T1DBase - A Bioinformatics Resource for Type 1 Diabetes Researchers

Gene Description:

RIKEN cDNA 4930431A04 gene; killer cell lectin-like receptor subfamily B, member 1

Synonyms:

hNKR-P1A, Nkrp1g, Klrb6, Klrb1, NKR-P1, Klrb1g, CLEC5B, CD161, Nkrp-1e, MGC138614, NKRP1A, Gm4696, NKR-P1A, NKR, Klrb1f, Klrb1d, 4930431A04Rik, Nkr-p1e, NKR-P1G, KLRB1

Orthologs:

Human KLRB1 (protein-coding), Mouse 4930431A04Rik (protein-coding), Rat Klrb1 (protein-coding)

Sources

Regions Overlapping this Feature: Human: 1 Mouse: 1 Rat: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
12p13.31	Human	chr12:9621533..9976156	0.35	35	rs4763879

Other Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Human 12p13.31 Orthologous Region	Rat	chr4:165560615..166552178	0.99	15
Human 12p13.31 Orthologous Region	Mouse	chr6:128489612..129269156	0.78	15

(Human) GRCh37 - chr12:9747147..9760497 (13.35 kb) View in Genome Browser

(Mouse) NCBIM37 - chr6:128656526..128673064 (16.54 kb) View in Genome Browser

(Rat) RGSC3.4 - chr4:166253201..166271896 (18.70 kb) View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas
					no data	no data	no data	no data	no data	no data	no data	no data

Expression Legend

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker	EB	MK	CD66b	CD14	CD19	CD8	CD4	CD56
Expression Pattern									HaemAtlasProfile

Expression Legend

Interactions Table for KLRB1:

View all

KEGG Network: 1

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 7

Publications: 47

Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1).
Kamishikiryo J, Fukuhara H, Okabe Y, Kuroki K, Maenaka K
J Biol Chem. 2011
PubMed ID: 21572041
Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse.
Kveberg L, Dai KZ, Inngjerdingen M, Brooks CG, Fossum S, Vaage JT
Immunogenetics. 2011
PubMed ID: 21409442
The number of CD161 positive Th17 cells are decreased in head and neck cancer patients.
Kesselring R, Thiel A, Pries R, Wollenberg B
Cell Immunol. 2011
PubMed ID: 21570678
Novel aspects of in vitro IL-2 or IFN-α enhanced NK cytotoxicity of healthy individuals based on NKG2D and CD161 NK cell receptor induction.
Konjević G, Mirjačić Martinović K, Vuletić A, Radenković S
Biomed Pharmacother. 2010
PubMed ID: 20800424
Characterization of alternatively spliced transcript variants of CLEC2D gene.
Germain C, Bihl F, Zahn S, Poupon G, Dumaurier MJ, Rampanarivo HH, Padkjær SB, Spee P, Braud VM
J Biol Chem. 2010
PubMed ID: 20843815
The complete inventory of receptors encoded by the rat natural killer cell gene complex.
Flornes LM, Nylenna Ø, Saether PC, Daws MR, Dissen E, Fossum S
Immunogenetics. 2010
PubMed ID: 20544345
CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC.
Maggi L, Santarlasci V, Capone M, Peired A, Frosali F, Crome SQ, Querci V, Fambrini M, Liotta F, Levings MK, Maggi E, Cosmi L, Romagnani S, Annunziato F
Eur J Immunol. 2010
PubMed ID: 20486123
CD161 receptor participates in both impairing NK cell cytotoxicity and the response to glycans and vimentin in patients with rheumatoid arthritis.
Richter J, Benson V, Grobarova V, Svoboda J, Vencovsky J, Svobodova R, Fiserova A
Clin Immunol. 2010
PubMed ID: 20359956
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes Immun. 2010
PubMed ID: 20237496
Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.
Billerbeck E, Kang YH, Walker L, Lockstone H, Grafmueller S, Fleming V, Flint J, Willberg CB, Bengsch B, Seigel B, Ramamurthy N, Zitzmann N, Barnes EJ, Thevanayagam J, Bhagwanani A, Leslie A, Oo YH, Kollnberger S, Bowness P, Drognitz O, Adams DH, Blum HE, Thimme R, Klenerman P
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20133607
Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.
Hoppenbrouwers IA, Aulchenko YS, Janssens AC, Ramagopalan SV, Broer L, Kayser M, Ebers GC, Oostra BA, van Duijn CM, Hintzen RQ
J Hum Genet. 2009
PubMed ID: 19834503
Distribution of several activating and inhibitory receptors on CD3-CD16+ NK cells and their correlation with NK cell function in healthy individuals.
Konjević G, Mirjacić Martinović K, Vuletić A, Jurisić V, Spuzić I
J Membr Biol. 2009
PubMed ID: 19711124
Risk alleles for multiple sclerosis in multiplex families.
D'Netto MJ, Ward H, Morrison KM, Ramagopalan SV, Dyment DA, DeLuca GC, Handunnetthi L, Sadovnick AD, Ebers GC
Neurology. 2009
PubMed ID: 19506219
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.
Kleinschek MA, Boniface K, Sadekova S, Grein J, Murphy EE, Turner SP, Raskin L, Desai B, Faubion WA, de Waal Malefyt R, Pierce RH, McClanahan T, Kastelein RA
J Exp Med. 2009
PubMed ID: 19273624
Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding.
Kveberg L, Dai KZ, Westgaard IH, Daws MR, Fossum S, Naper C, Vaage JT
Eur J Immunol. 2009
PubMed ID: 19130483
PILAR is a novel modulator of human T-cell expansion.
Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Engle XA, Rigby WF, Pioli PA, Guyre PM, Conejo-Garcia JR
Blood. 2008
PubMed ID: 18550855
Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.
Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F, Rodolico G, Querci V, Abbate G, Angeli R, Berrino L, Fambrini M, Caproni M, Tonelli F, Lazzeri E, Parronchi P, Liotta F, Maggi E, Romagnani S, Annunziato F
J Exp Med. 2008
PubMed ID: 18663128
Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells.
Rosen DB, Cao W, Avery DT, Tangye SG, Liu YJ, Houchins JP, Lanier LL
J Immunol. 2008
PubMed ID: 18453569
CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation.
Northfield JW, Kasprowicz V, Lucas M, Kersting N, Bengsh B, Kim A, Phillips RE, Walker BD, Thimme R, Lauer G, Klenerman P
Hepatology. 2008
PubMed ID: 18219672
Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Clr-b missing-self axis.
Voigt S, Mesci A, Ettinger J, Fine JH, Chen P, Chou W, Carlyle JR
Immunity. 2007
PubMed ID: 17462921
[Transcription of the KLRB1 gene is suppressed in human cancer tissues]
Pleshkan VV, Zinov'eva MV, Vinogradova TV, Sverdlov ED
Mol Gen Mikrobiol Virusol. 2007
PubMed ID: 18159636
Recognition of a carbohydrate xenoepitope by human NKRP1A (CD161).
Christiansen D, Mouhtouris E, Milland J, Zingoni A, Santoni A, Sandrin MS
Xenotransplantation. 2006
PubMed ID: 16925668
Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells.
Carlyle JR, Mesci A, Ljutic B, Belanger S, Tai LH, Rousselle E, Troke AD, Proteau MF, Makrigiannis AP
J Immunol. 2006
PubMed ID: 16751398
CD161 (human NKR-P1A) signaling in NK cells involves the activation of acid sphingomyelinase.
Pozo D, Valés-Gómez M, Mavaddat N, Williamson SC, Chisholm SE, Reyburn H
J Immunol. 2006
PubMed ID: 16455998
Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor.
Rosen DB, Bettadapura J, Alsharifi M, Mathew PA, Warren HS, Lanier LL
J Immunol. 2005
PubMed ID: 16339513
Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor.
Aldemir H, Prod'homme V, Dumaurier MJ, Retiere C, Poupon G, Cazareth J, Bihl F, Braud VM
J Immunol. 2005
PubMed ID: 16339512
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.
Carlyle JR, Jamieson AM, Gasser S, Clingan CS, Arase H, Raulet DH
Proc Natl Acad Sci U S A. 2004
PubMed ID: 14990792
Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors.
Iizuka K, Naidenko OV, Plougastel BF, Fremont DH, Yokoyama WM
Nat Immunol. 2003
PubMed ID: 12858173
Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease.
Smith FB, Connor JM, Lee AJ, Cooke A, Lowe GD, Rumley A, Fowkes FG
Thromb Res. 2003
PubMed ID: 14987913
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
CD161+ T (NT) cells exist predominantly in human intestinal epithelium as well as in liver.
Iiai T, Watanabe H, Suda T, Okamoto H, Abo T, Hatakeyama K
Clin Exp Immunol. 2002
PubMed ID: 12100027
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver.
Ishihara S, Nieda M, Kitayama J, Osada T, Yabe T, Ishikawa Y, Nagawa H, Muto T, Juji T
Eur J Immunol. 1999
PubMed ID: 10458753
Mouse NKR-P1B, a novel NK1.1 antigen with inhibitory function.
Carlyle JR, Martin A, Mehra A, Attisano L, Tsui FW, Zúñiga-Pflücker JC
J Immunol. 1999
PubMed ID: 10229828
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
IL-12-induced up-regulation of NKRP1A expression in human NK cells and consequent NKRP1A-mediated down-regulation of NK cell activation.
Poggi A, Costa P, Tomasello E, Moretta L
Eur J Immunol. 1998
PubMed ID: 9603467
Expression and function of NKRP1A molecule on human monocytes and dendritic cells.
Poggi A, Rubartelli A, Moretta L, Zocchi MR
Eur J Immunol. 1997
PubMed ID: 9394825
Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. Direct evidence that the NKRP1A molecule is involved in transendothelial migration.
Poggi A, Costa P, Zocchi MR, Moretta L
Eur J Immunol. 1997
PubMed ID: 9341779
The human natural killer gene complex is located on chromosome 12p12-p13.
Renedo M, Arce I, Rodríguez A, Carretero M, Lanier LL, López-Botet M, Fernández-Ruiz E
Immunogenetics. 1997
PubMed ID: 9218532
Expression of human NKRP1A by CD34+ immature thymocytes: NKRP1A-mediated regulation of proliferation and cytolytic activity.
Poggi A, Costa P, Morelli L, Cantoni C, Pella N, Spada F, Biassoni R, Nanni L, Revello V, Tomasello E, Mingari MC, Moretta A, Moretta L
Eur J Immunol. 1996
PubMed ID: 8647203
Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes.
Lanier LL, Chang C, Phillips JH
J Immunol. 1994
PubMed ID: 8077657

This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.

Organism	Phenotype	Resources
Mouse	MGI:96877	IKMC

	Human	Mouse	Rat
Entrez Gene	3820	100043861	689817
EnsEMBL Gene(s)	ENSG00000111796	ENSMUSG00000079299	ENSRNOG00000031072
Unigene	Hs.169824	Mm.66911	Rn.198693
Homologene	KLRB1	4930431A04Rik	Klrb1
OMIM	602890	N/A	N/A
GeneCards	KLRB1	N/A	N/A
Beta Cell Genomics	DT.308363	DT.55111652	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
MGI	N/A	MGI:96877	N/A
WikiGenes	3820	100043861	689817

Relevant resources: