LAMC1
| Gene Description: |
laminin, gamma 1 (formerly LAMB2); laminin, gamma 1 |
| Synonyms: |
LAMC1, B2e, Lamc1, Lamb2, MGC87297, LAMB2 |
| Orthologs: |
Human LAMC1 (protein-coding), Mouse Lamc1 (protein-coding), Rat Lamc1 (protein-coding)
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Sources
Sources
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Human-Mouse:
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HomoloGene, MGD, RGD, Inparanoid, KEGG
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Human-Rat:
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HomoloGene, MGD, RGD, Inparanoid, KEGG
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Mouse-Rat:
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HomoloGene, MGD, RGD, Inparanoid, KEGG
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Possible sources:
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HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG
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Regions of Interest Overlapping this feature from T1DBase
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Regions Overlapping this Feature:
Mouse: 2
Linkage Regions: Available
Gene Overview from T1DBase
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Beta Cell Gene Atlas from T1DBase
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| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray
data generated with pancreatic beta cells and related cell lines and types. The
expression data comes from 131 array analyses derived from 28 experiments
(open details in a new window).
The basal (untreated cell) expression signal intensity values in each array
were converted to ranks within the experiments; the highest value was used for
genes represented by more than one probe. The rank values of genes in a given cell
type were averaged with other calculated values from experiments performed with the
same cell type. The rank transformation of the expression values enable comparison
of gene expression across different organisms and tissues.
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A red border around a cell indicates greater certainty in the data;
specifically, the gene has >0.95 probability of being expressed in the tissue.
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| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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Expression Legend
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Signal intensity values were converted to ranks within the experiments.
For genes represented by more than one probeset, we averaged the intensity
signals for each probeset across all tissues and chose the probeset with the
highest average value. The rank transformation of the expression values enables
comparison of gene expression across different organisms and tissues.
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No HaemAtlas Expression pattern available for this gene.
Interactions Table for LAMC1:
The LAMC1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
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Cross-Reference to Pathways and GO Terms
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KEGG Network: 7
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Biocarta: 1
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Reactome: 3
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NCI-Nature Pathway Interaction Database: 5
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Gene Ontology: 17
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Type 1 Diabetes Publications: 1
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Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine background.
Cha S, Nagashima H, Brown VB, Peck AB, Humphreys-Beher MG
Arthritis Rheum. 2002
PubMed ID: 12115247
Publications: 212
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Regional differences in the expression of laminin isoforms during mouse neural tube development.
Copp AJ, Carvalho R, Wallace A, Sorokin L, Sasaki T, Greene ND, Ybot-Gonzalez P
Matrix Biol. 2011
PubMed ID: 21524702
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The basement membrane of hair follicle stem cells is a muscle cell niche.
Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM
Cell. 2011
PubMed ID: 21335239
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Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.
Mokkapati S, Fleger-Weckmann A, Bechtel M, Koch M, Breitkreutz D, Mayer U, Smyth N, Nischt R
J Biol Chem. 2011
PubMed ID: 21084308
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Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
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Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.
Beraldo FH, Arantes CP, Santos TG, Machado CF, Roffe M, Hajj GN, Lee KS, Magalhães AC, Caetano FA, Mancini GL, Lopes MH, Américo TA, Magdesian MH, Ferguson SS, Linden R, Prado MA, Martins VR
FASEB J. 2011
PubMed ID: 20876210
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Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking.
Kalkhof S, Haehn S, Paulsson M, Smyth N, Meiler J, Sinz A
Proteins. 2010
PubMed ID: 20939100
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Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells.
Grimal S, Puech S, Wagener R, Ventéo S, Carroll P, Fichard-Carroll A
Glia. 2010
PubMed ID: 20830809
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A novel disulfide pattern in laminin-type epidermal growth factor-like (LE) modules of laminin β1 and γ1 chains.
Kalkhof S, Witte K, Ihling CH, Müller MQ, Keller MV, Haehn S, Smyth N, Paulsson M, Sinz A
Biochemistry. 2010
PubMed ID: 20731416
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Nano-structure of the laminin γ-1 short arm reveals an extended and curved multidomain assembly.
Patel TR, Morris GA, Zwolanek D, Keene DR, Li J, Harding SE, Koch M, Stetefeld J
Matrix Biol. 2010
PubMed ID: 20688161
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Laminin-121--recombinant expression and interactions with integrins.
Sasaki T, Takagi J, Giudici C, Yamada Y, Arikawa-Hirasawa E, Deutzmann R, Timpl R, Sonnenberg A, Bächinger HP, Tonge D
Matrix Biol. 2010
PubMed ID: 20566382
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Is laminin gamma-1 a candidate gene for advanced pelvic organ prolapse?
Chen C, Hill LD, Schubert CM, Strauss JF, Matthews CA
Am J Obstet Gynecol. 2010
PubMed ID: 20223449
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Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A.
Abrass CK, Hansen KM
J Biol Chem. 2010
PubMed ID: 20167606
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Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G, Ovarian Cancer Association Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer)
PLoS Genet. 2010
PubMed ID: 20628624
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The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.
Rajagopal R, Huang J, Dattilo LK, Kaartinen V, Mishina Y, Deng CX, Umans L, Zwijsen A, Roberts AB, Beebe DC
Dev Biol. 2009
PubMed ID: 19733164
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Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
Wheeler HE, Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK
PLoS Genet. 2009
PubMed ID: 19834535
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Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.
Yu WM, Yu H, Chen ZL, Strickland S
Glia. 2009
PubMed ID: 19053061
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Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.
Rooney JE, Gurpur PB, Burkin DJ
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19416897
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Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
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Laminin is required for Schwann cell morphogenesis.
Yu WM, Chen ZL, North AJ, Strickland S
J Cell Sci. 2009
PubMed ID: 19295124
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Cortical deficiency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration.
Chen ZL, Haegeli V, Yu H, Strickland S
Dev Biol. 2009
PubMed ID: 19118544
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Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells.
Staquicini FI, Dias-Neto E, Li J, Snyder EY, Sidman RL, Pasqualini R, Arap W
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19193855
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Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
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Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.
Ichikawa N, Iwabuchi K, Kurihara H, Ishii K, Kobayashi T, Sasaki T, Hattori N, Mizuno Y, Hozumi K, Yamada Y, Arikawa-Hirasawa E
J Cell Sci. 2009
PubMed ID: 19118221
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Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.
Rooney JE, Gurpur PB, Yablonka-Reuveni Z, Burkin DJ
Am J Pathol. 2009
PubMed ID: 19074617
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Lack of laminin gamma1 in embryonic stem cell-derived cardiomyocytes causes inhomogeneous electrical spreading despite intact differentiation and function.
Malan D, Reppel M, Dobrowolski R, Roell W, Smyth N, Hescheler J, Paulsson M, Bloch W, Fleischmann BK
Stem Cells. 2009
PubMed ID: 18927478
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Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor.
Chen ZL, Yu H, Yu WM, Pawlak R, Strickland S
J Cell Biol. 2008
PubMed ID: 19114596
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Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains.
Ido H, Ito S, Taniguchi Y, Hayashi M, Sato-Nishiuchi R, Sanzen N, Hayashi Y, Futaki S, Sekiguchi K
J Biol Chem. 2008
PubMed ID: 18697739
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
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Transcriptome-based systematic identification of extracellular matrix proteins.
Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18757743
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Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.
Plantman S, Patarroyo M, Fried K, Domogatskaya A, Tryggvason K, Hammarberg H, Cullheim S
Mol Cell Neurosci. 2008
PubMed ID: 18590826
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Basement membranes in skin are differently affected by lack of nidogen 1 and 2.
Mokkapati S, Baranowsky A, Mirancea N, Smyth N, Breitkreutz D, Nischt R
J Invest Dermatol. 2008
PubMed ID: 18356808
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Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow.
Jakobsson L, Domogatskaya A, Tryggvason K, Edgar D, Claesson-Welsh L
FASEB J. 2008
PubMed ID: 18073332
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Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.
Inoue T, Ogawa M, Mikoshiba K, Aruga J
J Neurosci. 2008
PubMed ID: 18448648
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GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
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Transcription of laminin gamma1 chain gene in rat mesangial cells: constitutive and inducible RNA polymerase II recruitment and chromatin states.
Nelson JD, Flanagin S, Kawata Y, Denisenko O, Bomsztyk K
Am J Physiol Renal Physiol. 2008
PubMed ID: 18184742
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Toward a confocal subcellular atlas of the human proteome.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Mol Cell Proteomics. 2008
PubMed ID: 18029348
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The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex.
Costa MR, Kessaris N, Richardson WD, Götz M, Hedin-Pereira C
J Neurosci. 2007
PubMed ID: 17942732
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Regulation of mesodermal differentiation of mouse embryonic stem cells by basement membranes.
Fujiwara H, Hayashi Y, Sanzen N, Kobayashi R, Weber CN, Emoto T, Futaki S, Niwa H, Murray P, Edgar D, Sekiguchi K
J Biol Chem. 2007
PubMed ID: 17690109
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Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti-oxidant alpha-lipoic acid.
Singh LP, Cheng DW, Kowluru R, Levi E, Jiang Y
Cell Biochem Funct. 2007
PubMed ID: 16892452
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Binding of netrin-4 to laminin short arms regulates basement membrane assembly.
Schneiders FI, Maertens B, Böse K, Li Y, Brunken WJ, Paulsson M, Smyth N, Koch M
J Biol Chem. 2007
PubMed ID: 17588941
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Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.
Rebustini IT, Patel VN, Stewart JS, Layvey A, Georges-Labouesse E, Miner JH, Hoffman MP
Dev Biol. 2007
PubMed ID: 17601529
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Role of laminin terminal globular domains in basement membrane assembly.
McKee KK, Harrison D, Capizzi S, Yurchenco PD
J Biol Chem. 2007
PubMed ID: 17517882
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Selective overexpression of gamma1 laminin in astrocytes in amyotrophic lateral sclerosis indicates an involvement in ALS pathology.
Wiksten M, Väänänen A, Liesi P
J Neurosci Res. 2007
PubMed ID: 17554784
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Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.
Kiyozumi D, Sugimoto N, Nakano I, Sekiguchi K
Matrix Biol. 2007
PubMed ID: 17462874
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Sequence variant in the laminin gamma1 (LAMC1) gene associated with familial pelvic organ prolapse.
Nikolova G, Lee H, Berkovitz S, Nelson S, Sinsheimer J, Vilain E, Rodríguez LV
Hum Genet. 2007
PubMed ID: 17021862
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MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system.
Brandt-Bohne U, Keene DR, White FA, Koch M
Biochem J. 2007
PubMed ID: 16981854
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The consensus coding sequences of human breast and colorectal cancers.
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE
Science. 2006
PubMed ID: 16959974
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Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.
Kiyozumi D, Sugimoto N, Sekiguchi K
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16880404
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Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes.
Haubst N, Georges-Labouesse E, De Arcangelis A, Mayer U, Götz M
Development. 2006
PubMed ID: 16873583
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Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.
Kikkawa Y, Miner JH
Dev Biol. 2006
PubMed ID: 16750824
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The DNA sequence and biological annotation of human chromosome 1.
Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E
Nature. 2006
PubMed ID: 16710414
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Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.
Bajanca F, Luz M, Raymond K, Martins GG, Sonnenberg A, Tajbakhsh S, Buckingham M, Thorsteinsdóttir S
Development. 2006
PubMed ID: 16554364
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
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Large-scale identification of genes implicated in kidney glomerulus development and function.
Takemoto M, He L, Norlin J, Patrakka J, Xiao Z, Petrova T, Bondjers C, Asp J, Wallgard E, Sun Y, Samuelsson T, Mostad P, Lundin S, Miura N, Sado Y, Alitalo K, Quaggin SE, Tryggvason K, Betsholtz C
EMBO J. 2006
PubMed ID: 16498405
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Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells.
Vainionpää N, Kikkawa Y, Lounatmaa K, Miner JH, Rousselle P, Virtanen I
Am J Physiol Cell Physiol. 2006
PubMed ID: 16236823
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Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
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Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.
Grote D, Souabni A, Busslinger M, Bouchard M
Development. 2006
PubMed ID: 16319112
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Changes in laminin isoforms associated with brain tumor invasion and angiogenesis.
Ljubimova JY, Fujita M, Khazenzon NM, Ljubimov AV, Black KL
Front Biosci. 2006
PubMed ID: 16146715
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Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD
J Proteome Res. 2005
PubMed ID: 16335952
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Generation of a conditionally null allele of the laminin alpha1 gene.
Alpy F, Jivkov I, Sorokin L, Klein A, Arnold C, Huss Y, Kedinger M, Simon-Assmann P, Lefebvre O
Genesis. 2005
PubMed ID: 16100707
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A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
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Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
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Science. 2005
PubMed ID: 16141072
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Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.
Bader BL, Smyth N, Nedbal S, Miosge N, Baranowsky A, Mokkapati S, Murshed M, Nischt R
Mol Cell Biol. 2005
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Basement membrane composition in the early mouse embryo day 7.
Gersdorff N, Müller M, Otto S, Poschadel R, Hübner S, Miosge N
Dev Dyn. 2005
PubMed ID: 15895400
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Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.
Kiyozumi D, Osada A, Sugimoto N, Weber CN, Ono Y, Imai T, Okada A, Sekiguchi K
Exp Cell Res. 2005
PubMed ID: 15878328
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Schwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation.
Yu WM, Feltri ML, Wrabetz L, Strickland S, Chen ZL
J Neurosci. 2005
PubMed ID: 15872093
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Laminin-sulfatide binding initiates basement membrane assembly and enables receptor signaling in Schwann cells and fibroblasts.
Li S, Liquari P, McKee KK, Harrison D, Patel R, Lee S, Yurchenco PD
J Cell Biol. 2005
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Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration.
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Neoplasia. 2005
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Basement membrane-dependent survival of retinal ganglion cells.
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Invest Ophthalmol Vis Sci. 2005
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Expression of MAEG, a novel basement membrane protein, in mouse hair follicle morphogenesis.
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Exp Cell Res. 2005
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The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
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Exp Cell Res. 2005
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Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice.
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Proc Natl Acad Sci U S A. 2004
PubMed ID: 15377789
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Functional proteomics mapping of a human signaling pathway.
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Genome Res. 2004
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The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens.
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Dev Biol. 2004
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Evaluation of the ARMD1 locus on 1q25-31 in patients with age-related maculopathy: genetic variation in laminin genes and in exon 104 of HEMICENTIN-1.
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Ophthalmic Genet. 2004
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Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.
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Nat Biotechnol. 2004
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Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures.
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J Cell Sci. 2004
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Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation.
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Development. 2004
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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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Nature. 2004
PubMed ID: 15057822
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Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.
Pöschl E, Schlötzer-Schrehardt U, Brachvogel B, Saito K, Ninomiya Y, Mayer U
Development. 2004
PubMed ID: 14998921
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A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.
Takamiya K, Kostourou V, Adams S, Jadeja S, Chalepakis G, Scambler PJ, Huganir RL, Adams RH
Nat Genet. 2004
PubMed ID: 14730302
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Elimination by necrosis, not apoptosis, of embryonic extraocular muscles in the muscular dysgenesis mutant of the mouse.
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Cell Tissue Res. 2004
PubMed ID: 14618389
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GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Visel A, Thaller C, Eichele G
Nucleic Acids Res. 2004
PubMed ID: 14681479
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
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Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve.
Chen ZL, Strickland S
J Cell Biol. 2003
PubMed ID: 14638863
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Laminin isoforms in fetal and adult human adrenal cortex.
Virtanen I, Korhonen M, Petäjäniemi N, Karhunen T, Thornell LE, Sorokin LM, Konttinen YT
J Clin Endocrinol Metab. 2003
PubMed ID: 14557481
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Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface.
Takagi J, Yang Y, Liu JH, Wang JH, Springer TA
Nature. 2003
PubMed ID: 12931195
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A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
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Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.
Yin Y, Kikkawa Y, Mudd JL, Skarnes WC, Sanes JR, Miner JH
Genesis. 2003
PubMed ID: 12820173
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Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
Zhang H, Li XJ, Martin DB, Aebersold R
Nat Biotechnol. 2003
PubMed ID: 12754519
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Laminin-10 is crucial for hair morphogenesis.
Li J, Tzu J, Chen Y, Zhang YP, Nguyen NT, Gao J, Bradley M, Keene DR, Oro AE, Miner JH, Marinkovich MP
EMBO J. 2003
PubMed ID: 12743034
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A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3.
Yuan W, Rao Y, Babiuk RP, Greer JJ, Wu JY, Ornitz DM
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12702769
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Increased Sp1-dependent transactivation of the LAMgamma 1 promoter in hepatic stellate cells co-cultured with HepG2 cells overexpressing cytochrome P450 2E1.
Nieto N, Cederbaum AI
J Biol Chem. 2003
PubMed ID: 12529372
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Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.
Kikkawa Y, Virtanen I, Miner JH
J Cell Biol. 2003
PubMed ID: 12682087
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An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients.
Inagaki J, Sugiura-Ogasawara M, Nomizu M, Nakatsuka M, Ikuta K, Suzuki N, Kaihara K, Kobayashi K, Yasuda T, Shoenfeld Y, Aoki K, Matsuura E
Hum Reprod. 2003
PubMed ID: 12615822
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Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.
Smits P, Lefebvre V
Development. 2003
PubMed ID: 12571105
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Gamma 1 laminin and its biologically active KDI-domain may guide axons in the floor plate of human embryonic spinal cord.
Wiksten M, Liebkind R, Laatikainen T, Liesi P
J Neurosci Res. 2003
PubMed ID: 12526023
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BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
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Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
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Nature. 2002
PubMed ID: 12466851
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Initial sequencing and comparative analysis of the mouse genome.
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Nature. 2002
PubMed ID: 12466850
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Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice.
Kirstein SL, Davidson KL, Ehringer MA, Sikela JM, Erwin VG, Tabakoff B
J Pharmacol Exp Ther. 2002
PubMed ID: 12183685
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A critical function of the pial basement membrane in cortical histogenesis.
Halfter W, Dong S, Yip YP, Willem M, Mayer U
J Neurosci. 2002
PubMed ID: 12122064
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Differential distribution of laminins in Alzheimer disease and normal human brain tissue.
Palu E, Liesi P
J Neurosci Res. 2002
PubMed ID: 12111806
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Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.
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Dev Biol. 2002
PubMed ID: 12051813
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Synergistic activation of the rat laminin gamma1 chain promoter by the gut-enriched Kruppel-like factor (GKLF/KLF4) and Sp1.
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Nucleic Acids Res. 2002
PubMed ID: 12034813
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Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.
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Development. 2002
PubMed ID: 12015298
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Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways.
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J Biol Chem. 2002
PubMed ID: 11891225
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Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.
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Exp Cell Res. 2002
PubMed ID: 11969289
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bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteins.
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J Biol Chem. 2002
PubMed ID: 11801598
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Developmentally regulated expression of type XV collagen correlates with abnormalities in Col15a1(-/-) mice.
Muona A, Eklund L, Väisänen T, Pihlajaniemi T
Matrix Biol. 2002
PubMed ID: 11827796
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Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.
Klaffky E, Williams R, Yao CC, Ziober B, Kramer R, Sutherland A
Dev Biol. 2001
PubMed ID: 11784026
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Functional analysis of secreted and transmembrane proteins critical to mouse development.
Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, Scherz P, Leighton PA, Goodrich LV, Lu X, Avery BJ, Tate P, Dill K, Pangilinan E, Wakenight P, Tessier-Lavigne M, Skarnes WC
Nat Genet. 2001
PubMed ID: 11431694
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Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.
McArthur CP, Wang Y, Heruth D, Gustafson S
Arch Oral Biol. 2001
PubMed ID: 11311202
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Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
-
Lutheran blood group glycoprotein and its newly characterized mouse homologue specifically bind alpha5 chain-containing human laminin with high affinity.
Parsons SF, Lee G, Spring FA, Willig TN, Peters LL, Gimm JA, Tanner MJ, Mohandas N, Anstee DJ, Chasis JA
Blood. 2001
PubMed ID: 11133776
-
Monocytic cells synthesize, adhere to, and migrate on laminin-8 (alpha 4 beta 1 gamma 1).
Pedraza C, Geberhiwot T, Ingerpuu S, Assefa D, Wondimu Z, Kortesmaa J, Tryggvason K, Virtanen I, Patarroyo M
J Immunol. 2000
PubMed ID: 11067943
-
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
-
Integrins as receptors for laminins.
Belkin AM, Stepp MA
Microsc Res Tech. 2000
PubMed ID: 11054877
-
Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG
Mech Dev. 2000
PubMed ID: 11044609
-
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
-
Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.
Champliaud MF, Virtanen I, Tiger CF, Korhonen M, Burgeson R, Gullberg D
Exp Cell Res. 2000
PubMed ID: 10964500
-
Regulation of programmed cell death by basement membranes in embryonic development.
Murray P, Edgar D
J Cell Biol. 2000
PubMed ID: 10974008
-
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
-
Mice lacking Dad1, the defender against apoptotic death-1, express abnormal N-linked glycoproteins and undergo increased embryonic apoptosis.
Hong NA, Flannery M, Hsieh SN, Cado D, Pedersen R, Winoto A
Dev Biol. 2000
PubMed ID: 10720432
-
Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins.
Kikkawa Y, Sanzen N, Fujiwara H, Sonnenberg A, Sekiguchi K
J Cell Sci. 2000
PubMed ID: 10671376
-
Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.
Miner JH, Li C
Dev Biol. 2000
PubMed ID: 10625553
-
A comparative gene map of the horse (Equus caballus).
Caetano AR, Shiue YL, Lyons LA, O'Brien SJ, Laughlin TF, Bowling AT, Murray JD
Genome Res. 1999
PubMed ID: 10613847
-
Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification.
Barbacci E, Reber M, Ott MO, Breillat C, Huetz F, Cereghini S
Development. 1999
PubMed ID: 10518496
-
Laminin-11.
Miner JH, Patton BL
Int J Biochem Cell Biol. 1999
PubMed ID: 10481268
-
An integrated somatic cell hybrid, YAC, and BAC map of the Rmc1 region of mouse chromosome 1.
Hunter K, Greenwood J, Yang YL, Cunningham JM, Birren B, Housman D
Genomics. 1999
PubMed ID: 10373331
-
Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses.
Tailor CS, Nouri A, Lee CG, Kozak C, Kabat D
Proc Natl Acad Sci U S A. 1999
PubMed ID: 9927670
-
Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1.
Yang YL, Guo L, Xu S, Holland CA, Kitamura T, Hunter K, Cunningham JM
Nat Genet. 1999
PubMed ID: 9988277
-
Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation.
Smyth N, Vatansever HS, Murray P, Meyer M, Frie C, Paulsson M, Edgar D
J Cell Biol. 1999
PubMed ID: 9885251
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
-
Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.
Miner JH, Cunningham J, Sanes JR
J Cell Biol. 1998
PubMed ID: 9852162
-
Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.
Godfrey EW, Gradall KS
Anat Embryol (Berl). 1998
PubMed ID: 9833687
-
Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.
Bader BL, Rayburn H, Crowley D, Hynes RO
Cell. 1998
PubMed ID: 9827803
-
Inducible transcriptional activity of bcn-1 element from laminin gamma1-chain gene promoter in renal and nonrenal cells.
Suzuki H, Denisenko ON, Suzuki Y, Schullery DS, Bomsztyk K
Am J Physiol. 1998
PubMed ID: 9755123
-
Nidogen-2: a new basement membrane protein with diverse binding properties.
Kohfeldt E, Sasaki T, Göhring W, Timpl R
J Mol Biol. 1998
PubMed ID: 9733643
-
Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.
Sahlberg C, Hormia M, Airenne T, Thesleff I
J Dent Res. 1998
PubMed ID: 9719032
-
The laminin-nidogen complex is a ligand for a specific splice isoform of the transmembrane protein tyrosine phosphatase LAR.
O'Grady P, Thai TC, Saito H
J Cell Biol. 1998
PubMed ID: 9647658
-
Three-dimensional analysis of the developing pituitary gland in the mouse.
Hashimoto H, Ishikawa H, Kusakabe M
Dev Dyn. 1998
PubMed ID: 9603432
-
Expression and localization of laminin-5 subunits in the mouse incisor.
Yoshiba N, Yoshiba K, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H
Cell Tissue Res. 1998
PubMed ID: 9506922
-
Expression and localization of laminin-5 subunits during mouse tooth development.
Yoshiba K, Yoshiba N, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H
Dev Dyn. 1998
PubMed ID: 9489770
-
Identification of cell binding sequences in mouse laminin gamma1 chain by systematic peptide screening.
Nomizu M, Kuratomi Y, Song SY, Ponce ML, Hoffman MP, Powell SK, Miyoshi K, Otaka A, Kleinman HK, Yamada Y
J Biol Chem. 1997
PubMed ID: 9405421
-
Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.
Patton BL, Miner JH, Chiu AY, Sanes JR
J Cell Biol. 1997
PubMed ID: 9396756
-
Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice.
Tiger CF, Gullberg D
Muscle Nerve. 1997
PubMed ID: 9390664
-
Laminin chain-specific gene expression during mouse oocyte maturation.
Shim C, Lee SG, Song WK, Lee CS, Lee KK, Kim K
Mol Reprod Dev. 1997
PubMed ID: 9291468
-
Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.
Sorokin LM, Pausch F, Frieser M, Kröger S, Ohage E, Deutzmann R
Dev Biol. 1997
PubMed ID: 9299121
-
Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.
Qin P, Piechocki M, Lu S, Kurpakus MA
Dev Dyn. 1997
PubMed ID: 9264260
-
Extracellular-matrix gene expression during mouse submandibular gland development.
Macauley SP, Tarnuzzer RW, Schultz GS, Chegini N, Oxford GE, Humphreys-Beher MG
Arch Oral Biol. 1997
PubMed ID: 9382709
-
Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.
Lentz SI, Miner JH, Sanes JR, Snider WD
J Comp Neurol. 1997
PubMed ID: 9034910
-
Importance of nidogen binding to laminin gamma1 for branching epithelial morphogenesis of the submandibular gland.
Kadoya Y, Salmivirta K, Talts JF, Kadoya K, Mayer U, Timpl R, Ekblom P
Development. 1997
PubMed ID: 9043083
-
Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice.
Rothman TP, Chen J, Howard MJ, Costantini F, Schuchardt A, Pachnis V, Gershon MD
Dev Biol. 1996
PubMed ID: 8812145
-
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
-
Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.
Yotsumoto S, Fujiwara H, Horton JH, Mosby TA, Wang X, Cui Y, Ko MS
Hum Mol Genet. 1996
PubMed ID: 8872465
-
Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis.
Wu JE, Santoro SA
Dev Dyn. 1996
PubMed ID: 8725284
-
Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition.
Orian-Rousseau V, Aberdam D, Fontao L, Chevalier L, Meneguzzi G, Kedinger M, Simon-Assmann P
Dev Dyn. 1996
PubMed ID: 9019243
-
Differential expression of laminin chain-specific mRNA transcripts during mouse preimplantation embryo development.
Shim C, Kwon HB, Kim K
Mol Reprod Dev. 1996
PubMed ID: 8722691
-
Structure of the nidogen binding LE module of the laminin gamma1 chain in solution.
Baumgartner R, Czisch M, Mayer U, Pöschl E, Huber R, Timpl R, Holak TA
J Mol Biol. 1996
PubMed ID: 8648631
-
Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site.
Stetefeld J, Mayer U, Timpl R, Huber R
J Mol Biol. 1996
PubMed ID: 8648630
-
Positive elements in the laminin gamma 1 gene synergize to activate high level transcription during cellular differentiation.
Chang HS, Kim NB, Phillips SL
Nucleic Acids Res. 1996
PubMed ID: 8614642
-
Carboxy terminal sequence and synthesis of rat kidney laminin gamma 1 chain.
Vanden Heuvel GB, Leardkamolkarn V, St John PL, Abrahamson DR
Kidney Int. 1996
PubMed ID: 8648916
-
Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.
Schuler F, Sorokin LM
J Cell Sci. 1995
PubMed ID: 8719886
-
Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections.
Morissette N, Carbonetto S
J Neurosci. 1995
PubMed ID: 8613743
-
Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.
Enders GC, Kahsai TZ, Lian G, Funabiki K, Killen PD, Hudson BG
Biol Reprod. 1995
PubMed ID: 8562707
-
Four loci from human chromosome 1 are physically assigned to sheep chromosome 1p.
Broad TE, Burkin DJ, Cambridge LM, Carpenter MA, Jones C
Mamm Genome. 1995
PubMed ID: 8589528
-
The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.
Noakes PG, Miner JH, Gautam M, Cunningham JM, Sanes JR, Merlie JP
Nat Genet. 1995
PubMed ID: 7670489
-
Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.
Stephens LE, Sutherland AE, Klimanskaya IV, Andrieux A, Meneses J, Pedersen RA, Damsky CH
Genes Dev. 1995
PubMed ID: 7544312
-
Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.
Fröjdman K, Ekblom P, Sorokin L, Yagi A, Pelliniemi LJ
Int J Dev Biol. 1995
PubMed ID: 7669546
-
Cloning and expression of the mouse laminin gamma 2 (B2t) chain, a subunit of epithelial cell laminin.
Sugiyama S, Utani A, Yamada S, Kozak CA, Yamada Y
Eur J Biochem. 1995
PubMed ID: 7882992
-
Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart.
Zhang HY, Chu ML, Pan TC, Sasaki T, Timpl R, Ekblom P
Dev Biol. 1995
PubMed ID: 7851641
-
Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.
Wewer UM, Gerecke DR, Durkin ME, Kurtz KS, Mattei MG, Champliaud MF, Burgeson RE, Albrechtsen R
Genomics. 1994
PubMed ID: 7698745
-
Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.
Utani A, Nomizu M, Timpl R, Roller PP, Yamada Y
J Biol Chem. 1994
PubMed ID: 8034675
-
Expression of novel 400-kDa laminin chains by mouse and bovine endothelial cells.
Sorokin L, Girg W, Göpfert T, Hallmann R, Deutzmann R
Eur J Biochem. 1994
PubMed ID: 8055931
-
A new nomenclature for the laminins.
Burgeson RE, Chiquet M, Deutzmann R, Ekblom P, Engel J, Kleinman H, Martin GR, Meneguzzi G, Paulsson M, Sanes J
Matrix Biol. 1994
PubMed ID: 7921537
-
Expression of laminin chains during myogenic differentiation.
Kroll TG, Peters BP, Hustad CM, Jones PA, Killen PD, Ruddon RW
J Biol Chem. 1994
PubMed ID: 7510707
-
Expression of collagen alpha 1(IV), laminin and nidogen genes in the embryonic mouse lung: implications for branching morphogenesis.
Thomas T, Dziadek M
Mech Dev. 1994
PubMed ID: 7516699
-
Expression of laminin and nidogen genes during the postimplantation development of the mouse placenta.
Thomas T, Dziadek M
Biol Reprod. 1993
PubMed ID: 8286607
-
Differential expression of laminin, nidogen and collagen IV genes in the midgestation mouse placenta.
Thomas T, Dziadek M
Placenta. 1993
PubMed ID: 8153091
-
Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo.
Thomas T, Dziadek M
Exp Cell Res. 1993
PubMed ID: 8359228
-
The dermal-epidermal junction of human skin contains a novel laminin variant.
Marinkovich MP, Lunstrum GP, Keene DR, Burgeson RE
J Cell Biol. 1992
PubMed ID: 1383241
-
Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.
Schuger L, Varani J, Killen PD, Skubitz AP, Gilbride K
Dev Dyn. 1992
PubMed ID: 1292752
-
Polymorphisms revealed by PCR with single, short-sized, arbitrary primers are reliable markers for mouse and rat gene mapping.
Serikawa T, Montagutelli X, Simon-Chazottes D, Guénet JL
Mamm Genome. 1992
PubMed ID: 1617216
-
Genetic linkage analysis in recombinant inbred mice of P40, a putative clone for the high-affinity laminin receptor.
Douville PJ, Carbonetto S
Mamm Genome. 1992
PubMed ID: 1353694
-
The expression of the genes for entactin, laminin A, laminin B1 and laminin B2 in murine lens morphogenesis and eye development.
Dong LJ, Chung AE
Differentiation. 1991
PubMed ID: 1725162
-
Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.
Schuger L, Skubitz AP, O'Shea KS, Chang JF, Varani J
Dev Biol. 1991
PubMed ID: 1907584
-
Rat pineal gland phosducin: cDNA isolation, nucleotide sequence, and chromosomal assignment in the mouse.
Craft CM, Lolley RN, Seldin MF, Lee RH
Genomics. 1991
PubMed ID: 2071146
-
Structure of the human laminin B2 chain gene reveals extensive divergence from the laminin B1 chain gene.
Kallunki T, Ikonen J, Chow LT, Kallunki P, Tryggvason K
J Biol Chem. 1991
PubMed ID: 1985895
-
Differences in human laminin B2 sequences.
Santos CL, Sabbaga J, Brentani R
DNA Seq. 1991
PubMed ID: 1806043
-
The gene for retinal rod 33-kDa protein is on mouse chromosome 1, near Lamb2.
Danciger M, Kozak CA, Abe T, Shinohara T, Farber DB
Cytogenet Cell Genet. 1991
PubMed ID: 1675982
-
Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.
Kücherer-Ehret A, Pottgiesser J, Kreutzberg GW, Thoenen H, Edgar D
Development. 1990
PubMed ID: 2100263
-
Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids.
Kaye NW, Chung AE, Lalley PA, Durkin ME, Phillips SL, Church RL
Somat Cell Mol Genet. 1990
PubMed ID: 2267633
-
Differential expression of laminin A and B chains during development of embryonic mouse organs.
Klein G, Ekblom M, Fecker L, Timpl R, Ekblom P
Development. 1990
PubMed ID: 2088723
-
Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1.
Moseley WS, Seldin MF
Genomics. 1989
PubMed ID: 2574151
-
The isolation and characterization of the murine T cell antigen receptor zeta chain gene.
Baniyash M, Hsu VW, Seldin MF, Klausner RD
J Biol Chem. 1989
PubMed ID: 2787796
-
Sequence and organization of the mouse poly (ADP-ribose) polymerase gene.
Huppi K, Bhatia K, Siwarski D, Klinman D, Cherney B, Smulson M
Nucleic Acids Res. 1989
PubMed ID: 2498841
-
A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction.
Hunter DD, Shah V, Merlie JP, Sanes JR
Nature. 1989
PubMed ID: 2922051
-
Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross.
Seldin MF, Kruh GD
Genomics. 1989
PubMed ID: 2567701
-
Primary structure of the mouse laminin B2 chain and comparison with laminin B1.
Durkin ME, Bartos BB, Liu SH, Phillips SL, Chung AE
Biochemistry. 1988
PubMed ID: 3167041
-
cDNA cloning, expression and mapping of human laminin B2 gene to chromosome 1q31.
Mattei MG, Weil D, Pribula-Conway D, Bernard MP, Passage E, Van Cong N, Timpl R, Chu ML
Hum Genet. 1988
PubMed ID: 3402995
-
The laminin B2 chain promoter contains unique repeat sequences and is active in transient transfection.
Ogawa K, Burbelo PD, Sasaki M, Yamada Y
J Biol Chem. 1988
PubMed ID: 2836421
-
Human laminin B2 chain. Comparison of the complete amino acid sequence with the B1 chain reveals variability in sequence homology between different structural domains.
Pikkarainen T, Kallunki T, Tryggvason K
J Biol Chem. 1988
PubMed ID: 3360804
-
Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q.
Seldin MF, Morse HC, LeBoeuf RC, Steinberg AD
Genomics. 1988
PubMed ID: 3384439
-
Isolation of a human laminin B2 (LAMB2) cDNA clone and assignment of the gene to chromosome region 1q25----q31.
Fukushima Y, Pikkarainen T, Kallunki T, Eddy RL, Byers MG, Haley LL, Henry WM, Tryggvason K, Shows TB
Cytogenet Cell Genet. 1988
PubMed ID: 3234037
-
The laminin B2 chain has a multidomain structure homologous to the B1 chain.
Sasaki M, Yamada Y
J Biol Chem. 1987
PubMed ID: 3680290
-
Structure of human tumor necrosis factor alpha derived from recombinant DNA.
Davis JM, Narachi MA, Alton NK, Arakawa T
Biochemistry. 1987
PubMed ID: 3552045
-
A mouse homeo box-containing gene maps near a developmental mutation.
Hill RE, Hall AE, Sime CM, Hastie ND
Cytogenet Cell Genet. 1987
PubMed ID: 2882954
-
Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.
Elliott RW, Barlow D, Hogan BL
In Vitro Cell Dev Biol. 1985
PubMed ID: 2993224
-
Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.
Barlow DP, Green NM, Kurkinen M, Hogan BL
EMBO J. 1984
PubMed ID: 6209134
Model Organism Phenotype Links
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This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network
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Relevant resources:
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