• About T1DBase
• Regions
  • Human T1D Regions
  • Mouse T1D Regions
    • Linkage Regions
    • Orthologous Regions
  • Rat T1D Regions
    • Linkage Regions
    • Orthologous Regions
    • QTL Regions
• Genome Browser
  • Human GBrowse
  • Mouse GBrowse
  • Rat GBrowse
• Tools
  • Gene Dossier
  • Beta Cell Gene Atlas
  • Batch Query
  • Sequence Search
  • HaemAtlas Search
  • Mouse Strain Search
• Data
  • Poster Pages
  • Downloads
  • Data Submission
• Help
  • FAQ
  • T1DBase Tutorial
• Contact Us

• Page Sections
  • Summary
  • Regions of Interest Overlapping this feature
  • Gene Overview
  • Beta Cell Gene Atlas
  • Tissue Expression
  • HaemAtlas Expression
  • Interactions
  • Cross-Reference to Pathways and GO Terms
  • Publications
  • Model Organism Phenotype Links
  • External Links
  • External resources (dkCOIN)

NCF2

Gene Description:   neutrophil cytosolic factor 2 Synonyms:   Ncf-2, FLJ93058, P67PHOX, NOXA2, Ncf2, p67phox, NCF2, NCF-2, P67-PHOX Orthologs:   Human NCF2 (protein-coding), Mouse Ncf2 (protein-coding), Rat Ncf2 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, KEGG Human-Rat: HomoloGene, MGD, RGD, KEGG Mouse-Rat: HomoloGene, MGD, RGD, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Mouse: 2

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd5.4	Mouse	chr1:77143053..147306684	70.16	608
Idd5.4b	Mouse	chr1:152631809..157938163	5.31	58

(Human) GRCh37 - chr1:183524697..183560056 (35.36 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr1:154654387..154684120 (29.73 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr13:67806516..67834105 (27.59 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas                 no data no data no data no data no data

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for NCF2: The NCF2 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs NCF2   CYBA   HPRD, BioGRID  empirical  11917128  11893732  11248021  11733522  NCF2   CYBB   HPRD  empirical  11917128  11893732  11248021  NCF2   GNAI1   MINT  empirical    NCF2   GNAI2   MINT  empirical    NCF2   GNB1   MINT  empirical    NCF2   NCF4   HPRD, MINT, IntAct, MIPS, BioGRID  empirical  10672014  11893732  11796733  12813044  10486263  11483497  12887891  9064349  9083043  NCF2   PRKDC   BioGRID  empirical  9914162  NCF2   RAC1   HPRD, MINT, IntAct, BioGRID  empirical  11090627  11896062  9624165  9255350  8036496  7738010  9642115  NCF2   RAC2   HPRD, IntAct, BioGRID  empirical  9642115  9624165  11090627  NCF2   ACTB   BioGRID  empirical  11027608  NCF2   S100A8   HPRD  empirical  15642721  NCF2   NCF1   HPRD, MINT, BioGRID  empirical  12169629  9121467  11248021  11893732  11796733  7938008  10486263  11733522  NCF2   SYTL1   HPRD, BioGRID  empirical  11278853  NCF2   PICK1   MIPS  empirical  10623590  NCF2   PRDX6   HPRD  empirical  12121978  NCF2   CDC42   HPRD, MINT, IntAct, BioGRID  empirical  9642115  7738010  11090627

View all

KEGG Network: 4   Leishmaniasis Human - 5140 Mouse - 5140 Rat - 5140 Leukocyte transendothelial migration Human - 4670 Mouse - 4670 Rat - 4670 Osteoclast differentiation Human - 4380 Mouse - 4380 Rat - 4380 Phagosome Human - 4145 Mouse - 4145 Rat - 4145

Biocarta: 2   fMLP induced chemokine gene expression in HMC-1 cells Human Mouse Rac 1 cell motility signaling pathway Human Mouse

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: 1   RAC1 signaling pathway

Gene Ontology: 28   Acrosomal vesicle GO:0001669 Protein binding GO:0005515 Membrane fraction GO:0005624 Nucleolus GO:0005730 Cytoplasm GO:0005737 Superoxide metabolic process GO:0006801 Cellular defense response GO:0006968 Aging GO:0007568 Protein C-terminus binding GO:0008022 Electron carrier activity GO:0009055 Response to glucose stimulus GO:0009749 Response to organic cyclic compound GO:0014070 Response to activity GO:0014823 Superoxide-generating NADPH oxidase activity GO:0016175 Response to lipopolysaccharide GO:0032496 Response to progesterone stimulus GO:0032570 Cellular response to hormone stimulus GO:0032870 Response to lipid GO:0033993 Response to laminar fluid shear stress GO:0034616 Response to drug GO:0042493 Superoxide anion generation GO:0042554 NADPH oxidase complex GO:0043020 Positive regulation of neuron apoptosis GO:0043525 Innate immune response GO:0045087 Respiratory burst GO:0045730 Positive regulation of blood pressure GO:0045777 Rac GTPase binding GO:0048365 Response to hyperoxia GO:0055093

	KEGG Network: 4 Leishmaniasis Human - 5140 Mouse - 5140 Rat - 5140 Leukocyte transendothelial migration Human - 4670 Mouse - 4670 Rat - 4670 Osteoclast differentiation Human - 4380 Mouse - 4380 Rat - 4380 Phagosome Human - 4145 Mouse - 4145 Rat - 4145
	Biocarta: 2 fMLP induced chemokine gene expression in HMC-1 cells Human Mouse Rac 1 cell motility signaling pathway Human Mouse
	Reactome: None available
	NCI-Nature Pathway Interaction Database: 1 RAC1 signaling pathway
	Gene Ontology: 28 Acrosomal vesicle GO:0001669 Protein binding GO:0005515 Membrane fraction GO:0005624 Nucleolus GO:0005730 Cytoplasm GO:0005737 Superoxide metabolic process GO:0006801 Cellular defense response GO:0006968 Aging GO:0007568 Protein C-terminus binding GO:0008022 Electron carrier activity GO:0009055 Response to glucose stimulus GO:0009749 Response to organic cyclic compound GO:0014070 Response to activity GO:0014823 Superoxide-generating NADPH oxidase activity GO:0016175 Response to lipopolysaccharide GO:0032496 Response to progesterone stimulus GO:0032570 Cellular response to hormone stimulus GO:0032870 Response to lipid GO:0033993 Response to laminar fluid shear stress GO:0034616 Response to drug GO:0042493 Superoxide anion generation GO:0042554 NADPH oxidase complex GO:0043020 Positive regulation of neuron apoptosis GO:0043525 Innate immune response GO:0045087 Respiratory burst GO:0045730 Positive regulation of blood pressure GO:0045777 Rac GTPase binding GO:0048365 Response to hyperoxia GO:0055093

Type 1 Diabetes Publications: 1

• Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.
  Wenzel P, Daiber A, Oelze M, Brandt M, Closs E, Xu J, Thum T, Bauersachs J, Ertl G, Zou MH, Förstermann U, Münzel T
  Atherosclerosis. 2008
  PubMed ID: 18061195
   
  

Publications: 151

• Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value.
  Lomnytska MI, Becker S, Bodin I, Olsson A, Hellman K, Hellström AC, Mints M, Hellman U, Auer G, Andersson S
  Br J Cancer. 2011
  PubMed ID: 21119665
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase.
  Maehara Y, Miyano K, Yuzawa S, Akimoto R, Takeya R, Sumimoto H
  J Biol Chem. 2010
  PubMed ID: 20679349
   
  
• Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
  Diabetes Care. 2010
  PubMed ID: 20628086
   
  
• The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population.
  Yu B, Chen Y, Wu Q, Li P, Shao Y, Zhang J, Zhong Q, Peng X, Yang H, Hu X, Chen B, Guan M, Wan J, Zhang W
  Clin Rheumatol. 2010
  PubMed ID: 20842512
   
  
• Polymorphisms in innate immunity genes and risk of childhood leukemia.
  Han S, Lan Q, Park AK, Lee KM, Park SK, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Ahn YO, Chanock SJ, Kim H, Rothman N, Kang D
  Hum Immunol. 2010
  PubMed ID: 20438785
   
  
• Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
  Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
  Pediatr Pulmonol. 2010
  PubMed ID: 20503287
   
  
• Risk of meningioma and common variation in genes related to innate immunity.
  Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD
  Cancer Epidemiol Biomarkers Prev. 2010
  PubMed ID: 20406964
   
  
• PKC delta and NADPH oxidase in retinoic acid-induced neuroblastoma cell differentiation.
  Nitti M, Furfaro AL, Cevasco C, Traverso N, Marinari UM, Pronzato MA, Domenicotti C
  Cell Signal. 2010
  PubMed ID: 20074641
   
  
• Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (second update).
  Roos D, Kuhns DB, Maddalena A, Bustamante J, Kannengiesser C, de Boer M, van Leeuwen K, Köker MY, Wolach B, Roesler J, Malech HL, Holland SM, Gallin JI, Stasia MJ
  Blood Cells Mol Dis. 2010
  PubMed ID: 20167518
   
  
• New genetic associations detected in a host response study to hepatitis B vaccine.
  Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
  Genes Immun. 2010
  PubMed ID: 20237496
   
  
• Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.
  Segat L, Brandão LA, Guimarães RL, Pontillo A, Athanasakis E, de Oliveira RM, Arraes LC, de Lima Filho JL, Crovella S
  Vaccine. 2010
  PubMed ID: 20056178
   
  
• Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling.
  Zhu LH, Wang L, Wang D, Jiang H, Tang QZ, Yan L, Bian ZY, Wang XA, Li H
  Free Radic Biol Med. 2010
  PubMed ID: 19854265
   
  
• Alu-repeat-induced deletions within the NCF2 gene causing p67-phox-deficient chronic granulomatous disease (CGD).
  Gentsch M, Kaczmarczyk A, van Leeuwen K, de Boer M, Kaus-Drobek M, Dagher MC, Kaiser P, Arkwright PD, Gahr M, Rösen-Wolff A, Bochtler M, Secord E, Britto-Williams P, Saifi GM, Maddalena A, Dbaibo G, Bustamante J, Casanova JL, Roos D, Roesler J
  Hum Mutat. 2010
  PubMed ID: 19953534
   
  
• Regulation of NOXO1 Activity through Reversible Interactions with p22 and NOXA1.
  Dutta S, Rittinger K
  PLoS One. 2010
  PubMed ID: 20454568
   
  
• Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
  Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
  Am J Hum Genet. 2009
  PubMed ID: 19913121
   
  
• Effects of acute and chronic endurance exercise on intracellular nitric oxide in putative endothelial progenitor cells: role of NAPDH oxidase.
  Jenkins NT, Witkowski S, Spangenburg EE, Hagberg JM
  Am J Physiol Heart Circ Physiol. 2009
  PubMed ID: 19717732
   
  
• Effect of high-fat diet feeding on hypothalamic redox signaling and central blood pressure regulation.
  Erdos B, Broxson CS, Cudykier I, Basgut B, Whidden M, Landa T, Scarpace PJ, Tümer N
  Hypertens Res. 2009
  PubMed ID: 19713964
   
  
• The domain organization of p67 phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.
  Yuzawa S, Miyano K, Honbou K, Inagaki F, Sumimoto H
  J Innate Immun. 2009
  PubMed ID: 20375610
   
  
• Four different NCF2 mutations in six families from Turkey and an overview of NCF2 gene mutations.
  Köker MY, Sanal O, van Leeuwen K, de Boer M, Metin A, Patiroğlu T, Ozgür TT, Tezcan I, Roos D
  Eur J Clin Invest. 2009
  PubMed ID: 19624736
   
  
• Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
  Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
  Eur Urol. 2009
  PubMed ID: 19692168
   
  
• PTEN identified as important risk factor of chronic obstructive pulmonary disease.
  Hosgood HD, Menashe I, He X, Chanock S, Lan Q
  Respir Med. 2009
  PubMed ID: 19625176
   
  
• Reactive oxygen species are necessary for high flow (shear stress)-induced diameter enlargement of rat resistance arteries.
  Belin de Chantemèle EJ, Vessières E, Dumont O, Guihot AL, Toutain B, Loufrani L, Henrion D
  Microcirculation. 2009
  PubMed ID: 19353375
   
  
• Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
  Bhatti P, Stewart PA, Hutchinson A, Rothman N, Linet MS, Inskip PD, Rajaraman P
  Cancer Epidemiol Biomarkers Prev. 2009
  PubMed ID: 19505917
   
  
• Common variation in genes related to innate immunity and risk of adult glioma.
  Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ
  Cancer Epidemiol Biomarkers Prev. 2009
  PubMed ID: 19423540
   
  
• Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma.
  Han X, Zheng T, Lan Q, Zhang Y, Kilfoy BA, Qin Q, Rothman N, Zahm SH, Holford TR, Leaderer B, Zhang Y
  Cancer Epidemiol Biomarkers Prev. 2009
  PubMed ID: 19423521
   
  
• Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes.
  Sugimura Y, Murase T, Oyama K, Uchida A, Sato N, Hayasaka S, Kano Y, Takagishi Y, Hayashi Y, Oiso Y, Murata Y
  Diabetologia. 2009
  PubMed ID: 19283362
   
  
• Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
  Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
  Environ Mol Mutagen. 2009
  PubMed ID: 19170196
   
  
• Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.
  Lee JY, Park AK, Lee KM, Park SK, Han S, Han W, Noh DY, Yoo KY, Kim H, Welch R, Chanock SJ, Rothman N, Kang D
  Carcinogenesis. 2009
  PubMed ID: 19372141
   
  
• Insulin-induced NADPH oxidase activation promotes proliferation and matrix metalloproteinase activation in monocytes/macrophages.
  San José G, Bidegain J, Robador PA, Díez J, Fortuño A, Zalba G
  Free Radic Biol Med. 2009
  PubMed ID: 19439231
   
  
• Alpha-phenyl-N-tert-butylnitrone attenuates hyperoxia-induced lung injury by down-modulating inflammation in neonatal rats.
  Chang YS, Kim YJ, Yoo HS, Sung DK, Kim SY, Kang S, Park WS
  Exp Lung Res. 2009
  PubMed ID: 19337906
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
  Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R
  Pediatr Infect Dis J. 2009
  PubMed ID: 19258923
   
  
• Role for the first SH3 domain of p67phox in activation of superoxide-producing NADPH oxidases.
  Maehara Y, Miyano K, Sumimoto H
  Biochem Biophys Res Commun. 2009
  PubMed ID: 19116138
   
  
• Differential effects of 17beta-estradiol and of synthetic progestins on aldosterone-salt-induced kidney disease.
  Arias-Loza PA, Muehlfelder M, Elmore SA, Maronpot R, Hu K, Blode H, Hegele-Hartung C, Fritzemeier KH, Ertl G, Pelzer T
  Toxicol Pathol. 2009
  PubMed ID: 19841131
   
  
• Effect of chronic apocynin treatment on nitric oxide and reactive oxygen species production in borderline and spontaneous hypertension.
  Pechánová O, Jendeková L, Vranková S
  Pharmacol Rep. 2009
  PubMed ID: 19307699
   
  
• Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons.
  Coyoy A, Valencia A, Guemez-Gamboa A, Morán J
  Free Radic Biol Med. 2008
  PubMed ID: 18675340
   
  
• Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
  Hosgood HD, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q
  Carcinogenesis. 2008
  PubMed ID: 18676680
   
  
• Molecular epidemiology of chronic granulomatous disease in a series of 80 kindreds: identification of 31 novel mutations.
  Kannengiesser C, Gérard B, El Benna J, Henri D, Kroviarski Y, Chollet-Martin S, Gougerot-Pocidalo MA, Elbim C, Grandchamp B
  Hum Mutat. 2008
  PubMed ID: 18546332
   
  
• Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-beta1-42.
  Zhou J, Zhang S, Zhao X, Wei T
  J Pineal Res. 2008
  PubMed ID: 18298462
   
  
• Focus on FOCIS: the continuing diagnostic challenge of autosomal recessive chronic granulomatous disease.
  Yu G, Hong DK, Dionis KY, Rae J, Heyworth PG, Curnutte JT, Lewis DB
  Clin Immunol. 2008
  PubMed ID: 18625437
   
  
• Sequential binding of cytosolic Phox complex to phagosomes through regulated adaptor proteins: evaluation using the novel monomeric Kusabira-Green System and live imaging of phagocytosis.
  Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N
  J Immunol. 2008
  PubMed ID: 18566430
   
  
• Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
  Lemarie A, Bourdonnay E, Morzadec C, Fardel O, Vernhet L
  J Immunol. 2008
  PubMed ID: 18424721
   
  
• Age-related alterations in reactivity of cerebral arterioles: role of oxidative stress.
  Mayhan WG, Arrick DM, Sharpe GM, Sun H
  Microcirculation. 2008
  PubMed ID: 18386218
   
  
• Toward a confocal subcellular atlas of the human proteome.
  Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
  Mol Cell Proteomics. 2008
  PubMed ID: 18029348
   
  
• New polymorphism in the NCF-2 gene leading to alternative splicing without altering gene expression or the respiratory burst activity.
  Gómez LA, Rugeles MT, Patiño PJ, Condino Neto A
  Am J Hematol. 2008
  PubMed ID: 17910042
   
  
• Phosphatidylinositol 3-phosphate-dependent and -independent functions of p40phox in activation of the neutrophil NADPH oxidase.
  Bissonnette SA, Glazier CM, Stewart MQ, Brown GE, Ellson CD, Yaffe MB
  J Biol Chem. 2008
  PubMed ID: 18029359
   
  
• A single nucleotide polymorphism in the promoter region of theNCF-2 gene.
  Gómez LA, Patiño PJ, Novaira HJ, Morales MM, Condino-Neto A
  Am J Hematol. 2007
  PubMed ID: 17712795
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
  Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B
  J Infect Dis. 2007
  PubMed ID: 17703412
   
  
• Cytotoxicity of paraquat in microglial cells: Involvement of PKCdelta- and ERK1/2-dependent NADPH oxidase.
  Miller RL, Sun GY, Sun AY
  Brain Res. 2007
  PubMed ID: 17662968
   
  
• Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha.
  Gauss KA, Nelson-Overton LK, Siemsen DW, Gao Y, DeLeo FR, Quinn MT
  J Leukoc Biol. 2007
  PubMed ID: 17537988
   
  
• Flow-induced remodeling in resistance arteries from obese Zucker rats is associated with endothelial dysfunction.
  Bouvet C, Belin de Chantemèle E, Guihot AL, Vessières E, Bocquet A, Dumont O, Jardel A, Loufrani L, Moreau P, Henrion D
  Hypertension. 2007
  PubMed ID: 17515452
   
  
• Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity.
  Ammons MC, Siemsen DW, Nelson-Overton LK, Quinn MT, Gauss KA
  J Biol Chem. 2007
  PubMed ID: 17462995
   
  
• NADPH oxidase- and mitochondrion-derived superoxide at rostral ventrolateral medulla in endotoxin-induced cardiovascular depression.
  Sheh YL, Hsu C, Chan SH, Chan JY
  Free Radic Biol Med. 2007
  PubMed ID: 17448908
   
  
• Exercise training raises expression of the cytosolic components of NADPH oxidase in rat neutrophils.
  Levada-Pires AC, Lambertucci RH, Mohamad M, Hirabara SM, Curi R, Pithon-Curi TC
  Eur J Appl Physiol. 2007
  PubMed ID: 17310390
   
  
• [Increased expression of NADPH oxidase p47-PHOX and p67-PHOX factor in idiopathic pulmonary fibrosis]
  Wang CL, Kang J, Li ZH
  Zhonghua Jie He He Hu Xi Za Zhi. 2007
  PubMed ID: 17651608
   
  
• Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine.
  Guo Z, Xia Z, Jiang J, McNeill JH
  Am J Physiol Heart Circ Physiol. 2007
  PubMed ID: 17122189
   
  
• Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes.
  Kawahara T, Quinn MT, Lambeth JD
  BMC Evol Biol. 2007
  PubMed ID: 17612411
   
  
• The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.
  Ming W, Li S, Billadeau DD, Quilliam LA, Dinauer MC
  Mol Cell Biol. 2007
  PubMed ID: 17060455
   
  
• Single-cell optical imaging of the phagocyte NADPH oxidase.
  van Manen HJ, van Bruggen R, Roos D, Otto C
  Antioxid Redox Signal. 2006
  PubMed ID: 16987007
   
  
• Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cbeta activation.
  Siow YL, Au-Yeung KK, Woo CW, O K
  Biochem J. 2006
  PubMed ID: 16626305
   
  
• Sequencing, expression, and functional analyses support the candidacy of Ncf2 in susceptibility to Salmonella typhimurium infection in wild-derived mice.
  Sancho-Shimizu V, Malo D
  J Immunol. 2006
  PubMed ID: 16709856
   
  
• The DNA sequence and biological annotation of human chromosome 1.
  Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E
  Nature. 2006
  PubMed ID: 16710414
   
  
• Coronary artery superoxide production and nox isoform expression in human coronary artery disease.
  Guzik TJ, Sadowski J, Guzik B, Jopek A, Kapelak B, Przybylowski P, Wierzbicki K, Korbut R, Harrison DG, Channon KM
  Arterioscler Thromb Vasc Biol. 2006
  PubMed ID: 16293794
   
  
• Variants of the 5'-untranslated region of human NCF2: expression and translational efficiency.
  Gauss KA, Bunger PL, Crawford MA, McDermott BE, Swearingen R, Nelson-Overton LK, Siemsen DW, Kobayashi SD, Deleo FR, Quinn MT
  Gene. 2006
  PubMed ID: 16310324
   
  
• Genetic and mutational heterogeneity of autosomal recessive chronic granulomatous disease in Tunisia.
  El Kares R, Barbouche MR, Elloumi-Zghal H, Bejaoui M, Chemli J, Mellouli F, Tebib N, Abdelmoula MS, Boukthir S, Fitouri Z, M'Rad S, Bouslama K, Touiri H, Abdelhak S, Dellagi MK
  J Hum Genet. 2006
  PubMed ID: 16937026
   
  
• Genetic polymorphisms and susceptibility to lung disease.
  Lee PL, West C, Crain K, Wang L
  J Negat Results Biomed. 2006
  PubMed ID: 16608528
   
  
• Ensembl 2006.
  Birney E, Andrews D, Caccamo M, Chen Y, Clarke L, Coates G, Cox T, Cunningham F, Curwen V, Cutts T, Down T, Durbin R, Fernandez-Suarez XM, Flicek P, Gräf S, Hammond M, Herrero J, Howe K, Iyer V, Jekosch K, Kähäri A, Kasprzyk A, Keefe D, Kokocinski F, Kulesha E, London D, Longden I, Melsopp C, Meidl P, Overduin B, Parker A, Proctor G, Prlic A, Rae M, Rios D, Redmond S, Schuster M, Sealy I, Searle S, Severin J, Slater G, Smedley D, Smith J, Stabenau A, Stalker J, Trevanion S, Ureta-Vidal A, Vogel J, White S, Woodwark C, Hubbard TJ
  Nucleic Acids Res. 2006
  PubMed ID: 16381931
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox.
  Mizuki K, Takeya R, Kuribayashi F, Nobuhisa I, Kohda D, Nunoi H, Takeshige K, Sumimoto H
  Arch Biochem Biophys. 2005
  PubMed ID: 16297854
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• Identification of non-mitochondrial NADPH oxidase and the spatio-temporal organization of its components in mouse spermatozoa.
  Shukla S, Jha RK, Laloraya M, Kumar PG
  Biochem Biophys Res Commun. 2005
  PubMed ID: 15850784
   
  
• Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways.
  Carstanjen D, Yamauchi A, Koornneef A, Zang H, Filippi MD, Harris C, Towe J, Atkinson S, Zheng Y, Dinauer MC, Williams DA
  J Immunol. 2005
  PubMed ID: 15814684
   
  
• Localization of NADPH oxidase subunits in neonatal sympathetic neurons.
  Hilburger EW, Conte EJ, McGee DW, Tammariello SP
  Neurosci Lett. 2005
  PubMed ID: 15722179
   
  
• The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.
  Kerkhoff C, Nacken W, Benedyk M, Dagher MC, Sopalla C, Doussiere J
  FASEB J. 2005
  PubMed ID: 15642721
   
  
• Identification of a novel tumor necrosis factor alpha-responsive region in the NCF2 promoter.
  Gauss KA, Bunger PL, Larson TC, Young CJ, Nelson-Overton LK, Siemsen DW, Quinn MT
  J Leukoc Biol. 2005
  PubMed ID: 15513967
   
  
• Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage.
  Patel M, Li QY, Chang LY, Crapo J, Liang LP
  J Neurochem. 2005
  PubMed ID: 15606902
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
  Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S
  Genome Res. 2004
  PubMed ID: 15342556
   
  
• Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.
  Guzik TJ, Sadowski J, Kapelak B, Jopek A, Rudzinski P, Pillai R, Korbut R, Channon KM
  Arterioscler Thromb Vasc Biol. 2004
  PubMed ID: 15256399
   
  
• Nox3 regulation by NOXO1, p47phox, and p67phox.
  Cheng G, Ritsick D, Lambeth JD
  J Biol Chem. 2004
  PubMed ID: 15181005
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
  PubMed ID: 15057822
   
  
• NAD(P)H oxidase, superoxide dismutase, catalase, glutathione peroxidase and nitric oxide synthase expression in subacute spinal cord injury.
  Vaziri ND, Lee YS, Lin CY, Lin VW, Sindhu RK
  Brain Res. 2004
  PubMed ID: 14644473
   
  
• Complete sequencing and characterization of 21,243 full-length human cDNAs.
  Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
  Nat Genet. 2004
  PubMed ID: 14702039
   
  
• Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
  Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 14610273
   
  
• Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy.
  Kitada M, Koya D, Sugimoto T, Isono M, Araki S, Kashiwagi A, Haneda M
  Diabetes. 2003
  PubMed ID: 14514646
   
  
• Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.
  Lamark T, Perander M, Outzen H, Kristiansen K, Øvervatn A, Michaelsen E, Bjørkøy G, Johansen T
  J Biol Chem. 2003
  PubMed ID: 12813044
   
  
• Changing the conformation state of cytochrome b558 initiates NADPH oxidase activation: MRP8/MRP14 regulation.
  Berthier S, Paclet MH, Lerouge S, Roux F, Vergnaud S, Coleman AW, Morel F
  J Biol Chem. 2003
  PubMed ID: 12719414
   
  
• Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases.
  Takeya R, Ueno N, Kami K, Taura M, Kohjima M, Izaki T, Nunoi H, Sumimoto H
  J Biol Chem. 2003
  PubMed ID: 12716910
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity.
  Leavey PJ, Gonzalez-Aller C, Thurman G, Kleinberg M, Rinckel L, Ambruso DW, Freeman S, Kuypers FA, Ambruso DR
  J Biol Chem. 2002
  PubMed ID: 12121978
   
  
• Expression of a p67(phox) homolog in Caco-2 cells giving O(2)(-)-reconstituting ability to cytochrome b(558) together with recombinant p47(phox).
  Yoshida L, Nishida S, Shimoyama T, Kawahara T, Rokutan K, Tsunawaki S
  Biochem Biophys Res Commun. 2002
  PubMed ID: 12207919
   
  
• Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.
  Kami K, Takeya R, Sumimoto H, Kohda D
  EMBO J. 2002
  PubMed ID: 12169629
   
  
• NAD(P)H oxidase-dependent platelet superoxide anion release increases platelet recruitment.
  Krötz F, Sohn HY, Gloe T, Zahler S, Riexinger T, Schiele TM, Becker BF, Theisen K, Klauss V, Pohl U
  Blood. 2002
  PubMed ID: 12130503
   
  
• Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox).
  Zhao X, Bey EA, Wientjes FB, Cathcart MK
  J Biol Chem. 2002
  PubMed ID: 12101222
   
  
• Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells.
  Li JM, Shah AM
  J Biol Chem. 2002
  PubMed ID: 11893732
   
  
• A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism.
  Gorzalczany Y, Alloul N, Sigal N, Weinbaum C, Pick E
  J Biol Chem. 2002
  PubMed ID: 11896062
   
  
• Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system.
  Price MO, McPhail LC, Lambeth JD, Han CH, Knaus UG, Dinauer MC
  Blood. 2002
  PubMed ID: 11929750
   
  
• Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558 II.
  Dang PM, Cross AR, Quinn MT, Babior BM
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 11917128
   
  
• Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox.
  Lapouge K, Smith SJ, Groemping Y, Rittinger K
  J Biol Chem. 2002
  PubMed ID: 11796733
   
  
• Mapping of functional domains in the p22(phox) subunit of flavocytochrome b(559) participating in the assembly of the NADPH oxidase complex by "peptide walking".
  Dahan I, Issaeva I, Gorzalczany Y, Sigal N, Hirshberg M, Pick E
  J Biol Chem. 2002
  PubMed ID: 11733522
   
  
• Cloning and sequencing of rabbit leukocyte NADPH oxidase genes reveals a unique p67(phox) homolog.
  Gauss KA, Mascolo PL, Siemsen DW, Nelson LK, Bunger PL, Pagano PJ, Quinn MT
  J Leukoc Biol. 2002
  PubMed ID: 11818454
   
  
• AP-1 is essential for p67(phox) promoter activity.
  Gauss KA, Bunger PL, Quinn MT
  J Leukoc Biol. 2002
  PubMed ID: 11781392
   
  
• A fusion protein between rac and p67phox (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components.
  Miyano K, Ogasawara S, Han CH, Fukuda H, Tamura M
  Biochemistry. 2001
  PubMed ID: 11705402
   
  
• Transcriptional regulation of the p67phox gene: role of AP-1 in concert with myeloid-specific transcription factors.
  Li SL, Valente AJ, Wang L, Gamez MJ, Clark RA
  J Biol Chem. 2001
  PubMed ID: 11483614
   
  
• Genetic influences on the end-stage effector phase of arthritis.
  Ji H, Gauguier D, Ohmura K, Gonzalez A, Duchatelle V, Danoy P, Garchon HJ, Degott C, Lathrop M, Benoist C, Mathis D
  J Exp Med. 2001
  PubMed ID: 11489951
   
  
• Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions.
  Ito T, Matsui Y, Ago T, Ota K, Sumimoto H
  EMBO J. 2001
  PubMed ID: 11483497
   
  
• JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase.
  McAdara Berkowitz JK, Catz SD, Johnson JL, Ruedi JM, Thon V, Babior BM
  J Biol Chem. 2001
  PubMed ID: 11278853
   
  
• Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558.
  Dang PM, Cross AR, Babior BM
  Proc Natl Acad Sci U S A. 2001
  PubMed ID: 11248021
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice.
  Mitsos LM, Cardon LR, Fortin A, Ryan L, LaCourse R, North RJ, Gros P
  Genes Immun. 2000
  PubMed ID: 11197687
   
  
• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
  Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
  Genome Res. 2000
  PubMed ID: 11076861
   
  
• Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase.
  Tamura M, Kai T, Tsunawaki S, Lambeth JD, Kameda K
  Biochem Biophys Res Commun. 2000
  PubMed ID: 11027608
   
  
• Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (first update).
  Cross AR, Noack D, Rae J, Curnutte JT, Heyworth PG
  Blood Cells Mol Dis. 2000
  PubMed ID: 11112388
   
  
• Structure of the TPR domain of p67phox in complex with Rac.GTP.
  Lapouge K, Smith SJ, Walker PA, Gamblin SJ, Smerdon SJ, Rittinger K
  Mol Cell. 2000
  PubMed ID: 11090627
   
  
• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
  Genome Res. 2000
  PubMed ID: 11042159
   
  
• Activation of NADPH oxidase in Alzheimer's disease brains.
  Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, Hayakawa T, Nunomura A, Chiba S, Perry G, Smith MA, Fujimoto S
  Biochem Biophys Res Commun. 2000
  PubMed ID: 10873554
   
  
• Complementation of NADPH oxidase in p67-phox-deficient CGD patients p67-phox/p40-phox interaction.
  Vergnaud S, Paclet MH, El Benna J, Pocidalo MA, Morel F
  Eur J Biochem. 2000
  PubMed ID: 10672014
   
  
• Cloning and expression of bovine p47-phox and p67-phox: comparison with the human and murine homologs.
  Bunger PL, Swain SD, Clements MK, Siemsen DW, Davis AR, Gauss KA, Quinn MT
  J Leukoc Biol. 2000
  PubMed ID: 10647999
   
  
• Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase.
  Noack D, Rae J, Cross AR, Muñoz J, Salmen S, Mendoza JA, Rossi N, Curnutte JT, Heyworth PG
  Hum Genet. 1999
  PubMed ID: 10598813
   
  
• Molecular characterization of autosomal recessive chronic granulomatous disease caused by a defect of the nicotinamide adenine dinucleotide phosphate (reduced form) oxidase component p67-phox.
  Patiño PJ, Rae J, Noack D, Erickson R, Ding J, de Olarte DG, Curnutte JT
  Blood. 1999
  PubMed ID: 10498624
   
  
• Rac1 disrupts p67phox/p40phox binding: a novel role for Rac in NADPH oxidase activation.
  Rinckel LA, Faris SL, Hitt ND, Kleinberg ME
  Biochem Biophys Res Commun. 1999
  PubMed ID: 10486263
   
  
• Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase.
  Koga H, Terasawa H, Nunoi H, Takeshige K, Inagaki F, Sumimoto H
  J Biol Chem. 1999
  PubMed ID: 10455184
   
  
• Developmental expression of NADPH phagocytic oxidase components in mouse embryos.
  Baehner RL, Millar-Groff S, Bringas P
  Pediatr Res. 1999
  PubMed ID: 10447107
   
  
• The Ku70 autoantigen interacts with p40phox in B lymphocytes.
  Grandvaux N, Grizot S, Vignais PV, Dagher MC
  J Cell Sci. 1999
  PubMed ID: 9914162
   
  
• High-efficiency full-length cDNA cloning.
  Carninci P, Hayashizaki Y
  Methods Enzymol. 1999
  PubMed ID: 10349636
   
  
• Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox).
  Ahmed S, Prigmore E, Govind S, Veryard C, Kozma R, Wientjes FB, Segal AW, Lim L
  J Biol Chem. 1998
  PubMed ID: 9624165
   
  
• Phagocyte NADPH oxidase p67-phox possesses a novel carboxylterminal binding site for the GTPases Rac2 and Cdc42.
  Faris SL, Rinckel LA, Huang J, Hong YR, Kleinberg ME
  Biochem Biophys Res Commun. 1998
  PubMed ID: 9642115
   
  
• Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.
  Mizuki K, Kadomatsu K, Hata K, Ito T, Fan QW, Kage Y, Fukumaki Y, Sakaki Y, Takeshige K, Sumimoto H
  Eur J Biochem. 1998
  PubMed ID: 9490028
   
  
• Cytosolic phox proteins interact with and regulate the assembly of coronin in neutrophils.
  Grogan A, Reeves E, Keep N, Wientjes F, Totty NF, Burlingame AL, Hsuan JJ, Segal AW
  J Cell Sci. 1997
  PubMed ID: 9365277
   
  
• Elevated expression of p47phox and p67phox proteins in neutrophils from burned rats.
  Fazal N, Sabeh F, Gamelli RL, Sayeed MM
  Shock. 1997
  PubMed ID: 9329126
   
  
• p40(phox) down-regulates NADPH oxidase activity through interactions with its SH3 domain.
  Sathyamoorthy M, de Mendez I, Adams AG, Leto TL
  J Biol Chem. 1997
  PubMed ID: 9083043
   
  
• Specificity of p47phox SH3 domain interactions in NADPH oxidase assembly and activation.
  de Mendez I, Homayounpour N, Leto TL
  Mol Cell Biol. 1997
  PubMed ID: 9121467
   
  
• Identification of a double mutation (D160V-K161E) in the p67phox gene of a chronic granulomatous disease patient.
  Bonizzato A, Russo MP, Donini M, Dusi S
  Biochem Biophys Res Commun. 1997
  PubMed ID: 9070911
   
  
• [Signal transduction by Rac small G proteins in phagocytes]
  Dorseuil O, Gacon G
  C R Seances Soc Biol Fil. 1997
  PubMed ID: 9255350
   
  
• Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins.
  DeLeo FR, Quinn MT
  J Leukoc Biol. 1996
  PubMed ID: 8975869
   
  
• Normalization and subtraction: two approaches to facilitate gene discovery.
  Bonaldo MF, Lennon G, Soares MB
  Genome Res. 1996
  PubMed ID: 8889548
   
  
• NADPH oxidase and the respiratory burst.
  Wientjes FB, Segal AW
  Semin Cell Biol. 1995
  PubMed ID: 8748143
   
  
• A 68-kDa kinase and NADPH oxidase component p67phox are targets for Cdc42Hs and Rac1 in neutrophils.
  Prigmore E, Ahmed S, Best A, Kozma R, Manser E, Segal AW, Lim L
  J Biol Chem. 1995
  PubMed ID: 7738010
   
  
• Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.
  Leto TL, Adams AG, de Mendez I
  Proc Natl Acad Sci U S A. 1994
  PubMed ID: 7938008
   
  
• Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity.
  Diekmann D, Abo A, Johnston C, Segal AW, Hall A
  Science. 1994
  PubMed ID: 8036496
   
  
• Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers.
  de Boer M, Hilarius-Stokman PM, Hossle JP, Verhoeven AJ, Graf N, Kenney RT, Seger R, Roos D
  Blood. 1994
  PubMed ID: 8286749
   
  
• Cloning and functional expression of the mouse homologue of p47phox.
  Jackson SH, Malech HL, Kozak CA, Lomax KJ, Gallin JI, Holland SM
  Immunogenetics. 1994
  PubMed ID: 8119734
   
  
• Characterization of the p67phox gene: genomic organization and restriction fragment length polymorphism analysis for prenatal diagnosis in chronic granulomatous disease.
  Kenney RT, Malech HL, Epstein ND, Roberts RL, Leto TL
  Blood. 1993
  PubMed ID: 7903171
   
  
• Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the translocation of cytosolic p67phox.
  Dusi S, Rossi F
  Biochem J. 1993
  PubMed ID: 8257426
   
  
• The GTPase dynamin binds to and is activated by a subset of SH3 domains.
  Gout I, Dhand R, Hiles ID, Fry MJ, Panayotou G, Das P, Truong O, Totty NF, Hsuan J, Booker GW
  Cell. 1993
  PubMed ID: 8402898
   
  
• A HindIII polymorphism in the human NCF2 gene.
  Kenney RT, Leto TL
  Nucleic Acids Res. 1990
  PubMed ID: 1979859
   
  
• Genes for two autosomal recessive forms of chronic granulomatous disease assigned to 1q25 (NCF2) and 7q11.23 (NCF1).
  Francke U, Hsieh CL, Foellmer BE, Lomax KJ, Malech HL, Leto TL
  Am J Hum Genet. 1990
  PubMed ID: 2393022
   
  
• Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src.
  Leto TL, Lomax KJ, Volpp BD, Nunoi H, Sechler JM, Nauseef WM, Clark RA, Gallin JI, Malech HL
  Science. 1990
  PubMed ID: 1692159
   
  
• New human transforming genes detected by a tumorigenicity assay.
  Fasano O, Birnbaum D, Edlund L, Fogh J, Wigler M
  Mol Cell Biol. 1984
  PubMed ID: 6092933
   
  

Relevant resources:

Comment on this Page
Privacy Statement  |   Copyright, Warranty & Disclaimer  |   Contact Us
Copyright © 2001-2011, T1DBase | Version 4.8 | PMID:20937630
Printed on Fri February 10, 2012