POU2F1

Summary Top Help

Gene Description:

POU domain, class 2, transcription factor 1; POU class 2 homeobox 1

Synonyms:

Oct1, Otf1, 2810482H01Rik, Otf-1, OCT1, OTF1, oct-1B, NF-A1, POU2F1, Pou2f1, Oct-1

Orthologs:

Human POU2F1 (protein-coding), Mouse Pou2f1 (protein-coding), Rat Pou2f1 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr1:167190066..167396582 (206.52 kb) View in Genome Browser

(Mouse) NCBIM37 - chr1:167795285..167932809 (137.52 kb) View in Genome Browser

(Rat) RGSC3.4 - chr13:81607326..81739958 (132.63 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for POU2F1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for POU2F1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: None available

Reactome: 6

NCI-Nature Pathway Interaction Database: 6

Gene Ontology: 13

Publications from PubMed Top Help

Type 1 Diabetes Publications: 3

Publications: 229

Oct1 regulates cell growth of LNCaP cells and is a prognostic factor for prostate cancer.
Obinata D, Takayama K, Urano T, Murata T, Kumagai J, Fujimura T, Ikeda K, Horie-Inoue K, Homma Y, Ouchi Y, Takahashi S, Inoue S
Int J Cancer. 2012
PubMed ID: 21387309
Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter.
Quan X, Lim SO, Jung G
FEBS Lett. 2011
PubMed ID: 21985966
Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency.
Robinson AR, Kwek SS, Hagemeier SR, Wille CK, Kenney SC
J Virol. 2011
PubMed ID: 21697476
Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia.
Maffioli M, Camós M, Gaya A, Hernández-Boluda JC, Alvarez-Larrán A, Domingo A, Granell M, Guillem V, Vallansot R, Costa D, Bellosillo B, Colomer D, Cervantes F
Leuk Res. 2011
PubMed ID: 21185600
Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol.
Tzvetkov MV, Saadatmand AR, Lötsch J, Tegeder I, Stingl JC, Brockmöller J
Clin Pharmacol Ther. 2011
PubMed ID: 21562485
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells.
Goettsch C, Goettsch W, Brux M, Haschke C, Brunssen C, Muller G, Bornstein SR, Duerrschmidt N, Wagner AH, Morawietz H
Basic Res Cardiol. 2011
PubMed ID: 21399967
Intra- and intermolecular translocation of the bi-domain transcription factor Oct1 characterized by liquid crystal and paramagnetic NMR.
Takayama Y, Clore GM
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21555551
Replication stress induces 53BP1-containing OPT domains in G1 cells.
Harrigan JA, Belotserkovskaya R, Coates J, Dimitrova DS, Polo SE, Bradshaw CR, Fraser P, Jackson SP
J Cell Biol. 2011
PubMed ID: 21444690
Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).
Holt RJ, Zhang Y, Binia A, Dixon AL, Vandiedonck C, Cookson WO, Knight JC, Moffatt MF
J Allergy Clin Immunol. 2011
PubMed ID: 21320718
Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice.
Li S, Chen Y, Zhang S, More SS, Huang X, Giacomini KM
Pharm Res. 2011
PubMed ID: 21104302
OCT-1 function varies with cell lineage but is not influenced by BCR-ABL.
Engler JR, Zannettino AC, Bailey CG, Rasko JE, Hughes TP, White DL
Haematologica. 2011
PubMed ID: 20971815
Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.
Shakya A, Kang J, Chumley J, Williams MA, Tantin D
J Biol Chem. 2011
PubMed ID: 21051540
Dynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination.
Kang J, Goodman B, Zheng Y, Tantin D
PLoS One. 2011
PubMed ID: 21897860
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
OCT1 Expression in adipocytes could contribute to increased metformin action in obese subjects.
Moreno-Navarrete JM, Ortega FJ, Rodríguez-Hermosa JI, Sabater M, Pardo G, Ricart W, Fernández-Real JM
Diabetes. 2011
PubMed ID: 20956498
Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL
Gene Expr Patterns. 2011
PubMed ID: 20932939
Association of the POU class 2 homeobox 1 gene (POU2F1) with susceptibility to Type 2 diabetes in Chinese populations.
Ng MC, Lam VK, Tam CH, Chan AW, So WY, Ma RC, Zee BC, Waye MM, Mak WW, Hu C, Wang CR, Tong PC, Jia WP, Chan JC, International Type 2 Diabetes 1q Consortium
Diabet Med. 2010
PubMed ID: 21059098
Oct1 regulates trophoblast development during early mouse embryogenesis.
Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, Tapia N, Esch D, Ju JY, Hübner K, Bravo MJ, Schöler HR, Cavaleri F, Matthias P
Development. 2010
PubMed ID: 20876643
Oct1 is required for mTOR-induced G1 cell cycle arrest via the control of p27(Kip1) expression.
Dalvai M, Schubart K, Besson A, Matthias P
Cell Cycle. 2010
PubMed ID: 20935455
Facilitated DNA search by multidomain transcription factors: cross talk via a flexible linker.
Vuzman D, Polonsky M, Levy Y
Biophys J. 2010
PubMed ID: 20713004
Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodents.
Lin CJ, Tai Y, Huang MT, Tsai YF, Hsu HJ, Tzen KY, Liou HH
J Neurochem. 2010
PubMed ID: 20477935
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Dev Cell. 2010
PubMed ID: 20412781
Tethered-hopping model for protein-DNA binding and unbinding based on Sox2-Oct1-Hoxb1 ternary complex simulations.
Lian P, Liu LA, Shi Y, Bu Y, Wei D
Biophys J. 2010
PubMed ID: 20371328
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes Immun. 2010
PubMed ID: 20237496
BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.
Harte MT, O'Brien GJ, Ryan NM, Gorski JJ, Savage KI, Crawford NT, Mullan PB, Harkin DP
Cancer Res. 2010
PubMed ID: 20215511
An atlas of combinatorial transcriptional regulation in mouse and man.
Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
Cell. 2010
PubMed ID: 20211142
Oct-1 is responsible for the C-33T polymorphism effect in the IL-4 promoter.
Gervaziev YV, Olenina LV, Krasotkina JV, Lupatov AY, Mazurina SA, Gervazieva VB
Int J Immunogenet. 2010
PubMed ID: 19804407
High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription.
Laurent B, Randrianarison-Huetz V, Marchal V, Mayeux P, Dusanter-Fourt I, Duménil D
Blood. 2010
PubMed ID: 19965638
Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.
Cleynen I, Mahachie John JM, Henckaerts L, Van Moerkercke W, Rutgeerts P, Van Steen K, Vermeire S
PLoS One. 2010
PubMed ID: 20886065
Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response.
Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH
Pharmacogenet Genomics. 2010
PubMed ID: 19898263
Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter.
Kaku H, Rothstein TL
Genes Immun. 2010
PubMed ID: 19710692
Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter.
Astrand C, Belikov S, Wrange O
Exp Cell Res. 2009
PubMed ID: 19463811
Insulin stimulates the expression of carbohydrate response element binding protein (ChREBP) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1.
Sirek AS, Liu L, Naples M, Adeli K, Ng DS, Jin T
Endocrinology. 2009
PubMed ID: 19359385
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C
Gut. 2009
PubMed ID: 19240061
A far-upstream Oct-1 motif regulates cytokine-induced transcription of the human inducible nitric oxide synthase gene.
Park KS, Guo Z, Shao L, Du Q, Geller DA
J Mol Biol. 2009
PubMed ID: 19467240
Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A
Eur J Hum Genet. 2009
PubMed ID: 19536175
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
Multiple core homeodomain binding motifs differentially contribute to transcriptional activity of the murine gonadotropin-releasing hormone receptor gene promoter.
Lents CA, Farmerie TA, Cherrington BD, Clay CM
Endocrine. 2009
PubMed ID: 19333792
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Genetic Risk Profiling and Prediction of Disease Course in Crohn's Disease Patients.
Henckaerts L, Van Steen K, Verstreken I, Cleynen I, Franke A, Schreiber S, Rutgeerts P, Vermeire S
Clin Gastroenterol Hepatol. 2009
PubMed ID: 19422935
Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development.
Jin Z, Liu L, Bian W, Chen Y, Xu G, Cheng L, Jing N
J Biol Chem. 2009
PubMed ID: 19147497
Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.
Shakya A, Cooksey R, Cox JE, Wang V, McClain DA, Tantin D
Nat Cell Biol. 2009
PubMed ID: 19219035
Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.
Weersma RK, Stokkers PC, Cleynen I, Wolfkamp SC, Henckaerts L, Schreiber S, Dijkstra G, Franke A, Nolte IM, Rutgeerts P, Wijmenga C, Vermeire S
Am J Gastroenterol. 2009
PubMed ID: 19174780
Involvement of Oct-1 in the regulation of CDKN1A in response to clinically relevant doses of ionizing radiation.
Nenoi M, Daino K, Nakajima T, Wang B, Taki K, Kakimoto A
Biochim Biophys Acta. 2009
PubMed ID: 19118657
Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions.
Jariwala U, Cogan JP, Jia L, Frenkel B, Coetzee GA
Prostate. 2009
PubMed ID: 19058140
Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.
Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW
Hum Mol Genet. 2009
PubMed ID: 19064610
O-GlcNAc modification of Sp1 inhibits the functional interaction between Sp1 and Oct1.
Lim K, Chang HI
FEBS Lett. 2009
PubMed ID: 19070619
A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress.
Kang J, Gemberling M, Nakamura M, Whitby FG, Handa H, Fairbrother WG, Tantin D
Genes Dev. 2009
PubMed ID: 19171782
Induction of endogenous gamma-globin gene expression with decoy oligonucleotide targeting Oct-1 transcription factor consensus sequence.
Xu XS, Hong X, Wang G
J Hematol Oncol. 2009
PubMed ID: 19327156
Expression of the muscle atrophy factor muscle atrophy F-box is suppressed by testosterone.
Zhao W, Pan J, Wang X, Wu Y, Bauman WA, Cardozo CP
Endocrinology. 2008
PubMed ID: 18599544
Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status.
Dai RP, Yu FX, Goh SR, Chng HW, Tan YL, Fu JL, Zheng L, Luo Y
J Biol Chem. 2008
PubMed ID: 18682386
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.
Yuan X, Waterworth D, Perry JR, Lim N, Song K, Chambers JC, Zhang W, Vollenweider P, Stirnadel H, Johnson T, Bergmann S, Beckmann ND, Li Y, Ferrucci L, Melzer D, Hernandez D, Singleton A, Scott J, Elliott P, Waeber G, Cardon L, Frayling TM, Kooner JS, Mooser V
Am J Hum Genet. 2008
PubMed ID: 18940312
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Analysis of the transcriptional regulation of the FABP2 promoter haplotypes by PPARgamma/RXRalpha and Oct-1.
Böhme M, Nitz I, Döring F, Klapper M
Biochim Biophys Acta. 2008
PubMed ID: 18634911
Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1.
Doucleff M, Clore GM
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18772384
Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors.
Zhou C, Tong Y, Wawrowsky K, Bannykh S, Donangelo I, Melmed S
Endocr Relat Cancer. 2008
PubMed ID: 18550719
Factors affecting sensitivity to antitumor platinum derivatives of human colorectal tumor cell lines.
Kitada N, Takara K, Minegaki T, Itoh C, Tsujimoto M, Sakaeda T, Yokoyama T
Cancer Chemother Pharmacol. 2008
PubMed ID: 18030470
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
Mol Cell. 2008
PubMed ID: 18691976
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium.
Thum T, Borlak J
J Biol Chem. 2008
PubMed ID: 18390905
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.
Ha HY, Kim JB, Cho IH, Joo HJ, Kim KS, Lee KW, Sunwoo H, Im JY, Lee JK, Hong JH, Han PL
Proteomics. 2008
PubMed ID: 18324732
Octamer-binding transcription factor-1 gene is upregulated in primary varicose veins.
Jeong GA, Choi ET, Chang JH
Ann Vasc Surg. 2008
PubMed ID: 18083338
Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.
Hosey AM, Gorski JJ, Murray MM, Quinn JE, Chung WY, Stewart GE, James CR, Farragher SM, Mulligan JM, Scott AN, Dervan PA, Johnston PG, Couch FJ, Daly PA, Kay E, McCann A, Mullan PB, Harkin DP
J Natl Cancer Inst. 2007
PubMed ID: 18000219
Gonadotropin-releasing hormone-1 (GnRH-1) is involved in tooth maturation and biomineralization.
Tiong J, Locastro T, Wray S
Dev Dyn. 2007
PubMed ID: 17948256
EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W
Brief Funct Genomic Proteomic. 2007
PubMed ID: 17967808
DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage.
Schild-Poulter C, Shih A, Tantin D, Yarymowich NC, Soubeyrand S, Sharp PA, Haché RJ
Oncogene. 2007
PubMed ID: 17213819
Defining in vivo transcription factor complexes of the murine CD21 and CD23 genes.
Debnath I, Roundy KM, Weis JJ, Weis JH
J Immunol. 2007
PubMed ID: 17513763
Production of specific mRNA transcripts, usage of an alternate promoter, and octamer-binding transcription factors influence the surface expression levels of the HIV coreceptor CCR5 on primary T cells.
Mummidi S, Adams LM, VanCompernolle SE, Kalkonde M, Camargo JF, Kulkarni H, Bellinger AS, Bonello G, Tagoh H, Ahuja SS, Unutmaz D, Ahuja SK
J Immunol. 2007
PubMed ID: 17442950
Oct-1 is involved in the transcriptional repression of the p15(INK4b) gene.
Hitomi T, Matsuzaki Y, Yasuda S, Kawanaka M, Yogosawa S, Koyama M, Tantin D, Sakai T
FEBS Lett. 2007
PubMed ID: 17316622
Regulation of NF-kappaB-dependent gene expression by the POU domain transcription factor Oct-1.
dela Paz NG, Simeonidis S, Leo C, Rose DW, Collins T
J Biol Chem. 2007
PubMed ID: 17192276
Sox2 and Pou2f1 interact to control lens and olfactory placode development.
Donner AL, Episkopou V, Maas RL
Dev Biol. 2007
PubMed ID: 17140559
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.
Molina H, Horn DM, Tang N, Mathivanan S, Pandey A
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17287340
Involvement of the ubiquitous Oct-1 transcription factor in hormonal induction of beta-casein gene expression.
Dong B, Zhao FQ
Biochem J. 2007
PubMed ID: 16965262
The consensus coding sequences of human breast and colorectal cancers.
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE
Science. 2006
PubMed ID: 16959974
Differential lineage-specific regulation of murine CD45 transcription by Oct-1 and PU.1.
Kwon UK, Yen PH, Collins T, Wells RA
Biochem Biophys Res Commun. 2006
PubMed ID: 16616894
The DNA sequence and biological annotation of human chromosome 1.
Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E
Nature. 2006
PubMed ID: 16710414
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Oct-1 DNA binding activity unresponsive to retinoblastoma protein expression prevents MHC class II induction in a non-small cell lung carcinoma cell line.
Osborne AR, Zhang H, Blanck G
Mol Immunol. 2006
PubMed ID: 16360016
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro.
Lewinsky RH, Jensen TG, Møller J, Stensballe A, Olsen J, Troelsen JT
Hum Mol Genet. 2005
PubMed ID: 16301215
The octamer binding transcription factor Oct-1 is a stress sensor.
Tantin D, Schild-Poulter C, Wang V, Haché RJ, Sharp PA
Cancer Res. 2005
PubMed ID: 16322220
GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene.
Gallagher PG, Liem RI, Wong E, Weiss MJ, Bodine DM
J Biol Chem. 2005
PubMed ID: 16186125
The POU transcription factor Oct-1 represses virus-induced interferon A gene expression.
Mesplède T, Island ML, Christeff N, Petek F, Doly J, Navarro S
Mol Cell Biol. 2005
PubMed ID: 16166650
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.
Rave-Harel N, Miller NL, Givens ML, Mellon PL
J Biol Chem. 2005
PubMed ID: 16002402
Regulation of basal and induced expression of C-reactive protein through an overlapping element for OCT-1 and NF-kappaB on the proximal promoter.
Voleti B, Agrawal A
J Immunol. 2005
PubMed ID: 16116232
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.
Bertolino E, Reddy K, Medina KL, Parganas E, Ihle J, Singh H
Nat Immunol. 2005
PubMed ID: 16025120
Silencing of Fshr occurs through a conserved, hypersensitive site in the first intron.
Hermann BP, Heckert LL
Mol Endocrinol. 2005
PubMed ID: 15817654
Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus.
Shakib K, Norman JT, Fine LG, Brown LR, Godovac-Zimmermann J
Proteomics. 2005
PubMed ID: 15942958
Functional interaction of Oct transcription factors with the family of repeats in Epstein-Barr virus oriP.
Almqvist J, Zou J, Linderson Y, Borestrom C, Altiok E, Zetterberg H, Rymo L, Pettersson S, Ernberg I
J Gen Virol. 2005
PubMed ID: 15831936
Oct-1 counteracts autoinhibition of Runx2 DNA binding to form a novel Runx2/Oct-1 complex on the promoter of the mammary gland-specific gene beta-casein.
Inman CK, Li N, Shore P
Mol Cell Biol. 2005
PubMed ID: 15798204
Identification of hippocampus-related candidate genes for Alzheimer's disease.
Taguchi K, Yamagata HD, Zhong W, Kamino K, Akatsu H, Hata R, Yamamoto T, Kosaka K, Takeda M, Kondo I, Miki T
Ann Neurol. 2005
PubMed ID: 15786443
T to C substitution at -175 or -173 of the gamma-globin promoter affects GATA-1 and Oct-1 binding in vitro differently but can independently reproduce the hereditary persistence of fetal hemoglobin phenotype in transgenic mice.
Liu LR, Du ZW, Zhao HL, Liu XL, Huang XD, Shen J, Ju LM, Fang FD, Zhang JW
J Biol Chem. 2005
PubMed ID: 15613485
Oct-1 and nuclear factor Y bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated mouse GnRH receptor gene transcription.
Kam KY, Jeong KH, Norwitz ER, Jorgensen EM, Kaiser UB
Mol Endocrinol. 2005
PubMed ID: 15388790
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
On the integration of alcohol-related quantitative trait loci and gene expression analyses.
Hitzemann R, Reed C, Malmanger B, Lawler M, Hitzemann B, Cunningham B, McWeeney S, Belknap J, Harrington C, Buck K, Phillips T, Crabbe J
Alcohol Clin Exp Res. 2004
PubMed ID: 15597075
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis.
Ahmed F, Torrado M, Zinovieva RD, Senatorov VV, Wistow G, Tomarev SI
Invest Ophthalmol Vis Sci. 2004
PubMed ID: 15326124
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15302935
Inhibition of HIV-1 TAR RNA-Tat peptide complexation using poly(acrylic acid).
Zhao H, Li J, Jiang L
Biochem Biophys Res Commun. 2004
PubMed ID: 15207707
TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1.
Rave-Harel N, Givens ML, Nelson SB, Duong HA, Coss D, Clark ME, Hall SB, Kamps MP, Mellon PL
J Biol Chem. 2004
PubMed ID: 15138251
Oct-1 maintains an intermediate, stable state of HLA-DRA promoter repression in Rb-defective cells: an Oct-1-containing repressosome that prevents NF-Y binding to the HLA-DRA promoter.
Osborne AR, Zhang H, Fejer G, Palubin KM, Niesen MI, Blanck G
J Biol Chem. 2004
PubMed ID: 15105429
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300.
Molinari S, Relaix F, Lemonnier M, Kirschbaum B, Schäfer B, Buckingham M
Mol Cell Biol. 2004
PubMed ID: 15024082
B cell development and immunoglobulin transcription in Oct-1-deficient mice.
Wang VE, Tantin D, Chen J, Sharp PA
Proc Natl Acad Sci U S A. 2004
PubMed ID: 14762167
Herpes simplex virus infections are arrested in Oct-1-deficient cells.
Nogueira ML, Wang VE, Tantin D, Sharp PA, Kristie TM
Proc Natl Acad Sci U S A. 2004
PubMed ID: 14745036
Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor.
Zhao FQ, Zheng Y, Dong B, Oka T
Gene. 2004
PubMed ID: 14729276
Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice.
Wang VE, Schmidt T, Chen J, Sharp PA, Tantin D
Mol Cell Biol. 2004
PubMed ID: 14729950
Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
Williams DC, Cai M, Clore GM
J Biol Chem. 2004
PubMed ID: 14559893
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
STAT5 and Oct-1 form a stable complex that modulates cyclin D1 expression.
Magné S, Caron S, Charon M, Rouyez MC, Dusanter-Fourt I
Mol Cell Biol. 2003
PubMed ID: 14645506
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
Down-regulation of histone H2B by DNA-dependent protein kinase in response to DNA damage through modulation of octamer transcription factor 1.
Schild-Poulter C, Shih A, Yarymowich NC, Haché RJ
Cancer Res. 2003
PubMed ID: 14612514
p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y.
Hirose T, Sowa Y, Takahashi S, Saito S, Yasuda C, Shindo N, Furuichi K, Sakai T
Oncogene. 2003
PubMed ID: 14586402
STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene.
Lerner L, Henriksen MA, Zhang X, Darnell JE
Genes Dev. 2003
PubMed ID: 14522952
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.
Reményi A, Lins K, Nissen LJ, Reinbold R, Schöler HR, Wilmanns M
Genes Dev. 2003
PubMed ID: 12923055
S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.
Zheng L, Roeder RG, Luo Y
Cell. 2003
PubMed ID: 12887926
Gene switching by metabolic enzymes--how did you get on the invitation list?
McKnight S
Cell. 2003
PubMed ID: 12887915
The regulation of the Oct-1 gene transcription is mediated by two promoters.
Pankratova EV, Sytina EV, Luchina NN, Krivega IV
Immunol Lett. 2003
PubMed ID: 12853155
Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements.
Schaffer A, Kim EC, Wu X, Zan H, Testoni L, Salamon S, Cerutti A, Casali P
J Biol Chem. 2003
PubMed ID: 12672812
A novel transcriptional element which regulates expression of the CYP2D4 gene by Oct-1 and YY-1 binding.
Mizuno D, Takahashi Y, Hiroi T, Imaoka S, Kamataki T, Funae Y
Biochim Biophys Acta. 2003
PubMed ID: 12818430
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
Wysocka J, Herr W
Trends Biochem Sci. 2003
PubMed ID: 12826401
The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development.
Jaegle M, Ghazvini M, Mandemakers W, Piirsoo M, Driegen S, Levavasseur F, Raghoenath S, Grosveld F, Meijer D
Genes Dev. 2003
PubMed ID: 12782656
OBF1 enhances transcriptional potential of Oct1.
Lins K, Reményi A, Tomilin A, Massa S, Wilmanns M, Matthias P, Schöler HR
EMBO J. 2003
PubMed ID: 12727885
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.
Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W
Genes Dev. 2003
PubMed ID: 12670868
Expression of B-lymphocyte-associated transcription factors in human T-cell neoplasms.
Marafioti T, Ascani S, Pulford K, Sabattini E, Piccioli M, Jones M, Zinzani PL, Delsol G, Mason DY, Pileri SA
Am J Pathol. 2003
PubMed ID: 12598320
Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.
Luchina NN, Krivega IV, Pankratova EV
Immunol Lett. 2003
PubMed ID: 12663137
[Regulation of human oct-1 gene transcription involves two promotors]
Zhenilo SV, Deev IE, Serov SM, Polianovskiĭ OL
Genetika. 2003
PubMed ID: 12669425
[Spliced oct-1 gene mRNA isoforms with untranslated exons and a deletion in the region coding for the POU-specific domain]
Deev IE, Zhenilo SV, Polianovskiĭ OL
Mol Biol (Mosk). 2003
PubMed ID: 12624956
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Oct-1 is involved in the transcriptional repression of the gonadotropin-releasing hormone receptor gene.
Cheng CK, Yeung CM, Hoo RL, Chow BK, Leung PC
Endocrinology. 2002
PubMed ID: 12446597
Oct-1 potentiates CREB-driven cyclin D1 promoter activation via a phospho-CREB- and CREB binding protein-independent mechanism.
Boulon S, Dantonel JC, Binet V, Vié A, Blanchard JM, Hipskind RA, Philips A
Mol Cell Biol. 2002
PubMed ID: 12391146
Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.
Matheos D, Ruiz MT, Price GB, Zannis-Hadjopoulos M
Biochim Biophys Acta. 2002
PubMed ID: 12393188
Episodic activation of the rat GnRH promoter: role of the homeoprotein oct-1.
Vazquez-Martinez R, Leclerc GM, Wierman ME, Boockfor FR
Mol Endocrinol. 2002
PubMed ID: 12198245
Involvement of Oct-1 in transcriptional regulation of beta-casein gene expression in mouse mammary gland.
Zhao FQ, Adachi K, Oka T
Biochim Biophys Acta. 2002
PubMed ID: 12151092
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells.
Ortego M, Hernández AG, Bustos C, Blanco-Colio LM, Hernández-Presa MA, Tuñón J, Egido J
Eur J Pharmacol. 2002
PubMed ID: 12144930
Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors.
Gonzalez MM, Carlberg C
J Biol Chem. 2002
PubMed ID: 11891224
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors.
van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D
Hum Mol Genet. 2002
PubMed ID: 12019209
Androgen receptor interactions with Oct-1 and Brn-1 are physically and functionally distinct.
González MI, Tovaglieri A, Robins DM
Mol Cell Endocrinol. 2002
PubMed ID: 11997177
Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1.
Shore P, Dietrich W, Corcoran LM
Nucleic Acids Res. 2002
PubMed ID: 11937630
BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs.
Fan W, Jin S, Tong T, Zhao H, Fan F, Antinore MJ, Rajasekaran B, Wu M, Zhan Q
J Biol Chem. 2002
PubMed ID: 11777930
Crystallization of the Oct-1/SNAP190 peptide/DNA complex.
Hovde S, Brooks A, Strong K, Geiger JH
Acta Crystallogr D Biol Crystallogr. 2002
PubMed ID: 11856838
Tissue-specific isoforms of the ubiquitous transcription factor Oct-1.
Pankratova EV, Deyev IE, Zhenilo SV, Polanovsky OL
Mol Genet Genomics. 2001
PubMed ID: 11683265
Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping.
Reményi A, Tomilin A, Pohl E, Lins K, Philippsen A, Reinbold R, Schöler HR, Wilmanns M
Mol Cell. 2001
PubMed ID: 11583619
Specific localization of transcription factors in the chromatin of mouse mature spermatozoa.
Pittoggi C, Magnano AR, Sciamanna I, Giordano R, Lorenzini R, Spadafora C
Mol Reprod Dev. 2001
PubMed ID: 11550273
Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator.
Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B
Biochemistry. 2001
PubMed ID: 11380252
The binding of Ku antigen to homeodomain proteins promotes their phosphorylation by DNA-dependent protein kinase.
Schild-Poulter C, Pope L, Giffin W, Kochan JC, Ngsee JK, Traykova-Andonova M, Haché RJ
J Biol Chem. 2001
PubMed ID: 11279128
Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressor.
Kakizawa T, Miyamoto T, Ichikawa K, Takeda T, Suzuki S, Mori J, Kumagai M, Yamashita K, Hashizume K
J Biol Chem. 2001
PubMed ID: 11134019
Oct-1 preferentially interacts with androgen receptor in a DNA-dependent manner that facilitates recruitment of SRC-1.
Gonzalez MI, Robins DM
J Biol Chem. 2001
PubMed ID: 11096094
A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.
Ma B, Hernandez N
J Biol Chem. 2001
PubMed ID: 11056176
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels.
Lahbib-Mansais Y, Leroux S, Milan D, Yerle M, Robic A, Jiang Z, André C, Gellin J
Mamm Genome. 2000
PubMed ID: 11130978
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.
Gunther M, Laithier M, Brison O
Mol Cell Biochem. 2000
PubMed ID: 10976766
Octamer transcription factor-1 enhances hepatic nuclear factor-1alpha-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter.
Ishii Y, Hansen AJ, Mackenzie PI
Mol Pharmacol. 2000
PubMed ID: 10779377
Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.
Mahajan SS, Wilson AC
Mol Cell Biol. 2000
PubMed ID: 10629049
Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface.
Chasman D, Cepek K, Sharp PA, Pabo CO
Genes Dev. 1999
PubMed ID: 10541551
Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding.
Wang JM, Préfontaine GG, Lemieux ME, Pope L, Akimenko MA, Haché RJ
Mol Cell Biol. 1999
PubMed ID: 10490647
Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter.
Préfontaine GG, Walther R, Giffin W, Lemieux ME, Pope L, Haché RJ
J Biol Chem. 1999
PubMed ID: 10480874
Genetic and physical mapping of the dreher locus on mouse chromosome 1.
Bergstrom DE, Gagnon LH, Eicher EM
Genomics. 1999
PubMed ID: 10444330
Functional interaction between Oct-1 and retinoid X receptor.
Kakizawa T, Miyamoto T, Ichikawa K, Kaneko A, Suzuki S, Hara M, Nagasawa T, Takeda T, Mori J, Kumagai M, Hashizume K
J Biol Chem. 1999
PubMed ID: 10383413
A QTL for the genetic variance in free-running period and level of locomotor activity between inbred strains of mice.
Mayeda AR, Hofstetter JR
Behav Genet. 1999
PubMed ID: 10547923
POU family transcription factors in the nervous system.
Latchman DS
J Cell Physiol. 1999
PubMed ID: 10199551
Expression of novel alternatively spliced isoforms of the oct-1 transcription factor.
Riss J, Laskov R
Biochim Biophys Acta. 1999
PubMed ID: 10023087
The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropin-releasing hormone distal negative glucocorticoid response element.
Chandran UR, Warren BS, Baumann CT, Hager GL, DeFranco DB
J Biol Chem. 1999
PubMed ID: 9891005
HCF-dependent nuclear import of VP16.
La Boissière S, Hughes T, O'Hare P
EMBO J. 1999
PubMed ID: 9889203
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
High mobility group I/Y protein functions as a specific cofactor for Oct-2A: mapping of interaction domains.
Abdulkadir SA, Casolaro V, Tai AK, Thanos D, Ono SJ
J Leukoc Biol. 1998
PubMed ID: 9823775
Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.
Di Lisi R, Millino C, Calabria E, Altruda F, Schiaffino S, Ausoni S
J Biol Chem. 1998
PubMed ID: 9738004
Recruitment of octamer transcription factors to DNA by glucocorticoid receptor.
Préfontaine GG, Lemieux ME, Giffin W, Schild-Poulter C, Pope L, LaCasse E, Walker P, Haché RJ
Mol Cell Biol. 1998
PubMed ID: 9584182
Oct-1 promoter region contains octamer sites and TAAT motifs recognized by Oct proteins.
Pankratova EV, Polanovsky OL, Polanovasky OL
FEBS Lett. 1998
PubMed ID: 9598983
Adenovirus preterminal protein binds to the CAD enzyme at active sites of viral DNA replication on the nuclear matrix.
Angeletti PC, Engler JA
J Virol. 1998
PubMed ID: 9525610
Interaction of Oct-1 and automodification domain of poly(ADP-ribose) synthetase.
Nie J, Sakamoto S, Song D, Qu Z, Ota K, Taniguchi T
FEBS Lett. 1998
PubMed ID: 9537509
The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1.
Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N
Mol Cell Biol. 1998
PubMed ID: 9418884
The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors.
Inamoto S, Segil N, Pan ZQ, Kimura M, Roeder RG
J Biol Chem. 1997
PubMed ID: 9368058
Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation.
Andersen B, Weinberg WC, Rennekampff O, McEvilly RJ, Bermingham JR, Hooshmand F, Vasilyev V, Hansbrough JF, Pittelkow MR, Yuspa SH, Rosenfeld MG
Genes Dev. 1997
PubMed ID: 9242494
Oct-1, silencer sequence, and GC box regulate thyroid hormone receptor beta1 promoter.
Nagasawa T, Takeda T, Minemura K, DeGroot LJ
Mol Cell Endocrinol. 1997
PubMed ID: 9220031
Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.
Nakano H, Shindo M, Yamada K, Yoshida MC, Santee SM, Ware CF, Jenkins NA, Gilbert DJ, Yagita H, Copeland NC, Okumura K
Genomics. 1997
PubMed ID: 9177772
The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expression.
Ström AC, Forsberg M, Lillhager P, Westin G
Nucleic Acids Res. 1996
PubMed ID: 8668525
Expression of Oct-4 during differentiation of murine F9 cells.
Wang L, Schultz GA
Biochem Cell Biol. 1996
PubMed ID: 8960364
POU homeodomain genes and myogenesis.
Dominov JA, Miller JB
Dev Genet. 1996
PubMed ID: 8900043
Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter.
Kim MH, Peterson DO
J Biol Chem. 1995
PubMed ID: 7499253
The POU homeodomain transcription factor Oct-1 is essential for activity of the gonadotropin-releasing hormone neuron-specific enhancer.
Clark ME, Mellon PL
Mol Cell Biol. 1995
PubMed ID: 7565769
Cloning and mapping of porcine OTF1 extends a synteny group conserved on SSC 4 and HSA 1.
Tuggle CK, Schmitz CB, Wang L, Rothschild MF
Mamm Genome. 1995
PubMed ID: 8535082
Interaction of Oct-1 with TFIIB. Implications for a novel response elicited through the proximal octamer site of the lipoprotein lipase promoter.
Nakshatri H, Nakshatri P, Currie RA
J Biol Chem. 1995
PubMed ID: 7642649
Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics.
Cox M, van Tilborg PJ, de Laat W, Boelens R, van Leeuwen HC, van der Vliet PC, Kaptein R
J Biomol NMR. 1995
PubMed ID: 7663141
Murine collagen intron-binding factor I (CIBF-I) is the same protein as transcription factor Oct-1.
Pogulis RJ, Geddes TJ, Freytag SO
Gene. 1995
PubMed ID: 7607547
Cloning, sequencing and expression of two isoforms of the murine oct-1 transcription factor.
Jaffe J, Hochberg M, Riss J, Hasin T, Reich L, Laskov R
Biochim Biophys Acta. 1995
PubMed ID: 7711063
High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.
Zwilling S, König H, Wirth T
EMBO J. 1995
PubMed ID: 7720710
The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23.
Sturm RA, Eyre HJ, Baker E, Sutherland GR
Cytogenet Cell Genet. 1995
PubMed ID: 7842742
Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer.
Dailey L, Yuan H, Basilico C
Mol Cell Biol. 1994
PubMed ID: 7969117
Lymphotactin: a cytokine that represents a new class of chemokine.
Kelner GS, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ
Science. 1994
PubMed ID: 7973732
The octamer motif present in the Rex-1 promoter binds Oct-1 and Oct-3 expressed by EC cells and ES cells.
Rosfjord E, Rizzino A
Biochem Biophys Res Commun. 1994
PubMed ID: 7945330
Identification of novel single-stranded DNA binding proteins recognizing octamer motif.
Ogawa N, Ariga H, Iguchi-Ariga SM
Biochem Biophys Res Commun. 1994
PubMed ID: 8185580
The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP.
Zwilling S, Annweiler A, Wirth T
Nucleic Acids Res. 1994
PubMed ID: 8202368
Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.
Klemm JD, Rould MA, Aurora R, Herr W, Pabo CO
Cell. 1994
PubMed ID: 8156594
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand.
Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S
Cell. 1994
PubMed ID: 7511063
Targeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strand.
Ohno H, Goto S, Taki S, Shirasawa T, Nakano H, Miyatake S, Aoe T, Ishida Y, Maeda H, Shirai T
EMBO J. 1994
PubMed ID: 8131747
Identification of a marsupial OTF1 gene: cross-species STS analysis and in situ cross-hybridization to Macropus eugenii chromosomes 3/4 and 5.
Sturm RA, Francis DI, Cassady JL, Graves JA
Cytogenet Cell Genet. 1994
PubMed ID: 8258303
Enhanced activation of the human histone H2B promoter by an Oct-1 variant generated by alternative splicing.
Das G, Herr W
J Biol Chem. 1993
PubMed ID: 8227066
In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor.
Jeang KT, Chun R, Lin NH, Gatignol A, Glabe CG, Fan H
J Virol. 1993
PubMed ID: 7690421
CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1.
Lerner A, D'Adamio L, Diener AC, Clayton LK, Reinherz EL
J Immunol. 1993
PubMed ID: 8376772
Chromosomal structure and expression of the human OTF1 locus encoding the Oct-1 protein.
Sturm RA, Cassady JL, Das G, Romo A, Evans GA
Genomics. 1993
PubMed ID: 8314572
Solution structure of the POU-specific DNA-binding domain of Oct-1.
Dekker N, Cox M, Boelens R, Verrijzer CP, van der Vliet PC, Kaptein R
Nature. 1993
PubMed ID: 8479524
The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain.
Assa-Munt N, Mortishire-Smith RJ, Aurora R, Herr W, Wright PE
Cell. 1993
PubMed ID: 8462099
Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16).
Kristie TM, Sharp PA
J Biol Chem. 1993
PubMed ID: 8454622
Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2.
Suzuki N, Peter W, Ciesiolka T, Gruss P, Schöler HR
Nucleic Acids Res. 1993
PubMed ID: 8441632
The POU-domain protein Oct-1 is widely expressed in adult rat organs.
Kambe F, Tsukahara S, Kato T, Seo H
Biochim Biophys Acta. 1993
PubMed ID: 8424955
The DNA binding specificity of the bipartite POU domain and its subdomains.
Verrijzer CP, Alkema MJ, van Weperen WW, Van Leeuwen HC, Strating MJ, van der Vliet PC
EMBO J. 1992
PubMed ID: 1361172
Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma.
Hoopes CW, Taketo M, Ozato K, Liu Q, Howard TA, Linney E, Seldin MF
Genomics. 1992
PubMed ID: 1358808
Construction of a physical map on mouse and human chromosome 1: comparison of 13 Mb of mouse and 11 Mb of human DNA.
Oakey RJ, Watson ML, Seldin MF
Hum Mol Genet. 1992
PubMed ID: 1301170
The nucleotide sequence of mouse OCT-1 cDNA.
Stepchenko AG
Nucleic Acids Res. 1992
PubMed ID: 1561098
Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity.
Segil N, Roberts SB, Heintz N
Science. 1991
PubMed ID: 1684878
Differential phosphorylation of the transcription factor Oct1 during the cell cycle.
Roberts SB, Segil N, Heintz N
Science. 1991
PubMed ID: 1887216
Cloning and sequencing of the rat Oct-1 POU box.
Lillycrop KA, Latchman DS
Nucleic Acids Res. 1991
PubMed ID: 1677182
Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.
Siracusa LD, Rosner MH, Vigano MA, Gilbert DJ, Staudt LM, Copeland NG, Jenkins NA
Genomics. 1991
PubMed ID: 1676977
The gene for the ubiquitous octamer-binding protein Oct-1 is on human chromosome 1, region cen-q32, and near Ly-22 and Ltw-4 on mouse chromosome 1.
Hsieh CL, Sturm R, Herr W, Francke U
Genomics. 1990
PubMed ID: 2341156
New type of POU domain in germ line-specific protein Oct-4.
Schöler HR, Ruppert S, Suzuki N, Chowdhury K, Gruss P
Nature. 1990
PubMed ID: 1690859
Cloning and sequencing of POU-boxes expressed in mouse testis.
Goldsborough A, Ashworth A, Willison K
Nucleic Acids Res. 1990
PubMed ID: 1970171
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells.
Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, Hamada H
Cell. 1990
PubMed ID: 1967980
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
Sturm RA, Das G, Herr W
Genes Dev. 1988
PubMed ID: 2905684

Model Organism Phenotype Links from MGI Top Help

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	Human	Mouse	Rat
Entrez Gene	5451	18986	171068
EnsEMBL Gene(s)	ENSG00000143190	ENSMUSG00000026565	ENSRNOG00000003581
Unigene	Hs.283402	Mm.245261	Rn.46306
Homologene	POU2F1	Pou2f1	Pou2f1
OMIM	164175	N/A	N/A
GeneCards	POU2F1	N/A	N/A
Beta Cell Genomics	DT.100788108 DT.100788111 DT.101983687 DT.312945 DT.92434662	DT.101378934 DT.101378935 DT.101378936 DT.101378937 DT.101378938 DT.101735270 DT.101735272 DT.102557262 DT.110932466 DT.110932468 DT.87050388 DT.87057258 DT.91338642 DT.91338645 DT.91338646	N/A
Reactome	P14859	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	5451	18986	171068

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Interactor	Interactor	Sources	Classification	Pubmed IDs
POU2F1	IRF9	BioGRID	empirical	20211142
POU2F1	HOXB13	BioGRID	empirical	20211142
POU2F1	CEBPE	BioGRID	empirical	20211142
POU2F1	STIP1	BioGRID	empirical	12887926
POU2F1	PRDM5	BioGRID	empirical	20211142
POU2F1	CREB1	BioGRID	empirical	12391146
POU2F1	PARP1	HPRD	empirical	9537509
POU2F1	AES	HPRD	empirical	16002402
POU2F1	ESR1	HPRD, BioGRID	empirical	10480874
POU2F1	FDXR	HPRD	empirical	11096094
POU2F1	XRCC6	HPRD, BioGRID	empirical	12672812 11279128 17213819
POU2F1	POLR1A	BioGRID	empirical	20211142
POU2F1	GAPDH	BioGRID	empirical	12887926
POU2F1	NR3C1	HPRD, BioGRID	empirical	10490647 10480874 9584182 14522952 11096094 20211142
POU2F1	BRD7	BioGRID	empirical	20215511
POU2F1	HCFC1	IntAct, BioGRID	empirical	10629049 9889203 8454622
POU2F1	HDAC1	BioGRID	empirical	19617623
POU2F1	HMGB2	HPRD	empirical	7720710
POU2F1	HMGA1	BioGRID	empirical	9823775
POU2F1	TLX2	BioGRID	empirical	20211142
POU2F1	HOXA6	BioGRID	empirical	20211142
POU2F1	HOXA9	BioGRID	empirical	20211142
POU2F1	HOXB8	BioGRID	empirical	20211142
POU2F1	HOXC4	BioGRID	empirical	20211142
POU2F1	HOXC9	BioGRID	empirical	20211142
POU2F1	AR	HPRD, BioGRID	empirical	10480874 11096094 20211142
POU2F1	LIFR	HPRD	empirical	10383413
POU2F1	LMNB1	BioGRID	empirical	21897860
POU2F1	MNAT1	HPRD, BioGRID	empirical	9368058
POU2F1	MSX1	HPRD	empirical	16002402
POU2F1	NFYA	HPRD	empirical	11777930
POU2F1	NPAT	HPRD, BioGRID	empirical	12887926
POU2F1	PBX1	BioGRID	empirical	15138251
POU2F1	PGR	HPRD, BioGRID	empirical	10480874
POU2F1	PKNOX1	BioGRID	empirical	15138251
POU2F1	POU2AF1	HPRD, BioGRID	empirical	12727885 11380252 10541551 9418884
POU2F1	POU2F1	HPRD, BioGRID	empirical	7720710 11583619 20211142
POU2F1	PRKACA	BioGRID	empirical	1684878
POU2F1	PRKDC	BioGRID	empirical	17213819 14612514
POU2F1	BARD1	HPRD	empirical	11777930
POU2F1	RARA	HPRD, BioGRID	empirical	10480874
POU2F1	RELA	HPRD, BioGRID	empirical	12019209
POU2F1	RXRA	HPRD, BioGRID	empirical	10383413 10480874
POU2F1	SNAPC4	HPRD, BioGRID	empirical	9418884 11856838 11056176
POU2F1	SOX2	HPRD	empirical	14559893
POU2F1	SP1	HPRD, MINT, IntAct, BioGRID	empirical	8668525 9525610 10976766 19070619
POU2F1	BRCA1	HPRD, BioGRID	empirical	11777930 18000219
POU2F1	STAT5A	HPRD	empirical	14645506
POU2F1	STAT5B	HPRD, BioGRID	empirical	14645506 16025120
POU2F1	TBP	HPRD, BioGRID	empirical	8202368
POU2F1	HNF1A	HPRD	empirical	10779377
POU2F1	TEAD1	MINT	empirical	8423815
POU2F1	THRA	HPRD, BioGRID	empirical	10480874
POU2F1	TLE4	HPRD	empirical	16002402
POU2F1	TNF	BioGRID	empirical	12019209
POU2F1	TXNRD1	BioGRID	empirical	10383413
POU2F1	UBC	BioGRID	empirical	21897860 21906983
POU2F1	VDR	BioGRID	empirical	10383413
POU2F1	XRCC5	BioGRID	empirical	11279128 12393188
POU2F1	ZNF143	Reactome	predicted
POU2F1	NCOR2	HPRD	empirical	11134019
POU2F1	CDK11B	BioGRID	empirical	21897860