LMNB1

Summary Top Help

Gene Description:

lamin B1

Synonyms:

ADLD, Lmnb1, LMNB, LMN2, LMNB1, LMN

Orthologs:

Human LMNB1 (protein-coding), Mouse Lmnb1 (protein-coding), Rat Lmnb1 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Rat: 1

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm35	Rat	chr18:4320091..76880933	72.56	466

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr5:126112315..126172712 (60.40 kb) View in Genome Browser

(Mouse) NCBIM37 - chr18:56867467..56913079 (45.61 kb) View in Genome Browser

(Rat) RGSC3.4 - chr18:52470605..52508022 (37.42 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for LMNB1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for LMNB1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: 4

Reactome: 4

NCI-Nature Pathway Interaction Database: 1

Gene Ontology: 11

Publications from PubMed Top Help

Type 1 Diabetes Publications: 1

Publications: 152

Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.
Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y
Science. 2011
PubMed ID: 22116031
The role of nuclear lamin B1 in cell proliferation and senescence.
Shimi T, Butin-Israeli V, Adam SA, Hamanaka RB, Goldman AE, Lucas CA, Shumaker DK, Kosak ST, Chandel NS, Goldman RD
Genes Dev. 2011
PubMed ID: 22155925
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs).
Lopitz-Otsoa F, Rodriguez-Suarez E, Aillet F, Casado-Vela J, Lang V, Matthiesen R, Elortza F, Rodriguez MS
J Proteomics. 2011
PubMed ID: 22178446
An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair.
Yang SH, Chang SY, Yin L, Tu Y, Hu Y, Yoshinaga Y, de Jong PJ, Fong LG, Young SG
Hum Mol Genet. 2011
PubMed ID: 21659336
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect.
Verstraeten VL, Peckham LA, Olive M, Capell BC, Collins FS, Nabel EG, Young SG, Fong LG, Lammerding J
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21383178
Genomic duplications mediate overexpression of lamin B1 in adult-onset autosomal dominant leukodystrophy (ADLD) with autonomic symptoms.
Schuster J, Sundblom J, Thuresson AC, Hassin-Baer S, Klopstock T, Dichgans M, Cohen OS, Raininko R, Melberg A, Dahl N
Neurogenetics. 2011
PubMed ID: 21225301
Dynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination.
Kang J, Goodman B, Zheng Y, Tantin D
PLoS One. 2011
PubMed ID: 21897860
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Identification of differential protein interactors of lamin A and progerin.
Kubben N, Voncken JW, Demmers J, Calis C, van Almen G, Pinto Y, Misteli T
Nucleus. 2010
PubMed ID: 21327095
Speriolin is a novel human and mouse sperm centrosome protein.
Goto M, O'Brien DA, Eddy EM
Hum Reprod. 2010
PubMed ID: 20542897
A molecular mechanism underlying the neural-specific defect in torsinA mutant mice.
Kim CE, Perez A, Perkins G, Ellisman MH, Dauer WT
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20457914
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM
Science. 2010
PubMed ID: 20360068
A family with autosomal dominant leukodystrophy linked to 5q23.2-q23.3 without lamin B1 mutations.
Brussino A, Vaula G, Cagnoli C, Panza E, Seri M, Di Gregorio E, Scappaticci S, Camanini S, Daniele D, Bradac GB, Pinessi L, Cavalieri S, Grosso E, Migone N, Brusco A
Eur J Neurol. 2010
PubMed ID: 19961535
Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency.
Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20145110
Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 "half-minilamin" dimers.
Kapinos LE, Schumacher J, Mücke N, Machaidze G, Burkhard P, Aebi U, Strelkov SV, Herrmann H
J Mol Biol. 2010
PubMed ID: 20004208
Aire's partners in the molecular control of immunological tolerance.
Abramson J, Giraud M, Benoist C, Mathis D
Cell. 2010
PubMed ID: 20085707
Autosomal dominant leukodystrophy caused by lamin B1 duplications a clinical and molecular case study of altered nuclear function and disease.
Padiath QS, Fu YH
Methods Cell Biol. 2010
PubMed ID: 20816241
Circulating Lamin B1 (LMNB1) biomarker detects early stages of liver cancer in patients.
Sun S, Xu MZ, Poon RT, Day PJ, Luk JM
J Proteome Res. 2010
PubMed ID: 19522540
Identification of novel spartin-interactors shows spartin is a multifunctional protein.
Milewska M, McRedmond J, Byrne PC
J Neurochem. 2009
PubMed ID: 19765186
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M
Neuron. 2009
PubMed ID: 19874786
The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment.
Luo L, Gassman KL, Petell LM, Wilson CL, Bewersdorf J, Shopland LS
J Cell Sci. 2009
PubMed ID: 19773359
NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation.
Choo MK, Yeo H, Zayzafoon M
Bone. 2009
PubMed ID: 19463978
Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.
Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH
Dev Biol. 2009
PubMed ID: 19501082
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
Lamin B1 maintains the functional plasticity of nucleoli.
Martin C, Chen S, Maya-Mendoza A, Lovric J, Sims PF, Jackson DA
J Cell Sci. 2009
PubMed ID: 19383719
Nuclear architecture of rod photoreceptor cells adapts to vision in mammalian evolution.
Solovei I, Kreysing M, Lanctôt C, Kösem S, Peichl L, Cremer T, Guck J, Joffe B
Cell. 2009
PubMed ID: 19379699
Mutations in the lamin B1 gene are not present in multiple sclerosis.
Brussino A, D'Alfonso S, Cagnoli C, Di Gregorio E, Barberis M, Padovan S, Vaula G, Pinessi L, Squadrone S, Abete MC, Collimedaglia L, Guerini FR, Migone N, Brusco A
Eur J Neurol. 2009
PubMed ID: 19348623
miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination.
Lin ST, Fu YH
Dis Model Mech. 2009
PubMed ID: 19259393
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix.
Ma L, Tsai MY, Wang S, Lu B, Chen R, Iii JR, Zhu X, Zheng Y
Nat Cell Biol. 2009
PubMed ID: 19198602
Involvement of nuclear PLCbeta1 in lamin B1 phosphorylation and G2/M cell cycle progression.
Fiume R, Ramazzotti G, Teti G, Chiarini F, Faenza I, Mazzotti G, Billi AM, Cocco L
FASEB J. 2009
PubMed ID: 19028838
A novel family with Lamin B1 duplication associated with adult-onset leucoencephalopathy.
Brussino A, Vaula G, Cagnoli C, Mauro A, Pradotto L, Daniele D, Di Gregorio E, Barberis M, Arduino C, Squadrone S, Abete MC, Migone N, Calabrese O, Brusco A
J Neurol Neurosurg Psychiatry. 2009
PubMed ID: 19151023
Lamin B1 controls oxidative stress responses via Oct-1.
Malhas AN, Lee CF, Vaux DJ
J Cell Biol. 2009
PubMed ID: 19139261
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK
Sci Signal. 2009
PubMed ID: 19690332
In vitro nuclear interactome of the HIV-1 Tat protein.
Gautier VW, Gu L, O'Donoghue N, Pennington S, Sheehy N, Hall WW
Retrovirology. 2009
PubMed ID: 19454010
The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity. 2009
PubMed ID: 19144319
Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype.
Tsika RW, Schramm C, Simmer G, Fitzsimons DP, Moss RL, Ji J
J Biol Chem. 2008
PubMed ID: 18978355
SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages.
Chiu SY, Asai N, Costantini F, Hsu W
PLoS Biol. 2008
PubMed ID: 19090619
The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription.
Shimi T, Pfleghaar K, Kojima S, Pack CG, Solovei I, Goldman AE, Adam SA, Shumaker DK, Kinjo M, Cremer T, Goldman RD
Genes Dev. 2008
PubMed ID: 19141474
Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.
Wang B, Malik R, Nigg EA, Körner R
Anal Chem. 2008
PubMed ID: 19007248
A novel duplication confirms the involvement of 5q23.2 in autosomal dominant leukodystrophy.
Meijer IA, Simoes-Lopes AA, Laurent S, Katz T, St-Onge J, Verlaan DJ, Dupré N, Thibault M, Mathurin J, Bouchard JP, Rouleau GA
Arch Neurol. 2008
PubMed ID: 19001169
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
Mol Cell. 2008
PubMed ID: 18691976
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane.
Mou F, Wills EG, Park R, Baines JD
J Virol. 2008
PubMed ID: 18524819
The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells.
Tang CW, Maya-Mendoza A, Martin C, Zeng K, Chen S, Feret D, Wilson SA, Jackson DA
J Cell Sci. 2008
PubMed ID: 18334554
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
Cantin GT, Yi W, Lu B, Park SK, Xu T, Lee JD, Yates JR
J Proteome Res. 2008
PubMed ID: 18220336
Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.
Imami K, Sugiyama N, Kyono Y, Tomita M, Ishihama Y
Anal Sci. 2008
PubMed ID: 18187866
An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.
Holaska JM, Wilson KL
Biochemistry. 2007
PubMed ID: 17620012
Cell nuclei spin in the absence of lamin b1.
Ji JY, Lee RT, Vergnes L, Fong LG, Stewart CL, Reue K, Young SG, Zhang Q, Shanahan CM, Lammerding J
J Biol Chem. 2007
PubMed ID: 17488709
Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1.
Lee TH, Seng S, Sekine M, Hinton C, Fu Y, Avraham HK, Avraham S
PLoS Med. 2007
PubMed ID: 17550303
Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression.
Malhas A, Lee CF, Sanders R, Saunders NJ, Vaux DJ
J Cell Biol. 2007
PubMed ID: 17312019
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.
Molina H, Horn DM, Tang N, Mathivanan S, Pandey A
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17287340
Large-scale phosphorylation analysis of mouse liver.
Villén J, Beausoleil SA, Gerber SA, Gygi SP
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17242355
A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.
Fossat N, Le Greneur C, Béby F, Vincent S, Godement P, Chatelain G, Lamonerie T
BMC Dev Biol. 2007
PubMed ID: 17980036
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo.
Hosoya-Ohmura S, Mochizuki N, Suzuki M, Ohneda O, Ohneda K, Yamamoto M
J Biol Chem. 2006
PubMed ID: 16945928
A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP
Nat Biotechnol. 2006
PubMed ID: 16964243
Lamin B1 duplications cause autosomal dominant leukodystrophy.
Padiath QS, Saigoh K, Schiffmann R, Asahara H, Yamada T, Koeppen A, Hogan K, Ptácek LJ, Fu YH
Nat Genet. 2006
PubMed ID: 16951681
Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.
Hoffert JD, Pisitkun T, Wang G, Shen RF, Knepper MA
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16641100
Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL
Mol Cell Proteomics. 2006
PubMed ID: 16452087
Phosphoproteome analysis of the human mitotic spindle.
Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16565220
A mitotic lamin B matrix induced by RanGTP required for spindle assembly.
Tsai MY, Wang S, Heidinger JM, Shumaker DK, Adam SA, Goldman RD, Zheng Y
Science. 2006
PubMed ID: 16543417
Cell surface expression of intermediate filament proteins vimentin and lamin B1 in human neutrophil spontaneous apoptosis.
Moisan E, Girard D
J Leukoc Biol. 2006
PubMed ID: 16365157
Nuclear titin interacts with A- and B-type lamins in vitro and in vivo.
Zastrow MS, Flaherty DB, Benian GM, Wilson KL
J Cell Sci. 2006
PubMed ID: 16410549
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope.
Goodchild RE, Kim CE, Dauer WT
Neuron. 2005
PubMed ID: 16364897
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.
Guo D, Han J, Adam BL, Colburn NH, Wang MH, Dong Z, Eizirik DL, She JX, Wang CY
Biochem Biophys Res Commun. 2005
PubMed ID: 16236267
Substrate specificity and activity regulation of protein kinase MELK.
Beullens M, Vancauwenbergh S, Morrice N, Derua R, Ceulemans H, Waelkens E, Bollen M
J Biol Chem. 2005
PubMed ID: 16216881
Large-scale analysis of the human ubiquitin-related proteome.
Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T, Nakayama KI
Proteomics. 2005
PubMed ID: 16196087
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Proteome analysis of a rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space.
Segawa M, Niino K, Mineki R, Kaga N, Murayama K, Sugimoto K, Watanabe Y, Furukawa K, Horigome T
FEBS J. 2005
PubMed ID: 16128803
Global phosphoproteome of HT-29 human colon adenocarcinoma cells.
Kim JE, Tannenbaum SR, White FM
J Proteome Res. 2005
PubMed ID: 16083285
The apparent absence of lamin B1 and emerin in many tissue nuclei is due to epitope masking.
Tunnah D, Sewry CA, Vaux D, Schirmer EC, Morris GE
J Mol Histol. 2005
PubMed ID: 16283426
Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
Nature. 2005
PubMed ID: 15635413
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
The stability of the nuclear lamina polymer changes with the composition of lamin subtypes according to their individual binding strengths.
Schirmer EC, Gerace L
J Biol Chem. 2004
PubMed ID: 15284226
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
The DNA sequence and comparative analysis of human chromosome 5.
Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM
Nature. 2004
PubMed ID: 15372022
Genomic analysis of mouse retinal development.
Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
PLoS Biol. 2004
PubMed ID: 15226823
Lco1 is a novel widely expressed lamin-binding protein in the nuclear interior.
Vlcek S, Foisner R, Wilson KL
Exp Cell Res. 2004
PubMed ID: 15265697
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
Meek SE, Lane WS, Piwnica-Worms H
J Biol Chem. 2004
PubMed ID: 15161933
Lamin B1 is required for mouse development and nuclear integrity.
Vergnes L, Péterfy M, Bergo MO, Young SG, Reue K
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15232008
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility.
Wang Y, Zhang Z, Yan Y, Lemon WJ, LaRegina M, Morrison C, Lubet R, You M
Cancer Res. 2004
PubMed ID: 14996723
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation.
Maske CP, Hollinshead MS, Higbee NC, Bergo MO, Young SG, Vaux DJ
J Cell Biol. 2003
PubMed ID: 14504265
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
Epstein-Barr virus nuclear antigen-1 colocalizes with lamin B1 in the nucleoplasm and along the nuclear rim.
Ito S, Eda H, Ban F, Yanagi K
Arch Virol. 2003
PubMed ID: 12898336
Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos.
Burns KH, Viveiros MM, Ren Y, Wang P, DeMayo FJ, Frail DE, Eppig JJ, Matzuk MM
Science. 2003
PubMed ID: 12714744
Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts.
Lattanzi G, Cenni V, Marmiroli S, Capanni C, Mattioli E, Merlini L, Squarzoni S, Maraldi NM
Biochem Biophys Res Commun. 2003
PubMed ID: 12670476
CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain.
Ceni C, Pochon N, Brun V, Muller-Steffner H, Andrieux A, Grunwald D, Schuber F, De Waard M, Lund F, Villaz M, Moutin MJ
Biochem J. 2003
PubMed ID: 12403647
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Investigation of nuclear architecture with a domain-presenting expression system.
Dreger CK, König AR, Spring H, Lichter P, Herrmann H
J Struct Biol. 2002
PubMed ID: 12490158
Unraveling the organization of the internal nuclear matrix: RNA-dependent anchoring of NuMA to a lamin scaffold.
Barboro P, D'Arrigo C, Diaspro A, Mormino M, Alberti I, Parodi S, Patrone E, Balbi C
Exp Cell Res. 2002
PubMed ID: 12243746
Binding of elements of protein kinase C-alpha regulatory domain to lamin B1.
Tabellini G, Bortul R, Aluigi M, Billi AM, Bareggi R, Grill V, Narducci P, Martelli AM
Cell Signal. 2002
PubMed ID: 12135703
Protein kinase C-beta II Is an apoptotic lamin kinase in polyomavirus-transformed, etoposide-treated pyF111 rat fibroblasts.
Chiarini A, Whitfield JF, Armato U, Dal Pra I
J Biol Chem. 2002
PubMed ID: 11901153
Directed proteomic analysis of the human nucleolus.
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI
Curr Biol. 2002
PubMed ID: 11790298
Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family.
Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S
Cytogenet Genome Res. 2002
PubMed ID: 12438750
Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy.
Ostlund C, Bonne G, Schwartz K, Worman HJ
J Cell Sci. 2001
PubMed ID: 11792809
Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr.
de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC
Science. 2001
PubMed ID: 11691994
Cutting edge: integration of human T lymphocyte cytoskeleton by the cytolinker plectin.
Brown MJ, Hallam JA, Liu Y, Yamada KM, Shaw S
J Immunol. 2001
PubMed ID: 11441066
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis.
Zhang D, Beresford PJ, Greenberg AH, Lieberman J
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11331782
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.
Izumi M, Yanagi K, Mizuno T, Yokoi M, Kawasaki Y, Moon KY, Hurwitz J, Yatagai F, Hanaoka F
Nucleic Acids Res. 2000
PubMed ID: 11095689
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
The inner nuclear membrane.
Worman HJ, Courvalin JC
J Membr Biol. 2000
PubMed ID: 10960149
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Review: nuclear lamins--structural proteins with fundamental functions.
Gruenbaum Y, Wilson KL, Harel A, Goldberg M, Cohen M
J Struct Biol. 2000
PubMed ID: 10806082
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects.
Pan Y, Decker WK, Huq AH, Craigen WJ
Genomics. 1999
PubMed ID: 10444329
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Identification of the lamina-associated-polypeptide-2-binding domain of B-type lamin.
Furukawa K, Kondo T
Eur J Biochem. 1998
PubMed ID: 9490046
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection.
Vodicka MA, Koepp DM, Silver PA, Emerman M
Genes Dev. 1998
PubMed ID: 9436978
An ancient conserved gene expressed in the human inner ear: identification, expression analysis, and chromosomal mapping of human and mouse antiquitin (ATQ1).
Skvorak AB, Robertson NG, Yin Y, Weremowicz S, Her H, Bieber FR, Beisel KW, Lynch ED, Beier DR, Morton CC
Genomics. 1997
PubMed ID: 9417906
Expression of nuclear lamins in human tissues and cancer cell lines and transcription from the promoters of the lamin A/C and B1 genes.
Lin F, Worman HJ
Exp Cell Res. 1997
PubMed ID: 9367621
Mouse TCOF1 is expressed widely, has motifs conserved in nucleolar phosphoproteins, and maps to chromosome 18.
Paznekas WA, Zhang N, Gridley T, Jabs EW
Biochem Biophys Res Commun. 1997
PubMed ID: 9299440
The inner nuclear membrane protein LAP1 forms a native complex with B-type lamins and partitions with spindle-associated mitotic vesicles.
Maison C, Pyrpasopoulou A, Theodoropoulos PA, Georgatos SD
EMBO J. 1997
PubMed ID: 9305626
A- and B-type lamins are differentially expressed in normal human tissues.
Broers JL, Machiels BM, Kuijpers HJ, Smedts F, van den Kieboom R, Raymond Y, Ramaekers FC
Histochem Cell Biol. 1997
PubMed ID: 9243284
Sequence analysis, identification of evolutionary conserved motifs and expression analysis of murine tcof1 provide further evidence for a potential function for the gene and its human homologue, TCOF1.
Dixon J, Hovanes K, Shiang R, Dixon MJ
Hum Mol Genet. 1997
PubMed ID: 9158147
Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.
Reyes JC, Muchardt C, Yaniv M
J Cell Biol. 1997
PubMed ID: 9128241
Lamin proteolysis facilitates nuclear events during apoptosis.
Rao L, Perez D, White E
J Cell Biol. 1996
PubMed ID: 8978814
Genetic localization of Cd63, a member of the transmembrane 4 superfamily, reveals two distinct loci in the mouse genome.
Gwynn B, Eicher EM, Peters LL
Genomics. 1996
PubMed ID: 8661157
Chromosomal assignment of human nuclear envelope protein genes LMNA, LMNB1, and LBR by fluorescence in situ hybridization.
Wydner KL, McNeil JA, Lin F, Worman HJ, Lawrence JB
Genomics. 1996
PubMed ID: 8838815
Chromosomal localisation of genes coding for human and mouse liver cytosolic cysteine dioxygenase.
Jeremiah S, McCann KP, Williams AC, Ramsden DB, Pilz AJ, Fox MF, Povey S
Ann Hum Genet. 1996
PubMed ID: 8835096
Genomic structure of the mouse gene (Lmnb1) encoding nuclear lamin B1.
Maeno H, Sugimoto K, Nakajima N
Genomics. 1995
PubMed ID: 8586436
Protein-protein interactions between human nuclear lamins expressed in yeast.
Ye Q, Worman HJ
Exp Cell Res. 1995
PubMed ID: 7628545
Structural organization of the human gene (LMNB1) encoding nuclear lamin B1.
Lin F, Worman HJ
Genomics. 1995
PubMed ID: 7557986
Identification of nuclear beta II protein kinase C as a mitotic lamin kinase.
Goss VL, Hocevar BA, Thompson LJ, Stratton CA, Burns DJ, Fields AP
J Biol Chem. 1994
PubMed ID: 8034666
Genetic mapping of 40 cDNA clones on the mouse genome by PCR.
Ko MS, Wang X, Horton JH, Hagen MD, Takahashi N, Maezaki Y, Nadeau JH
Mamm Genome. 1994
PubMed ID: 8043949
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.
Rowe LB, Nadeau JH, Turner R, Frankel WN, Letts VA, Eppig JT, Ko MS, Thurston SJ, Birkenmeier EH
Mamm Genome. 1994
PubMed ID: 8075499
cDNA cloning and functional characterization of a meiosis-specific protein (MNS1) with apparent nuclear association.
Furukawa K, Inagaki H, Naruge T, Tabata S, Tomida T, Yamaguchi A, Yoshikuni M, Nagahama Y, Hotta Y
Chromosome Res. 1994
PubMed ID: 8032679
Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation.
Foisner R, Gerace L
Cell. 1993
PubMed ID: 8324822
The differential expression of lamin epitopes during mouse spermatogenesis.
Moss SB, Burnham BL, Bellvé AR
Mol Reprod Dev. 1993
PubMed ID: 7680212
A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18.
Justice MJ, Gilbert DJ, Kinzler KW, Vogelstein B, Buchberg AM, Ceci JD, Matsuda Y, Chapman VM, Patriotis C, Makris A
Genomics. 1992
PubMed ID: 1354644
Protein kinase A- and protein kinase C-regulated interaction of plectin with lamin B and vimentin.
Foisner R, Traub P, Wiche G
Proc Natl Acad Sci U S A. 1991
PubMed ID: 2023931
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments.
Djabali K, Portier MM, Gros F, Blobel G, Georgatos SD
Cell. 1991
PubMed ID: 1986862
Characterization of a second highly conserved B-type lamin present in cells previously thought to contain only a single B-type lamin.
Höger TH, Zatloukal K, Waizenegger I, Krohne G
Chromosoma. 1990
PubMed ID: 2102682
In vitro posttranslational modification of lamin B cloned from a human T-cell line.
Pollard KM, Chan EK, Grant BJ, Sullivan KF, Tan EM, Glass CA
Mol Cell Biol. 1990
PubMed ID: 2325650
Functional characterization of Tat protein from human immunodeficiency virus. Evidence that Tat links viral RNAs to nuclear matrix.
Müller WE, Okamoto T, Reuter P, Ugarkovic D, Schröder HC
J Biol Chem. 1990
PubMed ID: 2406262
Human lamin B contains a farnesylated cysteine residue.
Farnsworth CC, Wolda SL, Gelb MH, Glomset JA
J Biol Chem. 1989
PubMed ID: 2684976
Association of Tat protein and viral mRNA with nuclear matrix from HIV-1-infected H9 cells.
Müller WE, Wenger R, Reuter P, Renneisen K, Schröder HC
Biochim Biophys Acta. 1989
PubMed ID: 2544227
Amino acid sequence and molecular characterization of murine lamin B as deduced from cDNA clones.
Höger TH, Krohne G, Franke WW
Eur J Cell Biol. 1988
PubMed ID: 3243285
Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins.
McKeon FD, Kirschner MW, Caput D
Nature. 1986
PubMed ID: 3453101

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	4001	16906	116685
EnsEMBL Gene(s)	ENSG00000113368	ENSMUSG00000024590	ENSRNOG00000013774
Unigene	Hs.89497	Mm.4105	Rn.11362
Homologene	LMNB1	Lmnb1	Lmnb1
OMIM	150340	N/A	N/A
GeneCards	LMNB1	N/A	N/A
Beta Cell Genomics	DT.102823924 DT.413756 DT.91654824 DT.97781517	DT.496514	N/A
Reactome	P20700	N/A	N/A
Plasma Peptide Atlas	ENSP00000261366	N/A	N/A
WikiGenes	4001	16906	116685

External resources from NIDDK Consortium Interconnectivity Network Top Help

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View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
LMNB1	YWHAQ	BioGRID	empirical	15161933
LMNB1	ZWINT	IntAct, BioGRID	empirical	20360068
LMNB1	SERPINA3	IntAct	empirical	21988832
LMNB1	EMD	BioGRID	empirical	12670476 17620012
LMNB1	SPG20	IntAct, BioGRID	empirical	19765186
LMNB1	SYNE2	Reactome	predicted	8794855
LMNB1	SYNE1	Reactome	predicted	8794855
LMNB1	SUN1	Reactome	predicted	8794855
LMNB1	SUN2	Reactome	predicted	8794855
LMNB1	TOR1AIP1	HPRD	empirical	9305626
LMNB1	GRIN2B	IntAct	empirical	16635246
LMNB1	GZMA	HPRD	empirical	11331782
LMNB1	GZMB	HPRD	empirical	11331782
LMNB1	HLA-B	IntAct	empirical	17353931
LMNB1	AIRE	IntAct, BioGRID	empirical	20085707
LMNB1	SUMO4	HPRD	empirical	16236267
LMNB1	LBR	HPRD	empirical	12490158
LMNB1	LMNA	HPRD, IntAct, BioGRID, Reactome	empirical	11792809 21988832 21327095 8794855
LMNB1	ATF4	IntAct	empirical	21988832
LMNB1	ATM	IntAct, BioGRID	empirical	20360068
LMNB1	MBIP	IntAct	empirical	21988832
LMNB1	PLCB2	MINT, IntAct	empirical	15102471
LMNB1	PLEC	HPRD	empirical	2023931
LMNB1	POU2F1	BioGRID	empirical	21897860
LMNB1	MCM10	BioGRID	empirical	11095689
LMNB1	PRKCA	HPRD	empirical	11901153 12135703
LMNB1	PRKCB	HPRD, BioGRID	empirical	11901153 8034666
LMNB1	PRKCD	HPRD	empirical	11901153
LMNB1	PRPH	HPRD	empirical	1986862
LMNB1	SMARCAD1	BioGRID	empirical	21549307
LMNB1	ABCG8	IntAct	empirical	21988832
LMNB1	SMARCA4	BioGRID	empirical	9128241
LMNB1	SPTAN1	BioGRID	empirical	11441066
LMNB1	TMPO	HPRD, BioGRID	empirical	9490046 8324822
LMNB1	UBC	BioGRID	empirical	16196087 22178446 21139048 21890473 21906983
LMNB1	VIM	BioGRID	empirical	11441066
LMNB1	YWHAZ	MINT	empirical	15161933
LMNB1	NDEL1	BioGRID	empirical	19198602
LMNB1	CASP3	HPRD	empirical	11901153
LMNB1	CASP6	HPRD	empirical	11901153 11331782
LMNB1	BCAR3	IntAct	empirical	17353931
LMNB1	RTCD1	IntAct	empirical	17353931
LMNB1	ATG12	IntAct	empirical	17353931
LMNB1	KIAA0101	BioGRID	empirical	21628590
LMNB1	GIT2	IntAct	empirical	21988832
LMNB1	URB2	HPRD	empirical	15265697
LMNB1	CDK1	HPRD	empirical	11901153 8034666
LMNB1	MELK	HPRD	empirical	16216881