B2M

Summary Top Help

Gene Description:

beta-2 microglobulin; beta-2-microglobulin

Synonyms:

Ly-m11, beta2-m, B2m, B2M, beta2m

Orthologs:

Human B2M (protein-coding), Mouse B2m (protein-coding), Rat B2m (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Mouse: 1 Rat: 1

Linkage Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd13	Mouse	chr2:114118625..158330390	44.21	582	3 no lod score

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm27	Rat	chr3:96506745..149496698	52.99	606

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr15:45003675..45011075 (7.40 kb) View in Genome Browser

(Mouse) NCBIM37 - chr2:121973422..121978819 (5.40 kb) View in Genome Browser

(Rat) RGSC3.4 - chr3:108927919..108932718 (4.80 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for B2M:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for B2M:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 1

Biocarta: 3

Reactome: 1

NCI-Nature Pathway Interaction Database: 3

Gene Ontology: 20

Publications from PubMed Top Help

Type 1 Diabetes Publications: 50

Autoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodes.
Graham KL, Krishnamurthy B, Fynch S, Mollah ZU, Slattery R, Santamaria P, Kay TW, Thomas HE
Am J Pathol. 2011
PubMed ID: 21641394
HLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/γc(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells.
Whitfield-Larry F, Young EF, Talmage G, Fudge E, Azam A, Patel S, Largay J, Byrd W, Buse J, Calikoglu AS, Shultz LD, Frelinger JA
Diabetes. 2011
PubMed ID: 21521873
Identification of Cd101 as a Susceptibility Gene for Novosphingobium aromaticivorans-Induced Liver Autoimmunity.
Mohammed JP, Fusakio ME, Rainbow DB, Moule C, Fraser HI, Clark J, Todd JA, Peterson LB, Savage PB, Wills-Karp M, Ridgway WM, Wicker LS, Mattner J
J Immunol. 2011
PubMed ID: 21613619
Incidental CD8 T cell reactivity against caspase-cleaved apoptotic self-antigens from ubiquitously expressed proteins in islets from prediabetic human leucocyte antigen-A2 transgenic non-obese diabetic mice.
Coppieters KT, Amirian N, von Herrath MG
Clin Exp Immunol. 2011
PubMed ID: 21605113
Prevention of "Humanized" Diabetogenic CD8 T-cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach.
Niens M, Grier AE, Marron M, Kay TW, Greiner DL, Serreze DV
Diabetes. 2011
PubMed ID: 21346176
Ins2 Deficiency Augments Spontaneous HLA-A*0201-Restricted T Cell Responses to Insulin.
Jarchum I, Dilorenzo TP
J Immunol. 2009
PubMed ID: 19966211
Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice.
Wu X, Wang L, Schroer S, Choi D, Chen P, Okada H, Woo M
Diabetologia. 2009
PubMed ID: 19644667
Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice.
Creusot RJ, Yaghoubi SS, Kodama K, Dang DN, Dang VH, Breckpot K, Thielemans K, Gambhir SS, Fathman CG
Clin Immunol. 2008
PubMed ID: 18337172
Targeting of pancreatic glia in type 1 diabetes.
Tsui H, Chan Y, Tang L, Winer S, Cheung RK, Paltser G, Selvanantham T, Elford AR, Ellis JR, Becker DJ, Ohashi PS, Dosch HM
Diabetes. 2008
PubMed ID: 18198358
Mechanisms of PDL1-mediated regulation of autoimmune diabetes.
Guleria I, Gubbels Bupp M, Dada S, Fife B, Tang Q, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P, Yagita H, Azuma M, Atkinson M, Bluestone JA, Sayegh MH
Clin Immunol. 2007
PubMed ID: 17627890
In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.
Jarchum I, Baker JC, Yamada T, Takaki T, Marron MP, Serreze DV, DiLorenzo TP
Diabetes. 2007
PubMed ID: 17620420
Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients.
Blancou P, Mallone R, Martinuzzi E, Sévère S, Pogu S, Novelli G, Bruno G, Charbonnel B, Dolz M, Chaillous L, van Endert P, Bach JM
J Immunol. 2007
PubMed ID: 17513797
"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.
Serreze DV, Marron MP, Dilorenzo TP
Ann N Y Acad Sci. 2007
PubMed ID: 17376821
Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice.
de Jersey J, Snelgrove SL, Palmer SE, Teteris SA, Mullbacher A, Miller JF, Slattery RM
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17229843
Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases.
Das G, Das J, Eynott P, Zhang Y, Bothwell AL, Van Kaer L, Shi Y
J Exp Med. 2006
PubMed ID: 17088432
Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways.
Dudek NL, Thomas HE, Mariana L, Sutherland RM, Allison J, Estella E, Angstetra E, Trapani JA, Santamaria P, Lew AM, Kay TW
Diabetes. 2006
PubMed ID: 16936188
CD4 T cells play major effector role and CD8 T cells initiating role in spontaneous autoimmune myocarditis of HLA-DQ8 transgenic IAb knockout nonobese diabetic mice.
Hayward SL, Bautista-Lopez N, Suzuki K, Atrazhev A, Dickie P, Elliott JF
J Immunol. 2006
PubMed ID: 16751419
HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.
Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV
J Immunol. 2006
PubMed ID: 16493087
Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: implications for the mechanism underlying variations in antigen presentation.
Roden MM, Brims DR, Fedorov AA, DiLorenzo TP, Almo SC, Nathenson SG
Mol Immunol. 2006
PubMed ID: 16229893
NKT cells and IFN-gamma establish the regulatory environment for the control of diabetogenic T cells in the nonobese diabetic mouse.
Cain JA, Smith JA, Ondr JK, Wang B, Katz JD
J Immunol. 2006
PubMed ID: 16424194
Diabetes resistance/susceptibility in T cells of nonobese diabetic mice conferred by MHC and MHC-linked genes.
Ueno A, Cho S, Cheng L, Wang Z, Wang B, Yang Y
J Immunol. 2005
PubMed ID: 16210629
NK cells promote islet allograft tolerance via a perforin-dependent mechanism.
Beilke JN, Kuhl NR, Van Kaer L, Gill RG
Nat Med. 2005
PubMed ID: 16155578
Preservation of beta-cell function during immune-mediated, B7-1-dependent alpha-cell destruction.
Skak K, Haase C, Michelsen BK
Eur J Immunol. 2005
PubMed ID: 16078275
Deranged early T cell development in immunodeficient strains of nonobese diabetic mice.
Yui MA, Rothenberg EV
J Immunol. 2004
PubMed ID: 15494484
Characterization of the role of major histocompatibility complex in type 1 diabetes recurrence after islet transplantation.
Young HY, Zucker P, Flavell RA, Jevnikar AM, Singh B
Transplantation. 2004
PubMed ID: 15446308
Genetic control of NKT cell numbers maps to major diabetes and lupus loci.
Esteban LM, Tsoutsman T, Jordan MA, Roach D, Poulton LD, Brooks A, Naidenko OV, Sidobre S, Godfrey DI, Baxter AG
J Immunol. 2003
PubMed ID: 12960309
Beta cell MHC class I is a late requirement for diabetes.
Hamilton-Williams EE, Palmer SE, Charlton B, Slattery RM
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12750472
Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.
Marron MP, Graser RT, Chapman HD, Serreze DV
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12361980
Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes.
Gonzalez A, Andre-Schmutz I, Carnaud C, Mathis D, Benoist C
Nat Immunol. 2001
PubMed ID: 11713466
Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice.
Hamilton-Williams EE, Serreze DV, Charlton B, Johnson EA, Marron MP, Mullbacher A, Slattery RM
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11572996
The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model.
Wen L, Chen NY, Tang J, Sherwin R, Wong FS
J Clin Invest. 2001
PubMed ID: 11285306
Alpha beta TCR+ cells are a minimal fraction of peripheral CD8+ pool in MHC class I-deficient mice.
Nesić D, Santori FR, Vukmanović S
J Immunol. 2000
PubMed ID: 10925270
Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.
Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV
J Immunol. 2000
PubMed ID: 10725754
Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.
Green EA, Wong FS, Eshima K, Mora C, Flavell RA
J Exp Med. 2000
PubMed ID: 10637268
Cutting edge: TCR alpha beta+ CD8 alpha alpha+ T cells are found in intestinal intraepithelial lymphocytes of mice that lack classical MHC class I molecules.
Gapin L, Cheroutre H, Kronenberg M
J Immunol. 1999
PubMed ID: 10510343
Development of CD8alpha/alpha and CD8alpha/beta T cells in major histocompatibility complex class I-deficient mice.
Das G, Janeway CA
J Exp Med. 1999
PubMed ID: 10499926
A mechanism for the major histocompatibility complex-linked resistance to autoimmunity.
Schmidt D, Verdaguer J, Averill N, Santamaria P
J Exp Med. 1997
PubMed ID: 9314555
Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent.
Serreze DV, Chapman HD, Varnum DS, Gerling I, Leiter EH, Shultz LD
J Immunol. 1997
PubMed ID: 9103469
RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice.
Kay TW, Parker JL, Stephens LA, Thomas HE, Allison J
J Immunol. 1996
PubMed ID: 8871671
Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location.
Hess J, Ladel C, Miko D, Kaufmann SH
J Immunol. 1996
PubMed ID: 8617956
Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during beta-cell tumorigenesis.
Christofori G, Naik P, Hanahan D
Nat Genet. 1995
PubMed ID: 7663515
Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin.
Mixter PF, Russell JQ, Durie FH, Budd RC
J Immunol. 1995
PubMed ID: 7868883
Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules.
Ohteki T, Iwamoto M, Izui S, MacDonald HR
Eur J Immunol. 1995
PubMed ID: 7531148
Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene.
Serreze DV, Prochazka M, Reifsnyder PC, Bridgett MM, Leiter EH
J Exp Med. 1994
PubMed ID: 7931087
Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection.
Ladel CH, Flesch IE, Arnoldi J, Kaufmann SH
J Immunol. 1994
PubMed ID: 7726898
beta-2 Microglobulin gene disruption prolongs murine islet allograft survival in NOD mice.
Osorio RW, Ascher NL, Melzer JS, Stock PG
Transplant Proc. 1994
PubMed ID: 8171644
Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant.
Serreze DV, Leiter EH, Christianson GJ, Greiner D, Roopenian DC
Diabetes. 1994
PubMed ID: 8314025
Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes.
Wicker LS, Leiter EH, Todd JA, Renjilian RJ, Peterson E, Fischer PA, Podolin PL, Zijlstra M, Jaenisch R, Peterson LB
Diabetes. 1994
PubMed ID: 8314024
Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice.
Katz J, Benoist C, Mathis D
Eur J Immunol. 1993
PubMed ID: 8258349
Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
Todd JA, Aitman TJ, Cornall RJ, Ghosh S, Hall JR, Hearne CM, Knight AM, Love JM, McAleer MA, Prins JB
Nature. 1991
PubMed ID: 1675432

Publications: 912

A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis.
Alli R, Nguyen P, Boyd K, Sundberg JP, Geiger TL
J Immunol. 2012
PubMed ID: 22116824
An MHC class Ib-restricted CD8+ T cell response to lymphocytic choriomeningitis virus.
Chen L, Jay DC, Fairbanks JD, He X, Jensen PE
J Immunol. 2011
PubMed ID: 22084437
Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma.
Challa-Malladi M, Lieu YK, Califano O, Holmes AB, Bhagat G, Murty VV, Dominguez-Sola D, Pasqualucci L, Dalla-Favera R
Cancer Cell. 2011
PubMed ID: 22137796
The neonatal Fc receptor (FcRn) is not required for IVIg or anti-CD44 monoclonal antibody-mediated amelioration of murine immune thrombocytopenia.
Crow AR, Suppa SJ, Chen X, Mott PJ, Lazarus AH
Blood. 2011
PubMed ID: 22001393
A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design.
Avci FY, Li X, Tsuji M, Kasper DL
Nat Med. 2011
PubMed ID: 22101769
Identification of a unique double-negative regulatory T-cell population.
Lee BO, Jones JE, Peters CJ, Whitacre D, Frelin L, Hughes J, Kim WK, Milich DR
Immunology. 2011
PubMed ID: 22044159
Immunization with apoptotic phagocytes containing Histoplasma capsulatum activates functional CD8(+) T cells to protect against histoplasmosis.
Hsieh SH, Lin JS, Huang JH, Wu SY, Chu CL, Kung JT, Wu-Hsieh BA
Infect Immun. 2011
PubMed ID: 21911464
ICOS-dependent stimulation of NKT cells by marginal zone B cells.
Zietara N, Łyszkiewicz M, Krueger A, Weiss S
Eur J Immunol. 2011
PubMed ID: 21809338
Host immunity and pathogen strain contribute to intestinal disaccharidase impairment following gut infection.
Solaymani-Mohammadi S, Singer SM
J Immunol. 2011
PubMed ID: 21873528
IFN-γ production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice.
Takeda K, Nakayama M, Sakaki M, Hayakawa Y, Imawari M, Ogasawara K, Okumura K, Smyth MJ
J Leukoc Biol. 2011
PubMed ID: 21712396
Development and function of innate polyclonal TCRalphabeta+ CD8+ thymocytes.
Rafei M, Hardy MP, Williams P, Vanegas JR, Forner KA, Dulude G, Labrecque N, Galipeau J, Perreault C
J Immunol. 2011
PubMed ID: 21844388
Structural insights into the pre-amyloid tetramer of β-2-microglobulin from covalent labeling and mass spectrometry.
Mendoza VL, Barón-Rodríguez MA, Blanco C, Vachet RW
Biochemistry. 2011
PubMed ID: 21718071
The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic J, Li LP, Kloetzel PM, Leisegang M, Uckert W, Blankenstein T
Blood. 2011
PubMed ID: 21613253
[Evaluation of beta2-microglobuline expression level in gastrointestinal tract tumors due to usefulness as a reference gene in PCR method].
Skrzycki M, Czeczot H, Barańczyk-Kuźma A, Mielczarek-Puta M, Chrzanowsaka A, Gajewska B
Pol Merkur Lekarski. 2011
PubMed ID: 21870705
Beta 2 microglobulin and the risk for cardiovascular events in patients with asymptomatic carotid atherosclerosis.
Amighi J, Hoke M, Mlekusch W, Schlager O, Exner M, Haumer M, Pernicka E, Koppensteiner R, Minar E, Rumpold H, Schillinger M, Wagner O
Stroke. 2011
PubMed ID: 21546482
Increases in urinary albumin and beta2-microglobulin are independently associated with blood pressure in the Japanese general population: the Takahata Study.
Mashima Y, Konta T, Kudo K, Takasaki S, Ichikawa K, Suzuki K, Shibata Y, Watanabe T, Kato T, Kawata S, Kubota I
Hypertens Res. 2011
PubMed ID: 21525950
Leishmania-infected macrophages are targets of NK cell-derived cytokines but not of NK cell cytotoxicity.
Prajeeth CK, Haeberlein S, Sebald H, Schleicher U, Bogdan C
Infect Immun. 2011
PubMed ID: 21518784
β2-microglobulin, a novel biomarker of peripheral arterial disease, independently predicts aortic stiffness in these patients.
Kals J, Zagura M, Serg M, Kampus P, Zilmer K, Unt E, Lieberg J, Eha J, Peetsalu A, Zilmer M
Scand J Clin Lab Invest. 2011
PubMed ID: 21314441
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens.
Dragovic SM, Hill T, Christianson GJ, Kim S, Elliott T, Scott D, Roopenian DC, Van Kaer L, Joyce S
J Immunol. 2011
PubMed ID: 21572029
Tmp21, a novel MHC-I interacting protein, preferentially binds to Β2-microglobulin-free MHC-I heavy chains.
Jun Y, Ahn K
BMB Rep. 2011
PubMed ID: 21699748
Value of β2-microglobulin in the serum of healthy subjects older than 40 years.
Matoković D, Hašpl M, Petrić P, Skorvaga S, Rajić MT
Ther Apher Dial. 2011
PubMed ID: 21624083
Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice.
Behrens EM, Canna SW, Slade K, Rao S, Kreiger PA, Paessler M, Kambayashi T, Koretzky GA
J Clin Invest. 2011
PubMed ID: 21576823
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.
Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, Leong HX, Glassford A, Caimol M, Kenkel JA, Tedder TF, McLaughlin T, Miklos DB, Dosch HM, Engleman EG
Nat Med. 2011
PubMed ID: 21499269
Urinary β-2-microglobulin as an alternative marker for fetal inflammatory response and development of bronchopulmonary dysplasia in premature infants.
Shima Y, Nishimaki S, Nakajima M, Kumasaka S, Migita M
J Perinatol. 2011
PubMed ID: 21127468
Cardiolipin binds to CD1d and stimulates CD1d-restricted γδ T cells in the normal murine repertoire.
Dieudé M, Striegl H, Tyznik AJ, Wang J, Behar SM, Piccirillo CA, Levine JS, Zajonc DM, Rauch J
J Immunol. 2011
PubMed ID: 21389252
Transcription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytes.
Albu DI, VanValkenburgh J, Morin N, Califano D, Jenkins NA, Copeland NG, Liu P, Avram D
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21444811
MHCI negatively regulates synapse density during the establishment of cortical connections.
Glynn MW, Elmer BM, Garay PA, Liu XB, Needleman LA, El-Sabeawy F, McAllister AK
Nat Neurosci. 2011
PubMed ID: 21358642
Cellular immune activation markers neopterin and β2-microglobulin are not elevated in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Stoeck K, Zerr I
J Neuroimmunol. 2011
PubMed ID: 21232804
Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells.
Ma G, Pan PY, Eisenstein S, Divino CM, Lowell CA, Takai T, Chen SH
Immunity. 2011
PubMed ID: 21376641
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.
Wun KS, Cameron G, Patel O, Pang SS, Pellicci DG, Sullivan LC, Keshipeddy S, Young MH, Uldrich AP, Thakur MS, Richardson SK, Howell AR, Illarionov PA, Brooks AG, Besra GS, McCluskey J, Gapin L, Porcelli SA, Godfrey DI, Rossjohn J
Immunity. 2011
PubMed ID: 21376639
Inhibition of beta2-microglobulin amyloid fibril formation by alpha2-macroglobulin.
Ozawa D, Hasegawa K, Lee YH, Sakurai K, Yanagi K, Ookoshi T, Goto Y, Naiki H
J Biol Chem. 2011
PubMed ID: 21216953
Urinary epidermal growth factor, monocyte chemotactic protein-1, and β2-microglobulin in children with ureteropelvic junction obstruction.
Bartoli F, Penza R, Aceto G, Niglio F, D'Addato O, Pastore V, Campanella V, Magaldi S, Lasalandra C, Di Bitonto G, Gesualdo L
J Pediatr Surg. 2011
PubMed ID: 21376205
Beta2-microglobulin causes abnormal phosphatidylserine exposure in human red blood cells.
Pavone B, Bucci S, Sirolli V, Merlini G, Del Boccio P, Di Rienzo M, Felaco P, Amoroso L, Sacchetta P, Di Ilio C, Federici G, Urbani A, Bonomini M
Mol Biosyst. 2011
PubMed ID: 21107472
Different prognostic factors for survival in acute and lymphomatous adult T-cell leukemia/lymphoma.
Beltran B, Quiñones P, Morales D, Cotrina E, Castillo JJ
Leuk Res. 2011
PubMed ID: 20828817
Basal and antigen-induced exposure of the proline-rich sequence in CD3ε.
de la Cruz J, Kruger T, Parks CA, Silge RL, van Oers NS, Luescher IF, Schrum AG, Gil D
J Immunol. 2011
PubMed ID: 21228347
Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts.
Fortner KA, Lees RK, MacDonald HR, Budd RC
Int Immunol. 2011
PubMed ID: 21266499
Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumors.
Maleno I, Aptsiauri N, Cabrera T, Gallego A, Paschen A, López-Nevot MA, Garrido F
Immunogenetics. 2011
PubMed ID: 21086121
Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic beta2-microglobulin variant.
Domanska K, Vanderhaegen S, Srinivasan V, Pardon E, Dupeux F, Marquez JA, Giorgetti S, Stoppini M, Wyns L, Bellotti V, Steyaert J
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21220305
Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils.
Giorgetti S, Raimondi S, Pagano K, Relini A, Bucciantini M, Corazza A, Fogolari F, Codutti L, Salmona M, Mangione P, Colombo L, De Luigi A, Porcari R, Gliozzi A, Stefani M, Esposito G, Bellotti V, Stoppini M
J Biol Chem. 2011
PubMed ID: 21068391
T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival.
Moro H, Otero DC, Tanabe Y, David M
PLoS One. 2011
PubMed ID: 21949815
Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease.
Stefanović V, Djukanović L, Cukuranović R, Bukvić D, Ležaić V, Marić I, Ogrizovic SS, Jovanović I, Vlahovic P, Pešić I, Djordjević V
Ren Fail. 2011
PubMed ID: 21332340
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
CD8+ cells enhance resistance to pulmonary serotype 3 Streptococcus pneumoniae infection in mice.
Weber SE, Tian H, Pirofski LA
J Immunol. 2011
PubMed ID: 21135172
β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.
Liu C, Sawaya MR, Eisenberg D
Nat Struct Mol Biol. 2011
PubMed ID: 21131979
Nonconventional CD8+ T cell responses to Listeria infection in mice lacking MHC class Ia and H2-M3.
Cho H, Choi HJ, Xu H, Felio K, Wang CR
J Immunol. 2011
PubMed ID: 21098224
β2-Microglobulin, pulse pressure and metabolic alterations in hemodialysis patients.
Raikou VD, Tentolouris N, Kyriaki D, Evaggelatou A, Tzanatou H
Nephron Clin Pract. 2011
PubMed ID: 20805697
MHC class I modulates NMDA receptor function and AMPA receptor trafficking.
Fourgeaud L, Davenport CM, Tyler CM, Cheng TT, Spencer MB, Boulanger LM
Proc Natl Acad Sci U S A. 2010
PubMed ID: 21135233
Cutting edge: Intrinsic programming of thymic γδT cells for specific peripheral tissue localization.
Jin Y, Xia M, Saylor CM, Narayan K, Kang J, Wiest DL, Wang Y, Xiong N
J Immunol. 2010
PubMed ID: 21068400
The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode.
Li Y, Girardi E, Wang J, Yu ED, Painter GF, Kronenberg M, Zajonc DM
J Exp Med. 2010
PubMed ID: 20921281
Effect of Ly49 haplotype variance on NK cell function and education.
Patel R, Bélanger S, Tai LH, Troke AD, Makrigiannis AP
J Immunol. 2010
PubMed ID: 20855875
Human brain weight is correlated with expression of the 'housekeeping genes' beta-2-microglobulin (β2M) and TATA-binding protein (TBP).
Harrison PJ, Laatikainen LM, Tunbridge EM, Eastwood SL
Neuropathol Appl Neurobiol. 2010
PubMed ID: 20831744
A crucial role for host APCs in the induction of donor CD4+CD25+ regulatory T cell-mediated suppression of experimental graft-versus-host disease.
Tawara I, Shlomchik WD, Jones A, Zou W, Nieves E, Liu C, Toubai T, Duran-Struuck R, Sun Y, Clouthier SG, Evers R, Lowler KP, Levy RB, Reddy P
J Immunol. 2010
PubMed ID: 20810991
Gammadelta T cells but not NK cells are essential for cell-mediated immunity against Plasmodium chabaudi malaria.
Weidanz WP, LaFleur G, Brown A, Burns JM, Gramaglia I, van der Heyde HC
Infect Immun. 2010
PubMed ID: 20660608
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.
Agerstam H, Järås M, Andersson A, Johnels P, Hansen N, Lassen C, Rissler M, Gisselsson D, Olofsson T, Richter J, Fan X, Ehinger M, Fioretos T
Blood. 2010
PubMed ID: 20554971
Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li LP, Lampert JC, Chen X, Leitao C, Popović J, Müller W, Blankenstein T
Nat Med. 2010
PubMed ID: 20693993
SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics.
Verykokakis M, Boos MD, Bendelac A, Kee BL
Immunity. 2010
PubMed ID: 20674402
Folding and fibrillogenesis: clues from beta2-microglobulin.
Rennella E, Corazza A, Giorgetti S, Fogolari F, Viglino P, Porcari R, Verga L, Stoppini M, Bellotti V, Esposito G
J Mol Biol. 2010
PubMed ID: 20558175
Magic angle spinning NMR analysis of beta2-microglobulin amyloid fibrils in two distinct morphologies.
Debelouchina GT, Platt GW, Bayro MJ, Radford SE, Griffin RG
J Am Chem Soc. 2010
PubMed ID: 20662519
IFN-alphabeta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions.
Marshall HD, Prince AL, Berg LJ, Welsh RM
J Immunol. 2010
PubMed ID: 20592282
Crystal structure of a bony fish beta2-microglobulin: insights into the evolutionary origin of immunoglobulin superfamily constant molecules.
Chen W, Gao F, Chu F, Zhang J, Gao GF, Xia C
J Biol Chem. 2010
PubMed ID: 20444690
Direct CD4 help provision following interaction of memory CD4 and CD8 T cells with distinct antigen-presenting dendritic cells.
de Goër de Herve MG, Dembele B, Vallée M, Herr F, Cariou A, Taoufik Y
J Immunol. 2010
PubMed ID: 20562265
Regulation of Th2 responses and allergic inflammation through bystander activation of CD8+ T lymphocytes in early life.
Dubois A, Deruytter N, Adams B, Kanda A, Delbauve S, Fleury S, Torres D, François A, Pétein M, Goldman M, Dombrowicz D, Flamand V
J Immunol. 2010
PubMed ID: 20562264
The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor.
Haga S, Hattori T, Sato T, Sato K, Matsuda S, Kobayakawa R, Sakano H, Yoshihara Y, Kikusui T, Touhara K
Nature. 2010
PubMed ID: 20596023
Beta-2 microglobulin levels in hemodialysis patients.
Mumtaz A, Anees M, Bilal M, Ibrahim M
Saudi J Kidney Dis Transpl. 2010
PubMed ID: 20587875
Intact NKG2D-independent function of NK cells chronically stimulated with the NKG2D ligand Rae-1.
Champsaur M, Beilke JN, Ogasawara K, Koszinowski UH, Jonjic S, Lanier LL
J Immunol. 2010
PubMed ID: 20530257
Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation.
Zavidij O, Ball CR, Herbst F, Fessler S, Schmidt M, von Kalle C, Glimm H
Blood. 2010
PubMed ID: 20382848
Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.
Tremblay M, Tremblay CS, Herblot S, Aplan PD, Hébert J, Perreault C, Hoang T
Genes Dev. 2010
PubMed ID: 20516195
Stacked sets of parallel, in-register beta-strands of beta2-microglobulin in amyloid fibrils revealed by site-directed spin labeling and chemical labeling.
Ladner CL, Chen M, Smith DP, Platt GW, Radford SE, Langen R
J Biol Chem. 2010
PubMed ID: 20335170
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.
Sakaguchi S, Hombauer M, Bilic I, Naoe Y, Schebesta A, Taniuchi I, Ellmeier W
Nat Immunol. 2010
PubMed ID: 20383150
Identification of beta2-microgloblin as a candidate for early diagnosis of imaging-invisible hepatocellular carcinoma in patient with liver cirrhosis.
Saito Y, Oba N, Nishinakagawa S, Mizuguchi Y, Kojima T, Nomura K, Nakatsura T
Oncol Rep. 2010
PubMed ID: 20372847
Elongated oligomers in beta2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry.
Smith DP, Radford SE, Ashcroft AE
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20351246
Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells.
Chong MM, Simpson N, Ciofani M, Chen G, Collins A, Littman DR
Genes Dev. 2010
PubMed ID: 20360383
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes Immun. 2010
PubMed ID: 20237496
Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.
Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, Khovananth K, Engel I, Sovath S, Lampe K, Laws E, Saunders A, Butcher GW, Kronenberg M, Steinbrecher K, Hildeman D, Grimes HL, Beutler B, Hoebe K
J Immunol. 2010
PubMed ID: 20190135
Beta 2-microglobulin can be a disease activity marker in systemic lupus erythematosus.
Kim HA, Jeon JY, Yoon JM, Suh CH
Am J Med Sci. 2010
PubMed ID: 20186038
Parenchymal cells critically curtail cytotoxic T-cell responses by inducing Bim-mediated apoptosis.
Gruber A, Cannarile MA, Cheminay C, Ried C, Marconi P, Häcker G, Brocker T
Eur J Immunol. 2010
PubMed ID: 20127674
Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.
Neves JV, Olsson IA, Porto G, Rodrigues PN
Am J Physiol Gastrointest Liver Physiol. 2010
PubMed ID: 20110460
Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin.
Heikkilä O, Susi P, Tevaluoto T, Härmä H, Marjomäki V, Hyypiä T, Kiljunen S
J Virol. 2010
PubMed ID: 20089652
The prognostic role of classical and nonclassical MHC class I expression in endometrial cancer.
Bijen CB, Bantema-Joppe EJ, de Jong RA, Leffers N, Mourits MJ, Eggink HF, van der Zee AG, Hollema H, de Bock GH, Nijman HW
Int J Cancer. 2010
PubMed ID: 19728333
Androgen receptor survival signaling is blocked by anti-beta2-microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells.
Huang WC, Zhau HE, Chung LW
J Biol Chem. 2010
PubMed ID: 20071336
T cell-dependence of Lassa fever pathogenesis.
Flatz L, Rieger T, Merkler D, Bergthaler A, Regen T, Schedensack M, Bestmann L, Verschoor A, Kreutzfeldt M, Brück W, Hanisch UK, Günther S, Pinschewer DD
PLoS Pathog. 2010
PubMed ID: 20360949
Structure of the preamyloid dimer of beta-2-microglobulin from covalent labeling and mass spectrometry.
Mendoza VL, Antwi K, Barón-Rodríguez MA, Blanco C, Vachet RW
Biochemistry. 2010
PubMed ID: 20088607
Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR.
Corazza A, Rennella E, Schanda P, Mimmi MC, Cutuil T, Raimondi S, Giorgetti S, Fogolari F, Viglino P, Frydman L, Gal M, Bellotti V, Brutscher B, Esposito G
J Biol Chem. 2010
PubMed ID: 20028983
IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections.
Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M
J Immunol. 2010
PubMed ID: 20083652
Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells.
Alvarez Arias DA, McCarty N, Lu L, Maldonado RA, Shinohara ML, Cantor H
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20133794
Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice.
Ohmura K, Ishimori N, Ohmura Y, Tokuhara S, Nozawa A, Horii S, Andoh Y, Fujii S, Iwabuchi K, Onoé K, Tsutsui H
Arterioscler Thromb Vasc Biol. 2010
PubMed ID: 19910631
Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells.
Nitta T, Murata S, Sasaki K, Fujii H, Ripen AM, Ishimaru N, Koyasu S, Tanaka K, Takahama Y
Immunity. 2010
PubMed ID: 20045355
Neurons preferentially respond to self-MHC class I allele products regardless of peptide presented.
Escande-Beillard N, Washburn L, Zekzer D, Wu ZP, Eitan S, Ivkovic S, Lu Y, Dang H, Middleton B, Bilousova TV, Yoshimura Y, Evans CJ, Joyce S, Tian J, Kaufman DL
J Immunol. 2010
PubMed ID: 20018625
Aire's partners in the molecular control of immunological tolerance.
Abramson J, Giraud M, Benoist C, Mathis D
Cell. 2010
PubMed ID: 20085707
A genetic and functional relationship between T cells and cellular proliferation in the adult hippocampus.
Huang GJ, Smith AL, Gray DH, Cosgrove C, Singer BH, Edwards A, Sim S, Parent JM, Johnsen A, Mott R, Mathis D, Klenerman P, Benoist C, Flint J
PLoS Biol. 2010
PubMed ID: 21179499
CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis.
Deb C, Lafrance-Corey RG, Schmalstieg WF, Sauer BM, Wang H, German CL, Windebank AJ, Rodriguez M, Howe CL
PLoS One. 2010
PubMed ID: 20814579
Quantitative mRNA analysis of serotonin 5-HT₄ and adrenergic β₂ receptors in the mouse embryonic telencephalon.
Hernandez MC, Janušonis S
Dev Neurosci. 2010
PubMed ID: 20805681
Early growth response 2 regulates the survival of thymocytes during positive selection.
Lawson VJ, Weston K, Maurice D
Eur J Immunol. 2010
PubMed ID: 19877014
Mouse strains with point mutations in TAP1 and TAP2.
Theodoratos A, Whittle B, Enders A, Tscharke DC, Roots CM, Goodnow CC, Fahrer AM
Immunol Cell Biol. 2010
PubMed ID: 19721454
Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo.
Kamizono S, Duncan GS, Seidel MG, Morimoto A, Hamada K, Grosveld G, Akashi K, Lind EF, Haight JP, Ohashi PS, Look AT, Mak TW
J Exp Med. 2009
PubMed ID: 19995955
Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d.
Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL
J Biol Chem. 2009
PubMed ID: 19833737
Differential requirements of MHC and of DCs for endogenous proliferation of different T-cell subsets in vivo.
Do JS, Min B
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19920180
Identification of beta2-microglobulin as a potential target for ovarian cancer.
Yang HS, Li Y, Deng HX, Peng F
Cancer Biol Ther. 2009
PubMed ID: 19829086
Expression of fully assembled TCR-CD3 complex on double positive thymocytes: synergistic role for the PRS and ER retention motifs in the intra-cytoplasmic tail of CD3epsilon.
Brodeur JF, Li S, Damlaj O, Dave VP
Int Immunol. 2009
PubMed ID: 19819936
Discrepancy between serum levels of low molecular weight proteins in acute kidney injury model rats with bilateral ureteral obstruction and bilateral nephrectomy.
Tsuda H, Isaka Y, Takahara S, Horio M
Clin Exp Nephrol. 2009
PubMed ID: 19536607
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.
Munger SC, Aylor DL, Syed HA, Magwene PM, Threadgill DW, Capel B
Genes Dev. 2009
PubMed ID: 19884258
Serum soluble interleukin-2 receptor, beta2-microglobulin, lactate dehydrogenase and erythrocyte sedimentation rate in children with Hodgkin's lymphoma.
Bien E, Balcerska A
Scand J Immunol. 2009
PubMed ID: 19874554
Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction.
Thams S, Brodin P, Plantman S, Saxelin R, Kärre K, Cullheim S
J Neurosci. 2009
PubMed ID: 19864563
CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice.
Felio K, Nguyen H, Dascher CC, Choi HJ, Li S, Zimmer MI, Colmone A, Moody DB, Brenner MB, Wang CR
J Exp Med. 2009
PubMed ID: 19808251
K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis.
Mustata M, Capone R, Jang H, Arce FT, Ramachandran S, Lal R, Nussinov R
J Am Chem Soc. 2009
PubMed ID: 19824733
Copper binding to beta-2-microglobulin and its pre-amyloid oligomers.
Srikanth R, Mendoza VL, Bridgewater JD, Zhang G, Vachet RW
Biochemistry. 2009
PubMed ID: 19754160
CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens.
Nitta T, Nitta S, Lei Y, Lipp M, Takahama Y
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19805112
Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.
Sarafova SD, Van Laethem F, Adoro S, Guinter T, Sharrow SO, Feigenbaum L, Singer A
Immunity. 2009
PubMed ID: 19747858
Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling.
Kovalovsky D, Yu Y, Dose M, Emmanouilidou A, Konstantinou T, Germar K, Aghajani K, Guo Z, Mandal M, Gounari F
J Immunol. 2009
PubMed ID: 19717519
T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling.
Terauchi M, Li JY, Bedi B, Baek KH, Tawfeek H, Galley S, Gilbert L, Nanes MS, Zayzafoon M, Guldberg R, Lamar DL, Singer MA, Lane TF, Kronenberg HM, Weitzmann MN, Pacifici R
Cell Metab. 2009
PubMed ID: 19723499
Longitudinal study of beta2-microglobulin abnormalities in schizophrenia.
Chittiprol S, Venkatasubramanian G, Neelakantachar N, Reddy NA, Shetty KT, Gangadhar BN
Int Immunopharmacol. 2009
PubMed ID: 19596084
Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity.
Honda M, Wang R, Kong WP, Kanekiyo M, Akahata W, Xu L, Matsuo K, Natarajan K, Robinson H, Asher TE, Price DA, Douek DC, Margulies DH, Nabel GJ
J Immunol. 2009
PubMed ID: 19620307
Aberrant selection and function of invariant NKT cells in the absence of AP-1 transcription factor Fra-2.
Lawson VJ, Maurice D, Silk JD, Cerundolo V, Weston K
J Immunol. 2009
PubMed ID: 19620306
Themis, a T cell-specific protein important for late thymocyte development.
Lesourne R, Uehara S, Lee J, Song KD, Li L, Pinkhasov J, Zhang Y, Weng NP, Wildt KF, Wang L, Bosselut R, Love PE
Nat Immunol. 2009
PubMed ID: 19597498
CD8 T Cells in old mice contribute to the innate immune response to Mycobacterium tuberculosis via interleukin-12p70-dependent and antigen-independent production of gamma interferon.
Vesosky B, Rottinghaus EK, Davis C, Turner J
Infect Immun. 2009
PubMed ID: 19470747
Delineating the conformational elements responsible for Cu(2+)-induced oligomerization of beta-2 microglobulin.
Blaho DV, Miranker AD
Biochemistry. 2009
PubMed ID: 19518133
Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL
Clin Exp Immunol. 2009
PubMed ID: 19659776
Spondylarthritis in HLA-B27/human beta2-microglobulin-transgenic rats is not prevented by lack of CD8.
Taurog JD, Dorris ML, Satumtira N, Tran TM, Sharma R, Dressel R, van den Brandt J, Reichardt HM
Arthritis Rheum. 2009
PubMed ID: 19565478
Analysis and clinical relevance of human leukocyte antigen class I, heavy chain, and beta2-microglobulin downregulation in breast cancer.
Morabito A, Dozin B, Salvi S, Pasciucco G, Balbi G, Laurent S, Pastorino S, Carli F, Truini M, Bruzzi P, Del Mastro L, Pistillo MP
Hum Immunol. 2009
PubMed ID: 19410618
Adapter-mediated substrate selection for endoplasmic reticulum-associated degradation.
Corcoran K, Wang X, Lybarger L
J Biol Chem. 2009
PubMed ID: 19366690
Competition between intramolecular and intermolecular interactions in an amyloid-forming protein.
Routledge KE, Tartaglia GG, Platt GW, Vendruscolo M, Radford SE
J Mol Biol. 2009
PubMed ID: 19393661
The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals.
Yanaba K, Bouaziz JD, Matsushita T, Tsubata T, Tedder TF
J Immunol. 2009
PubMed ID: 19494269
Predictive value of beta2-microglobulin (beta2-m) levels in chronic lymphocytic leukemia since Binet A stages.
Gentile M, Cutrona G, Neri A, Molica S, Ferrarini M, Morabito F
Haematologica. 2009
PubMed ID: 19483161
A new function for LAT and CD8 during CD8-mediated apoptosis that is independent of TCR signal transduction.
Clarke RL, Thiemann S, Refaeli Y, Werlen G, Potter TA
Eur J Immunol. 2009
PubMed ID: 19449311
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
In situ analysis of the antigen-processing machinery in acute myeloid leukaemic blasts by tissue microarray.
Hoves S, Aigner M, Pfeiffer C, Laumer M, Obermann EC, Mackensen A
Leukemia. 2009
PubMed ID: 19148137
NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model.
Joncker NT, Fernandez NC, Treiner E, Vivier E, Raulet DH
J Immunol. 2009
PubMed ID: 19342631
A beta2-microglobulin cleavage variant fibrillates at near-physiological pH.
Corlin DB, Johnsen CK, Nissen MH, Heegaard NH
Biochem Biophys Res Commun. 2009
PubMed ID: 19232323
Class I HLA folding and antigen presentation in beta 2-microglobulin-defective Daudi cells.
Martayan A, Sibilio L, Tremante E, Monaco EL, Mulder A, Fruci D, Cova A, Rivoltini L, Giacomini P
J Immunol. 2009
PubMed ID: 19265139
Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation.
Ricagno S, Raimondi S, Giorgetti S, Bellotti V, Bolognesi M
Biochem Biophys Res Commun. 2009
PubMed ID: 19284997
Total HLA class I loss in a sarcomatoid renal carcinoma cell line caused by the coexistence of distinct mutations in the two encoding beta2-microglobulin genes.
Hsieh CH, Hsu YJ, Chang CC, Liu HC, Chuang KL, Chuang CK, Pang ST, Hasumi K, Ferrone S, Liao SK
Cancer Immunol Immunother. 2009
PubMed ID: 18704411
Plasma levels of beta(2)-microglobulin, a biomarker of peripheral arterial disease, are not affected by maximal leg exercise in patients with intermittent claudication.
Busti C, Migliacci R, Falcinelli E, Gresele P
Atherosclerosis. 2009
PubMed ID: 18674763
Selection of reference genes for quantitative real-time RT-PCR studies in mouse brain.
Boda E, Pini A, Hoxha E, Parolisi R, Tempia F
J Mol Neurosci. 2009
PubMed ID: 18607772
Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells.
Koyama M, Hashimoto D, Aoyama K, Matsuoka K, Karube K, Niiro H, Harada M, Tanimoto M, Akashi K, Teshima T
Blood. 2009
PubMed ID: 19144988
Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin.
French JD, Roark CL, Born WK, O'Brien RL
J Immunol. 2009
PubMed ID: 19201842
Uterine natural killer cells in perforin and beta(2)-microglobulin deficient mice.
Phichitrasilp T, Hondo E, Kusakabe K, Nakagawa Y, Ihara K, Wakitani S, Kiso Y
J Vet Med Sci. 2009
PubMed ID: 19262044
Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation.
Morris SC, Heidorn SM, Herbert DR, Perkins C, Hildeman DA, Khodoun MV, Finkelman FD
J Immunol. 2009
PubMed ID: 19155490
Altered production of immunoregulatory cytokines by invariant Valpha19 TCR-bearing cells dependent on the duration and intensity of TCR engagement.
Shimamura M, Huang YY, Kobayashi M, Goji H
Int Immunol. 2009
PubMed ID: 19106232
Beta2-microglobulin abnormalities in antipsychotic-naïve schizophrenia: evidence for immune pathogenesis.
Chittiprol S, Venkatasubramanian G, Neelakantachar N, Allha N, Shetty KT, Gangadhar BN
Brain Behav Immun. 2009
PubMed ID: 18801425
Knockdown of beta2-microglobulin perturbs the subcellular distribution of HFE and hepcidin.
Bhatt L, Horgan CP, McCaffrey MW
Biochem Biophys Res Commun. 2009
PubMed ID: 19059216
A comprehensive model for packing and hydration for amyloid fibrils of beta2-microglobulin.
Lee YH, Chatani E, Sasahara K, Naiki H, Goto Y
J Biol Chem. 2009
PubMed ID: 19017634
HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity.
Weiss EH, Lilienfeld BG, Müller S, Müller E, Herbach N, Kessler B, Wanke R, Schwinzer R, Seebach JD, Wolf E, Brem G
Transplantation. 2009
PubMed ID: 19136889
Destruction of amyloid fibrils of a beta2-microglobulin fragment by laser beam irradiation.
Ozawa D, Yagi H, Ban T, Kameda A, Kawakami T, Naiki H, Goto Y
J Biol Chem. 2009
PubMed ID: 19010783
Lipid-mediated presentation of MHC class II molecules guides thymocytes to the CD4 lineage.
Komaniwa S, Hayashi H, Kawamoto H, Sato SB, Ikawa T, Katsura Y, Udaka K
Eur J Immunol. 2009
PubMed ID: 19089815
Beta2-microglobulin-dependent bacterial clearance and survival during murine Klebsiella pneumoniae bacteremia.
Cogen AL, Moore TA
Infect Immun. 2009
PubMed ID: 18981251
Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator.
Van Den Broeck T, Stevenaert F, Taveirne S, Debacker V, Vangestel C, Vandekerckhove B, Taghon T, Matthys P, Plum J, Held W, Dewerchin M, Yokoyama WM, Leclercq G
Blood. 2008
PubMed ID: 18784372
DE loop mutations affect beta2-microglobulin stability and amyloid aggregation.
Ricagno S, Colombo M, de Rosa M, Sangiovanni E, Giorgetti S, Raimondi S, Bellotti V, Bolognesi M
Biochem Biophys Res Commun. 2008
PubMed ID: 18835253
Association of heart valve calcification with malnutrition-inflammation complex syndrome, beta-microglobulin, and carotid intima media thickness in patients on hemodialysis.
Ikee R, Honda K, Oka M, Maesato K, Mano T, Moriya H, Ohtake T, Kobayashi S
Ther Apher Dial. 2008
PubMed ID: 19140844
Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome.
Birnberg T, Bar-On L, Sapoznikov A, Caton ML, Cervantes-Barragán L, Makia D, Krauthgamer R, Brenner O, Ludewig B, Brockschnieder D, Riethmacher D, Reizis B, Jung S
Immunity. 2008
PubMed ID: 19062318
Cutting edge: viral infection breaks NK cell tolerance to "missing self".
Sun JC, Lanier LL
J Immunol. 2008
PubMed ID: 19017932
NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora.
Yokote H, Miyake S, Croxford JL, Oki S, Mizusawa H, Yamamura T
Am J Pathol. 2008
PubMed ID: 18974295
Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis.
Harney SM, Vilariño-Güell C, Adamopoulos IE, Sims AM, Lawrence RW, Cardon LR, Newton JL, Meisel C, Pointon JJ, Darke C, Athanasou N, Wordsworth BP, Brown MA
Rheumatology (Oxford). 2008
PubMed ID: 18835879
Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic.
Adoro S, Erman B, Sarafova SD, Van Laethem F, Park JH, Feigenbaum L, Singer A
J Immunol. 2008
PubMed ID: 18981117
Adaptable TCR avidity thresholds for negative selection.
Stojakovic M, Salazar-Fontana LI, Tatari-Calderone Z, Badovinac VP, Santori FR, Kovalovsky D, Sant'Angelo D, Harty JT, Vukmanovic S
J Immunol. 2008
PubMed ID: 18981094
Overexpression of beta2-microglobulin is associated with poor survival in patients with oral cavity squamous cell carcinoma and contributes to oral cancer cell migration and invasion.
Chen CH, Su CY, Chien CY, Huang CC, Chuang HC, Fang FM, Huang HY, Chen CM, Chiou SJ
Br J Cancer. 2008
PubMed ID: 18841160
SIT and TRIM determine T cell fate in the thymus.
Koelsch U, Schraven B, Simeoni L
J Immunol. 2008
PubMed ID: 18941181
Kinetic coupling of folding and prolyl isomerization of beta2-microglobulin studied by mutational analysis.
Sakata M, Chatani E, Kameda A, Sakurai K, Naiki H, Goto Y
J Mol Biol. 2008
PubMed ID: 18708068
Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta 2-microglobulin-deficient mice.
Koh YI, Kim HY, Meyer EH, Pichavant M, Akbari O, Yasumi T, Savage PB, Dekruyff RH, Umetsu DT
J Immunol. 2008
PubMed ID: 18802058
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate.
Muroi S, Naoe Y, Miyamoto C, Akiyama K, Ikawa T, Masuda K, Kawamoto H, Taniuchi I
Nat Immunol. 2008
PubMed ID: 18776907
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage.
Egawa T, Littman DR
Nat Immunol. 2008
PubMed ID: 18776905
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells.
Wang L, Wildt KF, Zhu J, Zhang X, Feigenbaum L, Tessarollo L, Paul WE, Fowlkes BJ, Bosselut R
Nat Immunol. 2008
PubMed ID: 18776904
DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance.
Chaise C, Buchan SL, Rice J, Marquet J, Rouard H, Kuentz M, Vittes GE, Molinier-Frenkel V, Farcet JP, Stauss HJ, Delfau-Larue MH, Stevenson FK
Blood. 2008
PubMed ID: 18502835
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.
Hikosaka Y, Nitta T, Ohigashi I, Yano K, Ishimaru N, Hayashi Y, Matsumoto M, Matsuo K, Penninger JM, Takayanagi H, Yokota Y, Yamada H, Yoshikai Y, Inoue J, Akiyama T, Takahama Y
Immunity. 2008
PubMed ID: 18799150
Beta2-microglobulin signaling blockade inhibited androgen receptor axis and caused apoptosis in human prostate cancer cells.
Huang WC, Havel JJ, Zhau HE, Qian WP, Lue HW, Chu CY, Nomura T, Chung LW
Clin Cancer Res. 2008
PubMed ID: 18765525
Role of conformational change in the C-terminus of beta2-microglobulin in dialysis-related amyloidosis.
Kim J, Motomiya Y, Ueda M, Nakamura M, Misumi Y, Saito S, Ikemizu S, Misumi S, Ota K, Shinriki S, Kai H, Ando Y
Ann Clin Biochem. 2008
PubMed ID: 18753422
The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer.
Blum C, Graham A, Yousefzadeh M, Shrout J, Benjamin K, Krishna M, Hoda R, Hoda R, Cole DJ, Garrett-Mayer E, Reed C, Wallace M, Mitas M
Int J Oncol. 2008
PubMed ID: 18695889
Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways.
Wang J, Yuan Y, Zhou Y, Guo L, Zhang L, Kuai X, Deng B, Pan Z, Li D, He F
J Proteome Res. 2008
PubMed ID: 18624398
Defective MHC class I antigen surface expression promotes cellular survival through elevated ER stress and modulation of p53 function.
Sabapathy K, Nam SY
Cell Death Differ. 2008
PubMed ID: 18511935
Continuous engagement of a self-specific activation receptor induces NK cell tolerance.
Tripathy SK, Keyel PA, Yang L, Pingel JT, Cheng TP, Schneeberger A, Yokoyama WM
J Exp Med. 2008
PubMed ID: 18606857
CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production.
Wong KL, Lew FC, MacAry PA, Kemeny DM
Eur J Immunol. 2008
PubMed ID: 18600823
Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease.
Mizuta I, Tsunoda T, Satake W, Nakabayashi Y, Watanabe M, Takeda A, Hasegawa K, Nakashima K, Yamamoto M, Hattori N, Murata M, Toda T
Hum Genet. 2008
PubMed ID: 18568448
Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury.
Liebler JM, Lutzko C, Banfalvi A, Senadheera D, Aghamohammadi N, Crandall ED, Borok Z
Am J Physiol Lung Cell Mol Physiol. 2008
PubMed ID: 18515407
Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice.
Feng N, Kim B, Fenaux M, Nguyen H, Vo P, Omary MB, Greenberg HB
J Virol. 2008
PubMed ID: 18495762
Costimulatory effects of IL-1 on the expansion/differentiation of CD4+CD25+Foxp3+ and CD4+CD25+Foxp3- T cells.
Brinster C, Shevach EM
J Leukoc Biol. 2008
PubMed ID: 18477692
Prognostic values of serum cystatin C and beta2 microglobulin, urinary beta2 microglobulin and N-acetyl-beta-D-glucosaminidase in early acute renal failure after liver transplantation.
Hei ZQ, Li XY, Shen N, Pang HY, Zhou SL, Guan JQ
Chin Med J (Engl). 2008
PubMed ID: 18713542
CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells.
Rifa'i M, Shi Z, Zhang SY, Lee YH, Shiku H, Isobe K, Suzuki H
Int Immunol. 2008
PubMed ID: 18495626
Normal adult climbing fiber monoinnervation of cerebellar Purkinje cells in mice lacking MHC class I molecules.
Letellier M, Willson ML, Gautheron V, Mariani J, Lohof AM
Dev Neurobiol. 2008
PubMed ID: 18418877
A common beta-sheet architecture underlies in vitro and in vivo beta2-microglobulin amyloid fibrils.
Jahn TR, Tennent GA, Radford SE
J Biol Chem. 2008
PubMed ID: 18424782
beta(2)microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients.
Shrout J, Yousefzadeh M, Dodd A, Kirven K, Blum C, Graham A, Benjamin K, Hoda R, Krishna M, Romano M, Wallace M, Garrett-Mayer E, Mitas M
Br J Cancer. 2008
PubMed ID: 18506145
IL-15 expands unconventional CD8alphaalphaNK1.1+ T cells but not Valpha14Jalpha18+ NKT cells.
Terabe M, Tagaya Y, Zhu Q, Granger L, Roederer M, Waldmann TA, Berzofsky JA
J Immunol. 2008
PubMed ID: 18490727
IL-15 inhibits pre-B cell proliferation by selectively expanding Mac-1+B220+ NK cells.
Nakajima S, Hida S, Taki S
Biochem Biophys Res Commun. 2008
PubMed ID: 18339305
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties.
Esposito G, Ricagno S, Corazza A, Rennella E, Gümral D, Mimmi MC, Betto E, Pucillo CE, Fogolari F, Viglino P, Raimondi S, Giorgetti S, Bolognesi B, Merlini G, Stoppini M, Bolognesi M, Bellotti V
J Mol Biol. 2008
PubMed ID: 18395224
Beta 2-microglobulin deficient mice catabolize IgG more rapidly than FcRn- alpha-chain deficient mice.
Kim J, Bronson CL, Wani MA, Oberyszyn TM, Mohanty S, Chaudhury C, Hayton WL, Robinson JM, Anderson CL
Exp Biol Med (Maywood). 2008
PubMed ID: 18375831
Importance of CD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells.
Shi Z, Rifa'i M, Lee YH, Shiku H, Isobe K, Suzuki H
Immunology. 2008
PubMed ID: 18205792
Do beta2 microglobulin levels affect survival of newly diagnosed myeloma patients with translocation t(4;14) or 17p13 deletion treated with conventional chemotherapy?
Chng WJ, Jacobus S, Fonseca R
Leukemia. 2008
PubMed ID: 18046451
Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation.
Platt GW, Routledge KE, Homans SW, Radford SE
J Mol Biol. 2008
PubMed ID: 18342332
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy.
Guerra N, Tan YX, Joncker NT, Choy A, Gallardo F, Xiong N, Knoblaugh S, Cado D, Greenberg NR, Raulet DH
Immunity. 2008
PubMed ID: 18394936
Role of environmental and genetic factor interaction in age-related disease development: the gastric cancer paradigm.
Forte GI, Calà C, Scola L, Crivello A, Gullo A, Marasà L, Giacalone A, Bonura C, Caruso C, Lio D, Giammanco A
Rejuvenation Res. 2008
PubMed ID: 18393655
Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model.
Lukens JR, Cruise MW, Lassen MG, Hahn YS
J Immunol. 2008
PubMed ID: 18354211
TRAIL deficiency does not rescue impaired CD8+ T cell memory generated in the absence of CD4+ T cell help.
Sacks JA, Bevan MJ
J Immunol. 2008
PubMed ID: 18354179
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
White AJ, Withers DR, Parnell SM, Scott HS, Finke D, Lane PJ, Jenkinson EJ, Anderson G
Eur J Immunol. 2008
PubMed ID: 18350550
CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require direct leukemic contact to mediate GVL.
Matte-Martone C, Liu J, Jain D, McNiff J, Shlomchik WD
Blood. 2008
PubMed ID: 18223170
Procollagen C-proteinase enhancer-1 (PCPE-1) interacts with beta2-microglobulin (beta2-m) and may help initiate beta2-m amyloid fibril formation in connective tissues.
Morimoto H, Wada J, Font B, Mott JD, Hulmes DJ, Ookoshi T, Naiki H, Yasuhara A, Nakatsuka A, Fukuoka K, Takatori Y, Ichikawa H, Akagi S, Nakao K, Makino H
Matrix Biol. 2008
PubMed ID: 18164932
CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.
He X, Park K, Wang H, He X, Zhang Y, Hua X, Li Y, Kappes DJ
Immunity. 2008
PubMed ID: 18342007
Antigen-Specific CD4+ T Cells Produce Sufficient IFN-{gamma} to Mediate Robust Protective Immunity against Genital Chlamydia muridarum Infection.
Li W, Murthy AK, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP
J Immunol. 2008
PubMed ID: 18292563
Regulation of the NK cell alloreactivity to bone marrow cells by the combination of the host NK gene complex and MHC haplotypes.
Iizuka K, Scalzo AA, Xian H, Yokoyama WM
J Immunol. 2008
PubMed ID: 18292550
Polyclonal MHC Ib-Restricted CD8+ T Cells Undergo Homeostatic Expansion in the Absence of Conventional MHC-Restricted T Cells.
Jay DC, Reed-Loisel LM, Jensen PE
J Immunol. 2008
PubMed ID: 18292501
Class II-restricted protective immunity induced by malaria sporozoites.
Oliveira GA, Kumar KA, Calvo-Calle JM, Othoro C, Altszuler D, Nussenzweig V, Nardin EH
Infect Immun. 2008
PubMed ID: 18160479
Toward a confocal subcellular atlas of the human proteome.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Mol Cell Proteomics. 2008
PubMed ID: 18029348
Beta2-microglobulin amyloid fragment organization and morphology and its comparison to Abeta suggests that amyloid aggregation pathways are sequence specific.
Zheng J, Jang H, Nussinov R
Biochemistry. 2008
PubMed ID: 18215070
Amyloid nucleation triggered by agitation of beta2-microglobulin under acidic and neutral pH conditions.
Sasahara K, Yagi H, Sakai M, Naiki H, Goto Y
Biochemistry. 2008
PubMed ID: 18211100
Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn.
Mezo AR, McDonnell KA, Hehir CA, Low SC, Palombella VJ, Stattel JM, Kamphaus GD, Fraley C, Zhang Y, Dumont JA, Bitonti AJ
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18272495
Carpal tunnel syndrome and plasma beta2-microglobulin concentration in hemodialysis patients.
Shin J, Nishioka M, Shinko S, Shibuya K, Sugiki M, Kasumoto H, Fudo A, Bito Y, Fujita Y, Komaba K
Ther Apher Dial. 2008
PubMed ID: 18257814
The prognostic significance of serum beta2 microglobulin levels in acute myeloid leukemia and prognostic scores predicting survival: analysis of 1,180 patients.
Tsimberidou AM, Kantarjian HM, Wen S, O'Brien S, Cortes J, Wierda WG, Koller C, Pierce S, Brandt M, Freireich EJ, Keating MJ, Estey EH
Clin Cancer Res. 2008
PubMed ID: 18245532
Replication of beta- and gammaretroviruses is restricted in I/LnJ mice via the same genetic mechanism.
Case LK, Petell L, Yurkovetskiy L, Purdy A, Savage KJ, Golovkina TV
J Virol. 2008
PubMed ID: 18057254
Serum and tissue beta-2 microglobulin levels in patients with Helicobacter pylori infection.
Akay H, Akay A, Köklü S
Dig Dis Sci. 2008
PubMed ID: 17597407
Development of all CD4 T lineages requires nuclear factor TOX.
Aliahmad P, Kaye J
J Exp Med. 2008
PubMed ID: 18195075
Murine gammaherpesvirus 68 genes both induce and suppress lymphoproliferative disease.
Tarakanova VL, Kreisel F, White DW, Virgin HW
J Virol. 2008
PubMed ID: 17977975
Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression.
Hayakawa Y, Watt SV, Takeda K, Smyth MJ
J Leukoc Biol. 2008
PubMed ID: 17940219
A Stat5b transgene is capable of inducing CD8+ lymphoblastic lymphoma in the absence of normal TCR/MHC signaling.
Bessette K, Lang ML, Fava RA, Grundy M, Heinen J, Horne L, Spolski R, Al-Shami A, Morse HC, Leonard WJ, Kelly JA
Blood. 2008
PubMed ID: 17890450
Activation of tumor-specific CD8+ T Cells after intratumoral Ad5-TRAIL/CpG oligodeoxynucleotide combination therapy.
VanOosten RL, Griffith TS
Cancer Res. 2007
PubMed ID: 18089829
N-terminal trimer extension of nominal CD8 T cell epitopes is sufficient to promote cross-presentation to cognate CD8 T cells in vivo.
Wei CH, Sherman LA
J Immunol. 2007
PubMed ID: 18056372
Identification of protein pheromones that promote aggressive behaviour.
Chamero P, Marton TF, Logan DW, Flanagan K, Cruz JR, Saghatelian A, Cravatt BF, Stowers L
Nature. 2007
PubMed ID: 18064011
[Prognostic significance of lactate dehydrogenase and beta2-microglobulin in chronic lymphocytic leukemia]
Shen QD, Xu W, Yu H, Li L, Zhang SJ, Li JY
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007
PubMed ID: 18088490
Refolding of HLA-B27 heavy chains in the absence of beta2m yields stable high molecular weight (HMW) protein forms displaying native-like as well as non-native-like conformational features: implications for autoimmune disease.
Sharma R, Vasishta RK, Sen RK, Luthra-Guptasarma M
Biochim Biophys Acta. 2007
PubMed ID: 18036353
CCR7 expression in developing thymocytes is linked to the CD4 versus CD8 lineage decision.
Yin X, Ladi E, Chan SW, Li O, Killeen N, Kappes DJ, Robey EA
J Immunol. 2007
PubMed ID: 18025179
Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.
Takenaka K, Prasolava TK, Wang JC, Mortin-Toth SM, Khalouei S, Gan OI, Dick JE, Danska JS
Nat Immunol. 2007
PubMed ID: 17982459
Malaria protection in beta 2-microglobulin-deficient mice lacking major histocompatibility complex class I antigens: essential role of innate immunity, including gammadelta T cells.
Taniguchi T, Tachikawa S, Kanda Y, Kawamura T, Tomiyama-Miyaji C, Li C, Watanabe H, Sekikawa H, Abo T
Immunology. 2007
PubMed ID: 17916163
Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice.
Nervi B, Rettig MP, Ritchey JK, Wang HL, Bauer G, Walker J, Bonyhadi ML, Berenson RJ, Prior JL, Piwnica-Worms D, Nolta JA, DiPersio JF
Exp Hematol. 2007
PubMed ID: 17764813
Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice.
Olasz EB, Roh J, Yee CL, Arita K, Akiyama M, Shimizu H, Vogel JC, Yancey KB
J Invest Dermatol. 2007
PubMed ID: 17657247
Calcineurin sets the bandwidth for discrimination of signals during thymocyte development.
Gallo EM, Winslow MM, Canté-Barrett K, Radermacher AN, Ho L, McGinnis L, Iritani B, Neilson JR, Crabtree GR
Nature. 2007
PubMed ID: 18046413
Structure and aggregation mechanism of beta(2)-microglobulin (83-99) peptides studied by molecular dynamics simulations.
Liang C, Derreumaux P, Wei G
Biophys J. 2007
PubMed ID: 17693474
Prognostic relevance of serum beta2 microglobulin in patients with follicular lymphoma treated with anthracycline-containing regimens. A GISL study.
Federico M, Guglielmi C, Luminari S, Mammi C, Marcheselli L, Gianelli U, Maiorana A, Merli F, Bellei M, Pozzi S, Stelitano C, Lazzaro A, Gobbi PG, Baldini L, Bergantini S, Fregoni V, Brugiatelli M
Haematologica. 2007
PubMed ID: 18024396
Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.
Van Laethem F, Sarafova SD, Park JH, Tai X, Pobezinsky L, Guinter TI, Adoro S, Adams A, Sharrow SO, Feigenbaum L, Singer A
Immunity. 2007
PubMed ID: 18023370
Beta-2-microglobulin level predicts outcome following autologous hematopoietic stem cell transplantation in patients with multiple myeloma.
Stella-Holowiecka B, Czerw T, Holowiecka-Goral A, Giebel S, Wojnar J, Holowiecki J
Transplant Proc. 2007
PubMed ID: 18022010
TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production.
Goldszmid RS, Bafica A, Jankovic D, Feng CG, Caspar P, Winkler-Pickett R, Trinchieri G, Sher A
J Exp Med. 2007
PubMed ID: 17923502
Neutrophils efficiently cross-prime naive T cells in vivo.
Beauvillain C, Delneste Y, Scotet M, Peres A, Gascan H, Guermonprez P, Barnaba V, Jeannin P
Blood. 2007
PubMed ID: 17562875
Investigation into the role of macrophages in the formation and degradation of beta2-microglobulin amyloid fibrils.
Morten IJ, Gosal WS, Radford SE, Hewitt EW
J Biol Chem. 2007
PubMed ID: 17686767
Exercise-induced liver beta2-microglobulin expression is related to lower IgG clearance in the blood.
Suzuki K, Suk PJ, Hong C, Imaizumi S, Tagami K
Brain Behav Immun. 2007
PubMed ID: 17524613
Cause-specific mortality and cancer incidence rates in relation to urinary beta2-microglobulin: 23-year follow-up study in a cadmium-polluted area.
Arisawa K, Uemura H, Hiyoshi M, Dakeshita S, Kitayama A, Saito H, Soda M
Toxicol Lett. 2007
PubMed ID: 17766066
Heat-induced conversion of beta(2)-microglobulin and hen egg-white lysozyme into amyloid fibrils.
Sasahara K, Yagi H, Naiki H, Goto Y
J Mol Biol. 2007
PubMed ID: 17681531
Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction.
Joetham A, Takeda K, Miyahara N, Matsubara S, Ohnishi H, Koya T, Dakhama A, Gelfand EW
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17855564
Xenogeneic beta 2-microglobulin substitution affects functional binding of MHC class I molecules by CD8+ T cells.
Benoit LA, Tan R
J Immunol. 2007
PubMed ID: 17785793
2B4 inhibits NK-cell fratricide.
Taniguchi RT, Guzior D, Kumar V
Blood. 2007
PubMed ID: 17537992
Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination.
Kastenmuller W, Gasteiger G, Gronau JH, Baier R, Ljapoci R, Busch DH, Drexler I
J Exp Med. 2007
PubMed ID: 17709425
Presenilins regulate alphabeta T cell development by modulating TCR signaling.
Laky K, Fowlkes BJ
J Exp Med. 2007
PubMed ID: 17698590
High-resolution crystal structure of beta2-microglobulin formed at pH 7.0.
Iwata K, Matsuura T, Sakurai K, Nakagawa A, Goto Y
J Biochem. 2007
PubMed ID: 17646174
Characterization of diabetic nephropathy by urinary proteomic analysis: identification of a processed ubiquitin form as a differentially excreted protein in diabetic nephropathy patients.
Dihazi H, Müller GA, Lindner S, Meyer M, Asif AR, Oellerich M, Strutz F
Clin Chem. 2007
PubMed ID: 17634209
Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis.
Ismail N, Crossley EC, Stevenson HL, Walker DH
Infect Immun. 2007
PubMed ID: 17562770
c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3.
Maurice D, Hooper J, Lang G, Weston K
EMBO J. 2007
PubMed ID: 17641686
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.
Egawa T, Tillman RE, Naoe Y, Taniuchi I, Littman DR
J Exp Med. 2007
PubMed ID: 17646406
Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Mitaksov V, Truscott SM, Lybarger L, Connolly JM, Hansen TH, Fremont DH
Chem Biol. 2007
PubMed ID: 17719490
Xenogeneic beta 2-microglobulin substitution alters NK cell function.
Benoît LA, Tan R
J Immunol. 2007
PubMed ID: 17641012
[Relation between the level of TPS, NSE, CEA and beta2-mG in the serum and the biological behavior of small cell lung cancer].
Chen MS, Xu Y, Ma J, Wu CG, Hao XK, Lu BB, Liu T
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007
PubMed ID: 17618570
Expression of murine killer immunoglobulin-like receptor KIRL1 on CD1d-independent NK1.1(+) T cells.
Wilson EB, Parachoniak CA, Carpenito C, Mager DL, Takei F
Immunogenetics. 2007
PubMed ID: 17516061
An impaired breeding phenotype in mice with a genetic deletion of beta-2 microglobulin and diminished MHC class I expression: role in reproductive fitness.
Cooper JC, Dealtry GB, Ahmed MA, Arck PC, Klapp BF, Blois SM, Fernández N
Biol Reprod. 2007
PubMed ID: 17442853
The hereditary hemochromatosis protein HFE and its chaperone beta2-microglobulin localise predominantly to the endosomal-recycling compartment.
Bhatt L, Horgan CP, Walsh M, McCaffrey MW
Biochem Biophys Res Commun. 2007
PubMed ID: 17543888
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells.
Khan S, Bijker MS, Weterings JJ, Tanke HJ, Adema GJ, van Hall T, Drijfhout JW, Melief CJ, Overkleeft HS, van der Marel GA, Filippov DV, van der Burg SH, Ossendorp F
J Biol Chem. 2007
PubMed ID: 17462991
Beta2-microglobulin mutations in microsatellite unstable colorectal tumors.
Kloor M, Michel S, Buckowitz B, Rüschoff J, Büttner R, Holinski-Feder E, Dippold W, Wagner R, Tariverdian M, Benner A, Schwitalle Y, Kuchenbuch B, von Knebel Doeberitz M
Int J Cancer. 2007
PubMed ID: 17373663
Pathological role of osteoclast costimulation in arthritis-induced bone loss.
Ochi S, Shinohara M, Sato K, Gober HJ, Koga T, Kodama T, Takai T, Miyasaka N, Takayanagi H
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17592115
Modulation of Valpha19 NKT cell immune responses by alpha-mannosyl ceramide derivatives consisting of a series of modified sphingosines.
Shimamura M, Huang YY, Okamoto N, Suzuki N, Yasuoka J, Morita K, Nishiyama A, Amano Y, Mishina T
Eur J Immunol. 2007
PubMed ID: 17559170
Targeting beta2-microglobulin mediated signaling as a novel therapeutic approach for human renal cell carcinoma.
Nomura T, Huang WC, Seo S, Zhau HE, Mimata H, Chung LW
J Urol. 2007
PubMed ID: 17499801
An extra molecule in addition to human tapasin is required for surface expression of beta2m linked HLA-B4402 on murine cell.
Flutter B, Fu HM, Wedderburn L, Gao B
Mol Immunol. 2007
PubMed ID: 17498802
Distinct subsets of FoxP3+ regulatory T cells participate in the control of immune responses.
Stephens GL, Andersson J, Shevach EM
J Immunol. 2007
PubMed ID: 17513739
Mice lacking components of adaptive immunity show increased Brucella abortus virB mutant colonization.
Rolán HG, Tsolis RM
Infect Immun. 2007
PubMed ID: 17420243
TCR beta chain that forms peptide-independent alloreactive TCR transfers reduced reactivity with irrelevant peptide/MHC complex.
Santori FR, Popmihajlov Z, Badovinac VP, Smith C, Radoja S, Harty JT, Vukmanović S
J Immunol. 2007
PubMed ID: 17475836
Regulation of CNS synapses by neuronal MHC class I.
Goddard CA, Butts DA, Shatz CJ
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17420446
Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis.
Crozat K, Hoebe K, Ugolini S, Hong NA, Janssen E, Rutschmann S, Mudd S, Sovath S, Vivier E, Beutler B
J Exp Med. 2007
PubMed ID: 17420270
Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation.
Masuda A, Nakamura A, Maeda T, Sakamoto Y, Takai T
J Exp Med. 2007
PubMed ID: 17420263
Up-regulation of Fas (CD95) expression in tumour cells in vivo.
Peshes-Yaloz N, Rosen D, Sondel PM, Krammer PH, Berke G
Immunology. 2007
PubMed ID: 17343612
Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma cell neoplasms and late-stage differentiation of normal B cells.
Qi CF, Zhou JX, Lee CH, Naghashfar Z, Xiang S, Kovalchuk AL, Fredrickson TN, Hartley JW, Roopenian DC, Davidson WF, Janz S, Morse HC
Cancer Res. 2007
PubMed ID: 17363561
Natural regulation of immunity to minor histocompatibility antigens.
Robertson NJ, Chai JG, Millrain M, Scott D, Hashim F, Manktelow E, Lemonnier F, Simpson E, Dyson J
J Immunol. 2007
PubMed ID: 17339452
Transcriptome analysis of rat kidney cells continuously exposed to cadmium using DNA microarray.
Ohba K, Okawa Y, Matsumoto Y, Nakamura Y, Ohta H
J Toxicol Sci. 2007
PubMed ID: 17327699
Humanized mice in translational biomedical research.
Shultz LD, Ishikawa F, Greiner DL
Nat Rev Immunol. 2007
PubMed ID: 17259968
Hematopoietic progenitor cells (HPC) from mobilized peripheral blood display enhanced migration and marrow homing compared to steady-state bone marrow HPC.
Bonig H, Priestley GV, Oehler V, Papayannopoulou T
Exp Hematol. 2007
PubMed ID: 17258081
Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-alpha.
Constante M, Wang D, Raymond VA, Bilodeau M, Santos MM
Am J Pathol. 2007
PubMed ID: 17255318
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self.
Lee JW, Epardaud M, Sun J, Becker JE, Cheng AC, Yonekura AR, Heath JK, Turley SJ
Nat Immunol. 2007
PubMed ID: 17195844
Beta 2-microglobulin amyloid deposit in HLA-B27 transgenic rats.
Fukunishi S, Yoh K, Kamae S, Yoshiya S
Mod Rheumatol. 2007
PubMed ID: 17929129
Temporal changes of the plasma levels of cystatin C, beta-trace protein, beta2-microglobulin, urate and creatinine during pregnancy indicate continuous alterations in the renal filtration process.
Kristensen K, Lindström V, Schmidt C, Blirup-Jensen S, Grubb A, Wide-Swensson D, Strevens H
Scand J Clin Lab Invest. 2007
PubMed ID: 17852800
Quantitative analysis of mouse urine volatiles: in search of MHC-dependent differences.
Röck F, Hadeler KP, Rammensee HG, Overath P
PLoS ONE. 2007
PubMed ID: 17487279
Melanoma inhibiting activity protein (MIA), beta-2 microglobulin and lactate dehydrogenase (LDH) in metastatic melanoma.
Cao MG, Auge JM, Molina R, Martí R, Carrera C, Castel T, Vilella R, Conill C, Sánchez M, Malvehy J, Puig S
Anticancer Res. 2007
PubMed ID: 17348447
Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis.
Lederer CW, Torrisi A, Pantelidou M, Santama N, Cavallaro S
BMC Genomics. 2007
PubMed ID: 17244347
Ito cells are liver-resident antigen-presenting cells for activating T cell responses.
Winau F, Hegasy G, Weiskirchen R, Weber S, Cassan C, Sieling PA, Modlin RL, Liblau RS, Gressner AM, Kaufmann SH
Immunity. 2007
PubMed ID: 17239632
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling.
Daniels MA, Teixeiro E, Gill J, Hausmann B, Roubaty D, Holmberg K, Werlen G, Holländer GA, Gascoigne NR, Palmer E
Nature. 2006
PubMed ID: 17086201
Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation.
Chaudhury C, Kim J, Mehnaz S, Wani MA, Oberyszyn TM, Bronson CL, Mohanty S, Hayton WL, Robinson JM, Anderson CL
J Nutr. 2006
PubMed ID: 17116709
3D structure of amyloid protofilaments of beta2-microglobulin fragment probed by solid-state NMR.
Iwata K, Fujiwara T, Matsuki Y, Akutsu H, Takahashi S, Naiki H, Goto Y
Proc Natl Acad Sci U S A. 2006
PubMed ID: 17108084
Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.
Yu X, Bauer K, Wernhoff P, Koczan D, Möller S, Thiesen HJ, Ibrahim SM
J Immunol. 2006
PubMed ID: 17082620
FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis.
Vidarsson G, Stemerding AM, Stapleton NM, Spliethoff SE, Janssen H, Rebers FE, de Haas M, van de Winkel JG
Blood. 2006
PubMed ID: 16849638
Conformation of amyloid fibrils of beta2-microglobulin probed by tryptophan mutagenesis.
Kihara M, Chatani E, Iwata K, Yamamoto K, Matsuura T, Nakagawa A, Naiki H, Goto Y
J Biol Chem. 2006
PubMed ID: 16901902
Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins.
Huang F, Kitaura Y, Jang I, Naramura M, Kole HH, Liu L, Qin H, Schlissel MS, Gu H
Immunity. 2006
PubMed ID: 17045823
Fatal recall responses mediated by CD8 T cells during intracellular bacterial challenge infection.
Bitsaktsis C, Winslow G
J Immunol. 2006
PubMed ID: 16982903
Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation.
Savarese F, Flahndorfer K, Jaenisch R, Busslinger M, Wutz A
Mol Cell Biol. 2006
PubMed ID: 16980619
A global genomic transcriptional code associated with CNS-expressed genes.
Bailey PJ, Klos JM, Andersson E, Karlén M, Källström M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J
Exp Cell Res. 2006
PubMed ID: 16919269
PirB restricts ocular-dominance plasticity in visual cortex.
Syken J, Grandpre T, Kanold PO, Shatz CJ
Science. 2006
PubMed ID: 16917027
Structure of interacting segments in the growing amyloid fibril of beta2-microglobulin probed with IR spectroscopy.
Lu M, Hiramatsu H, Goto Y, Kitagawa T
J Mol Biol. 2006
PubMed ID: 16919295
MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression.
Kajikawa M, Baba T, Tomaru U, Watanabe Y, Koganei S, Tsuji-Kawahara S, Matsumoto N, Yamamoto K, Miyazawa M, Maenaka K, Ishizu A, Kasahara M
J Immunol. 2006
PubMed ID: 16920948
CD38 is required for the peripheral survival of immunotolerogenic CD4+ invariant NK T cells in nonobese diabetic mice.
Chen YG, Chen J, Osborne MA, Chapman HD, Besra GS, Porcelli SA, Leiter EH, Wilson SB, Serreze DV
J Immunol. 2006
PubMed ID: 16920929
Comparison of serum beta 2-microglobulin and 24 hour urinary creatinine clearance as a prognostic factor in multiple myeloma.
Yun JP, Suh C, Lee E, Chang JW, Yang WS, Park JS, Park SK
J Korean Med Sci. 2006
PubMed ID: 16891806
Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology.
Rodrigues P, Lopes C, Mascarenhas C, Arosio P, Porto G, De Sousa M
Int J Exp Pathol. 2006
PubMed ID: 16875497
Apical distribution of HFE-beta2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells.
Arredondo M, Tapia V, Rojas A, Aguirre P, Reyes F, Marzolo MP, Núñez MT
Biometals. 2006
PubMed ID: 16841247
Exothermic effects observed upon heating of beta2-microglobulin monomers in the presence of amyloid seeds.
Sasahara K, Naiki H, Goto Y
Biochemistry. 2006
PubMed ID: 16846219
Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.
Broussard C, Fleischacker C, Fleischecker C, Horai R, Chetana M, Venegas AM, Sharp LL, Hedrick SM, Fowlkes BJ, Schwartzberg PL
Immunity. 2006
PubMed ID: 16860760
Multiple polymorphic loci determine basal hepatic and splenic iron status in mice.
Grant GR, Robinson SW, Edwards RE, Clothier B, Davies R, Judah DJ, Broman KW, Smith AG
Hepatology. 2006
PubMed ID: 16799992
The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors.
Wang D, Claus CL, Vaccarelli G, Braunstein M, Schmitt TM, Zúñiga-Pflücker JC, Rothenberg EV, Anderson MK
J Immunol. 2006
PubMed ID: 16785505
Protective immunity against secondary poxvirus infection is dependent on antibody but not on CD4 or CD8 T-cell function.
Panchanathan V, Chaudhri G, Karupiah G
J Virol. 2006
PubMed ID: 16775321
Self-recognition is crucial for maintaining the peripheral CD4+ T-cell pool in a nonlymphopenic environment.
Martin B, Bécourt C, Bienvenu B, Lucas B
Blood. 2006
PubMed ID: 16527889
Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis.
Relini A, Canale C, De Stefano S, Rolandi R, Giorgetti S, Stoppini M, Rossi A, Fogolari F, Corazza A, Esposito G, Gliozzi A, Bellotti V
J Biol Chem. 2006
PubMed ID: 16601119
The coincidence of chromosome 15 aberrations and beta2-microglobulin gene mutations is causative for the total loss of human leukocyte antigen class I expression in melanoma.
Paschen A, Arens N, Sucker A, Greulich-Bode KM, Fonsatti E, Gloghini A, Striegel S, Schwinn N, Carbone A, Hildenbrand R, Cerwenka A, Maio M, Schadendorf D
Clin Cancer Res. 2006
PubMed ID: 16740750
Variants of beta-microglobulin cleaved at lysine-58 retain the main conformational features of the native protein but are more conformationally heterogeneous and unstable at physiological temperature.
Mimmi MC, Jørgensen TJ, Pettirossi F, Corazza A, Viglino P, Esposito G, De Lorenzi E, Giorgetti S, Pries M, Corlin DB, Nissen MH, Heegaard NH
FEBS J. 2006
PubMed ID: 16704420
Vaccination with human HER-2/neu (435-443) CTL peptide induces effective antitumor immunity against HER-2/neu-expressing tumor cells in vivo.
Gritzapis AD, Mahaira LG, Perez SA, Cacoullos NT, Papamichail M, Baxevanis CN
Cancer Res. 2006
PubMed ID: 16707474
Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation.
Ashour HM, Niederkorn JY
J Immunol. 2006
PubMed ID: 16670303
Mechanisms imposing the Vbeta bias of Valpha14 natural killer T cells and consequences for microbial glycolipid recognition.
Wei DG, Curran SA, Savage PB, Teyton L, Bendelac A
J Exp Med. 2006
PubMed ID: 16651387
In vitro activation of CD8 interphotoreceptor retinoid-binding protein-specific T cells requires not only antigenic stimulation but also exogenous growth factors.
Peng Y, Shao H, Ke Y, Zhang P, Xiang J, Kaplan HJ, Sun D
J Immunol. 2006
PubMed ID: 16585597
DOCK2 is required in T cell precursors for development of Valpha14 NK T cells.
Kunisaki Y, Tanaka Y, Sanui T, Inayoshi A, Noda M, Nakayama T, Harada M, Taniguchi M, Sasazuki T, Fukui Y
J Immunol. 2006
PubMed ID: 16585555
Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.
Castellino F, Huang AY, Altan-Bonnet G, Stoll S, Scheinecker C, Germain RN
Nature. 2006
PubMed ID: 16612374
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
NK cell-mediated immunopathology during an acute viral infection of the CNS.
Alsharifi M, Lobigs M, Simon MM, Kersten A, Müller K, Koskinen A, Lee E, Müllbacher A
Eur J Immunol. 2006
PubMed ID: 16541469
Down-regulation of human leukocyte antigen class I and II and beta 2-microglobulin expression in human herpesvirus-7-infected cells.
Mirandola P, Sponzilli I, Solenghi E, Micheloni C, Rinaldi L, Gobbi G, Vitale M
J Infect Dis. 2006
PubMed ID: 16518752
Analysis of the DNA sequence and duplication history of human chromosome 15.
Zody MC, Garber M, Sharpe T, Young SK, Rowen L, O'Neill K, Whittaker CA, Kamal M, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Kodira CD, Madan A, Qin S, Yang X, Abbasi N, Abouelleil A, Arachchi HM, Baradarani L, Birditt B, Bloom S, Bloom T, Borowsky ML, Burke J, Butler J, Cook A, DeArellano K, DeCaprio D, Dorris L, Dors M, Eichler EE, Engels R, Fahey J, Fleetwood P, Friedman C, Gearin G, Hall JL, Hensley G, Johnson E, Jones C, Kamat A, Kaur A, Locke DP, Madan A, Munson G, Jaffe DB, Lui A, Macdonald P, Mauceli E, Naylor JW, Nesbitt R, Nicol R, O'Leary SB, Ratcliffe A, Rounsley S, She X, Sneddon KM, Stewart S, Sougnez C, Stone SM, Topham K, Vincent D, Wang S, Zimmer AR, Birren BW, Hood L, Lander ES, Nusbaum C
Nature. 2006
PubMed ID: 16572171
Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene.
Wani MA, Haynes LD, Kim J, Bronson CL, Chaudhury C, Mohanty S, Waldmann TA, Robinson JM, Anderson CL
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16549777
Molecular dynamics simulations and free energy analyses on the dimer formation of an amyloidogenic heptapeptide from human beta2-microglobulin: implication for the protofibril structure.
Lei H, Wu C, Wang Z, Duan Y
J Mol Biol. 2006
PubMed ID: 16403526
Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.
Jahn TR, Parker MJ, Homans SW, Radford SE
Nat Struct Mol Biol. 2006
PubMed ID: 16491092
A native to amyloidogenic transition regulated by a backbone trigger.
Eakin CM, Berman AJ, Miranker AD
Nat Struct Mol Biol. 2006
PubMed ID: 16491088
A systematic study of the effect of physiological factors on beta2-microglobulin amyloid formation at neutral pH.
Myers SL, Jones S, Jahn TR, Morten IJ, Tennent GA, Hewitt EW, Radford SE
Biochemistry. 2006
PubMed ID: 16475820
Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin.
Achour A, Michaëlsson J, Harris RA, Ljunggren HG, Kärre K, Schneider G, Sandalova T
J Mol Biol. 2006
PubMed ID: 16375919
Cross-positive selection of thymocytes expressing a single TCR by multiple major histocompatibility complex molecules of both classes: implications for CD4+ versus CD8+ lineage commitment.
Eshima K, Suzuki H, Shinohara N
J Immunol. 2006
PubMed ID: 16424192
Differential effect of imipenem treatment on injury caused by cecal ligation and puncture in wild-type and NK cell-deficient beta(2)-microgloblin knockout mice.
Enoh VT, Lin CY, Varma TK, Sherwood ER
Am J Physiol Gastrointest Liver Physiol. 2006
PubMed ID: 16166341
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.
Bhattacharya D, Rossi DJ, Bryder D, Weissman IL
J Exp Med. 2006
PubMed ID: 16380511
TACI-BLyS signaling via B-cell-dendritic cell cooperation is required for naive CD8+ T-cell priming in vivo.
Diaz-de-Durana Y, Mantchev GT, Bram RJ, Franco A
Blood. 2006
PubMed ID: 16195331
Effect of tibolone on cytochrome c oxidase I, beta-2-microglobulin and vascular endothelial growth factor gene expression in the lower urinary tract of castrated rats.
Hamerski MG, Bortolini MA, Da Silva ID, Castro RA, Sartori MG, De Lima GR, Girão MJ
Clin Exp Obstet Gynecol. 2006
PubMed ID: 17211973
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.
Winau F, Weber S, Sad S, de Diego J, Hoops SL, Breiden B, Sandhoff K, Brinkmann V, Kaufmann SH, Schaible UE
Immunity. 2006
PubMed ID: 16413927
Molecular, cellular, and antigen requirements for development of age-associated T cell clonal expansions in vivo.
Messaoudi I, Warner J, Nikolich-Zugich D, Fischer M, Nikolich-Zugich J
J Immunol. 2006
PubMed ID: 16365422
Peptide-induced immune protection of CD8+ T cell-deficient mice against Friend retrovirus-induced disease.
Kawabata H, Niwa A, Tsuji-Kawahara S, Uenishi H, Iwanami N, Matsukuma H, Abe H, Tabata N, Matsumura H, Miyazawa M
Int Immunol. 2006
PubMed ID: 16352628
Simulation of pH-dependent edge strand rearrangement in human beta-2 microglobulin.
Park S, Saven JG
Protein Sci. 2006
PubMed ID: 16322574
CD8 T cell-mediated lung damage in response to the extracellular pathogen pneumocystis is dependent on MHC class I expression by radiation-resistant lung cells.
Meissner NN, Lund FE, Han S, Harmsen A
J Immunol. 2005
PubMed ID: 16339567
AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin.
Raman B, Ban T, Sakai M, Pasta SY, Ramakrishna T, Naiki H, Goto Y, Rao ChM
Biochem J. 2005
PubMed ID: 16053447
IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.
Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV
J Neurosci. 2005
PubMed ID: 16354907
Characterization of two distinct beta2-microglobulin unfolding intermediates that may lead to amyloid fibrils of different morphology.
Armen RS, Daggett V
Biochemistry. 2005
PubMed ID: 16331970
Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin.
Sandalova T, Michaëlsson J, Harris RA, Ljunggren HG, Kärre K, Schneider G, Achour A
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005
PubMed ID: 16511243
H2-M3 major histocompatibility complex class Ib-restricted CD8 T cells induced by Salmonella enterica serovar Typhimurium infection recognize proteins released by Salmonella serovar Typhimurium.
Ugrinovic S, Brooks CG, Robson J, Blacklaws BA, Hormaeche CE, Robinson JH
Infect Immun. 2005
PubMed ID: 16299293
Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice.
Tarakanova VL, Suarez F, Tibbetts SA, Jacoby MA, Weck KE, Hess JL, Speck SH, Virgin HW
J Virol. 2005
PubMed ID: 16282467
CD1d-independent developmental acquisition of prompt IL-4 gene inducibility in thymus CD161(NK1)-CD44lowCD4+CD8- T cells is associated with complementarity determining region 3-diverse and biased Vbeta2/Vbeta7/Vbeta8/Valpha3.2 T cell receptor usage.
Chen YT, Kung JT
J Immunol. 2005
PubMed ID: 16272308
CD8 T cells require gamma interferon to clear borna disease virus from the brain and prevent immune system-mediated neuronal damage.
Hausmann J, Pagenstecher A, Baur K, Richter K, Rziha HJ, Staeheli P
J Virol. 2005
PubMed ID: 16227271
{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.
French JD, Roark CL, Born WK, O'brien RL
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16203967
Cardiac troponin I and beta 2 microglobulin as risk factors for early-onset atherosclerosis in patients on haemodialysis.
Zumrutdal A, Sezer S, Demircan S, Seydaoglu G, Ozdemir FN, Haberal M
Nephrology (Carlton). 2005
PubMed ID: 16221094
Seeding-dependent propagation and maturation of amyloid fibril conformation.
Yamaguchi K, Takahashi S, Kawai T, Naiki H, Goto Y
J Mol Biol. 2005
PubMed ID: 16126222
Main-chain dominated amyloid structures demonstrated by the effect of high pressure.
Chatani E, Kato M, Kawai T, Naiki H, Goto Y
J Mol Biol. 2005
PubMed ID: 16122756
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
Kinetically controlled thermal response of beta2-microglobulin amyloid fibrils.
Sasahara K, Naiki H, Goto Y
J Mol Biol. 2005
PubMed ID: 16098535
Ultrasonication-induced amyloid fibril formation of beta2-microglobulin.
Ohhashi Y, Kihara M, Naiki H, Goto Y
J Biol Chem. 2005
PubMed ID: 16046408
Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance.
Hida S, Tadachi M, Saito T, Taki S
Blood. 2005
PubMed ID: 15914553
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.
Oppenheim DE, Roberts SJ, Clarke SL, Filler R, Lewis JM, Tigelaar RE, Girardi M, Hayday AC
Nat Immunol. 2005
PubMed ID: 16116470
Early cytokine production is associated with protection from murine cerebral malaria.
Mitchell AJ, Hansen AM, Hee L, Ball HJ, Potter SM, Walker JC, Hunt NH
Infect Immun. 2005
PubMed ID: 16113282
Multiple survival signals are delivered by dendritic cells to naive CD4+ T cells.
Feuillet V, Lucas B, Di Santo JP, Bismuth G, Trautmann A
Eur J Immunol. 2005
PubMed ID: 16078277
Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.
Gosal WS, Morten IJ, Hewitt EW, Smith DA, Thomson NH, Radford SE
J Mol Biol. 2005
PubMed ID: 16024039
Cutting edge: a single MHC class Ia is sufficient for CD8 memory T cell differentiation.
Williams MA, Bevan MJ
J Immunol. 2005
PubMed ID: 16081772
Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection.
Warfield KL, Olinger G, Deal EM, Swenson DL, Bailey M, Negley DL, Hart MK, Bavari S
J Immunol. 2005
PubMed ID: 16002721
Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway.
Chen M, Tabaczewski P, Truscott SM, Van Kaer L, Stroynowski I
J Immunol. 2005
PubMed ID: 16002705
Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling.
McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S
J Immunol. 2005
PubMed ID: 16002660
Restricted MHC-peptide repertoire predisposes to autoimmunity.
Logunova NN, Viret C, Pobezinsky LA, Miller SA, Kazansky DB, Sundberg JP, Chervonsky AV
J Exp Med. 2005
PubMed ID: 15998789
Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.
Sarafova SD, Erman B, Yu Q, Van Laethem F, Guinter T, Sharrow SO, Feigenbaum L, Wildt KF, Ellmeier W, Singer A
Immunity. 2005
PubMed ID: 16039581
Peripheral CD8+CD25+ T lymphocytes from MHC class II-deficient mice exhibit regulatory activity.
Bienvenu B, Martin B, Auffray C, Cordier C, Bécourt C, Lucas B
J Immunol. 2005
PubMed ID: 15972655
MHC class I-positive dendritic cells (DC) control CD8 T cell homeostasis in vivo: T cell lymphopenia as a prerequisite for DC-mediated homeostatic proliferation of naive CD8 T cells.
Gruber A, Brocker T
J Immunol. 2005
PubMed ID: 15972649
Beta2-microglobulin required for cell surface expression of blastocyst MHC.
Tanaka T, Ebata T, Tajima A, Kinoshita K, Okumura K, Yagita H
Biochem Biophys Res Commun. 2005
PubMed ID: 15896332
Synthetic alpha-mannosyl ceramide as a potent stimulant for an NKT cell repertoire bearing the invariant Valpha19-Jalpha26 TCR alpha chain.
Okamoto N, Kanie O, Huang YY, Fujii R, Watanabe H, Shimamura M
Chem Biol. 2005
PubMed ID: 15975513
EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses.
Linker RA, Rott E, Hofstetter HH, Hanke T, Toyka KV, Gold R
Neurobiol Dis. 2005
PubMed ID: 15837577
Dendritic cells cross-present exogenous fungal antigens to stimulate a protective CD8 T cell response in infection by Histoplasma capsulatum.
Lin JS, Yang CW, Wang DW, Wu-Hsieh BA
J Immunol. 2005
PubMed ID: 15879127
IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells.
Taki S, Nakajima S, Ichikawa E, Saito T, Hida S
J Immunol. 2005
PubMed ID: 15879093
Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.
Haks MC, Lefebvre JM, Lauritsen JP, Carleton M, Rhodes M, Miyazaki T, Kappes DJ, Wiest DL
Immunity. 2005
PubMed ID: 15894277
Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.
Toyama-Sorimachi N, Omatsu Y, Onoda A, Tsujimura Y, Iyoda T, Kikuchi-Maki A, Sorimachi H, Dohi T, Taki S, Inaba K, Karasuyama H
J Immunol. 2005
PubMed ID: 15814685
Gamma delta T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors.
Baccala R, Witherden D, Gonzalez-Quintial R, Dummer W, Surh CD, Havran WL, Theofilopoulos AN
J Immunol. 2005
PubMed ID: 15814683
Interleukin 10- and Fcgamma receptor-deficient mice resolve Leishmania mexicana lesions.
Buxbaum LU, Scott P
Infect Immun. 2005
PubMed ID: 15784551
Mechanism of hypoalbuminemia in rodents.
Koltun M, Nikolovski J, Strong K, Nikolic-Paterson D, Comper WD
Am J Physiol Heart Circ Physiol. 2005
PubMed ID: 15539420
CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization.
Malley R, Trzcinski K, Srivastava A, Thompson CM, Anderson PW, Lipsitch M
Proc Natl Acad Sci U S A. 2005
PubMed ID: 15781870
Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin.
Heegaard NH, Jørgensen TJ, Rozlosnik N, Corlin DB, Pedersen JS, Tempesta AG, Roepstorff P, Bauer R, Nissen MH
Biochemistry. 2005
PubMed ID: 15766269
Regulatory T cell lineage specification by the forkhead transcription factor foxp3.
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY
Immunity. 2005
PubMed ID: 15780990
Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes.
Sato T, Ohno S, Hayashi T, Sato C, Kohu K, Satake M, Habu S
Immunity. 2005
PubMed ID: 15780989
Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage.
Kohu K, Sato T, Ohno S, Hayashi K, Uchino R, Abe N, Nakazato M, Yoshida N, Kikuchi T, Iwakura Y, Inoue Y, Watanabe T, Habu S, Satake M
J Immunol. 2005
PubMed ID: 15728469
Interferon-gamma mediates antigen trafficking to MHC class II-positive late endosomes of enterocytes.
Büning J, Schmitz M, Repenning B, Ludwig D, Schmidt MA, Strobel S, Zimmer KP
Eur J Immunol. 2005
PubMed ID: 15688349
Molecular responses to stress induced in normal human caucasian melanocytes in culture by exposure to simulated solar UV.
Marrot L, Belaïdi JP, Jones C, Perez P, Meunier JR
Photochem Photobiol. 2005
PubMed ID: 15623356
The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.
He X, He X, Dave VP, Zhang Y, Hua X, Nicolas E, Xu W, Roe BA, Kappes DJ
Nature. 2005
PubMed ID: 15729333
Cutting edge: antibody production to pneumococcal polysaccharides requires CD1 molecules and CD8+ T cells.
Kobrynski LJ, Sousa AO, Nahmias AJ, Lee FK
J Immunol. 2005
PubMed ID: 15699104
Critical balance of electrostatic and hydrophobic interactions is required for beta 2-microglobulin amyloid fibril growth and stability.
Raman B, Chatani E, Kihara M, Ban T, Sakai M, Hasegawa K, Naiki H, Rao ChM, Goto Y
Biochemistry. 2005
PubMed ID: 15667222
Selective Rac1 inhibition in dendritic cells diminishes apoptotic cell uptake and cross-presentation in vivo.
Kerksiek KM, Niedergang F, Chavrier P, Busch DH, Brocker T
Blood. 2005
PubMed ID: 15383465
Can cystatin C be a better marker for the early detection of renal damage in primary hypertensive patients?
Ozer BA, Dursun B, Baykal A, Gultekin M, Suleymanlar G
Ren Fail. 2005
PubMed ID: 15957539
Studies on unfolded beta-microglobulin at C-terminal in dialysis-related amyloidosis.
Motomiya Y, Ando Y, Haraoka K, Sun X, Morita H, Amano I, Uchimura T, Maruyama I
Kidney Int. 2005
PubMed ID: 15610257
Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells.
Ackerman AL, Kyritsis C, Tampé R, Cresswell P
Nat Immunol. 2005
PubMed ID: 15592474
Effect of childhood obesity and obesity-related cardiovascular risk factors on glomerular and tubular protein excretion.
Csernus K, Lanyi E, Erhardt E, Molnar D
Eur J Pediatr. 2005
PubMed ID: 15517379
Direct measurement of the thermodynamic parameters of amyloid formation by isothermal titration calorimetry.
Kardos J, Yamamoto K, Hasegawa K, Naiki H, Goto Y
J Biol Chem. 2004
PubMed ID: 15494406
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division.
Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, Yaspo ML, Himmelbauer H, Korn B, Neugebauer K, Pisabarro MT, Buchholz F
Nature. 2004
PubMed ID: 15616564
A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy.
Oliveira AL, Thams S, Lidman O, Piehl F, Hökfelt T, Kärre K, Lindå H, Cullheim S
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15591351
MHC class I, beta2 microglobulin, and the INF-gamma receptor are upregulated in aged motoneurons.
Edström E, Kullberg S, Ming Y, Zheng H, Ulfhake B
J Neurosci Res. 2004
PubMed ID: 15505791
Evidence for selective transformation of autoreactive immature plasma cells in mice deficient in Fasl.
Zhang JQ, Okumura C, McCarty T, Shin MS, Mukhopadhyay P, Hori M, Torrey TA, Naghashfar Z, Zhou JX, Lee CH, Roopenian DC, Morse HC, Davidson WF
J Exp Med. 2004
PubMed ID: 15583018
HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.
Roeth JF, Williams M, Kasper MR, Filzen TM, Collins KL
J Cell Biol. 2004
PubMed ID: 15569716
Mice depleted of CD8+ T and NK cells are resistant to injury caused by cecal ligation and puncture.
Sherwood ER, Enoh VT, Murphey ED, Lin CY
Lab Invest. 2004
PubMed ID: 15448711
Exclusion and inclusion of TCR alpha proteins during T cell development in TCR-transgenic and normal mice.
Lacorazza HD, Nikolich-Zugich J
J Immunol. 2004
PubMed ID: 15494509
Conformational stability of amyloid fibrils of beta2-microglobulin probed by guanidine-hydrochloride-induced unfolding.
Narimoto T, Sakurai K, Okamoto A, Chatani E, Hoshino M, Hasegawa K, Naiki H, Goto Y
FEBS Lett. 2004
PubMed ID: 15498554
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
A nonclassical MHC class I molecule restricts CTL-mediated rejection of a syngeneic melanoma tumor.
Chiang EY, Stroynowski I
J Immunol. 2004
PubMed ID: 15383569
Analysis of the major histocompatibility complex in graft rejection revisited by gene expression profiles.
Christopher K, Liang Y, Mueller TF, DeFina R, He H, Haley KJ, Exley MA, Finn PW, Perkins DL
Transplantation. 2004
PubMed ID: 15385796
Differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to Qa-1b-restricted CTLs.
Li L, Sullivan BA, Aldrich CJ, Soloski MJ, Forman J, Grandea AG, Jensen PE, Van Kaer L
J Immunol. 2004
PubMed ID: 15356116
Evaluation of beta2 microglobulin level as a marker to determine HIV/AIDS progression.
Gupta SM, Ray K, Bala M
J Commun Dis. 2004
PubMed ID: 16509252
Molecular analysis of iron overload in beta2-microglobulin-deficient mice.
Muckenthaler MU, Rodrigues P, Macedo MG, Minana B, Brennan K, Cardoso EM, Hentze MW, de Sousa M
Blood Cells Mol Dis. 2004
PubMed ID: 15315790
The LILR family: modulators of innate and adaptive immune pathways in health and disease.
Brown D, Trowsdale J, Allen R
Tissue Antigens. 2004
PubMed ID: 15304001
Donor APCs are required for maximal GVHD but not for GVL.
Matte CC, Liu J, Cormier J, Anderson BE, Athanasiadis I, Jain D, McNiff J, Shlomchik WD
Nat Med. 2004
PubMed ID: 15286785
CCR7 signals are essential for cortex-medulla migration of developing thymocytes.
Ueno T, Saito F, Gray DH, Kuse S, Hieshima K, Nakano H, Kakiuchi T, Lipp M, Boyd RL, Takahama Y
J Exp Med. 2004
PubMed ID: 15302902
The MHC-encoded class I molecule, H-2Kk, demonstrates distinct requirements of assembly factors for cell surface expression: roles of TAP, Tapasin and beta2-microglobulin.
Prasanna SJ, Nandi D
Mol Immunol. 2004
PubMed ID: 15302165
Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE.
Frazer DM, Wilkins SJ, Millard KN, McKie AT, Vulpe CD, Anderson GJ
Br J Haematol. 2004
PubMed ID: 15257718
An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder.
Jordan MB, Hildeman D, Kappler J, Marrack P
Blood. 2004
PubMed ID: 15069016
An amyloid-forming segment of beta2-microglobulin suggests a molecular model for the fibril.
Ivanova MI, Sawaya MR, Gingery M, Attinger A, Eisenberg D
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15249659
The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes.
Lee P, Peng H, Gelbart T, Beutler E
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15192150
Defined alphabeta T cell receptors with distinct ligand specificities do not require those ligands to signal double negative thymocyte differentiation.
Erman B, Guinter TI, Singer A
J Exp Med. 2004
PubMed ID: 15210747
Development of antigen-specific CD8+ CTL in MHC class I-deficient mice through CD4 to CD8 conversion.
Tanaka Y, Koido S, Xia J, Ohana M, Liu C, Cote GM, Sawyer DB, Calderwood S, Gong J
J Immunol. 2004
PubMed ID: 15187169
Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo - role of KARAP/DAP12-dependent and -independent pathways.
Oberg L, Johansson S, Michaëlsson J, Tomasello E, Vivier E, Kärre K, Höglund P
Eur J Immunol. 2004
PubMed ID: 15162434
CD1d-independent NKT cells in beta 2-microglobulin-deficient mice have hybrid phenotype and function of NK and T cells.
Maeda M, Shadeo A, MacFadyen AM, Takei F
J Immunol. 2004
PubMed ID: 15128797
Serial beta-2 microglobulin measurement as an auxilliary method in the early diagnosis of cytomegalovirus infection in renal transplant patients.
Matos AC, Durão MS, Pacheco-Silva A
Transplant Proc. 2004
PubMed ID: 15194307
The role of beta2 microglobulin levels in monitoring chronic hepatitis B.
Yegane S, Revanli M, Taneli F
Tohoku J Exp Med. 2004
PubMed ID: 15185972
Pro-Th1 cytokines promote Fas-dependent apoptosis of immature peripheral basophils.
Schneider E, Tonanny MB, Lisbonne M, Leite-de-Moraes M, Dy M
J Immunol. 2004
PubMed ID: 15100264
Essential role of MHC II-independent CD4+ T cells, IL-4 and STAT6 in contact hypersensitivity induced by fluorescein isothiocyanate in the mouse.
Takeshita K, Yamasaki T, Akira S, Gantner F, Bacon KB
Int Immunol. 2004
PubMed ID: 15096484
Beta2-microglobulin and cystatin C in type 2 diabetes: assessment of diabetic nephropathy.
Aksun SA, Ozmen D, Ozmen B, Parildar Z, Mutaf I, Turgan N, Habif S, Kumanlioğluc K, Bayindir O
Exp Clin Endocrinol Diabetes. 2004
PubMed ID: 15127324
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome Res. 2004
PubMed ID: 15060019
Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice.
Miranda CJ, Makui H, Andrews NC, Santos MM
Blood. 2004
PubMed ID: 14656877
Innate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells.
Street SE, Hayakawa Y, Zhan Y, Lew AM, MacGregor D, Jamieson AM, Diefenbach A, Yagita H, Godfrey DI, Smyth MJ
J Exp Med. 2004
PubMed ID: 15007091
Optimum amyloid fibril formation of a peptide fragment suggests the amyloidogenic preference of beta2-microglobulin under physiological conditions.
Ohhashi Y, Hasegawa K, Naiki H, Goto Y
J Biol Chem. 2004
PubMed ID: 14699107
Beta2-microglobulin knockout mice treated with anti-asialoGM1 exhibit improved hemodynamics and cardiac contractile function during acute intra-abdominal sepsis.
Tao W, Sherwood ER
Am J Physiol Regul Integr Comp Physiol. 2004
PubMed ID: 14630624
The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells.
Tyznik AJ, Sun JC, Bevan MJ
J Exp Med. 2004
PubMed ID: 14769854
The crystal structure of human CD1b with a bound bacterial glycolipid.
Batuwangala T, Shepherd D, Gadola SD, Gibson KJ, Zaccai NR, Fersht AR, Besra GS, Cerundolo V, Jones EY
J Immunol. 2004
PubMed ID: 14764708
Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain.
Lilić M, Popmihajlov Z, Monaco JJ, Vukmanović S
Immunogenetics. 2004
PubMed ID: 14735325
beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation.
Rosano C, Zuccotti S, Mangione P, Giorgetti S, Bellotti V, Pettirossi F, Corazza A, Viglino P, Esposito G, Bolognesi M
J Mol Biol. 2004
PubMed ID: 14698299
Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus.
Li N, Nakamura K, Jiang Y, Tsurui H, Matsuoka S, Abe M, Ohtsuji M, Nishimura H, Kato K, Kawai T, Atsumi T, Koike T, Shirai T, Ueno H, Hirose S
Hum Mol Genet. 2004
PubMed ID: 14695357
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He XH, Xu LH, Liu Y, Zeng YY
Sheng Wu Gong Cheng Xue Bao. 2004
PubMed ID: 16108498
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Thymic selection and peripheral activation of CD8 T cells by the same class I MHC/peptide complex.
Mintern JD, Maurice MM, Ploegh HL, Schott E
J Immunol. 2004
PubMed ID: 14688383
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
Amyloid fibril formation in the context of full-length protein: effects of proline mutations on the amyloid fibril formation of beta2-microglobulin.
Chiba T, Hagihara Y, Higurashi T, Hasegawa K, Naiki H, Goto Y
J Biol Chem. 2003
PubMed ID: 12958308
CD8+ T lymphocytes regulating Th2 pathology escape neonatal tolerization.
Adams B, Nagy N, Paulart F, Vanderhaeghen ML, Goldman M, Flamand V
J Immunol. 2003
PubMed ID: 14607904
Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration.
Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP
J Neurosci. 2003
PubMed ID: 14586011
Beta-2 microglobulin in ESRD: an in-depth review.
Winchester JF, Salsberg JA, Levin NW
Adv Ren Replace Ther. 2003
PubMed ID: 14681859
In vivo treatment of class II MHC-deficient mice with anti-TCR antibody restores the generation of circulating CD4 T cells and optimal architecture of thymic medulla.
Nasreen M, Ueno T, Saito F, Takahama Y
J Immunol. 2003
PubMed ID: 14500633
HBsAg/HLA-A2 transgenic mice: a model for T cell tolerance to hepatitis B surface antigen in chronic hepatitis B virus infection.
Loirat D, Mancini-Bourgine M, Abastado JP, Michel ML
Int Immunol. 2003
PubMed ID: 13679383
Cutting Edge: Multiple autoimmune pathways in kd/kd mice.
Hancock WW, Tsai TL, Madaio MP, Gasser DL
J Immunol. 2003
PubMed ID: 12960297
Glycosaminoglycan and proteoglycan inhibit the depolymerization of beta2-microglobulin amyloid fibrils in vitro.
Yamaguchi I, Suda H, Tsuzuike N, Seto K, Seki M, Yamaguchi Y, Hasegawa K, Takahashi N, Yamamoto S, Gejyo F, Naiki H
Kidney Int. 2003
PubMed ID: 12911560
Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor.
Willcox BE, Thomas LM, Bjorkman PJ
Nat Immunol. 2003
PubMed ID: 12897781
Molecular dynamics simulations of the unfolding of beta(2)-microglobulin and its variants.
Ma B, Nussinov R
Protein Eng. 2003
PubMed ID: 12968074
Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A.
Zajonc DM, Elsliger MA, Teyton L, Wilson IA
Nat Immunol. 2003
PubMed ID: 12833155
Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model.
Hiramatsu H, Nishikomori R, Heike T, Ito M, Kobayashi K, Katamura K, Nakahata T
Blood. 2003
PubMed ID: 12689924
A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation.
Smith DP, Jones S, Serpell LC, Sunde M, Radford SE
J Mol Biol. 2003
PubMed ID: 12860118
Role of the N and C-terminal strands of beta 2-microglobulin in amyloid formation at neutral pH.
Jones S, Smith DP, Radford SE
J Mol Biol. 2003
PubMed ID: 12860117
Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy.
Kad NM, Myers SL, Smith DP, Smith DA, Radford SE, Thomson NH
J Mol Biol. 2003
PubMed ID: 12850147
Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balan
Emoto M, Emoto Y, Brinkmann V, Miyamoto M, Yoshizawa I, Stäber M, van Rooijen N, Hamann A, Kaufmann SH
J Immunol. 2003
PubMed ID: 12847222
Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation.
Delamarre L, Holcombe H, Mellman I
J Exp Med. 2003
PubMed ID: 12835477
A structural basis for immunodominant human T cell receptor recognition.
Stewart-Jones GB, McMichael AJ, Bell JI, Stuart DI, Jones EY
Nat Immunol. 2003
PubMed ID: 12796775
Beta2-microglobulin amyloidosis: insights from conservation analysis and fibril modelling by protein docking techniques.
Benyamini H, Gunasekaran K, Wolfson H, Nussinov R
J Mol Biol. 2003
PubMed ID: 12818210
NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells.
Elewaut D, Shaikh RB, Hammond KJ, De Winter H, Leishman AJ, Sidobre S, Turovskaya O, Prigozy TI, Ma L, Banks TA, Lo D, Ware CF, Cheroutre H, Kronenberg M
J Exp Med. 2003
PubMed ID: 12810685
Beta 2 microglobulin knockout mice are resistant to lethal intraabdominal sepsis.
Sherwood ER, Lin CY, Tao W, Hartmann CA, Dujon JE, French AJ, Varma TK
Am J Respir Crit Care Med. 2003
PubMed ID: 12626348
IL-15 is an essential mediator of peripheral NK-cell homeostasis.
Ranson T, Vosshenrich CA, Corcuff E, Richard O, Müller W, Di Santo JP
Blood. 2003
PubMed ID: 12586624
Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.
TeKippe M, Harrison DE, Chen J
Exp Hematol. 2003
PubMed ID: 12829028
Selective absence of CD8+ TCRalpha beta+ intestinal epithelial cells in transgenic mice expressing beta2-microglobulin-associated ligands exclusively on thymic cortical epithelium.
Capone M, Lees RK, Finke D, Ernst B, Meerwijk JP, MacDonald HR
Eur J Immunol. 2003
PubMed ID: 12778464
Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes.
Lotem J, Gal H, Kama R, Amariglio N, Rechavi G, Domany E, Sachs L, Givol D
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12743373
Beta 2-microglobulin as a negative regulator of the immune system: high concentrations of the protein inhibit in vitro generation of functional dendritic cells.
Xie J, Wang Y, Freeman ME, Barlogie B, Yi Q
Blood. 2003
PubMed ID: 12531797
On the role of MHC class II molecules in the survival and lymphopenia-induced proliferation of peripheral CD4+ T cells.
Martin B, Bourgeois C, Dautigny N, Lucas B
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12719530
Evaluation of cystatin C and beta-2 microglobulin as markers of renal function in patients with type 2 diabetes mellitus.
Mojiminiyi OA, Abdella N
J Diabetes Complications. 2003
PubMed ID: 12738401
Regulation of human beta 2-microglobulin transactivation in hematopoietic cells.
Gobin SJ, Biesta P, Van den Elsen PJ
Blood. 2003
PubMed ID: 12480693
Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells.
Haks MC, Belkowski SM, Ciofani M, Rhodes M, Lefebvre JM, Trop S, Hugo P, Zúñiga-Pflücker JC, Wiest DL
J Immunol. 2003
PubMed ID: 12626535
The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin.
Wang J, Chen G, Pantopoulos K
Biochem J. 2003
PubMed ID: 12464008
Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1.
Treiner E, Duban L, Bahram S, Radosavljevic M, Wanner V, Tilloy F, Affaticati P, Gilfillan S, Lantz O
Nature. 2003
PubMed ID: 12634786
Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules.
Loconto J, Papes F, Chang E, Stowers L, Jones EP, Takada T, Kumánovics A, Fischer Lindahl K, Dulac C
Cell. 2003
PubMed ID: 12628182
IL-15 availability conditions homeostasis of peripheral natural killer T cells.
Ranson T, Vosshenrich CA, Corcuff E, Richard O, Laloux V, Lehuen A, Di Santo JP
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12598649
Complete loss of HLA class I antigen expression on melanoma cells: a result of successive mutational events.
Paschen A, Méndez RM, Jimenez P, Sucker A, Ruiz-Cabello F, Song M, Garrido F, Schadendorf D
Int J Cancer. 2003
PubMed ID: 12516095
A dominant negative mutant beta 2-microglobulin blocks the extracellular folding of a major histocompatibility complex class I heavy chain.
Hill DM, Kasliwal T, Schwarz E, Hebert AM, Chen T, Gubina E, Zhang L, Kozlowski S
J Biol Chem. 2003
PubMed ID: 12454016
CD8+ T cells accumulate in the lungs of Mycobacterium tuberculosis-infected Kb-/-Db-/- mice, but provide minimal protection.
Urdahl KB, Liggitt D, Bevan MJ
J Immunol. 2003
PubMed ID: 12574368
The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan.
Chaudhury C, Mehnaz S, Robinson JM, Hayton WL, Pearl DK, Roopenian DC, Anderson CL
J Exp Med. 2003
PubMed ID: 12566415
Disparate peptide-dependent thymic selection outcomes in beta2M-deficient mice versus TAP-1-deficient mice: implications for repertoire formation.
Sasada T, Yang Y, Lai CC, Touma M, Clayton LK, Liu JH, Parisini E, Wang JH, Reinherz EL
Eur J Immunol. 2003
PubMed ID: 12645934
Beta2-microglobulin aberrations in diffuse large B-cell lymphoma of the testis and the central nervous system.
Jordanova ES, Riemersma SA, Philippo K, Schuuring E, Kluin PM
Int J Cancer. 2003
PubMed ID: 12471623
Amyloid-forming peptides from beta2-microglobulin-Insights into the mechanism of fibril formation in vitro.
Jones S, Manning J, Kad NM, Radford SE
J Mol Biol. 2003
PubMed ID: 12488093
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis.
McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M
Mol Cell Biol. 2003
PubMed ID: 12482959
Cellular uptake of beta2M and AGE-beta2M in synovial fibroblasts and macrophages.
O'Neill KD, Chen NX, Wang M, Cocklin R, Zhang Y, Moe SM
Nephrol Dial Transplant. 2003
PubMed ID: 12480959
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.
Kontoyiannis D, Boulougouris G, Manoloukos M, Armaka M, Apostolaki M, Pizarro T, Kotlyarov A, Forster I, Flavell R, Gaestel M, Tsichlis P, Cominelli F, Kollias G
J Exp Med. 2002
PubMed ID: 12486099
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis.
Schaible UE, Collins HL, Priem F, Kaufmann SH
J Exp Med. 2002
PubMed ID: 12461085
The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis.
Corr M, Crain B
J Immunol. 2002
PubMed ID: 12444173
Bone marrow B cell apoptosis during in vivo influenza virus infection requires TNF-alpha and lymphotoxin-alpha.
Sedger LM, Hou S, Osvath SR, Glaccum MB, Peschon JJ, van Rooijen N, Hyland L
J Immunol. 2002
PubMed ID: 12444124
Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate.
Cannon JP, Haire RN, Litman GW
Nat Immunol. 2002
PubMed ID: 12415263
NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells.
Ito M, Hiramatsu H, Kobayashi K, Suzue K, Kawahata M, Hioki K, Ueyama Y, Koyanagi Y, Sugamura K, Tsuji K, Heike T, Nakahata T
Blood. 2002
PubMed ID: 12384415
The heavy chain of neonatal Fc receptor for IgG is sequestered in endoplasmic reticulum by forming oligomers in the absence of beta2-microglobulin association.
Zhu X, Peng J, Raychowdhury R, Nakajima A, Lencer WI, Blumberg RS
Biochem J. 2002
PubMed ID: 12162790
Fast-twitch skeletal muscles of dystrophic mouse pups are resistant to injury from acute mechanical stress.
Grange RW, Gainer TG, Marschner KM, Talmadge RJ, Stull JT
Am J Physiol Cell Physiol. 2002
PubMed ID: 12225973
Peptidic termini play a significant role in TCR recognition.
Wang B, Sharma A, Maile R, Saad M, Collins EJ, Frelinger JA
J Immunol. 2002
PubMed ID: 12218131
The role of disulfide bond in the amyloidogenic state of beta(2)-microglobulin studied by heteronuclear NMR.
Katou H, Kanno T, Hoshino M, Hagihara Y, Tanaka H, Kawai T, Hasegawa K, Naiki H, Goto Y
Protein Sci. 2002
PubMed ID: 12192077
Effect of iron status on DMT1 expression in duodenal enterocytes from beta2-microglobulin knockout mice.
Moos T, Trinder D, Morgan EH
Am J Physiol Gastrointest Liver Physiol. 2002
PubMed ID: 12181184
A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development.
Fowlkes BJ, Robey EA
J Immunol. 2002
PubMed ID: 12165504
Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulin.
Claypool SM, Dickinson BL, Yoshida M, Lencer WI, Blumberg RS
J Biol Chem. 2002
PubMed ID: 12023961
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Gadola SD, Zaccai NR, Harlos K, Shepherd D, Castro-Palomino JC, Ritter G, Schmidt RR, Jones EY, Cerundolo V
Nat Immunol. 2002
PubMed ID: 12118248
Crystal structure of monomeric human beta-2-microglobulin reveals clues to its amyloidogenic properties.
Trinh CH, Smith DP, Kalverda AP, Phillips SE, Radford SE
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12119416
The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development.
Graf D, Nethisinghe S, Palmer DB, Fisher AG, Merkenschlager M
J Exp Med. 2002
PubMed ID: 12119341
Thymic and extrathymic T cell development pathways follow different rules.
Terra R, Labrecque N, Perreault C
J Immunol. 2002
PubMed ID: 12097370
Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system.
Hobbs NK, Bondareva AA, Barnett S, Capecchi MR, Schmidt EE
Cell. 2002
PubMed ID: 12150996
Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin.
Sullivan BA, Kraj P, Weber DA, Ignatowicz L, Jensen PE
Immunity. 2002
PubMed ID: 12150895
Skin graft rejection elicited by beta 2-microglobulin as a minor transplantation antigen involves multiple effector pathways: role of Fas-Fas ligand interactions and Th2-dependent graft eosinophil infiltrates.
Surquin M, Le Moine A, Flamand V, Nagy N, Rombaut K, Demoor FX, Stordeur P, Salmon I, Guéry JC, Goldman M, Abramowicz D
J Immunol. 2002
PubMed ID: 12077281
Increased expression of beta 2-microglobulin in multidrug-resistant tumour cells.
Scheffer GL, de Jong MC, Monks A, Flens MJ, Hose CD, Izquierdo MA, Shoemaker RH, Scheper RJ
Br J Cancer. 2002
PubMed ID: 12085191
Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells.
Kieper WC, Tan JT, Bondi-Boyd B, Gapin L, Sprent J, Ceredig R, Surh CD
J Exp Med. 2002
PubMed ID: 12070281
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor.
Aguado E, Richelme S, Nuñez-Cruz S, Miazek A, Mura AM, Richelme M, Guo XJ, Sainty D, He HT, Malissen B, Malissen M
Science. 2002
PubMed ID: 12065839
Conformation of beta 2-microglobulin amyloid fibrils analyzed by reduction of the disulfide bond.
Hong DP, Gozu M, Hasegawa K, Naiki H, Goto Y
J Biol Chem. 2002
PubMed ID: 11943769
Novel CD8+ T cell antagonists based on beta 2-microglobulin.
Glick M, Price DA, Vuidepot AL, Andersen TB, Hutchinson SL, Laugel B, Sewell AK, Boulter JM, Dunbar PR, Cerundolo V, Oxenius A, Bell JI, Richards WG, Jakobsen BK
J Biol Chem. 2002
PubMed ID: 11914379
Phylogenetic relationships in the genus mus, based on paternally, maternally, and biparentally inherited characters.
Lundrigan BL, Jansa SA, Tucker PK
Syst Biol. 2002
PubMed ID: 12079642
beta(2)-Microglobulin is important for cell surface expression and pH-dependent IgG binding of human FcRn.
Praetor A, Hunziker W
J Cell Sci. 2002
PubMed ID: 12006623
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.
Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD
Science. 2002
PubMed ID: 12040188
Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.
Reynolds LF, Smyth LA, Norton T, Freshney N, Downward J, Kioussis D, Tybulewicz VL
J Exp Med. 2002
PubMed ID: 11994416
Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2.
Myrick C, DiGuisto R, DeWolfe J, Bowen E, Kappler J, Marrack P, Wakeland EK
Genes Immun. 2002
PubMed ID: 12070778
Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange.
Hoshino M, Katou H, Hagihara Y, Hasegawa K, Naiki H, Goto Y
Nat Struct Biol. 2002
PubMed ID: 11967567
Structural properties of an amyloid precursor of beta(2)-microglobulin.
McParland VJ, Kalverda AP, Homans SW, Radford SE
Nat Struct Biol. 2002
PubMed ID: 11967566
Presence of a novel subset of NKT cells bearing an invariant V(alpha)19.1-J(alpha)26 TCR alpha chain.
Shimamura M, Huang YY
FEBS Lett. 2002
PubMed ID: 11959111
Ganglioside expression in tissues of mice lacking beta2-microglobulin.
Markotić A, Marusić A, Tomac J, Müthing J
Clin Exp Immunol. 2002
PubMed ID: 11982587
Cleaved beta 2-microglobulin partially attains a conformation that has amyloidogenic features.
Heegaard NH, Roepstorff P, Melberg SG, Nissen MH
J Biol Chem. 2002
PubMed ID: 11801591
Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation.
Avet-Loiseau H, Facon T, Grosbois B, Magrangeas F, Rapp MJ, Harousseau JL, Minvielle S, Bataille R, Intergroupe Francophone du Myélome
Blood. 2002
PubMed ID: 11877296
Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells.
Krawczyk C, Oliveira-dos-Santos A, Sasaki T, Griffiths E, Ohashi PS, Snapper S, Alt F, Penninger JM
Immunity. 2002
PubMed ID: 11911819
Up-regulation of MHC class I expression accompanies but is not required for spontaneous myopathy in dysferlin-deficient SJL/J mice.
Kostek CA, Dominov JA, Miller JB
Am J Pathol. 2002
PubMed ID: 11891182
A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors.
Lowin-Kropf B, Kunz B, Schneider P, Held W
Eur J Immunol. 2002
PubMed ID: 11870621
The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Verdone G, Corazza A, Viglino P, Pettirossi F, Giorgetti S, Mangione P, Andreola A, Stoppini M, Bellotti V, Esposito G
Protein Sci. 2002
PubMed ID: 11847272
Signal transduction of beta2m-induced expression of VCAM-1 and COX-2 in synovial fibroblasts.
Chen NX, O'Neill KD, Niwa T, Moe SM
Kidney Int. 2002
PubMed ID: 11849381
Enforced expression of the Ikaros isoform IK5 decreases the numbers of extrathymic intraepithelial lymphocytes and natural killer 1.1+ T cells.
Tucker SN, Jessup HK, Fujii H, Wilson CB
Blood. 2002
PubMed ID: 11781232
Peptide specificity of thymic selection of CD4+CD25+ T cells.
Pacholczyk R, Kraj P, Ignatowicz L
J Immunol. 2002
PubMed ID: 11777953
Preservation of neurologic function during inflammatory demyelination correlates with axon sparing in a mouse model of multiple sclerosis.
Ure DR, Rodriguez M
Neuroscience. 2002
PubMed ID: 11983325
Lineage fate alteration of thymocytes developing in an MHC environment containing MHC/peptide ligands with antagonist properties.
Barthlott T, Stockinger B
Eur J Immunol. 2001
PubMed ID: 11745379
Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation.
He X, Tabaczewski P, Ho J, Stroynowski I, Garcia KC
Structure. 2001
PubMed ID: 11738047
A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.
Farmer MA, Sundberg JP, Bristol IJ, Churchill GA, Li R, Elson CO, Leiter EH
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11707574
H-2D ligand expression by Ly49A+ natural killer (NK) cells precludes ligand uptake from environmental cells: implications for NK cell function.
Zimmer J, Ioannidis V, Held W
J Exp Med. 2001
PubMed ID: 11714759
Abundance of unconventional CD8(+) natural killer T cells in the large intestine.
Bannai M, Kawamura T, Naito T, Kameyama H, Abe T, Kawamura H, Tsukada C, Watanabe H, Hatakeyama K, Hamada H, Nishiyama Y, Ishikawa H, Takeda K, Okumura K, Taniguchi M, Abo T
Eur J Immunol. 2001
PubMed ID: 11745354
Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage.
Zou YR, Sunshine MJ, Taniuchi I, Hatam F, Killeen N, Littman DR
Nat Genet. 2001
PubMed ID: 11687799
Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro.
Kad NM, Thomson NH, Smith DP, Smith DA, Radford SE
J Mol Biol. 2001
PubMed ID: 11676539
Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production.
Ikarashi Y, Mikami R, Bendelac A, Terme M, Chaput N, Terada M, Tursz T, Angevin E, Lemonnier FA, Wakasugi H, Zitvogel L
J Exp Med. 2001
PubMed ID: 11602646
Different requirements for alpha-galactosylceramide and recombinant IL-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases.
Chiodoni C, Stoppacciaro A, Sangaletti S, Gri G, Cappetti B, Koezuka Y, Colombo MP
Eur J Immunol. 2001
PubMed ID: 11592087
Design of a polyepitope construct for the induction of HLA-A0201-restricted HIV 1-specific CTL responses using HLA-A*0201 transgenic, H-2 class I KO mice.
Firat H, Tourdot S, Ureta-Vidal A, Scardino A, Suhrbier A, Buseyne F, Rivìere Y, Danos O, Michel ML, Kosmatopoulos K, Lemonnier FA
Eur J Immunol. 2001
PubMed ID: 11592083
Molecular genetics of ulcerative colitis-associated colon cancer in the interleukin 2- and beta(2)-microglobulin-deficient mouse.
Sohn KJ, Shah SA, Reid S, Choi M, Carrier J, Comiskey M, Terhorst C, Kim YI
Cancer Res. 2001
PubMed ID: 11559569
A study of factors related to the incidence of cataract in patients with non-insulin dependent diabetes mellitus.
Xia X, Zhang X, Xia H
Yan Ke Xue Bao. 2001
PubMed ID: 12567748
Deficiency in beta(2)-microglobulin, but not CD1, accelerates spontaneous lupus skin disease while inhibiting nephritis in MRL-Fas(lpr) nice: an example of disease regulation at the organ level.
Chan OT, Paliwal V, McNiff JM, Park SH, Bendelac A, Shlomchik MJ
J Immunol. 2001
PubMed ID: 11509649
The source of early IFN-gamma that plays a role in Th1 priming.
Das G, Sheridan S, Janeway CA
J Immunol. 2001
PubMed ID: 11489982
Viral load increases in SJL/J mice persistently infected by Theiler's virus after inactivation of the beta(2)m gene.
Aubagnac S, Brahic M, Bureau JF
J Virol. 2001
PubMed ID: 11462045
High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene.
Hillig RC, Coulie PG, Stroobant V, Saenger W, Ziegler A, Hülsmeyer M
J Mol Biol. 2001
PubMed ID: 11502003
IL-7 is critical for homeostatic proliferation and survival of naive T cells.
Tan JT, Dudl E, LeRoy E, Murray R, Sprent J, Weinberg KI, Surh CD
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11447288
Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules.
Maurice MM, Gould DS, Carroll J, Vugmeyster Y, Ploegh HL
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11404484
Structural basis of MHC class I recognition by natural killer cell receptors.
Sawicki MW, Dimasi N, Natarajan K, Wang J, Margulies DH, Mariuzza RA
Immunol Rev. 2001
PubMed ID: 11513152
MHC class Ia-restricted T cells partially account for beta2-microglobulin-dependent resistance to Mycobacterium tuberculosis.
Rolph MS, Raupach B, Köbernick HH, Collins HL, Pérarnau B, Lemonnier FA, Kaufmann SH
Eur J Immunol. 2001
PubMed ID: 11433392
Differential involvement of dendritic cell subsets during acute Salmonella infection.
Kirby AC, Yrlid U, Svensson M, Wick MJ
J Immunol. 2001
PubMed ID: 11359839
MHC class I-Ly49 interactions shape the Ly49 repertoire on murine NK cells.
Fahlén L, Lendahl U, Sentman CL
J Immunol. 2001
PubMed ID: 11359811
Overexpressing human lipoprotein lipase in mouse skeletal muscle is associated with insulin resistance.
Ferreira LD, Pulawa LK, Jensen DR, Eckel RH
Diabetes. 2001
PubMed ID: 11334409
Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta 2-microglobulin-deficient mice.
Sproule TJ, Jazwinska EC, Britton RS, Bacon BR, Fleming RE, Sly WS, Roopenian DC
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11309500
Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk).
Schmedt C, Tarakhovsky A
J Exp Med. 2001
PubMed ID: 11283154
Regulation of experimental autoimmune encephalomyelitis in the C57BL/6J mouse by NK1.1+, DX5+, alpha beta+ T cells.
Fritz RB, Zhao ML
J Immunol. 2001
PubMed ID: 11238673
Cutting edge: regulation of uterine NKT cells by a fetal class I molecule other than CD1.
Dang Y, Heyborne KD
J Immunol. 2001
PubMed ID: 11238600
Spontaneous inflammatory disease in HLA-B27 transgenic mice does not require transporter of antigenic peptides.
Khare SD, Lee S, Bull MJ, Hanson J, Luthra HS, David CS
Clin Immunol. 2001
PubMed ID: 11237560
Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells.
Capone M, Romagnoli P, Beermann F, MacDonald HR, van Meerwijk JP
Blood. 2001
PubMed ID: 11222378
Involvement of CD1 in peripheral deletion of T lymphocytes is independent of NK T cells.
Dao T, Exley M, Mehal WZ, Tahir SM, Snapper S, Taniguchi M, Balk SP, Crispe IN
J Immunol. 2001
PubMed ID: 11207260
Activated p56lck directs maturation of both CD4 and CD8 single-positive thymocytes.
Sohn SJ, Forbush KA, Pan XC, Perlmutter RM
J Immunol. 2001
PubMed ID: 11160274
Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.
Canonne-Hergaux F, Levy JE, Fleming MD, Montross LK, Andrews NC, Gros P
Blood. 2001
PubMed ID: 11159549
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Use of knockout transgenic mice in the study of endometriosis: insights from mice lacking beta(2)-microglobulin and interleukin-12p40.
Somigliana E, Viganò P, Filardo P, Candiani M, Vignali M, Panina-Bordignon P
Fertil Steril. 2001
PubMed ID: 11163839
Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.
Speir JA, Stevens J, Joly E, Butcher GW, Wilson IA
Immunity. 2001
PubMed ID: 11163232
Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice.
Glimm H, Eisterer W, Lee K, Cashman J, Holyoake TL, Nicolini F, Shultz LD, von Kalle C, Eaves CJ
J Clin Invest. 2001
PubMed ID: 11160136
Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-1.
D'Orazio TJ, Mayhew E, Niederkorn JY
J Immunol. 2001
PubMed ID: 11123273
Functional requirement for class I MHC in CNS development and plasticity.
Huh GS, Boulanger LM, Du H, Riquelme PA, Brotz TM, Shatz CJ
Science. 2000
PubMed ID: 11118151
Diversity of T cell repertoire shaped by a single peptide ligand is critically affected by its amino acid residue at a T cell receptor contact.
Fukui Y, Oono T, Cabaniols JP, Nakao K, Hirokawa K, Inayoshi A, Sanui T, Kanellopoulos J, Iwata E, Noda M, Katsuki M, Kourilsky P, Sasazuki T
Proc Natl Acad Sci U S A. 2000
PubMed ID: 11087837
Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors.
Lepin EJ, Bastin JM, Allan DS, Roncador G, Braud VM, Mason DY, van der Merwe PA, McMichael AJ, Bell JI, Powis SH, O'Callaghan CA
Eur J Immunol. 2000
PubMed ID: 11169396
Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels.
Lahbib-Mansais Y, Leroux S, Milan D, Yerle M, Robic A, Jiang Z, André C, Gellin J
Mamm Genome. 2000
PubMed ID: 11130978
Iron overload and heart fibrosis in mice deficient for both beta2-microglobulin and Rag1.
Santos MM, de Sousa M, Rademakers LH, Clevers H, Marx JJ, Schilham MW
Am J Pathol. 2000
PubMed ID: 11106561
Characterization of CD1e, a third type of CD1 molecule expressed in dendritic cells.
Angenieux C, Salamero J, Fricker D, Cazenave JP, Goud B, Hanau D, de La Salle H
J Biol Chem. 2000
PubMed ID: 10948205
Thymic epithelial cells responsible for impaired generation of NK-T thymocytes in Alymphoplasia mutant mice.
Konishi J, Iwabuchi K, Iwabuchi C, Ato M, Nagata JI, Onoé K, Nakagawa KI, Kasai M, Ogasawara K, Kawakami K, Onoé K
Cell Immunol. 2000
PubMed ID: 11161435
CD8(+) T cell knockout mice are less susceptible to Cowdria ruminantium infection than athymic, CD4(+) T cell knockout, and normal C57BL/6 mice.
Byrom B, Barbet AF, Obwolo M, Mahan SM
Vet Parasitol. 2000
PubMed ID: 11035234
Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development.
Gouble A, Morello D
Oncogene. 2000
PubMed ID: 11103939
CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling.
Hida S, Ogasawara K, Sato K, Abe M, Takayanagi H, Yokochi T, Sato T, Hirose S, Shirai T, Taki S, Taniguchi T
Immunity. 2000
PubMed ID: 11114377
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Dendritic cells prime in vivo alloreactive CD4 T lymphocytes toward type 2 cytokine- and TGF-beta-producing cells in the absence of CD8 T cell activation.
Foucras G, Coudert JD, Coureau C, Guéry JC
J Immunol. 2000
PubMed ID: 11046027
Genetic dissection of primary and secondary responses to a widespread natural pathogen of the gut, Eimeria vermiformis.
Smith AL, Hayday AC
Infect Immun. 2000
PubMed ID: 11035735
Human CD1d associates with prolyl-4-hydroxylase during its biosynthesis.
Kim HS, Colgan SP, Pitman R, Hershberg RM, Blumberg RS
Mol Immunol. 2000
PubMed ID: 11257307
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Development of spontaneous arthritis in beta2-microglobulin-deficient mice without expression of HLA-B27: association with deficiency of endogenous major histocompatibility complex class I expression.
Kingsbury DJ, Mear JP, Witte DP, Taurog JD, Roopenian DC, Colbert RA
Arthritis Rheum. 2000
PubMed ID: 11037889
CD8+ T cells rapidly acquire NK1.1 and NK cell-associated molecules upon stimulation in vitro and in vivo.
Assarsson E, Kambayashi T, Sandberg JK, Hong S, Taniguchi M, Van Kaer L, Ljunggren HG, Chambers BJ
J Immunol. 2000
PubMed ID: 11034371
Chemokine gene expression in astrocytes of Borna disease virus-infected rats and mice in the absence of inflammation.
Sauder C, Hallensleben W, Pagenstecher A, Schneckenburger S, Biro L, Pertlik D, Hausmann J, Suter M, Staeheli P
J Virol. 2000
PubMed ID: 10982374
TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.
Yasutomo K, Lucas B, Germain RN
J Immunol. 2000
PubMed ID: 10975810
A NK1.1+ thymocyte-derived TCR beta-chain transgene promotes positive selection of thymic NK1.1+ alpha beta T cells.
Viret C, Lantz O, He X, Bendelac A, Janeway CA
J Immunol. 2000
PubMed ID: 10975809
Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,).
West AP, Bjorkman PJ
Biochemistry. 2000
PubMed ID: 10933786
Transgenic expression of Ly49A on T cells impairs a specific antitumor response.
Brawand P, Lemonnier FA, MacDonald HR, Cerottini JC, Held W
J Immunol. 2000
PubMed ID: 10925266
Response of murine gamma delta T cells to the synthetic polypeptide poly-Glu50Tyr50.
Cady CT, Lahn M, Vollmer M, Tsuji M, Seo SJ, Reardon CL, O'Brien RL, Born WK
J Immunol. 2000
PubMed ID: 10925256
Cutting edge: naive T cells masquerading as memory cells.
Murali-Krishna K, Ahmed R
J Immunol. 2000
PubMed ID: 10925249
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
A novel nonclassic beta2-microglobulin-restricted mechanism influencing early lymphocyte accumulation and subsequent resistance to tuberculosis in the lung.
D'Souza CD, Cooper AM, Frank AA, Ehlers S, Turner J, Bendelac A, Orme IM
Am J Respir Cell Mol Biol. 2000
PubMed ID: 10919985
Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration.
Lau AL, Kumar TR, Nishimori K, Bonadio J, Matzuk MM
Mol Cell Biol. 2000
PubMed ID: 10913194
Impaired natural killing of MHC class I-deficient targets by NK cells expressing a catalytically inactive form of SHP-1.
Lowin-Kropf B, Kunz B, Beermann F, Held W
J Immunol. 2000
PubMed ID: 10903732
Membrane lymphotoxin is required for the development of different subpopulations of NK T cells.
Elewaut D, Brossay L, Santee SM, Naidenko OV, Burdin N, De Winter H, Matsuda J, Ware CF, Cheroutre H, Kronenberg M
J Immunol. 2000
PubMed ID: 10878339
H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection.
Felix NJ, Brickey WJ, Griffiths R, Zhang J, Van Kaer L, Coffman T, Ting JP
J Exp Med. 2000
PubMed ID: 10880524
The role of CD8(+) T cells and major histocompatibility complex class I expression in the central nervous system of mice infected with neurovirulent Sindbis virus.
Kimura T, Griffin DE
J Virol. 2000
PubMed ID: 10846095
Effect of B2m gene disruption on MHC-determined odortypes.
Bard J, Yamazaki K, Curran M, Boyse EA, Beauchamp GK
Immunogenetics. 2000
PubMed ID: 10912502
Generation of alphabeta T-cell receptor+ CD4- CD8+ cells in major histocompatibility complex class I-deficient mice upon activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Kronenberg S, Lai Z, Esser C
Immunology. 2000
PubMed ID: 10886394
Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction.
Lode HN, Xiang R, Pertl U, Förster E, Schoenberger SP, Gillies SD, Reisfeld RA
J Clin Invest. 2000
PubMed ID: 10841521
Genes that modify the hemochromatosis phenotype in mice.
Levy JE, Montross LK, Andrews NC
J Clin Invest. 2000
PubMed ID: 10791995
Lethal host-versus-graft disease and hypereosinophilia in the absence of MHC I-T-cell interactions.
Coudert JD, Foucras G, Demur C, Coureau C, Mazerolles C, Delsol G, Druet P, Guéry JC
J Clin Invest. 2000
PubMed ID: 10772657
alpha2-Macroglobulin, the main serum antiprotease, binds beta2-microglobulin, the light chain of the class I major histocompatibility complex, which is involved in human disease.
Gouin-Charnet A, Laune D, Granier C, Mani JC, Pau B, Mourad G, Argilés A
Clin Sci (Lond). 2000
PubMed ID: 10731476
Altered aging-related thymic involution in T cell receptor transgenic, MHC-deficient, and CD4-deficient mice.
Lau LL, Spain LM
Mech Ageing Dev. 2000
PubMed ID: 10799708
Beta 2-microglobulin/CD8 -/- mice reveal significant role for CD8+ T cells in graft rejection responses in beta 2-microglobulin -/- mice.
Freland S, Ljunggren HG
Scand J Immunol. 2000
PubMed ID: 10736089
NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.
Coles MC, Raulet DH
J Immunol. 2000
PubMed ID: 10679077
Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B.
Ho LH, Uehara T, Chen CC, Kubagawa H, Cooper MD
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10611342
The selection of M3-restricted T cells is dependent on M3 expression and presentation of N-formylated peptides in the thymus.
Chiu NM, Wang B, Kerksiek KM, Kurlander R, Pamer EG, Wang CR
J Exp Med. 1999
PubMed ID: 10601361
Coupling and uncoupling of tumor immunity and autoimmunity.
Bowne WB, Srinivasan R, Wolchok JD, Hawkins WG, Blachere NE, Dyall R, Lewis JJ, Houghton AN
J Exp Med. 1999
PubMed ID: 10587362
Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47.
Bain G, Quong MW, Soloff RS, Hedrick SM, Murre C
J Exp Med. 1999
PubMed ID: 10587351
CD4(+) T cell-mediated protection against a lethal outcome of systemic infection with vesicular stomatitis virus requires CD40 ligand expression, but not IFN-gamma or IL-4.
Andersen C, Jensen T, Nansen A, Marker O, Thomsen AR
Int Immunol. 1999
PubMed ID: 10590269
Heterogeneity of NK1.1+ T cells in the bone marrow: divergence from the thymus.
Zeng D, Gazit G, Dejbakhsh-Jones S, Balk SP, Snapper S, Taniguchi M, Strober S
J Immunol. 1999
PubMed ID: 10553057
Persistence of memory CD8 T cells in MHC class I-deficient mice.
Murali-Krishna K, Lau LL, Sambhara S, Lemonnier F, Altman J, Ahmed R
Science. 1999
PubMed ID: 10558996
Regulation of lineage commitment distinct from positive selection.
Keefe R, Dave V, Allman D, Wiest D, Kappes DJ
Science. 1999
PubMed ID: 10550051
The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency.
Huang L, Kuo YM, Gitschier J
Nat Genet. 1999
PubMed ID: 10610180
The Src family tyrosine kinase Fyn regulates natural killer T cell development.
Gadue P, Morton N, Stein PL
J Exp Med. 1999
PubMed ID: 10523617
Beta(2)-microglobulin identified as an apoptosis-inducing factor and its characterization.
Mori M, Terui Y, Ikeda M, Tomizuka H, Uwai M, Kasahara T, Kubota N, Itoh T, Mishima Y, Douzono-Tanaka M, Yamada M, Shimamura S, Kikuchi J, Furukawa Y, Ishizaka Y, Ikeda K, Mano H, Ozawa K, Hatake K
Blood. 1999
PubMed ID: 10515878
Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin.
Marguerat S, MacDonald HR, Kraehenbuhl JP, van Meerwijk JP
J Immunol. 1999
PubMed ID: 10491007
Beta 2-microglobulin-deficient background ameliorates lethal phenotype of the TGF-beta 1 null mouse.
Kobayashi S, Yoshida K, Ward JM, Letterio JJ, Longenecker G, Yaswen L, Mittleman B, Mozes E, Roberts AB, Karlsson S, Kulkarni AB
J Immunol. 1999
PubMed ID: 10491004
NK and CTL recognition of a single chain H-2Dd molecule: distinct sites of H-2Dd interact with NK and TCR.
Chung DH, Dorfman J, Plaksin D, Natarajan K, Belyakov IM, Hunziker R, Berzofsky JA, Yokoyama WM, Mage MG, Margulies DH
J Immunol. 1999
PubMed ID: 10490965
Selection and expansion of CD8alpha/alpha(1) T cell receptor alpha/beta(1) intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and nonclassical CD1 molecules.
Park SH, Guy-Grand D, Lemonnier FA, Wang CR, Bendelac A, Jabri B
J Exp Med. 1999
PubMed ID: 10499927
Differential control of autoantibodies and lymphoproliferation by Fas ligand expression on CD4+ and CD8+ T cells in vivo.
Maldonado MA, MacDonald GC, Kakkanaiah VN, Fecho K, Dransfield M, Sekiguchi D, Cohen PL, Eisenberg RA
J Immunol. 1999
PubMed ID: 10477580
Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells.
Steinhoff U, Brinkmann V, Klemm U, Aichele P, Seiler P, Brandt U, Bland PW, Prinz I, Zügel U, Kaufmann SH
Immunity. 1999
PubMed ID: 10514013
Perforin-dependent cytolytic responses in beta2-microglobulin-deficient mice.
Smyth MJ, Snook MB
Cell Immunol. 1999
PubMed ID: 10486155
Regulatory role of peritoneal NK1.1+ alpha beta T cells in IL-12 production during Salmonella infection.
Naiki Y, Nishimura H, Kawano T, Tanaka Y, Itohara S, Taniguchi M, Yoshikai Y
J Immunol. 1999
PubMed ID: 10438944
Effect on parasite eradication of Pneumocystis carinii-specific antibodies produced in the presence or absence of CD4(+) alphabeta T lymphocytes.
Hanano R, Kaufmann SH
Eur J Immunol. 1999
PubMed ID: 10458760
Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage commitment in the thymus.
Bommhardt U, Basson MA, Krummrei U, Zamoyska R
J Immunol. 1999
PubMed ID: 10395662
Positive selection of an H2-M3 restricted T cell receptor.
Berg RE, Princiotta MF, Irion S, Moticka JA, Dahl KR, Staerz UD
Immunity. 1999
PubMed ID: 10435577
Differing MHC class I requirements for induction and propagation of experimental systemic lupus erythematosus.
Singer DS, Zinger H, Kohn LD, Mozes E
Eur J Immunol. 1999
PubMed ID: 10427989
A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system.
Tomura M, Yu WG, Ahn HJ, Yamashita M, Yang YF, Ono S, Hamaoka T, Kawano T, Taniguchi M, Koezuka Y, Fujiwara H
J Immunol. 1999
PubMed ID: 10384104
Cytolytic and IFN-gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are T cell receptor-beta-chain dependent.
Kohyama M, Nanno M, Kawaguchi-Miyashita M, Shimada S, Watanabe M, Hibi T, Kaminogawa S, Ishikawa H
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10377435
An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals.
Tilloy F, Treiner E, Park SH, Garcia C, Lemonnier F, de la Salle H, Bendelac A, Bonneville M, Lantz O
J Exp Med. 1999
PubMed ID: 10377186
Critical role of leukocyte function-associated antigen-1 in liver accumulation of CD4+NKT cells.
Emoto M, Mittrücker HW, Schmits R, Mak TW, Kaufmann SH
J Immunol. 1999
PubMed ID: 10227978
Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form.
Somnay-Wadgaonkar K, Nusrat A, Kim HS, Canchis WP, Balk SP, Colgan SP, Blumberg RS
Int Immunol. 1999
PubMed ID: 10221650
Peptide dependency of alloreactive CD4+ T cell responses.
Mendiratta SK, Kovalik JP, Hong S, Singh N, Martin WD, Van Kaer L
Int Immunol. 1999
PubMed ID: 10221647
A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice.
Kassiotis G, Bauer J, Akassoglou K, Lassmann H, Kollias G, Probert L
Eur J Immunol. 1999
PubMed ID: 10092095
Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice.
Rottenberg ME, Gigliotti Rothfuchs AC, Gigliotti D, Svanholm C, Bandholtz L, Wigzell H
J Immunol. 1999
PubMed ID: 10072530
Isoforms of the Na-K-2Cl cotransporter in murine TAL I. Molecular characterization and intrarenal localization.
Mount DB, Baekgaard A, Hall AE, Plata C, Xu J, Beier DR, Gamba G, Hebert SC
Am J Physiol. 1999
PubMed ID: 10070158
Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity.
Kehren J, Desvignes C, Krasteva M, Ducluzeau MT, Assossou O, Horand F, Hahne M, Kägi D, Kaiserlian D, Nicolas JF
J Exp Med. 1999
PubMed ID: 10049941
Cellular reservoirs for coronavirus infection of the brain in beta2-microglobulin knockout mice.
Lavi E, Das Sarma J, Weiss SR
Pathobiology. 1999
PubMed ID: 10023135
MHC class II-dependent NK1.1+ gammadelta T cells are induced in mice by Salmonella infection.
Nishimura H, Washizu J, Naiki Y, Hara T, Fukui Y, Sasazuki T, Yoshikai Y
J Immunol. 1999
PubMed ID: 9973415
Timing and casting for actors of thymic negative selection.
Dautigny N, Le Campion A, Lucas B
J Immunol. 1999
PubMed ID: 9973382
Cell surface expression of HLA-E: interaction with human beta2-microglobulin and allelic differences.
Ulbrecht M, Couturier A, Martinozzi S, Pla M, Srivastava R, Peterson PA, Weiss EH
Eur J Immunol. 1999
PubMed ID: 10064069
Genes regulating MHC class I processing of antigen.
van Endert PM
Curr Opin Immunol. 1999
PubMed ID: 10047538
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Visualization of CD4/CD8 T cell commitment.
Chan S, Correia-Neves M, Dierich A, Benoist C, Mathis D
J Exp Med. 1998
PubMed ID: 9858518
Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses.
Ermak TH, Giannasca PJ, Nichols R, Myers GA, Nedrud J, Weltzin R, Lee CK, Kleanthous H, Monath TP
J Exp Med. 1998
PubMed ID: 9858514
Beta 2-microglobulin knockout mice are highly susceptible to polyoma virus tumorigenesis.
Drake DR, Lukacher AE
Virology. 1998
PubMed ID: 9875336
HIV Tat represses transcription of the beta 2-microglobulin promoter.
Carroll IR, Wang J, Howcroft TK, Singer DS
Mol Immunol. 1998
PubMed ID: 10199391
CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice.
Van de Keere F, Tonegawa S
J Exp Med. 1998
PubMed ID: 9815265
The homogeneity of the TCRdelta repertoire expressed by the Thy-1dull gammadelta T cell population is due to cellular selection.
Azuara V, Lembezat MP, Pereira P
Eur J Immunol. 1998
PubMed ID: 9842888
Induction of thymocyte apoptosis by Ca2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation.
Asada A, Zhao Y, Kondo S, Iwata M
J Biol Chem. 1998
PubMed ID: 9774466
Functional comparison of bovine, murine, and human beta2-microglobulin: interactions with murine MHC I molecules.
Shields MJ, Moffat LE, Ribaudo RK
Mol Immunol. 1998
PubMed ID: 9881687
HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.
Weissman JD, Brown JA, Howcroft TK, Hwang J, Chawla A, Roche PA, Schiltz L, Nakatani Y, Singer DS
Proc Natl Acad Sci U S A. 1998
PubMed ID: 9751712
Highly restricted T cell repertoire shaped by a single major histocompatibility complex-peptide ligand in the presence of a single rearranged T cell receptor beta chain.
Fukui Y, Hashimoto O, Inayoshi A, Gyotoku T, Sano T, Koga T, Gushima T, Sasazuki T
J Exp Med. 1998
PubMed ID: 9730891
Regulation of major histocompatibility complex and TAP gene products in preimplantation mouse stage embryos.
Cooper JC, Fernandez N, Joly E, Dealtry GB
Am J Reprod Immunol. 1998
PubMed ID: 9764360
Role of CD8+ and CD4+ T cells in the rejection of murine intestinal allografts.
He G, Hart J, Thistlethwaite JR, Newell KA
Transplant Proc. 1998
PubMed ID: 9745505
Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands.
Ghendler Y, Teng MK, Liu JH, Witte T, Liu J, Kim KS, Kern P, Chang HC, Wang JH, Reinherz EL
Proc Natl Acad Sci U S A. 1998
PubMed ID: 9707600
Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1).
Miyazaki T, Lemonnier FA
J Exp Med. 1998
PubMed ID: 9705953
CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: beta 2-microglobulin-dependent and independent forms.
Amano M, Baumgarth N, Dick MD, Brossay L, Kronenberg M, Herzenberg LA, Strober S
J Immunol. 1998
PubMed ID: 9712035
Development of colonic adenocarcinomas in a mouse model of ulcerative colitis.
Shah SA, Simpson SJ, Brown LF, Comiskey M, de Jong YP, Allen D, Terhorst C
Inflamm Bowel Dis. 1998
PubMed ID: 9741021
The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition.
Achour A, Persson K, Harris RA, Sundbäck J, Sentman CL, Lindqvist Y, Schneider G, Kärre K
Immunity. 1998
PubMed ID: 9729040
Serum neopterin, beta2-microglobulin, soluble interleukin-2 receptors, and immunoglobulin levels in healthy adolescents.
Satoh T, Brown LM, Blattner WA, Maloney EM, Kurman CC, Nelson DL, Fuchs D, Wachter H, Tollerud DJ
Clin Immunol Immunopathol. 1998
PubMed ID: 9714695
Host NK cells are required for the growth of the human filarial parasite Brugia malayi in mice.
Babu S, Porte P, Klei TR, Shultz LD, Rajan TV
J Immunol. 1998
PubMed ID: 9686607
Expression screening of a yeast artificial chromosome contig refines the location of the mouse H3a minor histocompatibility antigen gene.
Zuberi AR, Christianson GJ, Dave SB, Bradley JA, Roopenian DC
J Immunol. 1998
PubMed ID: 9670959
Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes.
Smyth LA, Williams O, Huby RD, Norton T, Acuto O, Ley SC, Kioussis D
Proc Natl Acad Sci U S A. 1998
PubMed ID: 9653163
The mouse and human genes encoding the recognition component of the N-end rule pathway.
Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A
Proc Natl Acad Sci U S A. 1998
PubMed ID: 9653112
CD4+ and CD8+ T cell interactions in IFN-gamma and IL-4 responses to viral infections: requirements for IL-2.
Su HC, Cousens LP, Fast LD, Slifka MK, Bungiro RD, Ahmed R, Biron CA
J Immunol. 1998
PubMed ID: 9590250
Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.
O'Callaghan CA, Tormo J, Willcox BE, Blundell CD, Jakobsen BK, Stuart DI, McMichael AJ, Bell JI, Jones EY
Protein Sci. 1998
PubMed ID: 9605335
ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.
Lindquist JA, Jensen ON, Mann M, Hämmerling GJ
EMBO J. 1998
PubMed ID: 9545232
Adaptive response of iron absorption to anemia, increased erythropoiesis, iron deficiency, and iron loading in beta2-microglobulin knockout mice.
Santos M, Clevers H, de Sousa M, Marx JJ
Blood. 1998
PubMed ID: 9531620
Fine tuning of natural killer cell specificity and maintenance of self tolerance in MHC class I-deficient mice.
Salcedo M, Andersson M, Lemieux S, Van Kaer L, Chambers BJ, Ljunggren HG
Eur J Immunol. 1998
PubMed ID: 9565371
In vivo IL-4 responses to anti-IgD antibody are MHC class II dependent and beta 2-microglobulin independent and develop normally in the absence of IL-4 priming of T cells.
Morris SC, Coffman RL, Finkelman FD
J Immunol. 1998
PubMed ID: 9531287
Tissue-specific recognition of mouse CD1 molecules.
Park SH, Roark JH, Bendelac A
J Immunol. 1998
PubMed ID: 9531267
Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts.
Dandoy-Dron F, Guillo F, Benboudjema L, Deslys JP, Lasmézas C, Dormont D, Tovey MG, Dron M
J Biol Chem. 1998
PubMed ID: 9516475
Age-dependent appearance of NK1.1+ T cells in the livers of beta2-microglobulin knockout and SJL mice.
Murakami M, Paul WE
J Immunol. 1998
PubMed ID: 9510163
Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization.
Seymour BW, Gershwin LJ, Coffman RL
J Exp Med. 1998
PubMed ID: 9480982
The level of CD4 surface protein influences T cell selection in the thymus.
Frank GD, Parnes JR
J Immunol. 1998
PubMed ID: 9551897
Rejection of allogeneic and syngeneic but not MHC class I-deficient tumor grafts by MHC class I-deficient mice.
Freland S, Chambers BJ, Andersson M, Van Kaer L, Ljunggren HG
J Immunol. 1998
PubMed ID: 9551890
Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses.
Noble A, Zhao ZS, Cantor H
J Immunol. 1998
PubMed ID: 9551889
Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells.
Noble A, Pestano GA, Cantor H
J Immunol. 1998
PubMed ID: 9551888
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor.
Vaughn DE, Bjorkman PJ
Structure. 1998
PubMed ID: 9493268
Beta2-microglobulin-deficient NK cells show increased sensitivity to MHC class I-mediated inhibition, but self tolerance does not depend upon target cell expression of H-2Kb and Db heavy chains.
Höglund P, Glas R, Ménard C, Kåse A, Johansson MH, Franksson L, Lemmonier F, Kärre K
Eur J Immunol. 1998
PubMed ID: 9485216
A crucial role for B cells in neuroinvasive scrapie.
Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, Bluethmann H, Bootz F, Suter M, Zinkernagel RM, Aguzzi A
Nature. 1997
PubMed ID: 9414161
TAP peptide transporter-independent presentation of heat-killed Sendai virus antigen on MHC class I molecules by splenic antigen-presenting cells.
Liu T, Chambers B, Diehl AD, Van Kaer L, Jondal M, Ljunggren HG
J Immunol. 1997
PubMed ID: 9548476
The basis for self-tolerance of natural killer cells in beta2-microglobulin- and TAP-1- mice.
Dorfman JR, Zerrahn J, Coles MC, Raulet DH
J Immunol. 1997
PubMed ID: 9548460
Processing of exogenous hepatitis B surface antigen particles for Ld-restricted epitope presentation depends on exogenous beta2-microglobulin.
Schirmbeck R, Thoma S, Reimann J
Eur J Immunol. 1997
PubMed ID: 9464837
Beta 2-microglobulin-deficient mice are protected from hypergammaglobulinemia and have defective antibody responses because of increased IgG catabolism.
Christianson GJ, Brooks W, Vekasi S, Manolfi EA, Niles J, Roopenian SL, Roths JB, Rothlein R, Roopenian DC
J Immunol. 1997
PubMed ID: 9366402
CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway.
Lesage S, Steff AM, Philippoussis F, Pagé M, Trop S, Mateo V, Hugo P
J Immunol. 1997
PubMed ID: 9366400
Influenza infection of beta 2-microglobulin-deficient (beta 2m-/-) mice reveals a loss of CD4+ T cell functions with aging.
Taylor SF, Cottey RJ, Zander DS, Bender BS
J Immunol. 1997
PubMed ID: 9317144
Autoantibody production and cytokine profiles of MHC class I (beta2-microglobulin) gene deleted New Zealand black (NZB) mice.
Chen SY, Takeoka Y, Pike-Nobile L, Ansari AA, Boyd R, Gershwin ME
Clin Immunol Immunopathol. 1997
PubMed ID: 9281391
Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides.
Grubin CE, Kovats S, deRoos P, Rudensky AY
Immunity. 1997
PubMed ID: 9285405
Allospecific cytotoxic T cells generated from beta 2m-/- mice in primary MLC: analysis of activation requirements, specificity, and phenotype.
Lamousé-Smith E, McCarthy SA
Cell Immunol. 1997
PubMed ID: 9268494
Mouse CD1 is mainly expressed on hemopoietic-derived cells.
Brossay L, Jullien D, Cardell S, Sydora BC, Burdin N, Modlin RL, Kronenberg M
J Immunol. 1997
PubMed ID: 9233616
Humoral and cellular immunity in secondary infection due to murine Chlamydia trachomatis.
Williams DM, Grubbs BG, Pack E, Kelly K, Rank RG
Infect Immun. 1997
PubMed ID: 9199462
The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide.
Balendiran GK, Solheim JC, Young AC, Hansen TH, Nathenson SG, Sacchettini JC
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9192660
HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice.
Pascolo S, Bervas N, Ure JM, Smith AG, Lemonnier FA, Pérarnau B
J Exp Med. 1997
PubMed ID: 9182675
Uterine NK cells and trophoblast HLA class I molecules.
King A, Hiby SE, Verma S, Burrows T, Gardner L, Loke YW
Am J Reprod Immunol. 1997
PubMed ID: 9228302
Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection.
Soong L, Chang CH, Sun J, Longley BJ, Ruddle NH, Flavell RA, McMahon-Pratt D
J Immunol. 1997
PubMed ID: 9164958
Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice.
Christianson SW, Greiner DL, Hesselton RA, Leif JH, Wagar EJ, Schweitzer IB, Rajan TV, Gott B, Roopenian DC, Shultz LD
J Immunol. 1997
PubMed ID: 9103418
Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice.
Salcedo M, Diehl AD, Olsson-Alheim MY, Sundbäck J, Van Kaer L, Kärre K, Ljunggren HG
J Immunol. 1997
PubMed ID: 9120271
Large-scale concatenation cDNA sequencing.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA
Genome Res. 1997
PubMed ID: 9110174
T cell-mediated elimination of B7.2 transgenic B cells.
Fournier S, Rathmell JC, Goodnow CC, Allison JP
Immunity. 1997
PubMed ID: 9075933
CD2 regulates the positive selection and function of antigen-specific CD4- CD8+ T cells.
Teh SJ, Killeen N, Tarakhovsky A, Littman DR, Teh HS
Blood. 1997
PubMed ID: 9028954
T helper subset differentiation in the absence of invariant chain.
Brown DR, Swier K, Moskowitz NH, Naujokas MF, Locksley RM, Reiner SL
J Exp Med. 1997
PubMed ID: 8996239
The role of MHC class I heterodimer expression in mouse ankylosing enthesopathy.
Weinreich SS, Hoebe-Hewryk B, van der Horst AR, Boog CJ, Ivanyi P
Immunogenetics. 1997
PubMed ID: 9148786
Requirement of IL-7 for IL-4-producing potential of MHC class I-selected CD4-CD8-TCR alpha beta+ thymocytes.
Leite-de-Moraes MC, Herbelin A, Gombert JM, Vicari A, Papiernik M, Dy M
Int Immunol. 1997
PubMed ID: 9043949
Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in TgE26 mice.
Guimond MJ, Luross JA, Wang B, Terhorst C, Danial S, Croy BA
Biol Reprod. 1997
PubMed ID: 9002646
Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn.
Israel EJ, Wilsker DF, Hayes KC, Schoenfeld D, Simister NE
Immunology. 1996
PubMed ID: 9014824
Lupus nephritis in the absence of renal major histocompatibility complex class I and class II molecules.
Mukherjee R, Zhang Z, Zhong R, Yin ZQ, Roopenian DC, Jevnikar AM
J Am Soc Nephrol. 1996
PubMed ID: 8959638
Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.
Santos M, Schilham MW, Rademakers LH, Marx JJ, de Sousa M, Clevers H
J Exp Med. 1996
PubMed ID: 8920884
Altered kinetics of CD4+ T cell proliferation and interferon-gamma production in the absence of CD8+ T lymphocytes in virus-infected beta2-microglobulin-deficient mice.
Vikingsson A, Pederson K, Muller D
Cell Immunol. 1996
PubMed ID: 8912885
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages.
Robey E, Chang D, Itano A, Cado D, Alexander H, Lans D, Weinmaster G, Salmon P
Cell. 1996
PubMed ID: 8898201
Natural killer cell recognition of "self" and "non-self" triggering antigens on normal lymphoblasts.
Hirayama M, Genyea C, Kaplan J
Cell Immunol. 1996
PubMed ID: 8871599
Expansion of natural (NK1+) T cells that express alpha beta T cell receptors in transporters associated with antigen presentation-1 null and thymus leukemia antigen positive mice.
Joyce S, Negishi I, Boesteanu A, DeSilva AD, Sharma P, Chorney MJ, Loh DY, Van Kaer L
J Exp Med. 1996
PubMed ID: 8879233
Beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses.
Zhang Y, Rogers KH, Lewis DB
J Exp Med. 1996
PubMed ID: 8879221
The Cdc25 genes map to mouse chromosomes 2, 9, and 18.
Lock LF, Wickramasinghe D, Ernst MK, Gilbert DJ, Copeland NG, Jenkins NA, Donovan PJ
Mamm Genome. 1996
PubMed ID: 8854867
Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.
Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD
Cell Immunol. 1996
PubMed ID: 8806787
Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.
Sadasivan B, Lehner PJ, Ortmann B, Spies T, Cresswell P
Immunity. 1996
PubMed ID: 8769474
Infection of class II-deficient mice by the DA strain of Theiler's virus.
Fiette L, Brahic M, Pena-Rossi C
J Virol. 1996
PubMed ID: 8676513
beta2-microglobulin dependence of the lupus-like autoimmune syndrome of MRL-lpr mice.
Christianson GJ, Blankenburg RL, Duffy TM, Panka D, Roths JB, Marshak-Rothstein A, Roopenian DC
J Immunol. 1996
PubMed ID: 8648144
The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor.
Junghans RP, Anderson CL
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8643606
Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk.
Liao X, Zhou R, Gilbert DJ, Copeland NG, Jenkins NA
Mamm Genome. 1996
PubMed ID: 8661736
Development of CD8 alpha alpha+ intestinal intraepithelial T cells in beta 2-microglobulin- and/or TAP1-deficient mice.
Fujiura Y, Kawaguchi M, Kondo Y, Obana S, Yamamoto H, Nanno M, Ishikawa H
J Immunol. 1996
PubMed ID: 8609387
A "double adaptor" method for improved shotgun library construction.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA
Anal Biochem. 1996
PubMed ID: 8619474
A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.
Zuberi AR, Nguyen HQ, Auman HJ, Taylor BA, Roopenian DC
Genomics. 1996
PubMed ID: 8617512
Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Smith KJ, Reid SW, Harlos K, McMichael AJ, Stuart DI, Bell JI, Jones EY
Immunity. 1996
PubMed ID: 8624812
Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice.
Ghetie V, Hubbard JG, Kim JK, Tsen MF, Lee Y, Ward ES
Eur J Immunol. 1996
PubMed ID: 8605939
beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism.
Rothenberg BE, Voland JR
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8643666
Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice.
Guery JC, Galbiati F, Smiroldo S, Adorini L
J Exp Med. 1996
PubMed ID: 8627161
Acceptance of skin grafts between mice bearing different allelic forms of beta 2-microglobulin.
Hederer RA, Chandler PR, Dyson PJ, Antoniou AN, Millrain MM, Mellor AL, Simpson E, Robinson PJ
Transplantation. 1996
PubMed ID: 8600640
Genetic composition of the recombinant congenic strains.
Stassen AP, Groot PC, Eppig JT, Demant P
Mamm Genome. 1996
PubMed ID: 8903730
CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice.
Dalloul AH, Ngo K, Fung-Leung WP
Eur J Immunol. 1996
PubMed ID: 8566069
Bone turnover in homozygous beta 2-microglobulin knock-out mice does not differ from that of their heterozygous littermates.
Marusić A, Katavić V, Stimac D, Kusec V, Jonjić S
Eur J Clin Chem Clin Biochem. 1995
PubMed ID: 8845422
Natural killer cell activity in lymphocytic choriomeningitis virus-infected beta 2-microglobulin-deficient mice.
Zajac AJ, Muller D, Pederson K, Frelinger JA, Quinn DG
Int Immunol. 1995
PubMed ID: 8562499
Spontaneous inflammatory arthritis in HLA-B27 transgenic mice lacking beta 2-microglobulin: a model of human spondyloarthropathies.
Khare SD, Luthra HS, David CS
J Exp Med. 1995
PubMed ID: 7561688
Oestrogen influences CD4+ T-lymphocyte activity in vivo and in vitro in beta 2-microglobulin-deficient mice.
Muller D, Chen M, Vikingsson A, Hildeman D, Pederson K
Immunology. 1995
PubMed ID: 7490113
Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis.
Simpson SJ, Mizoguchi E, Allen D, Bhan AK, Terhorst C
Eur J Immunol. 1995
PubMed ID: 7589135
beta 2-Microglobulin in transplantation.
Zeff RA
Transplantation. 1995
PubMed ID: 7645032
Control of thymus-independent intestinal intraepithelial lymphocytes by beta 2-microglobulin.
Neuhaus O, Emoto M, Blum C, Yamamoto S, Kaufmann SH
Eur J Immunol. 1995
PubMed ID: 7664795
Increased number of CD4-CD8+ MHC class II-specific T cells in MHC class II-deficient mice.
Marusić-Galesić S, Walden P
Immunology. 1995
PubMed ID: 7558133
Evidence for lineage commitment and initiation of positive selection by thymocytes with intermediate surface phenotypes.
van Meerwijk JP, O'Connell EM, Germain RN
J Immunol. 1995
PubMed ID: 7759870
Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.
Kozak CA, Adamson MC, Buckler CE, Segovia L, Paralkar V, Wistow G
Genomics. 1995
PubMed ID: 7558020
Increased gamma-delta T-lymphocyte response to Mycobacterium bovis BCG in major histocompatibility complex class I-deficient mice.
Muller D, Pakpreo P, Filla J, Pederson K, Cigel F, Malkovska V
Infect Immun. 1995
PubMed ID: 7768622
The interaction of beta 2-microglobulin (beta 2m) with mouse class I major histocompatibility antigens and its ability to support peptide binding. A comparison of human and mouse beta 2m.
Pedersen LO, Stryhn A, Holter TL, Etzerodt M, Gerwien J, Nissen MH, Thøgersen HC, Buus S
Eur J Immunol. 1995
PubMed ID: 7614989
MHC class I expression and CD8+ T cell development in TAP1/beta 2-microglobulin double mutant mice.
Ljunggren HG, Van Kaer L, Sabatine MS, Auchincloss H, Tonegawa S, Ploegh HL
Int Immunol. 1995
PubMed ID: 7577806
Identification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein gene.
Haas S, Steplewski A, Siracusa LD, Amini S, Khalili K
J Biol Chem. 1995
PubMed ID: 7539003
Amino acid sequence of a modified beta 2-microglobulin in renal failure patient urine and long-term dialysis patient blood.
Momoi T, Suzuki M, Titani K, Hisanaga S, Ogawa H, Saito A
Clin Chim Acta. 1995
PubMed ID: 7554280
Ly-49-independent natural killer (NK) cell specificity revealed by NK cell clones derived from p53-deficient mice.
Karlhofer FM, Orihuela MM, Yokoyama WM
J Exp Med. 1995
PubMed ID: 7722455
Presensitization by skin grafting from major histocompatibility complex class I or major histocompatibility complex class II deficient mice identifies class I antigens as inducers of allosensitization.
Qian S, Fu F, Li Y, Gao L, Lu L, Noyola H, Rao AS, Thomson AW, Fung JJ
Immunology. 1995
PubMed ID: 7635525
Surface expression of beta 2-microglobulin-associated thymus-leukemia antigen is independent of TAP2.
Rodgers JR, Mehta V, Cook RG
Eur J Immunol. 1995
PubMed ID: 7737270
A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.
Chiannilkulchai N, Pasturaud P, Richard I, Auffray C, Beckmann JS
Hum Mol Genet. 1995
PubMed ID: 7633422
Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8+ T cells.
Gombold JL, Sutherland RM, Lavi E, Paterson Y, Weiss SR
Microb Pathog. 1995
PubMed ID: 7565015
The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Collins EJ, Garboczi DN, Karpusas MN, Wiley DC
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7862664
Immune response to Mycobacterium bovis bacille Calmette Guérin infection in major histocompatibility complex class I- and II-deficient knock-out mice: contribution of CD4 and CD8 T cells to acquired resistance.
Ladel CH, Daugelat S, Kaufmann SH
Eur J Immunol. 1995
PubMed ID: 7875199
Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I.
Maldonado MA, Eisenberg RA, Roper E, Cohen PL, Kotzin BL
J Exp Med. 1995
PubMed ID: 7530760
NK cell response to viral infections in beta 2-microglobulin-deficient mice.
Tay CH, Welsh RM, Brutkiewicz RR
J Immunol. 1995
PubMed ID: 7529286
Induction of peptide-specific CD8+ CTL clones in beta 2-microglobulin-deficient mice.
Cook JR, Solheim JC, Connolly JM, Hansen TH
J Immunol. 1995
PubMed ID: 7995959
Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice.
Ljunggren HG, Van Kaer L, Ashton-Rickardt PG, Tonegawa S, Ploegh HL
Eur J Immunol. 1995
PubMed ID: 7843229
Heterotransplantation of primary and established human tumour cells in nude mice.
Noël A, Borcy V, Bracke M, Gilles C, Bernard J, Birembaut P, Mareel M, Foidart JM
Anticancer Res. 1995
PubMed ID: 7733618
Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice.
Aiuti A, Forte P, Simeoni L, Lino M, Pozzi L, Fattorossi A, Giacomini P, Ginelli E, Beretta A, Siccardi A
Immunogenetics. 1995
PubMed ID: 7590970
IL-2-dependent NK cell responses discovered in virus-infected beta 2-microglobulin-deficient mice.
Su HC, Orange JS, Fast LD, Chan AT, Simpson SJ, Terhorst C, Biron CA
J Immunol. 1994
PubMed ID: 7989765
Crystal structure of the complex of rat neonatal Fc receptor with Fc.
Burmeister WP, Huber AH, Bjorkman PJ
Nature. 1994
PubMed ID: 7969498
The ubiquitous mitochondrial creatine kinase gene maps to a conserved region on human chromosome 15q15 and mouse chromosome 2 bands F1-F3.
Steeghs K, Merkx G, Wieringa B
Genomics. 1994
PubMed ID: 7896282
Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.
Goldstein C, Liaw P, Jimenez SA, Buchberg AM, Siracusa LD
Mamm Genome. 1994
PubMed ID: 7873879
Intracisternal A-type particle elements as genetic markers: detection by repeat element viral element amplified locus-PCR.
Kaushik N, Stoye JP
Mamm Genome. 1994
PubMed ID: 7873878
CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse.
Blair PJ, Bultman SJ, Haas JC, Rouse BT, Wilkinson JE, Godfrey VL
J Immunol. 1994
PubMed ID: 7930593
Thymic development in human CD4 transgenic mice. Positive selection occurs after commitment to the CD8 lineage.
Paterson RK, Burkly LC, Kurahara DK, Dunlap A, Flavell RA, Finkel TH
J Immunol. 1994
PubMed ID: 7930572
Mouse prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA-transfected Chinese hamster ovary cells.
Irie A, Segi E, Sugimoto Y, Ichikawa A, Negishi M
Biochem Biophys Res Commun. 1994
PubMed ID: 7945376
Glycation of human beta 2-microglobulin in patients with hemodialysis-associated amyloidosis: identification of the glycated sites.
Miyata T, Inagi R, Wada Y, Ueda Y, Iida Y, Takahashi M, Taniguchi N, Maeda K
Biochemistry. 1994
PubMed ID: 7918443
CD4+ and CD8+ alpha beta, and gamma delta T cells are cytotoxic effector cells of beta 2-microglobulin-deficient mice against cells having normal MHC class I expression.
Udaka K, Marusić-Galesić S, Walden P
J Immunol. 1994
PubMed ID: 7915743
The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression.
Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K
Gene. 1994
PubMed ID: 8076819
Molecular and genetic characterization of GABP beta.
de la Brousse FC, Birkenmeier EH, King DS, Rowe LB, McKnight SL
Genes Dev. 1994
PubMed ID: 7958862
Temporal and spatial expression of major histocompatibility complex class I H-2K in the early mouse embryo.
Arcellana-Panlilio MY, Schultz GA
Biol Reprod. 1994
PubMed ID: 7948472
MHC class I molecule-restricted presentation of viral antigen in beta 2-microglobulin-deficient mice.
Lehmann-Grube F, Dralle H, Utermöhlen O, Löhler J
J Immunol. 1994
PubMed ID: 8021497
Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice.
Aldrich CJ, Ljunggren HG, Van Kaer L, Ashton-Rickardt PG, Tonegawa S, Forman J
Proc Natl Acad Sci U S A. 1994
PubMed ID: 8022816
Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes.
Coles MC, Raulet DH
J Exp Med. 1994
PubMed ID: 8006596
Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor.
Kirberg J, Baron A, Jakob S, Rolink A, Karjalainen K, von Boehmer H
J Exp Med. 1994
PubMed ID: 8006585
Tight-skin (Tsk) maps on mouse chromosome 2 within the region of linkage homology with human chromosome 15.
Douté RC, Clark SH
Genomics. 1994
PubMed ID: 7959775
Reduced beta 2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme.
Larsson S, Hotchkiss G, Andäng M, Nyholm T, Inzunza J, Jansson I, Ahrlund-Richter L
Nucleic Acids Res. 1994
PubMed ID: 8036151
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points.
Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ
Immunity. 1994
PubMed ID: 7889408
Pro-T cells in fetal thymus express c-kit and RAG-2 but do not rearrange the gene encoding the T cell receptor beta chain.
Hozumi K, Kobori A, Sato T, Nozaki H, Nishikawa S, Nishimura T, Habu S
Eur J Immunol. 1994
PubMed ID: 7515811
Endogenous nonecotropic proviruses mapped with oligonucleotide probes from the long terminal repeat region.
Frankel WN, Coffin JM
Mamm Genome. 1994
PubMed ID: 8075500
T-cell development and function in gene-knockout mice.
Yeung RS, Penninger J, Mak TW
Curr Opin Immunol. 1994
PubMed ID: 8011213
Assignment of two alpha 2 adrenoceptor subtype genes to murine chromosomes.
Chang NC, Jenkins NA, Gilbert DJ, Copeland NG, Chang YH, Chen WM, Chang AC
Neurosci Lett. 1994
PubMed ID: 8177505
The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I.
Glas R, Ohlén C, Höglund P, Kärre K
J Exp Med. 1994
PubMed ID: 8294874
Antigen presentation by non-classical class I molecules.
Stroynowski I, Lindahl KF
Curr Opin Immunol. 1994
PubMed ID: 8172679
Iron overload in beta 2-microglobulin-deficient mice.
de Sousa M, Reimão R, Lacerda R, Hugo P, Kaufmann SH, Porto G
Immunol Lett. 1994
PubMed ID: 8013958
Gene mapping in a murine cell line by immunoselection with cytotoxic T lymphocytes.
Zuberi AR, Dudley ME, Christianson GJ, Roopenian DC
Genomics. 1994
PubMed ID: 7514566
The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection.
Young AC, Zhang W, Sacchettini JC, Nathenson SG
Cell. 1994
PubMed ID: 7506996
Continued mapping of chromosome 2 genes.
Graff RJ, Hauptfeld V, Riordan K, Kurtz M
Immunogenetics. 1994
PubMed ID: 8206522
The tight-skin (Tsk) mutation is closely linked to B2m on mouse chromosome 2.
Everett ET, Pablos JL, Harris SE, LeRoy EC, Norris JS
Mamm Genome. 1994
PubMed ID: 8111131
Isolation of a granulocyte inhibitory protein from uraemic patients with homology of beta 2-microglobulin.
Haag-Weber M, Mai B, Hörl WH
Nephrol Dial Transplant. 1994
PubMed ID: 8084451
Increased number of cytotoxic T cells within CD4+8- T cells in beta 2-microglobulin, major histocompatibility complex class I-deficient mice.
Marusić-Galesić S, Udaka K, Walden P
Eur J Immunol. 1993
PubMed ID: 8258325
Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages.
Crump AL, Grusby MJ, Glimcher LH, Cantor H
Proc Natl Acad Sci U S A. 1993
PubMed ID: 7902569
Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors.
Wilkie TM, Chen Y, Gilbert DJ, Moore KJ, Yu L, Simon MI, Copeland NG, Jenkins NA
Genomics. 1993
PubMed ID: 8288218
The tight skin (Tsk) mutation in the mouse, a model for human fibrotic diseases, is tightly linked to the beta 2-microglobulin (B2m) gene on chromosome 2.
Siracusa LD, Christner P, McGrath R, Mowers SD, Nelson KK, Jimenez SA
Genomics. 1993
PubMed ID: 7902327
Development of mature CD8+ thymocytes: selection rather than instruction?
van Meerwijk JP, Germain RN
Science. 1993
PubMed ID: 8102208
Genetically modified animals and immunodeficiency.
Yeung RS, Penninger J, Mak TW
Curr Opin Immunol. 1993
PubMed ID: 8105804
Course of Leishmania infection in beta 2-microglobulin-deficient mice.
Overath P, Harbecke D
Immunol Lett. 1993
PubMed ID: 7901152
Mice lacking major histocompatibility complex class I and class II molecules.
Grusby MJ, Auchincloss H, Lee R, Johnson RS, Spencer JP, Zijlstra M, Jaenisch R, Papaioannou VE, Glimcher LH
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8483910
Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture.
Hogquist KA, Gavin MA, Bevan MJ
J Exp Med. 1993
PubMed ID: 8478616
The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock.
Taylor BA, Rowe L, Grieco DA
Genomics. 1993
PubMed ID: 8390965
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.
Davis CB, Killeen N, Crooks ME, Raulet D, Littman DR
Cell. 1993
PubMed ID: 8097431
Another view of the selective model of thymocyte selection.
Chan SH, Cosgrove D, Waltzinger C, Benoist C, Mathis D
Cell. 1993
PubMed ID: 8097430
Highly lytic CD8+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin, MHC class I-deficient mice.
Apasov S, Sitkovsky M
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8464897
Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse.
Carlson GA, Ebeling C, Torchia M, Westaway D, Prusiner SB
Genetics. 1993
PubMed ID: 8462855
Lack of HLA class I antigen expression by melanoma cells SK-MEL-33 caused by a reading frameshift in beta 2-microglobulin messenger RNA.
Wang Z, Cao Y, Albino AP, Zeff RA, Houghton A, Ferrone S
J Clin Invest. 1993
PubMed ID: 8432869
The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.
Malek TR, Vincek V, Gatalica B, Bucan M
Immunogenetics. 1993
PubMed ID: 8482578
Sequence divergence of B2m alleles of wild Mus musculus and Mus spretus implies positive selection.
Hermel E, Robinson PJ, She JX, Lindahl KF
Immunogenetics. 1993
PubMed ID: 8482575
The pituitary hormones arginine vasopressin-neurophysin II and oxytocin-neurophysin I show close linkage with interleukin-1 on mouse chromosome 2.
Marini JC, Nelson KK, Battey J, Siracusa LD
Genomics. 1993
PubMed ID: 8432536
Theiler's virus infection of beta 2-microglobulin-deficient mice.
Fiette L, Aubert C, Brahic M, Rossi CP
J Virol. 1993
PubMed ID: 8416386
Antiviral immune responses of lymphocytic choriomeningitis virus-infected mice lacking CD8+ T lymphocytes because of disruption of the beta 2-microglobulin gene.
Lehmann-Grube F, Löhler J, Utermöhlen O, Gegin C
J Virol. 1993
PubMed ID: 8093219
Assembly-dependent expression of antigenic epitopes by beta 2-microglobulin(b).
Tatake RJ, Zeff RA
Immunogenetics. 1993
PubMed ID: 7688348
Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.
Flynn JL, Goldstein MM, Triebold KJ, Koller B, Bloom BR
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1465432
Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Guo HC, Jardetzky TS, Garrett TP, Lane WS, Strominger JL, Wiley DC
Nature. 1992
PubMed ID: 1448153
1H NMR assignments and secondary structure of human beta 2-microglobulin in solution.
Okon M, Bray P, Vucelić D
Biochemistry. 1992
PubMed ID: 1390678
The murine pallid mutation is a platelet storage pool disease associated with the protein 4.2 (pallidin) gene.
White RA, Peters LL, Adkison LR, Korsgren C, Cohen CM, Lux SE
Nat Genet. 1992
PubMed ID: 1284644
Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.
Hou S, Doherty PC, Zijlstra M, Jaenisch R, Katz JM
J Immunol. 1992
PubMed ID: 1354233
Expression of TAPA-1 in preimplantation mouse embryos.
Andria ML, Barsh GS, Levy S
Biochem Biophys Res Commun. 1992
PubMed ID: 1380797
Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.
Fremont DH, Matsumura M, Stura EA, Peterson PA, Wilson IA
Science. 1992
PubMed ID: 1323877
Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses.
Spriggs MK, Koller BH, Sato T, Morrissey PJ, Fanslow WC, Smithies O, Voice RF, Widmer MB, Maliszewski CR
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1631092
Damage in B2m genes and DNA methylation of H-2 genes are involved in loss of expression of class I MHC products on the membrane of LR.4, a cell line derivative of the T-cell lymphoma L5178Y.
Nava G, Ocadiz R, Ortega V, Alfaro G
Eur J Immunogenet. 1992
PubMed ID: 1627535
Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones.
Yasue M, Serikawa T, Kuramoto T, Mori M, Higashiguchi T, Ishizaki K, Yamada J
Genomics. 1992
PubMed ID: 1572638
Skin graft rejection by beta 2-microglobulin-deficient mice.
Zijlstra M, Auchincloss H, Loring JM, Chase CM, Russell PS, Jaenisch R
J Exp Med. 1992
PubMed ID: 1552287
Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge.
Bender BS, Croghan T, Zhang L, Small PA
J Exp Med. 1992
PubMed ID: 1552285
Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection.
Tarleton RL, Koller BH, Latour A, Postan M
Nature. 1992
PubMed ID: 1549177
LCMV-specific, class II-restricted cytotoxic T cells in beta 2-microglobulin-deficient mice.
Muller D, Koller BH, Whitton JL, LaPan KE, Brigman KK, Frelinger JA
Science. 1992
PubMed ID: 1347959
Beta 2-microglobulin gene is mutated in a human colon cancer cell line (HCT) deficient in the expression of HLA class I antigens on the cell surface.
Gattoni-Celli S, Kirsch K, Timpane R, Isselbacher KJ
Cancer Res. 1992
PubMed ID: 1737380
Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2.
Moen CJ, Snoek M, Hart AA, Demant P
Oncogene. 1992
PubMed ID: 1347918
Ham-2 corrects the class I antigen-processing defect in RMA-S cells.
Attaya M, Jameson S, Martinez CK, Hermel E, Aldrich C, Forman J, Lindahl KF, Bevan MJ, Monaco JJ
Nature. 1992
PubMed ID: 1538753
Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice.
Correa I, Bix M, Liao NS, Zijlstra M, Jaenisch R, Raulet D
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1346234
Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses.
McAleer MA, Aitman TJ, Cornall RJ, Ghosh S, Hall JR, Hearne CM, Love JM, Prins JB, Ramachandran S, Rodrigues N
Mamm Genome. 1992
PubMed ID: 1643308
Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice.
Pereira P, Zijlstra M, McMaster J, Loring JM, Jaenisch R, Tonegawa S
EMBO J. 1992
PubMed ID: 1531458
Biochemical characterization of serum and urinary beta 2 microglobulin in end-stage renal disease patients.
Argilés A, Derancourt J, Jauregui-Adell J, Mion C, Demaille JG
Nephrol Dial Transplant. 1992
PubMed ID: 1336137
cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence.
Nelson PA, Lippke JA, Murcko MA, Rosborough SL, Peattie DA
Gene. 1991
PubMed ID: 1722474
Characterization of the murine thrombospondin gene.
Lawler J, Duquette M, Ferro P, Copeland NG, Gilbert DJ, Jenkins NA
Genomics. 1991
PubMed ID: 1774063
Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells.
Eichelberger M, Allan W, Zijlstra M, Jaenisch R, Doherty PC
J Exp Med. 1991
PubMed ID: 1919440
Requirement for positive selection of gamma delta receptor-bearing T cells.
Wells FB, Gahm SJ, Hedrick SM, Bluestone JA, Dent A, Matis LA
Science. 1991
PubMed ID: 1831565
Interspecific backcross mice show sex-specific differences in allelic inheritance.
Siracusa LD, Alvord WG, Bickmore WA, Jenkins NA, Copeland NG
Genetics. 1991
PubMed ID: 1916246
The mouse homolog of the Gibbon ape leukemia virus receptor: genetic mapping and a possible receptor function in rodents.
Adamson MC, Silver J, Kozak CA
Virology. 1991
PubMed ID: 1649508
Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution.
Saper MA, Bjorkman PJ, Wiley DC
J Mol Biol. 1991
PubMed ID: 2038058
Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice.
Bix M, Liao NS, Zijlstra M, Loring J, Jaenisch R, Raulet D
Nature. 1991
PubMed ID: 1987491
Additional mapping of mouse chromosome 2 genes.
Graff RJ, Kurtz ME, Paul R, Martin D, Roopenian DC
Immunogenetics. 1991
PubMed ID: 1999355
Ras-like genes and gene families in the mouse.
Drivas G, Massey R, Chang HY, Rush MG, D'Eustachio P
Mamm Genome. 1991
PubMed ID: 1686838
Tumor necrosis factor, interleukin-1 and beta 2-microglobulin levels in chronic hemodialysis patients.
Caruana RJ, Lobel SA, Leffell MS, Campbell H, Cheek PL
Int J Artif Organs. 1990
PubMed ID: 2289831
A mouse model of the aniridia-Wilms tumor deletion syndrome.
Glaser T, Lane J, Housman D
Science. 1990
PubMed ID: 2173141
Rate and mechanism of generation of beta 2-microglobulin mutants from a heterozygous murine cell line.
Rajan TV, Moffat LF, Frankel WN
J Immunol. 1990
PubMed ID: 2200825
Staggerer mutant mouse Purkinje cells do not contain detectable calmodulin mRNA.
Messer A, Plummer-Siegard J, Eisenberg B
J Neurochem. 1990
PubMed ID: 2355223
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
Koller BH, Marrack P, Kappler JW, Smithies O
Science. 1990
PubMed ID: 2112266
Location of the gene involving the small eye mutation on mouse chromosome 2 suggests homology with human aniridia 2 (AN2).
van der Meer-de Jong R, Dickinson ME, Woychik RP, Stubbs L, Hetherington C, Hogan BL
Genomics. 1990
PubMed ID: 2347591
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.
Zijlstra M, Bix M, Simister NE, Loring JM, Raulet DH, Jaenisch R
Nature. 1990
PubMed ID: 2139497
The HOX-5 and surfeit gene clusters are linked in the proximal portion of mouse chromosome 2.
Stubbs L, Huxley C, Hogan B, Evans T, Fried M, Duboule D, Lehrach H
Genomics. 1990
PubMed ID: 1971250
Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.
Dickinson ME, Kobrin MS, Silan CM, Kingsley DM, Justice MJ, Miller DA, Ceci JD, Lock LF, Lee A, Buchberg AM
Genomics. 1990
PubMed ID: 1970330
A molecular genetic linkage map of mouse chromosome 2.
Siracusa LD, Silan CM, Justice MJ, Mercer JA, Bauskin AR, Ben-Neriah Y, Duboule D, Hastie ND, Copeland NG, Jenkins NA
Genomics. 1990
PubMed ID: 1970329
Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.
Joseph DR, Sullivan PM, Wang YM, Kozak C, Fenstermacher DA, Behrendsen ME, Zahnow CA
Proc Natl Acad Sci U S A. 1990
PubMed ID: 2300558
Sequences homologous to glutamic acid decarboxylase cDNA are present on mouse chromosomes 2 and 10.
Brilliant MH, Szabo G, Katarova Z, Kozak CA, Glaser TM, Greenspan RJ, Housman DE
Genomics. 1990
PubMed ID: 1968040
The cDNA structure and expression analysis of the genes for the cysteine proteinase inhibitor cystatin C and for beta 2-microglobulin in rat brain.
Cole T, Dickson PW, Esnard F, Averill S, Risbridger GP, Gauthier F, Schreiber G
Eur J Biochem. 1989
PubMed ID: 2689174
Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells.
Zijlstra M, Li E, Sajjadi F, Subramani S, Jaenisch R
Nature. 1989
PubMed ID: 2685607
Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.
Koller BH, Smithies O
Proc Natl Acad Sci U S A. 1989
PubMed ID: 2682666
Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.
Glaser T, Matthews KE, Hudson JW, Seth P, Housman DE, Crerar MM
Genomics. 1989
PubMed ID: 2575583
Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.
Siracusa LD, Buchberg AM, Copeland NG, Jenkins NA
Genetics. 1989
PubMed ID: 2759422
The cardiac actin locus (Actc-1) is not on mouse chromosome 17 but is linked to beta 2-microglobulin on chromosome 2.
Crosby JL, Phillips SJ, Nadeau JH
Genomics. 1989
PubMed ID: 2570027
An Fc receptor structurally related to MHC class I antigens.
Simister NE, Mostov KE
Nature. 1989
PubMed ID: 2911353
Collagen-binding affinity of beta-2-microglobulin, a preprotein of hemodialysis-associated amyloidosis.
Homma N, Gejyo F, Isemura M, Arakawa M
Nephron. 1989
PubMed ID: 2674742
Responses against antigens encoded by the H-3 histocompatibility locus: antigens stimulating class I MHC- and class II MHC-restricted T cells are encoded by separate genes.
Roopenian DC, Davis AP
Immunogenetics. 1989
PubMed ID: 2530167
The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters.
Brodeur PH, Osman GE, Mackle JJ, Lalor TM
J Exp Med. 1988
PubMed ID: 3199068
Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time.
Carlson GA, Goodman PA, Lovett M, Taylor BA, Marshall ST, Peterson-Torchia M, Westaway D, Prusiner SB
Mol Cell Biol. 1988
PubMed ID: 3149717
undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1.
Balling R, Deutsch U, Gruss P
Cell. 1988
PubMed ID: 3180219
Chromosomal location of three spectrin genes: relationship to the inherited hemolytic anemias of mouse and man.
Birkenmeier CS, McFarland-Starr EC, Barker JE
Proc Natl Acad Sci U S A. 1988
PubMed ID: 3186715
Correlation of beta-2-microglobulin concentration changes to changes of distribution volume.
Hönig R, Marsen T, Schad S, Barth C, Pollok M, Baldamus CA
Int J Artif Organs. 1988
PubMed ID: 3060434
Tissue-specific and cell surface expression of human major histocompatibility complex class I heavy (HLA-B7) and light (beta 2-microglobulin) chain genes in transgenic mice.
Chamberlain JW, Nolan JA, Conrad PJ, Vasavada HA, Vasavada HH, Ploegh HL, Ganguly S, Janeway CA, Weissman SM
Proc Natl Acad Sci U S A. 1988
PubMed ID: 2459712
Specific associations of fluorescent beta-2-microglobulin with cell surfaces. The affinity of different H-2 and HLA antigens for beta-2-microglobulin.
Hochman JH, Shimizu Y, DeMars R, Edidin M
J Immunol. 1988
PubMed ID: 2450918
In vitro production of beta 2 microglobulin by human myeloma cells.
Bataille R, Grenier J, Commes T
Cancer Invest. 1988
PubMed ID: 3048575
The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit.
Güssow D, Rein R, Ginjaar I, Hochstenbach F, Seemann G, Kottman A, Ploegh HL
J Immunol. 1987
PubMed ID: 3312414
Structure of the human class I histocompatibility antigen, HLA-A2.
Bjorkman PJ, Saper MA, Samraoui B, Bennett WS, Strominger JL, Wiley DC
Nature. 1987
PubMed ID: 3309677
Nucleotide sequence of rat beta 2-microglobulin cDNA.
Mauxion F, Kress M
Nucleic Acids Res. 1987
PubMed ID: 3309895
Localization of the inosine triphosphatase locus (Itp) on chromosome 2 of the mouse.
Taylor BA, Walls DM, Wimsatt MJ
Biochem Genet. 1987
PubMed ID: 3038074
Spontaneous deletion at the B2m locus: evidence for site-specific genetic rearrangement.
Potter TA, Frankel W, Zeff RA, Rajan TV
J Immunol. 1987
PubMed ID: 3543125
Genetic and biochemical characterization of antigens encoded by the Ly-24 (Pgp-1) locus.
Sutton VR, Wijffels GL, Walker ID, Hogarth PM, McKenzie IF
J Immunogenet. 1987
PubMed ID: 2443580
Multiplicity of chromosome 2 histocompatibility genes: new loci, H-44 and H-45.
Graff RJ, Martin-Morgan D, Kurtz ME
Immunogenetics. 1987
PubMed ID: 3301647
Interleukin-1 alpha and beta genes: linkage on chromosome 2 in the mouse.
D'Eustachio P, Jadidi S, Fuhlbrigge RC, Gray PW, Chaplin DD
Immunogenetics. 1987
PubMed ID: 2889668
Mapping of the mouse Ly-6, Xp-14, and Gdc-1 loci to chromosome 15.
Hogarth PM, McKenzie IF, Sutton VR, Curnow KM, Lee BK, Eicher EM
Immunogenetics. 1987
PubMed ID: 2880797
Polymerization of intact beta 2-microglobulin in tissue causes amyloidosis in patients on chronic hemodialysis.
Gorevic PD, Munoz PC, Casey TT, DiRaimondo CR, Stone WJ, Prelli FC, Rodrigues MM, Poulik MD, Frangione B
Proc Natl Acad Sci U S A. 1986
PubMed ID: 3532124
Genetic variation in the shape of the mouse mandible and its relationship to glucocorticoid-induced cleft palate analyzed by using recombinant inbred lines.
Lovell DP, Erickson RP
Genetics. 1986
PubMed ID: 3732791
Detection of a serum class I molecule in rat with anti-rat liver beta-2-microglobulin.
Matsumoto K, Natori T, Agui T, Tsutimoto S, Matsuhashi A, Gasser DL
Biochem Genet. 1986
PubMed ID: 3516141
Detailed analysis of the mouse H-2Kb promoter: enhancer-like sequences and their role in the regulation of class I gene expression.
Kimura A, Israël A, Le Bail O, Kourilsky P
Cell. 1986
PubMed ID: 3510743
A mutational hot-spot within an intron of the mouse beta 2-microglobulin gene.
Parnes JR, Sizer KC, Seidman JG, Stallings V, Hyman R
EMBO J. 1986
PubMed ID: 3514206
Chromosomal assignment of two endogenous ecotropic murine leukemia virus proviruses of the AKR/J mouse strain.
Taylor BA, Rowe L, Jenkins NA, Copeland NG
J Virol. 1985
PubMed ID: 2993648
CTL and serologically defined antigens of B2m,H-3 region.
Kurtz ME, Graff RJ, Adelman A, Martin-Morgan D, Click RE
J Immunol. 1985
PubMed ID: 2411816
In vitro formation of amyloid fibrils from intact beta 2-microglobulin.
Connors LH, Shirahama T, Skinner M, Fenves A, Cohen AS
Biochem Biophys Res Commun. 1985
PubMed ID: 2413854
The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.
Roehm NW, Carbone A, Kushnir E, Taylor BA, Riblet RJ, Marrack P, Kappler JW
J Immunol. 1985
PubMed ID: 2410514
Gm-3.2, a new granulocyte/macrophage alloantigen.
Hibbs ML, Hogarth PM, Harris RA, McKenzie IF
Immunogenetics. 1985
PubMed ID: 3967899
A new beta-2 microglobulin allele in mice defined by DNA sequencing.
Gasser DL, Klein KA, Choi E, Seidman JG
Immunogenetics. 1985
PubMed ID: 3902633
Histidine decarboxylase phenotypes of inbred mouse strains: a regulatory locus (Hdc) determines kidney enzyme concentration.
Martin SA, Taylor BA, Watanabe T, Bulfield G
Biochem Genet. 1984
PubMed ID: 6732748
Beta-2 microglobulin types in mice of wild origin.
Robinson PJ, Steinmetz M, Moriwaki K, Lindahl KF
Immunogenetics. 1984
PubMed ID: 6096267
A lymphocyte antigen encoded by a locus closely linked to H-3 on the second chromosome of the mouse.
Gasser DL, Ziebur J, Matsumoto K
Proc Natl Acad Sci U S A. 1983
PubMed ID: 6356130
Linkage of beta 2-microglobulin and ly-m11 by molecular cloning and DNA-mediated gene transfer.
Margulies DH, Parnes JR, Johnson NA, Seidman JG
Proc Natl Acad Sci U S A. 1983
PubMed ID: 6188162
Structure and expression of the mouse beta 2-microglobulin gene isolated from somatic and non-expressing teratocarcinoma cells.
Daniel F, Morello D, Le Bail O, Chambon P, Cayre Y, Kourilsky P
EMBO J. 1983
PubMed ID: 6354707
Genetics of beta-2 microglobulin in the mouse.
Michaelson J
Immunogenetics. 1983
PubMed ID: 6187676
The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon.
Rosa F, Berissi H, Weissenbach J, Maroteaux L, Fellous M, Revel M
EMBO J. 1983
PubMed ID: 11894933
Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2.
Meruelo D, Offer M, Rossomando A
Proc Natl Acad Sci U S A. 1982
PubMed ID: 6961423
Structure of wild-type and mutant mouse beta 2-microglobulin genes.
Parnes JR, Seidman JG
Cell. 1982
PubMed ID: 6180834
Absence of significant H-2 and beta 2-microglobulin mRNA expression by mouse embryonal carcinoma cells.
Morello D, Daniel F, Baldacci P, Cayre Y, Gachelin G, Kourilsky P
Nature. 1982
PubMed ID: 6174872
Genetic characterization of a polymorphic murine cell-surface glycoprotein.
Lesley J, Trowbridge IS
Immunogenetics. 1982
PubMed ID: 7068175
Gene for a major cell surface glycoprotein of mouse macrophages and other phagocytic cells is on chromosome 2.
Colombatti A, Hughes EN, Taylor BA, August JT
Proc Natl Acad Sci U S A. 1982
PubMed ID: 6952244
Assignment of the gene for beta 2-microglobulin (B2m) to mouse chromosome 2.
Cox DR, Sawicki JA, Yee D, Appella E, Epstein CJ
Proc Natl Acad Sci U S A. 1982
PubMed ID: 6177004
Monoclonal antibody to an alloantigenic determinant on beta2-microglobulin (beta 2M) of the mouse.
Chorney M, Shen FW, Michaelson J, Boyse EA
Immunogenetics. 1982
PubMed ID: 6180984
Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin.
Suggs SV, Wallace RB, Hirose T, Kawashima EH, Itakura K
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6171820
Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.
Parnes JR, Velan B, Felsenfeld A, Ramanathan L, Ferrini U, Appella E, Seidman JG
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6166005
Evidence for linkage of murine beta 2-microglobulin to H-3 and Ly-4.
Goding JW
J Immunol. 1981
PubMed ID: 6162896
Murine lymphocyte alloantigens: the Ly-4 locus.
Potter TA, McKenzie IF, Cherry MC
J Immunogenet. 1981
PubMed ID: 6972979
Two allelic forms of mouse beta 2-microglobulin.
Robinson PJ, Graf L, Sege K
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6165007
Location of the mouse beta 2-microglobulin gene B2m determined by linkage analysis.
Robinson PJ, Lundin L, Sege K, Graf L, Wigzell H, Peterson PA
Immunogenetics. 1981
PubMed ID: 6174441
The presence of Ly-m11 alloantigen in mouse body fluids.
Kimura S, Tada N, Liu Y, Hämmerling U
Immunogenetics. 1981
PubMed ID: 6174440
Complete amino acid sequence of murine beta 2-microglobulin: structural evidence for strain-related polymorphism.
Gates FT, Coligan JE, Kindt TJ
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6165997
Genetic polymorphism of beta 2-microglobulin (B2m) maps to the H-3 region of chromosome 2.
Michaelson J
Immunogenetics. 1981
PubMed ID: 6164636
Genetic polymorphism of murine beta 2-microglobulin detected biochemically.
Michaelson J, Rothenberg E, Boyse EA
Immunogenetics. 1980
PubMed ID: 6160099
Ly-m11: the H-3 region of mouse chromosome 2 controls a new surface alloantigen.
Tada N, Kimura S, Hatzfeld A, Hämmerling U
Immunogenetics. 1980
PubMed ID: 6242882
Assembly and maturation of HLA-A and HLA-B antigens in vivo.
Krangel MS, Orr HT, Strominger JL
Cell. 1979
PubMed ID: 93026
Partial amino acid sequence of mouse beta2-microglobulin.
Appella E, Tanigaki N, Natori T, Pressman D
Biochem Biophys Res Commun. 1976
PubMed ID: 59595
The complete amino acid sequence of beta 2-microglobulin.
Cunningham BA, Wang JL, Berggård I, Peterson PA
Biochemistry. 1973
PubMed ID: 4586824

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	567	12010	24223
EnsEMBL Gene(s)	ENSG00000166710	ENSMUSG00000060802	ENSRNOG00000017123
Unigene	Hs.534255	Mm.163	Rn.1868
Homologene	B2M	B2m	B2m
OMIM	109700	N/A	N/A
GeneCards	B2M	N/A	N/A
Beta Cell Genomics	DT.100060562 DT.100061071 DT.100689059 DT.100744805 DT.100744815 DT.100744823 DT.100744850 DT.100744876 DT.101986470 DT.91677800 DT.91687294 DT.91784683 DT.91784806 DT.91869130 DT.91945313	DT.101310646 DT.102553038 DT.525199 DT.537741 DT.97351078	N/A
Reactome	P61769	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	567	12010	24223

External resources from NIDDK Consortium Interconnectivity Network Top Help

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View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
B2M	LILRB1	HPRD	empirical	12897781
B2M	PRSS23	HPRD, MINT, IntAct, BioGRID	empirical	16169070
B2M	LIN54	IntAct	empirical	17531812
B2M	A2M	HPRD, BioGRID	empirical	10731476
B2M	FCGRT	HPRD, MINT, IntAct	empirical	12006623 10933786 11336709
B2M	GRB2	IntAct, BioGRID	empirical	18624398
B2M	PDIA3	Reactome	predicted	10064069 2450918 14681859
B2M	HFE	HPRD, IntAct	empirical	10791995 10638746
B2M	HLA-A	HPRD, MINT, Reactome	empirical	93026 11502003 1448153
B2M	HLA-B	HPRD, MINT, Reactome	empirical	11738047 2450918 10975842 8624812 8624811 12244049
B2M	HLA-C	HPRD, MINT, Reactome	empirical	2450918 10429675
B2M	HLA-E	HPRD, BioGRID, Reactome	empirical	9605335 10064069
B2M	HLA-F	HPRD, Reactome	empirical	11169396
B2M	HLA-G	HPRD, Reactome	empirical	9228302
B2M	LIN37	IntAct	empirical	17531812
B2M	B2M	HPRD	empirical	12023961
B2M	TAP1	IntAct, BioGRID	empirical	17055437 19366690
B2M	TFRC	IntAct	empirical	10638746
B2M	UBC	BioGRID	empirical	18781797 21139048
B2M	BAG6	HPRD, MINT, IntAct, BioGRID	empirical	16169070
B2M	CALR	HPRD	empirical	8769474
B2M	CD1A	HPRD, IntAct	empirical	12833155 15723809
B2M	CD1B	HPRD, MINT, IntAct	empirical	12118248 14764708
B2M	CD1D	HPRD, IntAct	empirical	11257307 10221650 9219685
B2M	CD1E	HPRD	empirical	10948205
B2M	CD8A	HPRD	empirical	11914379
B2M	KIAA0101	BioGRID	empirical	21628590