IL10

  Summary from T1DBase   Top   Help
Gene Description:   interleukin 10
Synonyms:   CSIF, Il-10, IL-10, IL10A, IL10, MGC126451, TGIF, IL10X, MGC126450, Il10
Orthologs:   Human IL10 (protein-coding), Mouse Il10 (protein-coding), Rat Il10 (protein-coding)
 
expander Sources
  Regions of Interest Overlapping this feature from T1DBase   Top   Help
Regions Overlapping this Feature:  Human: 1 Mouse: 3 Rat: 1
expander Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Region Species Chromosomal Location Mb Number of genes Marker
1q32.1 Human chr1:206802440..207049831 0.25 30 rs3024505
expander Linkage Regions: Available
expander Other Regions: Available
  Gene Overview from T1DBase   Top   Help
expander (Human) GRCh37 - chr1:206940947..206946034 (59 kb)  View in Genome Browser
expander (Mouse) NCBIM37 - chr1:132916422..132921551 (5.13 kb)  View in Genome Browser
expander (Rat) RGSC3.4 - chr13:43953859..43958331 (4.47 kb)  View in Genome Browser
  Beta Cell Gene Atlas from T1DBase   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
Human Mouse Rat
ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  Tissue Expression   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
/expression/atlas-PB_CD14+_Monocytes.png /expression/atlas-PB_CD56+_NK_Cells.png /expression/atlas-PB_CD19-_B_Cells.png /expression/atlas-PB_CD4+_T_Cells.png /expression/atlas-PB_CD8+_T_Cells.png /expression/atlas-PB_BDCA4+_Dendritic_Cells.png /expression/atlas-721_B_Lymphoblasts.png /expression/atlas-Lymph_Node.png /expression/atlas-Thymus.png /expression/atlas-Salivary_Gland.png /expression/atlas-Bone_Marrow.png /expression/atlas-BM_CD34+.png /expression/atlas-Heart.png /expression/atlas-Skeletal_Muscle.png /expression/atlas-Kidney.png /expression/atlas-Liver.png /expression/atlas-Lung.png /expression/atlas-Pancreas.png /expression/atlas-Pancreatic_Islets.png /expression/atlas-Trachea.png /expression/atlas-Pituitary.png /expression/atlas-Thyroid.png /expression/atlas-Amygdala.png /expression/atlas-Caudate_Nucleus.png /expression/atlas-Cerebellum.png /expression/atlas-Hypothalamus.png /expression/atlas-Spinal_cord.png /expression/atlas-Thalamus.png /expression/atlas-Skin.png /expression/atlas-Ovary.png /expression/atlas-Placenta.png /expression/atlas-Prostate.png /expression/atlas-Testis.png /expression/atlas-Uterus.png
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  HaemAtlas Expression   Top   Help
Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.
CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56
Expression Pattern Not Detected Not Detected Not Detected Not Detected Not Detected Not Detected Not Detected Not Detected HaemAtlasProfile
expander Expression Legend
  Interactions from T1DBase   Top   Help
expander Interactions Table for IL10:
  Cross-Reference to Pathways and GO Terms   Top   Help
expander View all
expander KEGG Network: 16
expander Biocarta: 5
Reactome: None available
expander NCI-Nature Pathway Interaction Database: 3
expander Gene Ontology: 41
  Publications   Top   Help
expander Type 1 Diabetes Publications: 46
expander Publications: 2772
  Model Organism Phenotype Links   Top   Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
Organism Phenotype Resources
Mouse MGI:96537 IKMC
  External Links   Top   Help
  Human Mouse Rat
Entrez Gene 3586 16153 25325
EnsEMBL Gene(s) ENSG00000136634 ENSMUSG00000016529 ENSRNOG00000004647
Unigene Hs.193717 Mm.874 Rn.9868
Homologene IL10 Il10 Il10
OMIM 124092 N/A N/A
GeneCards IL10 N/A N/A
Beta Cell Genomics DT.207856 DT.40185436 N/A
Reactome N/A N/A N/A
Plasma Peptide Atlas N/A N/A N/A
MGI N/A MGI:96537 N/A
WikiGenes 3586 16153 25325
  External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network   Top   Help
dkCOIN_click Relevant resources:
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