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LTF

Gene Description:   lactotransferrin Synonyms:   LTF, Ltf, HLF2, GIG12, Ms10r, Csp82, LF, MMS10R, Lf Orthologs:   Human LTF (protein-coding), Mouse Ltf (protein-coding), Rat Ltf (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid Human-Rat: HomoloGene, MGD, RGD Mouse-Rat: HomoloGene, MGD, RGD Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1 Rat: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
3p21.31	Human	chr3:45980673..46654132	0.67	77	rs333 rs11711054

Other Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Human 3p21.31 Orthologous Region	Rat	chr8:115324105..115463724	0.14	7
Human 3p21.31 Orthologous Region	Mouse	chr9:110823597..110967895	0.14	5

(Human) GRCh37 - chr3:46477136..46526724 (49.59 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr9:110921796..110945270 (23.47 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr8:115417764..115440609 (22.84 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas                 no data no data no data no data no data

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for LTF: The LTF interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs LTF   CEL   HPRD  empirical  3995055  LTF   IKBIP   IntAct  empirical  20360068  LTF   CP   HPRD, BioGRID  empirical  10666301  LTF   LCN1   HPRD  empirical  10558865  LTF   LRP1   HPRD  empirical  1464627  LTF   LYZ   HPRD, BioGRID  empirical  9359845  LTF   MUC7   HPRD, BioGRID  empirical  12766201  LTF   ITLN1   HPRD  empirical  11313366  LTF   SGK1   IntAct, BioGRID  empirical  17353931  LTF   CALM1   HPRD  empirical  1544444  LTF   CDK5RAP3   IntAct  empirical  17353931  LTF   DYNLL1   IntAct  empirical  20360068  LTF   CD14   HPRD, BioGRID  empirical  11083760

View all

KEGG Network: None available   None available.

Biocarta: 1   Anthrax Toxin Mechanism of Action Human

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 15   Serine-type endopeptidase activity GO:0004252 Protein binding GO:0005515 Extracellular region GO:0005576 Cytoplasm GO:0005737 Proteolysis GO:0006508 Ion transport GO:0006811 Iron ion transport GO:0006826 Cellular iron ion homeostasis GO:0006879 Humoral immune response GO:0006959 Ferric iron binding GO:0008199 Heparin binding GO:0008201 Peptidase activity GO:0008233 Stored secretory granule GO:0030141 Defense response to bacterium GO:0042742 Metal ion binding GO:0046872

	KEGG Network: None available
	Biocarta: 1 Anthrax Toxin Mechanism of Action Human
	Reactome: None available
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 15 Serine-type endopeptidase activity GO:0004252 Protein binding GO:0005515 Extracellular region GO:0005576 Cytoplasm GO:0005737 Proteolysis GO:0006508 Ion transport GO:0006811 Iron ion transport GO:0006826 Cellular iron ion homeostasis GO:0006879 Humoral immune response GO:0006959 Ferric iron binding GO:0008199 Heparin binding GO:0008201 Peptidase activity GO:0008233 Stored secretory granule GO:0030141 Defense response to bacterium GO:0042742 Metal ion binding GO:0046872

Type 1 Diabetes Publications: 1

• High prevalence of autoantibodies against carbonic anhydrase II and lactoferrin in type 1 diabetes: concept of autoimmune exocrinopathy and endocrinopathy of the pancreas.
  Taniguchi T, Okazaki K, Okamoto M, Seko S, Tanaka J, Uchida K, Nagashima K, Kurose T, Yamada Y, Chiba T, Seino Y
  Pancreas. 2003
  PubMed ID: 12826902
   
  

Publications: 222

• Does lactoferrin behave as an immunohistochemical oncofetal marker in bone and cartilage human neoplasms?
  Ieni A, Barresi V, Grosso M, Speciale G, Rosa MA, Tuccari G
  Pathol Oncol Res. 2011
  PubMed ID: 20972893
   
  
• Genome-wide association study implicates PARD3B-based AIDS restriction.
  Troyer JL, Nelson GW, Lautenberger JA, Chinn L, McIntosh C, Johnson RC, Sezgin E, Kessing B, Malasky M, Hendrickson SL, Li G, Pontius J, Tang M, An P, Winkler CA, Limou S, Le Clerc S, Delaneau O, Zagury JF, Schuitemaker H, van Manen D, Bream JH, Gomperts ED, Buchbinder S, Goedert JJ, Kirk GD, O'Brien SJ
  J Infect Dis. 2011
  PubMed ID: 21502085
   
  
• Recognition roles of the carbohydrate glycotopes of human and bovine lactoferrins in lectin-N-glycan interactions.
  Yen MH, Wu AM, Yang Z, Gong YP, Chang ET
  Biochim Biophys Acta. 2011
  PubMed ID: 21055448
   
  
• Multiplex immunoassay of lower genital tract mucosal fluid from women attending an urban STD clinic shows broadly increased IL1ß and lactoferrin.
  Spear GT, Kendrick SR, Chen HY, Thomas TT, Bahk M, Balderas R, Ghosh S, Weinberg A, Landay AL
  PLoS One. 2011
  PubMed ID: 21572958
   
  
• Initial characterization of the human central proteome.
  Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
  BMC Syst Biol. 2011
  PubMed ID: 21269460
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Relationships among salivary immunoglobulin A, lactoferrin and cortisol in basketball players during a basketball season.
  He CS, Tsai ML, Ko MH, Chang CK, Fang SH
  Eur J Appl Physiol. 2010
  PubMed ID: 20668874
   
  
• A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
  Romero R, Friel LA, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, Bartlett J, Salisbury BA, Anant MK, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
  Am J Obstet Gynecol. 2010
  PubMed ID: 20673868
   
  
• Lactoferrin is a novel predictor of fatal ischemic heart disease in diabetes mellitus type 2: long-term follow-up of the HUNT 1 study.
  Vengen IT, Dale AC, Wiseth R, Midthjell K, Videm V
  Atherosclerosis. 2010
  PubMed ID: 20598696
   
  
• Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
  Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Tevfik Dorak M
  Mol Hum Reprod. 2010
  PubMed ID: 20587610
   
  
• Deposition of lactoferrin in fibrillar-type senile plaques in the brains of transgenic mouse models of Alzheimer's disease.
  Wang L, Sato H, Zhao S, Tooyama I
  Neurosci Lett. 2010
  PubMed ID: 20599473
   
  
• Faecal lactoferrin, capsule endoscopy and Crohn's disease. Is there a three way relationship? A pilot study.
  Sidhu R, Sanders DS, Wilson P, Foye L, Morley S, McAlindon ME
  J Gastrointestin Liver Dis. 2010
  PubMed ID: 20922188
   
  
• Clinical utility of calprotectin and lactoferrin as markers of inflammation in patients with inflammatory bowel disease.
  Caccaro R, D'Incá R, Sturniolo GC
  Expert Rev Clin Immunol. 2010
  PubMed ID: 20594128
   
  
• Positive selection drives lactoferrin evolution in mammals.
  Liang GM, Jiang XP
  Genetica. 2010
  PubMed ID: 20401683
   
  
• Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
  Mol Med. 2010
  PubMed ID: 20379614
   
  
• O-GlcNAcylation/phosphorylation cycling at Ser10 controls both transcriptional activity and stability of delta-lactoferrin.
  Hardivillé S, Hoedt E, Mariller C, Benaïssa M, Pierce A
  J Biol Chem. 2010
  PubMed ID: 20404350
   
  
• Charge reversal by salt-induced aggregation in aqueous lactoferrin solutions.
  Mela I, Aumaitre E, Williamson AM, Yakubov GE
  Colloids Surf B Biointerfaces. 2010
  PubMed ID: 20207115
   
  
• Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
  Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
  Pediatr Pulmonol. 2010
  PubMed ID: 20503287
   
  
• E2F1-directed activation of Bcl-2 is correlated with lactoferrin-induced apoptosis in Jurkat leukemia T lymphocytes.
  Lee SH, Hwang HM, Pyo CW, Hahm DH, Choi SY
  Biometals. 2010
  PubMed ID: 20411301
   
  
• Periodontitis, periodontopathic bacteria and lactoferrin.
  Wakabayashi H, Kondo I, Kobayashi T, Yamauchi K, Toida T, Iwatsuki K, Yoshie H
  Biometals. 2010
  PubMed ID: 20155438
   
  
• Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.
  Romero R, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Chaiworapongsa T, Pearce BD, Friel LA, Bartlett J, Anant MK, Salisbury BA, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
  Am J Obstet Gynecol. 2010
  PubMed ID: 20452482
   
  
• Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling.
  Ando K, Hasegawa K, Shindo K, Furusawa T, Fujino T, Kikugawa K, Nakano H, Takeuchi O, Akira S, Akiyama T, Gohda J, Inoue J, Hayakawa M
  FEBS J. 2010
  PubMed ID: 20345905
   
  
• New genetic associations detected in a host response study to hepatitis B vaccine.
  Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
  Genes Immun. 2010
  PubMed ID: 20237496
   
  
• Analysis of the association between lactotransferrin (LTF) gene polymorphism and dental caries.
  Azevedo LF, Pecharki GD, Brancher JA, Cordeiro CA, Medeiros KG, Antunes AA, Arruda ES, Werneck RI, de Azevedo LR, Mazur RF, Moysés SJ, Moysés ST, Faucz FR, Trevilatto PC
  J Appl Oral Sci. 2010
  PubMed ID: 20485928
   
  
• Fecal lactoferrin, myeloperoxidase and serum C-reactive are effective biomarkers in the assessment of disease activity and severity in patients with idiopathic ulcerative colitis.
  Masoodi I, Kochhar R, Dutta U, Vaishnavi C, Prasad KK, Vaiphei K, Kaur S, Singh K
  J Gastroenterol Hepatol. 2009
  PubMed ID: 20136960
   
  
• Immunolocalization of lactoferrin in cartilage-forming neoplasms.
  Ieni A, Barresi V, Grosso M, Rosa MA, Tuccari G
  J Orthop Sci. 2009
  PubMed ID: 19997820
   
  
• Study of interaction of ceruloplasmin, lactoferrin, and myeloperoxidase by photon correlation spectroscopy.
  Sokolov AV, Prozorovskii VN, Vasilyev VB
  Biochemistry (Mosc). 2009
  PubMed ID: 19916937
   
  
• Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
  Wheeler HE, Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK
  PLoS Genet. 2009
  PubMed ID: 19834535
   
  
• Flagellum-mediated biofilm defense mechanisms of Pseudomonas aeruginosa against host-derived lactoferrin.
  Leid JG, Kerr M, Selgado C, Johnson C, Moreno G, Smith A, Shirtliff ME, O'Toole GA, Cope EK
  Infect Immun. 2009
  PubMed ID: 19651866
   
  
• DNA, oligosaccharides, and mononucleotides stimulate oligomerization of human lactoferrin.
  Nevinskii AG, Soboleva SE, Tuzikov FV, Buneva VN, Nevinsky GA
  J Mol Recognit. 2009
  PubMed ID: 19382280
   
  
• Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN.
  Adams WC, Bond E, Havenga MJ, Holterman L, Goudsmit J, Karlsson Hedestam GB, Koup RA, Loré K
  J Gen Virol. 2009
  PubMed ID: 19282435
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
  Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R
  Pediatr Infect Dis J. 2009
  PubMed ID: 19258923
   
  
• Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease.
  An L, Sato H, Konishi Y, Walker DG, Beach TG, Rogers J, Tooyama I
  Neurosci Lett. 2009
  PubMed ID: 19348738
   
  
• [Relationship of concentration of lactoferrin and lysozyme in saliva and dental caries in primary dentition].
  Hao GF, Lin HC
  Zhonghua Kou Qiang Yi Xue Za Zhi. 2009
  PubMed ID: 19563039
   
  
• Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
  Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
  J Proteome Res. 2009
  PubMed ID: 19159218
   
  
• A novel cell-surface protein CSP82 on bone marrow stem cells and a cytosolic phosphoprotein DP58 (ankyrinRD 34B) are involved in promyeloid progenitor induction.
  Al-Shaibi N, Ghosh SK
  Cell Immunol. 2009
  PubMed ID: 19524877
   
  
• Lactoferrin in chronic pancreatitis.
  Jin CX, Hayakawa T, Kitagawa M, Ishiguro H
  JOP. 2009
  PubMed ID: 19454813
   
  
• Human lactoferrin but not lysozyme neutralizes HSV-1 and inhibits HSV-1 replication and cell-to-cell spread.
  Välimaa H, Tenovuo J, Waris M, Hukkanen V
  Virol J. 2009
  PubMed ID: 19435495
   
  
• [DNA and oligosaccharides stimulate oligomerization of human milk lactoferrin]
  Soboleva SE, Tuzikov FV, Tuzikova NA, Buneva VN, Nevinskiĭ GA
  Mol Biol (Mosk). 2009
  PubMed ID: 19334538
   
  
• Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
  Ieni A, Barresi V, Grosso M, Rosa MA, Tuccari G
  J Bone Miner Metab. 2009
  PubMed ID: 19240970
   
  
• Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin.
  Bournazou I, Pound JD, Duffin R, Bournazos S, Melville LA, Brown SB, Rossi AG, Gregory CD
  J Clin Invest. 2009
  PubMed ID: 19033648
   
  
• Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.
  Starr JM, Shiels PG, Harris SE, Pattie A, Pearce MS, Relton CL, Deary IJ
  Mech Ageing Dev. 2008
  PubMed ID: 18977241
   
  
• Lactoferrin induces cell surface retention of prion protein and inhibits prion accumulation.
  Iwamaru Y, Shimizu Y, Imamura M, Murayama Y, Endo R, Tagawa Y, Ushiki-Kaku Y, Takenouchi T, Kitani H, Mohri S, Yokoyama T, Okada H
  J Neurochem. 2008
  PubMed ID: 18717818
   
  
• Lactotransferrin: a candidate tumor suppressor-Deficient expression in human nasopharyngeal carcinoma and inhibition of NPC cell proliferation by modulating the mitogen-activated protein kinase pathway.
  Zhou Y, Zeng Z, Zhang W, Xiong W, Wu M, Tan Y, Yi W, Xiao L, Li X, Huang C, Cao L, Tang K, Li X, Shen S, Li G
  Int J Cancer. 2008
  PubMed ID: 18697201
   
  
• The N1 domain of human lactoferrin is required for internalization by caco-2 cells and targeting to the nucleus.
  Suzuki YA, Wong H, Ashida KY, Schryvers AB, Lönnerdal B
  Biochemistry. 2008
  PubMed ID: 18785755
   
  
• Association between lactoferrin gene polymorphisms and aggressive periodontitis among Taiwanese patients.
  Wu YM, Juo SH, Ho YP, Ho KY, Yang YH, Tsai CC
  J Periodontal Res. 2008
  PubMed ID: 18973542
   
  
• Talactoferrin stimulates wound healing with modulation of inflammation.
  Engelmayer J, Blezinger P, Varadhachary A
  J Surg Res. 2008
  PubMed ID: 18619616
   
  
• Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry.
  Picariello G, Ferranti P, Mamone G, Roepstorff P, Addeo F
  Proteomics. 2008
  PubMed ID: 18780401
   
  
• Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
  de la Rosa G, Yang D, Tewary P, Varadhachary A, Oppenheim JJ
  J Immunol. 2008
  PubMed ID: 18453607
   
  
• The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
  Jacobsen LC, Sørensen OE, Cowland JB, Borregaard N, Theilgaard-Mönch K
  J Leukoc Biol. 2008
  PubMed ID: 18285402
   
  
• Stimulus-dependent impairment of the neutrophil oxidative burst response in lactoferrin-deficient mice.
  Ward PP, Mendoza-Meneses M, Park PW, Conneely OM
  Am J Pathol. 2008
  PubMed ID: 18321995
   
  
• Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status.
  Moreno-Navarrete JM, Ortega FJ, Bassols J, Castro A, Ricart W, Fernández-Real JM
  Clin Chem. 2008
  PubMed ID: 18156281
   
  
• Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis.
  Keijser S, Jager MJ, Dogterom-Ballering HC, Schoonderwoerd DT, de Keizer RJ, Krose CJ, Houwing-Duistermaat JJ, van der Plas MJ, van Dissel JT, Nibbering PH
  Exp Eye Res. 2008
  PubMed ID: 18022620
   
  
• Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
  Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
  Cell. 2007
  PubMed ID: 18083107
   
  
• A distinct role of neutrophil lactoferrin in RelA/p65 phosphorylation on Ser536 by recruiting TNF receptor-associated factors to IkappaB kinase signaling complex.
  Oh SM, Lee SH, Lee BJ, Pyo CW, Yoo NK, Lee SY, Kim J, Choi SY
  J Immunol. 2007
  PubMed ID: 17947640
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
  Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B
  J Infect Dis. 2007
  PubMed ID: 17703412
   
  
• Structural characterization of the ceruloplasmin: lactoferrin complex in solution.
  Sabatucci A, Vachette P, Vasilyev VB, Beltramini M, Sokolov A, Pulina M, Salvato B, Angelucci CB, Maccarrone M, Cozzani I, Dainese E
  J Mol Biol. 2007
  PubMed ID: 17597152
   
  
• Structure of a complex of human lactoferrin N-lobe with pneumococcal surface protein a provides insight into microbial defense mechanism.
  Senkovich O, Cook WJ, Mirza S, Hollingshead SK, Protasevich II, Briles DE, Chattopadhyay D
  J Mol Biol. 2007
  PubMed ID: 17543335
   
  
• Silencing of Lactotransferrin expression by methylation in prostate cancer progression.
  Shaheduzzaman S, Vishwanath A, Furusato B, Cullen J, Chen Y, Bañez L, Nau M, Ravindranath L, Kim KH, Mohammed A, Chen Y, Ehrich M, Srikantan V, Sesterhenn IA, McLeod D, Vahey M, Petrovics G, Dobi A, Srivastava S
  Cancer Biol Ther. 2007
  PubMed ID: 17568188
   
  
• A calorimetric study of thermal denaturation of recombinant human lactoferrin from rice.
  Conesa C, Sánchez L, Pérez MD, Calvo M
  J Agric Food Chem. 2007
  PubMed ID: 17503830
   
  
• Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion.
  Zarember KA, Sugui JA, Chang YC, Kwon-Chung KJ, Gallin JI
  J Immunol. 2007
  PubMed ID: 17475866
   
  
• Immunoexpression of lactoferrin in human sporadic renal cell carcinomas.
  Giuffrè G, Barresi V, Skliros C, Barresi G, Tuccari G
  Oncol Rep. 2007
  PubMed ID: 17390038
   
  
• High-level expression of human lactoferrin in the milk of goats by using replication-defective adenoviral vectors.
  Han ZS, Li QW, Zhang ZY, Xiao B, Gao DW, Wu SY, Li J, Zhao HW, Jiang ZL, Hu JH
  Protein Expr Purif. 2007
  PubMed ID: 17208010
   
  
• Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation.
  Buccigrossi V, de Marco G, Bruzzese E, Ombrato L, Bracale I, Polito G, Guarino A
  Pediatr Res. 2007
  PubMed ID: 17515863
   
  
• A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to Mexico.
  Mohamed JA, DuPont HL, Jiang ZD, Belkind-Gerson J, Figueroa JF, Armitige LY, Tsai A, Nair P, Martinez-Sandoval FJ, Guo DC, Hayes P, Okhuysen PC
  Clin Infect Dis. 2007
  PubMed ID: 17342646
   
  
• Usefulness of fecal lactoferrin and hemoglobin in diagnosis of colorectal diseases.
  Hirata I, Hoshimoto M, Saito O, Kayazawa M, Nishikawa T, Murano M, Toshina K, Wang FY, Matsuse R
  World J Gastroenterol. 2007
  PubMed ID: 17461450
   
  
• Cleaved inflammatory lactoferrin peptides in parotid saliva of periodontitis patients.
  Komine K, Kuroishi T, Ozawa A, Komine Y, Minami T, Shimauchi H, Sugawara S
  Mol Immunol. 2007
  PubMed ID: 17030385
   
  
• Decreased lactoferrin levels in peritoneal fluid of women with minimal endometriosis.
  Polak G, Wertel I, Tarkowski R, Morawska D, Kotarski J
  Eur J Obstet Gynecol Reprod Biol. 2007
  PubMed ID: 16644090
   
  
• A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
  Harris SE, Fox H, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ
  BMC Genet. 2007
  PubMed ID: 17601350
   
  
• Large-scale mapping of human protein-protein interactions by mass spectrometry.
  Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
  Mol Syst Biol. 2007
  PubMed ID: 17353931
   
  
• Effects of iron-unsaturated human lactoferrin on hydrogen peroxide-induced oxidative damage in intestinal epithelial cells.
  Shoji H, Oguchi S, Shinohara K, Shimizu T, Yamashiro Y
  Pediatr Res. 2007
  PubMed ID: 17211147
   
  
• Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells.
  Johansson C, Jonsson M, Marttila M, Persson D, Fan XL, Skog J, Frängsmyr L, Wadell G, Arnberg N
  J Virol. 2007
  PubMed ID: 17079302
   
  
• Transgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection.
  Hyvönen P, Suojala L, Orro T, Haaranen J, Simola O, Røntved C, Pyörälä S
  Infect Immun. 2006
  PubMed ID: 16954396
   
  
• Differential modulation of human lactoferrin activity against both R5 and X4-HIV-1 adsorption on epithelial cells and dendritic cells by natural antibodies.
  Saidi H, Eslahpazir J, Eslaphazir J, Carbonneil C, Carthagena L, Requena M, Nassreddine N, Belec L
  J Immunol. 2006
  PubMed ID: 17015741
   
  
• Modulation of cell adhesion and motility in the immune system by Myo1f.
  Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA
  Science. 2006
  PubMed ID: 17023661
   
  
• Comparison of human immunodeficiency virus type 1-specific inhibitory activities in saliva and other human mucosal fluids.
  Kazmi SH, Naglik JR, Sweet SP, Evans RW, O'Shea S, Banatvala JE, Challacombe SJ
  Clin Vaccine Immunol. 2006
  PubMed ID: 16928883
   
  
• Antioxidant and antibacterial genes are upregulated in early involution of the mouse mammary gland: sharp increase of ceruloplasmin and lactoferrin in accumulating breast milk.
  Nakamura M, Tomita A, Nakatani H, Matsuda T, Nadano D
  DNA Cell Biol. 2006
  PubMed ID: 16989572
   
  
• Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2.
  Wang H, He S
  Cell Biol Int. 2006
  PubMed ID: 16820307
   
  
• Interaction of human lactoferrin with cell adhesion molecules through RGD motif elucidated by lactoferrin-binding epitopes.
  Sakamoto K, Ito Y, Mori T, Sugimura K
  J Biol Chem. 2006
  PubMed ID: 16787913
   
  
• Human lactoferrin upregulates expression of KDR/Flk-1 and stimulates VEGF-A-mediated endothelial cell proliferation and migration.
  Kim CW, Son KN, Choi SY, Kim J
  FEBS Lett. 2006
  PubMed ID: 16842782
   
  
• Intelectin: a novel lipid raft-associated protein in the enterocyte brush border.
  Wrackmeyer U, Hansen GH, Seya T, Danielsen EM
  Biochemistry. 2006
  PubMed ID: 16866365
   
  
• Release of surface-expressed lactoferrin from polymorphonuclear neutrophils after contact with CD4+ T cells and its modulation on Th1/Th2 cytokine production.
  Li KJ, Lu MC, Hsieh SC, Wu CH, Yu HS, Tsai CY, Yu CL
  J Leukoc Biol. 2006
  PubMed ID: 16769765
   
  
• Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice.
  Kholodnyuk ID, Kozireva S, Kost-Alimova M, Kashuba V, Klein G, Imreh S
  Int J Cancer. 2006
  PubMed ID: 16432833
   
  
• A novel apoptosis cascade mediated by lysosomal lactoferrin and its participation in hepatocyte apoptosis induced by D-galactosamine.
  Katunuma N, Le QT, Murata E, Matsui A, Majima E, Ishimaru N, Hayashi Y, Ohashi A
  FEBS Lett. 2006
  PubMed ID: 16765951
   
  
• Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway.
  Grey A, Zhu Q, Watson M, Callon K, Cornish J
  Mol Cell Endocrinol. 2006
  PubMed ID: 16650524
   
  
• Single nucleotide polymorphisms (SNPs) in human lactoferrin gene.
  Teng CT, Gladwell W
  Biochem Cell Biol. 2006
  PubMed ID: 16936811
   
  
• Human lactoferrin controls the level of retinoblastoma protein and its activity.
  Son HJ, Lee SH, Choi SY
  Biochem Cell Biol. 2006
  PubMed ID: 16936805
   
  
• Lactoferrin and bone; structure-activity relationships.
  Cornish J, Palmano K, Callon KE, Watson M, Lin JM, Valenti P, Naot D, Grey AB, Reid IR
  Biochem Cell Biol. 2006
  PubMed ID: 16936800
   
  
• The DNA sequence, annotation and analysis of human chromosome 3.
  Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA
  Nature. 2006
  PubMed ID: 16641997
   
  
• BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
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  PLoS Biol. 2006
  PubMed ID: 16602821
   
  
• Genetic and epigenetic inactivation of LTF gene at 3p21.3 in lung cancers.
  Iijima H, Tomizawa Y, Iwasaki Y, Sato K, Sunaga N, Dobashi K, Saito R, Nakajima T, Minna JD, Mori M
  Int J Cancer. 2006
  PubMed ID: 16152584
   
  
• Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.
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  Oncol Res. 2006
  PubMed ID: 17476971
   
  
• Multifunctional roles of lactoferrin: a critical overview.
  Ward PP, Paz E, Conneely OM
  Cell Mol Life Sci. 2005
  PubMed ID: 16261256
   
  
• Lactoferrin: an important host defence against microbial and viral attack.
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  Cell Mol Life Sci. 2005
  PubMed ID: 16261253
   
  
• Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation.
  Tranguch S, Cheung-Flynn J, Daikoku T, Prapapanich V, Cox MB, Xie H, Wang H, Das SK, Smith DF, Dey SK
  Proc Natl Acad Sci U S A. 2005
  PubMed ID: 16176985
   
  
• A non-conservative, coding single-nucleotide polymorphism in the N-terminal region of lactoferrin is associated with aggressive periodontitis in an African-American, but not a Caucasian population.
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  Genes Immun. 2005
  PubMed ID: 16208406
   
  
• Antisense transcription in the mammalian transcriptome.
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  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
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  Science. 2005
  PubMed ID: 16141072
   
  
• Transcriptome analysis in blastocyst hatching by cDNA microarray.
  Chen HW, Chen JJ, Yu SL, Li HN, Yang PC, Su CM, Au HK, Chang CW, Chien LW, Chen CS, Tzeng CR
  Hum Reprod. 2005
  PubMed ID: 15919778
   
  
• High level expression of functionally active human lactoferrin in silkworm larvae.
  Liu T, Zhang YZ, Wu XF
  J Biotechnol. 2005
  PubMed ID: 15993972
   
  
• Salivary lactoferrin is recognized by the human herpesvirus-8.
  Grange PA, Marcelin AG, Calvez V, Chauvel C, Escande JP, Dupin N
  J Invest Dermatol. 2005
  PubMed ID: 15955101
   
  
• The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts.
  Ozyildirim AM, Wistow GJ, Gao J, Wang J, Dickinson DP, Frierson HF, Laurie GW
  Invest Ophthalmol Vis Sci. 2005
  PubMed ID: 15851553
   
  
• The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling.
  Kim BM, Buchner G, Miletich I, Sharpe PT, Shivdasani RA
  Dev Cell. 2005
  PubMed ID: 15809042
   
  
• Antibiotic tolerance induced by lactoferrin in clinical Pseudomonas aeruginosa isolates from cystic fibrosis patients.
  Andrés MT, Viejo-Diaz M, Pérez F, Fierro JF
  Antimicrob Agents Chemother. 2005
  PubMed ID: 15793153
   
  
• Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer.
  Benaïssa M, Peyrat JP, Hornez L, Mariller C, Mazurier J, Pierce A
  Int J Cancer. 2005
  PubMed ID: 15543612
   
  
• Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction.
  Groot F, Geijtenbeek TB, Sanders RW, Baldwin CE, Sanchez-Hernandez M, Floris R, van Kooyk Y, de Jong EC, Berkhout B
  J Virol. 2005
  PubMed ID: 15709021
   
  
• Gene and alternative splicing annotation with AIR.
  Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
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  PubMed ID: 15632090
   
  
• Protein partners of C/EBPepsilon.
  Chih DY, Park DJ, Gross M, Idos G, Vuong PT, Hirama T, Chumakov AM, Said J, Koeffler HP
  Exp Hematol. 2004
  PubMed ID: 15588942
   
  
• PRAM-1 is required for optimal integrin-dependent neutrophil function.
  Clemens RA, Newbrough SA, Chung EY, Gheith S, Singer AL, Koretzky GA, Peterson EJ
  Mol Cell Biol. 2004
  PubMed ID: 15572693
   
  
• Neutrophil lactoferrin upregulates the human p53 gene through induction of NF-kappaB activation cascade.
  Oh SM, Pyo CW, Kim Y, Choi SY
  Oncogene. 2004
  PubMed ID: 15378004
   
  
• Estrogen response element and the promoter context of the human and mouse lactoferrin genes influence estrogen receptor alpha-mediated transactivation activity in mammary gland cells.
  Stokes K, Alston-Mills B, Teng C
  J Mol Endocrinol. 2004
  PubMed ID: 15525592
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Effects of human lactoferrin on the cytoplasmic membrane of Candida albicans cells related with its candidacidal activity.
  Viejo-Díaz M, Andrés MT, Fierro JF
  FEMS Immunol Med Microbiol. 2004
  PubMed ID: 15364102
   
  
• Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
  Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S
  Genome Res. 2004
  PubMed ID: 15342556
   
  
• Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy.
  Varadhachary A, Wolf JS, Petrak K, O'Malley BW, Spadaro M, Curcio C, Forni G, Pericle F
  Int J Cancer. 2004
  PubMed ID: 15221967
   
  
• Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo.
  Cornish J, Callon KE, Naot D, Palmano KP, Banovic T, Bava U, Watson M, Lin JM, Tong PC, Chen Q, Chan VA, Reid HE, Fazzalari N, Baker HM, Baker EN, Haggarty NW, Grey AB, Reid IR
  Endocrinology. 2004
  PubMed ID: 15166119
   
  
• Expression of delta-lactoferrin induces cell cycle arrest.
  Breton M, Mariller C, Benaïssa M, Caillaux K, Browaeys E, Masson M, Vilain JP, Mazurier J, Pierce A
  Biometals. 2004
  PubMed ID: 15222485
   
  
• Methylation and expression of the lactoferrin gene in human tissues and cancer cells.
  Teng C, Gladwell W, Raphiou I, Liu E
  Biometals. 2004
  PubMed ID: 15222484
   
  
• Baculovirus expression of mouse lactoferrin receptor and tissue distribution in the mouse.
  Suzuki YA, Lönnerdal B
  Biometals. 2004
  PubMed ID: 15222482
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
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• Steady-state plasma lactoferrin levels in relation to infections and complications of sickle cell disease.
  Okpala I, Ugochukwu CC, Tawil A, Greaves R
  Hematol J. 2004
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• Complete sequencing and characterization of 21,243 full-length human cDNAs.
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  Nat Genet. 2004
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• Fine mapping of the circling (cir) gene on the distal portion of mouse chromosome 9.
  Cho KI, Lee JW, Kim KS, Lee EJ, Suh JG, Lee HJ, Kim HT, Hong SH, Chung WH, Chang KT, Hyun BH, Oh YS, Ryoo ZY
  Comp Med. 2003
  PubMed ID: 14727813
   
  
• One of two human lactoferrin variants exhibits increased antibacterial and transcriptional activation activities and is associated with localized juvenile periodontitis.
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  Infect Immun. 2003
  PubMed ID: 14573629
   
  
• New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors.
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  Biochem Biophys Res Commun. 2003
  PubMed ID: 12788072
   
  
• MG2 and lactoferrin form a heterotypic complex in salivary secretions.
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  J Dent Res. 2003
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• [Lactoferrin and its role in the pathogenesis of tick-borne encephalitis]
  Merzeniuk ZA, Lykova OF, Konysheva TV
  Klin Lab Diagn. 2003
  PubMed ID: 12774664
   
  
• Arginine 25 and Arginine 28 of lactoferrin are critical for effective heparin neutralization in blood.
  Wu HM, Church FC
  Arch Biochem Biophys. 2003
  PubMed ID: 12646274
   
  
• Identification of a lactoferrin-derived peptide possessing binding activity to hepatitis C virus E2 envelope protein.
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  J Biol Chem. 2003
  PubMed ID: 12522210
   
  
• Lactoferrin-protector against oxidative stress and regulator of glycolysis in human erythrocytes.
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  PubMed ID: 12710738
   
  
• An intronic alternative promoter of the human lactoferrin gene is activated by Ets.
  Liu D, Wang X, Zhang Z, Teng CT
  Biochem Biophys Res Commun. 2003
  PubMed ID: 12565886
   
  
• Potassium efflux induced by a new lactoferrin-derived peptide mimicking the effect of native human lactoferrin on the bacterial cytoplasmic membrane.
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  Biochemistry (Mosc). 2003
  PubMed ID: 12693969
   
  
• Effect of exercise on immunologic factors in breast milk.
  Lovelady CA, Hunter CP, Geigerman C
  Pediatrics. 2003
  PubMed ID: 12563088
   
  
• Human milk lactoferrin is a serine protease that cleaves Haemophilus surface proteins at arginine-rich sites.
  Hendrixson DR, Qiu J, Shewry SC, Fink DL, Petty S, Baker EN, Plaut AG, St Geme JW
  Mol Microbiol. 2003
  PubMed ID: 12535064
   
  
• In vitro characterization of lactoferrin aggregation and amyloid formation.
  Nilsson MR, Dobson CM
  Biochemistry. 2003
  PubMed ID: 12525164
   
  
• Iron status in mice carrying a targeted disruption of lactoferrin.
  Ward PP, Mendoza-Meneses M, Cunningham GA, Conneely OM
  Mol Cell Biol. 2003
  PubMed ID: 12482971
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• "Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin.
  Peterson NA, Arcus VL, Anderson BF, Tweedie JW, Jameson GB, Baker EN
  Biochemistry. 2002
  PubMed ID: 12450380
   
  
• Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis.
  Gomez HF, Ochoa TJ, Herrera-Insua I, Carlin LG, Cleary TG
  Infect Immun. 2002
  PubMed ID: 12438385
   
  
• Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.
  Kiss H, Darai E, Kiss C, Kost-Alimova M, Klein G, Dumanski JP, Imreh S
  Mamm Genome. 2002
  PubMed ID: 12461651
   
  
• Differential expression and estrogen response of lactoferrin gene in the female reproductive tract of mouse, rat, and hamster.
  Teng CT, Beard C, Gladwell W
  Biol Reprod. 2002
  PubMed ID: 12390874
   
  
• Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice.
  Kruzel ML, Harari Y, Mailman D, Actor JK, Zimecki M
  Clin Exp Immunol. 2002
  PubMed ID: 12296849
   
  
• Characterization of monoclonal antibodies against human lactoferrin.
  van Berkel PH, van Veen HA, Geerts ME, Nuijens JH
  J Immunol Methods. 2002
  PubMed ID: 12165435
   
  
• Multivalent metal-induced iron acquisition from transferrin and lactoferrin by myeloid cells.
  Olakanmi O, Rasmussen GT, Lewis TS, Stokes JB, Kemp JD, Britigan BE
  J Immunol. 2002
  PubMed ID: 12165535
   
  
• Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6.
  Mitchem KL, Hibbard E, Beyer LA, Bosom K, Dootz GA, Dolan DF, Johnson KR, Raphael Y, Kohrman DC
  Hum Mol Genet. 2002
  PubMed ID: 12140191
   
  
• Immobilized lactoferrin is a stimulus for eosinophil activation.
  Thomas LL, Xu W, Ardon TT
  J Immunol. 2002
  PubMed ID: 12097406
   
  
• A novel localized amyloidosis associated with lactoferrin in the cornea.
  Ando Y, Nakamura M, Kai H, Katsuragi S, Terazaki H, Nozawa T, Okuda T, Misumi S, Matsunaga N, Hata K, Tajiri T, Shoji S, Yamashita T, Haraoka K, Obayashi K, Matsumoto K, Ando M, Uchino M
  Lab Invest. 2002
  PubMed ID: 12065686
   
  
• A component of innate immunity prevents bacterial biofilm development.
  Singh PK, Parsek MR, Greenberg EP, Welsh MJ
  Nature. 2002
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• Enhanced Th1 response to Staphylococcus aureus infection in human lactoferrin-transgenic mice.
  Guillén C, McInnes IB, Vaughan DM, Kommajosyula S, Van Berkel PH, Leung BP, Aguila A, Brock JH
  J Immunol. 2002
  PubMed ID: 11937551
   
  
• Killing activity of neutrophils is mediated through activation of proteases by K+ flux.
  Reeves EP, Lu H, Jacobs HL, Messina CG, Bolsover S, Gabella G, Potma EO, Warley A, Roes J, Segal AW
  Nature. 2002
  PubMed ID: 11907569
   
  
• Lactoferrin: influences on Langerhans cells, epidermal cytokines, and cutaneous inflammation.
  Kimber I, Cumberbatch M, Dearman RJ, Headon DR, Bhushan M, Griffiths CE
  Biochem Cell Biol. 2002
  PubMed ID: 11911118
   
  
• Studies of the ceruloplasmin-lactoferrin complex.
  Pulina MO, Zakharova ET, Sokolov AV, Shavlovski MM, Bass MG, Solovyov KV, Kokryakov VN, Vasilyev VB
  Biochem Cell Biol. 2002
  PubMed ID: 11908641
   
  
• Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element.
  Zhang Z, Teng CT
  Biochem Cell Biol. 2002
  PubMed ID: 11908639
   
  
• Detection of exon polymorphisms in the human lactoferrin gene.
  Liu LH, Gladwell W, Teng CT
  Biochem Cell Biol. 2002
  PubMed ID: 11908638
   
  
• Lactoferrin gene expression is estrogen responsive in human and rhesus monkey endometrium.
  Teng CT, Gladwell W, Beard C, Walmer D, Teng CS, Brenner R
  Mol Hum Reprod. 2002
  PubMed ID: 11756570
   
  
• The binding of lactoferrin to glycosaminoglycans on enterocyte-like HT29-18-C1 cells is mediated through basic residues located in the N-terminus.
  El Yazidi-Belkoura I, Legrand D, Nuijens J, Slomianny MC, van Berkel P, Spik G
  Biochim Biophys Acta. 2001
  PubMed ID: 11786226
   
  
• Is tumor necrosis factor genotype (TNFA2/TNFA2)a genetic prognostic factor of an unfavorable outcome in IgA nephropathy?
  Lee EY, Yang DH, Hwang KY, Hong SY
  J Korean Med Sci. 2001
  PubMed ID: 11748357
   
  
• Identification of an import signal for, and the nuclear localization of, human lactoferrin.
  Penco S, Scarfi S, Giovine M, Damonte G, Millo E, Villaggio B, Passalacqua M, Pozzolini M, Garrè C, Benatti U
  Biotechnol Appl Biochem. 2001
  PubMed ID: 11730482
   
  
• Human lactoferrin: a novel therapeutic with broad spectrum potential.
  Weinberg ED
  J Pharm Pharmacol. 2001
  PubMed ID: 11697537
   
  
• Bacteriostatic activity of human lactoferrin against Staphylococcus aureus is a function of its iron-binding properties and is not influenced by antibiotic resistance.
  Aguila A, Herrera AG, Morrison D, Cosgrove B, Perojo A, Montesinos I, Pérez J, Sierra G, Gemmell CG, Brock JH
  FEMS Immunol Med Microbiol. 2001
  PubMed ID: 11549422
   
  
• [cDNA cloning and sequence analysis of human lactoferrin]
  Cheng H, Chen XZ, Huan LD
  Sheng Wu Gong Cheng Xue Bao. 2001
  PubMed ID: 11702692
   
  
• Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall.
  Tsuji S, Uehori J, Matsumoto M, Suzuki Y, Matsuhisa A, Toyoshima K, Seya T
  J Biol Chem. 2001
  PubMed ID: 11313366
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
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• Length of uninterrupted repeats determines instability at the unstable mouse expanded simple tandem repeat family MMS10 derived from independent SINE B1 elements.
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  Mamm Genome. 2001
  PubMed ID: 11210178
   
  
• Human lactoferrin in the milk of transgenic mice increases intestinal growth in ten-day-old suckling neonates.
  Zhang P, Sawicki V, Lewis A, Hanson L, Nuijens JH, Neville MC
  Adv Exp Med Biol. 2001
  PubMed ID: 11787671
   
  
• Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex.
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  Infect Immun. 2000
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• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
  Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
  Genome Res. 2000
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• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
  Genome Res. 2000
  PubMed ID: 11042159
   
  
• Surface expression of lactoferrin by resting neutrophils.
  Deriy LV, Chor J, Thomas LL
  Biochem Biophys Res Commun. 2000
  PubMed ID: 10944471
   
  
• Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
  Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
  Proc Natl Acad Sci U S A. 2000
  PubMed ID: 10922068
   
  
• Interaction of lactoferrin with ceruloplasmin.
  Zakharova ET, Shavlovski MM, Bass MG, Gridasova AA, Pulina MO, De Filippis V, Beltramini M, Di Muro P, Salvato B, Fontana A, Vasilyev VB, Gaitskhoki VS
  Arch Biochem Biophys. 2000
  PubMed ID: 10666301
   
  
• Interaction of tear lipocalin with lysozyme and lactoferrin.
  Gasymov OK, Abduragimov AR, Yusifov TN, Glasgow BJ
  Biochem Biophys Res Commun. 1999
  PubMed ID: 10558865
   
  
• Developmental expression of NADPH phagocytic oxidase components in mouse embryos.
  Baehner RL, Millar-Groff S, Bringas P
  Pediatr Res. 1999
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• Decreased tear lactoferrin concentration in patients with chronic hepatitis C.
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  Br J Ophthalmol. 1999
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• Restricted spatiotemporal expression of lactoferrin during murine embryonic development.
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  Endocrinology. 1999
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• Structure of recombinant human lactoferrin expressed in Aspergillus awamori.
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  Acta Crystallogr D Biol Crystallogr. 1999
  PubMed ID: 10089347
   
  
• High-efficiency full-length cDNA cloning.
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  Methods Enzymol. 1999
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• Familial subepithelial corneal amyloidosis (gelatinous drop-like corneal dystrophy): exclusion of linkage to lactoferrin gene.
  Klintworth GK, Sommer JR, Obrian G, Han L, Ahmed MN, Qumsiyeh MB, Lin PY, Basti S, Reddy MK, Kanai A, Hotta Y, Sugar J, Kumaramanickavel G, Munier F, Schorderet DF, El Matri L, Iwata F, Kaiser-Kupfer M, Nagata M, Nakayasu K, Hejtmancik JF, Teng CT
  Mol Vis. 1998
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• Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change.
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  Acta Crystallogr D Biol Crystallogr. 1998
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• Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae.
  Qiu J, Hendrixson DR, Baker EN, Murphy TF, St Geme JW, Plaut AG
  Proc Natl Acad Sci U S A. 1998
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• Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.
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• Lactoferrin. Antiviral activity of lactoferrin.
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• N-terminal stretch Arg2, Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA.
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• Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines.
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  Proc Natl Acad Sci U S A. 1997
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• Mutagenesis of the histidine ligand in human lactoferrin: iron binding properties and crystal structure of the histidine-253-->methionine mutant.
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• Heterogeneity in utilization of N-glycosylation sites Asn624 and Asn138 in human lactoferrin: a study with glycosylation-site mutants.
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• Characterization of the 84-kDa protein with ABH activity in human seminal plasma.
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• The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.
  Marquis ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin GY, Abel KJ, Weber BL, Chodosh LA
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• Structure of human diferric lactoferrin refined at 2.2 A resolution.
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• Amphiregulin is an implantation-specific and progesterone-regulated gene in the mouse uterus.
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• Lactoferrin down-modulates the activity of the granulocyte macrophage colony-stimulating factor promoter in interleukin-1 beta-stimulated cells.
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• Characterization of the goat lactoferrin cDNA: assignment of the relevant locus to bovine U12 synteny group.
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• COUP-TF acts as a competitive repressor for estrogen receptor-mediated activation of the mouse lactoferrin gene.
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• Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.
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• Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse.
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  Mol Endocrinol. 1992
  PubMed ID: 1480183
   
  
• Molecular interactions between human lactotransferrin and the phytohemagglutinin-activated human lymphocyte lactotransferrin receptor lie in two loop-containing regions of the N-terminal domain I of human lactotransferrin.
  Legrand D, Mazurier J, Elass A, Rochard E, Vergoten G, Maes P, Montreuil J, Spik G
  Biochemistry. 1992
  PubMed ID: 1327110
   
  
• Interaction of calmodulin with lactoferrin.
  de Lillo A, Tejerina JM, Fierro JF
  FEBS Lett. 1992
  PubMed ID: 1544444
   
  
• Structure of the murine lactotransferrin gene is similar to the structure of other transferrin-encoding genes and shares a putative regulatory region with the murine myeloperoxidase gene.
  Shirsat NV, Bittenbender S, Kreider BL, Rovera G
  Gene. 1992
  PubMed ID: 1311279
   
  
• Uptake of lactoferrin by mononuclear phagocytes inhibits their ability to form hydroxyl radical and protects them from membrane autoperoxidation.
  Britigan BE, Serody JS, Hayek MB, Charniga LM, Cohen MS
  J Immunol. 1991
  PubMed ID: 1661314
   
  
• Characterization of estrogen-responsive mouse lactoferrin promoter.
  Liu YH, Teng CT
  J Biol Chem. 1991
  PubMed ID: 1939212
   
  
• Expression of cloned human lactoferrin in baby-hamster kidney cells.
  Stowell KM, Rado TA, Funk WD, Tweedie JW
  Biochem J. 1991
  PubMed ID: 2049066
   
  
• Regulation of human bone marrow lactoferrin and myeloperoxidase gene expression by tumor necrosis factor-alpha.
  Srivastava CH, Rado TA, Bauerle D, Broxmeyer HE
  J Immunol. 1991
  PubMed ID: 1703177
   
  
• Complete nucleotide sequence of human mammary gland lactoferrin.
  Rey MW, Woloshuk SL, deBoer HA, Pieper FR
  Nucleic Acids Res. 1990
  PubMed ID: 2402455
   
  
• Nucleotide sequence of human lactoferrin cDNA.
  Powell MJ, Ogden JE
  Nucleic Acids Res. 1990
  PubMed ID: 2374734
   
  
• Isolation and characterization of opioid antagonist peptides derived from human lactoferrin.
  Tani F, Iio K, Chiba H, Yoshikawa M
  Agric Biol Chem. 1990
  PubMed ID: 1369293
   
  
• Identification of a series of differentiation-associated gene sequences from GM-CSF stimulated bone marrow.
  Moscinski LC, Prystowsky MB
  Oncogene. 1990
  PubMed ID: 2181376
   
  
• Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution.
  Anderson BF, Baker HM, Norris GE, Rice DW, Baker EN
  J Mol Biol. 1989
  PubMed ID: 2585506
   
  
• Chromosomal localization of human lactotransferrin gene (LTF) by in situ hybridization.
  McCombs JL, Teng CT, Pentecost BT, Magnuson VL, Moore CM, McGill JR
  Cytogenet Cell Genet. 1988
  PubMed ID: 3356163
   
  
• Assignment of the lactotransferrin gene to human chromosome 3 and to mouse chromosome 9.
  Teng CT, Pentecost BT, Marshall A, Solomon A, Bowman BH, Lalley PA, Naylor SL
  Somat Cell Mol Genet. 1987
  PubMed ID: 3478818
   
  
• Isolation of lactoferrin cDNA from a human myeloid library and expression of mRNA during normal and leukemic myelopoiesis.
  Rado TA, Wei XP, Benz EJ
  Blood. 1987
  PubMed ID: 3477300
   
  
• Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions.
  Pentecost BT, Teng CT
  J Biol Chem. 1987
  PubMed ID: 3611056
   
  
• Class II genes of the human major histocompatibility complex. The DO beta gene is a divergent member of the class II beta gene family.
  Servenius B, Rask L, Peterson PA
  J Biol Chem. 1987
  PubMed ID: 3036827
   
  
• Immunocytochemical localization of lactoferrin in human neutrophils. An ultrastructural and morphometrical study.
  Miyauchi J, Watanabe Y
  Cell Tissue Res. 1987
  PubMed ID: 3028636
   
  
• The interaction between human pancreatic carboxylester hydrolase (bile-salt-stimulated lipase of human milk) and lactoferrin.
  Erlanson-Albertsson C, Sternby B, Johannesson U
  Biochim Biophys Acta. 1985
  PubMed ID: 3995055
   
  
• Human lactotransferrin: amino acid sequence and structural comparisons with other transferrins.
  Metz-Boutigue MH, Jollès J, Mazurier J, Schoentgen F, Legrand D, Spik G, Montreuil J, Jollès P
  Eur J Biochem. 1984
  PubMed ID: 6510420
   
  
• An 88 amino acid long C-terminal sequence of human lactotransferrin.
  Metz-Boutigue MH, Jollès J, Mazurier J, Spik G, Montreuil J, Jollès P
  FEBS Lett. 1982
  PubMed ID: 7049727
   
  
• The present state of the human lactotransferrin sequence. Study and alignment of the cyanogen bromide fragments and characterization of N- and C-terminal domains.
  Metz-Boutigue MH, Mazurier J, Jollès J, Spik G, Montreuil J, Jollès P
  Biochim Biophys Acta. 1981
  PubMed ID: 6794640
   
  

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