SALL4

Summary Top Help

Gene Description:

sal-like 4 (Drosophila)

Synonyms:

DRRS, C330011P20Rik, AW536104, Tex20, ZNF797, Sall4, AA407717, C78083, HSAL4, dJ1112F19.1, C78563, SALL4, 5730441M18Rik, AL022809

Orthologs:

Human SALL4 (protein-coding), Mouse Sall4 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr20:50400581..50419048 (18.47 kb) View in Genome Browser

(Mouse) NCBIM37 - chr2:168573832..168593443 (19.61 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for SALL4:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: We do not have expression data for this gene.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas
			no data					no data	no data	no data	no data	no data

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: We do not have tissue expression data for this gene.

Interactions Top Help

Interactions Table for SALL4:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: 1

Gene Ontology: 19

Publications from PubMed Top Help

Publications: 109

Overexpression of SALL4 in lung cancer and its importance in cell proliferation.
Kobayashi D, Kuribayashi K, Tanaka M, Watanabe N
Oncol Rep. 2011
PubMed ID: 21725617
Immunohistochemical expression of embryonic stem cell markers in malignant rhabdoid tumors.
Deisch J, Raisanen J, Rakheja D
Pediatr Dev Pathol. 2011
PubMed ID: 21417895
Analysis of the SALL4 gene in patients with Duane retraction syndrome in a South Indian population.
Arya LK, Kumar AB, Shetty S, Perumalsamy V, Sundaresan P
Ophthalmic Genet. 2011
PubMed ID: 21405998
Immunoexpression of SALL4 in Wilms tumors and developing kidney.
Deisch J, Raisanen J, Rakheja D
Pathol Oncol Res. 2011
PubMed ID: 21258884
Dissecting the role of SALL4, a newly identified stem cell factor, in chronic myelogenous leukemia.
Lu J, Ma Y, Kong N, Alipio Z, Gao C, Krause DS, Silberstein LE, Chai L
Leukemia. 2011
PubMed ID: 21468036
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Exclusion of Sall 4 as the sex-determining gene in the Mandarin vole Microtus mandarinus mandarinus.
Chen Y, Ming Q, Zhu B
Hereditas. 2011
PubMed ID: 21756254
SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling.
Probst S, Kraemer C, Demougin P, Sheth R, Martin GR, Shiratori H, Hamada H, Iber D, Zeller R, Zuniga A
Development. 2011
PubMed ID: 21471156
SALL4 is essential for cancer cell proliferation and is overexpressed at early clinical stages in breast cancer.
Kobayashi D, Kuribayshi K, Tanaka M, Watanabe N
Int J Oncol. 2011
PubMed ID: 21274508
RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases.
Cao D, Liu A, Wang F, Allan RW, Mei K, Peng Y, Du J, Guo S, Abel TW, Lane Z, Ma J, Rodriguez M, Akhi S, Dehiya N, Li J
Mod Pathol. 2011
PubMed ID: 21057460
Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4.
Yang J, Aguila JR, Alipio Z, Lai R, Fink LM, Ma Y
J Hematol Oncol. 2011
PubMed ID: 21943195
Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA
PLoS One. 2011
PubMed ID: 21731673
SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes.
Jeong HW, Cui W, Yang Y, Lu J, He J, Li A, Song D, Guo Y, Liu BH, Chai L
PLoS One. 2011
PubMed ID: 21526180
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Differential roles of Sall4 isoforms in embryonic stem cell pluripotency.
Rao S, Zhen S, Roumiantsev S, McDonald LT, Yuan GC, Orkin SH
Mol Cell Biol. 2010
PubMed ID: 20837710
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Dev Cell. 2010
PubMed ID: 20412781
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.
Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu MM, Choudhary J
Cell Stem Cell. 2010
PubMed ID: 20362542
An Oct4-centered protein interaction network in embryonic stem cells.
van den Berg DL, Snoek T, Mullin NP, Yates A, Bezstarosti K, Demmers J, Chambers I, Poot RA
Cell Stem Cell. 2010
PubMed ID: 20362541
SALL4 represents fetal gut differentiation of gastric cancer, and is diagnostically useful in distinguishing hepatoid gastric carcinoma from hepatocellular carcinoma.
Ushiku T, Shinozaki A, Shibahara J, Iwasaki Y, Tateishi Y, Funata N, Fukayama M
Am J Surg Pathol. 2010
PubMed ID: 20182341
Cloning of complementary DNAs encoding structurally related homeoproteins from preimplantation mouse embryos: their involvement in the differentiation of embryonic stem cells.
Saito K, Abe H, Nakazawa M, Irokawa E, Watanabe M, Hosoi Y, Soma M, Kasuga K, Kojima I, Kobayashi M
Biol Reprod. 2010
PubMed ID: 20018908
An atlas of combinatorial transcriptional regulation in mouse and man.
Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
Cell. 2010
PubMed ID: 20211142
Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development.
Tian Y, Yuan L, Goss AM, Wang T, Yang J, Lepore JJ, Zhou D, Schwartz RJ, Patel V, Cohen ED, Morrisey EE
Dev Cell. 2010
PubMed ID: 20159597
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PLoS One. 2010
PubMed ID: 20634891
A novel SALL4/OCT4 transcriptional feedback network for pluripotency of embryonic stem cells.
Yang J, Gao C, Chai L, Ma Y
PLoS One. 2010
PubMed ID: 20505821
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Dev Cell. 2009
PubMed ID: 20059953
Diagnostic utility of SALL4 in primary germ cell tumors of the central nervous system: a study of 77 cases.
Mei K, Liu A, Allan RW, Wang P, Lane Z, Abel TW, Wei L, Cheng H, Guo S, Peng Y, Rakheja D, Wang M, Ma J, Rodriguez MM, Li J, Cao D
Mod Pathol. 2009
PubMed ID: 19820689
Overexpression of the novel oncogene SALL4 and activation of the Wnt/beta-catenin pathway in myelodysplastic syndromes.
Shuai X, Zhou D, Shen T, Wu Y, Zhang J, Wang X, Li Q
Cancer Genet Cytogenet. 2009
PubMed ID: 19781444
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.
Nishiyama A, Xin L, Sharov AA, Thomas M, Mowrer G, Meyers E, Piao Y, Mehta S, Yee S, Nakatake Y, Stagg C, Sharova L, Correa-Cerro LS, Bassey U, Hoang H, Kim E, Tapnio R, Qian Y, Dudekula D, Zalzman M, Li M, Falco G, Yang HT, Lee SL, Monti M, Stanghellini I, Islam MN, Nagaraja R, Goldberg I, Wang W, Longo DL, Schlessinger D, Ko MS
Cell Stem Cell. 2009
PubMed ID: 19796622
Diagnostic utility of SALL4 in extragonadal yolk sac tumors: an immunohistochemical study of 59 cases with comparison to placental-like alkaline phosphatase, alpha-fetoprotein, and glypican-3.
Wang F, Liu A, Peng Y, Rakheja D, Wei L, Xue D, Xue D, Allan RW, Molberg KH, Li J, Cao D
Am J Surg Pathol. 2009
PubMed ID: 19574883
Mutational analysis of SAL-Like 4 (SALL4) in Han Chinese women with premature ovarian failure.
Wang B, Li L, Ni F, Song J, Wang J, Mu Y, Ma X, Cao Y
Mol Hum Reprod. 2009
PubMed ID: 19581335
Genetic variation of SAL-Like 4 (SALL4) in ventricular septal defect.
Wang B, Li L, Xie X, Wang J, Yan J, Mu Y, Ma X
Int J Cardiol. 2009
PubMed ID: 19619907
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
Nimura K, Ura K, Shiratori H, Ikawa M, Okabe M, Schwartz RJ, Kaneda Y
Nature. 2009
PubMed ID: 19483677
SALL4 is a novel diagnostic marker for testicular germ cell tumors.
Cao D, Li J, Guo CC, Allan RW, Humphrey PA
Am J Surg Pathol. 2009
PubMed ID: 19390421
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.
Tsubooka N, Ichisaka T, Okita K, Takahashi K, Nakagawa M, Yamanaka S
Genes Cells. 2009
PubMed ID: 19476507
SALL4 is a novel sensitive and specific marker of ovarian primitive germ cell tumors and is particularly useful in distinguishing yolk sac tumor from clear cell carcinoma.
Cao D, Guo S, Allan RW, Molberg KH, Peng Y
Am J Surg Pathol. 2009
PubMed ID: 19295406
Gene and microRNA expression in p53-deficient day 8.5 mouse embryos.
Hosako H, Martin GS, Barrier M, Chen YA, Ivanov IV, Mirkes PE
Birth Defects Res A Clin Mol Teratol. 2009
PubMed ID: 19229884
Genome-wide Study of Single Nucleotide Polymorphisms Associated with Azoospermia and Severe Oligozoospermia.
Aston KI, Carrell DT
J Androl. 2009
PubMed ID: 19478329
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4.
Bard JD, Gelebart P, Amin HM, Young LC, Ma Y, Lai R
FASEB J. 2009
PubMed ID: 19151334
Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression.
Yuri S, Fujimura S, Nimura K, Takeda N, Toyooka Y, Fujimura Y, Aburatani H, Ura K, Koseki H, Niwa H, Nishinakamura R
Stem Cells. 2009
PubMed ID: 19350679
Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.
Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H
Gastroenterology. 2009
PubMed ID: 19185577
Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.
Kawakami Y, Uchiyama Y, Rodriguez Esteban C, Inenaga T, Koyano-Nakagawa N, Kawakami H, Marti M, Kmita M, Monaghan-Nichols P, Nishinakamura R, Izpisua Belmonte JC
Development. 2009
PubMed ID: 19168674
Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex.
Lu J, Jeong H, Kong N, Yang Y, Carroll J, Luo HR, Silberstein LE, Yupoma, Chai L
PLoS One. 2009
PubMed ID: 19440552
Regulation and function of Spalt proteins during animal development.
de Celis JF, Barrio R
Int J Dev Biol. 2009
PubMed ID: 19247946
Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells.
Yang J, Chai L, Fowles TC, Alipio Z, Xu D, Fink LM, Ward DC, Ma Y
Proc Natl Acad Sci U S A. 2008
PubMed ID: 19060217
[Expression of SALL4 and BMI-1 mRNA in acute leukemia].
Tang P, Sun H, Liu YF, Wang GY, Yin YF
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008
PubMed ID: 19099625
Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.
Lim CY, Tam WL, Zhang J, Ang HS, Jia H, Lipovich L, Ng HH, Wei CL, Sung WK, Robson P, Yang H, Lim B
Cell Stem Cell. 2008
PubMed ID: 18804426
Sall1, sall2, and sall4 are required for neural tube closure in mice.
Böhm J, Buck A, Borozdin W, Mannan AU, Matysiak-Scholze U, Adham I, Schulz-Schaeffer W, Floss T, Wurst W, Kohlhase J, Barrionuevo F
Am J Pathol. 2008
PubMed ID: 18818376
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo.
Uez N, Lickert H, Kohlhase J, de Angelis MH, Kühn R, Wurst W, Floss T
Genesis. 2008
PubMed ID: 18781635
SALL4 is a key regulator of survival and apoptosis in human leukemic cells.
Yang J, Chai L, Gao C, Fowles TC, Alipio Z, Dang H, Xu D, Fink LM, Ward DC, Ma Y
Blood. 2008
PubMed ID: 18487508
Molecular genetics of successful smoking cessation: convergent genome-wide association study results.
Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R, Lerman C
Arch Gen Psychiatry. 2008
PubMed ID: 18519826
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z
Nat Cell Biol. 2008
PubMed ID: 18454139
[Okihiro syndrome : Duane's syndrome and radial malformations of the limbs]
Haus AH, Kohlhase J, Käsmann B, Seitz B
Ophthalmologe. 2008
PubMed ID: 18299846
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming.
Wong CC, Gaspar-Maia A, Ramalho-Santos M, Reijo Pera RA
PLoS ONE. 2008
PubMed ID: 18414659
Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network.
Jakobsen JS, Braun M, Astorga J, Gustafson EH, Sandmann T, Karzynski M, Carlsson P, Furlong EE
Genes Dev. 2007
PubMed ID: 17908931
Novel approach for detecting global epigenetic alterations associated with tumor cell aneuploidy.
Habano W, Sugai T, Jiao YF, Nakamura S
Int J Cancer. 2007
PubMed ID: 17546590
EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W
Brief Funct Genomic Proteomic. 2007
PubMed ID: 17967808
Multigene deletions on chromosome 20q13.13-q13.2 including SALL4 result in an expanded phenotype of Okihiro syndrome plus developmental delay.
Borozdin W, Graham JM, Böhm D, Bamshad MJ, Spranger S, Burke L, Leipoldt M, Kohlhase J
Hum Mutat. 2007
PubMed ID: 17623483
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors.
Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17576928
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells.
Yang J, Chai L, Liu F, Fink LM, Lin P, Silberstein LE, Amin HM, Ward DC, Ma Y
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17557835
Synergistic cooperation of Sall4 and Cyclin D1 in transcriptional repression.
Böhm J, Kaiser FJ, Borozdin W, Depping R, Kohlhase J
Biochem Biophys Res Commun. 2007
PubMed ID: 17383611
IVIC syndrome is caused by a c.2607delA mutation in the SALL4 locus.
Paradisi I, Arias S
Am J Med Genet A. 2007
PubMed ID: 17256792
Mouse homolog of SALL1, a causative gene for Townes-Brocks syndrome, binds to A/T-rich sequences in pericentric heterochromatin via its C-terminal zinc finger domains.
Yamashita K, Sato A, Asashima M, Wang PC, Nishinakamura R
Genes Cells. 2007
PubMed ID: 17295837
A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis.
Warren M, Wang W, Spiden S, Chen-Murchie D, Tannahill D, Steel KP, Bradley A
Genesis. 2007
PubMed ID: 17216607
A protein interaction network for pluripotency of embryonic stem cells.
Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH
Nature. 2006
PubMed ID: 17093407
Murine inner cell mass-derived lineages depend on Sall4 function.
Elling U, Klasen C, Eisenberger T, Anlag K, Treier M
Proc Natl Acad Sci U S A. 2006
PubMed ID: 17060609
SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice.
Ma Y, Cui W, Yang J, Qu J, Di C, Amin HM, Lai R, Ritz J, Krause DS, Chai L
Blood. 2006
PubMed ID: 16763212
Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1.
Zhang J, Tam WL, Tong GQ, Wu Q, Chan HY, Soh BS, Lou Y, Yang J, Ma Y, Chai L, Ng HH, Lufkin T, Robson P, Lim B
Nat Cell Biol. 2006
PubMed ID: 16980957
Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells.
Wu Q, Chen X, Zhang J, Loh YH, Low TY, Zhang W, Zhang W, Sze SK, Lim B, Ng HH
J Biol Chem. 2006
PubMed ID: 16840789
The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.
Sakaki-Yumoto M, Kobayashi C, Sato A, Fujimura S, Matsumoto Y, Takasato M, Kodama T, Aburatani H, Asashima M, Yoshida N, Nishinakamura R
Development. 2006
PubMed ID: 16790473
The vertebrate spalt genes in development and disease.
Sweetman D, Münsterberg A
Dev Biol. 2006
PubMed ID: 16545361
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
A SALL4 zinc finger missense mutation predicted to result in increased DNA binding affinity is associated with cranial midline defects and mild features of Okihiro syndrome.
Miertus J, Borozdin W, Frecer V, Tonini G, Bertok S, Amoroso A, Miertus S, Kohlhase J
Hum Genet. 2006
PubMed ID: 16402211
A family with features overlapping Okihiro syndrome, hemifacial microsomia and isolated Duane anomaly caused by a novel SALL4 mutation.
Terhal P, Rösler B, Kohlhase J
Am J Med Genet A. 2006
PubMed ID: 16411190
Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.
Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG
Nat Genet. 2006
PubMed ID: 16380715
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.
Yoshikawa T, Piao Y, Zhong J, Matoba R, Carter MG, Wang Y, Goldberg I, Ko MS
Gene Expr Patterns. 2006
PubMed ID: 16325481
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
SALL4 mutations in Okihiro syndrome (Duane-radial ray syndrome), acro-renal-ocular syndrome, and related disorders.
Kohlhase J, Chitayat D, Kotzot D, Ceylaner S, Froster UG, Fuchs S, Montgomery T, Rösler B
Hum Mutat. 2005
PubMed ID: 16086360
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
No evidence of SALL4-mutations in isolated sporadic duane retraction "syndrome" (DURS).
Wabbels BK, Lorenz B, Kohlhase J
Am J Med Genet A. 2004
PubMed ID: 15386473
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
SALL4 deletions are a common cause of Okihiro and acro-renal-ocular syndromes and confirm haploinsufficiency as the pathogenic mechanism.
Borozdin W, Boehm D, Leipoldt M, Wilhelm C, Reardon W, Clayton-Smith J, Becker K, Mühlendyck H, Winter R, Giray O, Silan F, Kohlhase J
J Med Genet. 2004
PubMed ID: 15342710
Mutations in SALL4 in malformed father and daughter postulated previously due to reflect mutagenesis by thalidomide.
Kohlhase J, Holmes LB
Birth Defects Res A Clin Mol Teratol. 2004
PubMed ID: 15329836
Novel mutations in the gene SALL4 provide further evidence for acro-renal-ocular and Okihiro syndromes being allelic entities, and extend the phenotypic spectrum.
Borozdin W, Wright MJ, Hennekam RC, Hannibal MC, Crow YJ, Neumann TE, Kohlhase J
J Med Genet. 2004
PubMed ID: 15286162
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.
Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan J, Chan F, MacCarthy-Morrogh L, Ponder BA, Nagase H, Burn J, Ball S, Almeida M, Linardopoulos S, Balmain A
Nat Genet. 2003
PubMed ID: 12881723
Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy.
Kohlhase J, Schubert L, Liebers M, Rauch A, Becker K, Mohammed SN, Newbury-Ecob R, Reardon W
J Med Genet. 2003
PubMed ID: 12843316
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family.
Al-Baradie R, Yamada K, St Hilaire C, Chan WM, Andrews C, McIntosh N, Nakano M, Martonyi EJ, Raymond WR, Okumura S, Okihiro MM, Engle EC
Am J Hum Genet. 2002
PubMed ID: 12395297
Okihiro syndrome is caused by SALL4 mutations.
Kohlhase J, Heinrich M, Schubert L, Liebers M, Kispert A, Laccone F, Turnpenny P, Winter RM, Reardon W
Hum Mol Genet. 2002
PubMed ID: 12393809
Cloning and expression analysis of SALL4, the murine homologue of the gene mutated in Okihiro syndrome.
Kohlhase J, Heinrich M, Liebers M, Fröhlich Archangelo L, Reardon W, Kispert A
Cytogenet Genome Res. 2002
PubMed ID: 12826753
The DNA sequence and comparative analysis of human chromosome 20.
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J
Nature. 2001
PubMed ID: 11780052
The sequence of the human genome.
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X
Science. 2001
PubMed ID: 11181995
Functional annotation of a full-length mouse cDNA collection.
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Nature. 2001
PubMed ID: 11217851
Database resources of the National Center for Biotechnology Information.
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Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

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	Human	Mouse	Rat
Entrez Gene	57167	99377	N/A
EnsEMBL Gene(s)	ENSG00000101115	ENSMUSG00000027547	N/A
Unigene	Hs.517113	Mm.434054	N/A
Homologene	SALL4	Sall4	N/A
OMIM	607343	N/A	N/A
GeneCards	SALL4	N/A	N/A
Beta Cell Genomics	DT.100716069 DT.108738	DT.102552071 DT.110652882 DT.531333	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	57167	99377	N/A

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Interactor	Interactor	Sources	Classification	Pubmed IDs
SALL4	RUVBL2	BioGRID	empirical	20362541
SALL4	CHD4	BioGRID	empirical	20362541
SALL4	WDR5	BioGRID	empirical	20362541
SALL4	NACC1	BioGRID	empirical	20362541 17093407
SALL4	CTBP2	BioGRID	empirical	20362541
SALL4	NR0B1	BioGRID	empirical	20362541 17093407
SALL4	ESRRB	BioGRID	empirical	20362541
SALL4	EWSR1	BioGRID	empirical	20362541
SALL4	FOXE3	BioGRID	empirical	20211142
SALL4	ZNF281	BioGRID	empirical	17093407
SALL4	SALL3	BioGRID	empirical	20362541
SALL4	TFCP2L1	BioGRID	empirical	20362541
SALL4	HDAC1	BioGRID	empirical	20362541
SALL4	HDAC2	BioGRID	empirical	20362541
SALL4	HOXC4	BioGRID	empirical	20211142
SALL4	KIF5A	BioGRID	empirical	20362541
SALL4	ZNF219	BioGRID	empirical	20362541
SALL4	CXXC5	BioGRID	empirical	20362541
SALL4	MBD3	BioGRID	empirical	20362541
SALL4	L1TD1	BioGRID	empirical	20362541
SALL4	POU5F1	IntAct, BioGRID	empirical	20362542 19060217 20362541
SALL4	GATAD2A	BioGRID	empirical	20362541
SALL4	VRTN	BioGRID	empirical	20362541
SALL4	GATAD2B	BioGRID	empirical	20362541
SALL4	MTA3	BioGRID	empirical	20362541
SALL4	ZBTB2	BioGRID	empirical	20362541
SALL4	BEND3	BioGRID	empirical	20362541
SALL4	RBBP4	BioGRID	empirical	20362541
SALL4	RBBP7	BioGRID	empirical	20362541
SALL4	DPF2	BioGRID	empirical	20362541
SALL4	SALL2	BioGRID	empirical	20362541
SALL4	SALL1	BioGRID	empirical	20362541
SALL4	SET	BioGRID	empirical	20362541
SALL4	SMARCA4	BioGRID	empirical	20362541
SALL4	SMARCB1	BioGRID	empirical	20362541
SALL4	SMARCC1	BioGRID	empirical	20362541
SALL4	SMARCD1	BioGRID	empirical	20362541
SALL4	TFCP2	BioGRID	empirical	20362541
SALL4	ZNF143	BioGRID	empirical	20362541
SALL4	NANOG	IntAct, BioGRID	empirical	17093407 19060217 16840789 18454139
SALL4	GRHL2	BioGRID	empirical	20362541
SALL4	USP9X	BioGRID	empirical	20362541
SALL4	ARID1A	BioGRID	empirical	20362541
SALL4	ACTL6A	BioGRID	empirical	20362541
SALL4	MBD2	BioGRID	empirical	20362541
SALL4	MTA1	BioGRID	empirical	20362541
SALL4	MTA2	BioGRID	empirical	20362541