ACTA1

Summary Top Help

Gene Description:

actin, alpha 1, skeletal muscle

Synonyms:

NEM2, MPFD, ASMA, NEM1, Acts, AA959943, CFTDM, Acta1, ACTA, CFTD, CFTD1, NEM3, Acta-2, Actsk-1, ACTA1

Orthologs:

Human ACTA1 (protein-coding), Mouse Acta1 (protein-coding), Rat Acta1 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr1:229566992..229569845 (2.85 kb) View in Genome Browser

(Mouse) NCBIM37 - chr8:126415667..126418651 (2.98 kb) View in Genome Browser

(Rat) RGSC3.4 - chr19:54081496..54084508 (31 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for ACTA1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for ACTA1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: 15

Reactome: 2

NCI-Nature Pathway Interaction Database: 4

Gene Ontology: 23

Publications from PubMed Top Help

Publications: 362

Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
Yang W, Thompson JW, Wang Z, Wang L, Sheng H, Foster MW, Moseley MA, Paschen W
J Proteome Res. 2012
PubMed ID: 22082260
Important but differential roles for actin in trafficking of Epstein-Barr virus in B cells and epithelial cells.
Valencia SM, Hutt-Fletcher LM
J Virol. 2012
PubMed ID: 22031939
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR
J Biol Chem. 2011
PubMed ID: 21987572
The first identification of lysine malonylation substrates and its regulatory enzyme.
Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y
Mol Cell Proteomics. 2011
PubMed ID: 21908771
The filopodium: a stable structure with highly regulated repetitive cycles of elongation and persistence depending on the actin cross-linker fascin.
Schäfer C, Faust U, Kirchgessner N, Merkel R, Hoffmann B
Cell Adh Migr. 2011
PubMed ID: 21975552
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse.
Rak GD, Mace EM, Banerjee PP, Svitkina T, Orange JS
PLoS Biol. 2011
PubMed ID: 21931536
Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.
Dupuis LE, McCulloch DR, McGarity JD, Bahan A, Wessels A, Weber D, Diminich AM, Nelson CM, Apte SS, Kern CB
Dev Biol. 2011
PubMed ID: 21749862
Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism.
Lin AY, Prochniewicz E, James ZM, Svensson B, Thomas DD
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21768337
Cofilin-linked changes in actin filament flexibility promote severing.
McCullough BR, Grintsevich EE, Chen CK, Kang H, Hutchison AL, Henn A, Cao W, Suarez C, Martiel JL, Blanchoin L, Reisler E, De La Cruz EM
Biophys J. 2011
PubMed ID: 21723825
Extramuscular manifestations in children with severe congenital myopathy due to ACTA1 gene mutations.
Saito Y, Komaki H, Hattori A, Takeuchi F, Sasaki M, Kawabata K, Mitsuhashi S, Tominaga K, Hayashi YK, Nowak KJ, Laing NG, Nonaka I, Nishino I
Neuromuscul Disord. 2011
PubMed ID: 21514153
CTNNBL1 Is a Novel Nuclear Localization Sequence-binding Protein That Recognizes RNA-splicing Factors CDC5L and Prp31.
Ganesh K, Adam S, Taylor B, Simpson P, Rada C, Neuberger M
J Biol Chem. 2011
PubMed ID: 21385873
Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice.
Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y
J Vet Med Sci. 2011
PubMed ID: 21186337
Modulation of chromatin position and gene expression by HDAC4 interaction with nucleoporins.
Kehat I, Accornero F, Aronow BJ, Molkentin JD
J Cell Biol. 2011
PubMed ID: 21464227
DOT1L regulates dystrophin expression and is critical for cardiac function.
Nguyen AT, Xiao B, Neppl RL, Kallin EM, Li J, Chen T, Wang DZ, Xiao X, Zhang Y
Genes Dev. 2011
PubMed ID: 21289070
Actin and Arp2/3 localize at the centrosome of interphase cells.
Hubert T, Vandekerckhove J, Gettemans J
Biochem Biophys Res Commun. 2011
PubMed ID: 21108927
Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.
An CI, Dong Y, Hagiwara N
BMC Dev Biol. 2011
PubMed ID: 21985497
The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development.
Poulsen RR, McClaskey CM, Rivkees SA, Wendler CC
BMC Dev Biol. 2011
PubMed ID: 21668976
Rapid cytoskeletal response of epithelial cells to force generation by type IV pili.
Opitz D, Maier B
PLoS One. 2011
PubMed ID: 21340023
BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization.
Ke H, Zhang JY, Akiyama SK, French JE
Cell Adh Migr. 2011
PubMed ID: 20716950
Vasodilator-stimulated phosphoprotein (VASP) induces actin assembly in dendritic spines to promote their development and potentiate synaptic strength.
Lin WH, Nebhan CA, Anderson BR, Webb DJ
J Biol Chem. 2010
PubMed ID: 20826790
Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5.
Hawkins PG, Morris KV
Transcription. 2010
PubMed ID: 21151833
PI3K-dependent host cell actin rearrangements are required for Cronobacter sakazakii invasion of human brain microvascular endothelial cells.
Li Q, Zhao WD, Zhang K, Fang WG, Hu Y, Wu SH, Chen YH
Med Microbiol Immunol. 2010
PubMed ID: 20809254
Tubulin binding protein, CacyBP/SIP, induces actin polymerization and may link actin and tubulin cytoskeletons.
Schneider G, Nieznanski K, Jozwiak J, Slomnicki LP, Redowicz MJ, Filipek A
Biochim Biophys Acta. 2010
PubMed ID: 20637809
ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing.
Bender M, Eckly A, Hartwig JH, Elvers M, Pleines I, Gupta S, Krohne G, Jeanclos E, Gohla A, Gurniak C, Gachet C, Witke W, Nieswandt B
Blood. 2010
PubMed ID: 20530287
Specific cleavage of the DNase-I binding loop dramatically decreases the thermal stability of actin.
Pivovarova AV, Khaitlina SY, Levitsky DI
FEBS J. 2010
PubMed ID: 20718862
Regulation of podocyte BK(Ca) channels by synaptopodin, Rho, and actin microfilaments.
Kim EY, Suh JM, Chiu YH, Dryer SE
Am J Physiol Renal Physiol. 2010
PubMed ID: 20630939
SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene.
Nakaoka Y, Shioyama W, Kunimoto S, Arita Y, Higuchi K, Yamamoto K, Fujio Y, Nishida K, Kuroda T, Hirota H, Yamauchi-Takihara K, Hirano T, Komuro I, Mochizuki N
J Mol Cell Cardiol. 2010
PubMed ID: 20226789
Quantitative evaluation of tryptophan oxidation in actin and troponin I from skeletal muscles using a rat model of acute oxidative stress.
Fedorova M, Todorovsky T, Kuleva N, Hoffmann R
Proteomics. 2010
PubMed ID: 20455213
The Nance-Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology.
Brooks SP, Coccia M, Tang HR, Kanuga N, Machesky LM, Bailly M, Cheetham ME, Hardcastle AJ
Hum Mol Genet. 2010
PubMed ID: 20332100
Drosophila indirect flight muscle specific Act88F actin mutants as a model system for studying congenital myopathies of the human ACTA1 skeletal muscle actin gene.
Haigh SE, Salvi SS, Sevdali M, Stark M, Goulding D, Clayton JD, Bullard B, Sparrow JC, Nongthomba U
Neuromuscul Disord. 2010
PubMed ID: 20452215
Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer's disease in the northern Han-Chinese population?
Yu G, Jia J
J Clin Neurosci. 2010
PubMed ID: 20378355
Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.
Kern CB, Wessels A, McGarity J, Dixon LJ, Alston E, Argraves WS, Geeting D, Nelson CM, Menick DR, Apte SS
Matrix Biol. 2010
PubMed ID: 20096780
TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.
Tsika RW, Ma L, Kehat I, Schramm C, Simmer G, Morgan B, Fine DM, Hanft LM, McDonald KS, Molkentin JD, Krenz M, Yang S, Ji J
J Biol Chem. 2010
PubMed ID: 20194497
Regulation of cellular actin architecture by S100A10.
Jung MJ, Murzik U, Wehder L, Hemmerich P, Melle C
Exp Cell Res. 2010
PubMed ID: 20100475
Congenital myotonic dystrophy can show congenital fiber type disproportion pathology.
Tominaga K, Hayashi YK, Goto K, Minami N, Noguchi S, Nonaka I, Miki T, Nishino I
Acta Neuropathol. 2010
PubMed ID: 20179953
Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.
Li P, Pashmforoush M, Sucov HM
Dev Cell. 2010
PubMed ID: 20230754
Human Variation in Alcohol Response Is Influenced by Variation in Neuronal Signaling Genes.
Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL
Alcohol Clin Exp Res. 2010
PubMed ID: 20201926
Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus.
Valiya Veettil M, Sadagopan S, Kerur N, Chakraborty S, Chandran B
PLoS Pathog. 2010
PubMed ID: 21203488
Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence.
Kelley LC, Hayes KE, Ammer AG, Martin KH, Weed SA
PLoS One. 2010
PubMed ID: 21079800
Altered actin centripetal retrograde flow in physically restricted immunological synapses.
Yu CH, Wu HJ, Kaizuka Y, Vale RD, Groves JT
PLoS One. 2010
PubMed ID: 20686692
Gene-gene and gene - clinical factors interaction in acute myocardial infarction: a new detailed risk chart.
Licastro F, Chiappelli M, Porcellini E, Campo G, Buscema M, Grossi E, Garoia F, Ferrari R
Curr Pharm Des. 2010
PubMed ID: 20388088
Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.
Al Tanoury Z, Schaffner-Reckinger E, Halavatyi A, Hoffmann C, Moes M, Hadzic E, Catillon M, Yatskou M, Friederich E
PLoS One. 2010
PubMed ID: 20169155
Integrative predictive model of coronary artery calcification in atherosclerosis.
McGeachie M, Ramoni RL, Mychaleckyj JC, Furie KL, Dreyfuss JM, Liu Y, Herrington D, Guo X, Lima JA, Post W, Rotter JI, Rich S, Sale M, Ramoni MF
Circulation. 2009
PubMed ID: 19948975
The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration.
Bristow JM, Sellers MH, Majumdar D, Anderson B, Hu L, Webb DJ
J Cell Sci. 2009
PubMed ID: 19934221
The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.
Lim GE, Xu M, Sun J, Jin T, Brubaker PL
Endocrinology. 2009
PubMed ID: 19819966
Actin dynamics and Rho GTPases regulate the size and formation of parasitophorous vacuoles containing Coxiella burnetii.
Aguilera M, Salinas R, Rosales E, Carminati S, Colombo MI, Berón W
Infect Immun. 2009
PubMed ID: 19635823
Mutations and polymorphisms of the skeletal muscle alpha-actin gene (ACTA1).
Laing NG, Dye DE, Wallgren-Pettersson C, Richard G, Monnier N, Lillis S, Winder TL, Lochmüller H, Graziano C, Mitrani-Rosenbaum S, Twomey D, Sparrow JC, Beggs AH, Nowak KJ
Hum Mutat. 2009
PubMed ID: 19562689
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
Myofibril assembly visualized by imaging N-RAP, alpha-actinin, and actin in living cardiomyocytes.
Manisastry SM, Zaal KJ, Horowits R
Exp Cell Res. 2009
PubMed ID: 19233165
Context-dependent functional substitution of alpha-skeletal actin by gamma-cytoplasmic actin.
Jaeger MA, Sonnemann KJ, Fitzsimons DP, Prins KW, Ervasti JM
FASEB J. 2009
PubMed ID: 19279140
Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.
Nowak KJ, Ravenscroft G, Jackaman C, Filipovska A, Davies SM, Lim EM, Squire SE, Potter AC, Baker E, Clément S, Sewry CA, Fabian V, Crawford K, Lessard JL, Griffiths LM, Papadimitriou JM, Shen Y, Morahan G, Bakker AJ, Davies KE, Laing NG
J Cell Biol. 2009
PubMed ID: 19468071
Plasma gelsolin and circulating actin correlate with hemodialysis mortality.
Lee PS, Sampath K, Karumanchi SA, Tamez H, Bhan I, Isakova T, Gutierrez OM, Wolf M, Chang Y, Stossel TP, Thadhani R
J Am Soc Nephrol. 2009
PubMed ID: 19389844
Gene-gene interaction affects coronary artery disease risk.
Mendonça MI, Dos Reis RP, Freitas AI, Sousa AC, Pereira A, Faria P, Gomes S, Silva B, Santos N, Serrao M, Ornelas I, Freitas S, Freitas C, Araújo JJ, Brehm A, Cardoso AA
Rev Port Cardiol. 2009
PubMed ID: 19634497
Polymerization of actin does not regulate desensitization in human basophils.
MacGlashan D, Vilariño N
J Leukoc Biol. 2009
PubMed ID: 19150851
Expression of CD34, alpha-smooth muscle actin and transforming growth factor-beta1 in squamous intraepithelial lesions and squamous cell carcinoma of the cervix.
Li Q, Huang W, Zhou X
J Int Med Res. 2009
PubMed ID: 19383239
Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice.
Liu X, Ramjiganesh T, Chen YH, Chung SW, Hall SR, Schissel SL, Padera RF, Liao R, Ackerman KG, Kajstura J, Leri A, Anversa P, Yet SF, Layne MD, Perrella MA
Circulation. 2009
PubMed ID: 19118250
Dependence of myoblast fusion on a cortical actin wall and nonmuscle myosin IIA.
Duan R, Gallagher PJ
Dev Biol. 2009
PubMed ID: 19027000
F- and G-actin concentrations in lamellipodia of moving cells.
Koestler SA, Rottner K, Lai F, Block J, Vinzenz M, Small JV
PLoS One. 2009
PubMed ID: 19277198
Genotype-phenotype correlations in ACTA1 mutations that cause congenital myopathies.
Feng JJ, Marston S
Neuromuscul Disord. 2009
PubMed ID: 18976909
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
Serum response factor is required for sprouting angiogenesis and vascular integrity.
Franco CA, Mericskay M, Parlakian A, Gary-Bobo G, Gao-Li J, Paulin D, Gustafsson E, Li Z
Dev Cell. 2008
PubMed ID: 18804439
Fibulin-1 is required for morphogenesis of neural crest-derived structures.
Cooley MA, Kern CB, Fresco VM, Wessels A, Thompson RP, McQuinn TC, Twal WO, Mjaatvedt CH, Drake CJ, Argraves WS
Dev Biol. 2008
PubMed ID: 18538758
Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.
Zhao R, Watt AJ, Battle MA, Li J, Bondow BJ, Duncan SA
Dev Biol. 2008
PubMed ID: 18400219
Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice.
Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18448675
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.
Yin Z, Jones GN, Towns WH, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS
Circulation. 2008
PubMed ID: 18316483
Cell-specific activation of the human skeletal alpha-actin by androgens.
Hong MH, Sun H, Jin CH, Chapman M, Hu J, Chang W, Burnett K, Rosen J, Negro-Vilar A, Miner JN
Endocrinology. 2008
PubMed ID: 18063690
Plasma gelsolin depletion and circulating actin in sepsis: a pilot study.
Lee PS, Patel SR, Christiani DC, Bajwa E, Stossel TP, Waxman AB
PLoS ONE. 2008
PubMed ID: 19002257
Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
Ballif BA, Carey GR, Sunyaev SR, Gygi SP
J Proteome Res. 2008
PubMed ID: 18034455
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
Cell. 2007
PubMed ID: 18083107
Nemaline myopathy with exclusively intranuclear rods and a novel mutation in ACTA1 (Q139H).
Koy A, Ilkovski B, Laing N, North K, Weis J, Neuen-Jacob E, Mayatepek E, Voit T
Neuropediatrics. 2007
PubMed ID: 18461503
Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c.
Potthoff MJ, Arnold MA, McAnally J, Richardson JA, Bassel-Duby R, Olson EN
Mol Cell Biol. 2007
PubMed ID: 17875930
Intranuclear rod myopathy: molecular pathogenesis and mechanisms of weakness.
Domazetovska A, Ilkovski B, Kumar V, Valova VA, Vandebrouck A, Hutchinson DO, Robinson PJ, Cooper ST, Sparrow JC, Peckham M, North KN
Ann Neurol. 2007
PubMed ID: 17705262
Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
Cao L, Yu K, Banh C, Nguyen V, Ritz A, Raphael BJ, Kawakami Y, Kawakami T, Salomon AR
J Immunol. 2007
PubMed ID: 17947660
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.
Gustafson-Wagner EA, Sinn HW, Chen YL, Wang DZ, Reiter RS, Lin JL, Yang B, Williamson RA, Chen J, Lin CI, Lin JJ
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17766470
RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.
Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J
Genes Cells. 2007
PubMed ID: 17573780
The pathogenesis of ACTA1-related congenital fiber type disproportion.
Clarke NF, Ilkovski B, Cooper S, Valova VA, Robinson PJ, Nonaka I, Feng JJ, Marston S, North K
Ann Neurol. 2007
PubMed ID: 17387733
Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function.
Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17468400
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA
Nat Med. 2007
PubMed ID: 17322895
Differential gene expression in skeletal muscle cells after membrane depolarization.
Juretić N, Urzúa U, Munroe DJ, Jaimovich E, Riveros N
J Cell Physiol. 2007
PubMed ID: 17146758
Actin filament severing by cofilin.
Pavlov D, Muhlrad A, Cooper J, Wear M, Reisler E
J Mol Biol. 2007
PubMed ID: 17134718
Phenotypes of myopathy-related actin mutants in differentiated C2C12 myotubes.
Bathe FS, Rommelaere H, Machesky LM
BMC Cell Biol. 2007
PubMed ID: 17227580
CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility.
Zhang M, Liu J, Cheng A, Deyoung SM, Chen X, Dold LH, Saltiel AR
EMBO J. 2006
PubMed ID: 17082770
Identification of plant cytoskeleton-interacting proteins by screening for actin stress fiber association in mammalian fibroblasts.
Abu-Abied M, Golomb L, Belausov E, Huang S, Geiger B, Kam Z, Staiger CJ, Sadot E
Plant J. 2006
PubMed ID: 17010111
Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation.
D'Amico A, Graziano C, Pacileo G, Petrini S, Nowak KJ, Boldrini R, Jacques A, Feng JJ, Porfirio B, Sewry CA, Santorelli FM, Limongelli G, Bertini E, Laing N, Marston SB
Neuromuscul Disord. 2006
PubMed ID: 16945537
Severe nemaline myopathy caused by mutations of the stop codon of the skeletal muscle alpha actin gene (ACTA1).
Wallefeld W, Krause S, Nowak KJ, Dye D, Horváth R, Molnár Z, Szabó M, Hashimoto K, Reina C, De Carlos J, Rosell J, Cabello A, Navarro C, Nishino I, Lochmüller H, Laing NG
Neuromuscul Disord. 2006
PubMed ID: 16945536
Apoptosis in the developing mouse heart.
Barbosky L, Lawrence DK, Karunamuni G, Wikenheiser JC, Doughman YQ, Visconti RP, Burch JB, Watanabe M
Dev Dyn. 2006
PubMed ID: 16881058
Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt.
Foster KS, McCrary WJ, Ross JS, Wright CF
Oncogene. 2006
PubMed ID: 16568092
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y
Mol Cell. 2006
PubMed ID: 16916647
A germline-specific class of small RNAs binds mammalian Piwi proteins.
Girard A, Sachidanandam R, Hannon GJ, Carmell MA
Nature. 2006
PubMed ID: 16751776
Differential gene expression in the developing mouse ureter.
Mitchell EK, Taylor DF, Woods K, Davis MJ, Nelson AL, Teasdale RD, Grimmond SM, Little MH, Bertram JF, Caruana G
Gene Expr Patterns. 2006
PubMed ID: 16459152
The DNA sequence and biological annotation of human chromosome 1.
Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E
Nature. 2006
PubMed ID: 16710414
Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.
Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ
Invest Ophthalmol Vis Sci. 2006
PubMed ID: 16638982
Correlation of alpha-skeletal actin expression, ventricular fibrosis and heart function with the degree of pressure overload cardiac hypertrophy in rats.
Stilli D, Bocchi L, Berni R, Zaniboni M, Cacciani F, Chaponnier C, Musso E, Gabbiani G, Clément S
Exp Physiol. 2006
PubMed ID: 16452123
Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.
Coiras M, Camafeita E, Ureña T, López JA, Caballero F, Fernández B, López-Huertas MR, Pérez-Olmeda M, Alcamí J
Proteomics. 2006
PubMed ID: 16526095
The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.
Bosch-Comas A, Lindsten K, Gonzàlez-Duarte R, Masucci MG, Marfany G
Cell Mol Life Sci. 2006
PubMed ID: 16501887
Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.
Ohkawa Y, Marfella CG, Imbalzano AN
EMBO J. 2006
PubMed ID: 16424906
Autosomal dominant nemaline myopathy with intranuclear rods due to mutation of the skeletal muscle ACTA1 gene: clinical and pathological variability within a kindred.
Hutchinson DO, Charlton A, Laing NG, Ilkovski B, North KN
Neuromuscul Disord. 2006
PubMed ID: 16427282
Upregulation of adrenomedullin and its receptor components during cardiomyocyte hypertrophy induced by chronic inhibition of nitric oxide synthesis in rats.
Bell D, Zhao YY, Kelso EJ, McHenry EM, Rush LM, Lamont VM, Nicholls DP, McDermott BJ
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16040721
A proteomic assessment of muscle contractile alterations during unloading and reloading.
Seo Y, Lee K, Park K, Bae K, Choi I
J Biochem. 2006
PubMed ID: 16428321
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.
Peng X, Kraus MS, Wei H, Shen TL, Pariaut R, Alcaraz A, Ji G, Cheng L, Yang Q, Kotlikoff MI, Chen J, Chien K, Gu H, Guan JL
J Clin Invest. 2006
PubMed ID: 16374517
RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Lee MJ, Tasaki T, Moroi K, An JY, Kimura S, Davydov IV, Kwon YT
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16217033
Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H.
Hagiwara N, Ma B, Ly A
Dev Dyn. 2005
PubMed ID: 16124007
Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.
Jung SY, Malovannaya A, Wei J, O'Malley BW, Qin J
Mol Endocrinol. 2005
PubMed ID: 16051665
Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.
Niu Z, Yu W, Zhang SX, Barron M, Belaguli NS, Schneider MD, Parmacek M, Nordheim A, Schwartz RJ
J Biol Chem. 2005
PubMed ID: 15929941
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.
Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V
FASEB J. 2005
PubMed ID: 15772115
Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage.
Mailleux AA, Kelly R, Veltmaat JM, De Langhe SP, Zaffran S, Thiery JP, Bellusci S
Development. 2005
PubMed ID: 15800000
GATA6 is essential for embryonic development of the liver but dispensable for early heart formation.
Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey EE, Duncan SA
Mol Cell Biol. 2005
PubMed ID: 15767668
Differential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) protein.
Lin J, Liu J, Wang Y, Zhu J, Zhou K, Smith N, Zhan X
Oncogene. 2005
PubMed ID: 15688017
Epigenetic ontogeny of the Igk locus during B cell development.
Goldmit M, Ji Y, Skok J, Roldan E, Jung S, Cedar H, Bergman Y
Nat Immunol. 2005
PubMed ID: 15619624
Eps8 controls actin-based motility by capping the barbed ends of actin filaments.
Disanza A, Carlier MF, Stradal TE, Didry D, Frittoli E, Confalonieri S, Croce A, Wehland J, Di Fiore PP, Scita G
Nat Cell Biol. 2004
PubMed ID: 15558031
Mouse myotomes pairs exhibit left-right asymmetric expression of MLC3F and alpha-skeletal actin.
Golding JP, Partridge TA, Beauchamp JR, King T, Brown NA, Gassmann M, Zammit PS
Dev Dyn. 2004
PubMed ID: 15499557
Differential actin binding along the PEVK domain of skeletal muscle titin.
Nagy A, Cacciafesta P, Grama L, Kengyel A, Málnási-Csizmadia A, Kellermayer MS
J Cell Sci. 2004
PubMed ID: 15507486
Missense mutations of ACTA1 cause dominant congenital myopathy with cores.
Kaindl AM, Rüschendorf F, Krause S, Goebel HH, Koehler K, Becker C, Pongratz D, Müller-Höcker J, Nürnberg P, Stoltenburg-Didinger G, Lochmüller H, Huebner A
J Med Genet. 2004
PubMed ID: 15520409
Actin mutations are one cause of congenital fibre type disproportion.
Laing NG, Clarke NF, Dye DE, Liyanage K, Walker KR, Kobayashi Y, Shimakawa S, Hagiwara T, Ouvrier R, Sparrow JC, Nishino I, North KN, Nonaka I
Ann Neurol. 2004
PubMed ID: 15468086
Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor.
Goley ED, Rodenbusch SE, Martin AC, Welch MD
Mol Cell. 2004
PubMed ID: 15494313
Xin repeats define a novel actin-binding motif.
Pacholsky D, Vakeel P, Himmel M, Löwe T, Stradal T, Rottner K, Fürst DO, van der Ven PF
J Cell Sci. 2004
PubMed ID: 15454575
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues.
Brozinick JT, Hawkins ED, Strawbridge AB, Elmendorf JS
J Biol Chem. 2004
PubMed ID: 15247264
Follow-up of nemaline myopathy in two patients with novel mutations in the skeletal muscle alpha-actin gene (ACTA1).
Ohlsson M, Tajsharghi H, Darin N, Kyllerman M, Oldfors A
Neuromuscul Disord. 2004
PubMed ID: 15336687
Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms.
Ilkovski B, Nowak KJ, Domazetovska A, Maxwell AL, Clement S, Davies KE, Laing NG, North KN, Cooper ST
Hum Mol Genet. 2004
PubMed ID: 15198992
Heterogeneity of nemaline myopathy cases with skeletal muscle alpha-actin gene mutations.
Agrawal PB, Strickland CD, Midgett C, Morales A, Newburger DE, Poulos MA, Tomczak KK, Ryan MM, Iannaccone ST, Crawford TO, Laing NG, Beggs AH
Ann Neurol. 2004
PubMed ID: 15236405
Myopathy mutations in alpha-skeletal-muscle actin cause a range of molecular defects.
Costa CF, Rommelaere H, Waterschoot D, Sethi KK, Nowak KJ, Laing NG, Ampe C, Machesky LM
J Cell Sci. 2004
PubMed ID: 15226407
Role of the p70(S6K) pathway in regulating the actin cytoskeleton and cell migration.
Berven LA, Willard FS, Crouch MF
Exp Cell Res. 2004
PubMed ID: 15149849
Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death.
Huang F, Wagner M, Siddiqui MA
Mech Dev. 2004
PubMed ID: 15172687
Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2-a and actin association.
Passeron T, Bahadoran P, Bertolotto C, Chiaverini C, Buscà R, Valony G, Bille K, Ortonne JP, Ballotti R
FASEB J. 2004
PubMed ID: 15059972
Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.
Lanzetti L, Palamidessi A, Areces L, Scita G, Di Fiore PP
Nature. 2004
PubMed ID: 15152255
Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.
Allen PB, Greenfield AT, Svenningsson P, Haspeslagh DC, Greengard P
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15107502
Insulin-like growth factor-induced transcriptional activity of the skeletal alpha-actin gene is regulated by signaling mechanisms linked to voltage-gated calcium channels during myoblast differentiation.
Spangenburg EE, Bowles DK, Booth FW
Endocrinology. 2004
PubMed ID: 14684598
Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy.
Tsybouleva N, Zhang L, Chen S, Patel R, Lutucuta S, Nemoto S, DeFreitas G, Entman M, Carabello BA, Roberts R, Marian AJ
Circulation. 2004
PubMed ID: 14993121
TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.
Xu J, Lai YJ, Lin WC, Lin FT
J Biol Chem. 2004
PubMed ID: 14688263
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.
Doyon Y, Selleck W, Lane WS, Tan S, Côté J
Mol Cell Biol. 2004
PubMed ID: 14966270
Novel kelch-like protein, KLEIP, is involved in actin assembly at cell-cell contact sites of Madin-Darby canine kidney cells.
Hara T, Ishida H, Raziuddin R, Dorkhom S, Kamijo K, Miki T
Mol Biol Cell. 2004
PubMed ID: 14668487
MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes.
Trinczek B, Brajenovic M, Ebneth A, Drewes G
J Biol Chem. 2004
PubMed ID: 14594945
Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding.
Simons CT, Staes A, Rommelaere H, Ampe C, Lewis SA, Cowan NJ
J Biol Chem. 2004
PubMed ID: 14634002
Actin-related myopathy without any missense mutation in the ACTA1 gene.
Goebel HH, Brockmann K, Bönnemann CG, Warlo IA, Hanefeld F, Labeit S, Durling HJ, Laing NG
J Child Neurol. 2004
PubMed ID: 15072110
Collagen type IV, laminin, alpha-smooth muscle actin (alphaSMA), alpha1 and alpha6 integrins expression in the liver with metastases from malignant gastrointestinal tumours.
Gulubova MV
Clin Exp Metastasis. 2004
PubMed ID: 15679046
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.
Wu RF, Gu Y, Xu YC, Mitola S, Bussolino F, Terada LS
J Virol. 2004
PubMed ID: 14694110
Mts1 regulates the assembly of nonmuscle myosin-IIA.
Li ZH, Spektor A, Varlamova O, Bresnick AR
Biochemistry. 2003
PubMed ID: 14640694
Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.
Salazar MA, Kwiatkowski AV, Pellegrini L, Cestra G, Butler MH, Rossman KL, Serna DM, Sondek J, Gertler FB, De Camilli P
J Biol Chem. 2003
PubMed ID: 14506234
Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction.
Yamashita H, Sugiura S, Fujita H, Yasuda S, Nagai R, Saeki Y, Sunagawa K, Sugi H
Cardiovasc Res. 2003
PubMed ID: 14659803
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function.
Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K
EMBO J. 2003
PubMed ID: 14633990
Fhos, a mammalian formin, directly binds to F-actin via a region N-terminal to the FH1 domain and forms a homotypic complex via the FH2 domain to promote actin fiber formation.
Takeya R, Sumimoto H
J Cell Sci. 2003
PubMed ID: 14576350
Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes.
Stüven T, Hartmann E, Görlich D
EMBO J. 2003
PubMed ID: 14592989
Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.
Takeuchi T, Heng HH, Ye CJ, Liang SB, Iwata J, Sonobe H, Ohtsuki Y
Am J Pathol. 2003
PubMed ID: 14507647
Muscle disease caused by mutations in the skeletal muscle alpha-actin gene (ACTA1).
Sparrow JC, Nowak KJ, Durling HJ, Beggs AH, Wallgren-Pettersson C, Romero N, Nonaka I, Laing NG
Neuromuscul Disord. 2003
PubMed ID: 12921789
CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions.
Wong AW, Brickey WJ, Taxman DJ, van Deventer HW, Reed W, Gao JX, Zheng P, Liu Y, Li P, Blum JS, McKinnon KP, Ting JP
Nat Immunol. 2003
PubMed ID: 12910265
Myogenic signaling by lithium in cardiomyoblasts is Akt independent but requires activation of the beta-catenin-Tcf/Lef pathway.
Kashour T, Burton T, Dibrov A, Amara F
J Mol Cell Cardiol. 2003
PubMed ID: 12878481
Production of human skeletal alpha-actin proteins by the baculovirus expression system.
Anthony Akkari P, Nowak KJ, Beckman K, Walker KR, Schachat F, Laing NG
Biochem Biophys Res Commun. 2003
PubMed ID: 12849983
Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1.
Eckley DM, Schroer TA
Mol Biol Cell. 2003
PubMed ID: 12857853
GATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic program.
Pikkarainen S, Tokola H, Majalahti-Palviainen T, Kerkela R, Hautala N, Bhalla SS, Charron F, Nemer M, Vuolteenaho O, Ruskoaho H
J Biol Chem. 2003
PubMed ID: 12704188
AIF-1 is an actin-polymerizing and Rac1-activating protein that promotes vascular smooth muscle cell migration.
Autieri MV, Kelemen SE, Wendt KW
Circ Res. 2003
PubMed ID: 12714565
Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146.
Butt E, Gambaryan S, Göttfert N, Galler A, Marcus K, Meyer HE
J Biol Chem. 2003
PubMed ID: 12571245
Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I.
Zhao Y, Meng XM, Wei YJ, Zhao XW, Liu DQ, Cao HQ, Liew CC, Ding JF
J Mol Med. 2003
PubMed ID: 12721663
The formin-homology-domain-containing protein FHOD1 enhances cell migration.
Koka S, Neudauer CL, Li X, Lewis RE, McCarthy JB, Westendorf JJ
J Cell Sci. 2003
PubMed ID: 12665555
Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization.
Uruno T, Zhang P, Liu J, Hao JJ, Zhan X
Biochem J. 2003
PubMed ID: 12534372
The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions.
Garvalov BK, Higgins TE, Sutherland JD, Zettl M, Scaplehorn N, Köcher T, Piddini E, Griffiths G, Way M
J Cell Biol. 2003
PubMed ID: 12695497
A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.
Blagoev B, Kratchmarova I, Ong SE, Nielsen M, Foster LJ, Mann M
Nat Biotechnol. 2003
PubMed ID: 12577067
Characterization of the motor activity of mammalian myosin VIIA.
Inoue A, Ikebe M
J Biol Chem. 2003
PubMed ID: 12466270
Actin-DBP: the perfect structural fit?
Verboven C, Bogaerts I, Waelkens E, Rabijns A, Van Baelen H, Bouillon R, De Ranter C
Acta Crystallogr D Biol Crystallogr. 2003
PubMed ID: 12554937
The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin.
Marie H, Pratt SJ, Betson M, Epple H, Kittler JT, Meek L, Moss SJ, Troyanovsky S, Attwell D, Longmore GD, Braga VM
J Biol Chem. 2003
PubMed ID: 12417594
Phosphorylation of spinophilin modulates its interaction with actin filaments.
Hsieh-Wilson LC, Benfenati F, Snyder GL, Allen PB, Nairn AC, Greengard P
J Biol Chem. 2003
PubMed ID: 12417592
Association of phospholamban with a cGMP kinase signaling complex.
Koller A, Schlossmann J, Ashman K, Uttenweiler-Joseph S, Ruth P, Hofmann F
Biochem Biophys Res Commun. 2003
PubMed ID: 12480535
Regulation of phospholipase D activity by actin. Actin exerts bidirectional modulation of Mammalian phospholipase D activity in a polymerization-dependent, isoform-specific manner.
Kusner DJ, Barton JA, Wen KK, Wang X, Rubenstein PA, Iyer SS
J Biol Chem. 2002
PubMed ID: 12388543
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Characterization of human alpha-dystrobrevin isoforms in HL-60 human promyelocytic leukemia cells undergoing granulocytic differentiation.
Kulyte A, Navakauskiene R, Treigyte G, Gineitis A, Bergman T, Magnusson KE
Mol Biol Cell. 2002
PubMed ID: 12475945
Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.
Taddei ML, Chiarugi P, Cirri P, Buricchi F, Fiaschi T, Giannoni E, Talini D, Cozzi G, Formigli L, Raugei G, Ramponi G
Cancer Res. 2002
PubMed ID: 12438242
The DIX domain targets dishevelled to actin stress fibres and vesicular membranes.
Capelluto DG, Kutateladze TG, Habas R, Finkielstein CV, He X, Overduin M
Nature. 2002
PubMed ID: 12384700
The role of different Scinderin domains in the control of F-actin cytoskeleton during exocytosis.
Lejen T, Pene TD, Rosé SD, Trifaró JM
Ann N Y Acad Sci. 2002
PubMed ID: 12438125
The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin.
Patchell VB, Gallon CE, Hodgkin MA, Fattoum A, Perry SV, Levine BA
Eur J Biochem. 2002
PubMed ID: 12383268
Eps8 in the midst of GTPases.
Di Fiore PP, Scita G
Int J Biochem Cell Biol. 2002
PubMed ID: 12127568
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.
Shin CH, Liu ZP, Passier R, Zhang CL, Wang DZ, Harris TM, Yamagishi H, Richardson JA, Childs G, Olson EN
Cell. 2002
PubMed ID: 12297046
Expression and biological activity of Baculovirus generated wild-type human slow alpha tropomyosin and the Met9Arg mutant responsible for a dominant form of nemaline myopathy.
Akkari PA, Song Y, Hitchcock-DeGregori S, Blechynden L, Laing N
Biochem Biophys Res Commun. 2002
PubMed ID: 12163017
Mice lacking skeletal muscle actin show reduced muscle strength and growth deficits and die during the neonatal period.
Crawford K, Flick R, Close L, Shelly D, Paul R, Bove K, Kumar A, Lessard J
Mol Cell Biol. 2002
PubMed ID: 12138199
Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.
Head JF, Swamy N, Ray R
Biochemistry. 2002
PubMed ID: 12119014
ACT and UCH-L1 polymorphisms in Parkinson's disease and age of onset.
Wang J, Zhao CY, Si YM, Liu ZL, Chen B, Yu L
Mov Disord. 2002
PubMed ID: 12210873
Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system.
Otterbein LR, Cosio C, Graceffa P, Dominguez R
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12048248
Functional characterization of spectrin-actin-binding domains in 4.1 family of proteins.
Gimm JA, An X, Nunomura W, Mohandas N
Biochemistry. 2002
PubMed ID: 12044158
PKC epsilon is associated with myosin IIA and actin in fibroblasts.
England K, Ashford D, Kidd D, Rumsby M
Cell Signal. 2002
PubMed ID: 11897493
HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain.
Legendre-Guillemin V, Metzler M, Charbonneau M, Gan L, Chopra V, Philie J, Hayden MR, McPherson PS
J Biol Chem. 2002
PubMed ID: 11889126
Functional analysis of rat acidic calponin.
Fujii T, Yabe S, Nakamura K, Koizumi Y
Biol Pharm Bull. 2002
PubMed ID: 12033495
Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle.
Rybakova IN, Patel JR, Davies KE, Yurchenco PD, Ervasti JM
Mol Biol Cell. 2002
PubMed ID: 12006649
Dendrite-like process formation and cytoskeletal remodeling regulated by delta-catenin expression.
Kim K, Sirota A, Chen Yh YH, Jones SB, Dudek R, Lanford GW, Thakore C, Lu Q
Exp Cell Res. 2002
PubMed ID: 11969288
Identification of casein kinase Ialpha interacting protein partners.
Dubois T, Howell S, Zemlickova E, Aitken A
FEBS Lett. 2002
PubMed ID: 12062430
Human CAP1 is a key factor in the recycling of cofilin and actin for rapid actin turnover.
Moriyama K, Yahara I
J Cell Sci. 2002
PubMed ID: 11950878
Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy.
Koga H, Kaji Y, Nishii K, Shirai M, Tomotsune D, Osugi T, Sawada A, Kim JY, Hara J, Miwa T, Yamauchi-Takihara K, Shibata Y, Takihara Y
Lab Invest. 2002
PubMed ID: 11950896
CHO1, a mammalian kinesin-like protein, interacts with F-actin and is involved in the terminal phase of cytokinesis.
Kuriyama R, Gustus C, Terada Y, Uetake Y, Matuliene J
J Cell Biol. 2002
PubMed ID: 11877456
Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth.
Bonilla IE, Tanabe K, Strittmatter SM
J Neurosci. 2002
PubMed ID: 11850458
Solution structure of the calponin CH domain and fitting to the 3D-helical reconstruction of F-actin:calponin.
Bramham J, Hodgkinson JL, Smith BO, Uhrín D, Barlow PN, Winder SJ
Structure. 2002
PubMed ID: 11839310
Association of the growth-arrest-specific protein Gas7 with F-actin induces reorganization of microfilaments and promotes membrane outgrowth.
She BR, Liou GG, Lin-Chao S
Exp Cell Res. 2002
PubMed ID: 11795944
Polymerisation of chemically cross-linked actin:thymosin beta(4) complex to filamentous actin: alteration in helical parameters and visualisation of thymosin beta(4) binding on F-actin.
Ballweber E, Hannappel E, Huff T, Stephan H, Haener M, Taschner N, Stoffler D, Aebi U, Mannherz HG
J Mol Biol. 2002
PubMed ID: 11812134
The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage.
Okorokov AL, Rubbi CP, Metcalfe S, Milner J
Oncogene. 2002
PubMed ID: 11821948
Nuclear DNA helicase II/RNA helicase A binds to filamentous actin.
Zhang S, Buder K, Burkhardt C, Schlott B, Görlach M, Grosse F
J Biol Chem. 2002
PubMed ID: 11687588
Interaction of ADP-ribosylated actin with actin binding proteins.
Ballweber E, Galla M, Aktories K, Yeoh S, Weeds AG, Mannherz HG
FEBS Lett. 2001
PubMed ID: 11707283
Interaction between PEVK-titin and actin filaments: origin of a viscous force component in cardiac myofibrils.
Kulke M, Fujita-Becker S, Rostkova E, Neagoe C, Labeit D, Manstein DJ, Gautel M, Linke WA
Circ Res. 2001
PubMed ID: 11701614
Human APC2 localization and allelic imbalance.
Jarrett CR, Blancato J, Cao T, Bressette DS, Cepeda M, Young PE, King CR, Byers SW
Cancer Res. 2001
PubMed ID: 11691822
Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75.
Provost P, Doucet J, Stock A, Gerisch G, Samuelsson B, Rådmark O
Biochem J. 2001
PubMed ID: 11583571
Inositol 1,4,5-trisphosphate 3-kinase A associates with F-actin and dendritic spines via its N terminus.
Schell MJ, Erneux C, Irvine RF
J Biol Chem. 2001
PubMed ID: 11468283
Actin cytoskeletal association of cytohesin-1 is regulated by specific phosphorylation of its carboxyl-terminal polybasic domain.
Dierks H, Kolanus J, Kolanus W
J Biol Chem. 2001
PubMed ID: 11438522
beta III spectrin binds to the Arp1 subunit of dynactin.
Holleran EA, Ligon LA, Tokito M, Stankewich MC, Morrow JS, Holzbaur EL
J Biol Chem. 2001
PubMed ID: 11461920
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine.
Scita G, Tenca P, Areces LB, Tocchetti A, Frittoli E, Giardina G, Ponzanelli I, Sini P, Innocenti M, Di Fiore PP
J Cell Biol. 2001
PubMed ID: 11524436
Potential genetic markers of sporadic Alzheimer's dementia.
Retz W, Thome J, Durany N, Harsányi A, Retz-Junginger P, Kornhuber J, Riederer P, Rösler M
Psychiatr Genet. 2001
PubMed ID: 11702052
Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas.
VanHouten JN, Asch HL, Asch BB
Oncogene. 2001
PubMed ID: 11536049
Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction.
Hatch V, Zhi G, Smith L, Stull JT, Craig R, Lehman W
J Cell Biol. 2001
PubMed ID: 11481347
Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin.
Llorca O, Martín-Benito J, Gómez-Puertas P, Ritco-Vonsovici M, Willison KR, Carrascosa JL, Valpuesta JM
J Struct Biol. 2001
PubMed ID: 11580270
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
Woodring PJ, Hunter T, Wang JY
J Biol Chem. 2001
PubMed ID: 11309382
Cutting edge: integration of human T lymphocyte cytoskeleton by the cytolinker plectin.
Brown MJ, Hallam JA, Liu Y, Yamada KM, Shaw S
J Immunol. 2001
PubMed ID: 11441066
Protein kinase C-delta C2-like domain is a binding site for actin and enables actin redistribution in neutrophils.
López-Lluch G, Bird MM, Canas B, Godovac-Zimmerman J, Ridley A, Segal AW, Dekker LV
Biochem J. 2001
PubMed ID: 11415434
Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation.
Ikeda W, Nakanishi H, Tanaka Y, Tachibana K, Takai Y
Oncogene. 2001
PubMed ID: 11429692
Nemaline myopathy caused by mutations in the muscle alpha-skeletal-actin gene.
Ilkovski B, Cooper ST, Nowak K, Ryan MM, Yang N, Schnell C, Durling HJ, Roddick LG, Wilkinson I, Kornberg AJ, Collins KJ, Wallace G, Gunning P, Hardeman EC, Laing NG, North KN
Am J Hum Genet. 2001
PubMed ID: 11333380
5-Lipoxygenase interacts with coactosin-like protein.
Provost P, Doucet J, Hammarberg T, Gerisch G, Samuelsson B, Radmark O
J Biol Chem. 2001
PubMed ID: 11297527
Binding of dystrophin's tandem calponin homology domain to F-actin is modulated by actin's structure.
Orlova A, Rybakova IN, Prochniewicz E, Thomas DD, Ervasti JM, Egelman EH
Biophys J. 2001
PubMed ID: 11259305
Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.
Humphrey GW, Wang Y, Russanova VR, Hirai T, Qin J, Nakatani Y, Howard BH
J Biol Chem. 2001
PubMed ID: 11102443
Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.
Bruneau BG, Bao ZZ, Fatkin D, Xavier-Neto J, Georgakopoulos D, Maguire CT, Berul CI, Kass DA, Kuroski-de Bold ML, de Bold AJ, Conner DA, Rosenthal N, Cepko CL, Seidman CE, Seidman JG
Mol Cell Biol. 2001
PubMed ID: 11238910
Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells.
Gale NW, Baluk P, Pan L, Kwan M, Holash J, DeChiara TM, McDonald DM, Yancopoulos GD
Dev Biol. 2001
PubMed ID: 11161569
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily.
Olski TM, Noegel AA, Korenbaum E
J Cell Sci. 2001
PubMed ID: 11171322
Mild phenotype of nemaline myopathy with sleep hypoventilation due to a mutation in the skeletal muscle alpha-actin (ACTA1) gene.
Jungbluth H, Sewry CA, Brown SC, Nowak KJ, Laing NG, Wallgren-Pettersson C, Pelin K, Manzur AY, Mercuri E, Dubowitz V, Muntoni F
Neuromuscul Disord. 2001
PubMed ID: 11166164
Alteration of tropomyosin function and folding by a nemaline myopathy-causing mutation.
Moraczewska J, Greenfield NJ, Liu Y, Hitchcock-DeGregori SE
Biophys J. 2000
PubMed ID: 11106625
Actin-binding properties and colocalization with actin during spermiogenesis of mammalian sperm calicin.
Lécuyer C, Dacheux JL, Hermand E, Mazeman E, Rousseaux J, Rousseaux-Prévost R
Biol Reprod. 2000
PubMed ID: 11090452
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
A nonerythroid isoform of protein 4.1R interacts with components of the contractile apparatus in skeletal myofibers.
Kontrogianni-Konstantopoulos A, Huang SC, Benz EJ
Mol Biol Cell. 2000
PubMed ID: 11071908
Mutagenesis analysis of human SM22: characterization of actin binding.
Fu Y, Liu HW, Forsythe SM, Kogut P, McConville JF, Halayko AJ, Camoretti-Mercado B, Solway J
J Appl Physiol. 2000
PubMed ID: 11053353
Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin.
Harbeck B, Hüttelmaier S, Schluter K, Jockusch BM, Illenberger S
J Biol Chem. 2000
PubMed ID: 10882740
Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase.
Tamura M, Kai T, Tsunawaki S, Lambeth JD, Kameda K
Biochem Biophys Res Commun. 2000
PubMed ID: 11027608
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.
Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, Cooper JA, Parsons JT
J Cell Biol. 2000
PubMed ID: 11018051
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.
Berg JS, Derfler BH, Pennisi CM, Corey DP, Cheney RE
J Cell Sci. 2000
PubMed ID: 10984435
Myotilin is mutated in limb girdle muscular dystrophy 1A.
Hauser MA, Horrigan SK, Salmikangas P, Torian UM, Viles KD, Dancel R, Tim RW, Taivainen A, Bartoloni L, Gilchrist JM, Stajich JM, Gaskell PC, Gilbert JR, Vance JM, Pericak-Vance MA, Carpen O, Westbrook CA, Speer MC
Hum Mol Genet. 2000
PubMed ID: 10958653
SMAR1, a novel, alternatively spliced gene product, binds the Scaffold/Matrix-associated region at the T cell receptor beta locus.
Chattopadhyay S, Kaul R, Charest A, Housman D, Chen J
Genomics. 2000
PubMed ID: 10950932
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.
Lamb RF, Roy C, Diefenbach TJ, Vinters HV, Johnson MW, Jay DG, Hall A
Nat Cell Biol. 2000
PubMed ID: 10806479
Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.
Berryman M, Bretscher A
Mol Biol Cell. 2000
PubMed ID: 10793131
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent.
Kablar B, Tajbakhsh S, Rudnicki MA
Development. 2000
PubMed ID: 10725239
The mouse N-acetylgalactosamine-6-sulfate sulfatase (Galns) gene: cDNA isolation, genomic characterization, chromosomal assignment and analysis of the 5'-flanking region.
Montaño AM, Yamagishi A, Tomatsu S, Fukuda S, Copeland NG, Orii KE, Isogai K, Yamada N, Kato ZI, Jenkins NA, Gilbert DJ, Sukegawa K, Orii T, Kondo N
Biochim Biophys Acta. 2000
PubMed ID: 10699374
Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4.
Valdez MR, Richardson JA, Klein WH, Olson EN
Dev Biol. 2000
PubMed ID: 10694423
The carboxy terminus of AFAP-110 modulates direct interactions with actin filaments and regulates its ability to alter actin filament integrity and induce lamellipodia formation.
Qian Y, Baisden JM, Zot HG, Van Winkle WB, Flynn DC
Exp Cell Res. 2000
PubMed ID: 10666339
Microtubule actin cross-linking factor (MACF): a hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons.
Leung CL, Sun D, Zheng M, Knowles DR, Liem RK
J Cell Biol. 1999
PubMed ID: 10601340
Functional genomic analysis reveals the utility of the I/LWEQ module as a predictor of protein:actin interaction.
McCann RO, Craig SW
Biochem Biophys Res Commun. 1999
PubMed ID: 10581178
Domain movement in gelsolin: a calcium-activated switch.
Robinson RC, Mejillano M, Le VP, Burtnick LD, Yin HL, Choe S
Science. 1999
PubMed ID: 10583954
Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3.
Wittchen ES, Haskins J, Stevenson BR
J Biol Chem. 1999
PubMed ID: 10575001
Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis.
Sgorbissa A, Benetti R, Marzinotto S, Schneider C, Brancolini C
J Cell Sci. 1999
PubMed ID: 10564664
Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins.
Sun Y, Zhang J, Kraeft SK, Auclair D, Chang MS, Liu Y, Sutherland R, Salgia R, Griffin JD, Ferland LH, Chen LB
J Biol Chem. 1999
PubMed ID: 10559237
Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.
Zhang H, Wang L, Kao S, Whitehead IP, Hart MJ, Liu B, Duus K, Burridge K, Der CJ, Su L
Curr Biol. 1999
PubMed ID: 10556093
Mutations in the skeletal muscle alpha-actin gene in patients with actin myopathy and nemaline myopathy.
Nowak KJ, Wattanasirichaigoon D, Goebel HH, Wilce M, Pelin K, Donner K, Jacob RL, Hübner C, Oexle K, Anderson JR, Verity CM, North KN, Iannaccone ST, Müller CR, Nürnberg P, Muntoni F, Sewry C, Hughes I, Sutphen R, Lacson AG, Swoboda KJ, Vigneron J, Wallgren-Pettersson C, Beggs AH, Laing NG
Nat Genet. 1999
PubMed ID: 10508519
Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis.
McCartney BM, Dierick HA, Kirkpatrick C, Moline MM, Baas A, Peifer M, Bejsovec A
J Cell Biol. 1999
PubMed ID: 10491393
Interaction between protein kinase C and actin in megakaryocyte polyploidization.
Baatout S, Chatelain B, Staquet P, Symann M, Chatelain C
Anticancer Res. 1999
PubMed ID: 10628374
The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formation.
Bachmann C, Fischer L, Walter U, Reinhard M
J Biol Chem. 1999
PubMed ID: 10438535
Aip1p interacts with cofilin to disassemble actin filaments.
Rodal AA, Tetreault JW, Lappalainen P, Drubin DG, Amberg DC
J Cell Biol. 1999
PubMed ID: 10366597
Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.
Luo G, Herrera AH, Horowits R
Biochemistry. 1999
PubMed ID: 10320340
A neurally enriched coronin-like protein, ClipinC, is a novel candidate for an actin cytoskeleton-cortical membrane-linking protein.
Nakamura T, Takeuchi K, Muraoka S, Takezoe H, Takahashi N, Mori N
J Biol Chem. 1999
PubMed ID: 10224093
Cytosine methylation and mammalian development.
Walsh CP, Bestor TH
Genes Dev. 1999
PubMed ID: 9887097
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation.
Buss F, Kendrick-Jones J, Lionne C, Knight AE, Côté GP, Paul Luzio J
J Cell Biol. 1998
PubMed ID: 9852149
Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.
Bukrinskaya A, Brichacek B, Mann A, Stevenson M
J Exp Med. 1998
PubMed ID: 9841925
Nexilin: a novel actin filament-binding protein localized at cell-matrix adherens junction.
Ohtsuka T, Nakanishi H, Ikeda W, Satoh A, Momose Y, Nishioka H, Takai Y
J Cell Biol. 1998
PubMed ID: 9832551
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton.
Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM
J Biol Chem. 1998
PubMed ID: 9792688
Serum response factor is essential for mesoderm formation during mouse embryogenesis.
Arsenian S, Weinhold B, Oelgeschläger M, Rüther U, Nordheim A
EMBO J. 1998
PubMed ID: 9799237
A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I.
Jha PK, Sarkar S
Biochemistry. 1998
PubMed ID: 9724539
Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calcium.
Mandinova A, Atar D, Schäfer BW, Spiess M, Aebi U, Heizmann CW
J Cell Sci. 1998
PubMed ID: 9645951
Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase.
Obaishi H, Nakanishi H, Mandai K, Satoh K, Satoh A, Takahashi K, Miyahara M, Nishioka H, Takaishi K, Takai Y
J Biol Chem. 1998
PubMed ID: 9668039
Haemopoietic transformation by the TEL/ABL oncogene.
Hannemann JR, McManus DM, Kabarowski JH, Wiedemann LM
Br J Haematol. 1998
PubMed ID: 9695962
Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice.
Rawls A, Valdez MR, Zhang W, Richardson J, Klein WH, Olson EN
Development. 1998
PubMed ID: 9609818
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.
Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG, Iliopoulos O
Mol Cell. 1998
PubMed ID: 9651579
Transcriptional regulation of muscle-specific genes during myoblast differentiation.
Shimokawa T, Kato M, Ezaki O, Hashimoto S
Biochem Biophys Res Commun. 1998
PubMed ID: 9600108
E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeleton.
Reuver SM, Garner CC
J Cell Sci. 1998
PubMed ID: 9512503
Human myosin-IXb is a mechanochemically active motor and a GAP for rho.
Post PL, Bokoch GM, Mooseker MS
J Cell Sci. 1998
PubMed ID: 9490638
p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.
Kobayashi K, Kuroda S, Fukata M, Nakamura T, Nagase T, Nomura N, Matsuura Y, Yoshida-Kubomura N, Iwamatsu A, Kaibuchi K
J Biol Chem. 1998
PubMed ID: 9417078
Assignment of the human skeletal muscle [FC12]a-actin gene (ACTA1) to chromosome 1q42.13-->q42.2 by radiation hybrid mapping.
Mogensen J, Kruse TA, Børglum AD
Cytogenet Cell Genet. 1998
PubMed ID: 10072583
Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.
Rosen ED, Chan JC, Idusogie E, Clotman F, Vlasuk G, Luther T, Jalbert LR, Albrecht S, Zhong L, Lissens A, Schoonjans L, Moons L, Collen D, Castellino FJ, Carmeliet P
Nature. 1997
PubMed ID: 9384381
Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells.
Dharmawardhane S, Sanders LC, Martin SS, Daniels RH, Bokoch GM
J Cell Biol. 1997
PubMed ID: 9298982
Actin-titin interaction in cardiac myofibrils: probing a physiological role.
Linke WA, Ivemeyer M, Labeit S, Hinssen H, Rüegg JC, Gautel M
Biophys J. 1997
PubMed ID: 9251807
Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments.
Itoh M, Nagafuchi A, Moroi S, Tsukita S
J Cell Biol. 1997
PubMed ID: 9214391
IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments.
Bashour AM, Fullerton AT, Hart MJ, Bloom GS
J Cell Biol. 1997
PubMed ID: 9199170
Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends.
Safer D, Sosnick TR, Elzinga M
Biochemistry. 1997
PubMed ID: 9153421
Localization of the mitochondrial carbonic anhydrase V gene, Car5, on mouse chromosome 8.
Lakkis MM, Venta PJ, Tashian RE
Mamm Genome. 1997
PubMed ID: 9069129
Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin.
Ono S, Yamakita Y, Yamashiro S, Matsudaira PT, Gnarra JR, Obinata T, Matsumura F
J Biol Chem. 1997
PubMed ID: 8999969
The gene encoding subunit IV of cytochrome c oxidase maps to mouse chromosome 8.
Makris GJ, Samuelson LC, Lomax MI
Mamm Genome. 1996
PubMed ID: 8854875
Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development.
Kaestner KH, Bleckmann SC, Monaghan AP, Schlöndorff J, Mincheva A, Lichter P, Schütz G
Development. 1996
PubMed ID: 8674414
The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development.
Labosky PA, Winnier GE, Sasaki H, Blessing M, Hogan BL
Genomics. 1996
PubMed ID: 8661058
Human mineralocorticoid receptor interacts with actin under mineralocorticoid ligand modulation.
Jalaguier S, Mornet D, Mesnier D, Léger JJ, Auzou G
FEBS Lett. 1996
PubMed ID: 8612804
The cleavage of host cell proteins by HIV-1 protease.
Snásel J, Pichová I
Folia Biol (Praha). 1996
PubMed ID: 8997639
Identification and localization of an actin-binding motif that is unique to the epsilon isoform of protein kinase C and participates in the regulation of synaptic function.
Prekeris R, Mayhew MW, Cooper JB, Terrian DM
J Cell Biol. 1996
PubMed ID: 8567732
Direct binding of F actin to the cytoplasmic domain of the alpha 2 integrin chain in vitro.
Kieffer JD, Plopper G, Ingber DE, Hartwig JH, Kupper TS
Biochem Biophys Res Commun. 1995
PubMed ID: 7503723
Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome.
Patapoutian A, Yoon JK, Miner JH, Wang S, Stark K, Wold B
Development. 1995
PubMed ID: 7588068
Adducin: a physical model with implications for function in assembly of spectrin-actin complexes.
Hughes CA, Bennett V
J Biol Chem. 1995
PubMed ID: 7642559
The nucleotide sequence, structure, and preliminary studies on the transcriptional regulation of the bovine alpha skeletal actin gene.
Davey HW, Kelly JK, Wildeman AG
DNA Cell Biol. 1995
PubMed ID: 7626220
Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies.
Zhang W, Behringer RR, Olson EN
Genes Dev. 1995
PubMed ID: 7797078
Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.
Robinson RC, Radziejewski C, Stuart DI, Jones EY
Biochemistry. 1995
PubMed ID: 7703225
Muscle-specific gene expression during myogenesis in the mouse.
Ontell M, Ontell MP, Buckingham M
Microsc Res Tech. 1995
PubMed ID: 7787235
Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.
Ueyama H, Inazawa J, Ariyama T, Nishino H, Ochiai Y, Ohkubo I, Miwa T
Jpn J Hum Genet. 1995
PubMed ID: 7780165
F-actin binding site masked by the intramolecular association of vinculin head and tail domains.
Johnson RP, Craig SW
Nature. 1995
PubMed ID: 7816144
Mapping the gene that encodes phosphatidylinositol-specific phospholipase C-gamma 2 in the human and the mouse.
Hernandez D, Egan SE, Yulug IG, Fisher EM
Genomics. 1994
PubMed ID: 7835906
Syntenic assignment of human chromosome 1 homologous loci in the bovine.
Threadgill DS, Threadgill DW, Moll YD, Weiss JA, Zhang N, Davey HW, Wildeman AG, Womack JE
Genomics. 1994
PubMed ID: 8001974
Modulation of alpha-actinin levels affects cell motility and confers tumorigenicity on 3T3 cells.
Glück U, Ben-Ze'ev A
J Cell Sci. 1994
PubMed ID: 7983147
Genetic mapping of 40 cDNA clones on the mouse genome by PCR.
Ko MS, Wang X, Horton JH, Hagen MD, Takahashi N, Maezaki Y, Nadeau JH
Mamm Genome. 1994
PubMed ID: 8043949
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.
Rowe LB, Nadeau JH, Turner R, Frankel WN, Letts VA, Eppig JT, Ko MS, Thurston SJ, Birkenmeier EH
Mamm Genome. 1994
PubMed ID: 8075499
Subtractive cDNA cloning as a tool to analyse secondary effects of a muscle disease. Characterization of affected genes in the myotonic ADR mouse.
Schleef M, Zühlke C, Schöffl F, Jockusch H
Neuromuscul Disord. 1994
PubMed ID: 7522680
Towards high resolution maps of the mouse and human genomes--a facility for ordering markers to 0.1 cM resolution. European Backcross Collaborative Group.

Hum Mol Genet. 1994
PubMed ID: 8069308
Assignment of the human skeletal muscle alpha actin gene (ACTA1) to 1q42 by fluorescence in situ hybridisation.
Akkari PA, Eyre HJ, Wilton SD, Callen DF, Lane SA, Meredith C, Kedes L, Laing NG
Cytogenet Cell Genet. 1994
PubMed ID: 8258301
Congenital myopathy with fiber type disproportion: a family with a chromosomal translocation t(10;17) may indicate candidate gene regions.
Gerdes AM, Petersen MB, Schrøder HD, Wulff K, Brøndum-Nielsen K
Clin Genet. 1994
PubMed ID: 7908614
Microtubule associated protein MAP1A is an actin-binding and crosslinking protein.
Pedrotti B, Colombo R, Islam K
Cell Motil Cytoskeleton. 1994
PubMed ID: 7820861
Microtubule-associated proteins, MAP 1A and MAP 1B, interact with F-actin in vitro.
Fujii T, Watanabe M, Ogoma Y, Kondo Y, Arai T
J Biochem. 1993
PubMed ID: 7908020
Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.
Ontell MP, Sopper MM, Lyons G, Buckingham M, Ontell M
Dev Dyn. 1993
PubMed ID: 8136524
The structure of crystalline profilin-beta-actin.
Schutt CE, Myslik JC, Rozycki MD, Goonesekere NC, Lindberg U
Nature. 1993
PubMed ID: 8413665
Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin.
Massia SP, Rao SS, Hubbell JA
J Biol Chem. 1993
PubMed ID: 8463322
The short 3'-end region of complementary DNAs as PCR-based polymorphic markers for an expression map of the mouse genome.
Takahashi N, Ko MS
Genomics. 1993
PubMed ID: 8486351
Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.
Ontell M, Ontell MP, Sopper MM, Mallonga R, Lyons G, Buckingham M
Development. 1993
PubMed ID: 8404542
Expression of intercellular adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3.
Seko Y, Matsuda H, Kato K, Hashimoto Y, Yagita H, Okumura K, Yazaki Y
J Clin Invest. 1993
PubMed ID: 8097205
Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.
Wu H, Parsons JT
J Cell Biol. 1993
PubMed ID: 7680654
Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins.
Yu FX, Lin SC, Morrison-Bogorad M, Atkinson MA, Yin HL
J Biol Chem. 1993
PubMed ID: 8416954
Re-localization of Actsk-1 to mouse chromosome 8, a new region of homology with human chromosome 1.
Alonso S, Montagutelli X, Simon-Chazottes D, Guénet JL, Buckingham M
Mamm Genome. 1993
PubMed ID: 8422497
Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage.
Abonia JP, Abel KJ, Eddy RL, Elliott RW, Chapman VM, Shows TB, Gross KW
Mamm Genome. 1993
PubMed ID: 8093670
Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation.
van der Ven PF, Schaart G, Jap PH, Sengers RC, Stadhouders AM, Ramaekers FC
Cell Tissue Res. 1992
PubMed ID: 1423520
The EGF receptor is an actin-binding protein.
den Hartigh JC, van Bergen en Henegouwen PM, Verkleij AJ, Boonstra J
J Cell Biol. 1992
PubMed ID: 1383230
Modulation of embryonic and muscle-specific enolase gene products in the developing mouse hindlimb.
Lucas M, Goblet C, Keller A, Lamandé N, Gros F, Whalen RG, Lazar M
Differentiation. 1992
PubMed ID: 1280607
Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic mouse heart.
Miner JH, Miller JB, Wold BJ
Development. 1992
PubMed ID: 1618148
Binding sites involved in the interaction of actin with the N-terminal region of dystrophin.
Levine BA, Moir AJ, Patchell VB, Perry SV
FEBS Lett. 1992
PubMed ID: 1544421
HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.
Adams LD, Tomasselli AG, Robbins P, Moss B, Heinrikson RL
AIDS Res Hum Retroviruses. 1992
PubMed ID: 1540415
Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.
Cox RD, Buckingham ME
Dev Biol. 1992
PubMed ID: 1728592
Epidermal growth factor induces rapid reorganization of the actin microfilament system in human A431 cells.
Rijken PJ, Hage WJ, van Bergen en Henegouwen PM, Verkleij AJ, Boonstra J
J Cell Sci. 1991
PubMed ID: 1808202
Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.
Tomasselli AG, Hui JO, Adams L, Chosay J, Lowery D, Greenberg B, Yem A, Deibel MR, Zürcher-Neely H, Heinrikson RL
J Biol Chem. 1991
PubMed ID: 1907279
Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Teeter LD, Petersen DD, Nebert DW, Kuo MT
DNA Cell Biol. 1991
PubMed ID: 2069718
alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.
Lyons GE, Buckingham ME, Mannherz HG
Development. 1991
PubMed ID: 1893870
Non-viral cellular substrates for human immunodeficiency virus type 1 protease.
Shoeman RL, Kesselmier C, Mothes E, Höner B, Traub P
FEBS Lett. 1991
PubMed ID: 1991513
Atomic structure of the actin:DNase I complex.
Kabsch W, Mannherz HG, Suck D, Pai EF, Holmes KC
Nature. 1990
PubMed ID: 2395459
Smooth muscle calponin. Inhibition of actomyosin MgATPase and regulation by phosphorylation.
Winder SJ, Walsh MP
J Biol Chem. 1990
PubMed ID: 2161834
Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line.
Cox RD, Garner I, Buckingham ME
Differentiation. 1990
PubMed ID: 2201580
A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.
Garner I, Sassoon D, Vandekerckhove J, Alonso S, Buckingham ME
Dev Biol. 1989
PubMed ID: 2731651
Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains.
Taylor A, Erba HP, Muscat GE, Kedes L
Genomics. 1988
PubMed ID: 2907503
Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.
Sassoon DA, Garner I, Buckingham M
Development. 1988
PubMed ID: 3075543
Vascular smooth muscle calponin. A novel troponin T-like protein.
Takahashi K, Hiwada K, Kokubu T
Hypertension. 1988
PubMed ID: 2455687
Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes.
Yang-Feng TL, Schneider JW, Lindgren V, Shull MM, Benz EJ, Lingrel JB, Francke U
Genomics. 1988
PubMed ID: 2842249
Mouse skeletal alpha actin has limited restriction fragment length polymorphism and is not a member of the human 1q-mouse distal chromosome 1 syntatic group.
Seldin MF, D'Hoostelaere LA, Steinberg AD
Nucleic Acids Res. 1987
PubMed ID: 2881279
Tropomyosin distinguishes between the two actin-binding sites of villin and affects actin-binding properties of other brush border proteins.
Burgess DR, Broschat KO, Hayden JM
J Cell Biol. 1987
PubMed ID: 3793760
A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.
Garner I, Minty AJ, Alonso S, Barton PJ, Buckingham ME
EMBO J. 1986
PubMed ID: 3023046
Isolation and characterization of cDNA clones from mouse skeletal muscle actin mRNA.
Leader DP, Gall I, Campbell P, Frischauf AM
DNA. 1986
PubMed ID: 3013550
Ultrastructure of the intact skeleton of the human erythrocyte membrane.
Shen BW, Josephs R, Steck TL
J Cell Biol. 1986
PubMed ID: 2936753
Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.
Alonso S, Minty A, Bourlet Y, Buckingham M
J Mol Evol. 1986
PubMed ID: 3084797
The complete sequence of the mouse skeletal alpha-actin gene reveals several conserved and inverted repeat sequences outside of the protein-coding region.
Hu MC, Sharp SB, Davidson N
Mol Cell Biol. 1986
PubMed ID: 3023820
Investigation of genetic linkage between myosin and actin genes using an interspecific mouse back-cross.
Robert B, Barton P, Minty A, Daubas P, Weydert A, Bonhomme F, Catalan J, Chazottes D, Guénet JL, Buckingham M
Nature. 1985
PubMed ID: 2983233
The human beta-actin multigene family.
Kedes L, Ng SY, Lin CS, Gunning P, Eddy R, Shows T, Leavitt J
Trans Assoc Am Physicians. 1985
PubMed ID: 3842206
Expression of the genes coding for the skeletal muscle and cardiac actions in the heart.
Mayer Y, Czosnek H, Zeelon PE, Yaffe D, Nudel U
Nucleic Acids Res. 1984
PubMed ID: 6546444
Isolation and characterization of cDNA clones for human skeletal muscle alpha actin.
Hanauer A, Levin M, Heilig R, Daegelen D, Kahn A, Mandel JL
Nucleic Acids Res. 1983
PubMed ID: 6190133
Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.
Gunning P, Ponte P, Okayama H, Engel J, Blau H, Kedes L
Mol Cell Biol. 1983
PubMed ID: 6865942
The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.
Czosnek H, Nudel U, Mayer Y, Barker PE, Pravtcheva DD, Ruddle FH, Yaffe D
EMBO J. 1983
PubMed ID: 6641707
Nucleotide sequence of the rat skeletal muscle actin gene.
Zakut R, Shani M, Givol D, Neuman S, Yaffe D, Nudel U
Nature. 1982
PubMed ID: 6287276
A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.
Minty AJ, Alonso S, Caravatti M, Buckingham ME
Cell. 1982
PubMed ID: 6897014
Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.
Nudel U, Katcoff D, Zakut R, Shani M, Carmon Y, Finer M, Czosnek H, Ginsburg I, Yaffe D
Proc Natl Acad Sci U S A. 1982
PubMed ID: 6953429
The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes.
Czosnek H, Nudel U, Shani M, Barker PE, Pravtcheva DD, Ruddle FH, Yaffe D
EMBO J. 1982
PubMed ID: 6897916
Skeletal muscle actin mRNA. Characterization of the 3' untranslated region.
Shani M, Nudel U, Zevin-Sonkin D, Zakut R, Givol D, Katcoff D, Carmon Y, Reiter J, Frischauf AM, Yaffe D
Nucleic Acids Res. 1981
PubMed ID: 6894330
Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA.
Minty AJ, Caravatti M, Robert B, Cohen A, Daubas P, Weydert A, Gros F, Buckingham ME
J Biol Chem. 1981
PubMed ID: 6256358
Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent manner.
Bretscher A, Weber K
Cell. 1980
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Construction of recombinant plasmids containing rat muscle actin and myosin light chain DNA sequences.
Katcoff D, Nudel U, Zevin-Sonkin D, Carmon Y, Shani M, Lehrach H, Frischauf AM, Yaffe D
Proc Natl Acad Sci U S A. 1980
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Interaction of adenylosuccinate synthetase with F-actin.
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My franchise was a teen-age lion's den.
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Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	58	11459	29437
EnsEMBL Gene(s)	ENSG00000143632	ENSMUSG00000031972	ENSRNOG00000017786
Unigene	Hs.1288	Mm.214950	Rn.82732
Homologene	ACTA1	Acta1	Acta1
OMIM	102610	N/A	N/A
GeneCards	ACTA1	N/A	N/A
Beta Cell Genomics	DT.102841501 DT.454774	DT.91536869 DT.94160441	N/A
Reactome	P68133	N/A	N/A
Plasma Peptide Atlas	ENSP00000224784	N/A	N/A
WikiGenes	58	11459	29437

External resources from NIDDK Consortium Interconnectivity Network Top Help

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Interactor	Interactor	Sources	Classification	Pubmed IDs
ACTA1	CDH2	BioGRID	empirical	12438242
ACTA1	OCLN	HPRD	empirical	9792688 10575001
ACTA1	FPGT-TNNI3K	HPRD	empirical	12721663
ACTA1	ACTR1B	HPRD	empirical	12857853
ACTA1	APC2	BioGRID	empirical	11691822
ACTA1	CORO2B	HPRD	empirical	10224093
ACTA1	GNB2L1	IntAct	empirical	17205597
ACTA1	KAT5	BioGRID	empirical	14966270
ACTA1	CCT4	HPRD, BioGRID	empirical	11580270
ACTA1	SORBS1	HPRD	empirical	17082770
ACTA1	CFL1	HPRD, BioGRID	empirical	11707283 10366597 11950878 21723825
ACTA1	PGRMC1	IntAct	empirical	17205597
ACTA1	MORF4L1	BioGRID	empirical	17573780
ACTA1	FGD4	HPRD	empirical	9668039 11429692
ACTA1	CNN1	HPRD, BioGRID	empirical	12033495 2455687 2161834
ACTA1	MIB2	BioGRID	empirical	14507647
ACTA1	CSNK1A1	BioGRID	empirical	12062430
ACTA1	CTNND1	HPRD	empirical	11969288
ACTA1	ADSS	HPRD	empirical	648524
ACTA1	XIRP1	HPRD	empirical	15454575
ACTA1	DHX9	BioGRID	empirical	11687588
ACTA1	DLG1	HPRD	empirical	9512503
ACTA1	DMD	HPRD, BioGRID	empirical	1544421 11259305
ACTA1	DNASE1	HPRD, BioGRID	empirical	11707283 2395459
ACTA1	DTNA	HPRD	empirical	12475945
ACTA1	EGFR	HPRD	empirical	1808202 1383230
ACTA1	AIF1	HPRD	empirical	12714565
ACTA1	CTTN	HPRD	empirical	7680654 11018051
ACTA1	EP300	BioGRID	empirical	16051665
ACTA1	EPB41	HPRD	empirical	11071908
ACTA1	EPB41L2	HPRD	empirical	12044158
ACTA1	EPS8	HPRD	empirical	11524436 12127568
ACTA1	AKT1	BioGRID	empirical	16568092
ACTA1	ETV6	BioGRID	empirical	9695962
ACTA1	ALB	IntAct	empirical	17205597
ACTA1	PHACTR1	HPRD, BioGRID	empirical	15107502
ACTA1	CCT5	HPRD, BioGRID	empirical	11580270
ACTA1	CYFIP1	HPRD	empirical	9417078
ACTA1	XPO6	BioGRID	empirical	14592989
ACTA1	DNMBP	HPRD, BioGRID	empirical	14506234
ACTA1	COTL1	HPRD, BioGRID	empirical	11583571 11297527
ACTA1	MACF1	HPRD	empirical	10601340 10559237 1074709
ACTA1	ABL1	HPRD	empirical	11309382
ACTA1	TES	BioGRID	empirical	12695497
ACTA1	TRAF3IP1	IntAct	empirical	20391533
ACTA1	GAS2	HPRD	empirical	10564664
ACTA1	GC	HPRD, MINT	empirical	12119014 12048248 7703225
ACTA1	KLHL20	HPRD, BioGRID	empirical	14668487
ACTA1	GRB2	BioGRID	empirical	12577067
ACTA1	FHOD1	HPRD	empirical	14576350 12665555
ACTA1	GSN	HPRD, MINT, BioGRID	empirical	10583954 10854330
ACTA1	HCLS1	HPRD	empirical	12534372
ACTA1	HDAC1	BioGRID	empirical	11102443
ACTA1	ANXA4	IntAct	empirical	17205597
ACTA1	ANXA13	IntAct	empirical	17205597
ACTA1	HSPA1L	IntAct	empirical	17205597
ACTA1	ITGA2	HPRD	empirical	7503723
ACTA1	ITPKA	HPRD	empirical	11468283
ACTA1	KCNMA1	MINT, IntAct	empirical	17065230 19423573
ACTA1	RPSA	IntAct	empirical	17205597
ACTA1	LASP1	HPRD	empirical	12571245
ACTA1	EPCAM	IntAct	empirical	17205597
ACTA1	ARRB1	IntAct	empirical	17620599
ACTA1	MAP1A	HPRD	empirical	7820861 7908020
ACTA1	NR3C2	HPRD	empirical	8612804
ACTA1	MYL1	HPRD	empirical	11707283
ACTA1	MYLK	HPRD	empirical	11481347
ACTA1	MYO6	HPRD	empirical	9852149
ACTA1	MYO7A	HPRD	empirical	12466270
ACTA1	MYO9B	HPRD	empirical	9490638
ACTA1	MYO10	HPRD	empirical	10984435
ACTA1	ATP1A1	IntAct	empirical	17205597
ACTA1	NRAP	BioGRID	empirical	10320340
ACTA1	PAK1	HPRD	empirical	9298982
ACTA1	TNNI3K	IntAct, BioGRID	empirical	12721663
ACTA1	PDPK1	MINT	empirical
ACTA1	PFN1	HPRD	empirical	8413665
ACTA1	PLD1	HPRD	empirical	12388543
ACTA1	CLIC5	HPRD, IntAct	empirical	10793131 17205597
ACTA1	POU5F1	BioGRID	empirical	21151833
ACTA1	PPP1CA	BioGRID	empirical	15107502
ACTA1	C20orf20	BioGRID	empirical	17573780
ACTA1	PARVA	HPRD	empirical	11171322
ACTA1	PRKCA	HPRD	empirical	10628374
ACTA1	PRKCD	HPRD	empirical	11415434
ACTA1	PRKCE	HPRD, BioGRID	empirical	8567732 11897493
ACTA1	ACTR10	HPRD	empirical	12857853
ACTA1	HDAC8	BioGRID	empirical	15772115
ACTA1	GNG12	IntAct	empirical	17205597
ACTA1	CTNNBL1	BioGRID	empirical	21385873
ACTA1	PTPN1	MINT	empirical	16291744
ACTA1	MARK4	BioGRID	empirical	14594945
ACTA1	ACTA1	HPRD	empirical	10366597 12048248
ACTA1	RAC1	HPRD	empirical	11027608
ACTA1	AFAP1	HPRD	empirical	10666339
ACTA1	RPS6KB1	BioGRID	empirical	15149849
ACTA1	RPS7	IntAct	empirical	17205597
ACTA1	S100A1	HPRD	empirical	9645951
ACTA1	S100A4	HPRD	empirical	14640694
ACTA1	TRAPPC2	IntAct	empirical	17205597
ACTA1	SMURF2	MINT	empirical	18157088
ACTA1	SLC2A4	IntAct	empirical	16396496
ACTA1	SMTN	HPRD	empirical	14523566
ACTA1	SMARCB1	BioGRID	empirical	16568092
ACTA1	SUMO3	BioGRID	empirical	22082260
ACTA1	FSCN1	HPRD	empirical	8999969
ACTA1	SPRR1A	HPRD	empirical	11850458
ACTA1	SPTA1	HPRD	empirical	2936753
ACTA1	SPTAN1	HPRD, BioGRID	empirical	7642559 11441066
ACTA1	SPTBN2	HPRD	empirical	11461920
ACTA1	SRC	MINT	empirical	16291744
ACTA1	TAGLN	HPRD, BioGRID	empirical	11053353
ACTA1	BTK	MINT, IntAct	empirical	21080425
ACTA1	TJP1	HPRD	empirical	9214391
ACTA1	TLN1	HPRD	empirical	10581178
ACTA1	ACTG1	IntAct	empirical	17205597
ACTA1	TSPAN8	IntAct	empirical	17205597
ACTA1	TMSB4X	HPRD, BioGRID	empirical	11812134 9153421
ACTA1	TNF	IntAct	empirical	17623297
ACTA1	TNNI1	HPRD	empirical	9724539
ACTA1	TNNI3	HPRD	empirical	12383268
ACTA1	TP53	HPRD	empirical	11821948
ACTA1	TPM2	BioGRID	empirical	17194691
ACTA1	TPM3	HPRD	empirical	11106625 12163017
ACTA1	TRIP6	BioGRID	empirical	14688263
ACTA1	TSC1	BioGRID	empirical	10806479
ACTA1	TTN	HPRD	empirical	9251807 11701614 15507486
ACTA1	UBC	BioGRID	empirical	18781797 21987572 21139048 21906983
ACTA1	UTRN	HPRD	empirical	12006649
ACTA1	VASP	HPRD	empirical	10882740 10438535
ACTA1	VAV1	HPRD	empirical	11839310
ACTA1	VCL	HPRD	empirical	7816144
ACTA1	VIL1	HPRD	empirical	3793760 6893424
ACTA1	EZR	IntAct	empirical	17205597
ACTA1	VIM	BioGRID	empirical	11441066
ACTA1	CACNB4	IntAct	empirical	19022416
ACTA1	MLPH	BioGRID	empirical	15059972
ACTA1	CALR	IntAct	empirical	17205597
ACTA1	TRIM63	MINT	empirical	18157088
ACTA1	AJUBA	HPRD	empirical	12417594
ACTA1	GAS7	HPRD	empirical	11795944
ACTA1	SCIN	BioGRID	empirical	12438125
ACTA1	DYNLL1	IntAct	empirical	14760703
ACTA1	CBL	BioGRID	empirical	21203488
ACTA1	CCIN	HPRD	empirical	11090452
ACTA1	IQGAP1	HPRD	empirical	9199170
ACTA1	HIP1R	HPRD	empirical	11889126
ACTA1	TMSB4Y	BioGRID	empirical	8416954
ACTA1	NEXN	HPRD	empirical	9832551
ACTA1	CYTH1	HPRD	empirical	11438522
ACTA1	PCYT1B	HPRD, BioGRID	empirical	11580270
ACTA1	KIF23	HPRD	empirical	11877456
ACTA1	MINPP1	HPRD	empirical	11536049
ACTA1	MORF4L2	BioGRID	empirical	17573780
ACTA1	USP6NL	HPRD	empirical	15152255
ACTA1	KIAA0101	BioGRID	empirical	21628590