PSMB1

Summary Top Help

Gene Description:

proteasome (prosome, macropain) subunit, beta type, 1; proteasome (prosome, macropain) subunit, beta type 1

Synonyms:

HC5, Psmb1, PSMB1, C81484, Lmpc5, AA409053, PSC5, PMSB1

Orthologs:

Human PSMB1 (protein-coding), Mouse Psmb1 (protein-coding), Rat Psmb1 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Mouse: 1

Linkage Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd23	Mouse	chr17:3924615..26319104	22.39	376

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr6:170780107..170862429 (82.32 kb) View in Genome Browser

(Mouse) NCBIM37 - chr17:15612685..15635240 (22.55 kb) View in Genome Browser

(Rat) RGSC3.4 - chr1:54369775..54388816 (194 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for PSMB1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for PSMB1:

The PSMB1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.

The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.

Interactor	Interactor	Sources	Classification	Pubmed IDs
PSMB1	PSME3	Reactome	predicted
PSMB1	PSMD14	Reactome	predicted
PSMB1	WASF3	Sanger Interaction Map	predicted	15345047
PSMB1	CLP1	Sanger Interaction Map	predicted	15345047
PSMB1	GABARAP	IntAct	empirical	20562859
PSMB1	EXOSC6	HPRD, BioGRID	empirical	15231747
PSMB1	PSMB11	Reactome	predicted
PSMB1	PSMA8	Reactome	predicted
PSMB1	DCP2	HPRD, IntAct, BioGRID	empirical	15231747
PSMB1	EIF2B1	Sanger Interaction Map	predicted	15345047
PSMB1	EPB41	IntAct	empirical	17353931
PSMB1	FANCG	BioGRID	empirical	14499622
PSMB1	PASK	IntAct, BioGRID	empirical	17353931
PSMB1	PSME4	Reactome	predicted
PSMB1	GABARAPL1	IntAct	empirical	20562859
PSMB1	FTSJ1	IntAct	empirical	17353931
PSMB1	DSTYK	IntAct, BioGRID	empirical	17353931
PSMB1	HLA-B	IntAct	empirical	17353931
PSMB1	ILK	IntAct	empirical	17353931
PSMB1	EIF6	IntAct	empirical	17353931
PSMB1	MTHFR	Sanger Interaction Map	predicted	15345047
PSMB1	MYC	IntAct, BioGRID	empirical	17314511
PSMB1	ACLY	Sanger Interaction Map	predicted	15345047
PSMB1	WRAP73	IntAct	empirical	17353931
PSMB1	SERPINB2	HPRD	empirical	14732874
PSMB1	PCK1	BioGRID	empirical	21726808
PSMB1	INSIG2	BioGRID	empirical	19815544
PSMB1	POMP	HPRD, MINT, IntAct	empirical	14733938 17948026
PSMB1	UCHL5	IntAct	empirical	19490896 18922472
PSMB1	PLK1	HPRD, BioGRID	empirical	11205743
PSMB1	PPP2R1A	IntAct	empirical	16857963
PSMB1	PSMA1	IntAct, Reactome, Sanger Interaction Map	empirical	12376572 16857966 15345047
PSMB1	PSMA2	IntAct, BioGRID, Reactome, Sanger Interaction Map	empirical	15887188 12376572 15345047
PSMB1	PSMA3	Reactome	predicted
PSMB1	PSMA4	Reactome, Sanger Interaction Map	predicted	15345047
PSMB1	PSMA5	Reactome	predicted
PSMB1	PSMA6	Reactome, Sanger Interaction Map	predicted	15345047
PSMB1	PSMA7	Reactome, Sanger Interaction Map	predicted	15345047
PSMB1	PSMB2	MINT, Reactome, Sanger Interaction Map	empirical	17948026 15345047
PSMB1	PSMB3	HPRD, MINT, IntAct, Reactome, Sanger Interaction Map	empirical	14733938 17948026 15345047
PSMB1	PSMB4	Reactome	predicted
PSMB1	PSMB5	HPRD, MINT, IntAct, Reactome, Sanger Interaction Map	empirical	14733938 17948026 15345047
PSMB1	PSMB6	Reactome	predicted
PSMB1	PSMB7	HPRD, MINT, IntAct, Reactome	empirical	14733938 17948026 20723761
PSMB1	PSMB8	IntAct, Reactome	empirical	14733938
PSMB1	PSMB9	Reactome	predicted
PSMB1	PSMB10	Reactome	predicted
PSMB1	PSMC1	Reactome	predicted
PSMB1	PSMC2	Reactome	predicted
PSMB1	PSMC3	Reactome	predicted
PSMB1	PSMC4	Reactome	predicted
PSMB1	PSMC5	Reactome	predicted
PSMB1	PSMC6	Reactome	predicted
PSMB1	PSMD1	Reactome	predicted
PSMB1	PSMD2	Reactome	predicted
PSMB1	PSMD3	Reactome	predicted
PSMB1	PSMD4	MINT, Reactome	empirical	16990800
PSMB1	PSMD5	Reactome	predicted
PSMB1	PSMD7	Reactome	predicted
PSMB1	PSMD8	Reactome	predicted
PSMB1	PSMD9	Reactome	predicted
PSMB1	PSMD10	Reactome	predicted
PSMB1	PSMD11	Reactome	predicted
PSMB1	PSMD12	Reactome	predicted
PSMB1	PSMD13	Reactome	predicted
PSMB1	PSME1	Reactome	predicted
PSMB1	PSME2	Reactome	predicted
PSMB1	KLHL8	Sanger Interaction Map	predicted	15345047
PSMB1	RAD23B	IntAct	empirical	20178748
PSMB1	BCL3	BioGRID	empirical	20558726
PSMB1	SLC2A4	IntAct	empirical	16396496
PSMB1	UBC	BioGRID	empirical	16196087 18781797 21987572 21963094 12938929 21139048 21890473 21906983
PSMB1	VHL	IntAct, BioGRID	empirical	17353931
PSMB1	CASP4	IntAct, BioGRID	empirical	17353931
PSMB1	TNFRSF14	IntAct	empirical	17353931
PSMB1	RIOK3	IntAct, BioGRID	empirical	17353931
PSMB1	TSC22D1	IntAct	empirical	17353931
PSMB1	ATP6V0D1	Sanger Interaction Map	predicted	15345047
PSMB1	CIAO1	IntAct	empirical	17353931
PSMB1	PSMF1	Reactome	predicted
PSMB1	IKBKE	IntAct	empirical	17353931
PSMB1	IQCB1	IntAct	empirical	21565611
PSMB1	KIAA0101	BioGRID	empirical	21628590
PSMB1	PSMD6	Reactome	predicted

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 1

Biocarta: None available

Reactome: 47

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	REACT_6954
APC/C-mediated degradation of cell cycle proteins	REACT_6828
APC/C:Cdc20 mediated degradation of mitotic proteins	REACT_6781
APC/C:Cdc20 mediated degradation of Securin	REACT_6871
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	REACT_6761
Apoptosis	REACT_578
Assembly of the pre-replicative complex	REACT_2243
Autodegradation of Cdh1 by Cdh1:APC/C	REACT_6785
Autodegradation of the E3 ubiquitin ligase COP1	REACT_20549
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	REACT_6850
CDK-mediated phosphorylation and removal of Cdc6	REACT_1221
CDT1 association with the CDC6:ORC:origin complex	REACT_1949
Cell Cycle Checkpoints	REACT_1538
Cell Cycle, Mitotic	REACT_152
Cyclin A:Cdk2-associated events at S phase entry	REACT_9029
Cyclin E associated events during G1/S transition	REACT_1574
Degradation of beta-catenin by the destruction complex	REACT_11063
DNA Replication	REACT_383
DNA Replication Pre-Initiation	REACT_734
G1/S DNA Damage Checkpoints	REACT_2254
G1/S Transition	REACT_1783
M/G1 Transition	REACT_1725
Metabolism of amino acids and derivatives	REACT_13
Mitotic G1-G1/S phases	REACT_21267
Mitotic M-M/G1 phases	REACT_21300
Orc1 removal from chromatin	REACT_1156
p53-Dependent G1 DNA Damage Response	REACT_1625
p53-Dependent G1/S DNA damage checkpoint	REACT_85
p53-Independent DNA Damage Response	REACT_2160
p53-Independent G1/S DNA damage checkpoint	REACT_1208
Regulation of activated PAK-2p34 by proteasome mediated degradation	REACT_13464
Regulation of APC/C activators between G1/S and early anaphase	REACT_6837
Regulation of Apoptosis	REACT_13648
Regulation of DNA replication	REACT_829
Regulation of mitotic cell cycle	REACT_21279
Regulation of ornithine decarboxylase (ODC)	REACT_13565
Removal of licensing factors from origins	REACT_207
S Phase	REACT_899
SCF(Skp2)-mediated degradation of p27/p21	REACT_9003
SCF-beta-TrCP mediated degradation of Emi1	REACT_6821
Signaling by Wnt	REACT_11045
Stabilization of p53	REACT_309
Switching of origins to a post-replicative state	REACT_2148
Synthesis of DNA	REACT_2014
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	REACT_1614
Ubiquitin-dependent degradation of Cyclin D	REACT_938
Ubiquitin-dependent degradation of Cyclin D1	REACT_4

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 34

KEGG Network: 1
Proteasome	Human - 3050	Mouse - 3050	Rat - 3050

Biocarta: None available

Reactome: 47
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	REACT_6954
APC/C-mediated degradation of cell cycle proteins	REACT_6828
APC/C:Cdc20 mediated degradation of mitotic proteins	REACT_6781
APC/C:Cdc20 mediated degradation of Securin	REACT_6871
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	REACT_6761
Apoptosis	REACT_578
Assembly of the pre-replicative complex	REACT_2243
Autodegradation of Cdh1 by Cdh1:APC/C	REACT_6785
Autodegradation of the E3 ubiquitin ligase COP1	REACT_20549
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	REACT_6850
CDK-mediated phosphorylation and removal of Cdc6	REACT_1221
CDT1 association with the CDC6:ORC:origin complex	REACT_1949
Cell Cycle Checkpoints	REACT_1538
Cell Cycle, Mitotic	REACT_152
Cyclin A:Cdk2-associated events at S phase entry	REACT_9029
Cyclin E associated events during G1/S transition	REACT_1574
Degradation of beta-catenin by the destruction complex	REACT_11063
DNA Replication	REACT_383
DNA Replication Pre-Initiation	REACT_734
G1/S DNA Damage Checkpoints	REACT_2254
G1/S Transition	REACT_1783
M/G1 Transition	REACT_1725
Metabolism of amino acids and derivatives	REACT_13
Mitotic G1-G1/S phases	REACT_21267
Mitotic M-M/G1 phases	REACT_21300
Orc1 removal from chromatin	REACT_1156
p53-Dependent G1 DNA Damage Response	REACT_1625
p53-Dependent G1/S DNA damage checkpoint	REACT_85
p53-Independent DNA Damage Response	REACT_2160
p53-Independent G1/S DNA damage checkpoint	REACT_1208
Regulation of activated PAK-2p34 by proteasome mediated degradation	REACT_13464
Regulation of APC/C activators between G1/S and early anaphase	REACT_6837
Regulation of Apoptosis	REACT_13648
Regulation of DNA replication	REACT_829
Regulation of mitotic cell cycle	REACT_21279
Regulation of ornithine decarboxylase (ODC)	REACT_13565
Removal of licensing factors from origins	REACT_207
S Phase	REACT_899
SCF(Skp2)-mediated degradation of p27/p21	REACT_9003
SCF-beta-TrCP mediated degradation of Emi1	REACT_6821
Signaling by Wnt	REACT_11045
Stabilization of p53	REACT_309
Switching of origins to a post-replicative state	REACT_2148
Synthesis of DNA	REACT_2014
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	REACT_1614
Ubiquitin-dependent degradation of Cyclin D	REACT_938
Ubiquitin-dependent degradation of Cyclin D1	REACT_4

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 34
Cell cycle checkpoint	GO:0000075
G1/S transition of mitotic cell cycle	GO:0000082
S phase of mitotic cell cycle	GO:0000084
Protein polyubiquitination	GO:0000209
M/G1 transition of mitotic cell cycle	GO:0000216
Mitotic cell cycle	GO:0000278
Proteasome complex	GO:0000502
Antigen processing and presentation of peptide antigen via MHC class I	GO:0002474
Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	GO:0002479
Threonine-type endopeptidase activity	GO:0004298
Protein binding	GO:0005515
Nucleus	GO:0005634
Nucleoplasm	GO:0005654
Cytoplasm	GO:0005737
Cytosol	GO:0005829
Proteasome core complex	GO:0005839
Regulation of cellular amino acid metabolic process	GO:0006521
Apoptotic process	GO:0006915
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	GO:0006977
Peptidase activity	GO:0008233
Gene expression	GO:0010467
Viral reproduction	GO:0016032
RNA metabolic process	GO:0016070
MRNA metabolic process	GO:0016071
Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	GO:0031145
Cellular nitrogen compound metabolic process	GO:0034641
Antigen processing and presentation of exogenous peptide antigen via MHC class I	GO:0042590
Regulation of apoptotic process	GO:0042981
Small molecule metabolic process	GO:0044281
Interspecies interaction between organisms	GO:0044419
Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	GO:0051436
Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	GO:0051437
Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	GO:0051439
Proteolysis involved in cellular protein catabolic process	GO:0051603

Publications from PubMed Top Help

Type 1 Diabetes Publications: 1

Publications: 93

Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR
J Biol Chem. 2011
PubMed ID: 21987572
Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.
Jiang W, Wang S, Xiao M, Lin Y, Zhou L, Lei Q, Xiong Y, Guan KL, Zhao S
Mol Cell. 2011
PubMed ID: 21726808
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Characterization of potential S-nitrosylation sites in the myocardium.
Kohr MJ, Aponte AM, Sun J, Wang G, Murphy E, Gucek M, Steenbergen C
Am J Physiol Heart Circ Physiol. 2011
PubMed ID: 21278135
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.
Keutgens A, Zhang X, Shostak K, Robert I, Olivier S, Vanderplasschen A, Chapelle JP, Viatour P, Merville MP, Bex F, Gothot A, Chariot A
J Biol Chem. 2010
PubMed ID: 20558726
PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.
Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S
Mol Cell Biol. 2010
PubMed ID: 20498273
Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes.
Ikeda Y, Demartino GN, Brown MS, Lee JN, Goldstein JL, Ye J
J Biol Chem. 2009
PubMed ID: 19815544
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW
Cell. 2009
PubMed ID: 19596235
[Influence of As(2)O(3) on proteasome beta(1)-subunit in NB4 cells].
Lü XH, Chen Y, Zhang M, He PC, Wang HY, Ni ZF, Lu R
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009
PubMed ID: 19549367
A mouse speciation gene encodes a meiotic histone H3 methyltransferase.
Mihola O, Trachtulec Z, Vlcek C, Schimenti JC, Forejt J
Science. 2009
PubMed ID: 19074312
Human protein factory for converting the transcriptome into an in vitro-expressed proteome,.
Goshima N, Kawamura Y, Fukumoto A, Miura A, Honma R, Satoh R, Wakamatsu A, Yamamoto J, Kimura K, Nishikawa T, Andoh T, Iida Y, Ishikawa K, Ito E, Kagawa N, Kaminaga C, Kanehori K, Kawakami B, Kenmochi K, Kimura R, Kobayashi M, Kuroita T, Kuwayama H, Maruyama Y, Matsuo K, Minami K, Mitsubori M, Mori M, Morishita R, Murase A, Nishikawa A, Nishikawa S, Okamoto T, Sakagami N, Sakamoto Y, Sasaki Y, Seki T, Sono S, Sugiyama A, Sumiya T, Takayama T, Takayama Y, Takeda H, Togashi T, Yahata K, Yamada H, Yanagisawa Y, Endo Y, Imamoto F, Kisu Y, Tanaka S, Isogai T, Imai J, Watanabe S, Nomura N
Nat Methods. 2008
PubMed ID: 19054851
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
Fine haplotype structure of a chromosome 17 region in the laboratory and wild mouse.
Trachtulec Z, Vlcek C, Mihola O, Gregorova S, Fotopulosova V, Forejt J
Genetics. 2008
PubMed ID: 18245833
Toward a confocal subcellular atlas of the human proteome.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Mol Cell Proteomics. 2008
PubMed ID: 18029348
Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
Ballif BA, Carey GR, Sunyaev SR, Gygi SP
J Proteome Res. 2008
PubMed ID: 18034455
EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W
Brief Funct Genomic Proteomic. 2007
PubMed ID: 17967808
Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
Wang X, Chen CF, Baker PR, Chen PL, Kaiser P, Huang L
Biochemistry. 2007
PubMed ID: 17323924
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Koch HB, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates JR, Menssen A, Hermeking H
Cell Cycle. 2007
PubMed ID: 17314511
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Large-scale analysis of the human ubiquitin-related proteome.
Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T, Nakayama KI
Proteomics. 2005
PubMed ID: 16196087
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
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Science. 2005
PubMed ID: 16141072
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S
Genome Res. 2004
PubMed ID: 15342556
A protein interaction framework for human mRNA degradation.
Lehner B, Sanderson CM
Genome Res. 2004
PubMed ID: 15231747
Mammalian Cdh1/Fzr mediates its own degradation.
Listovsky T, Oren YS, Yudkovsky Y, Mahbubani HM, Weiss AM, Lebendiker M, Brandeis M
EMBO J. 2004
PubMed ID: 15029244
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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Nature. 2004
PubMed ID: 15057822
Protein-protein interactions among human 20S proteasome subunits and proteassemblin.
Jayarapu K, Griffin TA
Biochem Biophys Res Commun. 2004
PubMed ID: 14733938
Interaction of plasminogen activator inhibitor-2 and proteasome subunit, beta type 1.
Fan J, Zhang YQ, Li P, Hou M, Tan L, Wang X, Zhu YS
Acta Biochim Biophys Sin (Shanghai). 2004
PubMed ID: 14732874
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G.
Conticello SG, Harris RS, Neuberger MS
Curr Biol. 2003
PubMed ID: 14614829
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.
Yu X, Yu Y, Liu B, Luo K, Kong W, Mao P, Yu XF
Science. 2003
PubMed ID: 14564014
The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.
Shindo K, Takaori-Kondo A, Kobayashi M, Abudu A, Fukunaga K, Uchiyama T
J Biol Chem. 2003
PubMed ID: 12970355
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.
Kao S, Khan MA, Miyagi E, Plishka R, Buckler-White A, Strebel K
J Virol. 2003
PubMed ID: 14557625
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation.
Marin M, Rose KM, Kozak SL, Kabat D
Nat Med. 2003
PubMed ID: 14528301
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif.
Sheehy AM, Gaddis NC, Malim MH
Nat Med. 2003
PubMed ID: 14528300
The DNA sequence and analysis of human chromosome 6.
Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S
Nature. 2003
PubMed ID: 14574404
Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits.
Apcher GS, Heink S, Zantopf D, Kloetzel PM, Schmid HP, Mayer RJ, Krüger E
FEBS Lett. 2003
PubMed ID: 14550573
Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.
Reuter TY, Medhurst AL, Waisfisz Q, Zhi Y, Herterich S, Hoehn H, Gross HJ, Joenje H, Hoatlin ME, Mathew CG, Huber PA
Exp Cell Res. 2003
PubMed ID: 14499622
HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.
Stopak K, de Noronha C, Yonemoto W, Greene WC
Mol Cell. 2003
PubMed ID: 14527406
Virology. Weapons of mutational destruction.
KewalRamani VN, Coffin JM
Science. 2003
PubMed ID: 12920286
Death by deamination: a novel host restriction system for HIV-1.
Goff SP
Cell. 2003
PubMed ID: 12914693
Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.
Mariani R, Chen D, Schröfelbauer B, Navarro F, König R, Bollman B, Münk C, Nymark-McMahon H, Landau NR
Cell. 2003
PubMed ID: 12859895
Good to CU.
Gu Y, Sundquist WI
Nature. 2003
PubMed ID: 12840737
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Mangeat B, Turelli P, Caron G, Friedli M, Perrin L, Trono D
Nature. 2003
PubMed ID: 12808466
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA.
Zhang H, Yang B, Pomerantz RJ, Zhang C, Arunachalam SC, Gao L
Nature. 2003
PubMed ID: 12808465
DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses.
Harris RS, Sheehy AM, Craig HM, Malim MH, Neuberger MS
Nat Immunol. 2003
PubMed ID: 12830140
DNA deamination mediates innate immunity to retroviral infection.
Harris RS, Bishop KN, Sheehy AM, Craig HM, Petersen-Mahrt SK, Watt IN, Neuberger MS, Malim MH
Cell. 2003
PubMed ID: 12809610
Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.
Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK
Dev Cell. 2003
PubMed ID: 12791267
Hypermutation of HIV-1 DNA in the absence of the Vif protein.
Lecossier D, Bouchonnet F, Clavel F, Hance AJ
Science. 2003
PubMed ID: 12750511
Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions.
Gaddis NC, Chertova E, Sheehy AM, Henderson LE, Malim MH
J Virol. 2003
PubMed ID: 12719574
RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.
Suzumori N, Burns KH, Yan W, Matzuk MM
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12525704
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.
Huang X, Seifert U, Salzmann U, Henklein P, Preissner R, Henke W, Sijts AJ, Kloetzel PM, Dubiel W
J Mol Biol. 2002
PubMed ID: 12419264
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein.
Sheehy AM, Gaddis NC, Choi JD, Malim MH
Nature. 2002
PubMed ID: 12167863
Mapping and structural dissection of human 20 S proteasome using proteomic approaches.
Claverol S, Burlet-Schiltz O, Girbal-Neuhauser E, Gairin JE, Monsarrat B
Mol Cell Proteomics. 2002
PubMed ID: 12376572
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.
Geley S, Kramer E, Gieffers C, Gannon J, Peters JM, Hunt T
J Cell Biol. 2001
PubMed ID: 11285280
Synteny of orthologous genes conserved in mammals, snake, fly, nematode, and fission yeast.
Trachtulec Z, Forejt J
Mamm Genome. 2001
PubMed ID: 11252172
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Polo-like kinase interacts with proteasomes and regulates their activity.
Feng Y, Longo DL, Ferris DK
Cell Growth Differ. 2001
PubMed ID: 11205743
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Degradation of HIV-1 integrase by the N-end rule pathway.
Mulder LC, Muesing MA
J Biol Chem. 2000
PubMed ID: 10893419
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
Transcription and RNA processing of mammalian genes in Saccharomyces cerevisiae.
Trachtulec Z, Forejt J
Nucleic Acids Res. 1999
PubMed ID: 9862975
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Evidence for a newly discovered cellular anti-HIV-1 phenotype.
Simon JH, Gaddis NC, Fouchier RA, Malim MH
Nat Med. 1998
PubMed ID: 9846577
An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein.
Madani N, Kabat D
J Virol. 1998
PubMed ID: 9811770
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S
Gene. 1997
PubMed ID: 9373149
Linkage of TATA-binding protein and proteasome subunit C5 genes in mice and humans reveals synteny conserved between mammals and invertebrates.
Trachtulec Z, Hamvas RM, Forejt J, Lehrach HR, Vincek V, Klein J
Genomics. 1997
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Isolation of candidate hybrid sterility 1 genes by cDNA selection in a 1.1 megabase pair region on mouse chromosome 17.
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Mamm Genome. 1997
PubMed ID: 9107673
HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation.
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J Biol Chem. 1997
PubMed ID: 9079628
Structure and functions of the 20S and 26S proteasomes.
Coux O, Tanaka K, Goldberg AL
Annu Rev Biochem. 1996
PubMed ID: 8811196
The genes for the alpha-type HC3 (PMSA2) and beta-type HC5 (PMSB1) subunits of human proteasomes map to chromosomes 6q27 and 7p12-p13 by fluorescence in situ hybridization.
Okumura K, Nogami M, Taguchi H, Hisamatsu H, Tanaka K
Genomics. 1995
PubMed ID: 7558012
Cloning and sequencing of a murine cDNA encoding the proteasome component C5.
Savioz A, Houghton I, Davies RW
DNA Seq. 1995
PubMed ID: 7579585
Human proteasome subunits from 2-dimensional gels identified by partial sequencing.
Kristensen P, Johnsen AH, Uerkvitz W, Tanaka K, Hendil KB
Biochem Biophys Res Commun. 1994
PubMed ID: 7811265
Isolation and characterization of alpha-type HC3 and beta-type HC5 subunit genes of human proteasomes.
Tamura T, Osaka F, Kawamura Y, Higuti T, Ishida N, Nothwang HG, Tsurumi C, Tanaka K, Ichihara A
J Mol Biol. 1994
PubMed ID: 7966316
Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.
Früh K, Gossen M, Wang K, Bujard H, Peterson PA, Yang Y
EMBO J. 1994
PubMed ID: 8045254
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
Maruyama K, Sugano S
Gene. 1994
PubMed ID: 8125298
Molecular cloning and sequence analysis of cDNAs for five major subunits of human proteasomes (multi-catalytic proteinase complexes).
Tamura T, Lee DH, Osaka F, Fujiwara T, Shin S, Chung CH, Tanaka K, Ichihara A
Biochim Biophys Acta. 1991
PubMed ID: 2025653
cDNA cloning and sequencing of component C5 of proteasomes from rat hepatoma cells.
Tamura T, Tanaka K, Kumatori A, Yamada F, Tsurumi C, Fujiwara T, Ichihara A, Tokunaga F, Aruga R, Iwanaga S
FEBS Lett. 1990
PubMed ID: 2338147
The NH2-terminal residues of rat liver proteasome (multicatalytic proteinase complex) subunits, C2, C3 and C8, are N alpha-acetylated.
Tokunaga F, Aruga R, Iwanaga S, Tanaka K, Ichihara A, Takao T, Shimonishi Y
FEBS Lett. 1990
PubMed ID: 2335242
Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome).
Lee LW, Moomaw CR, Orth K, McGuire MJ, DeMartino GN, Slaughter CA
Biochim Biophys Acta. 1990
PubMed ID: 2306472

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	5689	19170	94198
EnsEMBL Gene(s)	ENSG00000008018	ENSMUSG00000014769	ENSRNOG00000001488
Unigene	Hs.352768	Mm.32912	Rn.6016
Homologene	PSMB1	Psmb1	Psmb1
OMIM	602017	N/A	N/A
GeneCards	PSMB1	N/A	N/A
Beta Cell Genomics	DT.100884856 DT.100884860 DT.121348521 DT.454432 DT.91754030	DT.537343 DT.97400057	N/A
Reactome	P20618	N/A	N/A
Plasma Peptide Atlas	ENSP00000262193	N/A	N/A
WikiGenes	5689	19170	94198

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