• About T1DBase
• Regions
  • Human T1D Regions
  • Mouse T1D Regions
    • Linkage Regions
    • Orthologous Regions
  • Rat T1D Regions
    • Linkage Regions
    • Orthologous Regions
    • QTL Regions
• Genome Browser
  • Human GBrowse
  • Mouse GBrowse
  • Rat GBrowse
• Tools
  • Gene Dossier
  • Beta Cell Gene Atlas
  • Batch Query
  • Sequence Search
  • HaemAtlas Search
  • Mouse Strain Search
• Data
  • Poster Pages
  • Downloads
  • Data Submission
• Help
  • FAQ
  • T1DBase Tutorial
• Contact Us

• Page Sections
  • Summary
  • Regions of Interest Overlapping this feature
  • Gene Overview
  • Beta Cell Gene Atlas
  • Tissue Expression
  • HaemAtlas Expression
  • Interactions
  • Cross-Reference to Pathways and GO Terms
  • Publications
  • Model Organism Phenotype Links
  • External Links
  • External resources (dkCOIN)

RPL6

Gene Description:   ribosomal protein L6 Synonyms:   Taxreb107, L6, SHUJUN-2, RPL6, MGC117949, TAXREB107, TXREB1, Rpl6 Orthologs:   Human RPL6 (protein-coding), Mouse Rpl6 (protein-coding)   Sources Sources Human-Mouse: MGD Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
12q24.12	Human	chr12:111287726..113238728	1.95	126	rs3184504

Other Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Human 12q24.12 Orthologous Region	Mouse	chr5:121453514..122577854	1.12	22

(Human) GRCh37 - chr12:112842994..112856642 (13.65 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr5:121654490..121659250 (4.76 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas no data               no data no data no data no data no data

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for RPL6: The RPL6 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs RPL6   GABARAP   IntAct  empirical  20562859  RPL6   GABARAPL2   IntAct  empirical  20562859  RPL6   ESR1   IntAct  empirical  21182205  RPL6   FGF2   HPRD, BioGRID  empirical  9826564  RPL6   RPGRIP1L   IntAct  empirical  21565611  RPL6   ITGB3BP   IntAct  empirical  16169070  RPL6   GABARAPL1   IntAct  empirical  20562859  RPL6   EIF6   HPRD  empirical  16169070  RPL6   ARRB1   IntAct  empirical  17620599  RPL6   ARRB2   IntAct  empirical  17620599  RPL6   NFKB2   HPRD, MINT, IntAct, BioGRID  empirical  14743216  RPL6   PPP2R2B   IntAct  empirical  19156129  RPL6   RPL29   HPRD  empirical  6468376  RPL6   STAU1   HPRD, IntAct  empirical  15121898  15303970  RPL6   UBC   BioGRID  empirical  16196087  RPL6   YWHAB   IntAct  empirical  16635246  RPL6   YWHAZ   MINT  empirical  15161933  RPL6   MAP1LC3A   IntAct  empirical  20562859  RPL6   MAP3K14   HPRD, MINT, IntAct  empirical  14743216

View all

KEGG Network: 1   Ribosome Human - 3010 Mouse - 3010

Biocarta: None available   None available.

Reactome: 18   3 -UTR-mediated translational regulation REACT_1762 Cap-dependent Translation Initiation REACT_2099 Diabetes pathways REACT_15380 Eukaryotic Translation Elongation REACT_1477 Eukaryotic Translation Initiation REACT_2159 Eukaryotic Translation Termination REACT_1986 Formation of a pool of free 40S subunits REACT_1797 Gene Expression REACT_71 GTP hydrolysis and joining of the 60S ribosomal subunit REACT_2085 Influenza Viral RNA Transcription and Replication REACT_6152 Insulin Synthesis and Processing REACT_15550 L13a-mediated translational silencing of Ceruloplasmin expression REACT_79 Metabolism of proteins REACT_17015 Peptide chain elongation REACT_1404 Regulation of beta-cell development REACT_13698 Regulation of gene expression in beta cells REACT_13819 Translation REACT_1014 Viral mRNA Translation REACT_9491

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 19   DNA binding GO:0003677 RNA binding GO:0003723 Structural constituent of ribosome GO:0003735 Intracellular GO:0005622 Cytosol GO:0005829 Ribosome GO:0005840 Regulation of transcription, DNA-dependent GO:0006355 Translation GO:0006412 Translational elongation GO:0006414 Translational termination GO:0006415 Gene expression GO:0010467 Viral reproduction GO:0016032 RNA metabolic process GO:0016070 MRNA metabolic process GO:0016071 Viral infectious cycle GO:0019058 Viral transcription GO:0019083 Cytosolic large ribosomal subunit GO:0022625 Endocrine pancreas development GO:0031018 Cellular protein metabolic process GO:0044267

	KEGG Network: 1 Ribosome Human - 3010 Mouse - 3010
	Biocarta: None available
	Reactome: 18 3 -UTR-mediated translational regulation REACT_1762 Cap-dependent Translation Initiation REACT_2099 Diabetes pathways REACT_15380 Eukaryotic Translation Elongation REACT_1477 Eukaryotic Translation Initiation REACT_2159 Eukaryotic Translation Termination REACT_1986 Formation of a pool of free 40S subunits REACT_1797 Gene Expression REACT_71 GTP hydrolysis and joining of the 60S ribosomal subunit REACT_2085 Influenza Viral RNA Transcription and Replication REACT_6152 Insulin Synthesis and Processing REACT_15550 L13a-mediated translational silencing of Ceruloplasmin expression REACT_79 Metabolism of proteins REACT_17015 Peptide chain elongation REACT_1404 Regulation of beta-cell development REACT_13698 Regulation of gene expression in beta cells REACT_13819 Translation REACT_1014 Viral mRNA Translation REACT_9491
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 19 DNA binding GO:0003677 RNA binding GO:0003723 Structural constituent of ribosome GO:0003735 Intracellular GO:0005622 Cytosol GO:0005829 Ribosome GO:0005840 Regulation of transcription, DNA-dependent GO:0006355 Translation GO:0006412 Translational elongation GO:0006414 Translational termination GO:0006415 Gene expression GO:0010467 Viral reproduction GO:0016032 RNA metabolic process GO:0016070 MRNA metabolic process GO:0016071 Viral infectious cycle GO:0019058 Viral transcription GO:0019083 Cytosolic large ribosomal subunit GO:0022625 Endocrine pancreas development GO:0031018 Cellular protein metabolic process GO:0044267

Type 1 Diabetes Publications: 1

• Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
  Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C, Genetics of Type 1 Diabetes in Finland, Simmonds MJ, Heward JM, Gough SC, Wellcome Trust Case Control Consortium, Dunger DB, Wicker LS, Clayton DG
  Nat Genet. 2007
  PubMed ID: 17554260
   
  

Publications: 53

• Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.
  Wu C, Hu Z, He Z, Jia W, Wang F, Zhou Y, Liu Z, Zhan Q, Liu Y, Yu D, Zhai K, Chang J, Qiao Y, Jin G, Liu Z, Shen Y, Guo C, Fu J, Miao X, Tan W, Shen H, Ke Y, Zeng Y, Wu T, Lin D
  Nat Genet. 2011
  PubMed ID: 21642993
   
  
• Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
  Kato N, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ, Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhou X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhang X, Wong TY, Han BG, Kobayashi S, Ogihara T, Zhu D, Iwai N, Wu JY, Teo YY, Tai ES, Cho YS, He J
  Nat Genet. 2011
  PubMed ID: 21572416
   
  
• Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.
  Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Xue S, Ishijima J, Shiroishi T, Barna M
  Cell. 2011
  PubMed ID: 21529712
   
  
• Initial characterization of the human central proteome.
  Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
  BMC Syst Biol. 2011
  PubMed ID: 21269460
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Ribosomal protein L6 promotes growth and cell cycle progression through upregulating cyclin E in gastric cancer cells.
  Gou Y, Shi Y, Zhang Y, Nie Y, Wang J, Song J, Jin H, He L, Gao L, Qiao L, Wu K, Fan D
  Biochem Biophys Res Commun. 2010
  PubMed ID: 20171175
   
  
• Lysine acetylation targets protein complexes and co-regulates major cellular functions.
  Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
  Science. 2009
  PubMed ID: 19608861
   
  
• Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
  Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
  Anal Chem. 2009
  PubMed ID: 19413330
   
  
• Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
  Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
  Genome Res. 2008
  PubMed ID: 18799693
   
  
• Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
  Yu LR, Zhu Z, Chan KC, Issaq HJ, Dimitrov DS, Veenstra TD
  J Proteome Res. 2007
  PubMed ID: 17924679
   
  
• The consensus coding sequences of human breast and colorectal cancers.
  Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE
  Science. 2006
  PubMed ID: 16959974
   
  
• The finished DNA sequence of human chromosome 12.
  Scherer SE, Muzny DM, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Montgomery KT, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Lovering RC, Wheeler DA, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clerc-Blankenburg KP, Davis C, Delgado O, Dinh HH, Draper H, Gonzalez-Garay ML, Havlak P, Jackson LR, Jacob LS, Kelly SH, Li L, Li Z, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Pasternak S, Perez LM, Plopper FJ, Santibanez J, Shen H, Tabor PE, Verduzco D, Waldron L, Wang Q, Williams GA, Zhang J, Zhou J, Allen CC, Amin AG, Anyalebechi V, Bailey M, Barbaria JA, Bimage KE, Bryant NP, Burch PE, Burkett CE, Burrell KL, Calderon E, Cardenas V, Carter K, Casias K, Cavazos I, Cavazos SR, Ceasar H, Chacko J, Chan SN, Chavez D, Christopoulos C, Chu J, Cockrell R, Cox CD, Dang M, Dathorne SR, David R, Davis CM, Davy-Carroll L, Deshazo DR, Donlin JE, D'Souza L, Eaves KA, Egan A, Emery-Cohen AJ, Escotto M, Flagg N, Forbes LD, Gabisi AM, Garza M, Hamilton C, Henderson N, Hernandez O, Hines S, Hogues ME, Huang M, Idlebird DG, Johnson R, Jolivet A, Jones S, Kagan R, King LM, Leal B, Lebow H, Lee S, LeVan JM, Lewis LC, London P, Lorensuhewa LM, Loulseged H, Lovett DA, Lucier A, Lucier RL, Ma J, Madu RC, Mapua P, Martindale AD, Martinez E, Massey E, Mawhiney S, Meador MG, Mendez S, Mercado C, Mercado IC, Merritt CE, Miner ZL, Minja E, Mitchell T, Mohabbat F, Mohabbat K, Montgomery B, Moore N, Morris S, Munidasa M, Ngo RN, Nguyen NB, Nickerson E, Nwaokelemeh OO, Nwokenkwo S, Obregon M, Oguh M, Oragunye N, Oviedo RJ, Parish BJ, Parker DN, Parrish J, Parks KL, Paul HA, Payton BA, Perez A, Perrin W, Pickens A, Primus EL, Pu LL, Puazo M, Quiles MM, Quiroz JB, Rabata D, Reeves K, Ruiz SJ, Shao H, Sisson I, Sonaike T, Sorelle RP, Sutton AE, Svatek AF, Svetz LA, Tamerisa KS, Taylor TR, Teague B, Thomas N, Thorn RD, Trejos ZY, Trevino BK, Ukegbu ON, Urban JB, Vasquez LI, Vera VA, Villasana DM, Wang L, Ward-Moore S, Warren JT, Wei X, White F, Williamson AL, Wleczyk R, Wooden HS, Wooden SH, Yen J, Yoon L, Yoon V, Zorrilla SE, Nelson D, Kucherlapati R, Weinstock G, Gibbs RA, Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
  Nature. 2006
  PubMed ID: 16541075
   
  
• A human protein-protein interaction network: a resource for annotating the proteome.
  Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
  Cell. 2005
  PubMed ID: 16169070
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• Nucleolar proteome dynamics.
  Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
  Nature. 2005
  PubMed ID: 15635413
   
  
• Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
  Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
  Nat Methods. 2004
  PubMed ID: 15782199
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
  Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G
  Nat Cell Biol. 2004
  PubMed ID: 14743216
   
  
• The molecular mechanics of eukaryotic translation.
  Kapp LD, Lorsch JR
  Annu Rev Biochem. 2004
  PubMed ID: 15189156
   
  
• The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs.
  Villacé P, Marión RM, Ortín J
  Nucleic Acids Res. 2004
  PubMed ID: 15121898
   
  
• Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
  Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 14610273
   
  
• Identification of Taxreb107 as a lactogenic hormone responsive gene in mammary epithelial cells.
  Wittlin S, Sutherland KD, Visvader JE, Lindeman GJ
  Biochim Biophys Acta. 2003
  PubMed ID: 14572897
   
  
• Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control.
  Mazumder B, Sampath P, Seshadri V, Maitra RK, DiCorleto PE, Fox PL
  Cell. 2003
  PubMed ID: 14567916
   
  
• Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing.
  Odintsova TI, Müller EC, Ivanov AV, Egorov TA, Bienert R, Vladimirov SN, Kostka S, Otto A, Wittmann-Liebold B, Karpova GG
  J Protein Chem. 2003
  PubMed ID: 12962325
   
  
• [Differential expression of RPL6/Taxreb107 in drug resistant gastric cancer cell line SGC7901/ADR and its correlation with multiple-drug resistance]
  Du JP, Jin XH, Shi YQ, Cao YX, Zhao YQ, Liu CJ, Yin F, Hu WH, Chen BJ, Qiao TD, Fan DM
  Zhonghua Zhong Liu Za Zhi. 2003
  PubMed ID: 12678981
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• Cloning of mouse genomic ribosomal protein L6 gene and analysis of its promoter.
  Wang J, Yang X, Zhou P, Han H
  Biochim Biophys Acta. 2002
  PubMed ID: 12031506
   
  
• A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation.
  Pfisterer P, Ehlermann J, Hegen M, Schorle H
  J Biol Chem. 2002
  PubMed ID: 11741941
   
  
• Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.
  Jäkel S, Mingot JM, Schwarzmaier P, Hartmann E, Görlich D
  EMBO J. 2002
  PubMed ID: 11823430
   
  
• Directed proteomic analysis of the human nucleolus.
  Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI
  Curr Biol. 2002
  PubMed ID: 11790298
   
  
• Isolation and characterization of chicken TaxREB107, a putative DNA binding protein abundantly expressed in muscle.
  Thomson SR, Johnson SE
  Gene. 2001
  PubMed ID: 11707324
   
  
• A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.
  Uechi T, Tanaka T, Kenmochi N
  Genomics. 2001
  PubMed ID: 11401437
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
  Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
  Genome Res. 2000
  PubMed ID: 11076861
   
  
• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
  Genome Res. 2000
  PubMed ID: 11042159
   
  
• cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.
  Ye Z, Connor JR
  Biochem Biophys Res Commun. 2000
  PubMed ID: 10944468
   
  
• Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
  Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
  Proc Natl Acad Sci U S A. 2000
  PubMed ID: 10922068
   
  
• The human ribosomal protein L6 gene in a critical region for Noonan syndrome.
  Kenmochi N, Yoshihama M, Higa S, Tanaka T
  J Hum Genet. 2000
  PubMed ID: 11043511
   
  
• High-efficiency full-length cDNA cloning.
  Carninci P, Hayashizaki Y
  Methods Enzymol. 1999
  PubMed ID: 10349636
   
  
• Intracellular association of FGF-2 with the ribosomal protein L6/TAXREB107.
  Shen B, Arese M, Gualandris A, Rifkin DB
  Biochem Biophys Res Commun. 1998
  PubMed ID: 9826564
   
  
• Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
  Ko MS, Threat TA, Wang X, Horton JH, Cui Y, Wang X, Pryor E, Paris J, Wells-Smith J, Kitchen JR, Rowe LB, Eppig J, Satoh T, Brant L, Fujiwara H, Yotsumoto S, Nakashima H
  Hum Mol Genet. 1998
  PubMed ID: 9811942
   
  
• A map of 75 human ribosomal protein genes.
  Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC
  Genome Res. 1998
  PubMed ID: 9582194
   
  
• Refined genetic mapping of the darier locus to a <1-cM region of chromosome 12q24.1, and construction of a complete, high-resolution P1 artificial chromosome/bacterial artificial chromosome contig of the critical region.
  Monk S, Sakuntabhai A, Carter SA, Bryce SD, Cox R, Harrington L, Levy E, Ruiz-Perez VL, Katsantoni E, Kodvawala A, Munro CS, Burge S, Larrègue M, Nagy G, Rees JL, Lathrop M, Monaco AP, Strachan T, Hovnanian A
  Am J Hum Genet. 1998
  PubMed ID: 9529352
   
  
• Structure and evolution of mammalian ribosomal proteins.
  Wool IG, Chan YL, Glück A
  Biochem Cell Biol. 1995
  PubMed ID: 8722009
   
  
• The mouse homologue of the HTLV-I tax responsive element binding protein TAXREB107 is a highly conserved gene which may regulate some basal cellular functions.
  Nacken W, Klempt M, Sorg C
  Biochim Biophys Acta. 1995
  PubMed ID: 7537974
   
  
• Construction of a human full-length cDNA bank.
  Kato S, Sekine S, Oh SW, Kim NS, Umezawa Y, Abe N, Yokoyama-Kobayashi M, Aoki T
  Gene. 1994
  PubMed ID: 7821789
   
  
• Isolation of a cDNA whose expression is markedly increased in malignantly transformed FRTL cells and neoplastic human thyroid tissues.
  Ohta K, Endo T, Gunji K, Onaya T
  J Mol Endocrinol. 1994
  PubMed ID: 8185817
   
  
• Sequence of a cDNA encoding human ribosomal protein L26 and of a cDNA probably encoding human ribosomal protein L6.
  Zaman GJ
  Nucleic Acids Res. 1993
  PubMed ID: 8479925
   
  
• Isolation of a cDNA clone encoding DNA-binding protein (TAXREB107) that binds specifically to domain C of the tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I.
  Morita T, Sato T, Nyunoya H, Tsujimoto A, Takahara J, Irino S, Shimotohno K
  AIDS Res Hum Retroviruses. 1993
  PubMed ID: 8457378
   
  
• Location of the sulfhydryl groups involved in disulfide interaction between the neighboring proteins L6 and L29 in mammalian ribosomes. S-cleavage of the cyanylated proteins in polyacrylamide gels after separation by dodecylsulfate gel electrophoresis.
  Nika H, Hultin T
  Eur J Biochem. 1984
  PubMed ID: 6468376
   
  
• Characterization of the binding of rat liver ribosomal proteins L6, L8, L19, S9, and S13 to 5.8 S ribosomal ribonucleic acid.
  Todokoro K, Ulbrich N, Chan YL, Wool IG
  J Biol Chem. 1981
  PubMed ID: 7251593
   
  

Relevant resources:

Comment on this Page
Privacy Statement  |   Copyright, Warranty & Disclaimer  |   Contact Us
Copyright © 2001-2011, T1DBase | Version 4.8 | PMID:20937630
Printed on Fri February 10, 2012