• About T1DBase
• Regions
  • Human T1D Regions
  • Mouse T1D Regions
    • Linkage Regions
    • Orthologous Regions
  • Rat T1D Regions
    • Linkage Regions
    • Orthologous Regions
    • QTL Regions
• Genome Browser
  • Human GBrowse
  • Mouse GBrowse
  • Rat GBrowse
• Tools
  • Gene Dossier
  • Beta Cell Gene Atlas
  • Batch Query
  • Sequence Search
  • HaemAtlas Search
  • Mouse Strain Search
• Data
  • Poster Pages
  • Downloads
  • Data Submission
• Help
  • FAQ
  • T1DBase Tutorial
• Contact Us

• Page Sections
  • Summary
  • Regions of Interest Overlapping this feature
  • Gene Overview
  • Beta Cell Gene Atlas
  • Tissue Expression
  • HaemAtlas Expression
  • Interactions
  • Cross-Reference to Pathways and GO Terms
  • Publications
  • Model Organism Phenotype Links
  • External Links
  • External resources (dkCOIN)

RXRB

Gene Description:   retinoid X receptor, beta; retinoid X receptor beta Synonyms:   Nr2b2, NR2B2, AL023085, MGC1831, RXR-beta, H-2RIIBP, RCoR-1, Rub, DAUDI6, Rxrb, RXRB Orthologs:   Human RXRB (protein-coding), Mouse Rxrb (protein-coding), Rat Rxrb (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid, KEGG Human-Rat: HomoloGene, MGD, RGD, Inparanoid, KEGG Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
MHC	Human	chr6:29910021..33498585	3.59	688

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd1	Mouse	chr17:34132973..35404440	1.27	98	6 no lod score

(Human) GRCh37 - chr6:33161365..33168630 (7.26 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr17:34168757..34175344 (6.59 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr20:4954336..4960880 (6.54 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for RXRB: The RXRB interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs RXRB   NR2E3   HPRD  empirical  10611353  RXRB   NR1H3   HPRD  empirical  15604093  RXRB   TACC2   HPRD  empirical  15207008  RXRB   CPLX1   IntAct  empirical  20195357  RXRB   NUDT21   IntAct  empirical  20195357  RXRB   AKAP13   HPRD, BioGRID  empirical  9627117  RXRB   CLTA   IntAct  empirical  20195357  RXRB   APCDD1   IntAct  empirical  20195357  RXRB   RAB3GAP1   IntAct  empirical  20195357  RXRB   APPL1   IntAct  empirical  20195357  RXRB   NR3C1   BioGRID  empirical  20211142  RXRB   GTF2B   MIPS  empirical  9442074  RXRB   GTF2H1   BioGRID  empirical  15625236  RXRB   KIF5A   IntAct  empirical  20195357  RXRB   MAP4   HPRD  empirical  15604093  RXRB   MBP   IntAct  empirical  20195357  RXRB   NR4A2   HPRD  empirical  7758108  7705655  15604093  RXRB   PCSK6   IntAct  empirical  20195357  RXRB   ATP5I   IntAct  empirical  20195357  RXRB   STX18   IntAct  empirical  20195357  RXRB   PPARD   HPRD  empirical  15604093  RXRB   PPARG   HPRD  empirical  15604093  RXRB   MED1   Reactome  predicted  10542397  10235266  16751179  15896744  15175151  11865025  9653119  RXRB   KLHL11   IntAct  empirical  20195357  RXRB   TMEM57   IntAct  empirical  20195357  RXRB   PPP3CA   IntAct  empirical  20195357  RXRB   PTMS   IntAct  empirical  20195357  RXRB   RARA   HPRD, MINT, IntAct, BioGRID  empirical  16189514  15604093  RXRB   RARB   HPRD  empirical  1331778  15604093  RXRB   RARG   HPRD  empirical  15604093  RXRB   RXRB   HPRD  empirical  11782480  RXRB   SOS2   IntAct  empirical  20195357  RXRB   SSB   IntAct  empirical  20195357  RXRB   TAF11   HPRD  empirical  8670810  RXRB   TBCA   IntAct  empirical  20195357  RXRB   THRA   HPRD  empirical  1331778  RXRB   THRB   HPRD  empirical  15604093  RXRB   NR2C2   HPRD  empirical  15604093  RXRB   HSP90B1   IntAct  empirical  20195357  RXRB   NR1H2   HPRD, BioGRID  empirical  10187832  15604093  RXRB   VCP   IntAct  empirical  20195357  RXRB   VDR   HPRD  empirical  15604093  RXRB   CACNA1B   IntAct  empirical  20195357  RXRB   DNAJB14   IntAct  empirical  20195357  RXRB   NCOA3   HPRD  empirical  9267036  RXRB   NRIP1   HPRD, BioGRID  empirical  12549917  12403842  9013766  11278635  9626662  RXRB   SPOP   HPRD, MINT, IntAct, BioGRID  empirical  16189514  RXRB   NR0B2   HPRD  empirical  10594021  RXRB   NCOA1   HPRD  empirical  7481822  RXRB   EIF3A   IntAct  empirical  20195357  RXRB   NR1I2   HPRD  empirical  9727070  15604093  RXRB   MCFD2   IntAct  empirical  20195357  RXRB   SGSM2   IntAct  empirical  20195357

View all

KEGG Network: 6   Adipocytokine signaling pathway Human - 4920 Mouse - 4920 Rat - 4920 Non-small cell lung cancer Human - 5223 Mouse - 5223 Rat - 5223 Pathways in cancer Human - 5200 Mouse - 5200 Rat - 5200 PPAR signaling pathway Human - 3320 Mouse - 3320 Rat - 3320 Small cell lung cancer Human - 5222 Mouse - 5222 Rat - 5222 Thyroid cancer Human - 5216 Mouse - 5216 Rat - 5216

Biocarta: None available   None available.

Reactome: 3   Gene Expression REACT_71 Generic Transcription Pathway REACT_12627 Nuclear Receptor transcription pathway REACT_15525

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 27   Sequence-specific DNA binding transcription factor activity GO:0003700 Ligand-regulated transcription factor activity GO:0003706 Steroid hormone receptor activity GO:0003707 Transcription coactivator activity GO:0003713 Receptor activity GO:0004872 Retinoid-X receptor activity GO:0004886 Steroid binding GO:0005496 Protein binding GO:0005515 Nucleus GO:0005634 Nucleoplasm GO:0005654 Transcription, DNA-dependent GO:0006351 Regulation of transcription, DNA-dependent GO:0006355 Zinc ion binding GO:0008270 Gene expression GO:0010467 Thyroid hormone receptor coactivator activity GO:0030375 Regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor GO:0034339 Vitamin D receptor binding GO:0042809 Retinoic acid receptor binding GO:0042974 Sequence-specific DNA binding GO:0043565 Transcription regulatory region DNA binding GO:0044212 Metal ion binding GO:0046872 Thyroid hormone receptor binding GO:0046966 Protein heterodimerization activity GO:0046982 Retinoic acid receptor signaling pathway GO:0048384 Ventricular cardiac muscle cell differentiation GO:0055012 Cardiac muscle cell proliferation GO:0060038 Cellular response to retinoic acid GO:0071300

	KEGG Network: 6 Adipocytokine signaling pathway Human - 4920 Mouse - 4920 Rat - 4920 Non-small cell lung cancer Human - 5223 Mouse - 5223 Rat - 5223 Pathways in cancer Human - 5200 Mouse - 5200 Rat - 5200 PPAR signaling pathway Human - 3320 Mouse - 3320 Rat - 3320 Small cell lung cancer Human - 5222 Mouse - 5222 Rat - 5222 Thyroid cancer Human - 5216 Mouse - 5216 Rat - 5216
	Biocarta: None available
	Reactome: 3 Gene Expression REACT_71 Generic Transcription Pathway REACT_12627 Nuclear Receptor transcription pathway REACT_15525
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 27 Sequence-specific DNA binding transcription factor activity GO:0003700 Ligand-regulated transcription factor activity GO:0003706 Steroid hormone receptor activity GO:0003707 Transcription coactivator activity GO:0003713 Receptor activity GO:0004872 Retinoid-X receptor activity GO:0004886 Steroid binding GO:0005496 Protein binding GO:0005515 Nucleus GO:0005634 Nucleoplasm GO:0005654 Transcription, DNA-dependent GO:0006351 Regulation of transcription, DNA-dependent GO:0006355 Zinc ion binding GO:0008270 Gene expression GO:0010467 Thyroid hormone receptor coactivator activity GO:0030375 Regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor GO:0034339 Vitamin D receptor binding GO:0042809 Retinoic acid receptor binding GO:0042974 Sequence-specific DNA binding GO:0043565 Transcription regulatory region DNA binding GO:0044212 Metal ion binding GO:0046872 Thyroid hormone receptor binding GO:0046966 Protein heterodimerization activity GO:0046982 Retinoic acid receptor signaling pathway GO:0048384 Ventricular cardiac muscle cell differentiation GO:0055012 Cardiac muscle cell proliferation GO:0060038 Cellular response to retinoic acid GO:0071300

Type 1 Diabetes Publications: 3

• Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.
  Miyazaki S, Taniguchi H, Moritoh Y, Tashiro F, Yamamoto T, Yamato E, Ikegami H, Ozato K, Miyazaki J
  Diabetes. 2010
  PubMed ID: 20798333
   
  
• Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes.
  van der Slik AR, van den Eng I, Eerligh P, Doxiadis II, Koeleman BP, Roep BO, Giphart MJ
  Tissue Antigens. 2007
  PubMed ID: 17389020
   
  
• Linkage disequilibrium between HLA-DPB1 alleles and retinoid X receptor beta haplotypes.
  Rajsbaum R, Fici D, Boggs DA, Fraser PA, Flores-Villanueva PO, Awdeh ZL
  Hum Immunol. 2002
  PubMed ID: 12175732
   
  

Publications: 180

• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
  Diabetes Care. 2010
  PubMed ID: 20628086
   
  
• Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
  Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Tevfik Dorak M
  Mol Hum Reprod. 2010
  PubMed ID: 20587610
   
  
• Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
  van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J
  J Neurochem. 2010
  PubMed ID: 20557428
   
  
• Nuclear receptors in leydig cell gene expression and function.
  Martin LJ, Tremblay JJ
  Biol Reprod. 2010
  PubMed ID: 20375256
   
  
• Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice.
  Krzyzosiak A, Szyszka-Niagolov M, Wietrzych M, Gobaille S, Muramatsu S, Krezel W
  Neuron. 2010
  PubMed ID: 20620876
   
  
• Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
  Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
  Dev Cell. 2010
  PubMed ID: 20412781
   
  
• An atlas of combinatorial transcriptional regulation in mouse and man.
  Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
  Cell. 2010
  PubMed ID: 20211142
   
  
• Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.
  Clugston RD, Zhang W, Alvarez S, de Lera AR, Greer JJ
  Am J Respir Cell Mol Biol. 2010
  PubMed ID: 19448158
   
  
• Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.
  Chen S, Wang K, Wan YJ
  Biochem Pharmacol. 2010
  PubMed ID: 19686701
   
  
• Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.
  Hammock EA, Eagleson KL, Barlow S, Earls LR, Miller DM, Levitt P
  Neural Dev. 2010
  PubMed ID: 21122108
   
  
• Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription.
  Zella LA, Meyer MB, Nerenz RD, Lee SM, Martowicz ML, Pike JW
  Mol Endocrinol. 2010
  PubMed ID: 19897601
   
  
• A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
  Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
  Dev Cell. 2009
  PubMed ID: 20059953
   
  
• Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
  Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
  Am J Hum Genet. 2009
  PubMed ID: 19913121
   
  
• Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.
  Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N
  Liver Int. 2009
  PubMed ID: 19737349
   
  
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
  PLoS Genet. 2009
  PubMed ID: 19851445
   
  
• High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population.
  Mugford JW, Yu J, Kobayashi A, McMahon AP
  Dev Biol. 2009
  PubMed ID: 19591821
   
  
• A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.
  Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD
  J Neurosci. 2009
  PubMed ID: 19741146
   
  
• Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
  Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
  Eur Urol. 2009
  PubMed ID: 19692168
   
  
• Retinoid X receptor beta polymorphisms do not explain functional differences in vitamins D and A response in Antineutrophil cytoplasmic antibody associated vasculitis patients.
  Kälsch AI, Peters A, Buhl B, Breedijk A, Prem K, Schmitt WH, Weiss C, Heeringa P, Kallenberg C, Birck R, Yard BA
  Autoimmunity. 2009
  PubMed ID: 19811264
   
  
• PTEN identified as important risk factor of chronic obstructive pulmonary disease.
  Hosgood HD, Menashe I, He X, Chanock S, Lan Q
  Respir Med. 2009
  PubMed ID: 19625176
   
  
• Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning.
  Uehara M, Yashiro K, Takaoka K, Yamamoto M, Hamada H
  Genes Dev. 2009
  PubMed ID: 19605690
   
  
• A High-Density Association Study of 383 Candidate Genes for Volumetric Bone Density at the Femoral Neck and Lumbar Spine among Older Men.
  Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, for the MrOS Research Group
  J Bone Miner Res. 2009
  PubMed ID: 19453261
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
  Ahn J, Albanes D, Berndt SI, Peters U, Chatterjee N, Freedman ND, Abnet CC, Huang WY, Kibel AS, Crawford ED, Weinstein SJ, Chanock SJ, Schatzkin A, Hayes RB, Prostate, Lung, Colorectal and Ovarian Trial Project Team
  Carcinogenesis. 2009
  PubMed ID: 19255064
   
  
• Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
  Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
  Environ Mol Mutagen. 2009
  PubMed ID: 19170196
   
  
• A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.
  Mascrez B, Ghyselinck NB, Chambon P, Mark M
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19255444
   
  
• Sequential RARbeta and alpha signalling in vivo can induce adult forebrain neural progenitor cells to differentiate into neurons through Shh and FGF signalling pathways.
  Goncalves MB, Agudo M, Connor S, McMahon S, Minger SL, Maden M, Corcoran JP
  Dev Biol. 2009
  PubMed ID: 19100254
   
  
• Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.
  Zhang Z, Hener P, Frossard N, Kato S, Metzger D, Li M, Chambon P
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19188585
   
  
• Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China.
  Andreotti G, Menashe I, Chen J, Chang SC, Rashid A, Gao YT, Han TQ, Sakoda LC, Chanock S, Rosenberg PS, Hsing AW
  Eur J Epidemiol. 2009
  PubMed ID: 19888660
   
  
• Genetic Variability of RXRB, PPARA, and PPARG in Wegener's Granulomatosis.
  Wieczorek S, Knaup S, Gross WL, Epplen JT
  PPAR Res. 2009
  PubMed ID: 19223982
   
  
• Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter.
  Islam MR, Puri S, Rodova M, Magenheimer BS, Maser RL, Calvet JP
  Am J Physiol Renal Physiol. 2008
  PubMed ID: 18922886
   
  
• Insulation of the ubiquitous Rxrb promoter from the cartilage-specific adjacent gene, Col11a2.
  Murai J, Ikegami D, Okamoto M, Yoshikawa H, Tsumaki N
  J Biol Chem. 2008
  PubMed ID: 18682388
   
  
• Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
  Hosgood HD, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q
  Carcinogenesis. 2008
  PubMed ID: 18676680
   
  
• Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.
  Sato Y, Heuckeroth RO
  Dev Biol. 2008
  PubMed ID: 18561907
   
  
• Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
  Lu Y, Dollé ME, Imholz S, Slot RV, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM
  J Lipid Res. 2008
  PubMed ID: 18660489
   
  
• Modular patterning of structure and function of the striatum by retinoid receptor signaling.
  Liao WL, Tsai HC, Wang HF, Chang J, Lu KM, Wu HL, Lee YC, Tsai TF, Takahashi H, Wagner M, Ghyselinck NB, Chambon P, Liu FC
  Proc Natl Acad Sci U S A. 2008
  PubMed ID: 18443282
   
  
• Retinoic acid induces prostatic bud formation.
  Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE
  Dev Dyn. 2008
  PubMed ID: 18393306
   
  
• GUDMAP: the genitourinary developmental molecular anatomy project.
  McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
  J Am Soc Nephrol. 2008
  PubMed ID: 18287559
   
  
• Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China.
  Chang SC, Rashid A, Gao YT, Andreotti G, Shen MC, Wang BS, Han TQ, Zhang BH, Sakoda LC, Leitzmann MF, Chen BE, Rosenberg P, Chen J, Chanock S, Hsing AW
  Carcinogenesis. 2008
  PubMed ID: 18375961
   
  
• Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.
  Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP
  Thromb Haemost. 2008
  PubMed ID: 18217139
   
  
• Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation.
  Brtko J, Rock E, Nezbedova P, Krizanova O, Dvorcakova M, Minet-Quinard R, Farges MC, Ribalta J, Winklhofer-Roob BM, Vasson MP, Macejova D
  Mech Ageing Dev. 2007
  PubMed ID: 17916375
   
  
• A multipotent progenitor domain guides pancreatic organogenesis.
  Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA
  Dev Cell. 2007
  PubMed ID: 17609113
   
  
• Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.
  Hu P, Zhang M, Napoli JL
  Biochim Biophys Acta. 2007
  PubMed ID: 17270348
   
  
• Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors.
  Waxman JS, Yelon D
  Dev Dyn. 2007
  PubMed ID: 17195188
   
  
• Genome-wide atlas of gene expression in the adult mouse brain.
  Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, Boe AF, Boguski MS, Brockway KS, Byrnes EJ, Chen L, Chen L, Chen TM, Chin MC, Chong J, Crook BE, Czaplinska A, Dang CN, Datta S, Dee NR, Desaki AL, Desta T, Diep E, Dolbeare TA, Donelan MJ, Dong HW, Dougherty JG, Duncan BJ, Ebbert AJ, Eichele G, Estin LK, Faber C, Facer BA, Fields R, Fischer SR, Fliss TP, Frensley C, Gates SN, Glattfelder KJ, Halverson KR, Hart MR, Hohmann JG, Howell MP, Jeung DP, Johnson RA, Karr PT, Kawal R, Kidney JM, Knapik RH, Kuan CL, Lake JH, Laramee AR, Larsen KD, Lau C, Lemon TA, Liang AJ, Liu Y, Luong LT, Michaels J, Morgan JJ, Morgan RJ, Mortrud MT, Mosqueda NF, Ng LL, Ng R, Orta GJ, Overly CC, Pak TH, Parry SE, Pathak SD, Pearson OC, Puchalski RB, Riley ZL, Rockett HR, Rowland SA, Royall JJ, Ruiz MJ, Sarno NR, Schaffnit K, Shapovalova NV, Sivisay T, Slaughterbeck CR, Smith SC, Smith KA, Smith BI, Sodt AJ, Stewart NN, Stumpf KR, Sunkin SM, Sutram M, Tam A, Teemer CD, Thaller C, Thompson CL, Varnam LR, Visel A, Whitlock RM, Wohnoutka PE, Wolkey CK, Wong VY, Wood M, Yaylaoglu MB, Young RC, Youngstrom BL, Yuan XF, Zhang B, Zwingman TA, Jones AR
  Nature. 2007
  PubMed ID: 17151600
   
  
• Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.
  Vasků V, Bienertová Vasků J, Pávková Goldbergová M, Vasků A
  Dermatology. 2007
  PubMed ID: 17341859
   
  
• Dietary soy protein isolate modifies hepatic retinoic acid receptor-beta proteins and inhibits their DNA binding activity in rats.
  Xiao CW, Mei J, Huang W, Wood C, L'abbé MR, Gilani GS, Cooke GM, Curran IH
  J Nutr. 2007
  PubMed ID: 17182792
   
  
• Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.
  Vernet N, Dennefeld C, Guillou F, Chambon P, Ghyselinck NB, Mark M
  EMBO J. 2006
  PubMed ID: 17124491
   
  
• A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
  Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA
  Development. 2006
  PubMed ID: 16971476
   
  
• Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis.
  Li M, Hener P, Zhang Z, Kato S, Metzger D, Chambon P
  Proc Natl Acad Sci U S A. 2006
  PubMed ID: 16880407
   
  
• Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.
  Calléja C, Messaddeq N, Chapellier B, Yang H, Krezel W, Li M, Metzger D, Mascrez B, Ohta K, Kagechika H, Endo Y, Mark M, Ghyselinck NB, Chambon P
  Genes Dev. 2006
  PubMed ID: 16751185
   
  
• Towards a proteome-scale map of the human protein-protein interaction network.
  Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M
  Nature. 2005
  PubMed ID: 16189514
   
  
• Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.
  Li M, Messaddeq N, Teletin M, Pasquali JL, Metzger D, Chambon P
  Proc Natl Acad Sci U S A. 2005
  PubMed ID: 16199515
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.
  Roberts MR, Hendrickson A, McGuire CR, Reh TA
  Invest Ophthalmol Vis Sci. 2005
  PubMed ID: 16043864
   
  
• Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.
  Urano A, Endoh M, Wada T, Morikawa Y, Itoh M, Kataoka Y, Taki T, Akazawa H, Nakajima H, Komuro I, Yoshida N, Hayashi Y, Handa H, Kitamura T, Nosaka T
  Mol Cell Biol. 2005
  PubMed ID: 16024815
   
  
• Genomewide linkage analysis identifies novel genetic Loci for lung function in mice.
  Reinhard C, Meyer B, Fuchs H, Stoeger T, Eder G, Rüschendorf F, Heyder J, Nürnberg P, de Angelis MH, Schulz H
  Am J Respir Crit Care Med. 2005
  PubMed ID: 15640362
   
  
• p62, A TFIIH subunit, directly interacts with thyroid hormone receptor and enhances T3-mediated transcription.
  Liu Y, Ando S, Xia X, Yao R, Kim M, Fondell J, Yen PM
  Mol Endocrinol. 2005
  PubMed ID: 15625236
   
  
• Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.
  Feng J, Chen J, Yan J, Jones IR, Craddock N, Cook EH, Goldman D, Heston LL, Sommer SS
  Am J Med Genet B Neuropsychiatr Genet. 2005
  PubMed ID: 15635645
   
  
• Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
  Albers M, Kranz H, Kober I, Kaiser C, Klink M, Suckow J, Kern R, Koegl M
  Mol Cell Proteomics. 2005
  PubMed ID: 15604093
   
  
• Mouse brain organization revealed through direct genome-scale TF expression analysis.
  Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
  Science. 2004
  PubMed ID: 15618518
   
  
• Retinoid X receptors: X-ploring their (patho)physiological functions.
  Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L
  Cell Death Differ. 2004
  PubMed ID: 15608692
   
  
• Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain.
  Puskás LG, Bereczki E, Sántha M, Vigh L, Csanádi G, Spener F, Ferdinandy P, Onochy A, Kitajka K
  Biochimie. 2004
  PubMed ID: 15589691
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Genomic analysis of mouse retinal development.
  Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
  PLoS Biol. 2004
  PubMed ID: 15226823
   
  
• Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.
  Still IH, Vettaikkorumakankauv AK, DiMatteo A, Liang P
  BMC Evol Biol. 2004
  PubMed ID: 15207008
   
  
• Polychlorinated biphenyls suppress thyroid hormone receptor-mediated transcription through a novel mechanism.
  Miyazaki W, Iwasaki T, Takeshita A, Kuroda Y, Koibuchi N
  J Biol Chem. 2004
  PubMed ID: 14985366
   
  
• Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.
  Abe K, Yuzuriha M, Sugimoto M, Ko MS, Brathwaite M, Waeltz P, Nagaraja R
  Mamm Genome. 2004
  PubMed ID: 15112104
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
  PubMed ID: 15057822
   
  
• Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
  Mascrez B, Ghyselinck NB, Watanabe M, Annicotte JS, Chambon P, Auwerx J, Mark M
  EMBO Rep. 2004
  PubMed ID: 14993927
   
  
• The DNA sequence and analysis of human chromosome 6.
  Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S
  Nature. 2003
  PubMed ID: 14574404
   
  
• Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation.
  Svensson S, Ostberg T, Jacobsson M, Norström C, Stefansson K, Hallén D, Johansson IC, Zachrisson K, Ogg D, Jendeberg L
  EMBO J. 2003
  PubMed ID: 12970175
   
  
• Effects of retinoid ligands on RIP140: molecular interaction with retinoid receptors and biological activity.
  Farooqui M, Franco PJ, Thompson J, Kagechika H, Chandraratna RA, Banaszak L, Wei LN
  Biochemistry. 2003
  PubMed ID: 12549917
   
  
• Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.
  Alfaro JM, Fraile B, Lobo MV, Royuela M, Paniagua R, Arenas MI
  J Androl. 2003
  PubMed ID: 12514092
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• Real-time analysis of molecular interaction of retinoid receptors and receptor-interacting protein 140 (RIP140).
  Chen Y, Kerimo A, Khan S, Wei LN
  Mol Endocrinol. 2002
  PubMed ID: 12403842
   
  
• Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.
  Kobayashi H, Spilde TL, Bhatia AM, Buckingham RB, Hembree MJ, Prasadan K, Preuett BL, Imamura M, Gittes GK
  Gastroenterology. 2002
  PubMed ID: 12360493
   
  
• The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.
  Love JD, Gooch JT, Benko S, Li C, Nagy L, Chatterjee VK, Evans RM, Schwabe JW
  J Biol Chem. 2002
  PubMed ID: 11782480
   
  
• The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.
  Brabender J, Danenberg KD, Metzger R, Schneider PM, Lord RV, Groshen S, Tsao-Wei DD, Park J, Salonga D, Hölscher AH, Danenberg PV
  Clin Cancer Res. 2002
  PubMed ID: 11839661
   
  
• Mutation analysis of the retinoid X receptor beta, nuclear-related receptor 1, and peroxisome proliferator-activated receptor alpha genes in schizophrenia and alcohol dependence: possible haplotype association of nuclear-related receptor 1 gene to alcohol
  Ishiguro H, Okubo Y, Ohtsuki T, Yamakawa-Kobayashi K, Arinami T
  Am J Med Genet. 2002
  PubMed ID: 11840500
   
  
• External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.
  Ogino Y, Suzuki K, Haraguchi R, Satoh Y, Dolle P, Yamada G
  Ann N Y Acad Sci. 2001
  PubMed ID: 11795391
   
  
• Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.
  Mascrez B, Mark M, Krezel W, Dupé V, LeMeur M, Ghyselinck NB, Chambon P
  Development. 2001
  PubMed ID: 11493527
   
  
• Ligand-dependent formation of retinoid receptors, receptor-interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140.
  Wei LN, Farooqui M, Hu X
  J Biol Chem. 2001
  PubMed ID: 11278635
   
  
• Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.
  Mori M, Ghyselinck NB, Chambon P, Mark M
  Invest Ophthalmol Vis Sci. 2001
  PubMed ID: 11328745
   
  
• Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.
  Billas IM, Moulinier L, Rochel N, Moras D
  J Biol Chem. 2001
  PubMed ID: 11053444
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
  Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
  Genome Res. 2000
  PubMed ID: 11076861
   
  
• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
  Genome Res. 2000
  PubMed ID: 11042159
   
  
• Interactions between the prohormone convertase 2 promoter and the thyroid hormone receptor.
  Li QL, Jansen E, Brent GA, Naqvi S, Wilber JF, Friedman TC
  Endocrinology. 2000
  PubMed ID: 10965896
   
  
• Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
  Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
  Proc Natl Acad Sci U S A. 2000
  PubMed ID: 10922068
   
  
• Connexin43 gene expression and regulation in the rodent seminiferous epithelium.
  Batias C, Siffroi JP, Fénichel P, Pointis G, Segretain D
  J Histochem Cytochem. 2000
  PubMed ID: 10820153
   
  
• Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.
  Ulven SM, Gundersen TE, Weedon MS, Landaas VO, Sakhi AK, Fromm SH, Geronimo BA, Moskaug JO, Blomhoff R
  Dev Biol. 2000
  PubMed ID: 10753524
   
  
• Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
  Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
  Development. 2000
  PubMed ID: 10725249
   
  
• The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression.
  Lee YK, Dell H, Dowhan DH, Hadzopoulou-Cladaras M, Moore DD
  Mol Cell Biol. 2000
  PubMed ID: 10594021
   
  
• Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells.
  Chen F, Figueroa DJ, Marmorstein AD, Zhang Q, Petrukhin K, Caskey CT, Austin CP
  Proc Natl Acad Sci U S A. 1999
  PubMed ID: 10611353
   
  
• Characterization of receptor-interacting protein 140 in retinoid receptor activities.
  Lee CH, Wei LN
  J Biol Chem. 1999
  PubMed ID: 10531331
   
  
• Retinoic acid signaling is necessary for the development of the organ of Corti.
  Raz Y, Kelley MW
  Dev Biol. 1999
  PubMed ID: 10452855
   
  
• A genetic dissection of the retinoid signalling pathway in the mouse.
  Mark M, Ghyselinck NB, Wendling O, Dupé V, Mascrez B, Kastner P, Chambon P
  Proc Nutr Soc. 1999
  PubMed ID: 10604193
   
  
• Dorsal and ventral rentinoic territories defined by retinoic acid synthesis, break-down and nuclear receptor expression.
  McCaffery P, Wagner E, O'Neil J, Petkovich M, Dräger UC
  Mech Dev. 1999
  PubMed ID: 10490294
   
  
• The structure of the nuclear hormone receptors.
  Kumar R, Thompson EB
  Steroids. 1999
  PubMed ID: 10406480
   
  
• Identification of a novel DNA binding site for nuclear orphan receptor OR1.
  Feltkamp D, Wiebel FF, Alberti S, Gustafsson JA
  J Biol Chem. 1999
  PubMed ID: 10187832
   
  
• Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.
  Zhang QY
  Biochem Biophys Res Commun. 1999
  PubMed ID: 10079186
   
  
• Differential regulation of ligand-dependent and ligand-independent functions of the mouse retinoid X receptor beta by alternative splicing.
  Fujita A, Mitsuhashi T
  Biochem Biophys Res Commun. 1999
  PubMed ID: 10049761
   
  
• Retinoid X receptors are essential for early mouse development and placentogenesis.
  Wendling O, Chambon P, Mark M
  Proc Natl Acad Sci U S A. 1999
  PubMed ID: 9892670
   
  
• High-efficiency full-length cDNA cloning.
  Carninci P, Hayashizaki Y
  Methods Enzymol. 1999
  PubMed ID: 10349636
   
  
• Retinoids and adipose tissues: metabolism, cell differentiation and gene expression.
  Villarroya F, Giralt M, Iglesias R
  Int J Obes Relat Metab Disord. 1999
  PubMed ID: 10094571
   
  
• An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.
  Chiang MY, Misner D, Kempermann G, Schikorski T, Giguère V, Sucov HM, Gage FH, Stevens CF, Evans RM
  Neuron. 1998
  PubMed ID: 9883728
   
  
• The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.
  Mascrez B, Mark M, Dierich A, Ghyselinck NB, Kastner P, Chambon P
  Development. 1998
  PubMed ID: 9806918
   
  
• Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.
  Barros AC, Erway LC, Krezel W, Curran T, Kastner P, Chambon P, Forrest D
  Neuroreport. 1998
  PubMed ID: 9804293
   
  
• The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
  Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA
  J Clin Invest. 1998
  PubMed ID: 9727070
   
  
• A regulatory role for RIP140 in nuclear receptor activation.
  Treuter E, Albrektsen T, Johansson L, Leers J, Gustafsson JA
  Mol Endocrinol. 1998
  PubMed ID: 9626662
   
  
• Characterization of Brx, a novel Dbl family member that modulates estrogen receptor action.
  Rubino D, Driggers P, Arbit D, Kemp L, Miller B, Coso O, Pagliai K, Gray K, Gutkind S, Segars J
  Oncogene. 1998
  PubMed ID: 9627117
   
  
• Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear.
  Romand R, Sapin V, Dollé P
  J Comp Neurol. 1998
  PubMed ID: 9548551
   
  
• Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.
  Krezel W, Ghyselinck N, Samad TA, Dupé V, Kastner P, Borrelli E, Chambon P
  Science. 1998
  PubMed ID: 9452386
   
  
• Functional specificity of the two retinoic acid receptor RAR and RXR families in myogenesis.
  Alric S, Froeschlé A, Piquemal D, Carnac G, Bonnieu A
  Oncogene. 1998
  PubMed ID: 9464546
   
  
• Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes.
  Kastner P, Messaddeq N, Mark M, Wendling O, Grondona JM, Ward S, Ghyselinck N, Chambon P
  Development. 1997
  PubMed ID: 9428411
   
  
• Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.
  Chiba H, Clifford J, Metzger D, Chambon P
  J Cell Biol. 1997
  PubMed ID: 9348290
   
  
• TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1.
  Takeshita A, Cardona GR, Koibuchi N, Suen CS, Chin WW
  J Biol Chem. 1997
  PubMed ID: 9346901
   
  
• Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
  Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S
  Gene. 1997
  PubMed ID: 9373149
   
  
• Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.
  Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM
  Cell. 1997
  PubMed ID: 9267036
   
  
• The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.
  Tian K, Norris AW, Lin CL, Li E
  Biochemistry. 1997
  PubMed ID: 9153406
   
  
• Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development.
  Xu XC, Sozzi G, Lee JS, Lee JJ, Pastorino U, Pilotti S, Kurie JM, Hong WK, Lotan R
  J Natl Cancer Inst. 1997
  PubMed ID: 9150186
   
  
• Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.
  Gaemers IC, van Pelt AM, van der Saag PT, Hoogerbrugge JW, Themmen AP, de Rooij DG
  Endocrinology. 1997
  PubMed ID: 9075714
   
  
• Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.
  Sapin V, Ward SJ, Bronner S, Chambon P, Dollé P
  Dev Dyn. 1997
  PubMed ID: 9022057
   
  
• RIP 140 enhances nuclear receptor-dependent transcription in vivo in yeast.
  Joyeux A, Cavaillès V, Balaguer P, Nicolas JC
  Mol Endocrinol. 1997
  PubMed ID: 9013766
   
  
• Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development.
  Kastner P, Mark M, Ghyselinck N, Krezel W, Dupé V, Grondona JM, Chambon P
  Development. 1997
  PubMed ID: 9053308
   
  
• Myeloid differentiation is impaired in transgenic mice with targeted expression of a dominant negative form of retinoid X receptor beta.
  Sunaga S, Maki K, Lagasse E, Blanco JC, Ozato K, Miyazaki J, Ikuta K
  Br J Haematol. 1997
  PubMed ID: 9012684
   
  
• The mouse col11a2 gene. Some transcripts from the adjacent rxr-beta gene extend into the col11a2 gene.
  Vandenberg P, Vuoristo MM, Ala-Kokko L, Prockop DJ
  Matrix Biol. 1996
  PubMed ID: 8981332
   
  
• Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3.
  Nicoll DA, Quednau BD, Qui Z, Xia YR, Lusis AJ, Philipson KD
  J Biol Chem. 1996
  PubMed ID: 8798769
   
  
• Normalization and subtraction: two approaches to facilitate gene discovery.
  Bonaldo MF, Lennon G, Soares MB
  Genome Res. 1996
  PubMed ID: 8889548
   
  
• Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage.
  Tsumaki N, Kimura T, Matsui Y, Nakata K, Ochi T
  J Cell Biol. 1996
  PubMed ID: 8830784
   
  
• Limited degradation of retinoid X receptor by calpain.
  Matsushima-Nishiwaki R, Shidoji Y, Nishiwaki S, Moriwaki H, Muto Y
  Biochem Biophys Res Commun. 1996
  PubMed ID: 8780715
   
  
• Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex.
  Kasahara M, Hayashi M, Tanaka K, Inoko H, Sugaya K, Ikemura T, Ishibashi T
  Proc Natl Acad Sci U S A. 1996
  PubMed ID: 8799160
   
  
• RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.
  Krezel W, Dupé V, Mark M, Dierich A, Kastner P, Chambon P
  Proc Natl Acad Sci U S A. 1996
  PubMed ID: 8799145
   
  
• Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.
  Welch CL, Xia YR, Shechter I, Farese R, Mehrabian M, Mehdizadeh S, Warden CH, Lusis AJ
  J Lipid Res. 1996
  PubMed ID: 8827514
   
  
• A decade of molecular biology of retinoic acid receptors.
  Chambon P
  FASEB J. 1996
  PubMed ID: 8801176
   
  
• RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells.
  Horn V, Minucci S, Ogryzko VV, Adamson ED, Howard BH, Levin AA, Ozato K
  FASEB J. 1996
  PubMed ID: 8801169
   
  
• Localization of mouse peroxisome proliferator-activated receptor delta (Ppard) on chromosome 17 near colipase (Clps).
  Cohen RD, Welch C, Xia Y, Lusis AJ, Reue K
  Mamm Genome. 1996
  PubMed ID: 8672143
   
  
• Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.
  May M, Mengus G, Lavigne AC, Chambon P, Davidson I
  EMBO J. 1996
  PubMed ID: 8670810
   
  
• Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones.
  Poole TM, Drinkwater NR
  Proc Natl Acad Sci U S A. 1996
  PubMed ID: 8650181
   
  
• Differential 9-cis-retinoic acid-dependent transcriptional activation by murine retinoid X receptor alpha (RXR alpha) and RXR beta. Role of cell type and RXR domains.
  Hallenbeck PL, Minucci S, Lippoldt R, Phyillaier M, Horn V, Ozato K, Nikodem VM
  J Biol Chem. 1996
  PubMed ID: 8631847
   
  
• Physical mapping of the Ring1, Ring2, Ke6, Ke4, Rxrb, Col11a2, and RT1.Hb genes in the rat major histocompatibility complex.
  Walter L, Fischer K, Günther E
  Immunogenetics. 1996
  PubMed ID: 8662089
   
  
• Abnormal spermatogenesis in RXR beta mutant mice.
  Kastner P, Mark M, Leid M, Gansmuller A, Chin W, Grondona JM, Décimo D, Krezel W, Dierich A, Chambon P
  Genes Dev. 1996
  PubMed ID: 8557197
   
  
• Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligan
  Roy B, Taneja R, Chambon P
  Mol Cell Biol. 1995
  PubMed ID: 8524212
   
  
• Sequence and characterization of a coactivator for the steroid hormone receptor superfamily.
  Oñate SA, Tsai SY, Tsai MJ, O'Malley BW
  Science. 1995
  PubMed ID: 7481822
   
  
• Involvement of retinoic acid receptor alpha in the stimulation of tissue-type plasminogen-activator gene expression in human endothelial cells.
  Kooistra T, Lansink M, Arts J, Sitter T, Toet K
  Eur J Biochem. 1995
  PubMed ID: 7556191
   
  
• Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.
  Harrison SM, Dunwoodie SL, Arkell RM, Lehrach H, Beddington RS
  Development. 1995
  PubMed ID: 7671812
   
  
• Unique response pathways are established by allosteric interactions among nuclear hormone receptors.
  Forman BM, Umesono K, Chen J, Evans RM
  Cell. 1995
  PubMed ID: 7758108
   
  
• A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.
  Perlmann T, Jansson L
  Genes Dev. 1995
  PubMed ID: 7705655
   
  
• Differential expression of an acidic domain in the amino-terminal propeptide of mouse pro-alpha 2(XI) collagen by complex alternative splicing.
  Tsumaki N, Kimura T
  J Biol Chem. 1995
  PubMed ID: 7836472
   
  
• A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells.
  Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y
  Mol Cell Biol. 1995
  PubMed ID: 7823919
   
  
• Physical mapping of the retinoid X receptor B gene in mouse and human.
  Nagata T, Weiss EH, Abe K, Kitagawa K, Ando A, Yara-Kikuti Y, Seldin MF, Ozato K, Inoko H, Taketo M
  Immunogenetics. 1995
  PubMed ID: 7806300
   
  
• An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.
  Zanaria E, Muscatelli F, Bardoni B, Strom TM, Guioli S, Guo W, Lalli E, Moser C, Walker AP, McCabe ER
  Nature. 1994
  PubMed ID: 7990953
   
  
• The retinoid receptors.
  Pemrick SM, Lucas DA, Grippo JF
  Leukemia. 1994
  PubMed ID: 7967725
   
  
• Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.
  Rochette-Egly C, Lutz Y, Pfister V, Heyberger S, Scheuer I, Chambon P, Gaub MP
  Biochem Biophys Res Commun. 1994
  PubMed ID: 7980510
   
  
• Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.
  van Deursen J, Ruitenbeek W, Heerschap A, Jap P, ter Laak H, Wieringa B
  Proc Natl Acad Sci U S A. 1994
  PubMed ID: 8090775
   
  
• Expression of nuclear retinoic acid receptors during mouse odontogenesis.
  Bloch-Zupan A, Décimo D, Loriot M, Mark MP, Ruch JV
  Differentiation. 1994
  PubMed ID: 7988794
   
  
• Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.
  Jonk LJ, de Jonge ME, Pals CE, Wissink S, Vervaart JM, Schoorlemmer J, Kruijer W
  Mech Dev. 1994
  PubMed ID: 7947324
   
  
• The mouse Rxrb gene encoding RXR beta: genomic organization and two mRNA isoforms generated by alternative splicing of transcripts initiated from CpG island promoters.
  Nagata T, Kanno Y, Ozato K, Taketo M
  Gene. 1994
  PubMed ID: 8194750
   
  
• RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.
  Sucov HM, Dyson E, Gumeringer CL, Price J, Chien KR, Evans RM
  Genes Dev. 1994
  PubMed ID: 7926783
   
  
• Chromosomal localization of the human retinoid X receptors.
  Almasan A, Mangelsdorf DJ, Ong ES, Wahl GM, Evans RM
  Genomics. 1994
  PubMed ID: 8034312
   
  
• Analysis of the factors involved in the retinoic acid-induced differentiation of a retinoid-hypersensitive embryonal carcinoma cell mutant.
  Dietrich JM, McCormick PJ
  Exp Cell Res. 1994
  PubMed ID: 8299717
   
  
• Developmental expression of murine retinoid X receptor (RXR) genes.
  Dollé P, Fraulob V, Kastner P, Chambon P
  Mech Dev. 1994
  PubMed ID: 8199055
   
  
• Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
  Maruyama K, Sugano S
  Gene. 1994
  PubMed ID: 8125298
   
  
• Retinoic acid-response elements with a highly repetitive structure isolated by immuno-selection from genomic DNA.
  Rudert F, Gronemeyer H
  J Steroid Biochem Mol Biol. 1993
  PubMed ID: 8664160
   
  
• Mapping of RXRB to human chromosome 6p21.3.
  Fitzgibbon J, Gillett GT, Woodward KJ, Boyle JM, Wolfe J, Povey S
  Ann Hum Genet. 1993
  PubMed ID: 8257090
   
  
• Cloning and chromosome mapping of human retinoid X receptor beta: selective amino acid sequence conservation of a nuclear hormone receptor in mammals.
  Fleischhauer K, McBride OW, DiSanto JP, Ozato K, Yang SY
  Hum Genet. 1993
  PubMed ID: 8381386
   
  
• Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.
  
  Cell. 1992
  PubMed ID: 1330328
   
  
• Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma.
  Hoopes CW, Taketo M, Ozato K, Liu Q, Howard TA, Linney E, Seldin MF
  Genomics. 1992
  PubMed ID: 1358808
   
  
• Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.
  Berrodin TJ, Marks MS, Ozato K, Linney E, Lazar MA
  Mol Endocrinol. 1992
  PubMed ID: 1331778
   
  
• Isolation of a full-length cDNA clone encoding a N-terminally variant form of the human retinoid X receptor beta.
  Fleischhauer K, Park JH, DiSanto JP, Marks M, Ozato K, Yang SY
  Nucleic Acids Res. 1992
  PubMed ID: 1315958
   
  
• H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.
  Marks MS, Hallenbeck PL, Nagata T, Segars JH, Appella E, Nikodem VM, Ozato K
  EMBO J. 1992
  PubMed ID: 1314168
   
  
• Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.
  Mangelsdorf DJ, Borgmeyer U, Heyman RA, Zhou JY, Ong ES, Oro AE, Kakizuka A, Evans RM
  Genes Dev. 1992
  PubMed ID: 1312497
   
  
• Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.
  Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Garnier JM, Mader S
  Cell. 1992
  PubMed ID: 1310259
   
  
• The human cDNA sequence homologous to the mouse MHC class I promoter-binding protein gene contains four additional codons in lymphocytes.
  Epplen C, Epplen JT
  Mamm Genome. 1992
  PubMed ID: 1514958
   
  
• RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements.
  Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Näär AM, Kim SY, Boutin JM, Glass CK, Rosenfeld MG
  Cell. 1991
  PubMed ID: 1662118
   
  
• H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element.
  Hamada K, Gleason SL, Levi BZ, Hirschfeld S, Appella E, Ozato K
  Proc Natl Acad Sci U S A. 1989
  PubMed ID: 2554307
   
  

Relevant resources:

Comment on this Page
Privacy Statement  |   Copyright, Warranty & Disclaimer  |   Contact Us
Copyright © 2001-2011, T1DBase | Version 4.8 | PMID:20937630
Printed on Fri February 10, 2012