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
Le Douarin B, Nielsen AL, Garnier JM, Ichinose H, Jeanmougin F, Losson R, Chambon P
EMBO J. 1996
PubMed ID: 8978696
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A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor.
Nair SC, Toran EJ, Rimerman RA, Hjermstad S, Smithgall TE, Smith DF
Cell Stress Chaperones. 1996
PubMed ID: 9222609
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Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
Wang W, Côté J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL, Crabtree GR
EMBO J. 1996
PubMed ID: 8895581
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Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
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Diversity and specialization of mammalian SWI/SNF complexes.
Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR
Genes Dev. 1996
PubMed ID: 8804307
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The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.
Muchardt C, Reyes JC, Bourachot B, Leguoy E, Yaniv M
EMBO J. 1996
PubMed ID: 8670841
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A novel putative helicase produced in early murine lymphocytes.
Jarvis CD, Geiman T, Vila-Storm MP, Osipovich O, Akella U, Candeias S, Nathan I, Durum SK, Muegge K
Gene. 1996
PubMed ID: 8647447
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Sensing stress and responding to stress.
Voellmy R
EXS. 1996
PubMed ID: 8856972
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A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm.
Muchardt C, Sardet C, Bourachot B, Onufryk C, Yaniv M
Nucleic Acids Res. 1995
PubMed ID: 7739891
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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP
Cell. 1994
PubMed ID: 7923370
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Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.
Chiba H, Muramatsu M, Nomoto A, Kato H
Nucleic Acids Res. 1994
PubMed ID: 8208605
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brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator.
Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J
Dev Biol. 1994
PubMed ID: 7904967
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BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription.
Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR
Nature. 1993
PubMed ID: 8232556
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brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2.
Tamkun JW, Deuring R, Scott MP, Kissinger M, Pattatucci AM, Kaufman TC, Kennison JA
Cell. 1992
PubMed ID: 1346755
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RNA splicing. Alive with DEAD proteins.
Wassarman DA, Steitz JA
Nature. 1991
PubMed ID: 1825133
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