PPP2R2B

Summary Top Help

Gene Description:

protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform; protein phosphatase 2, regulatory subunit B, beta

Synonyms:

PR52B, B55BETA, PR55BETA, PR2AB55BETA, Ppp2r2b, PPP2R2B, PR2APR55BETA, 6330404L05Rik, PP2APR55B, Pppr2b2, E130009M08Rik, PP2AB55BETA, PR2ABBETA, PR55-BETA, PP2A-PR55B, SCA12, PP2APR55BETA, 2900026H06Rik, PP2ABBETA

Orthologs:

Human PPP2R2B (protein-coding), Mouse Ppp2r2b (protein-coding), Rat Ppp2r2b (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Rat: 1

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm35	Rat	chr18:4320091..76880933	72.56	466

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr5:145967936..146461054 (493.12 kb) View in Genome Browser

(Mouse) NCBIM37 - chr18:42797086..43219125 (4224 kb) View in Genome Browser

(Rat) RGSC3.4 - chr18:35865837..36318308 (452.47 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for PPP2R2B:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for PPP2R2B:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 4

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: 2

Gene Ontology: 11

Publications from PubMed Top Help

Publications: 96

Spinocerebellar ataxia type 12.
O'Hearn E, Holmes SE, Margolis RL
Handb Clin Neurol. 2012
PubMed ID: 21827912
Induction of PP2A Bβ, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus.
Crispín JC, Apostolidis SA, Finnell MI, Tsokos GC
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21746932
Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12).
Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, Su MT
J Biol Chem. 2011
PubMed ID: 21471219
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.
Tan J, Lee PL, Li Z, Jiang X, Lim YC, Hooi SC, Yu Q
Cancer Cell. 2010
PubMed ID: 21075311
Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population.
Kimura R, Morihara T, Kudo T, Kamino K, Takeda M
Neurosci Lett. 2010
PubMed ID: 21029765
Mapping of autosomal dominant cerebellar ataxia without the pathogenic PPP2R2B mutation to the locus for spinocerebellar ataxia 12.
Sato K, Yabe I, Fukuda Y, Soma H, Nakahara Y, Tsuji S, Sasaki H
Arch Neurol. 2010
PubMed ID: 20937954
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
The CAG repeat in SCA12 functions as a cis element to up-regulate PPP2R2B expression.
Lin CH, Chen CM, Hou YT, Wu YR, Hsieh-Li HM, Su MT, Lee-Chen GJ
Hum Genet. 2010
PubMed ID: 20533062
A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence.
Vazquez A, Kulkarni D, Grochola LF, Bond GL, Barnard N, Toppmeyer D, Levine AJ, Hirshfield KM
Int J Cancer. 2010
PubMed ID: 20669227
Spinocerebellar ataxia type 12 identified in two Italian families may mimic sporadic ataxia.
Brussino A, Graziano C, Giobbe D, Ferrone M, Dragone E, Arduino C, Lodi R, Tonon C, Gabellini A, Rinaldi R, Miccoli S, Grosso E, Bellati MC, Orsi L, Migone N, Brusco A
Mov Disord. 2010
PubMed ID: 20629122
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes Immun. 2010
PubMed ID: 20237496
DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response.
Dejeux E, Rønneberg JA, Solvang H, Bukholm I, Geisler S, Aas T, Gut IG, Børresen-Dale AL, Lønning PE, Kristensen VN, Tost J
Mol Cancer. 2010
PubMed ID: 20338046
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer.
Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J
Breast Cancer Res. 2010
PubMed ID: 20056007
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.
O'Shaughnessy RF, Welti JC, Sully K, Byrne C
Development. 2009
PubMed ID: 19762425
Genome-wide association study of alcohol dependence.
Treutlein J, Cichon S, Ridinger M, Wodarz N, Soyka M, Zill P, Maier W, Moessner R, Gaebel W, Dahmen N, Fehr C, Scherbaum N, Steffens M, Ludwig KU, Frank J, Wichmann HE, Schreiber S, Dragano N, Sommer WH, Leonardi-Essmann F, Lourdusamy A, Gebicke-Haerter P, Wienker TF, Sullivan PF, Nöthen MM, Kiefer F, Spanagel R, Mann K, Rietschel M
Arch Gen Psychiatry. 2009
PubMed ID: 19581569
The genetic aetiology of late-onset chronic progressive cerebellar ataxia. A population-based study.
Wardle M, Majounie E, Muzaimi MB, Williams NM, Morris HR, Robertson NP
J Neurol. 2009
PubMed ID: 19259763
The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation.
Van Kanegan MJ, Strack S
Mol Cell Biol. 2009
PubMed ID: 19029245
Oxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bbeta2).
Cheng WT, Guo ZX, Lin CA, Lin MY, Tung LC, Fang K
BMC Cell Biol. 2009
PubMed ID: 20017961
An integrated workflow for charting the human interaction proteome: insights into the PP2A system.
Glatter T, Wepf A, Aebersold R, Gstaiger M
Mol Syst Biol. 2009
PubMed ID: 19156129
The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission.
Dagda RK, Merrill RA, Cribbs JT, Chen Y, Hell JW, Usachev YM, Strack S
J Biol Chem. 2008
PubMed ID: 18940801
Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia.
Rajkiewicz M, Sułek-Piatkowska A, Krysa W, Zdzienicka E, Szirkowiec W, Zaremba J
Neurol Neurochir Pol. 2008
PubMed ID: 19235102
Adenovirus E4orf4 protein downregulates MYC expression through interaction with the PP2A-B55 subunit.
Ben-Israel H, Sharf R, Rechavi G, Kleinberger T
J Virol. 2008
PubMed ID: 18653458
Spinocerebellar ataxia type 12 was not found in Korean Parkinsonian patients.
Cho JW, Kim SY, Park SS, Jeon BS
Can J Neurol Sci. 2008
PubMed ID: 18973067
Molecular genetics of successful smoking cessation: convergent genome-wide association study results.
Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R, Lerman C
Arch Gen Psychiatry. 2008
PubMed ID: 18519826
PPP2R2B CAG repeat length in the Han Chinese in Taiwan: Association analyses in neurological and psychiatric disorders and potential functional implications.
Chen CM, Hou YT, Liu JY, Wu YR, Lin CH, Fung HC, Hsu WC, Hsu Y, Lee SH, Hsieh-Li HM, Su MT, Chen ST, Lane HY, Lee-Chen GJ
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 18484086
Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.
Liu WB, Li Y, Zhang L, Chen HG, Sun S, Liu JP, Liu Y, Li DW
Mol Vis. 2008
PubMed ID: 18432318
Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.
Chen Y, Xu Y, Bao Q, Xing Y, Li Z, Lin Z, Stock JB, Jeffrey PD, Shi Y
Nat Struct Mol Biol. 2007
PubMed ID: 17529992
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.
Cannavo E, Gerrits B, Marra G, Schlapbach R, Jiricny J
J Biol Chem. 2007
PubMed ID: 17148452
A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55.
Li HH, Cai X, Shouse GP, Piluso LG, Liu X
EMBO J. 2007
PubMed ID: 17245430
Rac1-induced cell migration requires membrane recruitment of the nuclear oncogene SET.
ten Klooster JP, Leeuwen I, Scheres N, Anthony EC, Hordijk PL
EMBO J. 2007
PubMed ID: 17245428
Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.
Seshadri S, DeStefano AL, Au R, Massaro JM, Beiser AS, Kelly-Hayes M, Kase CS, D'Agostino RB, Decarli C, Atwood LD, Wolf PA
BMC Med Genet. 2007
PubMed ID: 17903297
Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest.
Arachchige Don AS, Dallapiazza RF, Bennin DA, Brake T, Cowan CE, Horne MC
Exp Cell Res. 2006
PubMed ID: 17123511
Role of protein phosphatase 2A in the regulation of endothelial cell cytoskeleton structure.
Tar K, Csortos C, Czikora I, Olah G, Ma SF, Wadgaonkar R, Gergely P, Garcia JG, Verin AD
J Cell Biochem. 2006
PubMed ID: 16475161
Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells.
Liang X, Reed E, Yu JJ
Int J Mol Med. 2006
PubMed ID: 16596250
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Involvement of protein phosphatase 2A in the maintenance of E-cadherin-mediated cell-cell adhesion through recruitment of IQGAP1.
Takahashi K, Nakajima E, Suzuki K
J Cell Physiol. 2006
PubMed ID: 16245300
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein.
Neviani P, Santhanam R, Trotta R, Notari M, Blaser BW, Liu S, Mao H, Chang JS, Galietta A, Uttam A, Roy DC, Valtieri M, Bruner-Klisovic R, Caligiuri MA, Bloomfield CD, Marcucci G, Perrotti D
Cancer Cell. 2005
PubMed ID: 16286244
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
Kray AE, Carter RS, Pennington KN, Gomez RJ, Sanders LE, Llanes JM, Khan WN, Ballard DW, Wadzinski BE
J Biol Chem. 2005
PubMed ID: 16126728
mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.
Hui L, Rodrik V, Pielak RM, Knirr S, Zheng Y, Foster DA
J Biol Chem. 2005
PubMed ID: 16109716
Expanded trinucleotide repeats in the TBP/SCA17 gene mapped to chromosome 6q27 are associated with schizophrenia.
Chen CM, Lane HY, Wu YR, Ro LS, Chen FL, Hung WL, Hou YT, Lin CY, Huang SY, Chen IC, Soong BW, Li ML, Hsieh-Li HM, Su MT, Lee-Chen GJ
Schizophr Res. 2005
PubMed ID: 16054804
Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP 2 A and PP5 estimated by tail-pinch test in mice.
Maeda T, Hamabe W, Gao Y, Fukazawa Y, Kumamoto K, Ozaki M, Kishioka S
Brain Res. 2005
PubMed ID: 16102737
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Evidence of a common founder for SCA12 in the Indian population.
Bahl S, Virdi K, Mittal U, Sachdeva MP, Kalla AK, Holmes SE, O'Hearn E, Margolis RL, Jain S, Srivastava AK, Mukerji M
Ann Hum Genet. 2005
PubMed ID: 16138911
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.
Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, Rapp UR, Rudel T
Nat Cell Biol. 2005
PubMed ID: 16041367
Unfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2A.
Dagda RK, Barwacz CA, Cribbs JT, Strack S
J Biol Chem. 2005
PubMed ID: 15923182
HIV-1 viral protein R (Vpr) & host cellular responses.
Zhao RY, Bukrinsky M, Elder RT
Indian J Med Res. 2005
PubMed ID: 15817944
High-throughput mapping of a dynamic signaling network in mammalian cells.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL
Science. 2005
PubMed ID: 15761153
Viral infections and cell cycle G2/M regulation.
Zhao RY, Elder RT
Cell Res. 2005
PubMed ID: 15780175
Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.
Janoo A, Morrow PW, Tung HY
J Cell Biochem. 2005
PubMed ID: 15578586
Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.
Ammosova T, Washington K, Debebe Z, Brady J, Nekhai S
Retrovirology. 2005
PubMed ID: 16048649
The Vpr protein from HIV-1: distinct roles along the viral life cycle.
Le Rouzic E, Benichou S
Retrovirology. 2005
PubMed ID: 15725353
The role of Vpr in HIV-1 pathogenesis.
Andersen JL, Planelles V
Curr HIV Res. 2005
PubMed ID: 15638722
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
The DNA sequence and comparative analysis of human chromosome 5.
Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM
Nature. 2004
PubMed ID: 15372022
Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.
Brusco A, Gellera C, Cagnoli C, Saluto A, Castucci A, Michielotto C, Fetoni V, Mariotti C, Migone N, Di Donato S, Taroni F
Arch Neurol. 2004
PubMed ID: 15148151
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Polymorphism of trinucleotide repeats in non-translated regions of SCA8 and SCA12 genes: allele distribution in a Polish control group.
Sułek A, Hoffman-Zacharska D, Bednarska-Makaruk M, Szirkowiec W, Zaremba J
J Appl Genet. 2004
PubMed ID: 14960773
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.
Shern JF, Sharer JD, Pallas DC, Bartolini F, Cowan NJ, Reed MS, Pohl J, Kahn RA
J Biol Chem. 2003
PubMed ID: 12912990
A developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosis.
Dagda RK, Zaucha JA, Wadzinski BE, Strack S
J Biol Chem. 2003
PubMed ID: 12716901
CAG repeat polymorphisms in KCNN3 (HSKCa3) and PPP2R2B show no association or linkage to schizophrenia.
Laurent C, Niehaus D, Bauché S, Levinson DF, Soubigou S, Pimstone S, Hayden M, Mbanga I, Emsley R, Deleuze JF, Mallet J
Am J Med Genet B Neuropsychiatr Genet. 2003
PubMed ID: 12497613
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A.
Schmidt K, Kins S, Schild A, Nitsch RM, Hemmings BA, Götz J
Eur J Neurosci. 2002
PubMed ID: 12473071
Bestrophin interacts physically and functionally with protein phosphatase 2A.
Marmorstein LY, McLaughlin PJ, Stanton JB, Yan L, Crabb JW, Marmorstein AD
J Biol Chem. 2002
PubMed ID: 12058047
Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest.
Bennin DA, Don AS, Brake T, McKenzie JL, Rosenbaum H, Ortiz L, DePaoli-Roach AA, Horne MC
J Biol Chem. 2002
PubMed ID: 11956189
Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A.
Hrimech M, Yao XJ, Branton PE, Cohen EA
EMBO J. 2002
PubMed ID: 12110603
Analysis of SCA8 and SCA12 loci in 134 Italian ataxic patients negative for SCA1-3, 6 and 7 CAG expansions.
Brusco A, Cagnoli C, Franco A, Dragone E, Nardacchione A, Grosso E, Mortara P, Mutani R, Migone N, Orsi L
J Neurol. 2002
PubMed ID: 12140678
Cyclin G recruits PP2A to dephosphorylate Mdm2.
Okamoto K, Li H, Jensen MR, Zhang T, Taya Y, Thorgeirsson SS, Prives C
Mol Cell. 2002
PubMed ID: 11983168
ATM-dependent dissociation of B55 regulatory subunit from nuclear PP2A in response to ionizing radiation.
Guo CY, Brautigan DL, Larner JM
J Biol Chem. 2002
PubMed ID: 11723136
HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.
Elder RT, Yu M, Chen M, Zhu X, Yanagida M, Zhao Y
Virology. 2001
PubMed ID: 11531413
The sequence of the human genome.
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X
Science. 2001
PubMed ID: 11181995
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
SCA12 is a rare locus for autosomal dominant cerebellar ataxia: a study of an Indian family.
Fujigasaki H, Verma IC, Camuzat A, Margolis RL, Zander C, Lebre AS, Jamot L, Saxena R, Anand I, Holmes SE, Ross CA, Dürr A, Brice A
Ann Neurol. 2001
PubMed ID: 11198281
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A.
Hrimech M, Yao XJ, Branton PE, Cohen EA
EMBO J. 2000
PubMed ID: 10921877
Expansion of a novel CAG trinucleotide repeat in the 5' region of PPP2R2B is associated with SCA12.
Holmes SE, O'Hearn EE, McInnis MG, Gorelick-Feldman DA, Kleiderlein JJ, Callahan C, Kwak NG, Ingersoll-Ashworth RG, Sherr M, Sumner AJ, Sharp AH, Ananth U, Seltzer WK, Boss MA, Vieria-Saecker AM, Epplen JT, Riess O, Ross CA, Margolis RL
Nat Genet. 1999
PubMed ID: 10581021
Regulation of protein kinase cascades by protein phosphatase 2A.
Millward TA, Zolnierowicz S, Hemmings BA
Trends Biochem Sci. 1999
PubMed ID: 10322434
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.
Strack S, Zaucha JA, Ebner FF, Colbran RJ, Wadzinski BE
J Comp Neurol. 1998
PubMed ID: 9514514
Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.
Ruediger R, Brewis N, Ohst K, Walter G
Virology. 1997
PubMed ID: 9400615
Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.
Tung HY, De Rocquigny H, Zhao LJ, Cayla X, Roques BP, Ozon R
FEBS Lett. 1997
PubMed ID: 9013886
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
cDNA cloning of BR gamma, a novel brain-specific isoform of the B regulatory subunit of type-2A protein phosphatase.
Akiyama N, Shima H, Hatano Y, Osawa Y, Sugimura T, Nagao M
Eur J Biochem. 1995
PubMed ID: 7607250
Expression of PP2A B regulatory subunit beta isotype in rat testis.
Hatano Y, Shima H, Haneji T, Miura AB, Sugimura T, Nagao M
FEBS Lett. 1993
PubMed ID: 8389301
Direct detection of novel expanded trinucleotide repeats in the human genome.
Schalling M, Hudson TJ, Buetow KH, Housman DE
Nat Genet. 1993
PubMed ID: 8348150
Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform.
Mayer RE, Hendrix P, Cron P, Matthies R, Stone SR, Goris J, Merlevede W, Hofsteenge J, Hemmings BA
Biochemistry. 1991
PubMed ID: 1849734
Federation of American Societies for Experimental Biology. 75th Annual Meeting. Atlanta, Georgia, April 21-25, 1991. Part II. Abstracts.

FASEB J. 1991
PubMed ID: 2001796
The publication is not currently in our database, click on the link below to see it on pubmed.
PubMed ID:

Model Organism Phenotype Links from MGI Top Help

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External Links Top Help

	Human	Mouse	Rat
Entrez Gene	5521	72930	60660
EnsEMBL Gene(s)	ENSG00000156475	ENSMUSG00000024500	ENSRNOG00000018851
Unigene	Hs.655213	Mm.26134	Rn.44437
Homologene	PPP2R2B	Ppp2r2b	Ppp2r2b
OMIM	604325	N/A	N/A
GeneCards	PPP2R2B	N/A	N/A
Beta Cell Genomics	DT.100747942 DT.100777757 DT.120873123 DT.313805 DT.91718449 DT.95102002 DT.95102005	DT.101370879 DT.101370880 DT.50315525 DT.87028032 DT.91401956	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	5521	72930	60660

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Interactor	Interactor	Sources	Classification	Pubmed IDs
PPP2R2B	SMC4	IntAct	empirical	19156129
PPP2R2B	SUGP2	IntAct	empirical	19156129
PPP2R2B	TRIM28	IntAct, BioGRID	empirical	19156129
PPP2R2B	RBM7	IntAct	empirical	19156129
PPP2R2B	TUBA1B	IntAct	empirical	19156129
PPP2R2B	TUBB4B	IntAct	empirical	19156129
PPP2R2B	DDX17	IntAct	empirical	19156129
PPP2R2B	PRDX4	IntAct	empirical	19156129
PPP2R2B	CCT7	IntAct, BioGRID	empirical	19156129
PPP2R2B	CCT4	IntAct, BioGRID	empirical	19156129
PPP2R2B	CCT2	IntAct, BioGRID	empirical	19156129
PPP2R2B	CCT8	IntAct, BioGRID	empirical	19156129
PPP2R2B	PRDX3	IntAct	empirical	19156129
PPP2R2B	CHEK2	HPRD	empirical	16596250
PPP2R2B	ATXN2L	IntAct, BioGRID	empirical	19156129
PPP2R2B	GABARAP	IntAct	empirical	20562859
PPP2R2B	GABARAPL2	IntAct	empirical	17353931
PPP2R2B	FAM122A	BioGRID	empirical	19156129
PPP2R2B	DCD	IntAct	empirical	19156129
PPP2R2B	LSM12	IntAct	empirical	19156129
PPP2R2B	SGOL2	IntAct	empirical	19156129
PPP2R2B	DDX3X	IntAct	empirical	19156129
PPP2R2B	DDX6	IntAct	empirical	19156129
PPP2R2B	DSG1	IntAct	empirical	19156129
PPP2R2B	DSP	IntAct	empirical	19156129
PPP2R2B	ECH1	IntAct	empirical	19156129
PPP2R2B	EEF1A1	IntAct	empirical	19156129
PPP2R2B	EEF1A2	IntAct	empirical	19156129
PPP2R2B	EEF1B2	IntAct	empirical	19156129
PPP2R2B	KRT78	IntAct	empirical	19156129
PPP2R2B	ELAVL1	IntAct	empirical	19156129
PPP2R2B	TUBB	IntAct	empirical	19156129
PPP2R2B	R3HCC1	IntAct	empirical	19156129
PPP2R2B	ALB	IntAct	empirical	19156129
PPP2R2B	PTK2B	IntAct	empirical	19156129
PPP2R2B	SKA1	IntAct, BioGRID	empirical	19156129
PPP2R2B	SKA3	IntAct, BioGRID	empirical	19156129
PPP2R2B	CCT5	IntAct, BioGRID	empirical	19156129
PPP2R2B	MRPS27	IntAct	empirical	19156129
PPP2R2B	SIK2	IntAct	empirical	19156129
PPP2R2B	SOGA2	IntAct	empirical	19156129
PPP2R2B	SKIV2L2	IntAct, BioGRID	empirical	19156129
PPP2R2B	PSD4	IntAct	empirical	19156129
PPP2R2B	GABARAPL1	IntAct	empirical	20562859
PPP2R2B	FTSJ1	IntAct	empirical	17353931
PPP2R2B	SERBP1	IntAct	empirical	19156129
PPP2R2B	DAZAP1	IntAct	empirical	19156129
PPP2R2B	PABPC1	IntAct	empirical	19156129
PPP2R2B	HCFC2	IntAct	empirical	19156129
PPP2R2B	HIST1H1E	IntAct	empirical	19156129
PPP2R2B	ANXA2	IntAct	empirical	19156129
PPP2R2B	HCFC1	IntAct	empirical	19156129
PPP2R2B	ACACA	IntAct	empirical	19156129
PPP2R2B	HNRNPA2B1	IntAct	empirical	19156129
PPP2R2B	HNRNPF	IntAct	empirical	19156129
PPP2R2B	HNRNPH1	IntAct	empirical	19156129
PPP2R2B	HNRNPK	IntAct	empirical	19156129
PPP2R2B	HNRNPL	IntAct	empirical	19156129
PPP2R2B	HNRNPU	IntAct	empirical	19156129
PPP2R2B	ACACB	IntAct	empirical	19156129
PPP2R2B	HSPA5	IntAct	empirical	19156129
PPP2R2B	HSPA8	IntAct	empirical	19156129
PPP2R2B	HSPA9	IntAct	empirical	19156129
PPP2R2B	HSP90AA1	IntAct	empirical	19156129
PPP2R2B	HSPD1	IntAct	empirical	19156129
PPP2R2B	SKA2	IntAct, BioGRID	empirical	19156129
PPP2R2B	JUN	IntAct	empirical	19156129
PPP2R2B	JUP	IntAct	empirical	19156129
PPP2R2B	KPNB1	IntAct	empirical	19156129
PPP2R2B	KRT1	IntAct	empirical	19156129
PPP2R2B	KRT2	IntAct	empirical	19156129
PPP2R2B	KRT5	IntAct	empirical	19156129
PPP2R2B	KRT6A	IntAct	empirical	19156129
PPP2R2B	KRT6B	IntAct	empirical	19156129
PPP2R2B	KRT9	IntAct	empirical	19156129
PPP2R2B	KRT10	IntAct	empirical	19156129
PPP2R2B	KRT14	IntAct	empirical	19156129
PPP2R2B	KRT16	IntAct	empirical	19156129
PPP2R2B	KRT31	IntAct	empirical	19156129
PPP2R2B	KRT32	IntAct	empirical	19156129
PPP2R2B	KRT33B	IntAct	empirical	19156129
PPP2R2B	KRT81	IntAct	empirical	19156129
PPP2R2B	KRT85	IntAct	empirical	19156129
PPP2R2B	ARRB2	IntAct	empirical	16051150
PPP2R2B	MCM5	IntAct	empirical	19156129
PPP2R2B	MKI67	IntAct	empirical	19156129
PPP2R2B	MLH1	BioGRID	empirical	17148452
PPP2R2B	MYL6	IntAct	empirical	19156129
PPP2R2B	MYO9A	IntAct, BioGRID	empirical	19156129
PPP2R2B	NME2	IntAct	empirical	19156129
PPP2R2B	YBX1	IntAct	empirical	19156129
PPP2R2B	RBMXL1	IntAct	empirical	19156129
PPP2R2B	ZNF295	IntAct, BioGRID	empirical	19156129
PPP2R2B	PRDX1	IntAct	empirical	19156129
PPP2R2B	PAK2	IntAct	empirical	17353931
PPP2R2B	PC	IntAct	empirical	19156129
PPP2R2B	PCCA	IntAct	empirical	19156129
PPP2R2B	PCCB	IntAct	empirical	19156129
PPP2R2B	RPS27L	IntAct	empirical	19156129
PPP2R2B	PCMT1	IntAct	empirical	19156129
PPP2R2B	IER5	IntAct, BioGRID	empirical	19156129
PPP2R2B	PDPK1	IntAct	empirical	21075311
PPP2R2B	CDCA4	IntAct, BioGRID	empirical	19156129
PPP2R2B	PPP2CA	IntAct, BioGRID	empirical	19156129
PPP2R2B	PPP2CB	IntAct, BioGRID	empirical	19156129
PPP2R2B	PPP2R1A	IntAct, BioGRID	empirical	19156129 21075311
PPP2R2B	PPP2R1B	IntAct, BioGRID	empirical	19156129
PPP2R2B	PPP2R2C	BioGRID	empirical	19156129
PPP2R2B	PPP4C	IntAct, BioGRID	empirical	19156129
PPP2R2B	ZCCHC8	IntAct, BioGRID	empirical	19156129
PPP2R2B	PRPF40A	IntAct	empirical	19156129
PPP2R2B	SERTAD4	IntAct, BioGRID	empirical	19156129
PPP2R2B	PRPH	BioGRID	empirical	19156129
PPP2R2B	PRSS1	IntAct	empirical	19156129
PPP2R2B	ZC3HAV1	IntAct, BioGRID	empirical	19156129
PPP2R2B	MCCC1	IntAct	empirical	19156129
PPP2R2B	NUFIP2	IntAct	empirical	19156129
PPP2R2B	KIAA1967	IntAct	empirical	19156129
PPP2R2B	RBM25	IntAct	empirical	19156129
PPP2R2B	RAC1	HPRD	empirical	17245428
PPP2R2B	RAN	IntAct	empirical	19156129
PPP2R2B	ACTB	IntAct	empirical	19156129
PPP2R2B	RPL4	IntAct	empirical	19156129
PPP2R2B	RPL6	IntAct	empirical	19156129
PPP2R2B	RPL7A	IntAct	empirical	19156129
PPP2R2B	RPL11	IntAct	empirical	19156129
PPP2R2B	RPL12	IntAct	empirical	19156129
PPP2R2B	RPL17	IntAct	empirical	19156129
PPP2R2B	RPL19	IntAct	empirical	19156129
PPP2R2B	RPL21	IntAct	empirical	19156129
PPP2R2B	RPL24	IntAct	empirical	19156129
PPP2R2B	RPL30	IntAct	empirical	19156129
PPP2R2B	RPLP0	IntAct	empirical	19156129
PPP2R2B	RPLP1	IntAct	empirical	19156129
PPP2R2B	RPLP2	IntAct	empirical	19156129
PPP2R2B	MRPL12	IntAct	empirical	19156129
PPP2R2B	RPS4X	IntAct	empirical	19156129
PPP2R2B	RPS6	IntAct	empirical	19156129
PPP2R2B	RPS6KB1	IntAct	empirical	21075311
PPP2R2B	RPS8	IntAct	empirical	19156129
PPP2R2B	RPS11	IntAct	empirical	19156129
PPP2R2B	RPS14	IntAct	empirical	19156129
PPP2R2B	RPS23	IntAct	empirical	19156129
PPP2R2B	RPS27	IntAct	empirical	19156129
PPP2R2B	RPS27A	IntAct	empirical	19156129
PPP2R2B	S100A7	IntAct	empirical	19156129
PPP2R2B	S100A8	IntAct	empirical	19156129
PPP2R2B	S100A9	IntAct	empirical	19156129
PPP2R2B	MCCC2	IntAct	empirical	19156129
PPP2R2B	TCP1	IntAct, BioGRID	empirical	19156129
PPP2R2B	C1QBP	IntAct	empirical	19156129
PPP2R2B	TMPO	IntAct	empirical	19156129
PPP2R2B	TP53	HPRD	empirical	17245430
PPP2R2B	CCT3	IntAct, BioGRID	empirical	19156129
PPP2R2B	TUFM	IntAct, BioGRID	empirical	19156129
PPP2R2B	UBC	BioGRID	empirical	21906983
PPP2R2B	VHL	IntAct	empirical	17353931
PPP2R2B	VIM	IntAct	empirical	19156129
PPP2R2B	YWHAE	IntAct	empirical	19156129
PPP2R2B	ZNF136	BioGRID	empirical	19156129
PPP2R2B	CAD	IntAct	empirical	19156129
PPP2R2B	GRPEL1	IntAct	empirical	19156129
PPP2R2B	CAPZA1	IntAct	empirical	19156129
PPP2R2B	CAPZB	IntAct, BioGRID	empirical	19156129
PPP2R2B	IRS4	IntAct	empirical	19156129
PPP2R2B	OGT	IntAct	empirical	19156129
PPP2R2B	TUBA1C	IntAct	empirical	19156129
PPP2R2B	DYNLL1	IntAct	empirical	19156129
PPP2R2B	IQGAP1	IntAct	empirical	19156129
PPP2R2B	RPL14	IntAct	empirical	19156129
PPP2R2B	MAP7	IntAct	empirical	19156129
PPP2R2B	CCT6A	IntAct, BioGRID	empirical	19156129
PPP2R2B	DDX21	IntAct	empirical	19156129
PPP2R2B	RPL23	IntAct	empirical	19156129
PPP2R2B	RECQL4	IntAct	empirical	19156129
PPP2R2B	DNAJA1P5	IntAct	empirical	19156129
PPP2R2B	BAG2	IntAct, BioGRID	empirical	19156129
PPP2R2B	IER2	BioGRID	empirical	19156129
PPP2R2B	MATR3	IntAct	empirical	19156129
PPP2R2B	CDC42	IntAct	empirical	19156129