RNLS

  Summary from T1DBase   Top   Help
Gene Description:   renalase, FAD-dependent amine oxidase
Synonyms:   AI452315, Rnls, FLJ11218, RNLS, AW060440, RGD1309804, 6530404N21Rik, C10orf59, RENALASE
Orthologs:   Human RNLS (protein-coding), Mouse Rnls (protein-coding), Rat Rnls (protein-coding)
 
expander Sources
  Regions of Interest Overlapping this feature from T1DBase   Top   Help
Regions Overlapping this Feature:  Human: 1 Mouse: 1 Rat: 1
expander Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Region Species Chromosomal Location Mb Number of genes Marker
10q23.31 Human chr10:90008047..90278380 0.27 6 rs10509540
expander Other Regions: Available
  Gene Overview from T1DBase   Top   Help
expander (Human) GRCh37 - chr10:90033621..90344287 (310.67 kb)  View in Genome Browser
expander (Mouse) NCBIM37 - chr19:33212234..33466785 (254.55 kb)  View in Genome Browser
expander (Rat) RGSC3.4 - chr1:237364578..237639800 (275.22 kb)  View in Genome Browser
  Beta Cell Gene Atlas from T1DBase   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
Human Mouse Rat
ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas
 
 
 
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expander Expression Legend
  Tissue Expression   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
/expression/atlas-PB_CD14+_Monocytes.png /expression/atlas-PB_CD56+_NK_Cells.png /expression/atlas-PB_CD19-_B_Cells.png /expression/atlas-PB_CD4+_T_Cells.png /expression/atlas-PB_CD8+_T_Cells.png /expression/atlas-PB_BDCA4+_Dendritic_Cells.png /expression/atlas-721_B_Lymphoblasts.png /expression/atlas-Lymph_Node.png /expression/atlas-Thymus.png /expression/atlas-Salivary_Gland.png /expression/atlas-Bone_Marrow.png /expression/atlas-BM_CD34+.png /expression/atlas-Heart.png /expression/atlas-Skeletal_Muscle.png /expression/atlas-Kidney.png /expression/atlas-Liver.png /expression/atlas-Lung.png /expression/atlas-Pancreas.png /expression/atlas-Pancreatic_Islets.png /expression/atlas-Trachea.png /expression/atlas-Pituitary.png /expression/atlas-Thyroid.png /expression/atlas-Amygdala.png /expression/atlas-Caudate_Nucleus.png /expression/atlas-Cerebellum.png /expression/atlas-Hypothalamus.png /expression/atlas-Spinal_cord.png /expression/atlas-Thalamus.png /expression/atlas-Skin.png /expression/atlas-Ovary.png /expression/atlas-Placenta.png /expression/atlas-Prostate.png /expression/atlas-Testis.png /expression/atlas-Uterus.png
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  HaemAtlas Expression   Top   Help
Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.
CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56
Expression Pattern High High Not Detected High Moderate Moderate Moderate Moderate HaemAtlasProfile
expander Expression Legend
  Interactions from T1DBase   Top   Help
expander Interactions Table for RNLS:
  Cross-Reference to Pathways and GO Terms   Top   Help
expander View all
KEGG Network: None available
Biocarta: None available
Reactome: None available
NCI-Nature Pathway Interaction Database: None available
expander Gene Ontology: 2
  Publications   Top   Help
expander Type 1 Diabetes Publications: 1
expander Publications: 30
  Model Organism Phenotype Links   Top   Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
Organism Phenotype Resources
Mouse MGI:1915045 IKMC
  External Links   Top   Help
  Human Mouse Rat
Entrez Gene 55328 67795 361751
EnsEMBL Gene(s) ENSG00000184719 ENSMUSG00000071573 ENSRNOG00000020705
Unigene Hs.149849 Mm.204591 Rn.15885
Homologene RNLS Rnls Rnls
OMIM 609360 N/A N/A
GeneCards RNLS N/A N/A
Beta Cell Genomics DT.101208 DT.101955364 DT.91759114 DT.50316099 N/A
Reactome N/A N/A N/A
Plasma Peptide Atlas N/A N/A N/A
MGI N/A MGI:1915045 N/A
WikiGenes 55328 67795 361751
  External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network   Top   Help
dkCOIN_click Relevant resources:
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