Home PSMB6
|
Regions Overlapping this Feature:
Mouse: 1
Linkage Regions: 1 Available
Linkage Regions: 1 Available
| Locus | Species | Chromosomal Location | Mb | Number of genes | Linkage and Congenic Studies |
|---|---|---|---|---|---|
| Idd4.1 | Mouse | chr11:69761993..71151314 | 1.39 | 60 |
(Human) GRCh37 - chr17:4699439..4701798 (2.36 kb) View in Genome Browser
(Mouse) NCBIM37 - chr11:70338859..70341360 (2.50 kb) View in Genome Browser
(Rat) RGSC3.4 - chr10:57370395..57372706 (2.31 kb) View in Genome Browser
HaemAtlas Expression Table for PSMB6:|
Expression Legend
|
|
|
Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
Expression Legend
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Expression Legend
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for PSMB6:The PSMB6 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| PSMB6 | PSME3 | Reactome | predicted | |
| PSMB6 | PSMD14 | Reactome | predicted | |
| PSMB6 | PSMB11 | Reactome | predicted | |
| PSMB6 | PSMA8 | Reactome | predicted | |
| PSMB6 | FBL | HPRD | empirical | 12388758 |
| PSMB6 | EZH2 | HPRD, MINT, IntAct | empirical | 16169070 |
| PSMB6 | PSME4 | Reactome | predicted | |
| PSMB6 | HLA-B | IntAct | empirical | 17353931 |
| PSMB6 | POMP | HPRD, MINT, IntAct | empirical | 14733938 17948026 |
| PSMB6 | UCHL5 | IntAct, BioGRID | empirical | 19615732 18922472 |
| PSMB6 | PLK1 | HPRD, BioGRID | empirical | 11205743 |
| PSMB6 | POU5F1 | IntAct | empirical | 20362542 |
| PSMB6 | PPP2R1A | IntAct | empirical | 16857963 |
| PSMB6 | PSMA1 | IntAct, Reactome, Sanger Interaction Map | empirical | 12376572 16857966 15345047 |
| PSMB6 | PSMA2 | IntAct, BioGRID, Reactome | empirical | 15887188 12376572 |
| PSMB6 | PSMA3 | IntAct, Reactome | empirical | 16857966 |
| PSMB6 | PSMA4 | Reactome | predicted | |
| PSMB6 | PSMA5 | Reactome | predicted | |
| PSMB6 | PSMA6 | Reactome, Sanger Interaction Map | predicted | 15345047 |
| PSMB6 | PSMA7 | Reactome | predicted | |
| PSMB6 | PSMB1 | Reactome | predicted | |
| PSMB6 | PSMB2 | Reactome | predicted | |
| PSMB6 | PSMB3 | Reactome | predicted | |
| PSMB6 | PSMB4 | Reactome | predicted | |
| PSMB6 | PSMB5 | Reactome, Sanger Interaction Map | predicted | 15345047 |
| PSMB6 | PSMB7 | HPRD, MINT, IntAct, Reactome | empirical | 14733938 17948026 |
| PSMB6 | PSMB8 | Reactome | predicted | |
| PSMB6 | PSMB9 | Reactome | predicted | |
| PSMB6 | PSMB10 | Reactome | predicted | |
| PSMB6 | PSMC1 | Reactome | predicted | |
| PSMB6 | PSMC2 | Reactome | predicted | |
| PSMB6 | PSMC3 | Reactome | predicted | |
| PSMB6 | PSMC4 | Reactome | predicted | |
| PSMB6 | PSMC5 | Reactome | predicted | |
| PSMB6 | PSMC6 | Reactome | predicted | |
| PSMB6 | PSMD1 | Reactome | predicted | |
| PSMB6 | PSMD2 | Reactome | predicted | |
| PSMB6 | PSMD3 | Reactome | predicted | |
| PSMB6 | PSMD4 | Reactome | predicted | |
| PSMB6 | PSMD5 | Reactome | predicted | |
| PSMB6 | PSMD7 | Reactome | predicted | |
| PSMB6 | PSMD8 | Reactome | predicted | |
| PSMB6 | PSMD9 | Reactome | predicted | |
| PSMB6 | PSMD10 | Reactome | predicted | |
| PSMB6 | PSMD11 | Reactome | predicted | |
| PSMB6 | PSMD12 | Reactome | predicted | |
| PSMB6 | PSMD13 | Reactome | predicted | |
| PSMB6 | PSME1 | Reactome | predicted | |
| PSMB6 | PSME2 | Reactome | predicted | |
| PSMB6 | PTPRA | Sanger Interaction Map | predicted | 15345047 |
| PSMB6 | SLC2A4 | IntAct | empirical | 16396496 |
| PSMB6 | TRAF6 | MINT, IntAct | empirical | 14743216 |
| PSMB6 | UBC | BioGRID | empirical | 16196087 21987572 21139048 21890473 21906983 |
| PSMB6 | PSMF1 | Reactome | predicted | |
| PSMB6 | IKBKE | IntAct | empirical | 17353931 |
| PSMB6 | IQCB1 | IntAct | empirical | 21565611 |
| PSMB6 | KIAA0101 | BioGRID | empirical | 21628590 |
| PSMB6 | PSMD6 | Reactome | predicted |
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
|
Publications: 74
-
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR
J Biol Chem. 2011
PubMed ID: 21987572
-
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
-
LPS-induced formation of immunoproteasomes: TNF-α and nitric oxide production are regulated by altered composition of proteasome-active sites.
Reis J, Guan XQ, Kisselev AF, Papasian CJ, Qureshi AA, Morrison DC, Van Way CW, Vogel SN, Qureshi N
Cell Biochem Biophys. 2011
PubMed ID: 21455682
-
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
-
PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.
Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S
Mol Cell Biol. 2010
PubMed ID: 20498273
-
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.
Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu MM, Choudhary J
Cell Stem Cell. 2010
PubMed ID: 20362542
-
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell. 2009
PubMed ID: 19615732
-
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
-
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
-
Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.
Forsman A, Rüetschi U, Ekholm J, Rymo L
J Proteome Res. 2008
PubMed ID: 18457437
-
Tissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: enhanced activity for degradation of abnormal protein.
Kwak MK, Huang B, Chang H, Kim JA, Kensler TW
Life Sci. 2007
PubMed ID: 17521679
-
Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
Wang X, Chen CF, Baker PR, Chen PL, Kaiser P, Huang L
Biochemistry. 2007
PubMed ID: 17323924
-
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
-
Large-scale analysis of the human ubiquitin-related proteome.
Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T, Nakayama KI
Proteomics. 2005
PubMed ID: 16196087
-
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
-
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
-
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
-
Comprehensive gene expression profiling of anaplastic thyroid cancers with cDNA microarray of 25 344 genes.
Onda M, Emi M, Yoshida A, Miyamoto S, Akaishi J, Asaka S, Mizutani K, Shimizu K, Nagahama M, Ito K, Tanaka T, Tsunoda T
Endocr Relat Cancer. 2004
PubMed ID: 15613457
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
-
Mammalian Cdh1/Fzr mediates its own degradation.
Listovsky T, Oren YS, Yudkovsky Y, Mahbubani HM, Weiss AM, Lebendiker M, Brandeis M
EMBO J. 2004
PubMed ID: 15029244
-
A genomic analysis of rat proteases and protease inhibitors.
Puente XS, López-Otín C
Genome Res. 2004
PubMed ID: 15060002
-
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
-
A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
García-Frigola C, Burgaya F, Calbet M, López-Domènech G, de Lecea L, Soriano E
Brain Res Mol Brain Res. 2004
PubMed ID: 15010206
-
Protein-protein interactions among human 20S proteasome subunits and proteassemblin.
Jayarapu K, Griffin TA
Biochem Biophys Res Commun. 2004
PubMed ID: 14733938
-
The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G.
Conticello SG, Harris RS, Neuberger MS
Curr Biol. 2003
PubMed ID: 14614829
-
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.
Yu X, Yu Y, Liu B, Luo K, Kong W, Mao P, Yu XF
Science. 2003
PubMed ID: 14564014
-
The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.
Shindo K, Takaori-Kondo A, Kobayashi M, Abudu A, Fukunaga K, Uchiyama T
J Biol Chem. 2003
PubMed ID: 12970355
-
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.
Kao S, Khan MA, Miyagi E, Plishka R, Buckler-White A, Strebel K
J Virol. 2003
PubMed ID: 14557625
-
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation.
Marin M, Rose KM, Kozak SL, Kabat D
Nat Med. 2003
PubMed ID: 14528301
-
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif.
Sheehy AM, Gaddis NC, Malim MH
Nat Med. 2003
PubMed ID: 14528300
-
Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits.
Apcher GS, Heink S, Zantopf D, Kloetzel PM, Schmid HP, Mayer RJ, Krüger E
FEBS Lett. 2003
PubMed ID: 14550573
-
HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.
Stopak K, de Noronha C, Yonemoto W, Greene WC
Mol Cell. 2003
PubMed ID: 14527406
-
Virology. Weapons of mutational destruction.
KewalRamani VN, Coffin JM
Science. 2003
PubMed ID: 12920286
-
Death by deamination: a novel host restriction system for HIV-1.
Goff SP
Cell. 2003
PubMed ID: 12914693
-
Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.
Mariani R, Chen D, Schröfelbauer B, Navarro F, König R, Bollman B, Münk C, Nymark-McMahon H, Landau NR
Cell. 2003
PubMed ID: 12859895
-
Good to CU.
Gu Y, Sundquist WI
Nature. 2003
PubMed ID: 12840737
-
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Mangeat B, Turelli P, Caron G, Friedli M, Perrin L, Trono D
Nature. 2003
PubMed ID: 12808466
-
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA.
Zhang H, Yang B, Pomerantz RJ, Zhang C, Arunachalam SC, Gao L
Nature. 2003
PubMed ID: 12808465
-
DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses.
Harris RS, Sheehy AM, Craig HM, Malim MH, Neuberger MS
Nat Immunol. 2003
PubMed ID: 12830140
-
DNA deamination mediates innate immunity to retroviral infection.
Harris RS, Bishop KN, Sheehy AM, Craig HM, Petersen-Mahrt SK, Watt IN, Neuberger MS, Malim MH
Cell. 2003
PubMed ID: 12809610
-
Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.
Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK
Dev Cell. 2003
PubMed ID: 12791267
-
Hypermutation of HIV-1 DNA in the absence of the Vif protein.
Lecossier D, Bouchonnet F, Clavel F, Hance AJ
Science. 2003
PubMed ID: 12750511
-
Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions.
Gaddis NC, Chertova E, Sheehy AM, Henderson LE, Malim MH
J Virol. 2003
PubMed ID: 12719574
-
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
-
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
-
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
-
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.
Huang X, Seifert U, Salzmann U, Henklein P, Preissner R, Henke W, Sijts AJ, Kloetzel PM, Dubiel W
J Mol Biol. 2002
PubMed ID: 12419264
-
Subcellular recruitment of fibrillarin to nucleoplasmic proteasomes: implications for processing of a nucleolar autoantigen.
Chen M, Rockel T, Steinweger G, Hemmerich P, Risch J, von Mikecz A
Mol Biol Cell. 2002
PubMed ID: 12388758
-
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein.
Sheehy AM, Gaddis NC, Choi JD, Malim MH
Nature. 2002
PubMed ID: 12167863
-
Mapping and structural dissection of human 20 S proteasome using proteomic approaches.
Claverol S, Burlet-Schiltz O, Girbal-Neuhauser E, Gairin JE, Monsarrat B
Mol Cell Proteomics. 2002
PubMed ID: 12376572
-
Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Piao Y, Ko NT, Lim MK, Ko MS
Genome Res. 2001
PubMed ID: 11544199
-
Genetic, physical, and transcript map of the Ltxs1 region of mouse chromosome 11.
Watters JW, Dietrich WF
Genomics. 2001
PubMed ID: 11318612
-
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.
Geley S, Kramer E, Gieffers C, Gannon J, Peters JM, Hunt T
J Cell Biol. 2001
PubMed ID: 11285280
-
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
-
Polo-like kinase interacts with proteasomes and regulates their activity.
Feng Y, Longo DL, Ferris DK
Cell Growth Differ. 2001
PubMed ID: 11205743
-
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
-
Large-scale screen for genes involved in gonad development.
Wertz K, Herrmann BG
Mech Dev. 2000
PubMed ID: 11044607
-
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
-
Degradation of HIV-1 integrase by the N-end rule pathway.
Mulder LC, Muesing MA
J Biol Chem. 2000
PubMed ID: 10893419
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
-
Evidence for a newly discovered cellular anti-HIV-1 phenotype.
Simon JH, Gaddis NC, Fouchier RA, Malim MH
Nat Med. 1998
PubMed ID: 9846577
-
An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein.
Madani N, Kabat D
J Virol. 1998
PubMed ID: 9811770
-
The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.
Hayashi M, Ishibashi T, Tanaka K, Kasahara M
J Immunol. 1997
PubMed ID: 9300697
-
HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation.
Seeger M, Ferrell K, Frank R, Dubiel W
J Biol Chem. 1997
PubMed ID: 9079628
-
Structure and functions of the 20S and 26S proteasomes.
Coux O, Tanaka K, Goldberg AL
Annu Rev Biochem. 1996
PubMed ID: 8811196
-
Characterization and mapping of the gene encoding mouse proteasome subunit DELTA (Lmp19).
Woodward EC, Monaco JJ
Immunogenetics. 1995
PubMed ID: 7797265
-
Human proteasome subunits from 2-dimensional gels identified by partial sequencing.
Kristensen P, Johnsen AH, Uerkvitz W, Tanaka K, Hendil KB
Biochem Biophys Res Commun. 1994
PubMed ID: 7811265
-
cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y.
Akiyama K, Yokota K, Kagawa S, Shimbara N, Tamura T, Akioka H, Nothwang HG, Noda C, Tanaka K, Ichihara A
Science. 1994
PubMed ID: 8066462
-
Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.
Früh K, Gossen M, Wang K, Bujard H, Peterson PA, Yang Y
EMBO J. 1994
PubMed ID: 8045254
-
Replacement of proteasome subunits X and Y by LMP7 and LMP2 induced by interferon-gamma for acquirement of the functional diversity responsible for antigen processing.
Akiyama K, Kagawa S, Tamura T, Shimbara N, Takashina M, Kristensen P, Hendil KB, Tanaka K, Ichihara A
FEBS Lett. 1994
PubMed ID: 8163024
-
Molecular cloning of cDNAs for rat proteasomes: deduced primary structures of four other subunits.
Tamura T, Shimbara N, Aki M, Ishida N, Bey F, Scherrer K, Tanaka K, Ichihara A
J Biochem. 1992
PubMed ID: 1491007
-
The primary structures of four subunits of the human, high-molecular-weight proteinase, macropain (proteasome), are distinct but homologous.
DeMartino GN, Orth K, McCullough ML, Lee LW, Munn TZ, Moomaw CR, Dawson PA, Slaughter CA
Biochim Biophys Acta. 1991
PubMed ID: 1888762
-
N-terminal sequence similarities between components of the multicatalytic proteinase complex.
Lilley KS, Davison MD, Rivett AJ
FEBS Lett. 1990
PubMed ID: 2335214
-
Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome).
Lee LW, Moomaw CR, Orth K, McGuire MJ, DeMartino GN, Slaughter CA
Biochim Biophys Acta. 1990
PubMed ID: 2306472
Model Organism Phenotype Links
|
Relevant resources: