FAS

Summary Top Help

Gene Description:

Fas (TNF receptor superfamily, member 6); Fas (TNF receptor superfamily member 6)

Synonyms:

CD95, APT1, FASTM, FAS1, lpr, AI196731, APO-1, ALPS1A, APO1, Fas, TNFR6, FAS, TNFRSF6, Tnfrsf6

Orthologs:

Human FAS (protein-coding), Mouse Fas (protein-coding), Rat Fas (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr10:90729553..90775542 (45.99 kb) View in Genome Browser

(Mouse) NCBIM37 - chr19:34365149..34402260 (37.11 kb) View in Genome Browser

(Rat) RGSC3.4 - chr1:238259200..238274745 (15.54 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for FAS:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for FAS:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 15

Biocarta: 10

Reactome: 6

NCI-Nature Pathway Interaction Database: 5

Gene Ontology: 65

Publications from PubMed Top Help

Type 1 Diabetes Publications: 56

In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18.
Wen L, Green EA, Stratmann T, Panosa A, Gomis R, Eynon EE, Flavell RA, Mezquita JA, Mora C
Eur J Immunol. 2011
PubMed ID: 21469125
Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species.
Affourtit C, Jastroch M, Brand MD
Free Radic Biol Med. 2011
PubMed ID: 21172424
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.
Ferreira RC, Pan-Hammarström Q, Graham RR, Gateva V, Fontán G, Lee AT, Ortmann W, Urcelay E, Fernández-Arquero M, Núñez C, Jorgensen G, Ludviksson BR, Koskinen S, Haimila K, Clark HF, Klareskog L, Gregersen PK, Behrens TW, Hammarström L
Nat Genet. 2010
PubMed ID: 20694011
Non-viral systemic delivery of Fas siRNA suppresses cyclophosphamide-induced diabetes in NOD mice.
Jeong JH, Kim SH, Lee M, Kim WJ, Park TG, Ko KS, Kim SW
J Control Release. 2009
PubMed ID: 20004692
Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
McKenzie MD, Jamieson E, Jansen ES, Scott CL, Huang DC, Bouillet P, Allison J, Kay TW, Strasser A, Thomas HE
Diabetes. 2009
PubMed ID: 19959756
Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion.
Choi D, Radziszewska A, Schroer SA, Liadis N, Liu Y, Zhang Y, Lam PP, Sheu L, Hao Z, Gaisano HY, Woo M
Am J Physiol Endocrinol Metab. 2009
PubMed ID: 19755672
Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes.
Ares-Carrasco S, Picatoste B, Benito-Martín A, Zubiri I, Sanz AB, Sanchez-Miño MD, Ortiz A, Egido J, Tuñón J, Lorenzo O
Am J Physiol Heart Circ Physiol. 2009
PubMed ID: 19820199
XIAP discriminates between type I and type II FAS-induced apoptosis.
Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T
Nature. 2009
PubMed ID: 19626005
Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes.
Niewczas MA, Ficociello LH, Johnson AC, Walker W, Rosolowsky ET, Roshan B, Warram JH, Krolewski AS
Clin J Am Soc Nephrol. 2009
PubMed ID: 19073786
Insulitis in human type 1 diabetes.
Hanafusa T, Imagawa A
Ann N Y Acad Sci. 2008
PubMed ID: 19120316
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.
Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ
J Clin Invest. 2008
PubMed ID: 18776938
Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.
Waid DM, Vaitaitis GM, Pennock ND, Wagner DH
J Leukoc Biol. 2008
PubMed ID: 18469093
Decreased Fetal Size is Associated with Beta Cell Hyperfunction in Early Life and Failure with Age.
Chakravarthy MV, Zhu Y, Wice MB, Coleman T, Pappan KL, Marshall CA, McDaniel ML, Semenkovich CF
Diabetes. 2008
PubMed ID: 18591393
The apoptotic pathway contributing to the deletion of naive CD8 T cells during the induction of peripheral tolerance to a cross-presented self-antigen.
Redmond WL, Wei CH, Kreuwel HT, Sherman LA
J Immunol. 2008
PubMed ID: 18390708
The Fas pathway is involved in pancreatic beta cell secretory function.
Schumann DM, Maedler K, Franklin I, Konrad D, Størling J, Böni-Schnetzler M, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Mandrup-Poulsen T, Wollheim CB, Donath MY
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17299038
Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1.
Maedler K, Schumann DM, Schulthess F, Oberholzer J, Bosco D, Berney T, Donath MY
Diabetes. 2006
PubMed ID: 16936193
Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways.
Dudek NL, Thomas HE, Mariana L, Sutherland RM, Allison J, Estella E, Angstetra E, Trapani JA, Santamaria P, Lew AM, Kay TW
Diabetes. 2006
PubMed ID: 16936188
Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance.
Nolsøe RL, Hamid YH, Pociot F, Paulsen S, Andersen KM, Borch-Johnsen K, Drivsholm T, Hansen T, Pedersen O, Mandrup-Poulsen T
Genes Immun. 2006
PubMed ID: 16691186
Perforin and Fas induced by IFNgamma and TNFalpha mediate beta cell death by OT-I CTL.
McKenzie MD, Dudek NL, Mariana L, Chong MM, Trapani JA, Kay TW, Thomas HE
Int Immunol. 2006
PubMed ID: 16574667
Efficient delivery of siRNA into cytokine-stimulated insulinoma cells silences Fas expression and inhibits Fas-mediated apoptosis.
Burkhardt BR, Lyle R, Qian K, Arnold AS, Cheng H, Atkinson MA, Zhang YC
FEBS Lett. 2006
PubMed ID: 16412430
Abnormal regulation of the cytoskeletal regulator Rho typifies macrophages of the major murine models of spontaneous autoimmunity.
Fan H, Patel VA, Longacre A, Levine JS
J Leukoc Biol. 2006
PubMed ID: 16244106
Distinct effector mechanisms in the development of autoimmune neuropathy versus diabetes in nonobese diabetic mice.
Bour-Jordan H, Thompson HL, Bluestone JA
J Immunol. 2005
PubMed ID: 16237054
Transgenic expression of dominant-negative Fas-associated death domain protein in beta cells protects against Fas ligand-induced apoptosis and reduces spontaneous diabetes in nonobese diabetic mice.
Allison J, Thomas HE, Catterall T, Kay TW, Strasser A
J Immunol. 2005
PubMed ID: 15972661
The role of impaired insulin/IGF action in primary diabetic encephalopathy.
Li ZG, Zhang W, Sima AA
Brain Res. 2005
PubMed ID: 15777748
Impaired recall of CD8 memory T cells in immunologically privileged tissue.
Dai Z, Nasr IW, Reel M, Deng S, Diggs L, Larsen CP, Rothstein DM, Lakkis FG
J Immunol. 2005
PubMed ID: 15661869
Thyrotropin releasing hormone (TRH) affects gene expression in pancreatic beta-cells.
Luo L, Yano N
Endocr Res. 2005
PubMed ID: 16392621
Fas deficiency prevents type 1 diabetes by inducing hyporesponsiveness in islet beta-cell-reactive T-cells.
Vence L, Benoist C, Mathis D
Diabetes. 2004
PubMed ID: 15504959
Fas ligand down-regulates cytokine-induced Fas receptor expression on insulinoma (NIT-1), but not islet cells, from autoimmune nonobese diabetic mice.
Augstein P, Heinke P, Salzsieder E, Berg S, Rettig R, Salzsieder C, Harrison LC
Endocrinology. 2004
PubMed ID: 15033908
Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice.
Robey IF, Peterson M, Horwitz MS, Kono DH, Stratmann T, Theofilopoulos AN, Sarvetnick N, Teyton L, Feeney AJ
J Immunol. 2004
PubMed ID: 15034081
Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes.
Apostolou I, Hao Z, Rajewsky K, von Boehmer H
J Exp Med. 2003
PubMed ID: 14530378
Fas is detectable on beta cells in accelerated, but not spontaneous, diabetes in nonobese diabetic mice.
Darwiche R, Chong MM, Santamaria P, Thomas HE, Kay TW
J Immunol. 2003
PubMed ID: 12794162
Surface and intracellular Fas expression associated with cytokine-induced apoptosis in rodent islet and insulinoma cells.
Augstein P, Wachlin G, Berg S, Bahr J, Salzsieder C, Hehmke B, Heinke P, Salzsieder E
J Mol Endocrinol. 2003
PubMed ID: 12683940
Contribution of Fas to diabetes development.
Savinov AY, Tcherepanov A, Green EA, Flavell RA, Chervonsky AV
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12525697
FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication.
Maedler K, Fontana A, Ris F, Sergeev P, Toso C, Oberholzer J, Lehmann R, Bachmann F, Tasinato A, Spinas GA, Halban PA, Donath MY
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12060768
The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis.
Straus SE, Jaffe ES, Puck JM, Dale JK, Elkon KB, Rösen-Wolff A, Peters AM, Sneller MC, Hallahan CW, Wang J, Fischer RE, Jackson CM, Lin AY, Bäumler C, Siegert E, Marx A, Vaishnaw AK, Grodzicky T, Fleisher TA, Lenardo MJ
Blood. 2001
PubMed ID: 11418480
Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.
Balasa B, Van Gunst K, Jung N, Balakrishna D, Santamaria P, Hanafusa T, Itoh N, Sarvetnick N
J Immunol. 2000
PubMed ID: 10946317
Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved.
Kim S, Kim KA, Hwang DY, Lee TH, Kayagaki N, Yagita H, Lee MS
J Immunol. 2000
PubMed ID: 10706679
Significant role for Fas in the pathogenesis of autoimmune diabetes.
Su X, Hu Q, Kristan JM, Costa C, Shen Y, Gero D, Matis LA, Wang Y
J Immunol. 2000
PubMed ID: 10679090
Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus.
Kreuwel HT, Morgan DJ, Krahl T, Ko A, Sarvetnick N, Sherman LA
J Immunol. 1999
PubMed ID: 10510373
Induction of allograft tolerance in the absence of Fas-mediated apoptosis.
Li XC, Li Y, Dodge I, Wells AD, Zheng XX, Turka LA, Strom TB
J Immunol. 1999
PubMed ID: 10452986
Two mechanisms for the non-MHC-linked resistance to spontaneous autoimmunity.
Verdaguer J, Amrani A, Anderson B, Schmidt D, Santamaria P
J Immunol. 1999
PubMed ID: 10202001
Hypogammaglobulinaemia occurs in Fas-deficient MRL-lpr mice following deletion of MHC class II molecules.
Anderson CC, Mukherjee R, Sinclair NR, Jevnikar AM
Clin Exp Immunol. 1997
PubMed ID: 9328125
Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice.
Itoh N, Imagawa A, Hanafusa T, Waguri M, Yamamoto K, Iwahashi H, Moriwaki M, Nakajima H, Miyagawa J, Namba M, Makino S, Nagata S, Kono N, Matsuzawa Y
J Exp Med. 1997
PubMed ID: 9254659
Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction.
Kang SM, Schneider DB, Lin Z, Hanahan D, Dichek DA, Stock PG, Baekkeskov S
Nat Med. 1997
PubMed ID: 9212099
Elevated levels of cysteine protease activity in saliva and salivary glands of the nonobese diabetic (NOD) mouse model for Sjögren syndrome.
Robinson CP, Yamachika S, Alford CE, Cooper C, Pichardo EL, Shah N, Peck AB, Humphreys-Beher MG
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9159148
Islet rejection in perforin-deficient mice: the role of perforin and Fas.
Ahmed KR, Guo TB, Gaal KK
Transplantation. 1997
PubMed ID: 9112346
The role of Fas in autoimmune diabetes.
Chervonsky AV, Wang Y, Wong FS, Visintin I, Flavell RA, Janeway CA, Matis LA
Cell. 1997
PubMed ID: 9094710
Mouse islet cell lysis mediated by interleukin-1-induced Fas.
Yamada K, Takane-Gyotoku N, Yuan X, Ichikawa F, Inada C, Nonaka K
Diabetologia. 1996
PubMed ID: 8932996
Dual T cell receptor alpha chain T cells in autoimmunity.
Elliott JI, Altmann DM
J Exp Med. 1995
PubMed ID: 7561698
T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice.
Hughes DP, Hayday A, Craft JE, Owen MJ, Crispe IN
J Exp Med. 1995
PubMed ID: 7540652
Characterization of intermediate T-cell receptor cells expanding in the liver, thymus and other organs in autoimmune lpr mice: parallel analysis with their normal counterparts.
Iiai T, Kimura M, Kawachi Y, Hirokawa K, Watanabe H, Hatakeyama K, Abo T
Immunology. 1995
PubMed ID: 7790034
Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin.
Mixter PF, Russell JQ, Durie FH, Budd RC
J Immunol. 1995
PubMed ID: 7868883
Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules.
Ohteki T, Iwamoto M, Izui S, MacDonald HR
Eur J Immunol. 1995
PubMed ID: 7531148
Oligoclonality of T cells in salivary glands of autoimmune MRL/lpr mice.
Skarstein K, Holmdahl R, Johannessen AC, Jonsson R
Immunology. 1994
PubMed ID: 8039804
The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally admi
Weinberg JB, Granger DL, Pisetsky DS, Seldin MF, Misukonis MA, Mason SN, Pippen AM, Ruiz P, Wood ER, Gilkeson GS
J Exp Med. 1994
PubMed ID: 7507509
Non-MHC-linked genes in autoimmune diseases.
Garchon HJ
Curr Opin Immunol. 1993
PubMed ID: 8297521

Publications: 1946

Natural killer cells act as rheostats modulating antiviral T cells.
Waggoner SN, Cornberg M, Selin LK, Welsh RM
Nature. 2012
PubMed ID: 22101430
Mice with mutations in Fas and Fas ligand demonstrate increased herpetic stromal keratitis following corneal infection with HSV-1.
Morris JE, Zobell S, Yin XT, Zakeri H, Summers BC, Leib DA, Stuart PM
J Immunol. 2012
PubMed ID: 22156346
A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia.
Sunter NJ, Scott K, Hills R, Grimwade D, Taylor S, Worrillow LJ, Fordham SE, Forster VJ, Jackson G, Bomken S, Jones G, Allan JM
Blood. 2012
PubMed ID: 22084312
Reduced CaM/FLIP binding by a single point mutation in c-FLIP(L) modulates Fas-mediated apoptosis and decreases tumorigenesis.
Jing G, Yuan K, Liang Q, Sun Y, Mao X, McDonald JM, Chen Y
Lab Invest. 2012
PubMed ID: 21912376
PINCH mRNA overexpression in colorectal carcinomas correlated with VEGF and FAS mRNA expression.
Zhang ZY, Tian YF, Wang YY, Zhang LJ, Zhao ZR, Sun XF
Anticancer Res. 2011
PubMed ID: 22199270
Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α.
Liu Y, Wang L, Kikuiri T, Akiyama K, Chen C, Xu X, Yang R, Chen W, Wang S, Shi S
Nat Med. 2011
PubMed ID: 22101767
Cutting edge: Calcium/Calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis.
Ichinose K, Rauen T, Juang YT, Kis-Toth K, Mizui M, Koga T, Tsokos GC
J Immunol. 2011
PubMed ID: 22031763
Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells.
Chen M, Felix K, Wang J
J Immunol. 2011
PubMed ID: 22031758
TNF-α/Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations.
Xiao Y, Li H, Zhang J, Volk A, Zhang S, Wei W, Zhang S, Breslin P, Zhang J
Blood. 2011
PubMed ID: 21989986
Fas/FasL pathway-mediated alveolar macrophage apoptosis involved in human silicosis.
Yao SQ, Rojanasakul LW, Chen ZY, Xu YJ, Bai YP, Chen G, Zhang XY, Zhang CM, Yu YQ, Shen FH, Yuan JX, Chen J, He QC
Apoptosis. 2011
PubMed ID: 21910009
Escherichia coli induces apoptosis in human monocytic U937 cells through the Fas/FasL signaling pathway.
Wang JH, Peng Y, Yang LL, Wang YB, Wu BG, Zhang Y, He P
Mol Cell Biochem. 2011
PubMed ID: 21691772
Bile salts differentially sensitize esophageal squamous cells to CD95 (Fas/Apo-1 receptor) mediated apoptosis.
Naran S, Abrams P, de Oliveira PQ, Hughes SJ
J Surg Res. 2011
PubMed ID: 20934723
CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.
Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P
Proc Natl Acad Sci U S A. 2011
PubMed ID: 22065776
Death receptor 5 signaling promotes hepatocyte lipoapoptosis.
Cazanave SC, Mott JL, Bronk SF, Werneburg NW, Fingas CD, Meng XW, Finnberg N, El-Deiry WS, Kaufmann SH, Gores GJ
J Biol Chem. 2011
PubMed ID: 21941003
A survey of 90 patients with autoimmune lymphoproliferative syndrome related to TNFRSF6 mutation.
Neven B, Magerus-Chatinet A, Florkin B, Gobert D, Lambotte O, De Somer L, Lanzarotti N, Stolzenberg MC, Bader-Meunier B, Aladjidi N, Chantrain C, Bertrand Y, Jeziorski E, Leverger G, Michel G, Suarez F, Oksenhendler E, Hermine O, Blanche S, Picard C, Fischer A, Rieux-Laucat F
Blood. 2011
PubMed ID: 21885602
Mucosal memory CD8⁺ T cells are selected in the periphery by an MHC class I molecule.
Huang Y, Park Y, Wang-Zhu Y, Larange A, Arens R, Bernardo I, Olivares-Villagómez D, Herndler-Brandstetter D, Abraham N, Grubeck-Loebenstein B, Schoenberger SP, Van Kaer L, Kronenberg M, Teitell MA, Cheroutre H
Nat Immunol. 2011
PubMed ID: 21964609
Over-expressed Fas improves the apoptosis of malignant T-cells in vitro and vivo.
Li L, Zhang R, Chen Z, Xue S, Wang X, Ruan C
Mol Biol Rep. 2011
PubMed ID: 21390503
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation.
Bonnet MC, Preukschat D, Welz PS, van Loo G, Ermolaeva MA, Bloch W, Haase I, Pasparakis M
Immunity. 2011
PubMed ID: 22000287
Organization and dynamics of Fas transmembrane domain in raft membranes and modulation by ceramide.
Castro BM, de Almeida RF, Goormaghtigh E, Fedorov A, Prieto M
Biophys J. 2011
PubMed ID: 21961589
An acquired defect in IgG-dependent phagocytosis explains the impairment in antibody-mediated cellular depletion in Lupus.
Ahuja A, Teichmann LL, Wang H, Dunn R, Kehry MR, Shlomchik MJ
J Immunol. 2011
PubMed ID: 21873531
Pathogenic role of B cells in the development of diffuse alveolar hemorrhage induced by pristane.
Barker TT, Lee PY, Kelly-Scumpia KM, Weinstein JS, Nacionales DC, Kumagai Y, Akira S, Croker BP, Sobel ES, Reeves WH, Satoh M
Lab Invest. 2011
PubMed ID: 21808234
Overexpression of gastrokine 1 in gastric cancer cells induces Fas-mediated apoptosis.
Rippa E, La Monica G, Allocca R, Romano MF, De Palma M, Arcari P
J Cell Physiol. 2011
PubMed ID: 21792914
Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice.
van den Berg E, van Woensel JB, Bos AP, Bem RA, Altemeier WA, Gill SE, Martin TR, Matute-Bello G
Am J Physiol Lung Cell Mol Physiol. 2011
PubMed ID: 21743025
Interplay between Ret and Fap-1 regulates CD95-mediated apoptosis in medullary thyroid cancer cells.
Nicolini V, Cassinelli G, Cuccuru G, Bongarzone I, Petrangolini G, Tortoreto M, Mondellini P, Casalini P, Favini E, Zaffaroni N, Zunino F, Lanzi C
Biochem Pharmacol. 2011
PubMed ID: 21741956
Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3.
Wang HQ, Yu XD, Liu ZH, Cheng X, Samartzis D, Jia LT, Wu SX, Huang J, Chen J, Luo ZJ
J Pathol. 2011
PubMed ID: 21706480
Attenuated neurological deficit, cell death and lesion volume in Fas-mutant mice is associated with altered neuroinflammation following traumatic brain injury.
Ziebell JM, Bye N, Semple BD, Kossmann T, Morganti-Kossmann MC
Brain Res. 2011
PubMed ID: 21871613
Activated protein C attenuates systemic lupus erythematosus and lupus nephritis in MRL-Fas(lpr) mice.
Lichtnekert J, Rupanagudi KV, Kulkarni OP, Darisipudi MN, Allam R, Anders HJ
J Immunol. 2011
PubMed ID: 21849682
Murine antithymocyte globulin T-cell depletion is mediated predominantly by macrophages, but the Fas/FasL pathway selectively targets regulatory T cells.
Neff KS, Richards SM, Williams JM, Garman RD, Ruzek MC
Transplantation. 2011
PubMed ID: 21804441
PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo.
Tao RH, Berkova Z, Wise JF, Rezaeian AH, Daniluk U, Ao X, Hawke DH, Karp JE, Lin HK, Molldrem JJ, Samaniego F
Blood. 2011
PubMed ID: 21803845
Association of FAS and FAS ligand polymorphisms with the susceptibility and severity of lumbar disc degeneration in Chinese Han population.
Zhu GB, Jiang XR, Xia CL, Sun YJ, Zeng QS, Wu XM, Li XC
Biomarkers. 2011
PubMed ID: 21806408
Lipid rafts and Fas/CD95 signaling in cancer chemotherapy.
Gajate C, Mollinedo F
Recent Pat Anticancer Drug Discov. 2011
PubMed ID: 21762074
The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion.
Steller EJ, Ritsma L, Raats DA, Hoogwater FJ, Emmink BL, Govaert KM, Laoukili J, Rinkes IH, van Rheenen J, Kranenburg O
EMBO Rep. 2011
PubMed ID: 21760611
The prognostic impact of soluble apoptosis-stimulating fragment on mortality in patients with carotid atherosclerosis.
Hoke M, Schillinger M, Zorn G, Wonnerth A, Amighi J, Mlekusch W, Speidl W, Maurer G, Koppensteiner R, Minar E, Wojta J, Niessner A
Stroke. 2011
PubMed ID: 21757675
Fluorofenidone inhibits Ang II-induced apoptosis of renal tubular cells through blockage of the Fas/FasL pathway.
Ning WB, Hu GY, Peng ZZ, Wang L, Wang W, Chen JY, Zheng X, Li J, Tao LJ
Int Immunopharmacol. 2011
PubMed ID: 21586345
Fas activation in alveolar epithelial cells induces KC (CXCL1) release by a MyD88-dependent mechanism.
Farnand AW, Eastman AJ, Herrero R, Hanson JF, Mongovin S, Altemeier WA, Matute-Bello G
Am J Respir Cell Mol Biol. 2011
PubMed ID: 21257927
Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1.
Croker BA, O'Donnell JA, Nowell CJ, Metcalf D, Dewson G, Campbell KJ, Rogers KL, Hu Y, Smyth GK, Zhang JG, White M, Lackovic K, Cengia LH, O'Reilly LA, Bouillet P, Cory S, Strasser A, Roberts AW
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21768356
MHC class II upregulation and colocalization with Fas in experimental models of immune-mediated bone marrow failure.
Erie AJ, Samsel L, Takaku T, Desierto MJ, Keyvanfar K, McCoy JP, Young NS, Chen J
Exp Hematol. 2011
PubMed ID: 21635935
Tgf-beta-mediated FasL-Fas-Caspase pathway is crucial during palatogenesis.
Huang X, Yokota T, Iwata J, Chai Y
J Dent Res. 2011
PubMed ID: 21593251
Actin-independent exclusion of CD95 by PI3K/AKT signalling: implications for apoptosis.
Pizon M, Rampanarivo H, Tauzin S, Chaigne-Delalande B, Daburon S, Castroviejo M, Moreau P, Moreau JF, Legembre P
Eur J Immunol. 2011
PubMed ID: 21557211
Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways.
Mou H, Zheng Y, Zhao P, Bao H, Fang W, Xu N
Toxicol In Vitro. 2011
PubMed ID: 21466843
Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK).
Yuan K, Jing G, Chen J, Liu H, Zhang K, Li Y, Wu H, McDonald JM, Chen Y
J Biol Chem. 2011
PubMed ID: 21613217
Fas receptor (CD95) & Fas ligand (CD178) expression in patients with tobacco-related intraoral squamous cell carcinoma.
Das SN, Khare P, Singh MK, Sharma SC
Indian J Med Res. 2011
PubMed ID: 21808135
Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of prostate cancer in a Chinese population.
Shao P, Ding Q, Qin C, Wang M, Tang J, Zhu J, Chen J, Cao Q, Li J, Xu B, Zhang Z, Zhang W, Yin C
Prostate. 2011
PubMed ID: 21557277
Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Swindall AF, Bellis SL
J Biol Chem. 2011
PubMed ID: 21550977
Association of FAS, a TNF-α receptor gene, with treatment resistant schizophrenia.
Jia P, Jayathilake K, Zhao Z, Meltzer HY
Schizophr Res. 2011
PubMed ID: 21549565
Matrix metalloproteinases and soluble Fas/FasL system as novel regulators of apoptosis in children and young adults on chronic dialysis.
Musiał K, Zwolińska D
Apoptosis. 2011
PubMed ID: 21516345
Death receptors mediate the adverse effects of febrile-range hyperthermia on the outcome of lipopolysaccharide-induced lung injury.
Lipke AB, Matute-Bello G, Herrero R, Wong VA, Mongovin SM, Martin TR
Am J Physiol Lung Cell Mol Physiol. 2011
PubMed ID: 21515659
Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.
Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N
Hepatology. 2011
PubMed ID: 21425311
Does calcium contribute to the CD95 signaling pathway?
Vacher P, Khadra N, Vacher AM, Charles E, Bresson-Bepoldin L, Legembre P
Anticancer Drugs. 2011
PubMed ID: 21317766
Inflammatory cytokines determine the susceptibility of human CD8 T cells to Fas-mediated activation-induced cell death through modulation of FasL and c-FLIP(S) expression.
von Rossum A, Krall R, Escalante NK, Choy JC
J Biol Chem. 2011
PubMed ID: 21518761
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
[Mechanism of Fas/FasL signal transduction pathway in K562 cell apoptosis induced by diallyl disulfide].
Yin XC, Peng YH, Xiao ZX
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2011
PubMed ID: 21729539
Flow cytometric analysis of STAT5 phosphorylation and CD95 expression in CD4+ T lymphocytes treated with recombinant human erythropoietin.
Lisowska KA, Dębska-Ślizień A, Jasiulewicz A, Jóźwik A, Rutkowski B, Bryl E, Witkowski JM
J Recept Signal Transduct Res. 2011
PubMed ID: 21619451
Hematopoietic Fas deficiency does not affect experimental atherosclerotic lesion formation despite inducing a proatherogenic state.
de Claro RA, Zhu X, Tang J, Morgan-Stevenson V, Schwartz BR, Iwata A, Liles WC, Raines EW, Harlan JM
Am J Pathol. 2011
PubMed ID: 21550016
B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus.
Jiang C, Loo WM, Greenley EJ, Tung KS, Erickson LD
J Immunol. 2011
PubMed ID: 21536804
Pivotal Role of Antibody and Subsidiary Contribution of CD8+ T Cells to Recovery from Infection in a Murine Model of Japanese Encephalitis.
Larena M, Regner M, Lee E, Lobigs M
J Virol. 2011
PubMed ID: 21450826
Autophagy activation in the injured photoreceptor inhibits fas-mediated apoptosis.
Besirli CG, Chinskey ND, Zheng QD, Zacks DN
Invest Ophthalmol Vis Sci. 2011
PubMed ID: 21421874
S-nitrosylation of the death receptor fas promotes fas ligand-mediated apoptosis in cancer cells.
Leon-Bollotte L, Subramaniam S, Cauvard O, Plenchette-Colas S, Paul C, Godard C, Martinez-Ruiz A, Legembre P, Jeannin JF, Bettaieb A
Gastroenterology. 2011
PubMed ID: 21354149
An apoptosis panel for nonalcoholic steatohepatitis diagnosis.
Tamimi TI, Elgouhari HM, Alkhouri N, Yerian LM, Berk MP, Lopez R, Schauer PR, Zein NN, Feldstein AE
J Hepatol. 2011
PubMed ID: 21145805
Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis.
Toivonen HT, Meinander A, Asaoka T, Westerlund M, Pettersson F, Mikhailov A, Eriksson JE, Saxén H
J Biol Chem. 2011
PubMed ID: 21324892
Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL.
Sinha P, Chornoguz O, Clements VK, Artemenko KA, Zubarev RA, Ostrand-Rosenberg S
Blood. 2011
PubMed ID: 21450901
FAS haploinsufficiency is a common disease mechanism in the human autoimmune lymphoproliferative syndrome.
Kuehn HS, Caminha I, Niemela JE, Rao VK, Davis J, Fleisher TA, Oliveira JB
J Immunol. 2011
PubMed ID: 21490157
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis.
Zhang M, Lee SJ, An C, Xu JF, Joshi B, Nabi IR, Choi AM, Jin Y
Free Radic Biol Med. 2011
PubMed ID: 21382479
A let-7/Fas double-negative feedback loop regulates human colon carcinoma cells sensitivity to Fas-related apoptosis.
Geng L, Zhu B, Dai BH, Sui CJ, Xu F, Kan T, Shen WF, Yang JM
Biochem Biophys Res Commun. 2011
PubMed ID: 21530489
Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex.
Kavuri SM, Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D, Gollnick H, Neumann M, Wajant H, Leverkus M
J Biol Chem. 2011
PubMed ID: 21454681
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C.
Siggs OM, Schnabl B, Webb B, Beutler B
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21518881
A -436C>A polymorphism in the human FAS gene promoter associated with severe childhood malaria.
Schuldt K, Kretz CC, Timmann C, Sievertsen J, Ehmen C, Esser C, Loag W, Ansong D, Dering C, Evans J, Ziegler A, May J, Krammer PH, Agbenyega T, Horstmann RD
PLoS Genet. 2011
PubMed ID: 21625619
Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas-independent liver injury in MRL-lpr/lpr mice.
Oya Y, Watanabe N, Kobayashi Y, Owada T, Oki M, Ikeda K, Suto A, Kagami S, Hirose K, Kishimoto T, Nakajima H
Int Immunol. 2011
PubMed ID: 21521881
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow.
Siggs OM, Arnold CN, Huber C, Pirie E, Xia Y, Lin P, Nemazee D, Beutler B
Nat Immunol. 2011
PubMed ID: 21423172
High soluble Fas and soluble Fas Ligand serum levels before stent implantation are protective against restenosis.
Katsaros KM, Wiesbauer F, Speidl WS, Kastl SP, Huber K, Zorn G, Niessner A, Glogar D, Maurer G, Wojta J
Thromb Haemost. 2011
PubMed ID: 21359408
Genetic polymorphisms of TP53 and FAS promoter modulate the progression of coronary artery disease after coronary artery bypass grafting: a gender-specific view.
Beiras-Fernandez A, Angele MK, Koutang C, Lohse P, Reichart B, Lohse P, Eifert S
Inflamm Res. 2011
PubMed ID: 21286777
Fas-FasL system in molar pregnancy.
Soni S, Rath G, Prasad CP, Salhan S, Jain AK, Saxena S
Am J Reprod Immunol. 2011
PubMed ID: 21087335
Dendritic cells and CD28 costimulation are required to sustain virus-specific CD8+ T cell responses during the effector phase in vivo.
Dolfi DV, Duttagupta PA, Boesteanu AC, Mueller YM, Oliai CH, Borowski AB, Katsikis PD
J Immunol. 2011
PubMed ID: 21389258
Structural alterations of the FAS gene in cutaneous T-cell lymphoma (CTCL).
Wu J, Siddiqui J, Nihal M, Vonderheid EC, Wood GS
Arch Biochem Biophys. 2011
PubMed ID: 21036138
Overexpression of IL-32alpha increases natural killer cell-mediated killing through up-regulation of Fas and UL16-binding protein 2 (ULBP2) expression in human chronic myeloid leukemia cells.
Cheon S, Lee JH, Park S, Bang SI, Lee WJ, Yoon DY, Yoon SS, Kim T, Min H, Cho BJ, Lee HJ, Lee KW, Jeong SH, Park H, Cho D
J Biol Chem. 2011
PubMed ID: 21321117
Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma.
Wu J, Wood GS
Arch Dermatol. 2011
PubMed ID: 21173302
FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.
Bivona TG, Hieronymus H, Parker J, Chang K, Taron M, Rosell R, Moonsamy P, Dahlman K, Miller VA, Costa C, Hannon G, Sawyers CL
Nature. 2011
PubMed ID: 21430781
STAT3 enhances intracellular Fas-mediated apoptotic signals in HHUA human endometrial epithelial cells.
Tanaka T, Bai T, Utsunomiya H, Fukumoto T, Yukawa K
Mol Med Report. 2011
PubMed ID: 21468569
Influence of FAS on murine mast cell maturation.
Berent-Maoz B, Gur C, Vita F, Soranzo MR, Zabucchi G, Levi-Schaffer F
Ann Allergy Asthma Immunol. 2011
PubMed ID: 21354026
Strict 3' splice site sequence requirements for U2 snRNP recruitment after U2AF binding underlie a genetic defect leading to autoimmune disease.
Corrionero A, Raker VA, Izquierdo JM, Valcárcel J
RNA. 2011
PubMed ID: 21233219
Increased plasma levels of adipokines and inflammatory markers in older women with persistent HPV infection.
Baker R, Dauner JG, Rodriguez AC, Williams MC, Kemp TJ, Hildesheim A, Pinto LA
Cytokine. 2011
PubMed ID: 21167737
Expression and prognostic relevance of the death receptor CD95 (Fas/APO1) in renal cell carcinomas.
Macher-Goeppinger S, Bermejo JL, Wagener N, Hohenfellner M, Haferkamp A, Schirmacher P, Roth W
Cancer Lett. 2011
PubMed ID: 21196076
Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts.
Fortner KA, Lees RK, MacDonald HR, Budd RC
Int Immunol. 2011
PubMed ID: 21266499
Platelets prevent acute hepatitis induced by anti-fas antibody.
Hisakura K, Murata S, Takahashi K, Matsuo R, Pak S, Ikeda N, Kawasaki T, Kohno K, Myronovych A, Nakano Y, Ikeda O, Watanabe M, Ohkohchi N
J Gastroenterol Hepatol. 2011
PubMed ID: 21261726
A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface.
Shukla S, Fujita K, Xiao Q, Liao Z, Garfield S, Srinivasula SM
Apoptosis. 2011
PubMed ID: 21107705
Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice.
Khuman J, Meehan WP, Zhu X, Qiu J, Hoffmann U, Zhang J, Giovannone E, Lo EH, Whalen MJ
J Cereb Blood Flow Metab. 2011
PubMed ID: 20940727
De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.
Wei X, Schneider JG, Shenouda SM, Lee A, Towler DA, Chakravarthy MV, Vita JA, Semenkovich CF
J Biol Chem. 2011
PubMed ID: 21098489
Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision.
Hale JS, Nelson LT, Simmons KB, Fink PJ
J Immunol. 2011
PubMed ID: 21148799
Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.
Lückerath K, Kirkin V, Melzer IM, Thalheimer FB, Siele D, Milani W, Adler T, Aguilar-Pimentel A, Horsch M, Michel G, Beckers J, Busch DH, Ollert M, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Staal FJ, Rajalingam K, Hueber AO, Strobl LJ, Zimber-Strobl U, Zörnig M
Blood. 2011
PubMed ID: 20971954
Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions and gastric cancer in Caucasians.
Kupcinskas J, Wex T, Bornschein J, Selgrad M, Leja M, Juozaityte E, Kiudelis G, Jonaitis L, Malfertheiner P
BMC Med Genet. 2011
PubMed ID: 21864388
Defects in apoptosis increase memory CD8+ T cells following infection of Bim-/-Faslpr/lpr mice.
Weant AE, Michalek RD, Crump KE, Liu C, Konopitski AP, Grayson JM
Cell Immunol. 2011
PubMed ID: 21839428
Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response.
Koulnis M, Liu Y, Hallstrom K, Socolovsky M
PLoS One. 2011
PubMed ID: 21760888
Stimulation of Fas (CD95) induces production of pro-inflammatory mediators through ERK/JNK-dependent activation of NF-κB in THP-1 cells.
Lee SM, Kim EJ, Suk K, Lee WH
Cell Immunol. 2011
PubMed ID: 21752354
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus.
Lech M, Römmele C, Kulkarni OP, Susanti HE, Migliorini A, Garlanda C, Mantovani A, Anders HJ
PLoS One. 2011
PubMed ID: 21637713
Correlation between Fas and FasL proteins expression in normal gastric mucosa and gastric cancer.
Gryko M, Guzińska-Ustymowicz K, Pryczynicz A, Cepowicz D, Kukliński A, Czyżewska J, Kemona A, Kędra B
Folia Histochem Cytobiol. 2011
PubMed ID: 21526501
Hepatitis C virus protects human B lymphocytes from Fas-mediated apoptosis via E2-CD81 engagement.
Chen Z, Zhu Y, Ren Y, Tong Y, Hua X, Zhu F, Huang L, Liu Y, Luo Y, Lu W, Zhao P, Qi Z
PLoS One. 2011
PubMed ID: 21526201
[Regulation of death receptor-induced apoptosis induced via CD95/FAS and other death receptors].
Lavrik IN
Mol Biol (Mosk). 2011
PubMed ID: 21485506
Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death.
Gregory MS, Hackett CG, Abernathy EF, Lee KS, Saff RR, Hohlbaum AM, Moody KS, Hobson MW, Jones A, Kolovou P, Karray S, Giani A, John SW, Chen DF, Marshak-Rothstein A, Ksander BR
PLoS One. 2011
PubMed ID: 21479271
Role of Fas/FasL in regulation of inflammation in vaginal tissue during HSV-2 infection.
Krzyzowska M, Shestakov A, Eriksson K, Chiodi F
Cell Death Dis. 2011
PubMed ID: 21412278
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Elevated serum-soluble Fas in preeclampsia: correlation with clinical, laboratory, and Doppler parameters.
El-Sherbiny W, Soliman A, El-Mazny A
Hypertens Pregnancy. 2011
PubMed ID: 21250890
Enhanced contact allergen- and UVB-induced keratinocyte apoptosis in the absence of CD95/Fas/Apo-1.
Hedrych-Ozimina A, Behrendt K, Hao Z, Pofahl R, Ussath D, Knaup R, Krieg T, Haase I
Cell Death Differ. 2011
PubMed ID: 20689557
Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.
Kinjyo I, Gordon SM, Intlekofer AM, Dowdell K, Mooney EC, Caricchio R, Grupp SA, Teachey DT, Rao VK, Lindsten T, Reiner SL
J Immunol. 2010
PubMed ID: 21076068
Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage.
Teichmann LL, Ols ML, Kashgarian M, Reizis B, Kaplan DH, Shlomchik MJ
Immunity. 2010
PubMed ID: 21167752
Whole-exome-sequencing-based discovery of human FADD deficiency.
Bolze A, Byun M, McDonald D, Morgan NV, Abhyankar A, Premkumar L, Puel A, Bacon CM, Rieux-Laucat F, Pang K, Britland A, Abel L, Cant A, Maher ER, Riedl SJ, Hambleton S, Casanova JL
Am J Hum Genet. 2010
PubMed ID: 21109225
Investigation of genetic susceptibility factors for human longevity - A targeted nonsynonymous SNP study.
Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A
Mutat Res. 2010
PubMed ID: 20800603
The Fas-mediated apoptotic pathway in cardiac myxoma.
Liu CC, Jung SM, Orlandi A, Yeh TS, Lin YS, Shiu TF, Wu HH, Chu JJ, Lin PJ, Chu PH
Int J Surg Pathol. 2010
PubMed ID: 21081533
A Fas gene polymorphism influences herpes simplex virus type 2 infection in South African women.
Chatterjee K, Dandara C, Gyllensten U, van der Merwe L, Galal U, Hoffman M, Williamson AL
J Med Virol. 2010
PubMed ID: 20981796
Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility.
Villa-Morales M, González-Gugel E, Shahbazi MN, Santos J, Fernández-Piqueras J
Carcinogenesis. 2010
PubMed ID: 20889682
The adaptor protein TRIP6 antagonizes Fas-induced apoptosis but promotes its effect on cell migration.
Lai YJ, Lin VT, Zheng Y, Benveniste EN, Lin FT
Mol Cell Biol. 2010
PubMed ID: 20876301
CD95 is a key mediator of invasion and accelerated outgrowth of mouse colorectal liver metastases following radiofrequency ablation.
Nijkamp MW, Hoogwater FJ, Steller EJ, Westendorp BF, van der Meulen TA, Leenders MW, Borel Rinkes IH, Kranenburg O
J Hepatol. 2010
PubMed ID: 20832890
MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.
Zhang X, Yang H, Lee JJ, Kim E, Lippman SM, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X
Carcinogenesis. 2010
PubMed ID: 20819778
CD95 is not functional in human erythrocytes.
Sagan D, Jermnim N, Tangvarasittichai O
Int J Lab Hematol. 2010
PubMed ID: 20682001
Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science.
Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, Pulley JM, Basford MA, Masys DR, Haines JL, Roden DM
Circulation. 2010
PubMed ID: 21041692
Polymorphism in tumor necrosis factor-related apoptosis-inducing ligand receptor 1 is associated with poor viral response to interferon-based hepatitis C virus therapy in HIV/hepatitis C virus-coinfected individuals.
Rizza SA, Cummins NW, Rider DN, Saeed S, Klein MB, Badley AD
AIDS. 2010
PubMed ID: 20802294
Cell-specific regulation of Fas exon 6 splicing mediated by Hu antigen R.
Izquierdo JM
Biochem Biophys Res Commun. 2010
PubMed ID: 20951677
Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Casabonne D, Reina O, Benavente Y, Becker N, Maynadie' M, Foretova L, Cocco P, Gonzalez-Neira A, Nieters A, Boffetta P, Middeldorp JM, de Sanjose S
Haematologica. 2010
PubMed ID: 21048031
Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation.
Fortner KA, Bouillet P, Strasser A, Budd RC
Eur J Immunol. 2010
PubMed ID: 21061436
IL1/IL1 Ra, CTLA-4 and Apo1/Fas genes polymorphisms and susceptibility to IgA nephropathy in Tunisian patients.
Gorgi Y, Sfar I, Goucha R, Aouadi H, Amri M, Makhlouf M, Ben Romdhane T, Cherif M, Jendoubi-Ayed S, Ben Abdallah T, Ayed K
Tunis Med. 2010
PubMed ID: 21049406
The IFNG (IFN-gamma) genotype predicts cytogenetic and molecular response to imatinib therapy in chronic myeloid leukemia.
Kim DH, Kong JH, Byeun JY, Jung CW, Xu W, Liu X, Kamel-Reid S, Kim YK, Kim HJ, Lipton JH
Clin Cancer Res. 2010
PubMed ID: 20959405
The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.
Wang L, Yang JK, Kabaleeswaran V, Rice AJ, Cruz AC, Park AY, Yin Q, Damko E, Jang SB, Raunser S, Robinson CV, Siegel RM, Walz T, Wu H
Nat Struct Mol Biol. 2010
PubMed ID: 20935634
Dendritic cells recruit T cell exosomes via exosomal LFA-1 leading to inhibition of CD8+ CTL responses through downregulation of peptide/MHC class I and Fas ligand-mediated cytotoxicity.
Xie Y, Zhang H, Li W, Deng Y, Munegowda MA, Chibbar R, Qureshi M, Xiang J
J Immunol. 2010
PubMed ID: 20881190
Polymorphisms of death pathway genes FAS and FASL and risk of nasopharyngeal carcinoma.
Cao Y, Miao XP, Huang MY, Deng L, Lin DX, Zeng YX, Shao JY
Mol Carcinog. 2010
PubMed ID: 20842669
Impact of cytokine gene polymorphisms on risk and treatment outcomes of aplastic anemia.
Lee YG, Kim I, Kim JH, Bae JY, Kwon JH, Shin DY, Lee JE, Song EY, Kim HK, Yoon SS, Park SS, Lee DS, Han KS, Park MH, Hong YC, Park S, Kim BK
Ann Hematol. 2010
PubMed ID: 20953611
Solution NMR investigation of the CD95/FADD homotypic death domain complex suggests lack of engagement of the CD95 C terminus.
Esposito D, Sankar A, Morgner N, Robinson CV, Rittinger K, Driscoll PC
Structure. 2010
PubMed ID: 20947025
Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt.
Wueest S, Rapold RA, Schoenle EJ, Konrad D
FEBS Lett. 2010
PubMed ID: 20828573
Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
Park J, Oh Y, Yoo L, Jung MS, Song WJ, Lee SH, Seo H, Chung KC
J Biol Chem. 2010
PubMed ID: 20696760
Detection of B cell lymphoma 2, tumor protein 53, and FAS gene transcripts in blood cells of patients with breast cancer.
Jaberipour M, Habibagahi M, Hosseini A, Abbasi M, Sobhani-Lari A, Talei A, Ghaderi A
Indian J Cancer. 2010
PubMed ID: 21131755
Expression of interleukin-17 in autoimmune dacryoadenitis in MRL/lpr mice.
Jie G, Jiang Q, Rui Z, Yifei Y
Curr Eye Res. 2010
PubMed ID: 20858106
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Fas inhibition attenuates lipopolysaccharide-induced apoptosis and cytokine release of rat type II alveolar epithelial cells.
Ma X, Xu D, Ai Y, Ming G, Zhao S
Mol Biol Rep. 2010
PubMed ID: 19823951
Are cell cycle and apoptosis genes associated with prostate cancer risk in North Indian population?
Mandal RK, Mittal RD
Urol Oncol. 2010
PubMed ID: 20822933
Genetic Variation in the FAS Gene and Associations with Acute Lung Injury.
Glavan BJ, Holden TD, Goss CH, Black RA, Neff MJ, Nathens AB, Martin TR, Wurfel MM, ARDSnet Investigators
Am J Respir Crit Care Med. 2010
PubMed ID: 20813889
Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency.
Wingender G, Krebs P, Beutler B, Kronenberg M
J Immunol. 2010
PubMed ID: 20660713
Qualitative and quantitative differences in the intensity of Fas-mediated intracellular signals determine life and death in T cells.
Shin MJ, Shim JH, Lee JY, Chae WJ, Lee HK, Morio T, Park JH, Chang EJ, Lee SK
Int J Hematol. 2010
PubMed ID: 20658220
Functional polymorphisms in cell death pathway genes and risk of renal cell carcinoma.
Zhu J, Qin C, Wang M, Yan F, Ju X, Meng X, Ding Q, Li P, Yang J, Cao Q, Zhang Z, Yin C
Mol Carcinog. 2010
PubMed ID: 20572163
Prognostic significance of CD95, P53, and BCL2 expression in extranodal non-Hodgkin's lymphoma.
Chatzitolios A, Venizelos I, Tripsiannis G, Anastassopoulos G, Papadopoulos N
Ann Hematol. 2010
PubMed ID: 20352431
Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor.
Cho HJ, Park SM, Hwang EM, Baek KE, Kim IK, Nam IK, Im MJ, Park SH, Bae S, Park JY, Yoo J
J Biol Chem. 2010
PubMed ID: 20558744
Mutational analysis of death receptor genes Fas, TRAILR1 and TRAILR2 in prostate carcinomas.
Park SW, Kim MS, Lee JY, Yoo NJ, Lee SH
APMIS. 2010
PubMed ID: 20666744
Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut.
Lee KM, Baris D, Zhang Y, Hosgood HD, Menashe I, Yeager M, Zahm SH, Wang SS, Purdue MP, Chanock S, Zheng T, Rothman N, Lan Q
Am J Hematol. 2010
PubMed ID: 20568250
Functional polymorphisms of the FAS/FASLG genes are associated with risk of alopecia areata in a Chinese population: a case-control analysis.
Fan X, Shangguan L, Li M, Li CY, Liu B
Br J Dermatol. 2010
PubMed ID: 20394629
Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice.
Aït-Azzouzene D, Kono DH, Gonzalez-Quintial R, McHeyzer-Williams LJ, Lim M, Wickramarachchi D, Gerdes T, Gavin AL, Skog P, McHeyzer-Williams MG, Nemazee D, Theofilopoulos AN
J Immunol. 2010
PubMed ID: 20554953
[Immune evasion of human lung carcinoma cell A549 suppressed by human lymphoma cell Jurkat via Fas/FasL pathway].
Wang H, Zhang G, Dai J, Min J
Zhongguo Fei Ai Za Zhi. 2010
PubMed ID: 20673483
FAS, FAS ligand, tumor infiltrating lymphocytes, and macrophages in malignant melanoma: an immunohistochemical study.
Bozdogan N, Bozdogan O, Pak I, Atasoy P
Int J Dermatol. 2010
PubMed ID: 20618494
NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy.
Gómez-Sintes R, Lucas JJ
J Clin Invest. 2010
PubMed ID: 20530871
In vivo regulation of Bcl6 and T follicular helper cell development.
Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, Dong X, Odegard JM, Kaech SM, Dent AL, Crotty S, Craft J
J Immunol. 2010
PubMed ID: 20519643
A Large-scale genetic association study of esophageal adenocarcinoma risk.
Liu CY, Wu MC, Chen F, Ter-Minassian M, Asomaning K, Zhai R, Wang Z, Su L, Heist RS, Kulke MH, Lin X, Liu G, Christiani DC
Carcinogenesis. 2010
PubMed ID: 20453000
Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymphoma.
Wu F, Wang P, Zhang J, Young LC, Lai R, Li L
Mol Cell Proteomics. 2010
PubMed ID: 20393185
Association of selected variants in genes involved in cell cycle and apoptosis with bladder cancer risk in North Indian population.
Gangwar R, Mittal RD
DNA Cell Biol. 2010
PubMed ID: 20380574
miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1.
Schickel R, Park SM, Murmann AE, Peter ME
Mol Cell. 2010
PubMed ID: 20620960
Somatic FAS mutations are common in patients with genetically undefined autoimmune lymphoproliferative syndrome.
Dowdell KC, Niemela JE, Price S, Davis J, Hornung RL, Oliveira JB, Puck JM, Jaffe ES, Pittaluga S, Cohen JI, Fleisher TA, Rao VK
Blood. 2010
PubMed ID: 20360470
NK cell regulation of CD4 T cell-mediated graft-versus-host disease.
Rivas MN, Hazzan M, Weatherly K, Gaudray F, Salmon I, Braun MY
J Immunol. 2010
PubMed ID: 20488796
Lupus serum IgG induces skin inflammation through the TNFR1 signaling pathway.
Deng GM, Liu L, Kyttaris VC, Tsokos GC
J Immunol. 2010
PubMed ID: 20483718
Mitochondrial damage in the trabecular meshwork of patients with glaucoma.
Izzotti A, Saccà SC, Longobardi M, Cartiglia C
Arch Ophthalmol. 2010
PubMed ID: 20547950
FAS and FASLG genetic variants and risk for second primary malignancy in patients with squamous cell carcinoma of the head and neck.
Lei D, Sturgis EM, Wang LE, Liu Z, Zafereo ME, Wei Q, Li G
Cancer Epidemiol Biomarkers Prev. 2010
PubMed ID: 20501759
Extra-cellular matrix suppresses expression of the apoptosis mediator Fas by epigenetic DNA methylation.
Thaler R, Karlic H, Spitzer S, Klaushofer K, Varga F
Apoptosis. 2010
PubMed ID: 20428952
PD-1 deficiency results in the development of fatal myocarditis in MRL mice.
Wang J, Okazaki IM, Yoshida T, Chikuma S, Kato Y, Nakaki F, Hiai H, Honjo T, Okazaki T
Int Immunol. 2010
PubMed ID: 20410257
Antigen-specific CD25- Foxp3- IFN-gamma(high) CD4+ T cells restrain the development of experimental allergic encephalomyelitis by suppressing Th17.
Wildbaum G, Zohar Y, Karin N
Am J Pathol. 2010
PubMed ID: 20382706
Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.
Sombekke MH, Arteta D, van de Wiel MA, Crusius JB, Tejedor D, Killestein J, Martínez A, Peña AS, Polman CH, Uitdehaag BM
Mult Scler. 2010
PubMed ID: 20378664
Genetic analysis of the role of tumor necrosis factor receptors in functional outcome after traumatic brain injury in mice.
Yang J, You Z, Kim HH, Hwang SK, Khuman J, Guo S, Lo EH, Whalen MJ
J Neurotrauma. 2010
PubMed ID: 20205514
CD95 is cytoprotective for intestinal epithelial cells in colitis.
Park SM, Chen L, Zhang M, Ashton-Rickardt P, Turner JR, Peter ME
Inflamm Bowel Dis. 2010
PubMed ID: 20049944
CD95 promotes tumour growth.
Chen L, Park SM, Tumanov AV, Hau A, Sawada K, Feig C, Turner JR, Fu YX, Romero IL, Lengyel E, Peter ME
Nature. 2010
PubMed ID: 20505730
Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma.
Zhai R, Chen F, Liu G, Su L, Kulke MH, Asomaning K, Lin X, Heist RS, Nishioka NS, Sheu CC, Wain JC, Christiani DC
J Clin Oncol. 2010
PubMed ID: 20385987
Fas and FasL Polymorphisms Are Not Associated with Acute Myeloid Leukemia Risk in Koreans.
Kim HJ, Jin XM, Kim HN, Lee IK, Park KS, Park MR, Jo DY, Won JH, Kwak JY, Kim HJ, Choi JS, Juhng SW, Choi C
DNA Cell Biol. 2010
PubMed ID: 20438363
[The study of expression of apoptosis receptors (CD95+) on the surface of neutrophils from cervical secretion of women with chlamydial infection and the possibility of its correction by magnetic laser radiation].
Gizinger OA, Ishpakhtina KG
Vopr Kurortol Fizioter Lech Fiz Kult. 2010
PubMed ID: 20737708
[Effect of all-trans retinoic acid on the proliferation of and Fas protein expression in human malignant melanoma A375 cells].
Zhou Y, Yang J, Zhao H, Li HJ
Sichuan Da Xue Xue Bao Yi Xue Ban. 2010
PubMed ID: 20629322
The role of skin-derived dendritic cells in CD8+ T cell priming following immunization with lentivectors.
Furmanov K, Elnekave M, Lehmann D, Clausen BE, Kotton DN, Hovav AH
J Immunol. 2010
PubMed ID: 20357252
Dendritic cells and Stat3 are essential for CD137-induced CD8 T cell activation-induced cell death.
Zhang B, Zhang Y, Niu L, Vella AT, Mittler RS
J Immunol. 2010
PubMed ID: 20351189
Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice.
Kyttaris VC, Zhang Z, Kuchroo VK, Oukka M, Tsokos GC
J Immunol. 2010
PubMed ID: 20308633
Lysosome-dependent Ca(2+) release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts.
Zhang F, Xia M, Li PL
Am J Physiol Cell Physiol. 2010
PubMed ID: 20200208
Decreased expression of Fli-1 in bone marrow-derived haematopoietic cells significantly affects disease development in Murphy Roths Large/lymphoproliferation (MRL/lpr) mice.
Molano I, Mathenia J, Ruiz P, Gilkeson GS, Zhang XK
Clin Exp Immunol. 2010
PubMed ID: 20015093
TNF superfamily gene polymorphism as prognostic factor in early breast cancer.
Jung JH, Chae YS, Moon JH, Kang BW, Kim JG, Sohn SK, Park JY, Lee MH, Park HY
J Cancer Res Clin Oncol. 2010
PubMed ID: 19890662
CD4(+)CD25(+) regulatory T cells utilize FasL as a mechanism to restrict DC priming functions in cutaneous immune responses.
Gorbachev AV, Fairchild RL
Eur J Immunol. 2010
PubMed ID: 20405474
[Effect of formaldehyde on expressions of Fas apoptosis pathway-related genes of ovary tissues in female rats].
Peng G, Zhong C, Zhang Q, Xie Y, Gong F
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010
PubMed ID: 20448356
Underexpression and overexpression of Fas and Fas ligand: a double-edged sword.
Randhawa SR, Chahine BG, Lowery-Nordberg M, Cotelingam JD, Casillas AM
Ann Allergy Asthma Immunol. 2010
PubMed ID: 20408337
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes Immun. 2010
PubMed ID: 20237496
Polymorphisms of FAS and FAS ligand genes and risk of skin cancer.
Qureshi A, Nan H, Dyer M, Han J
J Dermatol Sci. 2010
PubMed ID: 20219325
Melatonin protects CD4+ T cells from activation-induced cell death by blocking NFAT-mediated CD95 ligand upregulation.
Pedrosa AM, Weinlich R, Mognol GP, Robbs BK, Viola JP, Campa A, Amarante-Mendes GP
J Immunol. 2010
PubMed ID: 20181888
International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants.
Truong T, Sauter W, McKay JD, Hosgood HD, Gallagher C, Amos CI, Spitz M, Muscat J, Lazarus P, Illig T, Wichmann HE, Bickeböller H, Risch A, Dienemann H, Zhang ZF, Naeim BP, Yang P, Zienolddiny S, Haugen A, Le Marchand L, Hong YC, Kim JH, Duell EJ, Andrew AS, Kiyohara C, Shen H, Matsuo K, Suzuki T, Seow A, Ng DP, Lan Q, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Constantinescu V, Bencko V, Foretova L, Janout V, Caporaso NE, Albanes D, Thun M, Landi MT, Trubicka J, Lener M, Lubinski J, EPIC-lung, Wang Y, Chabrier A, Boffetta P, Brennan P, Hung RJ
Carcinogenesis. 2010
PubMed ID: 20106900
Soluble Fas: a useful marker of inflammation and cardiovascular diseases in uremic patients.
El-Agroudy AE, El-Baz A
Clin Exp Nephrol. 2010
PubMed ID: 20101431
Downregulation of Fas gene expression in Sézary syndrome is associated with promoter hypermethylation.
Jones CL, Wain EM, Chu CC, Tosi I, Foster R, McKenzie RC, Whittaker SJ, Mitchell TJ
J Invest Dermatol. 2010
PubMed ID: 19759548
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.
Pradelli LA, Bénéteau M, Chauvin C, Jacquin MA, Marchetti S, Muñoz-Pinedo C, Auberger P, Pende M, Ricci JE
Oncogene. 2010
PubMed ID: 19966861
Clinical significance of Fas and FasL protein expression in gastric carcinoma and local lymph node tissues.
Li Q, Peng J, Li XH, Liu T, Liang QC, Zhang GY
World J Gastroenterol. 2010
PubMed ID: 20222173
Analysis of common germline polymorphisms as prognostic factors in patients with lymph node-positive breast cancer.
Knechtel G, Hofmann G, Gerger A, Renner W, Langsenlehner T, Szkandera J, Wolf G, Samonigg H, Krippl P, Langsenlehner U
J Cancer Res Clin Oncol. 2010
PubMed ID: 20204402
A novel role of microtubular cytoskeleton in the dynamics of caspase-dependent Fas/CD95 death receptor complexes during apoptosis.
Doma E, Chakrabandhu K, Hueber AO
FEBS Lett. 2010
PubMed ID: 20138036
Lack of Fas-pathway gene mutations in primary resected esophageal squamous cell carcinoma.
Ko CL, Yang CY, Chung CY, Wen MC, Hsu CP, Miaw J, Hsia JY
Chang Gung Med J. 2010
PubMed ID: 20438666
[Qingli shengjing pills decrease apoptosis of germ cells and expressions of fas and fasL in male mice infected with Escherichia coli]
Yu AL, Deng W, Jiao P, Shen JY, Zhu XM, Liu L, Zhuang DM
Zhonghua Nan Ke Xue. 2010
PubMed ID: 20369561
Correlation of Fas/FasL expression to cell apoptosis in Epstein-Barr virus-associated gastric carcinoma.
He D, Xiao L, Chen JN, Liang Q, Shao CK
Chin J Cancer. 2010
PubMed ID: 20193111
Fas receptor is required for estrogen deficiency-induced bone loss in mice.
Kovacic N, Grcevic D, Katavic V, Lukic IK, Grubisic V, Mihovilovic K, Cvija H, Croucher PI, Marusic A
Lab Invest. 2010
PubMed ID: 20084056
Polymorphisms in promoter region of FAS and FASL gene and risk of gastric cardiac adenocarcinoma.
Zhou RM, Wang N, Chen ZF, Duan YN, Sun DL, Li Y
J Gastroenterol Hepatol. 2010
PubMed ID: 20074157
Suppression of ERK signaling evokes autocrine Fas-mediated death in arachidonic acid-treated human chronic myeloid leukemia K562 cells.
Chen KC, Liu WH, Chang LS
J Cell Physiol. 2010
PubMed ID: 19927299
Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.
Verbrugge I, Maas C, Heijkoop M, Verheij M, Borst J
Cell Death Differ. 2010
PubMed ID: 19798106
The FAS gene, brain volume, and disease progression in Alzheimer's disease.
Erten-Lyons D, Jacobson A, Kramer P, Grupe A, Kaye J
Alzheimers Dement. 2010
PubMed ID: 19766542
CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site.
Letellier E, Kumar S, Sancho-Martinez I, Krauth S, Funke-Kaiser A, Laudenklos S, Konecki K, Klussmann S, Corsini NS, Kleber S, Drost N, Neumann A, Lévi-Strauss M, Brors B, Gretz N, Edler L, Fischer C, Hill O, Thiemann M, Biglari B, Karray S, Martin-Villalba A
Immunity. 2010
PubMed ID: 20153221
TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus.
Nickerson KM, Christensen SR, Shupe J, Kashgarian M, Kim D, Elkon K, Shlomchik MJ
J Immunol. 2010
PubMed ID: 20089701
Polymorphisms in the apoptosis-associated genes FAS and FASL and risk of oral cancer and malignant potential of oral premalignant lesions in a Taiwanese population.
Wang LH, Ting SC, Chen CH, Tsai CC, Lung O, Liu TC, Lee CW, Wang YY, Tsai CL, Lin YC
J Oral Pathol Med. 2010
PubMed ID: 20359312
Polymorphisms of FAS and FAS ligand genes in preeclamptic women.
Ciarmela P, Boschi S, Bloise E, Marozio L, Benedetto C, Castellucci M, Petraglia F
Eur J Obstet Gynecol Reprod Biol. 2010
PubMed ID: 19926197
Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity in lpr mice on a C57BL/6 background.
Chen L, Guo L, Tian J, Zheng B, Han S
Clin Exp Immunol. 2010
PubMed ID: 19922498
FAS-670A/G polymorphism: A biomarker for the metastasis of nasopharyngeal carcinoma in a Chinese population.
Zhu Q, Wang T, Ren J, Hu K, Liu W, Wu G
Clin Chim Acta. 2010
PubMed ID: 19895798
In toxic demyelination oligodendroglial cell death occurs early and is FAS independent.
Hesse A, Wagner M, Held J, Brück W, Salinas-Riester G, Hao Z, Waisman A, Kuhlmann T
Neurobiol Dis. 2010
PubMed ID: 19853662
Non-apoptotic Fas signaling regulates invasiveness of glioma cells and modulates MMP-2 activity via NFkappaB-TIMP-2 pathway.
Wisniewski P, Ellert-Miklaszewska A, Kwiatkowska A, Kaminska B
Cell Signal. 2010
PubMed ID: 19788921
PDCA expression by B lymphocytes reveals important functional attributes.
Vinay DS, Kim CH, Chang KH, Kwon BS
J Immunol. 2010
PubMed ID: 20018628
Immune effectors required for hepatitis B virus clearance.
Yang PL, Althage A, Chung J, Maier H, Wieland S, Isogawa M, Chisari FV
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20080755
Altered CD28 and CD95 mRNA expression in peripheral blood mononuclear cells from elderly patients with primary non-small cell lung cancer.
Wang L, Pan XD, Xie Y, Zhang GB, Jiang M, Zheng L, Wang JH, Shi JF, Zhang XG
Chin Med J (Engl). 2010
PubMed ID: 20137575
LMNA E82K mutation activates FAS and mitochondrial pathways of apoptosis in heart tissue specific transgenic mice.
Lu D, Lian H, Zhang X, Shao H, Huang L, Qin C, Zhang L
PLoS One. 2010
PubMed ID: 21151901
Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.
Humphreys EH, Williams KT, Adams DH, Afford SC
PLoS One. 2010
PubMed ID: 21103345
Small molecules regulating apoptosis in the synovium in rheumatoid arthritis.
Dubikov AI, Kalinichenko SG
Scand J Rheumatol. 2010
PubMed ID: 20936988
Soluble Fas might serve as a diagnostic tool for gastric adenocarcinoma.
Boroumand-Noughabi S, Sima HR, Ghaffarzadehgan K, Jafarzadeh M, Raziee HR, Hosseinnezhad H, Moaven O, Rajabi-Mashhadi MT, Azarian AA, Mashhadinejad M, Tavakkol-Afshari J
BMC Cancer. 2010
PubMed ID: 20534173
Up-regulation of Fas reverses cisplatin resistance of human small cell lung cancer cells.
Wu W, Wang HD, Guo W, Yang K, Zhao YP, Jiang YG, He P
J Exp Clin Cancer Res. 2010
PubMed ID: 20470393
Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
Ban HJ, Heo JY, Oh KS, Park KJ
BMC Genet. 2010
PubMed ID: 20416077
Akt activity protects rheumatoid synovial fibroblasts from Fas-induced apoptosis by inhibition of Bid cleavage.
García S, Liz M, Gómez-Reino JJ, Conde C
Arthritis Res Ther. 2010
PubMed ID: 20187936
Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass.
Kunes P, Mandak J, Harrer J, Kolackova M, Andrys C, Holicka M, Krejsek J
Perfusion. 2010
PubMed ID: 20164160
Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth.
Ryckman KK, Morken NH, White MJ, Velez DR, Menon R, Fortunato SJ, Magnus P, Williams SM, Jacobsson B
PLoS One. 2010
PubMed ID: 20140262
Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.
Guillen-Ahlers H, Suckow MA, Castellino FJ, Ploplis VA
PLoS One. 2010
PubMed ID: 20140201
Fas gene polymorphisms in systemic lupus erythematosus and serum levels of some apoptosis-related molecules.
Araste JM, Sarvestani EK, Aflaki E, Amirghofran Z
Immunol Invest. 2010
PubMed ID: 20064083
Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas.
Sorice M, Matarrese P, Manganelli V, Tinari A, Giammarioli AM, Mattei V, Misasi R, Garofalo T, Malorni W
PLoS One. 2010
PubMed ID: 20052288
Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice.
Wueest S, Rapold RA, Schumann DM, Rytka JM, Schildknecht A, Nov O, Chervonsky AV, Rudich A, Schoenle EJ, Donath MY, Konrad D
J Clin Invest. 2010
PubMed ID: 19955656
CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis.
Singh N, Yamamoto M, Takami M, Seki Y, Takezaki M, Mellor AL, Iwashima M
J Immunol. 2010
PubMed ID: 19949106
Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure.
Zou Y, Chen T, Han M, Wang H, Yan W, Song G, Wu Z, Wang X, Zhu C, Luo X, Ning Q
J Immunol. 2010
PubMed ID: 19949088
Taiwan cobra phospholipase A2-elicited JNK activation is responsible for autocrine fas-mediated cell death and modulating Bcl-2 and Bax protein expression in human leukemia K562 cells.
Chen KC, Liu WH, Chang LS
J Cell Biochem. 2010
PubMed ID: 19937732
Effect of simvastatin on endothelial cell apoptosis mediated by Fas and TNF-alpha.
Acquavella N, Quiroga MF, Wittig O, Cardier JE
Cytokine. 2010
PubMed ID: 19932975
Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.
van Blitterswijk WJ, Klarenbeek JB, van der Luit AH, Alderliesten MC, van Lummel M, Verheij M
Biochem J. 2010
PubMed ID: 19824885
Monitoring of CD95 and CD38 expression in peripheral blood T lymphocytes during active human cytomegalovirus infection after orthotopic liver transplantation.
Wang Y, Liu Y, Han R, Li Q, Yao Z, Niu W, Yuan Y, Tang Z, Zhu Z, Shen Z
J Gastroenterol Hepatol. 2010
PubMed ID: 19817952
AKT controls human first trimester trophoblast cell sensitivity to FAS-mediated apoptosis by regulating XIAP expression.
Straszewski-Chavez SL, Abrahams VM, Aldo PB, Romero R, Mor G
Biol Reprod. 2010
PubMed ID: 19726736
Differential role of the Fas/Fas ligand apoptotic pathway in inflammation and lung fibrosis associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia and acute respiratory distress syndrome.
Lopez AD, Avasarala S, Grewal S, Murali AK, London L
J Immunol. 2009
PubMed ID: 20007588
Selection of cases and controls for the nested case-control study within the Japan Collaborative Cohort Study: the First-wave.
Tamakoshi A, Suzuki K, Ito Y, Watanabe Y, Inaba Y, Tajima K, Nakachi K, Ohno Y, JACC Study Group
Asian Pac J Cancer Prev. 2009
PubMed ID: 20553075
The FAS -670A>G polymorphism influences susceptibility to systemic sclerosis phenotypes.
Broen J, Gourh P, Rueda B, Coenen M, Mayes M, Martin J, Arnett FC, Radstake TR, European Consortium on Systemic Sclerosis Genetics
Arthritis Rheum. 2009
PubMed ID: 19950259
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
Hosgood HD, Zhang L, Shen M, Berndt SI, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan Q
Occup Environ Med. 2009
PubMed ID: 19773279
Deletion of putative intronic control sequences does not alter cell or stage specific expression of Cr2.
Roundy KM, Weis JJ, Weis JH
Mol Immunol. 2009
PubMed ID: 19740539
CD95 engagement mediates actin-independent and -dependent apoptotic signals.
Chaigne-Delalande B, Mahfouf W, Daburon S, Moreau JF, Legembre P
Cell Death Differ. 2009
PubMed ID: 19680267
Increased expression of CD154 and FAS in SLE patients' lymphocytes.
Manea ME, Mueller RB, Dejica D, Sheriff A, Schett G, Herrmann M, Kern P
Rheumatol Int. 2009
PubMed ID: 19404646
Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells.
Shawgo ME, Shelton SN, Robertson JD
J Biol Chem. 2009
PubMed ID: 19758996
Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus.
Lartigue A, Colliou N, Calbo S, François A, Jacquot S, Arnoult C, Tron F, Gilbert D, Musette P
J Immunol. 2009
PubMed ID: 19841185
Identification, characterisation and regulation by CD40 activation of novel CD95 splice variants in CD95-apoptosis-resistant, human, B-cell non-Hodgkin's lymphoma.
Lajmanovich A, Ribeyron JB, Florin A, Fournier A, Pasquier MA, Duley S, Chauvet M, Plumas J, Bonnefoix T, Gressin R, Leroux D, Callanan MB
Exp Cell Res. 2009
PubMed ID: 19751723
p16INK4A sensitizes human leukemia cells to FAS- and glucocorticoid-induced apoptosis via induction of BBC3/Puma and repression of MCL1 and BCL2.
Obexer P, Hagenbuchner J, Rupp M, Salvador C, Holzner M, Deutsch M, Porto V, Kofler R, Unterkircher T, Ausserlechner MJ
J Biol Chem. 2009
PubMed ID: 19737931
Serum sFas, leptin, and VEGF in patients with ovarian cancer and benign tumors.
Vysotskii MM, Digaeva MA, Kushlinskii NE, Abbasova SG, Laktionov KP, Ermilova VD, Bakhoeva KA, Kryuk YV, Manukhin IB
Bull Exp Biol Med. 2009
PubMed ID: 20396799
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice.
Ishikawa T, Yamada H, Oyamada A, Goshima F, Nishiyama Y, Yoshikai Y
J Virol. 2009
PubMed ID: 19740996
Virion-associated Vpr of human immunodeficiency virus type 1 triggers activation of apoptotic events and enhances fas-induced apoptosis in human T cells.
Arokium H, Kamata M, Chen I
J Virol. 2009
PubMed ID: 19692467
Fas expression in conjunctival epithelial cells of patients with cystic fibrosis.
Mrugacz M
J Interferon Cytokine Res. 2009
PubMed ID: 19642903
Effects of diethylstilbestrol on programmed oocyte death and induction of polyovular follicles in neonatal mouse ovaries.
Kim H, Nakajima T, Hayashi S, Chambon P, Watanabe H, Iguchi T, Sato T
Biol Reprod. 2009
PubMed ID: 19553606
Alternative Fas-mediated cell death pathway is dependent on the different cleavage patterns of procaspase-8.
Li Y, Qi L, Iwao A, Kihira K, Dida F, Song Z, Azuma E, Komada Y
Mol Cell Biochem. 2009
PubMed ID: 19521670
The distribution and intracellular location of Fas and Fas Ligand following gastric carcinogenesis: Fas Ligand expressing gastric carcinoma cells can inhibit local immune response.
Liu H, Ubukata H, Tabuchi T, Nakachi T, Nagata H, Shimazaki J, Motohashi G, Konishi S, Nishimura M, Satani T, Hong J, Nakada I, Saniabadi AR, Tabuchi T
Mol Cell Biochem. 2009
PubMed ID: 19458913
Fas expression on peripheral blood lymphocytes in systemic lupus erythematosus: relation to the organ damage and lymphocytes apoptosis.
Li LH, Li WX, Wu O, Zhang GQ, Pan HF, Li XP, Xu JH, Dai H, Ye DQ
Mol Biol Rep. 2009
PubMed ID: 19020991
Cytolytic T cells induce ceramide-rich platforms in target cell membranes to initiate graft-versus-host disease.
Rotolo JA, Stancevic B, Lu SX, Zhang J, Suh D, King CG, Kappel LW, Murphy GF, Liu C, Fuks Z, van den Brink MR, Kolesnick R
Blood. 2009
PubMed ID: 19666872
Cancer and soluble FAS.
Abbasova SG, Vysotskii MM, Ovchinnikova LK, Obusheva MN, Digaeva MA, Britvin TA, Bahoeva KA, Karabekova ZK, Kazantzeva IA, Mamedov UR, Manuchin IB, Davidov MI
Bull Exp Biol Med. 2009
PubMed ID: 20396760
Membrane-bound Fas ligand only is essential for Fas-induced apoptosis.
O' Reilly LA, Tai L, Lee L, Kruse EA, Grabow S, Fairlie WD, Haynes NM, Tarlinton DM, Zhang JG, Belz GT, Smyth MJ, Bouillet P, Robb L, Strasser A
Nature. 2009
PubMed ID: 19794494
A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.
Young RP, Hopkins RJ, Hay BA, Epton MJ, Mills GD, Black PN, Gardner HD, Sullivan R, Gamble GD
Postgrad Med J. 2009
PubMed ID: 19789190
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.
Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I
J Clin Invest. 2009
PubMed ID: 19741297
CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.
Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U
J Immunol. 2009
PubMed ID: 19734217
Aberrant integrin activation induces p38 MAPK phosphorylation resulting in suppressed Fas-mediated apoptosis in T cells: implications for rheumatoid arthritis.
Lin YP, Su CC, Huang JY, Lin HC, Cheng YJ, Liu MF, Yang BC
Mol Immunol. 2009
PubMed ID: 19698994
Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality.
Ji G, Gu A, Hu F, Wang S, Liang J, Xia Y, Lu C, Song L, Fu G, Wang X
Hum Reprod. 2009
PubMed ID: 19542541
Raft component GD3 associates with tubulin following CD95/Fas ligation.
Sorice M, Matarrese P, Tinari A, Giammarioli AM, Garofalo T, Manganelli V, Ciarlo L, Gambardella L, Maccari G, Botta M, Misasi R, Malorni W
FASEB J. 2009
PubMed ID: 19509307
Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Kim JG, Chae YS, Sohn SK, Moon JH, Ryoo HM, Bae SH, Kum Y, Jeon SW, Lim KH, Kang BM, Park IJ, Choi GS, Jun SH
Cancer Chemother Pharmacol. 2009
PubMed ID: 19219602
Active transcription of the human FAS/CD95/TNFRSF6 gene involves the p53 family.
Schilling T, Schleithoff ES, Kairat A, Melino G, Stremmel W, Oren M, Krammer PH, Müller M
Biochem Biophys Res Commun. 2009
PubMed ID: 19615968
Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.
Reis-Sobreiro M, Gajate C, Mollinedo F
Oncogene. 2009
PubMed ID: 19561642
The role of IL-23/IL-17 axis in lupus nephritis.
Zhang Z, Kyttaris VC, Tsokos GC
J Immunol. 2009
PubMed ID: 19657089
X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms.
Sharma R, Deshmukh US, Zheng L, Fu SM, Ju ST
J Immunol. 2009
PubMed ID: 19648271
Fas ligand expression in lynch syndrome-associated colorectal tumours.
Koornstra JJ, de Jong S, Boersma-van Eck W, Zwart N, Hollema H, de Vries EG, Kleibeuker JH
Pathol Oncol Res. 2009
PubMed ID: 19067240
Augmented TLR9-induced Btk activation in PIR-B-deficient B-1 cells provokes excessive autoantibody production and autoimmunity.
Kubo T, Uchida Y, Watanabe Y, Abe M, Nakamura A, Ono M, Akira S, Takai T
J Exp Med. 2009
PubMed ID: 19687229
Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement.
Tan NY, Li JM, Stocker R, Khachigian LM
Circ Res. 2009
PubMed ID: 19628789
The relationship of the Fas 670 A/G gene polymorphism with cardiovascular risk factors in polycystic ovary syndrome (PCOS) patients.
Cetinkalp S, Erdogan M, Karadeniz M, Berdeli A, Tamsel S, Ozgen AG, Saygili F, Yilmaz C
Gynecol Endocrinol. 2009
PubMed ID: 19718569
A single-nucleotide polymorphism (-670) of the maternal Fas gene is associated with intrauterine growth restriction.
Robinson R, Hsu CD, Chesebro AL, Nguyen J, Ali N, Maramreddy H, Parton LA
Am J Obstet Gynecol. 2009
PubMed ID: 19716115
Antigen presented by tumors in vivo determines the nature of CD8+ T-cell cytotoxicity.
Shanker A, Brooks AD, Jacobsen KM, Wine JW, Wiltrout RH, Yagita H, Sayers TJ
Cancer Res. 2009
PubMed ID: 19654302
Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon.
Saint Fleur S, Hoshino A, Kondo K, Egawa T, Fujii H
Blood. 2009
PubMed ID: 19528538
Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
Eur Urol. 2009
PubMed ID: 19692168
The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.
Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Brüstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A
Cell Stem Cell. 2009
PubMed ID: 19664992
Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD.
Ben Aleya W, Sfar I, Mouelhi L, Aouadi H, Makhlouf M, Ayed-Jendoubi S, Matri S, Filali A, Najjar T, Ben Abdallah T, Ayed K, Gorgi Y
World J Gastroenterol. 2009
PubMed ID: 19653342
The apoptotic paradox in retinoblastoma.
Sitorus RS, Gumay S, van der Valk P
Ann N Y Acad Sci. 2009
PubMed ID: 19723039
Common genetic variants in candidate genes and risk of familial lymphoid malignancies.
Liang XS, Caporaso N, McMaster ML, Ng D, Landgren O, Yeager M, Chanock S, Goldin LR
Br J Haematol. 2009
PubMed ID: 19573080
FAS and FAS ligand polymorphisms in the promoter regions and risk of gastric cancer in Southern China.
Wang M, Wu D, Tan M, Gong W, Xue H, Shen H, Zhang Z
Biochem Genet. 2009
PubMed ID: 19565204
Nucleotide-hydrolyzing antibodies from the sera of autoimmune-prone MRL-lpr/lpr mice.
Andryushkova AA, Kuznetsova IA, Orlovskaya IA, Buneva VN, Nevinsky GA
Int Immunol. 2009
PubMed ID: 19556305
Peculiar subcellular localization of Fas antigen in human and mouse spermatozoa.
Starace D, Muciaccia B, Morgante E, Russo MA, Pensini S, D'agostino A, De Cesaris P, Filippini A, Ziparo E, Riccioli A
Microsc Res Tech. 2009
PubMed ID: 19263494
Protein kinase Cepsilon inhibits UVR-induced expression of FADD, an adaptor protein, linked to both Fas- and TNFR1-mediated apoptosis.
Aziz MH, Sundling KE, Dreckschmidt NE, Verma AK
J Invest Dermatol. 2009
PubMed ID: 19194472
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus.
Kono DH, Haraldsson MK, Lawson BR, Pollard KM, Koh YT, Du X, Arnold CN, Baccala R, Silverman GJ, Beutler BA, Theofilopoulos AN
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19574451
PTEN identified as important risk factor of chronic obstructive pulmonary disease.
Hosgood HD, Menashe I, He X, Chanock S, Lan Q
Respir Med. 2009
PubMed ID: 19625176
IL-2 regulates CD103 expression on CD4+ T cells in Scurfy mice that display both CD103-dependent and independent inflammation.
Sharma R, Sung SS, Abaya CE, Ju AC, Fu SM, Ju ST
J Immunol. 2009
PubMed ID: 19553521
[Genetic polymorphisms in STK15 and MMP-2 associated susceptibility to esophageal cancer in Mongolian population]
Chen XB, Chen GL, Liu JN, Yang JZ, Yu DK, Lin DX, Tan W
Zhonghua Yu Fang Yi Xue Za Zhi. 2009
PubMed ID: 19954064
Expression of Fas/FasL in patients with oral lichen planus.
Hadzi-Mihailovic M, Raybaud H, Monteil R, Jankovic L
J BUON. 2009
PubMed ID: 19810143
Caspase-3-mediated cyclic stretch-induced myoblast apoptosis via a Fas/FasL-independent signaling pathway during myogenesis.
Liu J, Liu J, Mao J, Yuan X, Lin Z, Li Y
J Cell Biochem. 2009
PubMed ID: 19415683
A new function of the Fas-FasL pathway in macrophage activation.
Chakour R, Allenbach C, Desgranges F, Charmoy M, Mauel J, Garcia I, Launois P, Louis J, Tacchini-Cottier F
J Leukoc Biol. 2009
PubMed ID: 19380712
Hepatitis C virus and disrupted interferon signaling promote lymphoproliferation via type II CD95 and interleukins.
Machida K, Tsukiyama-Kohara K, Sekiguch S, Seike E, Tóne S, Hayashi Y, Tobita Y, Kasama Y, Shimizu M, Takahashi H, Taya C, Yonekawa H, Tanaka N, Kohara M
Gastroenterology. 2009
PubMed ID: 19362089
Apoptotic mechanisms in fulminant hepatic failure: potential therapeutic target.
Singhal S, Jain S, Kohaar I, Singla M, Gondal R, Kar P
Appl Immunohistochem Mol Morphol. 2009
PubMed ID: 19077906
The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals.
Yanaba K, Bouaziz JD, Matsushita T, Tsubata T, Tedder TF
J Immunol. 2009
PubMed ID: 19494269
CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling.
Strauss G, Lindquist JA, Arhel N, Felder E, Karl S, Haas TL, Fulda S, Walczak H, Kirchhoff F, Debatin KM
J Exp Med. 2009
PubMed ID: 19487421
[Up-regulation of Fas is related to apoptosis of HeLa cells induced by co-immobilized TNF-alpha/IFN-gamma].
Sun R, Fang Z, Zheng J, Wu Z, Qiu J, Li W, Zhao D, Liang S, Guan Y
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009
PubMed ID: 19634684
Fas-mediated apoptotic signaling in the mouse brain following reovirus infection.
Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL
J Virol. 2009
PubMed ID: 19321603
Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity.
Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG
Arterioscler Thromb Vasc Biol. 2009
PubMed ID: 19286630
Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis.
Shaker OG, Hammam O, Salehd A, el-Leithy T, Wishahi M
Clin Biochem. 2009
PubMed ID: 19272297
Serum sFas and tumor tissue FasL negatively correlated with survival in Egyptian patients suffering from breast ductal carcinoma.
El-Sarha AI, Magour GM, Zaki SM, El-Sammak MY
Pathol Oncol Res. 2009
PubMed ID: 19015953
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
FasL cross-linking inhibits activation of human peripheral T cells.
Paulsen M, Mathew B, Qian J, Lettau M, Kabelitz D, Janssen O
Int Immunol. 2009
PubMed ID: 19332441
Exercise affects tissue lymphocyte apoptosis via redox-sensitive and Fas-dependent signaling pathways.
Krüger K, Frost S, Most E, Völker K, Pallauf J, Mooren FC
Am J Physiol Regul Integr Comp Physiol. 2009
PubMed ID: 19261913
FAS -1,377 G/A polymorphism is associated with cancer susceptibility: evidence from 10,564 cases and 12,075 controls.
Qiu LX, Shi J, Yuan H, Jiang X, Xue K, Pan HF, Li J, Zheng MH
Hum Genet. 2009
PubMed ID: 19225810
Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
Environ Mol Mutagen. 2009
PubMed ID: 19170196
Low FAS/CD95 expression by CTCL correlates with reduced sensitivity to apoptosis that can be restored by FAS upregulation.
Wu J, Nihal M, Siddiqui J, Vonderheid EC, Wood GS
J Invest Dermatol. 2009
PubMed ID: 18923451
The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differentiation.
Mise-Omata S, Kuroda E, Sugiura T, Yamashita U, Obata Y, Doi TS
J Immunol. 2009
PubMed ID: 19342670
Tetrazolium violet induces apoptosis via caspases-8, -9 activation and Fas/FasL up-regulation in rat C6 glioma cells.
Cai CF, Feng L, Wang L, Kong QZ, Zhao YF
Arch Pharm Res. 2009
PubMed ID: 19407976
Dynamic expressions of liver tissue apoptosis-related genes of Vibrio vulnificus sepsis rats and the effects of antibacterial agents.
Lu Z, Li M, Liang H, Qiu Q, Yang G, Zhou T, Hong G
J Huazhong Univ Sci Technolog Med Sci. 2009
PubMed ID: 19399403
Constitutive pro-apoptotic molecules are differentially expressed in the fetal and adult mouse eye.
Montalvo V, Gery I
Curr Eye Res. 2009
PubMed ID: 19373582
Determination of genetic predisposition to patent ductus arteriosus in preterm infants.
Dagle JM, Lepp NT, Cooper ME, Schaa KL, Kelsey KJ, Orr KL, Caprau D, Zimmerman CR, Steffen KM, Johnson KJ, Marazita ML, Murray JC
Pediatrics. 2009
PubMed ID: 19336370
ICOS controls effector function but not trafficking receptor expression of kidney-infiltrating effector T cells in murine lupus.
Odegard JM, DiPlacido LD, Greenwald L, Kashgarian M, Kono DH, Dong C, Flavell RA, Craft J
J Immunol. 2009
PubMed ID: 19299705
Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.
Crowley SD, Vasievich MP, Ruiz P, Gould SK, Parsons KK, Pazmino AK, Facemire C, Chen BJ, Kim HS, Tran TT, Pisetsky DS, Barisoni L, Prieto-Carrasquero MC, Jeansson M, Foster MH, Coffman TM
J Clin Invest. 2009
PubMed ID: 19287096
Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction.
Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Katsuya T, Awata N, Kato N, Ogihara T, Rakugi H
Hypertens Res. 2009
PubMed ID: 19262492
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS).
Dowdell KC, Pesnicak L, Hoffmann V, Steadman K, Remaley AT, Cohen JI, Straus SE, Rao VK
Exp Hematol. 2009
PubMed ID: 19217201
Expression of Fas and Fas ligand in human testicular germ cell tumours.
Baldini E, Ulisse S, Marchioni E, Di Benedetto A, Giovannetti G, Petrangeli E, Sentinelli S, Donnorso RP, Reale MG, Mottolese M, Gandini L, Lenzi A, D'Armiento M
Int J Androl. 2009
PubMed ID: 17916181
Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2.
Zhang Y, Liu Q, Zhang M, Yu Y, Liu X, Cao X
J Immunol. 2009
PubMed ID: 19265159
Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice.
Blair PA, Chavez-Rueda KA, Evans JG, Shlomchik MJ, Eddaoudi A, Isenberg DA, Ehrenstein MR, Mauri C
J Immunol. 2009
PubMed ID: 19265127
Genetic variants in the candidate genes of the apoptosis pathway and susceptibility to chronic myeloid leukemia.
Kim DH, Xu W, Ma C, Liu X, Siminovitch K, Messner HA, Lipton JH
Blood. 2009
PubMed ID: 19141860
[The levels of soluble CD95 antigen and CD95+ mononuclear cells in patients with chronic obstructive lung diseases]
Kubysheva NI, Postnikova LB, Presniakova NB, Novikov VV
Klin Lab Diagn. 2009
PubMed ID: 19391241
Effect of Fas -670 A/G gene polymorphism on corneal allograft endothelial rejection.
Jahadi Hosseini HR, Kamali Sarvestani E, Akbari M, Mosallaei M
Iran J Immunol. 2009
PubMed ID: 19293475
Polymorphisms in the FAS and FASL genes and survival of early stage non-small cell lung cancer.
Park JY, Lee WK, Jung DK, Choi JE, Park TI, Lee EB, Cho S, Park JY, Cha SI, Kim CH, Kam S, Jung TH, Jheon S
Clin Cancer Res. 2009
PubMed ID: 19240174
End-organ damage in a mouse model of fulminant liver inflammation requires CD4+ T cell production of IFN-gamma but is independent of Fas.
Robinson RT, Wang J, Cripps JG, Milks MW, English KA, Pearson TA, Gorham JD
J Immunol. 2009
PubMed ID: 19234226
Serum DNase I, soluble Fas/FasL levels and cell surface Fas expression in patients with SLE: a possible explanation for the lack of efficacy of hrDNase I treatment.
Tinazzi E, Puccetti A, Gerli R, Rigo A, Migliorini P, Simeoni S, Beri R, Dolcino M, Martinelli N, Corrocher R, Lunardi C
Int Immunol. 2009
PubMed ID: 19181929
FAS promoter polymorphisms and cancer risk: a meta-analysis based on 34 case-control studies.
Zhang Z, Xue H, Gong W, Wang M, Yuan L, Han S, Zhang Z
Carcinogenesis. 2009
PubMed ID: 19168581
Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure.
Okada H, Takemura G, Kosai K, Tsujimoto A, Esaki M, Takahashi T, Nagano S, Kanamori H, Miyata S, Li Y, Ohno T, Maruyama R, Ogino A, Li L, Nakagawa M, Nagashima K, Fujiwara T, Fujiwara H, Minatoguchi S
Am J Physiol Heart Circ Physiol. 2009
PubMed ID: 19151252
Intragraft mRNA cytotoxic molecule expression in renal allograft recipients.
Carstens J, Ozbay A, Tørring C, Hansen HE
Transpl Immunol. 2009
PubMed ID: 19141320
Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly.
Engedal N, Auberger P, Blomhoff HK
J Leukoc Biol. 2009
PubMed ID: 19112091
PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15.
Peacock JW, Palmer J, Fink D, Ip S, Pietras EM, Mui AL, Chung SW, Gleave ME, Cox ME, Parsons R, Peter ME, Ong CJ
Mol Cell Biol. 2009
PubMed ID: 19103758
IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice.
Edgerton C, Crispín JC, Moratz CM, Bettelli E, Oukka M, Simovic M, Zacharia A, Egan R, Chen J, Dalle Lucca JJ, Juang YT, Tsokos GC
Clin Immunol. 2009
PubMed ID: 19058762
Thrombin-induced regulation of CD95(Fas) expression in the N9 microglial cell line: evidence for involvement of proteinase-activated receptor(1) and extracellular signal-regulated kinase 1/2.
Weinstein JR, Zhang M, Kutlubaev M, Lee R, Bishop C, Andersen H, Hanisch UK, Möller T
Neurochem Res. 2009
PubMed ID: 18686031
A common hereditary single nucleotide polymorphism in the gene of FAS and colorectal cancer survival.
Hofmann G, Langsenlehner U, Langsenlehner T, Yazdani-Biuki B, Clar H, Gerger A, Fuerst F, Samonigg H, Krippl P, Renner W
J Cell Mol Med. 2009
PubMed ID: 19298528
The many roles of FAS receptor signaling in the immune system.
Strasser A, Jost PJ, Nagata S
Immunity. 2009
PubMed ID: 19239902
The Fas-FADD death domain complex structure unravels signalling by receptor clustering.
Scott FL, Stec B, Pop C, Dobaczewska MK, Lee JJ, Monosov E, Robinson H, Salvesen GS, Schwarzenbacher R, Riedl SJ
Nature. 2009
PubMed ID: 19118384
Depression is an early disease manifestation in lupus-prone MRL/lpr mice.
Gao HX, Campbell SR, Cui MH, Zong P, Hee-Hwang J, Gulinello M, Putterman C
J Neuroimmunol. 2009
PubMed ID: 19121871
[Prognostic role of apoptosis-related gene Fas-1377 and -670 polymorphisms in breast cancer]
Hu Y, Xu Y, Wang Y, Ouyang T, Li JF, Wang TF, Fan ZQ, Fan T, Lin BY, Geng PL, Xie YT
Zhonghua Zhong Liu Za Zhi. 2009
PubMed ID: 19538884
[Effect of fluorouracil combined with FK228 on the proliferation, apoptosis and Fas mRNA level in HepG2 hepatoma cell lines].
Chen Z, Xu K
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009
PubMed ID: 19270351
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis.
Strauss L, Bergmann C, Whiteside TL
J Immunol. 2009
PubMed ID: 19155494
Conformational flexibility of metazoan fatty acid synthase enables catalysis.
Brignole EJ, Smith S, Asturias FJ
Nat Struct Mol Biol. 2009
PubMed ID: 19151726
Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.
Velez DR, Fortunato S, Thorsen P, Lombardi SJ, Williams SM, Menon R
Am J Obstet Gynecol. 2009
PubMed ID: 19019335
Residual CD95-pathway function in children with autoimmune lymphoproliferative syndrome is independent from clinical state and genotype of CD95 mutation.
Fuchs H, Posovszky C, Lahr G, van der Werff ten Bosch J, Boehler T, Debatin KM
Pediatr Res. 2009
PubMed ID: 18948840
Soluble Fas and gonadal hormones in infertile men with varicocele.
Zedan H, El-Mekhlafi AW, El-Noweihi AM, Abd El-Azim NE, Mostafa T
Fertil Steril. 2009
PubMed ID: 18439588
A possible role of Fas-ligand-mediated "reverse signaling" in pathogenesis of rheumatoid arthritis and systemic lupus erythematosus.
Telegina E, Reshetnyak T, Moshnikova A, Proussakova O, Zhukova A, Kuznetsova A, Ivanov A, Paltsev M, Beletsky I
Immunol Lett. 2009
PubMed ID: 19010354
Fas and FasL gene polymorphisms are not associated with cervical cancer but differ among Black and Mixed-ancestry South Africans.
Chatterjee K, Engelmark M, Gyllensten U, Dandara C, van der Merwe L, Galal U, Hoffman M, Williamson AL
BMC Res Notes. 2009
PubMed ID: 19941645
Fas-induced apoptosis of renal cell carcinoma is mediated by apoptosis signal-regulating kinase 1 via mitochondrial damage-dependent caspase-8 activation.
Hassan M, Feyen O, Grinstein E
Cell Oncol. 2009
PubMed ID: 19940360
Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway.
Rajaram MV, Butchar JP, Parsa KV, Cremer TJ, Amer A, Schlesinger LS, Tridandapani S
PLoS One. 2009
PubMed ID: 19936232
Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation.
Huang G, Koshkina NV, Kleinerman ES
Oncol Res. 2009
PubMed ID: 19911702
Serum levels of soluble fas in patients with multinodular goiter.
Andrikoula M, Kolaitis N, Vartholomatos G, Tsatsoulis A
Immunol Invest. 2009
PubMed ID: 19811416
Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy.
Dace DS, Khan AA, Stark JL, Kelly J, Cross AH, Apte RS
PLoS One. 2009
PubMed ID: 19771172
Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus erythematosus.
Hale MB, Krutzik PO, Samra SS, Crane JM, Nolan GP
PLoS One. 2009
PubMed ID: 19707593
Expression of the Bcl-2 protein BAD promotes prostate cancer growth.
Smith AJ, Karpova Y, D'Agostino R, Willingham M, Kulik G
PLoS One. 2009
PubMed ID: 19593445
Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children.
Kotłowska-Kmieć A, Bakowska A, Szarszewski A, Kamińska B, Łuczak G, Radys W, Landowski P, Brodzicki J, Korzon M, Liberek A
Acta Biochim Pol. 2009
PubMed ID: 19572057
[Association between Fas/Fas L genes promoter polymorphisms and pathogenic risk of cervical cancer]
Li H, Guo HY, Sun T, Zhou YF, Lin DX, Zhang WH, Qiao J
Zhonghua Zhong Liu Za Zhi. 2009
PubMed ID: 19538867
If Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.
Menon R, Pearce B, Velez DR, Merialdi M, Williams SM, Fortunato SJ, Thorsen P
Reprod Biol Endocrinol. 2009
PubMed ID: 19527514
Fas/CD95 promoter polymorphism gene and its relationship with cervical carcinoma.
Zucchi F, da Silva ID, Ribalta JC, de Souza NC, Speck NM, Girão MJ, Brenna SM, Syrjänen KJ
Eur J Gynaecol Oncol. 2009
PubMed ID: 19480241
Expressions of Fas/DcR3 and RGD-FasL mediated apoptosis in pituitary adenomas.
Chen L, Tian X, Li W, Agarwal A, Zhuang G
Neurol India. 2009
PubMed ID: 19305072
[Effect of aluminium on neural behavior and the expression of Bcl-2 and Fas in hippocampus of weaning rats].
Jin C, Liu Q, Wang J, Cai Y
Wei Sheng Yan Jiu. 2009
PubMed ID: 19267062
The role of MMP7 and its cross-talk with the FAS/FASL system during the acquisition of chemoresistance to oxaliplatin.
Almendro V, Ametller E, García-Recio S, Collazo O, Casas I, Augé JM, Maurel J, Gascón P
PLoS One. 2009
PubMed ID: 19266094
Immunohistochemical analysis of Fas and FLIP in prostate cancers.
Kim SY, Song SY, Kim MS, Lee JY, Lee HM, Choi HY, Yoo NJ, Lee SH
APMIS. 2009
PubMed ID: 19161534
FAS and FASLG polymorphisms and susceptibility to idiopathic azoospermia or severe oligozoospermia.
Wang W, Lu N, Xia Y, Gu A, Wu B, Liang J, Zhang W, Wang Z, Su J, Wang X
Reprod Biomed Online. 2009
PubMed ID: 19146781
The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity. 2009
PubMed ID: 19144319
Mitochondria influence Fas expression in gp120-induced apoptosis of neuronal cells.
Thomas S, Mayer L, Sperber K
Int J Neurosci. 2009
PubMed ID: 19125371
Involvement of mitochondrial signaling pathways in the mechanism of Fas-mediated apoptosis after spinal cord injury.
Yu WR, Liu T, Fehlings TK, Fehlings MG
Eur J Neurosci. 2009
PubMed ID: 19120440
The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin.
Aprahamian T, Bonegio RG, Richez C, Yasuda K, Chiang LK, Sato K, Walsh K, Rifkin IR
J Immunol. 2009
PubMed ID: 19109165
Reduced FAS transcription in clones of U937 cells that have acquired resistance to Fas-induced apoptosis.
Blomberg J, Ruuth K, Jacobsson M, Höglund A, Nilsson JA, Lundgren E
FEBS J. 2009
PubMed ID: 19076218
Fas death receptor enhances endocytic membrane traffic converging into the Golgi region.
Degli Esposti M, Tour J, Ouasti S, Ivanova S, Matarrese P, Malorni W, Khosravi-Far R
Mol Biol Cell. 2009
PubMed ID: 19037097
Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes: therapeutic implications for hepatitis C.
Wedemeyer I, Bechmann LP, Odenthal M, Jochum C, Marquitan G, Drebber U, Gerken G, Gieseler RK, Dienes HP, Canbay A
J Hepatol. 2009
PubMed ID: 19019483
Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer.
Wang SS, Bratti MC, Rodríguez AC, Herrero R, Burk RD, Porras C, González P, Sherman ME, Wacholder S, Lan ZE, Schiffman M, Chanock SJ, Hildesheim A
J Infect Dis. 2009
PubMed ID: 19012493
SBDS-deficiency results in specific hypersensitivity to Fas stimulation and accumulation of Fas at the plasma membrane.
Watanabe K, Ambekar C, Wang H, Ciccolini A, Schimmer AD, Dror Y
Apoptosis. 2009
PubMed ID: 19009351
EGF and HGF levels are increased during active HBV infection and enhance survival signaling through extracellular matrix interactions in primary human hepatocytes.
Barreiros AP, Sprinzl M, Rosset S, Höhler T, Otto G, Theobald M, Galle PR, Strand D, Strand S
Int J Cancer. 2009
PubMed ID: 18844210
Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.
Woodworth JS, Wu Y, Behar SM
J Immunol. 2008
PubMed ID: 19050279
West Nile virus-specific CD4 T cells exhibit direct antiviral cytokine secretion and cytotoxicity and are sufficient for antiviral protection.
Brien JD, Uhrlaub JL, Nikolich-Zugich J
J Immunol. 2008
PubMed ID: 19050276
[Expression of Fas protein in myocardiac tissue of viral myocarditis and dilated cardiomyopathy]
Wu XQ, Li YH, Zhu X, Wu MW, Hu SM
Fa Yi Xue Za Zhi. 2008
PubMed ID: 19241965
FAS promoter polymorphism: outcome of childhood acute myeloid leukemia. A children's oncology group report.
Mehta PA, Gerbing RB, Alonzo TA, Elliott JS, Zamzow TA, Combs M, Stover E, Ross JA, Perentesis JP, Meschinchi S, Lange BJ, Davies SM
Clin Cancer Res. 2008
PubMed ID: 19047119
The expressions of Fas and caspase-3 in human glaucomatous optic nerve axons.
Zalewska R, Zalewski B, Reszec J, Mariak Z, Zimnoch L, Proniewska-Skretek E
Med Sci Monit. 2008
PubMed ID: 19043361
Granzyme C supports efficient CTL-mediated killing late in primary alloimmune responses.
Getachew Y, Stout-Delgado H, Miller BC, Thiele DL
J Immunol. 2008
PubMed ID: 19017970
Cutting edge: migration of langerhans dendritic cells is impaired in autoimmune dermatitis.
Eriksson AU, Singh RR
J Immunol. 2008
PubMed ID: 19017935
Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.
Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ
Eur J Immunol. 2008
PubMed ID: 19009528
Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes.
Walter D, Schmich K, Vogel S, Pick R, Kaufmann T, Hochmuth FC, Haber A, Neubert K, McNelly S, von Weizsäcker F, Merfort I, Maurer U, Strasser A, Borner C
Hepatology. 2008
PubMed ID: 19003879
Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss.
Gilbert S, Ruel A, Loranger A, Marceau N
Apoptosis. 2008
PubMed ID: 19002587
Hepatocellular apoptosis is mediated by TNFalpha-dependent Fas/FasLigand cytotoxicity in a murine model of acute liver failure.
Kuhla A, Eipel C, Siebert N, Abshagen K, Menger MD, Vollmar B
Apoptosis. 2008
PubMed ID: 18946736
c-Jun N-terminal kinases mediate Fas-induced neurite regeneration in PC12 cells.
Waetzig V, Loose K, Haeusgen W, Herdegen T
Biochem Pharmacol. 2008
PubMed ID: 18692025
The extracellular glycosphingolipid-binding motif of Fas defines its internalization route, mode and outcome of signals upon activation by ligand.
Chakrabandhu K, Huault S, Garmy N, Fantini J, Stebe E, Mailfert S, Marguet D, Hueber AO
Cell Death Differ. 2008
PubMed ID: 18670435
The Fas system confers protection against alveolar disruption in hyperoxia-exposed newborn mice.
Mao Q, Gundavarapu S, Patel C, Tsai A, Luks FI, De Paepe ME
Am J Respir Cell Mol Biol. 2008
PubMed ID: 18587053
B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency.
Gupta VA, Hermiston ML, Cassafer G, Daikh DI, Weiss A
J Exp Med. 2008
PubMed ID: 19001138
Dissection of effector pathways in the host-versus-graft response to bone marrow transplantation.
Weng L, Addey C, Warrens AN, Dyson J, Chai JG, Dazzi F
Transplantation. 2008
PubMed ID: 19005414
Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice.
Menke J, Hsu MY, Byrne KT, Lucas JA, Rabacal WA, Croker BP, Zong XH, Stanley ER, Kelley VR
J Immunol. 2008
PubMed ID: 18981160
[The change of certain biochemical indexes and apotosis protein (Fas/FasL) expression in rat liver of selenium and iodine deficiency].
Zhang D, Lei Y, Zhao J, Tan W
Wei Sheng Yan Jiu. 2008
PubMed ID: 19239001
Leptin regulates the proliferation and apoptosis of human endometrial epithelial cells.
Tanaka T, Umesaki N
Int J Mol Med. 2008
PubMed ID: 18949391
Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses.
Puliaeva I, Puliaev R, Shustov A, Haas M, Via CS
J Immunol. 2008
PubMed ID: 18941180
Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.
Wu X, Lu C, Ye Y, Chang J, Yang H, Lin J, Gu J, Hong WK, Stewart D, Spitz MR
Pharmacogenet Genomics. 2008
PubMed ID: 18854777
c-FLIP protects mature T lymphocytes from TCR-mediated killing.
Zhang N, Hopkins K, He YW
J Immunol. 2008
PubMed ID: 18832693
Brief cross-linking of Fas/APO-1 (CD95) triggers engulfment of pre-apoptotic target cells.
Zhang S, Witasp E, Lauwen M, Fadeel B
FEBS Lett. 2008
PubMed ID: 18804468
RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition.
Bonnal S, Martínez C, Förch P, Bachi A, Wilm M, Valcárcel J
Mol Cell. 2008
PubMed ID: 18851835
[Expressions of Fas, CTLA-4 and RhoBTB2 genes in breast carcinoma and their relationship with clinicopathological factors]
Bi Y, Wei L, Mao HT, Zhang L, Zuo WS
Zhonghua Zhong Liu Za Zhi. 2008
PubMed ID: 19173804
No association between Fas A/G polymorphism and therapeutic effects induced by methimazole treatment for Graves' disease in Northern Chinese.
Li P, Li Q, Chen L, Sun Y, Zhang J
Pharmazie. 2008
PubMed ID: 18972838
Differential role of the transcription factor NF-kappaB in selection and survival of CD4+ and CD8+ thymocytes.
Jimi E, Strickland I, Voll RE, Long M, Ghosh S
Immunity. 2008
PubMed ID: 18957265
Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis.
Hao Z, Duncan GS, Seagal J, Su YW, Hong C, Haight J, Chen NJ, Elia A, Wakeham A, Li WY, Liepa J, Wood GA, Casola S, Rajewsky K, Mak TW
Immunity. 2008
PubMed ID: 18835195
Evaluation of apoptotic cells and immunohistochemical detection of FAS, FAS-L, Bcl-2, Bax, p53 and c-Myc in the skin of patients with chronic venous leg ulcers.
Heising S, Giebel J, Ostrowitzki AL, Riedel F, Haase H, Sippel K, Jünger M
Int J Mol Med. 2008
PubMed ID: 18813857
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.
Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, Spiegel S, Norris J, Fisher PB, Grant S, Dent P
Cancer Biol Ther. 2008
PubMed ID: 18787411
A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis.
Bradshaw S, Zheng WJ, Tsoi LC, Gilkeson G, Zhang XK
Clin Immunol. 2008
PubMed ID: 18692443
Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen.
Alabyev B, Vuyyuru R, Manser T
Int Immunol. 2008
PubMed ID: 18689725
Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice.
Zhang MC, Furukawa H, Tokunaka K, Saiga K, Date F, Owada Y, Nose M, Ono M
Immunogenetics. 2008
PubMed ID: 18677469
In vivo 5-fluorouracil-[corrected]induced apoptosis on murine thymocytes: involvement of FAS, Bax and Caspase3.
Aquino Esperanza JA, Aguirre MV, Aispuru GR, Lettieri CN, Juaristi JA, Alvarez MA, Brandan NC
Cell Biol Toxicol. 2008
PubMed ID: 18266059
CD95 stimulation results in the formation of a novel death effector domain protein-containing complex.
Lavrik IN, Mock T, Golks A, Hoffmann JC, Baumann S, Krammer PH
J Biol Chem. 2008
PubMed ID: 18635548
Functional genetic screening reveals the role of mitochondrial cytochrome b as a mediator of FAS-induced apoptosis.
Komarov AP, Rokhlin OW, Yu CA, Gudkov AV
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18796602
Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy.
Zanone Poma B, Riva A, Nasi M, Cicconi P, Broggini V, Lepri AC, Mologni D, Mazzotta F, Monforte AD, Mussini C, Cossarizza A, Galli M, Icona Foundation Study Group
AIDS. 2008
PubMed ID: 18753860
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, Dent P
J Biol Chem. 2008
PubMed ID: 18614532
[CMV-induced cell death and fas gene expression in resting and proliferating human fibroblasts]
Fedorova NE, Sokolova TM, Medzhidova MG, Uryvaev LV, Kushch AA
Zh Mikrobiol Epidemiol Immunobiol. 2008
PubMed ID: 19004284
Death receptor Fas (CD95) signaling in the central nervous system: tuning neuroplasticity?
Reich A, Spering C, Schulz JB
Trends Neurosci. 2008
PubMed ID: 18676032
Neutrophil-dependent tumor rejection and priming of tumoricidal CD8+ T cell response induced by dendritic cells overexpressing CD95L.
Buonocore S, Haddou NO, Moore F, Florquin S, Paulart F, Heirman C, Thielemans K, Goldman M, Flamand V
J Leukoc Biol. 2008
PubMed ID: 18567840
Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis.
Lalli PN, Strainic MG, Yang M, Lin F, Medof ME, Heeger PS
Blood. 2008
PubMed ID: 18567839
Fas-mediated T cell deletion potentiates tumor antigen-specific tolerance in a mouse model of prostate cancer.
Tseng-Rogenski SS, Arredouani MS, Neeley YC, Lu B, Chinnaiyan AM, Sanda MG
Cancer Immunol Immunother. 2008
PubMed ID: 18265979
Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer.
Ter-Minassian M, Zhai R, Asomaning K, Su L, Zhou W, Liu G, Heist RS, Lynch TJ, Wain JC, Lin X, Devivo I, Christiani DC
Carcinogenesis. 2008
PubMed ID: 18757527
Programmed death ligand 1 regulates a critical checkpoint for autoimmune myocarditis and pneumonitis in MRL mice.
Lucas JA, Menke J, Rabacal WA, Schoen FJ, Sharpe AH, Kelley VR
J Immunol. 2008
PubMed ID: 18684942
High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95.
Troeger A, Glouchkova L, Ackermann B, Escherich G, Meisel R, Hanenberg H, den Boer ML, Pieters R, Janka-Schaub GE, Goebel U, Laws HJ, Dilloo D
Blood. 2008
PubMed ID: 18552209
Priming of T cells to Fas-mediated proliferative signals by interleukin-7.
Rethi B, Vivar N, Sammicheli S, Fluur C, Ruffin N, Atlas A, Rajnavolgyi E, Chiodi F
Blood. 2008
PubMed ID: 18441236
Expression levels of FAS are regulated through an evolutionary conserved element in intron 2, which modulates cystic fibrosis disease severity.
Kumar V, Becker T, Jansen S, van Barneveld A, Boztug K, Wölfl S, Tümmler B, Stanke F
Genes Immun. 2008
PubMed ID: 18685642
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Autoregulation of Th1-mediated inflammation by twist1.
Niesner U, Albrecht I, Janke M, Doebis C, Loddenkemper C, Lexberg MH, Eulenburg K, Kreher S, Koeck J, Baumgrass R, Bonhagen K, Kamradt T, Enghard P, Humrich JY, Rutz S, Schulze-Topphoff U, Aktas O, Bartfeld S, Radbruch H, Hegazy AN, Löhning M, Baumgart DC, Duchmann R, Rudwaleit M, Häupl T, Gitelman I, Krenn V, Gruen J, Sieper J, Zeitz M, Wiedenmann B, Zipp F, Hamann A, Janitz M, Scheffold A, Burmester GR, Chang HD, Radbruch A
J Exp Med. 2008
PubMed ID: 18663125
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.
Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders HJ
J Exp Med. 2008
PubMed ID: 18644972
[Relationships of serum selenium, VEGF and sFas levels in leukemia patients]
Wang Y, Liu FQ, Wu YP
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008
PubMed ID: 18718055
T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells.
Herlands RA, Christensen SR, Sweet RA, Hershberg U, Shlomchik MJ
Immunity. 2008
PubMed ID: 18691914
Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via Fas.
de Giorgio R, Volta U, Stanghellini V, Cogliandro RF, Barbara G, Corinaldesi R, Towns R, Guo C, Hong S, Wiley JW
Gastroenterology. 2008
PubMed ID: 18582468
Elevated Fas expression is related to increased apoptosis of circulating CD8+ T cell in patients with gastric cancer.
Yoshikawa T, Saito H, Osaki T, Matsumoto S, Tsujitani S, Ikeguchi M
J Surg Res. 2008
PubMed ID: 18561948
Blockade of the Fas/Fas ligand interaction suppresses hepatocyte apoptosis in ischemia-reperfusion rat liver.
Nakajima H, Mizuta N, Fujiwara I, Sakaguchi K, Ogata H, Magae J, Yagita H, Koji T
Apoptosis. 2008
PubMed ID: 18561025
A novel juxtamembrane domain in tumor necrosis factor receptor superfamily molecules activates Rac1 and controls neurite growth.
Ruan W, Lee CT, Desbarats J
Mol Biol Cell. 2008
PubMed ID: 18508927
Fas splicing regulation during early apoptosis is linked to caspase-mediated cleavage of U2AF65.
Izquierdo JM
Mol Biol Cell. 2008
PubMed ID: 18508922
Accumulation of bis(monoacylglycero)phosphate and gangliosides in mouse models of neuronal ceroid lipofuscinosis.
Jabs S, Quitsch A, Käkelä R, Koch B, Tyynelä J, Brade H, Glatzel M, Walkley S, Saftig P, Vanier MT, Braulke T
J Neurochem. 2008
PubMed ID: 18498441
Genetic Polymorphisms of IL-1A, IL-1B, IL-1RN, NFKB1, FAS, and FASL, and Risk of Silicosis in a Chinese Occupational Population.
Wu F, Xia Z, Qu Y, Tang Y, Cao D, Sun P, Christiani DC
Am J Ind Med. 2008
PubMed ID: 18666137
Hu antigen R (HuR) functions as an alternative pre-mRNA splicing regulator of Fas apoptosis-promoting receptor on exon definition.
Izquierdo JM
J Biol Chem. 2008
PubMed ID: 18463097
Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas.
Bonzheim I, Geissinger E, Chuang WY, Roth S, Ströbel P, Marx A, Reimer P, Wilhelm M, Puppe B, Rosenwald A, Müller-Hermelink HK, Rüdiger T
J Hematop. 2008
PubMed ID: 19669200
Immunohistochemical expression of fatty acid synthase, Ki-67 and p53 in squamous cell carcinomas of the larynx.
De Vincentiis M, Di Cello P, Censi F, Leopizzi M, Natalizi S, Sardella B, Gallo A, Soldo P, Alò PL, Zotti GC, Della Rocca C, Pietrasanta D, Castelli M, Izzo L
Int J Biol Markers. 2008
PubMed ID: 18949744
Fas promoter polymorphisms: genetic predisposition to sarcoidosis in African-Americans.
Wasfi YS, Silveira LJ, Jonth A, Hokanson JE, Fingerlin T, Sato H, Parsons CE, Lympany P, Welsh K, du Bois RM, Newman LS, Maier LA, ACCESS Research Group
Tissue Antigens. 2008
PubMed ID: 18588573
Protective role of interleukin-18 against Fas-mediated liver injury.
Yamamoto N, Murata K, Yoneda K, Fuke H, Yamaguchi Y, Ito K, Sugimoto K, Shiraki K, Yamanaka K, Mizutani H, Takei Y
Int J Mol Med. 2008
PubMed ID: 18575774
Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-gamma.
Zhang Y, Xu G, Zhang L, Roberts AI, Shi Y
J Immunol. 2008
PubMed ID: 18566384
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis.
Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, Wiethe C, Winkler TH, Kalden JR, Manz RA, Voll RE
Nat Med. 2008
PubMed ID: 18542049
Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice.
Kobayashi T, Takahashi K, Nagai Y, Shibata T, Otani M, Izui S, Akira S, Gotoh Y, Kiyono H, Miyake K
Int Immunol. 2008
PubMed ID: 18492657
Fas/FasL-dependent apoptosis of hepatocytes induced in rat and patients with Clonorchis sinensis infection.
Zhang X, Jin Z, Da R, Dong Y, Song W, Chen X, Huang Q, Ling H, Che Y, Li Y, Zhang F
Parasitol Res. 2008
PubMed ID: 18427836
Differential roles of ICAM-1 and VCAM-1 in leukocyte-endothelial cell interactions in skin and brain of MRL/faslpr mice.
Norman MU, James WG, Hickey MJ
J Leukoc Biol. 2008
PubMed ID: 18426970
Placental fas/fas ligand expression in early pregnancy losses.
Guvendag Guven ES, Okur H, Beksac MS
Am J Reprod Immunol. 2008
PubMed ID: 18422813
Fas/CD95-mediated apoptosis of type II cells is blocked by Toxoplasma gondii primarily via interference with the mitochondrial amplification loop.
Hippe D, Lytovchenko O, Schmitz I, Lüder CG
Infect Immun. 2008
PubMed ID: 18411295
FasL shedding is reduced by hypothermia in experimental stroke.
Liu L, Kim JY, Koike MA, Yoon YJ, Tang XN, Ma H, Lee H, Steinberg GK, Lee JE, Yenari MA
J Neurochem. 2008
PubMed ID: 18410517
Oocytes in newborn MRL mouse testes.
Otsuka S, Konno A, Hashimoto Y, Sasaki N, Endoh D, Kon Y
Biol Reprod. 2008
PubMed ID: 18354036
In vivo responses to vaccination with Mage-b, GM-CSF and thioglycollate in a highly metastatic mouse breast tumor model, 4T1.
Gravekamp C, Leal B, Denny A, Bahar R, Lampkin S, Castro F, Kim SH, Moore D, Reddick R
Cancer Immunol Immunother. 2008
PubMed ID: 18094967
Vascular endothelial growth factor reduces Fas-mediated acute liver injury in mice.
Tanaka Y, Sohda T, Matsuo K, Anan A, Irie M, Takeyama Y, Iwata K, Shakado S, Sakisaka S
J Gastroenterol Hepatol. 2008
PubMed ID: 17784864
Transient local depletion of Foxp3(+) regulatory T cells during recovery from colitis via Fas/Fas ligand-induced death.
Reardon C, Wang A, McKay DM
J Immunol. 2008
PubMed ID: 18523298
New approach reveals CD28 and IFNG gene interaction in the susceptibility to cervical cancer.
Guzman VB, Yambartsev A, Goncalves-Primo A, Silva ID, Carvalho CR, Ribalta JC, Goulart LR, Shulzhenko N, Gerbase-Delima M, Morgun A
Hum Mol Genet. 2008
PubMed ID: 18337305
Functional Polymorphisms of the FAS Gene Associated with Risk of Vitiligo in Chinese Populations: A Case-Control Analysis.
Li M, Sun D, Li C, Zhang Z, Gao L, Li K, Li H, Gao T
J Invest Dermatol. 2008
PubMed ID: 18548110
[Apoptosis of active T lymphocytes induced by human laryngocarcinoma cell line].
Ye J, Zhang G, Liu X, Yang Q, Li P, Huang J, Li Y
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008
PubMed ID: 18800686
Utility of antiPax5 in the diagnosis of lymphoproliferative disorders and neoplasia in mice.
Rehg JE, Sundberg JP
Comp Med. 2008
PubMed ID: 18589866
Effect of retinoic acid on apoptosis and expression of Fas proteins in mouse blastocysts cultured in vitro.
Xiong Y, Zhang D
J Huazhong Univ Sci Technolog Med Sci. 2008
PubMed ID: 18563314
Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95.
Jacobi AM, Reiter K, Mackay M, Aranow C, Hiepe F, Radbruch A, Hansen A, Burmester GR, Diamond B, Lipsky PE, Dörner T
Arthritis Rheum. 2008
PubMed ID: 18512812
Differential expression of Fas system apoptotic molecules in peripheral lymphocytes from patients with Graves' disease and Hashimoto's thyroiditis.
Fountoulakis S, Vartholomatos G, Kolaitis N, Frillingos S, Philippou G, Tsatsoulis A
Eur J Endocrinol. 2008
PubMed ID: 18505906
Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15.
Yang CH, Tian L, Ling GS, Trendell-Smith NJ, Ma L, Lo CK, Stott DI, Liew FY, Huang FP
Eur J Immunol. 2008
PubMed ID: 18465774
The hepatic vagus nerve attenuates Fas-induced apoptosis in the mouse liver via alpha7 nicotinic acetylcholine receptor.
Hiramoto T, Chida Y, Sonoda J, Yoshihara K, Sudo N, Kubo C
Gastroenterology. 2008
PubMed ID: 18439427
Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity.
Abe Y, Yoshikawa T, Kamada H, Shibata H, Nomura T, Minowa K, Kayamuro H, Katayama K, Miyoshi H, Mukai Y, Yoshioka Y, Nakagawa S, Tsunoda S, Tsutsumi Y
J Immunol Methods. 2008
PubMed ID: 18417150
p53-dependent apoptosis in the inhibition of spermatogonial differentiation in juvenile spermatogonial depletion (Utp14bjsd) mice.
Shetty G, Shao SH, Weng CC
Endocrinology. 2008
PubMed ID: 18356279
Hepatocyte-specific c-Met deletion disrupts redox homeostasis and sensitizes to Fas-mediated apoptosis.
Gómez-Quiroz LE, Factor VM, Kaposi-Novak P, Coulouarn C, Conner EA, Thorgeirsson SS
J Biol Chem. 2008
PubMed ID: 18348981
A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA.
Masuda K, Teshima-Kondo S, Mukaijo M, Yamagishi N, Nishikawa Y, Nishida K, Kawai T, Rokutan K
PLoS Med. 2008
PubMed ID: 18494554
Functional variants in cell death pathway genes and risk of pancreatic cancer.
Yang M, Sun T, Wang L, Yu D, Zhang X, Miao X, Liu J, Zhao D, Li H, Tan W, Lin D
Clin Cancer Res. 2008
PubMed ID: 18483392
Stabilized beta-catenin potentiates Fas-mediated T cell apoptosis.
Huang Z, Wang R, Xie H, Shang W, Manicassamy S, Sun Z
J Immunol. 2008
PubMed ID: 18453577
Relationship between expression of gastrin, somatostatin, Fas/FasL and caspases in large intestinal carcinoma.
Mao JD, Wu P, Yang YL, Wu J, Huang H
World J Gastroenterol. 2008
PubMed ID: 18473402
[Fas-FasL and caspase-3 signal transduction pathway and apoptosis of peripheral T lymphocytes in ITP patients]
Zhong YG, Feng WY, Luo HQ, Fu JP, Jin J
Zhonghua Xue Ye Xue Za Zhi. 2008
PubMed ID: 18844072
High serum levels of soluble Fas (sFas) in CKD patients: effects of renal clearance, reabsorption and synthesis.
Dalboni MA, Cenedeze MA, Manfredi SR, Cruz Andreoli MC, Pavao Dos Santos O, Canziani ME, Boim MA, Goes MA, Draibe SA, Balakrishnan V, Cendoroglo M
Int J Artif Organs. 2008
PubMed ID: 18609513
Accelerated atherosclerosis in ApoE deficient lupus mouse models.
Ma Z, Choudhury A, Kang SA, Monestier M, Cohen PL, Eisenberg RA
Clin Immunol. 2008
PubMed ID: 18325838
Coelomic cells show apoptosis via Fas/FasL system: a comparative study between healthy human pregnancies and missed miscarriages.
Kaponis A, Skyrlas A, Zagorianakou N, Georgiou I, Passa V, Paraskevaidis E, Makrydimas G
Hum Reprod. 2008
PubMed ID: 18316328
The death ligand TRAIL in diabetic nephropathy.
Lorz C, Benito-Martín A, Boucherot A, Ucero AC, Rastaldi MP, Henger A, Armelloni S, Santamaría B, Berthier CC, Kretzler M, Egido J, Ortiz A
J Am Soc Nephrol. 2008
PubMed ID: 18287563
CSF levels of soluble HLA-G and Fas molecules are inversely associated to MRI evidence of disease activity in patients with relapsing-remitting multiple sclerosis.
Fainardi E, Rizzo R, Melchiorri L, Stignani M, Castellazzi M, Tamborino C, Paolino E, Tola MR, Granieri E, Baricordi OR
Mult Scler. 2008
PubMed ID: 18208868
The -670G>A polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis.
Liakouli V, Manetti M, Pacini A, Tolusso B, Fatini C, Toscano A, Cipriani P, Guiducci S, Bazzichi L, Codullo V, Ruocco L, Dell'orso L, Carubbi F, Marrelli A, Abbate R, Bombardieri S, Ferraccioli G, Montecucco C, Valentini G, Matucci-Cerinic M, Ibba-Manneschi L, Giacomelli R
Ann Rheum Dis. 2008
PubMed ID: 18445624
CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells.
Llobet D, Eritja N, Encinas M, Llecha N, Yeramian A, Pallares J, Sorolla A, Gonzalez-Tallada FJ, Matias-Guiu X, Dolcet X
Oncogene. 2008
PubMed ID: 17982483
Dynamic changes of IL-2/IL-10, sFas and expression of Fas in intestinal mucosa in rats with acute necrotizing pancreatitis.
Dang SC, Zhang JX, Qu JG, Mao ZF, Wang XQ, Zhu B
World J Gastroenterol. 2008
PubMed ID: 18407603
Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb.
Brownlie RJ, Lawlor KE, Niederer HA, Cutler AJ, Xiang Z, Clatworthy MR, Floto RA, Greaves DR, Lyons PA, Smith KG
J Exp Med. 2008
PubMed ID: 18362174
Anti-fas activating antibody enhances trophoblast outgrowth on endometrial epithelial cells by induction of P38 MAPK/JNK-mediated apoptosis.
Hsu WL, Chen YH, Chao KC, Chang SP, Tsui KH, Li HY, Sung YJ
Placenta. 2008
PubMed ID: 18342935
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Stimulation of inducible nitric oxide synthase expression by beta interferon increases necrotic death of macrophages upon Listeria monocytogenes infection.
Zwaferink H, Stockinger S, Reipert S, Decker T
Infect Immun. 2008
PubMed ID: 18268032
Streptococcal pyrogenic exotoxin B-induced apoptosis in A549 cells is mediated through alpha(v)beta(3) integrin and Fas.
Tsai WH, Chang CW, Lin YS, Chuang WJ, Wu JJ, Liu CC, Tsai PJ, Lin MT
Infect Immun. 2008
PubMed ID: 18227168
Caspase activation in fetal rat brain following experimental intrauterine inflammation.
Sharangpani A, Takanohashi A, Bell MJ
Brain Res. 2008
PubMed ID: 18289516
Yes and PI3K bind CD95 to signal invasion of glioblastoma.
Kleber S, Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, Schreglmann N, Letellier E, Zuliani C, Klussmann S, Teodorczyk M, Gröne HJ, Ganten TM, Sültmann H, Tüttenberg J, von Deimling A, Regnier-Vigouroux A, Herold-Mende C, Martin-Villalba A
Cancer Cell. 2008
PubMed ID: 18328427
Identification of apoptotic proteins in thyroid gland from patients with Graves' disease and Hashimoto's thyroiditis.
Bossowski A, Czarnocka B, Bardadin K, Stasiak-Barmuta A, Urban M, Dadan J, Ratomski K, Bossowska A
Autoimmunity. 2008
PubMed ID: 18324486
Exosomes As a Short-Range Mechanism to Spread Alloantigen between Dendritic Cells during T Cell Allorecognition.
Montecalvo A, Shufesky WJ, Stolz DB, Sullivan MG, Wang Z, Divito SJ, Papworth GD, Watkins SC, Robbins PD, Larregina AT, Morelli AE
J Immunol. 2008
PubMed ID: 18292531
Mutation in the Fas Pathway Impairs CD8+ T Cell Memory.
Dudani R, Russell M, van Faassen H, Krishnan L, Sad S
J Immunol. 2008
PubMed ID: 18292515
Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cells.
Dolfi DV, Boesteanu AC, Petrovas C, Xia D, Butz EA, Katsikis PD
J Immunol. 2008
PubMed ID: 18292513
SBDS-deficient cells undergo accelerated apoptosis through the Fas-pathway.
Rujkijyanont P, Watanabe K, Ambekar C, Wang H, Schimmer A, Beyene J, Dror Y
Haematologica. 2008
PubMed ID: 18268284
Critical role for c-FLIP(L) on Fas resistance in colon carcinoma cell line HT-29.
Zang F, Sun B, Zhao X, Niu R, Zhang S, Yu M, Wei X, Zhang L
Cell Biol Int. 2008
PubMed ID: 18243739
Toward a confocal subcellular atlas of the human proteome.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Mol Cell Proteomics. 2008
PubMed ID: 18029348
Fas single nucleotide polymorphisms and risk of thyroid and salivary gland carcinomas: a case-control analysis.
Ho T, Li G, Zhao C, Zheng R, Wei Q, Sturgis EM
Head Neck. 2008
PubMed ID: 17657791
A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis.
Couzinet A, Tamura K, Chen HM, Nishimura K, Wang Z, Morishita Y, Takeda K, Yagita H, Yanai H, Taniguchi T, Tamura T
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18268344
Semaphorin3A signaling controls Fas (CD95)-mediated apoptosis by promoting Fas translocation into lipid rafts.
Moretti S, Procopio A, Lazzarini R, Rippo MR, Testa R, Marra M, Tamagnone L, Catalano A
Blood. 2008
PubMed ID: 18056484
Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.
Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M
EMBO J. 2008
PubMed ID: 18219273
Evaluation of functional single nucleotide polymorphisms of different genes coding for the immunoregulatory molecules in patients with monoclonal large granular lymphocyte lymphocytosis.
Garrido P, Almeida J, Romero JM, Cantón J, Sandberg Y, Bárcena P, Lima M, Langerak AW, Orfao A, Ruiz-Cabello F
Hum Immunol. 2008
PubMed ID: 18361934
Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction.
Weant AE, Michalek RD, Khan IU, Holbrook BC, Willingham MC, Grayson JM
Immunity. 2008
PubMed ID: 18275832
Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity.
Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK, Wu T, Li QZ, Davis LS, Mohan C, Perlman H
Immunity. 2008
PubMed ID: 18275831
Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.
Hughes PD, Belz GT, Fortner KA, Budd RC, Strasser A, Bouillet P
Immunity. 2008
PubMed ID: 18275830
Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus.
Miyagawa H, Yamai M, Sakaguchi D, Kiyohara C, Tsukamoto H, Kimoto Y, Nakamura T, Lee JH, Tsai CY, Chiang BL, Shimoda T, Harada M, Tahira T, Hayashi K, Horiuchi T
Rheumatology (Oxford). 2008
PubMed ID: 18174230
Conversion of CD95 (Fas) Type II into Type I signaling by sub-lethal doses of cycloheximide.
Brumatti G, Yon M, Castro FA, Bueno-da-Silva AE, Jacysyn JF, Brunner T, Amarante-Mendes GP
Exp Cell Res. 2008
PubMed ID: 18078929
Antigen activation and impaired Fas-induced death-inducing signaling complex formation in T-large-granular lymphocyte leukemia.
Yang J, Epling-Burnette PK, Painter JS, Zou J, Bai F, Wei S, Loughran TP
Blood. 2008
PubMed ID: 17993614
Antiproliferative activity of paeoniflorin is through cell cycle arrest and the Fas/Fas ligand-mediated apoptotic pathway in human non-small cell lung cancer A549 cells.
Hung JY, Yang CJ, Tsai YM, Huang HW, Huang MS
Clin Exp Pharmacol Physiol. 2008
PubMed ID: 17941899
Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes.
Reinehr R, Sommerfeld A, Keitel V, Grether-Beck S, Haüssinger D
J Biol Chem. 2008
PubMed ID: 18045865
ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.
Stagni V, di Bari MG, Cursi S, Condò I, Cencioni MT, Testi R, Lerenthal Y, Cundari E, Barilà D
Blood. 2008
PubMed ID: 17932249
Targeting Notch signaling in autoimmune and lymphoproliferative disease.
Teachey DT, Seif AE, Brown VI, Bruno M, Bunte RM, Chang YJ, Choi JK, Fish JD, Hall J, Reid GS, Ryan T, Sheen C, Zweidler-McKay P, Grupp SA
Blood. 2008
PubMed ID: 17925488
Downregulation of IFN-gammaR in association with loss of Fas function is linked to tumor progression.
Yang D, Stewart TJ, Smith KK, Georgi D, Abrams SI, Liu K
Int J Cancer. 2008
PubMed ID: 17918178
Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.
Mohamood AS, Bargatze D, Xiao Z, Jie C, Yagita H, Ruben D, Watson J, Chakravarti S, Schneck JP, Hamad AR
PLoS ONE. 2008
PubMed ID: 18941614
Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants.
Velez DR, Fortunato SJ, Thorsen P, Lombardi SJ, Williams SM, Menon R
PLoS ONE. 2008
PubMed ID: 18818748
Association of Fas-670 gene polymorphism with risk of cervical cancer in North Indian population.
Tamandani DM, Sobti RC, Shekari M
Clin Exp Obstet Gynecol. 2008
PubMed ID: 18754288
Circulating and hepatic Fas expression in HCV-induced chronic liver disease and hepatocellular carcinoma.
El Bassiouny AE, El-Bassiouni NE, Nosseir MM, Zoheiry MM, El-Ahwany EG, Salah F, Omran ZS, Ibrahim RA
Medscape J Med. 2008
PubMed ID: 18679533
Fas expression in primary breast cancer is related to neoplastic infiltration of perilymphatic fat.
Bebenek M, Duś D, Koźlak J
Adv Med Sci. 2008
PubMed ID: 18614439
Polymorphisms of death pathway genes FAS and FASL and risk of premalignant gastric lesions.
Hsu PI, Lu PJ, Wang EM, Ger LP, Lo GH, Tsay FW, Chen TA, Yang HB, Chen HC, Lin WS, Lai KH
Anticancer Res. 2008
PubMed ID: 18383830
[Polymorphisms of FAS and FASL genes and susceptibility of silicosis]
Wu F, Qu YB, Sun P, Ji F, Qiu YL, Miao WB, Wang W, Jin RF, Xia ZL
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008
PubMed ID: 18302883
Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer.
McDonnell TJ, Chari NS, Cho-Vega JH, Troncoso P, Wang X, Bueso-Ramos CE, Coombes K, Brisbay S, Lopez R, Prendergast G, Logothetis C, Do KA
BMC Med Genomics. 2008
PubMed ID: 18237448
Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.
Chetoui N, Sylla K, Gagnon-Houde JV, Alcaide-Loridan C, Charron D, Al-Daccak R, Aoudjit F
Mol Cancer Res. 2008
PubMed ID: 18234961
Cloning and purification of functionally active Fas ligand interfering protein (FIP) expressed in Escherichia coli.
Wisniewski P, Master A, Kaminska B
Acta Biochim Pol. 2008
PubMed ID: 18204739
The lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation.
Haraldsson MK, Louis-Dit-Sully CA, Lawson BR, Sternik G, Santiago-Raber ML, Gascoigne NR, Theofilopoulos AN, Kono DH
Immunity. 2008
PubMed ID: 18199416
FAS -1377 G/A polymorphism and the risk of lymph node metastasis in cervical cancer.
Kang S, Dong SM, Seo SS, Kim JW, Park SY
Cancer Genet Cytogenet. 2008
PubMed ID: 18068525
Prognostic significance of the Fas-receptor/Fas-ligand system in cervical squamous cell carcinoma.
Lerma E, Romero M, Gallardo A, Pons C, Muñoz J, Fuentes J, Lloveras B, Catasus L, Prat J
Virchows Arch. 2008
PubMed ID: 18000680
Protection against lipopolysaccharide-induced myocardial dysfunction in mice by cardiac-specific expression of soluble Fas.
Niu J, Azfer A, Kolattukudy PE
J Mol Cell Cardiol. 2008
PubMed ID: 17996250
Fas Ag-FasL coupling leads to ERK1/2-mediated proliferation of gastric mucosal cells.
Li H, Cai X, Fan X, Moquin B, Stoicov C, Houghton J
Am J Physiol Gastrointest Liver Physiol. 2008
PubMed ID: 17991709
Fas 670 promoter polymorphism is associated to susceptibility, clinical presentation, and survival in adult T cell leukemia.
Farre L, Bittencourt AL, Silva-Santos G, Almeida A, Silva AC, Decanine D, Soares GM, Alcantara LC, Van Dooren S, Galvão-Castro B, Vandamme AM, Van Weyenbergh J
J Leukoc Biol. 2008
PubMed ID: 17962369
CD95 signaling deficient mice with a wild-type hematopoietic system are prone to hepatic neoplasia.
Park SM, Rajapaksha TW, Zhang M, Sattar HA, Fichera A, Ashton-Rickardt PG, Peter ME
Apoptosis. 2008
PubMed ID: 17955374
Umbilical cord blood stem cell mediated downregulation of fas improves functional recovery of rats after spinal cord injury.
Dasari VR, Spomar DG, Li L, Gujrati M, Rao JS, Dinh DH
Neurochem Res. 2008
PubMed ID: 17703359
Association between FAS polymorphism and prostate cancer development.
Lima L, Morais A, Lobo F, Calais-da-Silva FM, Calais-da-Silva FE, Medeiros R
Prostate Cancer Prostatic Dis. 2008
PubMed ID: 17667965
Evasion of myofibroblasts from immune surveillance: a mechanism for tissue fibrosis.
Wallach-Dayan SB, Golan-Gerstl R, Breuer R
Proc Natl Acad Sci U S A. 2007
PubMed ID: 18077384
A novel role of IL-2 in organ-specific autoimmune inflammation beyond regulatory T cell checkpoint: both IL-2 knockout and Fas mutation prolong lifespan of Scurfy mice but by different mechanisms.
Zheng L, Sharma R, Gaskin F, Fu SM, Ju ST
J Immunol. 2007
PubMed ID: 18056343
Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus of rat with global cerebral ischemia.
Wang YR, Liu RY, Wang LC, Mao HF, Chen JQ
Toxicon. 2007
PubMed ID: 17900647
Perforin-dependent apoptosis functionally compensates Fas deficiency in activation-induced cell death of human T lymphocytes.
Mateo V, Ménager M, de Saint-Basile G, Stolzenberg MC, Roquelaure B, André N, Florkin B, le Deist F, Picard C, Fischer A, Rieux-Laucat F
Blood. 2007
PubMed ID: 17724145
YAP1 increases organ size and expands undifferentiated progenitor cells.
Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR
Curr Biol. 2007
PubMed ID: 17980593
Expression of CD95 and CD95L on astrocytes in the CA1 area of the immature rat hippocampus after hypoxia-ischemia injury.
Kim MJ, Lim HS, Yoo YB, Lee YI, Hahm DH, Lee HJ, Jung KW, Kim JW, Yoe SM, Chung DC, Chang YP
Comp Med. 2007
PubMed ID: 18246871
Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients.
Koshkina NV, Kleinerman ES, Li G, Zhao CC, Wei Q, Sturgis EM
J Pediatr Hematol Oncol. 2007
PubMed ID: 18090928
[Effect of fas mRNA expression on cytochrome C-induced apoptosis of HL-60 cells in vitro]
Chen HQ, Chen MZ, Chen RL, Fang XM, Xu XH, Feng HJ
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007
PubMed ID: 18088463
Aqueous humor levels of soluble Fas and Fas-ligand in patients with primary open angle and pseudoexfoliation glaucoma.
Razeghinejad MR, Kamali-Sarvestani E
Iran J Immunol. 2007
PubMed ID: 18057579
Autoimmune Th2-mediated dacryoadenitis in MRL/MpJ mice becomes Th1-mediated in IL-4 deficient MRL/MpJ mice.
Jabs DA, Prendergast RA, Campbell AL, Lee B, Akpek EK, Gérard HC, Hudson AP, Whittum-Hudson JA
Invest Ophthalmol Vis Sci. 2007
PubMed ID: 18055812
Transgenic expression of Bcl-xL or Bcl-2 by murine B cells enhances the in vivo antipolysaccharide, but not antiprotein, response to intact Streptococcus pneumoniae.
Chattopadhyay G, Khan AQ, Sen G, Colino J, DuBois W, Rubtsov A, Torres RM, Potter M, Snapper CM
J Immunol. 2007
PubMed ID: 18025197
Interferon-gamma and tumor necrosis factor-alpha sensitize primarily resistant human endometrial stromal cells to Fas-mediated apoptosis.
Fluhr H, Krenzer S, Stein GM, Stork B, Deperschmidt M, Wallwiener D, Wesselborg S, Zygmunt M, Licht P
J Cell Sci. 2007
PubMed ID: 18003704
Genetic polymorphisms in the apoptosis-associated genes FAS and FASL and breast cancer risk.
Crew KD, Gammon MD, Terry MB, Zhang FF, Agrawal M, Eng SM, Sagiv SK, Teitelbaum SL, Neugut AI, Santella RM
Carcinogenesis. 2007
PubMed ID: 17962219
Lipopolysaccharide and interferon-gamma enhance Fas-mediated cell death in mouse vascular endothelial cells via augmentation of Fas expression.
Koide N, Morikawa A, Tumurkhuu G, Dagvadorj J, Hassan F, Islam S, Naiki Y, Mori I, Yoshida T, Yokochi T
Clin Exp Immunol. 2007
PubMed ID: 17900305
Protein kinase C-zeta (PKC-zeta) regulates Kupffer cell apoptosis during experimental sepsis.
Peng Y, Sigua CA, Karsonovich C, Murr MM
J Gastrointest Surg. 2007
PubMed ID: 17899301
Actin integrity is indispensable for CD95/Fas-induced apoptosis of HIV-specific CD8+ T cells.
Petrovas C, Mueller YM, Yang G, Altork SR, Jacobson JM, Pitsakis PG, Mounzer KC, Altman JD, Katsikis PD
Apoptosis. 2007
PubMed ID: 17891455
Increased apoptosis of circulating T cells in myelodysplastic syndromes.
Shioi Y, Tamura H, Yokose N, Satoh C, Dan K, Ogata K
Leuk Res. 2007
PubMed ID: 17485109
Reduced receptor editing in lupus-prone MRL/lpr mice.
Lamoureux JL, Watson LC, Cherrier M, Skog P, Nemazee D, Feeney AJ
J Exp Med. 2007
PubMed ID: 17967905
N-acetyl cysteine and caffeic acid phenethyl ester sensitize astrocytoma cells to Fas-mediated cell death in a redox-dependent manner.
Choi K, Han YH, Choi C
Cancer Lett. 2007
PubMed ID: 17692455
Resistance to Ara-C up-regulates the activation of NF-kappaB, telomerase activity and Fas expression in NALM-6 cells.
Kanno S, Hiura T, Shouji A, Osanai Y, Ujibe M, Ishikawa M
Biol Pharm Bull. 2007
PubMed ID: 17978477
Cutting edge: two distinct motifs within the Fas ligand tail regulate Fas ligand-mediated costimulation.
Sun M, Lee S, Karray S, Levi-Strauss M, Ames KT, Fink PJ
J Immunol. 2007
PubMed ID: 17947633
Apoptosis in the kidneys of patients with type II diabetic nephropathy.
Verzola D, Gandolfo MT, Ferrario F, Rastaldi MP, Villaggio B, Gianiorio F, Giannoni M, Rimoldi L, Lauria F, Miji M, Deferrari G, Garibotto G
Kidney Int. 2007
PubMed ID: 17851466
Promotion of Fas-mediated apoptosis in Type II cells by high doses of hepatocyte growth factor bypasses the mitochondrial requirement.
Zhao Y, Difrancesca D, Wang X, Zarnegar R, Michalopoulos GK, Yin XM
J Cell Physiol. 2007
PubMed ID: 17620325
Role of endogenous 4-1BB in the development of systemic lupus erythematosus.
Vinay DS, Choi JH, Kim JD, Choi BK, Kwon BS
Immunology. 2007
PubMed ID: 17608689
TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice.
Bermpohl D, You Z, Lo EH, Kim HH, Whalen MJ
J Cereb Blood Flow Metab. 2007
PubMed ID: 17406655
The apoptotic effects of oxidative stress and antiapoptotic effects of caspase inhibitors on rat notochordal cells.
Kim KW, Ha KY, Lee JS, Rhyu KW, An HS, Woo YK
Spine (Phila Pa 1976). 2007
PubMed ID: 18090083
Expression and distribution of S-100 protein, CD83 and apoptosis-related proteins (Fas, FasL and Bcl-2) in thyroid tissues of autoimmune thyroid diseases.
Xu WC, Chen SR, Huang JX, Zheng ZC, Chen LX, Lin JJ, Li YG
Eur J Histochem. 2007
PubMed ID: 18162459
Diminished myelin-specific T cell activation associated with increase in CTLA4 and Fas molecules in multiple sclerosis patients treated with IFN-beta.
Hallal-Longo DE, Mirandola SR, Oliveira EC, Farias AS, Pereira FG, Metze IL, Brandão CO, Ruocco HH, Damasceno BP, Santos LM
J Interferon Cytokine Res. 2007
PubMed ID: 17970696
Fas-negative osteosarcoma tumor cells are selected during metastasis to the lungs: the role of the Fas pathway in the metastatic process of osteosarcoma.
Koshkina NV, Khanna C, Mendoza A, Guan H, DeLauter L, Kleinerman ES
Mol Cancer Res. 2007
PubMed ID: 17951400
Alteration in kidney glucose and amino acids are implicated in renal pathology in MRL/lpr mice.
Alexander JJ, Zwingmann C, Jacob A, Quigg R
Biochim Biophys Acta. 2007
PubMed ID: 17942282
Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer.
Jain M, Kumar S, Upadhyay R, Lal P, Tiwari A, Ghoshal UC, Mittal B
Cancer Biol Ther. 2007
PubMed ID: 17912028
Crystallization and preliminary crystallographic analysis of the fourth FAS1 domain of human BigH3.
Yoo JH, Kim E, Kim J, Cho HS
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007
PubMed ID: 17909299
Absence of 4 1BB gene function exacerbates lacrimal gland inflammation in autoimmune-prone MRL-Faslpr mice.
Vinay DS, Kim JD, Asai T, Choi BK, Kwon BS
Invest Ophthalmol Vis Sci. 2007
PubMed ID: 17898284
Expression of Fas and Fas-ligand in donor hematopoietic stem and progenitor cells is dissociated from the sensitivity to apoptosis.
Pearl-Yafe M, Yolcu ES, Stein J, Kaplan O, Shirwan H, Yaniv I, Askenasy N
Exp Hematol. 2007
PubMed ID: 17889725
IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression.
Yang D, Thangaraju M, Browning DD, Dong Z, Korchin B, Lev DC, Ganapathy V, Liu K
J Immunol. 2007
PubMed ID: 17878376
Phosphatidylinositol 3-kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells.
Su CC, Lin YP, Cheng YJ, Huang JY, Chuang WJ, Shan YS, Yang BC
J Immunol. 2007
PubMed ID: 17878356
CD83 expression is a sensitive marker of activation required for B cell and CD4+ T cell longevity in vivo.
Prazma CM, Yazawa N, Fujimoto Y, Fujimoto M, Tedder TF
J Immunol. 2007
PubMed ID: 17878352
Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent.
Zhang B, Maris CH, Foell J, Whitmire J, Niu L, Song J, Kwon BS, Vella AT, Ahmed R, Jacob J, Mittler RS
J Clin Invest. 2007
PubMed ID: 17853940
Autosomal loci associated with a sex-related difference in the development of autoimmune phenotypes in a lupus model.
Misu N, Zhang M, Mori S, Miyazaki T, Furukawa H, Sasaki T, Nose M, Ono M
Eur J Immunol. 2007
PubMed ID: 17823981
Fas/FasL-mediated apoptosis in the arcuate nucleus and medial preoptic area of male ArKO mice is ameliorated by selective estrogen receptor alpha and estrogen receptor beta agonist treatment, respectively.
Hill RA, Chow J, Fritzemeier K, Simpson ER, Boon WC
Mol Cell Neurosci. 2007
PubMed ID: 17716913
Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages.
Takada Y, Sung B, Sethi G, Chaturvedi MM, Aggarwal BB
Biochem Pharmacol. 2007
PubMed ID: 17692826
Immature and neurally differentiated mouse embryonic stem cells do not express a functional Fas/Fas ligand system.
Brunlid G, Pruszak J, Holmes B, Isacson O, Sonntag KC
Stem Cells. 2007
PubMed ID: 17615270
Gamma c cytokines condition the progressive differentiation of CD4+ T cells.
Masse GX, Corcuff E, Strick-Marchand H, Guy-Grand D, Tafuri-Bladt A, Albert ML, Lantz O, Di Santo JP
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17855567
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts.
Nakamura T, Imai Y, Matsumoto T, Sato S, Takeuchi K, Igarashi K, Harada Y, Azuma Y, Krust A, Yamamoto Y, Nishina H, Takeda S, Takayanagi H, Metzger D, Kanno J, Takaoka K, Martin TJ, Chambon P, Kato S
Cell. 2007
PubMed ID: 17803905
Soluble Fas and soluble Fas ligand in the joints of patients with rheumatoid arthritis and osteoarthritis: a Tunisian case-control study.
Mrabet D, Hajri R, Hamzaoui K, Attia Romdhane N, Zakraoui L
Clin Exp Rheumatol. 2007
PubMed ID: 18078642
[Relationship between FAS/FASL gene polymorphisms and susceptibility of coal worker's pneumoconiosis]
Ni CH, Song ZF, Jia XM, Li AP, Li CP, Li SK, Li YM, Wang ZL, Zhou Y, Wang SY, Zhang ZD, Zhou JW
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007
PubMed ID: 17997887
Macrophages prevent the differentiation of autoreactive B cells by secreting CD40 ligand and interleukin-6.
Kilmon MA, Wagner NJ, Garland AL, Lin L, Aviszus K, Wysocki LJ, Vilen BJ
Blood. 2007
PubMed ID: 17712049
Lack of Fas antagonism by Met in human fatty liver disease.
Zou C, Ma J, Wang X, Guo L, Zhu Z, Stoops J, Eaker AE, Johnson CJ, Strom S, Michalopoulos GK, DeFrances MC, Zarnegar R
Nat Med. 2007
PubMed ID: 17704785
A biochemical mechanism for resistance of intervertebral discs to metastatic cancer: Fas ligand produced by disc cells induces apoptotic cell death of cancer cells.
Park JB, Lee JK, Cho ST, Park EY, Riew KD
Eur Spine J. 2007
PubMed ID: 17684774
Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Huerta S, Heinzerling JH, Anguiano-Hernandez YM, Huerta-Yepez S, Lin J, Chen D, Bonavida B, Livingston EH
J Surg Res. 2007
PubMed ID: 17603079
OBF-1 is essential for the generation of antibody-secreting cells and the development of autoimmunity in MRL-lpr mice.
Zuo J, Ge H, Zhu G, Matthias P, Sun J
J Autoimmun. 2007
PubMed ID: 17574818
Fas antigen and sporadic Alzheimer's disease in Southern Italy: evaluation of two polymorphisms in the TNFRSF6 gene.
Andreoli V, Nicoletti G, Romeo N, Condino F, La Russa A, Liguori M, Manna I, Spadafora P, Quattrone A, Cittadella R
Neurochem Res. 2007
PubMed ID: 17406980
MHC class II+ exosomes in plasma suppress inflammation in an antigen-specific and Fas ligand/Fas-dependent manner.
Kim SH, Bianco NR, Shufesky WJ, Morelli AE, Robbins PD
J Immunol. 2007
PubMed ID: 17675484
Analysis of apoptotic markers Fas/FasL (CD95/CD95L) expression on the lymphocytes in patients with acute coronary syndrome.
Bossowska A, Bossowski A, Galar B
Kardiol Pol. 2007
PubMed ID: 17853317
The Fas/Fas-ligand pathway does not mediate the apoptosis in elastase-induced emphysema in mice.
Sawada M, Ohno Y, La BL, Funaguchi N, Asai T, Yuhgetsu H, Takemura G, Minatoguchi S, Fujiwara H, Fujiwara T
Exp Lung Res. 2007
PubMed ID: 17694438
Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers.
Grossman I, Avidan N, Singer C, Goldstaub D, Hayardeny L, Eyal E, Ben-Asher E, Paperna T, Pe'er I, Lancet D, Beckmann JS, Miller A
Pharmacogenet Genomics. 2007
PubMed ID: 17622942
c-FLIP expression in colorectal carcinomas: association with Fas/FasL expression and prognostic implications.
Korkolopoulou P, Saetta AA, Levidou G, Gigelou F, Lazaris A, Thymara I, Scliri M, Bousboukea K, Michalopoulos NV, Apostolikas N, Konstantinidou A, Tzivras M, Patsouris E
Histopathology. 2007
PubMed ID: 17559541
CD44v7 ligation downregulates the inflammatory immune response in Crohn's disease patients by apoptosis induction in mononuclear cells from the lamina propria.
Hoffmann U, Heilmann K, Hayford C, Stallmach A, Wahnschaffe U, Zeitz M, Günthert U, Wittig BM
Cell Death Differ. 2007
PubMed ID: 17479111
Essential role of MMP-12 in Fas-induced lung fibrosis.
Matute-Bello G, Wurfel MM, Lee JS, Park DR, Frevert CW, Madtes DK, Shapiro SD, Martin TR
Am J Respir Cell Mol Biol. 2007
PubMed ID: 17446527
[Study on the effect of iodine excess on cell apoptosis in rat thyroid cells (FRTL)]
Xu J, Liu X, Yang X, Li L, et al
Wei Sheng Yan Jiu. 2007
PubMed ID: 17953211
Importance of FAS-1377, FAS-670, and FASL-844 polymorphisms in tumor onset, progression, and pigment phenotypes of Swedish patients with melanoma: a case-control analysis.
Zhang H, Sun XF, Synnerstad I, Rosdahl I
Cancer J. 2007
PubMed ID: 17762757
Fas-1377 A/G polymorphism in lung cancer.
Gormus U, Ergen A, Yaylim-Eraltan I, Yilmaz H, Turna A, Bozkurt N, Isbir T
In Vivo. 2007
PubMed ID: 17708363
U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Corsini L, Bonnal S, Bonna S, Basquin J, Hothorn M, Scheffzek K, Valcárcel J, Sattler M
Nat Struct Mol Biol. 2007
PubMed ID: 17589525
Increased Fas and Bcl-2 expression on peripheral mononuclear cells from patients with active juvenile-onset systemic lupus erythematosus.
Liphaus BL, Kiss MH, Carrasco S, Goldenstein-Schainberg C
J Rheumatol. 2007
PubMed ID: 17516614
Up-regulation of c-FLIPS+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL.
Troeger A, Schmitz I, Siepermann M, Glouchkova L, Gerdemann U, Janka-Schaub GE, Schulze-Osthoff K, Dilloo D
Blood. 2007
PubMed ID: 17376892
Crosstalk between RANKL and Fas signaling in dendritic cells controls immune tolerance.
Izawa T, Ishimaru N, Moriyama K, Kohashi M, Arakaki R, Hayashi Y
Blood. 2007
PubMed ID: 17371940
Characterization of reciprocal Lmb1-4 interval MRL-Faslpr and C57BL/6-Faslpr congenic mice reveals significant effects from Lmb3.
Santiago-Raber ML, Haraldsson MK, Theofilopoulos AN, Kono DH
J Immunol. 2007
PubMed ID: 17548658
Serum levels of sFas and sFasL during chemotherapy of lung cancer.
Naumnik W, Izycki T, Ossolinska M, Chyczewska E
Exp Oncol. 2007
PubMed ID: 17704746
A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas.
Villa-Morales M, Santos J, Pérez-Gómez E, Quintanilla M, Fernández-Piqueras J
Cancer Res. 2007
PubMed ID: 17545588
Absence of functional alternative complement pathway alleviates lupus cerebritis.
Alexander JJ, Jacob A, Vezina P, Sekine H, Gilkeson GS, Quigg RJ
Eur J Immunol. 2007
PubMed ID: 17523212
Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice.
Jiang C, Foley J, Clayton N, Kissling G, Jokinen M, Herbert R, Diaz M
J Immunol. 2007
PubMed ID: 17513793
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.
Le AV, Cho JY, Miller M, McElwain S, Golgotiu K, Broide DH
J Immunol. 2007
PubMed ID: 17513781
A polymorphism in FAS gene promoter correlated with circulating soluble FAS levels.
Mahfoudh W, Bel Hadj Jrad B, Romdhane A, Chouchane L
Int J Immunogenet. 2007
PubMed ID: 17504511
Fas ligand enhances hematopoietic cell engraftment through abrogation of alloimmune responses and nonimmunogenic interactions.
Pearl-Yafe M, Yolcu ES, Stein J, Kaplan O, Yaniv I, Shirwan H, Askenasy N
Stem Cells. 2007
PubMed ID: 17363551
Fas/Fas ligand gene polymorphism in patients with papillary thyroid cancer in the Turkish population.
Erdogan M, Karadeniz M, Berdeli A, Tamsel S, Ertan Y, Uluer H, Yilmaz C, Tuzun M, Kabalak T, Ozgen AG
J Endocrinol Invest. 2007
PubMed ID: 17598974
FasL, Fas, and death-inducing signaling complex (DISC) proteins are recruited to membrane rafts after spinal cord injury.
Davis AR, Lotocki G, Marcillo AE, Dietrich WD, Keane RW
J Neurotrauma. 2007
PubMed ID: 17518537
Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.
Stranges PB, Watson J, Cooper CJ, Choisy-Rossi CM, Stonebraker AC, Beighton RA, Hartig H, Sundberg JP, Servick S, Kaufmann G, Fink PJ, Chervonsky AV
Immunity. 2007
PubMed ID: 17509906
Mutations within the 5' region of FAS/CD95 gene in nodal diffuse large B-cell lymphoma.
Scholl V, Stefanoff CG, Hassan R, Spector N, Renault IZ
Leuk Lymphoma. 2007
PubMed ID: 17487740
Met signals hepatocyte survival by preventing Fas-triggered FLIP degradation in a PI3k-Akt-dependent manner.
Moumen A, Ieraci A, Patané S, Solé C, Comella JX, Dono R, Maina F
Hepatology. 2007
PubMed ID: 17464994
Defective DNA methylation and CD70 overexpression in CD4+ T cells in MRL/lpr lupus-prone mice.
Sawalha AH, Jeffries M
Eur J Immunol. 2007
PubMed ID: 17429846
Alleviation of ischemia-reperfusion injury in rat liver transplantation by induction of small interference RNA targeting Fas.
Li X, Zhang JF, Lu MQ, Yang Y, Xu C, Li H, Wang GS, Cai CJ, Chen GH
Langenbecks Arch Surg. 2007
PubMed ID: 17235585
Lymphocyte expression of CD95 at rest and in response to acute exercise in healthy children and adolescents.
Timmons BW, Bar-Or O
Brain Behav Immun. 2007
PubMed ID: 17194564
Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer.
Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, Shi Y, Tan W, Zhou Y, Zhao D, Zhang X, Guo Y, Lin D
Carcinogenesis. 2007
PubMed ID: 17183065
Role for Msh5 in the regulation of Ig class switch recombination.
Sekine H, Ferreira RC, Pan-Hammarström Q, Graham RR, Ziemba B, de Vries SS, Liu J, Hippen K, Koeuth T, Ortmann W, Iwahori A, Elliott MK, Offer S, Skon C, Du L, Novitzke J, Lee AT, Zhao N, Tompkins JD, Altshuler D, Gregersen PK, Cunningham-Rundles C, Harris RS, Her C, Nelson DL, Hammarström L, Gilkeson GS, Behrens TW
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17409188
PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr.
Xie C, Patel R, Wu T, Zhu J, Henry T, Bhaskarabhatla M, Samudrala R, Tus K, Gong Y, Zhou H, Wakeland EK, Zhou XJ, Mohan C
Int Immunol. 2007
PubMed ID: 17369192
BAFF and LPS cooperate to induce B cells to become susceptible to CD95/Fas-mediated cell death.
Acosta-Rodríguez EV, Craxton A, Hendricks DW, Merino MC, Montes CL, Clark EA, Gruppi A
Eur J Immunol. 2007
PubMed ID: 17357108
FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis.
Xiang Z, Cutler AJ, Brownlie RJ, Fairfax K, Lawlor KE, Severinson E, Walker EU, Manz RA, Tarlinton DM, Smith KG
Nat Immunol. 2007
PubMed ID: 17322888
The Fas death pathway controls coordinated expansions of type 1 CD8 and type 2 CD4 T cells in Trypanosoma cruzi infection.
Guillermo LV, Silva EM, Ribeiro-Gomes FL, De Meis J, Pereira WF, Yagita H, DosReis GA, Lopes MF
J Leukoc Biol. 2007
PubMed ID: 17261545
ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.
Feng X, Li H, Rumbin AA, Wang X, La Cava A, Brechtelsbauer K, Castellani LW, Witztum JL, Lusis AJ, Tsao BP
J Lipid Res. 2007
PubMed ID: 17259598
Enhanced CD95-mediated apoptosis contributes to radiation hypersensitivity of NBS lymphoblasts.
Sagan D, Mörtl S, Müller I, Eckardt-Schupp F, Eichholtz-Wirth H
Apoptosis. 2007
PubMed ID: 17219051
CD95 tyrosine phosphorylation is required for CD95 oligomerization.
Eberle A, Reinehr R, Becker S, Keitel V, Häussinger D
Apoptosis. 2007
PubMed ID: 17195092
Glucocorticoid impact on cochlear function and systemic side effects in autoimmune C3.MRL-Faslpr and normal C3H/HeJ mice.
Trune DR, Kempton JB, Harrison AR, Wobig JL
Hear Res. 2007
PubMed ID: 17098384
[Study of apoptosis and Fas expression of peritoneal fluid and peripheral blood T lymphocytes in patients with epithelial ovarian cancer and their relationship with CA125].
Ma YX, Ye F, Chen HZ, Lü WG, Xie X
Zhonghua Yi Xue Za Zhi. 2007
PubMed ID: 17565840
The Fas/Fas ligand system inhibits differentiation of murine osteoblasts but has a limited role in osteoblast and osteoclast apoptosis.
Kovacić N, Lukić IK, Grcević D, Katavić V, Croucher P, Marusić A
J Immunol. 2007
PubMed ID: 17339432
A functional Fas promoter polymorphism is associated with a severe phenotype in type 1 autoimmune hepatitis characterized by early development of cirrhosis.
Agarwal K, Czaja AJ, Donaldson PT
Tissue Antigens. 2007
PubMed ID: 17493146
Fas-1377A/G and FasL-844 T/C gene polymorphisms and epithelial ovarian cancer.
Gormus U, Ergen A, Yilmaz H, Dalan B, Berkman S, Isbir T
Anticancer Res. 2007
PubMed ID: 17465232
Lymphocytic infiltration and goblet cell marker alteration in the conjunctiva of the MRL/MpJ-Fas(lpr) mouse model of Sjögren's syndrome.
Diebold Y, Chen LL, Tepavcevic V, Ferdman D, Hodges RR, Dartt DA
Exp Eye Res. 2007
PubMed ID: 17208228
Up-regulation of CD95 (Apo-1/Fas) is associated with spermatocyte apoptosis during the first round of spermatogenesis in the rat.
Lizama C, Alfaro I, Reyes JG, Moreno RD
Apoptosis. 2007
PubMed ID: 17195944
K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis.
Wang S, Wang S, Maeng H, Young DP, Prakash O, Fayad LE, Younes A, Samaniego F
Blood. 2007
PubMed ID: 17090655
Elevated levels of soluble Fas (APO-1, CD95), soluble Fas ligand, and matrix metalloproteinase-3 in sera from patients with active untreated adult onset Still's disease.
Chen DY, Lan JL, Lin FJ, Hsieh TY
Clin Rheumatol. 2007
PubMed ID: 16972019
Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis.
Liu T, Laurell C, Selivanova G, Lundeberg J, Nilsson P, Wiman KG
Cell Death Differ. 2007
PubMed ID: 16917513
The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling.
Bosque A, Aguiló JI, Alava MA, Paz-Artal E, Naval J, Allende LM, Anel A
Blood. 2007
PubMed ID: 17062728
The variation in Fas localization and the changes in Fas expression level upon stimulation with growth factors.
Omoteyama K, Inoue S
Biochem Biophys Res Commun. 2007
PubMed ID: 17174268
Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies.
Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kirber MT, Summer RS, Kihara S, Walsh K
J Clin Invest. 2007
PubMed ID: 17256056
Fas- and FasL-deficient mice are resistant to the induction of bleomycin-induced scleroderma.
Yamamoto T, Yokozeki H, Nishioka K
Arch Dermatol Res. 2007
PubMed ID: 17102953
Unexpected development of autoimmunity in BAFF-R-mutant MRL-lpr mice.
Ju ZL, Shi GY, Zuo JX, Zhang JW, Jian Sun
Immunology. 2007
PubMed ID: 17073941
Sex-specific effect of the Val1483Ile polymorphism in the fatty acid synthase gene (FAS) on body mass index and lipid profile in Caucasian children.
Körner A, Ma L, Franks PW, Kiess W, Baier LJ, Stumvoll M, Kovacs P
Int J Obes (Lond). 2007
PubMed ID: 16788566
Large-scale phosphorylation analysis of mouse liver.
Villén J, Beausoleil SA, Gerber SA, Gygi SP
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17242355
Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing.
Izquierdo JM, Valcárcel J
J Biol Chem. 2007
PubMed ID: 17135269
Chemokines CCL19 and CCL21 promote activation-induced cell death of antigen-responding T cells.
Yasuda T, Kuwabara T, Nakano H, Aritomi K, Onodera T, Lipp M, Takahama Y, Kakiuchi T
Blood. 2007
PubMed ID: 16973962
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.
Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, Chien KR, Riley PR
Nature. 2007
PubMed ID: 17108969
Palmitoylation is required for efficient Fas cell death signaling.
Chakrabandhu K, Hérincs Z, Huault S, Dost B, Peng L, Conchonaud F, Marguet D, He HT, Hueber AO
EMBO J. 2007
PubMed ID: 17159908
Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling.
Feig C, Tchikov V, Schütze S, Peter ME
EMBO J. 2007
PubMed ID: 17159907
[Assessment of sFas concentration in serum of uveitis patients]
Mrugacz M, Bakunowicz-Lazarczyk A, Sredzińska-Kita D, Zelazowska-Rutkowska B, Wysocka J
Klin Oczna. 2007
PubMed ID: 18488389
Concentrations of ssDNA in liver tissue and its correlation with sFas and sFasL in serum of patients infected with HBV, HCV, HCV and HIV.
Łapinski TW, Wiercińska-Drapało A, Panasiuk A, Kovalchuk O
Adv Med Sci. 2007
PubMed ID: 18217400
Putative association of Fas and FasL gene polymorphisms with clinical outcomes of hepatitis B virus infection.
Jung YJ, Kim YJ, Kim LH, Lee SO, Park BL, Shin HD, Lee HS
Intervirology. 2007
PubMed ID: 17938571
Inhibition of apoptosis by expression of antiapoptotic proteins in recombinant human keratinocytes.
Choi CY, Reimers K, Allmeling C, Kall S, Choi YH, Vogt PM
Cell Transplant. 2007
PubMed ID: 17912957
Resistance to fas-induced apoptosis in cells from human atherosclerotic lesions: elevated Bcl-XL inhibits apoptosis and caspase activation.
Yang Z, Gagarin D, Ramezani A, Hawley RG, McCaffrey TA
J Vasc Res. 2007
PubMed ID: 17657164
Expression of FAS/APO 1/CD 95 in thyroid tumors.
Rzeszutko M, Rzeszutko W, Dziegiel P, Balcerzak W, Kaliszewski K, Bolanowski M
Folia Histochem Cytobiol. 2007
PubMed ID: 17597021
Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.
Jain M, Kumar S, Lal P, Tiwari A, Ghoshal UC, Mittal B
Cancer Detect Prev. 2007
PubMed ID: 17561354
Requirement of N-glycosylation for the secretion of recombinant extracellular domain of human Fas in HeLa cells.
Li Y, Yang X, Nguyen AH, Brockhausen I
Int J Biochem Cell Biol. 2007
PubMed ID: 17544837
Hsp70 may protect cardiomyocytes from stress-induced injury by inhibiting Fas-mediated apoptosis.
Zhao Y, Wang W, Qian L
Cell Stress Chaperones. 2007
PubMed ID: 17441510
Fas/Fas-ligand expressions in primary breast cancer are significant predictors of its skeletal spread.
Bebenek M, Duś D, Koźlak J
Anticancer Res. 2007
PubMed ID: 17352235
Autoimmune lymphoproliferative syndrome (ALPS) in a patient with a new germline Fas gene mutation.
Del-Rey MJ, Manzanares J, Bosque A, Aguiló JI, Gómez-Rial J, Roldan E, Serrano A, Anel A, Paz-Artal E, Allende LM
Immunobiology. 2007
PubMed ID: 17336828
Oocyte growth and follicular development in KIT-deficient Fas-knockout mice.
Moniruzzaman M, Sakamaki K, Akazawa Y, Miyano T
Reproduction. 2007
PubMed ID: 17244738
Fas (CD95) alters neuronal nitric oxide synthase expression to contribute in diabetic gastroparesis.
Surendran S
Med Hypotheses. 2007
PubMed ID: 17161551
Serum soluble Fas levels in patients with autoimmune rheumatic diseases.
Sahin M, Aydintug O, Tunc SE, Tutkak H, Naziroğlu M
Clin Biochem. 2007
PubMed ID: 17056024
Increased soluble Fas plasma levels in subjects at high cardiovascular risk: Atorvastatin on Inflammatory Markers (AIM) study, a substudy of ACTFAST.
Blanco-Colio LM, Martín-Ventura JL, de Teresa E, Farsang C, Gaw A, Gensini G, Leiter LA, Langer A, Martineau P, Hérnandez G, Egido J, ACTFAST investigators
Arterioscler Thromb Vasc Biol. 2007
PubMed ID: 17053166
Role of dioxin response element and nuclear factor-kappaB motifs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated regulation of Fas and Fas ligand expression.
Singh NP, Nagarkatti M, Nagarkatti PS
Mol Pharmacol. 2007
PubMed ID: 16940415
Disparate distribution of 16 candidate single nucleotide polymorphisms among racial and ethnic groups of pediatric heart transplant patients.
Girnita DM, Webber SA, Ferrell R, Burckart GJ, Brooks MM, McDade KK, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Girnita AL, Zeevi A
Transplantation. 2006
PubMed ID: 17198275
Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice.
He X, Schoeb TR, Panoskaltsis-Mortari A, Zinn KR, Kesterson RA, Zhang J, Samuel S, Hicks MJ, Hickey MJ, Bullard DC
J Immunol. 2006
PubMed ID: 17142777
Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis.
Wozniak AL, Wang X, Stieren ES, Scarbrough SG, Elferink CJ, Boehning D
J Cell Biol. 2006
PubMed ID: 17130290
Polymorphisms in the FAS and FASL genes and risk of lung cancer in a Korean population.
Park SH, Choi JE, Kim EJ, Jang JS, Lee WK, Cha SI, Kim CH, Kam S, Kim DS, Park RW, Kim YC, Han SB, Jung TH, Park JY
Lung Cancer. 2006
PubMed ID: 17014925
Retinal glial cell responses and Fas/FasL activation in rats with chronic ocular hypertension.
Ju KR, Kim HS, Kim JH, Lee NY, Park CK
Brain Res. 2006
PubMed ID: 17045251
Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus.
Sekine H, Graham KL, Zhao S, Elliott MK, Ruiz P, Utz PJ, Gilkeson GS
J Immunol. 2006
PubMed ID: 17082662
Severe focal sialadenitis and dacryoadenitis in NZM2328 mice induced by MCMV: a novel model for human Sjögren's syndrome.
Ohyama Y, Carroll VA, Deshmukh U, Gaskin F, Brown MG, Fu SM
J Immunol. 2006
PubMed ID: 17082658
Absence of Bcl-2 and Fas/CD95/APO-1 predicts the response to immunotherapy in metastatic renal cell carcinoma.
Maruyama R, Yamana K, Itoi T, Hara N, Bilim V, Nishiyama T, Takahashi K, Tomita Y
Br J Cancer. 2006
PubMed ID: 17031406
Tissue polypeptide specific antigen and soluble Fas during normal pregnancy and early life.
Protonotariou E, Rizos D, Malamitsi-Puchner A, Sarandakou A, Botsis D
In Vivo. 2006
PubMed ID: 17203787
The effects of interleukin-10 on the expression of Fas and FasL in rat hepatic stellate cells.
Zhang L, Wang X, Zheng W, Shi M
Med Chem. 2006
PubMed ID: 17105443
Deficient Fas expression by CD4+ CCR5+ T cells in multiple sclerosis.
Julià E, Montalban X, Al-Zayat H, Issazadeh-Navikas S, Goertsches R, Martin R, Comabella M
J Neuroimmunol. 2006
PubMed ID: 16899302
Macrophage migration inhibitory factor deficiency attenuates macrophage recruitment, glomerulonephritis, and lethality in MRL/lpr mice.
Hoi AY, Hickey MJ, Hall P, Yamana J, O'Sullivan KM, Santos LL, James WG, Kitching AR, Morand EF
J Immunol. 2006
PubMed ID: 17015758
Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal.
Li J, Sharma R, Patrick B, Sharma A, Jeyabal PV, Reddy PM, Saini MK, Dwivedi S, Dhanani S, Ansari NH, Zimniak P, Awasthi S, Awasthi YC
Biochemistry. 2006
PubMed ID: 17014078
Induction of apoptosis on human hepatocarcinoma cell lines by an alkyl resorcinol isolated from Lithraea molleoides.
Barbini L, Lopez P, Ruffa J, Martino V, Ferraro G, Campos R, Cavallaro L
World J Gastroenterol. 2006
PubMed ID: 17009393
Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis.
Samraj AK, Keil E, Ueffing N, Schulze-Osthoff K, Schmitz I
J Biol Chem. 2006
PubMed ID: 16895904
Blood-soluble Fas levels are increased in type 2 diabetic patients with peripheral vascular disease.
García-Unzueta MT, Pesquera C, Calzada E, De la Mora A, Muñoz P, Llorca J, Morchón N, Fernández-González MD, Amado JA
Horm Metab Res. 2006
PubMed ID: 17075777
Intracellular protein modification associated with altered T cell functions in autoimmunity.
Yang ML, Doyle HA, Gee RJ, Lowenson JD, Clarke S, Lawson BR, Aswad DW, Mamula MJ
J Immunol. 2006
PubMed ID: 16982891
B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation.
Yan J, Harvey BP, Gee RJ, Shlomchik MJ, Mamula MJ
J Immunol. 2006
PubMed ID: 16982884
Fas (CD95) ligation inhibits activation of NF-kappa B by targeting p65-Rel A in a caspase-dependent manner.
Wong HK, Tsokos GC
Clin Immunol. 2006
PubMed ID: 16765090
Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck.
Zhang Z, Wang LE, Sturgis EM, El-Naggar AK, Hong WK, Amos CI, Spitz MR, Wei Q
Clin Cancer Res. 2006
PubMed ID: 17000697
IL-6 protects enterocytes from hypoxia-induced apoptosis by induction of bcl-2 mRNA and reduction of fas mRNA.
Rollwagen FM, Madhavan S, Singh A, Li YY, Wolcott K, Maheshwari R
Biochem Biophys Res Commun. 2006
PubMed ID: 16870148
Irradiation-induced pneumonitis mediated by the CD95/CD95-ligand system.
Heinzelmann F, Jendrossek V, Lauber K, Nowak K, Eldh T, Boras R, Handrick R, Henkel M, Martin C, Uhlig S, Köhler D, Eltzschig HK, Wehrmann M, Budach W, Belka C
J Natl Cancer Inst. 2006
PubMed ID: 16954477
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.
Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ
Immunity. 2006
PubMed ID: 16973389
[Role of Fas-FasL and caspase-3 signal transduction pathway in promoting apoptosis of T lymphocyte subset in SLE patients]
Chen X, Wang LL, Cai B, Chen J, Feng WH
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2006
PubMed ID: 16948902
CD4 T cell-dependent autoimmunity against a melanocyte neoantigen induces spontaneous vitiligo and depends upon Fas-Fas ligand interactions.
Lambe T, Leung JC, Bouriez-Jones T, Silver K, Makinen K, Crockford TL, Ferry H, Forrester JV, Cornall RJ
J Immunol. 2006
PubMed ID: 16920942
Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation.
Tafani M, Karpinich NO, Serroni A, Russo MA, Farber JL
J Cell Physiol. 2006
PubMed ID: 16741989
Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway.
Kim DJ, Chung JH, Ryu EK, Rhim JH, Ryu YS, Park SH, Kim KT, Kang HS, Chung HK, Park SC
Exp Mol Med. 2006
PubMed ID: 16953119
H pylori receptor MHC class II contributes to the dynamic gastric epithelial apoptotic response.
Bland DA, Suarez G, Beswick EJ, Sierra JC, Reyes VE
World J Gastroenterol. 2006
PubMed ID: 16937440
Macrophages inhibit neovascularization in a murine model of age-related macular degeneration.
Apte RS, Richter J, Herndon J, Ferguson TA
PLoS Med. 2006
PubMed ID: 16903779
Autoreactive MZ and B-1 B-cell activation by Faslpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance.
Qian Y, Conway KL, Lu X, Seitz HM, Matsushima GK, Clarke SH
Blood. 2006
PubMed ID: 16861350
The cytoplasmic domain of Fas ligand costimulates TCR signals.
Sun M, Ames KT, Suzuki I, Fink PJ
J Immunol. 2006
PubMed ID: 16849454
Up-regulation of Fas expression by Pseudomonas aeruginosa-infected endothelial cells depends on modulation of iNOS and enhanced production of NO induced by bacterial type III secreted proteins.
Assis MC, Freitas C, Saliba AM, D'A Carvalho AP, Simao TA, Albano RM, Plotkowski MC
Int J Mol Med. 2006
PubMed ID: 16820946
Frequency and resistance of CD95 (Fas/Apo-1) gene-transfected tumor cells to CD95-mediated apoptosis by the elimination and methylation of integrated DNA.
Shimizu M, Yoshimoto T, Sato M, Matsuzawa A, Takeda Y
Int J Cancer. 2006
PubMed ID: 16506211
Caspase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis.
Lavrik IN, Golks A, Baumann S, Krammer PH
Blood. 2006
PubMed ID: 16822901
Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus.
Lartigue A, Courville P, Auquit I, François A, Arnoult C, Tron F, Gilbert D, Musette P
J Immunol. 2006
PubMed ID: 16818796
Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice.
Watson LC, Moffatt-Blue CS, McDonald RZ, Kompfner E, Ait-Azzouzene D, Nemazee D, Theofilopoulos AN, Kono DH, Feeney AJ
J Immunol. 2006
PubMed ID: 16818769
[Expression of Fas antigen and Fas ligand in acute liver injury induced by carbon tetrachloride in rat].
Wen T, Ren F, Liu Y, Wu ZM, Zhao JY
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2006
PubMed ID: 16831245
Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice.
Brummel R, Roberts TL, Stacey KJ, Lenert P
Eur J Immunol. 2006
PubMed ID: 16791898
Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development.
Zhang X, Cowan CM, Jiang X, Soo C, Miao S, Carpenter D, Wu B, Kuroda S, Ting K
Lab Invest. 2006
PubMed ID: 16652108
A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation.
Rubiolo C, Piazzolla D, Meissl K, Beug H, Huber JC, Kolbus A, Baccarini M
Blood. 2006
PubMed ID: 16527894
Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo.
Liu Y, Pop R, Sadegh C, Brugnara C, Haase VH, Socolovsky M
Blood. 2006
PubMed ID: 16527892
Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.
Zhao Z, Deocharan B, Scherer PE, Ozelius LJ, Putterman C
J Immunol. 2006
PubMed ID: 16751418
M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice.
Schenten D, Egert A, Pasparakis M, Rajewsky K
Blood. 2006
PubMed ID: 16493007
Somatic hypermutation of Ig genes is affected differently by failures in apoptosis caused by disruption of Fas (lpr mutation) or by overexpression of Bcl-2.
Mastache EF, Lindroth K, Fernández C, González-Fernández A
Scand J Immunol. 2006
PubMed ID: 16764695
Interferon-gamma induces Fas trafficking and sensitization to apoptosis in vascular smooth muscle cells via a PI3K- and Akt-dependent mechanism.
Rosner D, Stoneman V, Littlewood T, McCarthy N, Figg N, Wang Y, Tellides G, Bennett M
Am J Pathol. 2006
PubMed ID: 16723718
The role of noradrenergic nerves in the development of the lymphoproliferative disease in Fas-deficient, lpr/lpr mice.
del Rey A, Roggero E, Kabiersch A, Schäfer M, Besedovsky HO
J Immunol. 2006
PubMed ID: 16709870
Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells.
Chua CC, Liu X, Gao J, Hamdy RC, Chua BH
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16687611
Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma.
Tong J, Bandulwala HS, Clay BS, Anders RA, Shilling RA, Balachandran DD, Chen B, Weinstock JV, Solway J, Hamann KJ, Sperling AI
J Exp Med. 2006
PubMed ID: 16618792
HTLV-1 Tax protects against CD95-mediated apoptosis by induction of the cellular FLICE-inhibitory protein (c-FLIP).
Krueger A, Fas SC, Giaisi M, Bleumink M, Merling A, Stumpf C, Baumann S, Holtkotte D, Bosch V, Krammer PH, Li-Weber M
Blood. 2006
PubMed ID: 16403915
Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting.
Casola S, Cattoretti G, Uyttersprot N, Koralov SB, Seagal J, Segal J, Hao Z, Waisman A, Egert A, Ghitza D, Rajewsky K
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16651521
HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.
Anand AR, Ganju RK
J Biol Chem. 2006
PubMed ID: 16524887
Cerebral leucocyte infiltration in lupus-prone MRL/MpJ-fas lpr mice--roles of intercellular adhesion molecule-1 and P-selectin.
James WG, Hutchinson P, Bullard DC, Hickey MJ
Clin Exp Immunol. 2006
PubMed ID: 16634804
Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mice.
Chen C, Li H, Tian Q, Beardall M, Xu Y, Casanova N, Weigert M
J Immunol. 2006
PubMed ID: 16621982
Interferon regulatory factor-1 gene deletion decreases glomerulonephritis in MRL/lpr mice.
Reilly CM, Olgun S, Goodwin D, Gogal RM, Santo A, Romesburg JW, Ahmed SA, Gilkeson GS
Eur J Immunol. 2006
PubMed ID: 16541466
Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma.
Wang WS, Chen PM, Wang HS, Liang WY, Su Y
Carcinogenesis. 2006
PubMed ID: 16474169
Lipid rafts mediate ultraviolet light-induced Fas aggregation in M624 melanoma cells.
Elyassaki W, Wu S
Photochem Photobiol. 2006
PubMed ID: 16438619
Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively.
Hsiao HL, Wang WS, Chen PM, Su Y
Carcinogenesis. 2006
PubMed ID: 16364925
Antagonistic effects of nobiletin, a polymethoxyflavonoid, on eosinophilic airway inflammation of asthmatic rats and relevant mechanisms.
Wu YQ, Zhou CH, Tao J, Li SN
Life Sci. 2006
PubMed ID: 16337971
Oral nickel tolerance: Fas ligand-expressing invariant NK T cells promote tolerance induction by eliciting apoptotic death of antigen-carrying, effete B cells.
Nowak M, Kopp F, Roelofs-Haarhuis K, Wu X, Gleichmann E
J Immunol. 2006
PubMed ID: 16585548
Soluble Fas--a promising novel urinary marker for the detection of recurrent superficial bladder cancer.
Svatek RS, Herman MP, Lotan Y, Casella R, Hsieh JT, Sagalowsky AI, Shariat SF
Cancer. 2006
PubMed ID: 16541433
Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL.
Raoul C, Buhler E, Sadeghi C, Jacquier A, Aebischer P, Pettmann B, Henderson CE, Haase G
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16581901
[Effect of atorvastatin on Fas (CD95/Apo-1) expression in normal or ischemic brain].
Oria de Suárez C, Suárez Rodríguez S, Ponce Hernández L, Corado Ramírez J, Tovar Mendoza R, Eblen-Zajjurz A
An Med Interna. 2006
PubMed ID: 16796407
Granulocyte colony-stimulating factor reduces cardiomyocyte apoptosis and improves cardiac function in adriamycin-induced cardiomyopathy in rats.
Hou XW, Son J, Wang Y, Ru YX, Lian Q, Majiti W, Amazouzi A, Zhou YL, Wang PX, Han ZC
Cardiovasc Drugs Ther. 2006
PubMed ID: 16761189
[The level of Bcl-2 and Fas expression in thymoma tissue from patients with myasthenia gravis].
Shen G, Chai Y, Yue L, Wei HQ, Lin M
Zhonghua Jie He He Hu Xi Za Zhi. 2006
PubMed ID: 16750039
The Fas system may have a role in male reproduction.
Celik-Ozenci C, Sahin Z, Ustunel I, Akkoyunlu G, Erdogru T, Korgun ET, Baykara M, Demir R
Fertil Steril. 2006
PubMed ID: 16616089
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
NK cell-mediated immunopathology during an acute viral infection of the CNS.
Alsharifi M, Lobigs M, Simon MM, Kersten A, Müller K, Koskinen A, Lee E, Müllbacher A
Eur J Immunol. 2006
PubMed ID: 16541469
Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma.
Li C, Larson D, Zhang Z, Liu Z, Strom SS, Gershenwald JE, Prieto VG, Lee JE, Ross MI, Mansfield PF, Cormier JN, Duvic M, Grimm EA, Wei Q
Pharmacogenet Genomics. 2006
PubMed ID: 16538172
Functional polymorphisms in the promoter regions of the FAS and FAS ligand genes and risk of bladder cancer in south China: a case-control analysis.
Li C, Wu W, Liu J, Qian L, Li A, Yang K, Wei Q, Zhou J, Zhang Z
Pharmacogenet Genomics. 2006
PubMed ID: 16538171
Functional Fas (Cd95/Apo-1) promoter polymorphisms in inbred mouse strains exhibiting different susceptibility to gamma-radiation-induced thymic lymphoma.
Villa-Morales M, Santos J, Fernández-Piqueras J
Oncogene. 2006
PubMed ID: 16301997
Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway.
Schillaci R, Salatino M, Cassataro J, Proietti CJ, Giambartolomei GH, Rivas MA, Carnevale RP, Charreau EH, Elizalde PV
J Immunol. 2006
PubMed ID: 16517711
c-FLIP confers resistance to FAS-mediated apoptosis in anaplastic large-cell lymphoma.
Oyarzo MP, Medeiros LJ, Atwell C, Feretzaki M, Leventaki V, Drakos E, Amin HM, Rassidakis GZ
Blood. 2006
PubMed ID: 16304056
[The expression and role of Fas/FasL in infantile hemangioma]
Xing X, Ouyang TX, Yuan SM, Lu B, Ni CR, Yang ZY
Zhonghua Zheng Xing Wai Ke Za Zhi. 2006
PubMed ID: 16736614
Significance of Fas expression alteration during tumor progression of renal cell carcinoma.
Sejima T, Miyagawa I
Int J Urol. 2006
PubMed ID: 16643620
Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.
Temkin V, Huang Q, Liu H, Osada H, Pope RM
Mol Cell Biol. 2006
PubMed ID: 16507998
p38 mitogen-activated protein kinase mediates the Fas-induced mitochondrial death pathway in CD8+ T cells.
Farley N, Pedraza-Alva G, Serrano-Gomez D, Nagaleekar V, Aronshtam A, Krahl T, Thornton T, Rincón M
Mol Cell Biol. 2006
PubMed ID: 16507991
Fas (TNFRSF6) gene polymorphism in pregnant women with hemolysis, elevated liver enzymes, and low platelets and in their neonates.
Sziller I, Hupuczi P, Normand N, Halmos A, Papp Z, Witkin SS
Obstet Gynecol. 2006
PubMed ID: 16507928
C5b-9 terminal complex protects oligodendrocytes from apoptotic cell death by inhibiting caspase-8 processing and up-regulating FLIP.
Cudrici C, Niculescu F, Jensen T, Zafranskaia E, Fosbrink M, Rus V, Shin ML, Rus H
J Immunol. 2006
PubMed ID: 16493077
Role of CD95-mediated adipocyte loss in autoimmune lipodystrophy.
Fischer-Posovszky P, Hebestreit H, Hofmann AK, Strauss G, Möller P, Debatin KM, Wabitsch M
J Clin Endocrinol Metab. 2006
PubMed ID: 16368755
Influence of TRP53 status on FAS membrane localization, CFLAR (c-FLIP) ubiquitinylation, and sensitivity of GC-2spd (ts) cells to undergo FAS-mediated apoptosis.
Chandrasekaran Y, McKee CM, Ye Y, Richburg JH
Biol Reprod. 2006
PubMed ID: 16306425
Involvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseases.
Nishimura H, Strominger JL
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16492738
Dendritic cell apoptosis in the maintenance of immune tolerance.
Chen M, Wang YH, Wang Y, Huang L, Sandoval H, Liu YJ, Wang J
Science. 2006
PubMed ID: 16497935
A polymorphism in FAS gene promoter associated with increased risk of nasopharyngeal carcinoma and correlated with anti-nuclear autoantibodies induction.
Bel Hadj Jrad B, Mahfouth W, Bouaouina N, Gabbouj S, Ahmed SB, Ltaïef M, Jalbout M, Chouchane L
Cancer Lett. 2006
PubMed ID: 16473667
B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation.
William J, Euler C, Primarolo N, Shlomchik MJ
J Immunol. 2006
PubMed ID: 16455970
Abnormal Fas/FasL and caspase-3-mediated apoptotic signaling pathways of T lymphocyte subset in patients with systemic lupus erythematosus.
Xue C, Lan-Lan W, Bei C, Jie C, Wei-Hua F
Cell Immunol. 2006
PubMed ID: 16808908
A functional role of flip in conferring resistance of Crohn's disease lamina propria lymphocytes to FAS-mediated apoptosis.
Monteleone I, Monteleone G, Fina D, Caruso R, Petruzziello C, Calabrese E, Biancone L, Pallone F
Gastroenterology. 2006
PubMed ID: 16472594
Estrous cycle dependent changes in expression and distribution of Fas, Fas ligand, Bcl-2, Bax, and pro- and active caspase-3 in the rat ovary.
Slot KA, Voorendt M, de Boer-Brouwer M, van Vugt HH, Teerds KJ
J Endocrinol. 2006
PubMed ID: 16461545
Study of Fas (CD95) and FasL (CD178) polymorphisms in liver transplant recipients.
Marín LA, Muro M, Moya-Quiles MR, Miras M, Minguela A, Bermejo J, Sanchez-Bueno F, Parrilla P, Alvarez-López MR
Tissue Antigens. 2006
PubMed ID: 16441482
Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB.
Okamoto K, Fujisawa J, Reth M, Yonehara S
Genes Cells. 2006
PubMed ID: 16436054
Fas costimulation of naive CD4 T cells is controlled by NF-kappaB signaling and caspase activity.
Maksimow M, Söderström TS, Jalkanen S, Eriksson JE, Hänninen A
J Leukoc Biol. 2006
PubMed ID: 16330535
Involvement of Fas and FasL in Ectromelia virus-induced apoptosis in mouse brain.
Krzyzowska M, Cymerys J, Winnicka A, Niemiałtowski M
Virus Res. 2006
PubMed ID: 16169110
Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis.
Ivanov VN, Ronai Z, Hei TK
J Biol Chem. 2006
PubMed ID: 16306044
Modulation of Fas-mediated apoptosis by lipid rafts in T lymphocytes.
Legembre P, Daburon S, Moreau P, Moreau JF, Taupin JL
J Immunol. 2006
PubMed ID: 16393952
Enhancement of bio-protective functions by low dose/dose-rate radiation.
Sakai K, Nomura T, Ina Y
Dose Response. 2006
PubMed ID: 18648588
A polymorphism of C-to-T substitution at -31 IL1B is associated with the risk of advanced gastric adenocarcinoma in a Japanese population.
Ikehara SK, Ikehara Y, Matsuo K, Hirose K, Niwa T, Ito H, Ito S, Kodera Y, Yamamura Y, Nakanishi H, Tatematsu M, Tajima K
J Hum Genet. 2006
PubMed ID: 17006606
Concentrations of soluble Fas and soluble Fas ligand as indicators of programmed cell death among patients coinfected with Human Immunodeficiency Virus and Hepatitis C Virus.
Lapinski TW, Jaroszewicz J, Wiercinska-Drapalo A
Viral Immunol. 2006
PubMed ID: 16987075
Polymorphisms of fas gene: relationship with Alzheimer's disease and cognitive decline.
Chiappelli M, Nasi M, Cossarizza A, Porcellini E, Tumini E, Pinti M, Troiano L, Franceschi M, Licastro F
Dement Geriatr Cogn Disord. 2006
PubMed ID: 16921240
Associations between soluble APO-1 (Fas/CD95) concentrations and hematopoietic activity in healthy women.
Choi JW
Acta Haematol. 2006
PubMed ID: 16914910
Fas gene promoter -670 polymorphism in gynecological cancer.
Ueda M, Terai Y, Kanda K, Kanemura M, Takehara M, Yamaguchi H, Nishiyama K, Yasuda M, Ueki M
Int J Gynecol Cancer. 2006
PubMed ID: 16515587
Sexual dimorphism in immune response genes as a function of puberty.
Lamason R, Zhao P, Rawat R, Davis A, Hall JC, Chae JJ, Agarwal R, Cohen P, Rosen A, Hoffman EP, Nagaraju K
BMC Immunol. 2006
PubMed ID: 16504066
CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase.
Wei L, Sun XJ, Wang Z, Chen Q
Arthritis Res Ther. 2006
PubMed ID: 16469115
Genetic deletion of fas receptors or Fas ligands does not reduce infarct size after acute global ischemia-reperfusion in isolated mouse heart.
Tekin D, Xi L, Kukreja RC
Cell Biochem Biophys. 2006
PubMed ID: 16456239
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A
Am J Hum Genet. 2006
PubMed ID: 16385451
A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice.
Komori H, Furukawa H, Mori S, Ito MR, Terada M, Zhang MC, Ishii N, Sakuma N, Nose M, Ono M
J Immunol. 2006
PubMed ID: 16365433
Granzyme B, a new player in activation-induced cell death, is down-regulated by vasoactive intestinal peptide in Th2 but not Th1 effectors.
Sharma V, Delgado M, Ganea D
J Immunol. 2006
PubMed ID: 16365400
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
c-Flip expression and function in fetal mouse gonocytes.
Giampietri C, Petrungaro S, Klinger FG, Coluccia P, Paone A, Vivarelli E, Filippini A, De Cesaris P, De Felici M, Ziparo E
FASEB J. 2006
PubMed ID: 16263940
Atrophy of mesenteric lymph nodes in experimental Chagas' disease: differential role of Fas/Fas-L and TNFRI/TNF pathways.
de Meis J, Mendes-da-Cruz DA, Farias-de-Oliveira DA, Corrêa-de-Santana E, Pinto-Mariz F, Cotta-de-Almeida V, Bonomo A, Savino W
Microbes Infect. 2006
PubMed ID: 16239119
Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL.
Peng Y, Gallagher SF, Haines K, Baksh K, Murr MM
J Surg Res. 2006
PubMed ID: 16154149
Toll-like receptors 2 and 4 are differentially involved in Fas dependent apoptosis in Peyer's patch and the liver at an early stage after bile duct ligation in mice.
Ogawa A, Tagawa T, Nishimura H, Yajima T, Abe T, Arai T, Taniguchi M, Takeda K, Akira S, Nimura Y, Yoshikai Y
Gut. 2006
PubMed ID: 16118350
Control of neuronal branching by the death receptor CD95 (Fas/Apo-1).
Zuliani C, Kleber S, Klussmann S, Wenger T, Kenzelmann M, Schreglmann N, Martinez A, del Rio JA, Soriano E, Vodrazka P, Kuner R, Groene HJ, Herr I, Krammer PH, Martin-Villalba A
Cell Death Differ. 2006
PubMed ID: 16003386
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling.
Piazzolla D, Meissl K, Kucerova L, Rubiolo C, Baccarini M
J Cell Biol. 2005
PubMed ID: 16365167
Complement-dependent apoptosis and inflammatory gene changes in murine lupus cerebritis.
Alexander JJ, Jacob A, Bao L, Macdonald RL, Quigg RJ
J Immunol. 2005
PubMed ID: 16339572
CD8 T cell-mediated lung damage in response to the extracellular pathogen pneumocystis is dependent on MHC class I expression by radiation-resistant lung cells.
Meissner NN, Lund FE, Han S, Harmsen A
J Immunol. 2005
PubMed ID: 16339567
Cutting edge: Foxj1 protects against autoimmunity and inhibits thymocyte egress.
Srivatsan S, Peng SL
J Immunol. 2005
PubMed ID: 16339515
Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.
Perl M, Chung CS, Lomas-Neira J, Rachel TM, Biffl WL, Cioffi WG, Ayala A
Am J Pathol. 2005
PubMed ID: 16314469
Interaction of Fas ligand and Fas expressed on osteoclast precursors increases osteoclastogenesis.
Park H, Jung YK, Park OJ, Lee YJ, Choi JY, Choi Y
J Immunol. 2005
PubMed ID: 16301623
Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1).
Shimizu S, Sugiyama N, Masutani K, Sadanaga A, Miyazaki Y, Inoue Y, Akahoshi M, Katafuchi R, Hirakata H, Harada M, Hamano S, Nakashima H, Yoshida H
J Immunol. 2005
PubMed ID: 16301622
Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-prone mice.
Pérez de Lema G, Maier H, Franz TJ, Escribese M, Chilla S, Segerer S, Camarasa N, Schmid H, Banas B, Kalaydjiev S, Busch DH, Pfeffer K, Mampaso F, Schlöndorff D, Luckow B
J Am Soc Nephrol. 2005
PubMed ID: 16267157
Characterization of the lipolytic pathways that mediate free fatty acid release during Fas/CD95-induced apoptosis.
Iturralde M, Pardo J, Lacasa E, Barrio G, Alava MA, Piñeiro A, Naval J, Anel A
Apoptosis. 2005
PubMed ID: 16215685
Modulation of Fas-induced apoptosis by p75 neurotrophin receptor in a human neuroblastoma cell line.
Giraud S, Lautrette C, Bessette B, Decourt C, Mathonnet M, Jauberteau MO
Apoptosis. 2005
PubMed ID: 16215672
Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia.
Nolsøe RL, Kelly JA, Pociot F, Moser KL, Kristiansen OP, Mandrup-Poulsen T, Harley JB
Genes Immun. 2005
PubMed ID: 16163374
Cross talk between growth factors and viral and cellular factors alters neuronal signaling pathways: implication for HIV-associated dementia.
Peruzzi F, Bergonzini V, Aprea S, Reiss K, Sawaya BE, Rappaport J, Amini S, Khalili K
Brain Res Brain Res Rev. 2005
PubMed ID: 15936090
Expression of Fas and Fas-ligand and analysis of argyrophilic nucleolar organizer regions in squamous cell carcinoma: relationships with tumor stage and grade, and apoptosis.
Guler N, Uckan S, Celik I, Oznurlu Y, Uckan D
Int J Oral Maxillofac Surg. 2005
PubMed ID: 15907374
High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors.
Hausl C, Ahmad RU, Sasgary M, Doering CB, Lollar P, Richter G, Schwarz HP, Turecek PL, Reipert BM
Blood. 2005
PubMed ID: 16091456
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.
Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, Christensen SR, Shlomchik MJ, Viglianti GA, Rifkin IR, Marshak-Rothstein A
J Exp Med. 2005
PubMed ID: 16260486
Interleukin-10 and Fas polymorphisms and susceptibility for (pre)neoplastic cervical disease.
Zoodsma M, Nolte IM, Schipper M, Oosterom E, van der Steege G, de Vries EG, Te Meerman GJ, van der Zee AG
Int J Gynecol Cancer. 2005
PubMed ID: 16343245
The -670A > G polymorphism in the promoter region of the FAS gene is associated with necrosis in periportal areas in patients with chronic hepatitis C.
Aguilar-Reina J, Ruiz-Ferrer M, Pizarro MA, Antiñolo G
J Viral Hepat. 2005
PubMed ID: 16255757
Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis.
Hövelmeyer N, Hao Z, Kranidioti K, Kassiotis G, Buch T, Frommer F, von Hoch L, Kramer D, Minichiello L, Kollias G, Lassmann H, Waisman A
J Immunol. 2005
PubMed ID: 16237080
Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains.
Ma L, Chan KW, Trendell-Smith NJ, Wu A, Tian L, Lam AC, Chan AK, Lo CK, Chik S, Ko KH, To CK, Kam SK, Li XS, Yang CH, Leung SY, Ng MH, Stott DI, MacPherson GG, Huang FP
Eur J Immunol. 2005
PubMed ID: 16224814
Anti-apoptosis effects of oxymatrine protect the liver from warm ischemia reperfusion injury in rats.
Jiang H, Meng F, Li J, Sun X
World J Surg. 2005
PubMed ID: 16222447
Interferon-beta: a therapeutic for autoimmune lupus in MRL-Faslpr mice.
Schwarting A, Paul K, Tschirner S, Menke J, Hansen T, Brenner W, Kelley VR, Relle M, Galle PR
J Am Soc Nephrol. 2005
PubMed ID: 16221871
B lymphocytes mediate Fas-dependent cytotoxicity in MRL/lpr mice.
Bonardelle D, Benihoud K, Kiger N, Bobé P
J Leukoc Biol. 2005
PubMed ID: 16204618
Estrogens up-regulate the Fas/FasL apoptotic pathway in lactotropes.
Jaita G, Candolfi M, Zaldivar V, Zárate S, Ferrari L, Pisera D, Castro MG, Seilicovich A
Endocrinology. 2005
PubMed ID: 16099864
Fas-independent mitochondrial damage triggers cardiomyocyte death after ischemia-reperfusion.
Gomez L, Chavanis N, Argaud L, Chalabreysse L, Gateau-Roesch O, Ninet J, Ovize M
Am J Physiol Heart Circ Physiol. 2005
PubMed ID: 16006549
Mechanism of counterattack of colorectal cancer cell by Fas/Fas ligand system.
Zhu Q, Liu JY, Xu HW, Yang CM, Zhang AZ, Cui Y, Wang HB
World J Gastroenterol. 2005
PubMed ID: 16273638
Inhibition of the transcription factor Yin Yang 1 activity by S-nitrosation.
Hongo F, Garban H, Huerta-Yepez S, Vega M, Jazirehi AR, Mizutani Y, Miki T, Bonavida B
Biochem Biophys Res Commun. 2005
PubMed ID: 16143308
Treatment with a laminin-derived peptide suppresses lupus nephritis.
Amital H, Heilweil M, Ulmansky R, Szafer F, Bar-Tana R, Morel L, Foster MH, Mostoslavsky G, Eilat D, Pizov G, Naparstek Y
J Immunol. 2005
PubMed ID: 16210660
The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation.
Fortner KA, Budd RC
J Immunol. 2005
PubMed ID: 16177078
Genetic polymorphisms of Fas (CD95) and Fas ligand (CD178) influence the rise in CD4+ T cell count after antiretroviral therapy in drug-naïve HIV-positive patients.
Nasi M, Pinti M, Bugarini R, Troiano L, Lugli E, Bellodi C, Mussini C, Borghi V, Trenti T, Balli F, Esposito R, Cossarizza A
Immunogenetics. 2005
PubMed ID: 16158329
FAS promoter polymorphisms correlate with activity grade in hepatitis C patients.
McIlroy D, Théodorou I, Ratziu V, Vidaud D, Pellet P, Debré P, Poynard T
Eur J Gastroenterol Hepatol. 2005
PubMed ID: 16148554
Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells.
De Paepe ME, Mao Q, Chao Y, Powell JL, Rubin LP, Sharma S
Am J Physiol Lung Cell Mol Physiol. 2005
PubMed ID: 16148053
Genetic polymorphisms of FAS and FASL (CD95/CD95L) genes in cervical carcinogenesis: An analysis of haplotype and gene-gene interaction.
Lai HC, Lin WY, Lin YW, Chang CC, Yu MH, Chen CC, Chu TY
Gynecol Oncol. 2005
PubMed ID: 15996722
In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice.
Wesche-Soldato DE, Chung CS, Lomas-Neira J, Doughty LA, Gregory SH, Ayala A
Blood. 2005
PubMed ID: 15941915
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung.
Matute-Bello G, Lee JS, Liles WC, Frevert CW, Mongovin S, Wong V, Ballman K, Sutlief S, Martin TR
J Immunol. 2005
PubMed ID: 16148156
Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines.
Guo Z, Zhang M, Tang H, Cao X
Blood. 2005
PubMed ID: 15941911
Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice.
Chugh P, Matta H, Schamus S, Zachariah S, Kumar A, Richardson JA, Smith AL, Chaudhary PM
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16120683
Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease.
Landau AM, Luk KC, Jones ML, Siegrist-Johnstone R, Young YK, Kouassi E, Rymar VV, Dagher A, Sadikot AF, Desbarats J
J Exp Med. 2005
PubMed ID: 16129703
Prognostic impact of FAS/CD95/APO-1 in urothelial cancers: decreased expression of Fas is associated with disease progression.
Yamana K, Bilim V, Hara N, Kasahara T, Itoi T, Maruyama R, Nishiyama T, Takahashi K, Tomita Y
Br J Cancer. 2005
PubMed ID: 16091761
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Interleukin-9 stimulates the production of interleukin-5 in CD4+ T cells.
Poulin LF, Habran C, Stordeur P, Goldman M, McKenzie A, Van Snick J, Renauld JC, Braun MY
Eur Cytokine Netw. 2005
PubMed ID: 16266865
Polymorphism of Fas and Fas ligand in preterm premature rupture of membranes in singleton pregnancies.
Fuks A, Parton LA, Polavarapu S, Netta D, Strassberg S, Godi I, Hsu CD
Am J Obstet Gynecol. 2005
PubMed ID: 16157125
Increased expression of apoptosis-associated proteins in puromycin aminonucleoside nephrosis.
Viera NT, Pedreáñez A, Romero MJ, Rincón JC, Mosquera JA
Invest Clin. 2005
PubMed ID: 16152783
CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses.
Barrington RA, Zhang M, Zhong X, Jonsson H, Holodick N, Cherukuri A, Pierce SK, Rothstein TL, Carroll MC
J Immunol. 2005
PubMed ID: 16116172
The role of Fas ligand as an effector molecule in corneal graft rejection.
Stuart PM, Yin X, Plambeck S, Pan F, Ferguson TA
Eur J Immunol. 2005
PubMed ID: 16114107
Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice.
Sarang Z, Molnár P, Németh T, Gomba S, Kardon T, Melino G, Cotecchia S, Fésüs L, Szondy Z
Hepatology. 2005
PubMed ID: 16108039
Characterization of soluble FAS, FAS ligand and tumour necrosis factor-alpha in patients with chronic HCV infection.
Raghuraman S, Abraham P, Daniel HD, Ramakrishna BS, Sridharan G
J Clin Virol. 2005
PubMed ID: 16087126
The role of Fas-mediated apoptosis in otitis media: observations in the lpr/lpr mouse.
Rivkin AZ, Palacios SD, Pak K, Bennett T, Ryan AF
Hear Res. 2005
PubMed ID: 15978756
Fast neutrons-induced apoptosis is Fas-independent in lymphoblastoid cells.
Fischer B, Benzina S, Jeannequin P, Dufour P, Bergerat JP, Denis JM, Gueulette J, Bischoff PL
Biochem Biophys Res Commun. 2005
PubMed ID: 16018969
Fas binding to calmodulin regulates apoptosis in osteoclasts.
Wu X, Ahn EY, McKenna MA, Yeo H, McDonald JM
J Biol Chem. 2005
PubMed ID: 15965236
CD47 augments Fas/CD95-mediated apoptosis.
Manna PP, Dimitry J, Oldenborg PA, Frazier WA
J Biol Chem. 2005
PubMed ID: 15917238
Demonstration of autoimmunity in the tight skin-2 mouse: a model for scleroderma.
Gentiletti J, McCloskey LJ, Artlett CM, Peters J, Jimenez SA, Christner PJ
J Immunol. 2005
PubMed ID: 16081813
Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells.
Dimberg LY, Dimberg AI, Ivarsson K, Strömberg T, Osterborg A, Nilsson K, Oberg F, Jernberg Wiklund H
Blood. 2005
PubMed ID: 15860671
Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis.
Verbsky J, Majerus PW
J Biol Chem. 2005
PubMed ID: 15967797
[Genetic polymorphisms of apoptosis-associated genes FAS and FASL and risk of colorectal cancer]
Yang S, Miao XP, Zhang XM, Sun T, Qu SN, Xiong P, Ye YJ, Guo YL, Tan W, Wang S, Lin DX
Zhonghua Yi Xue Za Zhi. 2005
PubMed ID: 16313826
Evidence for involvement of p59fyn in fasting-induced thymic involution.
Nishio H, Takase I, Fukunishi S, Takagi T, Tamura A, Miyazaki T, Suzuki K
Scand J Immunol. 2005
PubMed ID: 16101815
The role of Fas in the immune system biology of IL-2R alpha knockout mice: interplay among regulatory T cells, inflammation, hemopoiesis, and apoptosis.
Sharma R, Bagavant H, Jarjour WN, Sung SS, Ju ST
J Immunol. 2005
PubMed ID: 16034141
Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis.
Bao L, Osawe I, Haas M, Quigg RJ
J Immunol. 2005
PubMed ID: 16034139
NF-kappaB regulates Fas-mediated apoptosis in HIV-associated nephropathy.
Ross MJ, Martinka S, D'Agati VD, Bruggeman LA
J Am Soc Nephrol. 2005
PubMed ID: 15975999
Differential expression of LFA-3, Fas and MHC Class I on Ad5- and Ad12-transformed human cells and their susceptibility to lymphokine-activated killer (LAK) cells.
Bottley G, Cook GP, Meade JL, Holt JR, Hoeben RC, Blair GE
Virology. 2005
PubMed ID: 15963548
Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.
Matarrese P, Malorni W
Cell Death Differ. 2005
PubMed ID: 15818415
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus.
Christensen SR, Kashgarian M, Alexopoulou L, Flavell RA, Akira S, Shlomchik MJ
J Exp Med. 2005
PubMed ID: 16027240
Restraint of B cell activation by Foxj1-mediated antagonism of NF-kappa B and IL-6.
Lin L, Brody SL, Peng SL
J Immunol. 2005
PubMed ID: 16002694
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.
Martin LJ, Chen K, Liu Z
J Neurosci. 2005
PubMed ID: 16000635
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria.
Gressner O, Schilling T, Lorenz K, Schulze Schleithoff E, Koch A, Schulze-Bergkamen H, Lena AM, Candi E, Terrinoni A, Catani MV, Oren M, Melino G, Krammer PH, Stremmel W, Müller M
EMBO J. 2005
PubMed ID: 15944736
[The relationship between expression of fas mRNA and apoptosis after traumatic brain injury in rats and the role of GM-1 in protecting the brain].
Liu QJ, Zhu J, Zhao JX, Li JM, Fu AJ, Liu G
Sichuan Da Xue Xue Bao Yi Xue Ban. 2005
PubMed ID: 16078565
FAS/FAS ligand ratio: a marker of oxaliplatin-based intrinsic and acquired resistance in advanced colorectal cancer.
Nadal C, Maurel J, Gallego R, Castells A, Longarón R, Marmol M, Sanz S, Molina R, Martin-Richard M, Gascón P
Clin Cancer Res. 2005
PubMed ID: 16000573
Fas ligand but not complement is critical for control of experimental Staphylococcus aureus Endophthalmitis.
Engelbert M, Gilmore MS
Invest Ophthalmol Vis Sci. 2005
PubMed ID: 15980239
Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.
Dohrman A, Russell JQ, Cuenin S, Fortner K, Tschopp J, Budd RC
J Immunol. 2005
PubMed ID: 15972663
HIV type 1 glycoprotein 120 inhibits human B cell chemotaxis to CXC chemokine ligand (CXCL) 12, CC chemokine ligand (CCL)20, and CCL21.
Badr G, Borhis G, Treton D, Moog C, Garraud O, Richard Y
J Immunol. 2005
PubMed ID: 15972662
Mousepox conjunctivitis: the role of Fas/FasL-mediated apoptosis of epithelial cells in virus dissemination.
Krzyzowska M, Polanczyk M, Bas M, Cymerys J, Schollenberger A, Chiodi F, Niemialtowski M
J Gen Virol. 2005
PubMed ID: 15958680
Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8+-T-cell escape variants of influenza virus.
Price GE, Huang L, Ou R, Zhang M, Moskophidis D
J Virol. 2005
PubMed ID: 15956596
Selective up-regulation of caspase-3 gene expression following TCR engagement.
Sabbagh L, Bourbonnière M, Sékaly RP, Cohen LY
Mol Immunol. 2005
PubMed ID: 15950730
cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells.
Smyth LA, Brady HJ
Hypertension. 2005
PubMed ID: 15911745
Fas gene promoter -670 polymorphism (A/G) is associated with cervical carcinogenesis.
Ueda M, Hung YC, Terai Y, Yamaguchi H, Saito J, Nunobiki O, Noda S, Ueki M
Gynecol Oncol. 2005
PubMed ID: 15894356
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
Alexander JJ, Zwingmann C, Quigg R
Neurochem Int. 2005
PubMed ID: 15893408
Fas-mediated death and sensory adaptation limit the pathogenic potential of autoreactive T cells after strong antigenic stimulation.
Ryan KR, McCue D, Anderton SM
J Leukoc Biol. 2005
PubMed ID: 15817704
Action and mechanism of Fas and Fas ligand in immune escape of gallbladder carcinoma.
Xu LN, Zou SQ, Wang JM
World J Gastroenterol. 2005
PubMed ID: 15968727
P-glycoprotein is not involved in pathway of anti-Fas/Fas-induced apoptosis in KBv200 cells.
Wu QL, Wu XP, Liang YJ, Chen LM, Ding Y, Fu LW
World J Gastroenterol. 2005
PubMed ID: 15962371
Serial in vivo loss and in vitro gain of Fas expression and function in human cancerous pancreatic duct cells.
Radfar S, Davrinche C, Hollande E
Int J Cancer. 2005
PubMed ID: 15688389
[The expression and significance of Fas/FasL in nasal polyps tissue].
Li Q, Ming W, Zhang H, Chen X, Jian J, Zhang D
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005
PubMed ID: 16124644
Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer.
Zhang X, Miao X, Sun T, Tan W, Qu S, Xiong P, Zhou Y, Lin D
J Med Genet. 2005
PubMed ID: 15937082
Fas polymorphisms influence susceptibility to autoimmune hepatitis.
Hiraide A, Imazeki F, Yokosuka O, Kanda T, Kojima H, Fukai K, Suzuki Y, Hata A, Saisho H
Am J Gastroenterol. 2005
PubMed ID: 15929764
Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection.
Flórido M, Pearl JE, Solache A, Borges M, Haynes L, Cooper AM, Appelberg R
Infect Immun. 2005
PubMed ID: 15908387
Induction of stable mixed chimerism by embryonic stem cells requires functional Fas/FasL engagement.
Fabricius D, Bonde S, Zavazava N
Transplantation. 2005
PubMed ID: 15880040
Cutting edge: CD95 maintains effector T cell homeostasis in chronic immune activation.
Arens R, Baars PA, Jak M, Tesselaar K, van der Valk M, van Oers MH, van Lier RA
J Immunol. 2005
PubMed ID: 15879081
CD95 capping is ROCK-dependent and dispensable for apoptosis.
Söderström TS, Nyberg SD, Eriksson JE
J Cell Sci. 2005
PubMed ID: 15855233
[Expression of Fas antigen and ligand, placental growth factor in placenta of pregnant women with pre-eclampsia]
Yue XY, Zhang X, Cui SH, Wang XQ
Zhonghua Fu Chan Ke Za Zhi. 2005
PubMed ID: 15938782
SOD-1 inhibits FAS expression in cortex of APP transgenic mice.
Chen Z, Duan RS, Lepécheur M, Paly E, London J, Zhu J
Apoptosis. 2005
PubMed ID: 15909112
Fas has a role in cerebral malaria, but not in proliferation or exclusion of the murine parasite in mice.
Ohno T, Kobayashi F, Nishimura M
Immunogenetics. 2005
PubMed ID: 15900502
The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleukin-1be
Priceputu E, Rodrigue I, Chrobak P, Poudrier J, Mak TW, Hanna Z, Hu C, Kay DG, Jolicoeur P
J Virol. 2005
PubMed ID: 15858021
HIV-1 trans-activator of transcription substitutes for oxidative signaling in activation-induced T cell death.
Gülow K, Kaminski M, Darvas K, Süss D, Li-Weber M, Krammer PH
J Immunol. 2005
PubMed ID: 15843521
Polymorphisms in the promoter regions of FAS and FASL genes as candidate genetic factors conferring susceptibility to endometriosis.
Fernández RM, Noval JA, García-Lozano JC, Borrego S, Moliní JL, Antiñolo G
Int J Mol Med. 2005
PubMed ID: 15806311
p53 is required for spontaneous autoantibody production in B6/lpr lupus mice.
Kuan AP, Cohen PL
Eur J Immunol. 2005
PubMed ID: 15789337
Anti-CD3 induces bi-phasic apoptosis in murine intestinal epithelial cells: possible involvement of the Fas/Fas ligand system in different T cell compartments.
Miura N, Yamamoto M, Fukutake M, Ohtake N, Iizuka S, Ishige A, Sasaki H, Fukuda K, Yamamoto T, Hayakawa S
Int Immunol. 2005
PubMed ID: 15778290
Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation.
Zielinski CE, Jacob SN, Bouzahzah F, Ehrlich BE, Craft J
J Immunol. 2005
PubMed ID: 15814741
Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.
Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH
Nature. 2005
PubMed ID: 15829968
Resistance to activation-induced cell death and bystander cytotoxicity via the Fas/Fas ligand pathway are implicated in the pathogenesis of cutaneous T cell lymphomas.
Ni X, Zhang C, Talpur R, Duvic M
J Invest Dermatol. 2005
PubMed ID: 15816832
Activation of the lectin pathway in murine lupus nephritis.
Trouw LA, Seelen MA, Duijs JM, Wagner S, Loos M, Bajema IM, van Kooten C, Roos A, Daha MR
Mol Immunol. 2005
PubMed ID: 15781117
CD8-mediated protection against Ebola virus infection is perforin dependent.
Gupta M, Greer P, Mahanty S, Shieh WJ, Zaki SR, Ahmed R, Rollin PE
J Immunol. 2005
PubMed ID: 15778381
Fas polymorphisms are associated with the presence of anti-ganglioside antibodies in Guillain-Barre syndrome.
Geleijns K, Laman JD, van Rijs W, Tio-Gillen AP, Hintzen RQ, van Doorn PA, Jacobs BC
J Neuroimmunol. 2005
PubMed ID: 15748958
CD95 and TRAF2 promote invasiveness of pancreatic cancer cells.
Trauzold A, Röder C, Sipos B, Karsten K, Arlt A, Jiang P, Martin-Subero JI, Siegmund D, Müerköster S, Pagerols-Raluy L, Siebert R, Wajant H, Kalthoff H
FASEB J. 2005
PubMed ID: 15670977
Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues.
Gosmain Y, Dif N, Berbe V, Loizon E, Rieusset J, Vidal H, Lefai E
J Lipid Res. 2005
PubMed ID: 15627654
Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages.
Medan D, Wang L, Toledo D, Lu B, Stehlik C, Jiang BH, Shi X, Rojanasakul Y
J Cell Physiol. 2005
PubMed ID: 15368542
The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability.
Henkler F, Behrle E, Dennehy KM, Wicovsky A, Peters N, Warnke C, Pfizenmaier K, Wajant H
J Cell Biol. 2005
PubMed ID: 15795317
Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy.
Gajate C, Mollinedo F
J Biol Chem. 2005
PubMed ID: 15659383
Correlation of CD95 and soluble CD95 expression with acute rejection status of liver transplantation.
Wang YL, Zhang YY, Li G, Tang ZQ, Zhou YL, Zhu ZJ, Yao Z
World J Gastroenterol. 2005
PubMed ID: 15786554
Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.
Clemons NJ, Buzzard K, Steel R, Anderson RL
J Biol Chem. 2005
PubMed ID: 15632129
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.
Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, Griffith TS, Green DR, Schoenberger SP
Nature. 2005
PubMed ID: 15744305
Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset.
Ishikawa K, Funayama T, Ohde H, Inagaki Y, Mashima Y
Jpn J Ophthalmol. 2005
PubMed ID: 15838728
Relationship of acute lung inflammatory injury to Fas/FasL system.
Neff TA, Guo RF, Neff SB, Sarma JV, Speyer CL, Gao H, Bernacki KD, Huber-Lang M, McGuire S, Hoesel LM, Riedemann NC, Beck-Schimmer B, Zetoune FS, Ward PA
Am J Pathol. 2005
PubMed ID: 15743781
An A > G polymorphism at position -670 in the Fas (TNFRSF6) gene in pregnant women with pre-eclampsia and intrauterine growth restriction.
Sziller I, Nguyen D, Halmos A, Hupuczi P, Papp Z, Witkin SS
Mol Hum Reprod. 2005
PubMed ID: 15695771
Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes.
Uriarte SM, Joshi-Barve S, Song Z, Sahoo R, Gobejishvili L, Jala VR, Haribabu B, McClain C, Barve S
Cell Death Differ. 2005
PubMed ID: 15665818
Characterization of signaling pathways leading to Fas expression induced by TNF-alpha: pivotal role of NF-kappaB.
Starace D, Riccioli A, D'Alessio A, Giampietri C, Petrungaro S, Galli R, Filippini A, Ziparo E, De Cesaris P
FASEB J. 2005
PubMed ID: 15601669
Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells.
Mezosi E, Wang SH, Utsugi S, Bajnok L, Bretz JD, Gauger PG, Thompson NW, Baker JR
Mol Endocrinol. 2005
PubMed ID: 15563545
Bile salt-induced apoptosis in human colon cancer cell lines involves the mitochondrial transmembrane potential but not the CD95 (Fas/Apo-1) receptor.
Wachs FP, Krieg RC, Rodrigues CM, Messmann H, Kullmann F, Knüchel-Clarke R, Schölmerich J, Rogler G, Schlottmann K
Int J Colorectal Dis. 2005
PubMed ID: 15365741
Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission.
Matarrese P, Tinari A, Mormone E, Bianco GA, Toscano MA, Ascione B, Rabinovich GA, Malorni W
J Biol Chem. 2005
PubMed ID: 15556941
Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study.
Annells MF, Hart PH, Mullighan CG, Heatley SL, Robinson JS, McDonald HM
BMC Pregnancy Childbirth. 2005
PubMed ID: 15723707
Fas/Fas-Ligand pathway is impaired in patients with type 2 diabetes. Influence of hypertension and insulin resistance.
Cosson E, Bringuier AF, Paries J, Guillot R, Vaysse J, Attali JR, Feldmann G, Valensi P
Diabetes Metab. 2005
PubMed ID: 15803113
Altered trafficking of Fas and subsequent resistance to Fas-mediated apoptosis occurs by a wild-type p53 independent mechanism in esophageal adenocarcinoma.
Mahidhara RS, Queiroz De Oliveira PE, Kohout J, Beer DG, Lin J, Watkins SC, Robbins PD, Hughes SJ
J Surg Res. 2005
PubMed ID: 15680394
Analysis of marginal zone B cell development in the mouse with limited B cell diversity: role of the antigen receptor signals in the recruitment of B cells to the marginal zone.
Kanayama N, Cascalho M, Ohmori H
J Immunol. 2005
PubMed ID: 15661902
The role of p53 and Fas in a model of acute murine graft-versus-host disease.
Yada S, Takamura N, Inagaki-Ohara K, O'leary MK, Wasem C, Brunner T, Green DR, Lin T, Pinkoski MJ
J Immunol. 2005
PubMed ID: 15661885
Fas and Fas ligand in cyst fluids, serum and tumors of patients with benign and (borderline) malignant ovarian tumors.
Arts HJ, de Jong S, Hollema H, Ten Hoor KA, de Vries EG, van der Zee AG
Int J Oncol. 2005
PubMed ID: 15645122
Cross-Talk between Fas/Fas ligand system and nitric oxide in the pathway subserving granulosa cell apoptosis: a possible regulatory mechanism for ovarian follicle atresia.
Chen Q, Yano T, Matsumi H, Osuga Y, Yano N, Xu J, Wada O, Koga K, Fujiwara T, Kugu K, Taketani Y
Endocrinology. 2005
PubMed ID: 15528299
Fas mRNA expression and calcium influx change in H2O2-induced apoptotic hepatocytes in vitro.
Lu QP, Tian L
World J Gastroenterol. 2005
PubMed ID: 15641141
Association of Fas-670 gene polymorphism with inflammatory bowel disease in Chinese patients.
Xia B, Yu YH, Guo QS, Li XY, Jiang L, Li J
World J Gastroenterol. 2005
PubMed ID: 15637757
Effects of human cytomegalovirus infection on apoptosis and expression of apoptosis-regulating factors.
Nie X, Fang F, Li H, Dong Y, Zhou Y, Zhen H, Liu Z, Li G
J Huazhong Univ Sci Technolog Med Sci. 2005
PubMed ID: 16463650
Soluble form of TRAIL, Fas and FasL in the serum of patients with B-CLL.
Jabłońska E, Kiersnowska-Rogowska B, Rogowski F, Parfieńczyk A, Puzewska W, Bukin M
Rocz Akad Med Bialymst. 2005
PubMed ID: 16358967
Relationships of soluble APO-1 (Fas/CD95) concentrations, obesity, and serum lipid parameters in healthy adults.
Choi JW, Kim SK
Ann Clin Lab Sci. 2005
PubMed ID: 16081586
Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis.
Bühling F, Wille A, Röcken C, Wiesner O, Baier A, Meinecke I, Welte T, Pap T
Respir Res. 2005
PubMed ID: 15833141
Preventing human CD8+ cytotoxic T lymphocyte-mediated cytotoxicity against swine endothelial cells by overexpression of human decoy Fas antigen.
Kawamoto K, Tanemura M, Ito T, Uchikoshi F, Shimada K, Nishida T, Matsuda H
Transplant Proc. 2005
PubMed ID: 15808689
4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induces apoptosis in colon cancer partially through the induction of Fas expression.
Sako T, Nakayama Y, Minagawa N, Inoue Y, Onitsuka K, Katsuki T, Tsurudome Y, Shibao K, Hirata K, Nagata N, Ohie S, Kohno K, Itoh H
In Vivo. 2005
PubMed ID: 15796164
FAS and FAS-L expression by tumor cells and lymphocytes in breast carcinomas and their lymph node metastases.
Ioachim HL, Decuseara R, Giancotti F, Dorsett BH
Pathol Res Pract. 2005
PubMed ID: 15792116
A single nucleotide A>G polymorphism at position -670 in the Fas gene promoter: relationship to preterm premature rupture of fetal membranes in multifetal pregnancies.
Kalish RB, Nguyen DP, Vardhana S, Gupta M, Perni SC, Witkin SS
Am J Obstet Gynecol. 2005
PubMed ID: 15672026
Fas and TNFR1, but not cytolytic granule-dependent mechanisms, mediate clearance of murine liver adenoviral infection.
Abougergi MS, Gidner SJ, Spady DK, Miller BC, Thiele DL
Hepatology. 2005
PubMed ID: 15619234
Pregnancy-induced alterations of B cell maturation and survival are differentially affected by Fas and Bcl-2, independently of BcR expression.
Caucheteux SM, Gendron MC, Kanellopoulos-Langevin C
Int Immunol. 2005
PubMed ID: 15569774
Prominent dominant negative effect of a mutant Fas molecule lacking death domain on cell-mediated induction of apoptosis.
Yokota A, Takeuchi E, Iizuka M, Ikegami Y, Takayama H, Shinohara N
Mol Immunol. 2005
PubMed ID: 15488945
Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists.
Park JM, Ng VH, Maeda S, Rest RF, Karin M
J Exp Med. 2004
PubMed ID: 15611291
Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection.
Zelinskyy G, Balkow S, Schimmer S, Schepers K, Simon MM, Dittmer U
Virology. 2004
PubMed ID: 15567431
Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo.
Brown NJ, Hutcheson J, Bickel E, Scatizzi JC, Albee LD, Haines GK, Eslick J, Bradley K, Taricone E, Perlman H
J Immunol. 2004
PubMed ID: 15585886
A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.
Li Q, Ching AK, Chan BC, Chow SK, Lim PL, Ho TC, Ip WK, Wong CK, Lam CW, Lee KK, Chan JY, Chui YL
J Biol Chem. 2004
PubMed ID: 15465831
Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-beta, FAS, and mannose-binding protein C gene polymorphisms in Australian women: Risk of preterm birth.
Annells MF, Hart PH, Mullighan CG, Heatley SL, Robinson JS, Bardy P, McDonald HM
Am J Obstet Gynecol. 2004
PubMed ID: 15592292
IgM monomers accelerate disease manifestations in autoimmune-prone Fas-deficient mice.
Youd ME, Luus L, Corley RB
J Autoimmun. 2004
PubMed ID: 15571927
FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment.
Zacks DN, Zheng QD, Han Y, Bakhru R, Miller JW
Invest Ophthalmol Vis Sci. 2004
PubMed ID: 15557468
Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression.
Wang WH, Grégori G, Hullinger RL, Andrisani OM
Mol Cell Biol. 2004
PubMed ID: 15542843
Interferon-gamma sensitizes osteosarcoma cells to Fas-induced apoptosis by up-regulating Fas receptors and caspase-8.
Inaba H, Glibetic M, Buck S, Ravindranath Y, Kaplan J
Pediatr Blood Cancer. 2004
PubMed ID: 15390286
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells.
Delmas D, Rébé C, Micheau O, Athias A, Gambert P, Grazide S, Laurent G, Latruffe N, Solary E
Oncogene. 2004
PubMed ID: 15480430
SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane.
Siegel RM, Muppidi JR, Sarker M, Lobito A, Jen M, Martin D, Straus SE, Lenardo MJ
J Cell Biol. 2004
PubMed ID: 15557123
Vitamin D3 inhibits fatty acid synthase expression by stimulating the expression of long-chain fatty-acid-CoA ligase 3 in prostate cancer cells.
Qiao S, Tuohimaa P
FEBS Lett. 2004
PubMed ID: 15556626
Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice.
Zhang XK, Gallant S, Molano I, Moussa OM, Ruiz P, Spyropoulos DD, Watson DK, Gilkeson G
J Immunol. 2004
PubMed ID: 15528390
Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness.
Legembre P, Schickel R, Barnhart BC, Peter ME
J Biol Chem. 2004
PubMed ID: 15345718
Involvement of p53 and Fas/CD95 in murine neural progenitor cell response to ionizing irradiation.
Semont A, Nowak EB, Silva Lages C, Mathieu C, Mouthon MA, May E, Allemand I, Millet P, Boussin FD
Oncogene. 2004
PubMed ID: 15361846
Cytochrome c release is required for phosphatidylserine peroxidation during Fas-triggered apoptosis in lung epithelial A549 cells.
Jiang J, Kini V, Belikova N, Serinkan BF, Borisenko GG, Tyurina YY, Tyurin VA, Kagan VE
Lipids. 2004
PubMed ID: 15726829
Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds.
Legembre P, Barnhart BC, Zheng L, Vijayan S, Straus SE, Puck J, Dale JK, Lenardo M, Peter ME
EMBO Rep. 2004
PubMed ID: 15514680
Involvement of tumor necrosis factor-alpha receptor 1 and tumor necrosis factor-related apoptosis-inducing ligand-(TRAIL) receptor-2/DR-5, but not Fas, in graft injury in live-donor liver transplantation.
Tashiro H, Itamoto T, Ohdan H, Arihiro K, Tateaki Y, Nakahara H, Ochi M, Hino H, Mizunuma K, Hara H, Tokita D, Onoe T, Ishiyama K, Mitsuta H, Sugino K, Asahara T
Transpl Int. 2004
PubMed ID: 15502938
Negative correlation between intrahepatic expression of hepatitis C antigens and apoptosis despite high-level expression of Fas and HLA antigens.
Caronia S, McGarvey MJ, Goldin RD, Foster GR
J Viral Hepat. 2004
PubMed ID: 15500551
Impaired apoptosis of lymphocytes derived from patient with decreased expression of caspase-8 results in Alps-like phenotype.
Grzela T, Krauze A, Grzela K, Lazarczyk M, Niderla J, Brawura-Biskupski-Samaha R, Dziunycz P, Milewski L, Korczak-Kowalska G, Kulus M
Int J Mol Med. 2004
PubMed ID: 15492869
Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells.
Song R, Zhou Z, Kim PK, Shapiro RA, Liu F, Ferran C, Choi AM, Otterbein LE
J Biol Chem. 2004
PubMed ID: 15280387
A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation.
Daniel S, Arvelo MB, Patel VI, Longo CR, Shrikhande G, Shukri T, Mahiou J, Sun DW, Mottley C, Grey ST, Ferran C
Blood. 2004
PubMed ID: 15251990
Reactive oxygen species limit neutrophil life span by activating death receptor signaling.
Scheel-Toellner D, Wang K, Craddock R, Webb PR, McGettrick HM, Assi LK, Parkes N, Clough LE, Gulbins E, Salmon M, Lord JM
Blood. 2004
PubMed ID: 15238425
Sapheno-femoral junction pathology: molecular mechanism of saphenous vein incompetence.
Urbanek T, Skop B, Ziaja K, Wilczok T, Wiaderkiewicz R, Pałasz A, Mazurek U, Wielgus E
Clin Appl Thromb Hemost. 2004
PubMed ID: 15497017
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
The relevance of NF-kappaB for CD95 signaling in tumor cells.
Legembre P, Barnhart BC, Peter ME
Cell Cycle. 2004
PubMed ID: 15467462
Negative role of colony-stimulating factor-1 in macrophage, T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice.
Lenda DM, Stanley ER, Kelley VR
J Immunol. 2004
PubMed ID: 15383612
Reduced oncotic necrosis in Fas receptor-deficient C57BL/6J-lpr mice after bile duct ligation.
Gujral JS, Liu J, Farhood A, Jaeschke H
Hepatology. 2004
PubMed ID: 15382126
Fas/FasL-mediated apoptosis in perinatal murine lungs.
De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI
Am J Physiol Lung Cell Mol Physiol. 2004
PubMed ID: 15355863
Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury.
Graham EM, Sheldon RA, Flock DL, Ferriero DM, Martin LJ, O'Riordan DP, Northington FJ
Neurobiol Dis. 2004
PubMed ID: 15350969
Autoimmune lymphoproliferative syndrome with somatic Fas mutations.
Holzelova E, Vonarbourg C, Stolzenberg MC, Arkwright PD, Selz F, Prieur AM, Blanche S, Bartunkova J, Vilmer E, Fischer A, Le Deist F, Rieux-Laucat F
N Engl J Med. 2004
PubMed ID: 15459302
The critical role of Fas-Fas ligand interaction in donor-specific transfusion-induced tolerance to H-Y antigen.
Minagawa R, Okano S, Tomita Y, Kishihara K, Yamada H, Nomoto K, Shimada M, Maehara Y, Sugimachi K, Yoshikai Y, Nomoto K
Transplantation. 2004
PubMed ID: 15385797
Murine male germ cell apoptosis induced by busulfan treatment correlates with loss of c-kit-expression in a Fas/FasL- and p53-independent manner.
Choi YJ, Ok DW, Kwon DN, Chung JI, Kim HC, Yeo SM, Kim T, Seo HG, Kim JH
FEBS Lett. 2004
PubMed ID: 15388331
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions.
Nam YJ, Mani K, Ashton AW, Peng CF, Krishnamurthy B, Hayakawa Y, Lee P, Korsmeyer SJ, Kitsis RN
Mol Cell. 2004
PubMed ID: 15383280
The Tlx gene regulates the timing of neurogenesis in the cortex.
Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP
J Neurosci. 2004
PubMed ID: 15385616
Critical roles for the Fas/Fas ligand system in postinfarction ventricular remodeling and heart failure.
Li Y, Takemura G, Kosai K, Takahashi T, Okada H, Miyata S, Yuge K, Nagano S, Esaki M, Khai NC, Goto K, Mikami A, Maruyama R, Minatoguchi S, Fujiwara T, Fujiwara H
Circ Res. 2004
PubMed ID: 15297380
Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells.
Dalton JE, Howell G, Pearson J, Scott P, Carding SR
J Immunol. 2004
PubMed ID: 15356111
Effects of platelet-derived growth factor and interleukin-10 on Fas/Fas-ligand and Bcl-2/Bax mRNA expression in rat hepatic stellate cells in vitro.
Wang XZ, Zhang SJ, Chen YX, Chen ZX, Huang YH, Zhang LJ
World J Gastroenterol. 2004
PubMed ID: 15309723
Regulation of activation-induced Fas (CD95/Apo-1) ligand expression in T cells by the cyclin B1/Cdk1 complex.
Torgler R, Jakob S, Ontsouka E, Nachbur U, Mueller C, Green DR, Brunner T
J Biol Chem. 2004
PubMed ID: 15215233
Fas signaling is involved in the control of hair follicle response to chemotherapy.
Sharov AA, Siebenhaar F, Sharova TY, Botchkareva NV, Gilchrest BA, Botchkarev VA
Cancer Res. 2004
PubMed ID: 15342414
Renal phenotype is exacerbated in Os and lpr double mutant mice.
Jarad G, Lakhe-Reddy S, Blatnik J, Koepke M, Khan S, El-Meanawy MA, O'Connor AS, Sedor JR, Schelling JR
Kidney Int. 2004
PubMed ID: 15327396
Fas-mediated inhibition of CD4+ T cell priming results in dominance of type 1 CD8+ T cells in the immune response to the contact sensitizer trinitrophenyl.
Martin SF, Dudda JC, Delattre V, Bachtanian E, Leicht C, Burger B, Weltzien HU, Simon JC
J Immunol. 2004
PubMed ID: 15322178
Vulnerability of mouse cortical neurons to doxorubicin-induced apoptosis is strain-dependent and is correlated with mRNAs encoding Fas, Fas-Ligand, and metalloproteinases.
Wetzel M, Tibbitts J, Rosenberg GA, Cunningham LA
Apoptosis. 2004
PubMed ID: 15314293
Evaluation of Fas gene promoter polymorphism in cervical cancer patients.
Dybikowska A, Sliwinski W, Emerich J, Podhajska AJ
Int J Mol Med. 2004
PubMed ID: 15289903
A caspase-8-independent signaling pathway activated by Fas ligation leads to exposure of the Bak N terminus.
Zhang L, Shimizu S, Sakamaki K, Yonehara S, Tsujimoto Y
J Biol Chem. 2004
PubMed ID: 15159409
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases.
Xanthoulea S, Pasparakis M, Kousteni S, Brakebusch C, Wallach D, Bauer J, Lassmann H, Kollias G
J Exp Med. 2004
PubMed ID: 15289505
Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a.
Lin L, Hron JD, Peng SL
Immunity. 2004
PubMed ID: 15308101
CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma.
Mezzanzanica D, Balladore E, Turatti F, Luison E, Alberti P, Bagnoli M, Figini M, Mazzoni A, Raspagliesi F, Oggionni M, Pilotti S, Canevari S
Clin Cancer Res. 2004
PubMed ID: 15297424
Serum levels of soluble molecules associated with evasion of immune surveillance: a study in biliary disease.
Enjoji M, Yamaguchi K, Nakashima M, Ohta S, Kotoh K, Fukushima M, Kuniyoshi M, Tanaka M, Nakamuta M, Watanabe T, Nawata H
Liver Int. 2004
PubMed ID: 15287856
Ongoing myocardial damage in chronic heart failure is related to activated tumor necrosis factor and Fas/Fas ligand system.
Setsuta K, Seino Y, Ogawa T, Ohtsuka T, Seimiya K, Takano T
Circ J. 2004
PubMed ID: 15277733
Loss of LFA-1, but not Mac-1, protects MRL/MpJ-Fas(lpr) mice from autoimmune disease.
Kevil CG, Hicks MJ, He X, Zhang J, Ballantyne CM, Raman C, Schoeb TR, Bullard DC
Am J Pathol. 2004
PubMed ID: 15277234
Type I IFN protects against murine lupus.
Hron JD, Peng SL
J Immunol. 2004
PubMed ID: 15265950
Termination of antigen-specific immunity by CD95 ligand (Fas ligand) and IL-10.
Barreiro R, Luker G, Herndon J, Ferguson TA
J Immunol. 2004
PubMed ID: 15265879
Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase.
Shrivastava P, Pantano C, Watkin R, McElhinney B, Guala A, Poynter ML, Persinger RL, Budd R, Janssen-Heininger Y
Mol Cell Biol. 2004
PubMed ID: 15254243
Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.
Stoletov KV, Terman BI
Biochem Biophys Res Commun. 2004
PubMed ID: 15207703
Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma.
Sun T, Miao X, Zhang X, Tan W, Xiong P, Lin D
J Natl Cancer Inst. 2004
PubMed ID: 15240787
Fas ligand is enriched in the caveolae membrane domains of thymic epithelial cells.
Lalor D, Liu P, Hayashi J
Cell Immunol. 2004
PubMed ID: 15541714
Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.
Cho SM, Kim J, Ryu HJ, Kim JJ, Kim HH, Park JH, Kim HT, Kim KH, Cho HY, Oh B, Park C, Kimm K, Jo I, Lee JE, Shin HD, Lee JK
Hum Immunol. 2004
PubMed ID: 15301860
A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians.
Kovacs P, Harper I, Hanson RL, Infante AM, Bogardus C, Tataranni PA, Baier LJ
Diabetes. 2004
PubMed ID: 15220220
CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells.
Eramo A, Sargiacomo M, Ricci-Vitiani L, Todaro M, Stassi G, Messina CG, Parolini I, Lotti F, Sette G, Peschle C, De Maria R
Eur J Immunol. 2004
PubMed ID: 15214041
Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis.
Jin H, Carrio R, Yu A, Malek TR
J Immunol. 2004
PubMed ID: 15210829
Age-related thymic involution is mediated by Fas on thymic epithelial cells.
Yajima N, Sakamaki K, Yonehara S
Int Immunol. 2004
PubMed ID: 15192051
An increased frequency of autoantibody-inducing CD4+ T cells in pre-diseased lupus-prone mice.
Busser BW, Cancro MP, Laufer TM
Int Immunol. 2004
PubMed ID: 15159378
Generation and selection of an IgG-driven autoimmune repertoire during B-lymphopoiesis in Igmicro-deficient/lpr mice.
Seagal J, Edry E, Naftali H, Melamed D
Int Immunol. 2004
PubMed ID: 15148286
The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95.
Reinehr R, Becker S, Höngen A, Haüssinger D
J Biol Chem. 2004
PubMed ID: 15039424
c-FLIP expression in bladder urothelial carcinomas: its role in resistance to Fas-mediated apoptosis and clinicopathologic correlations.
Korkolopoulou P, Goudopoulou A, Voutsinas G, Thomas-Tsagli E, Kapralos P, Patsouris E, Saetta AA
Urology. 2004
PubMed ID: 15183989
CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice.
Yang JQ, Chun T, Liu H, Hong S, Bui H, Van Kaer L, Wang CR, Singh RR
Eur J Immunol. 2004
PubMed ID: 15162443
Contribution of alphabeta and gammadelta T cells to the generation of primary immunoglobulin G-driven autoimmune response in immunoglobulin- mu-deficient/lpr mice.
Seagal J, Melamed D
Immunology. 2004
PubMed ID: 15147570
CD8+ T cells maintain tolerance to myelin basic protein by 'epitope theft'.
Perchellet A, Stromnes I, Pang JM, Goverman J
Nat Immunol. 2004
PubMed ID: 15146180
Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma.
Murakami M, Sasaki T, Miyata H, Yamasaki S, Kuwahara K, Chayama K
Oncol Rep. 2004
PubMed ID: 15138553
The DNA sequence and comparative analysis of human chromosome 10.
Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L, Steward CA, Sims SK, Jones MC, Searle S, Scott C, Howe K, Hunt SE, Andrews TD, Gilbert JG, Swarbreck D, Ashurst JL, Taylor A, Battles J, Bird CP, Ainscough R, Almeida JP, Ashwell RI, Ambrose KD, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Bates K, Beasley H, Bray-Allen S, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Cahill P, Camire D, Carter NP, Chapman JC, Clark SY, Clarke G, Clee CM, Clegg S, Corby N, Coulson A, Dhami P, Dutta I, Dunn M, Faulkner L, Frankish A, Frankland JA, Garner P, Garnett J, Gribble S, Griffiths C, Grocock R, Gustafson E, Hammond S, Harley JL, Hart E, Heath PD, Ho TP, Hopkins B, Horne J, Howden PJ, Huckle E, Hynds C, Johnson C, Johnson D, Kana A, Kay M, Kimberley AM, Kershaw JK, Kokkinaki M, Laird GK, Lawlor S, Lee HM, Leongamornlert DA, Laird G, Lloyd C, Lloyd DM, Loveland J, Lovell J, McLaren S, McLay KE, McMurray A, Mashreghi-Mohammadi M, Matthews L, Milne S, Nickerson T, Nguyen M, Overton-Larty E, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter K, Rice CM, Rogosin A, Ross MT, Sarafidou T, Sehra HK, Shownkeen R, Skuce CD, Smith M, Standring L, Sycamore N, Tester J, Thorpe A, Torcasso W, Tracey A, Tromans A, Tsolas J, Wall M, Walsh J, Wang H, Weinstock K, West AP, Willey DL, Whitehead SL, Wilming L, Wray PW, Young L, Chen Y, Lovering RC, Moschonas NK, Siebert R, Fechtel K, Bentley D, Durbin R, Hubbard T, Doucette-Stamm L, Beck S, Smith DR, Rogers J
Nature. 2004
PubMed ID: 15164054
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Hao Z, Hampel B, Yagita H, Rajewsky K
J Exp Med. 2004
PubMed ID: 15148335
The roles of thymidylate synthase and p53 in regulating Fas-mediated apoptosis in response to antimetabolites.
Longley DB, Allen WL, McDermott U, Wilson TR, Latif T, Boyer J, Lynch M, Johnston PG
Clin Cancer Res. 2004
PubMed ID: 15161716
High-throughput association testing on DNA pools to identify genetic variants that confer susceptibility to acute myeloid leukemia.
Rollinson S, Allan JM, Law GR, Roddam PL, Smith MT, Skibola C, Smith AG, Forrest MS, Sibley K, Higuchi R, Germer S, Morgan GJ
Cancer Epidemiol Biomarkers Prev. 2004
PubMed ID: 15159312
Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption.
Minagawa M, Deng Q, Liu ZX, Tsukamoto H, Dennert G
Gastroenterology. 2004
PubMed ID: 15131799
Pro-Th1 cytokines promote Fas-dependent apoptosis of immature peripheral basophils.
Schneider E, Tonanny MB, Lisbonne M, Leite-de-Moraes M, Dy M
J Immunol. 2004
PubMed ID: 15100264
Mechanisms of tolerance induced by transforming growth factor-beta-treated antigen-presenting cells: CD8 regulatory T cells inhibit the effector phase of the immune response in primed mice through a mechanism involving Fas ligand.
Kosiewicz MM, Alard P, Liang S, Clark SL
Int Immunol. 2004
PubMed ID: 15096489
Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr.
Morito N, Yoh K, Hirayama A, Itoh K, Nose M, Koyama A, Yamamoto M, Takahashi S
Kidney Int. 2004
PubMed ID: 15086909
Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population.
Korstanje R, Li R, Howard T, Kelmenson P, Marshall J, Paigen B, Churchill G
J Lipid Res. 2004
PubMed ID: 14993241
CD95/phosphorylated ezrin association underlies HIV-1 GP120/IL-2-induced susceptibility to CD95(APO-1/Fas)-mediated apoptosis of human resting CD4(+)T lymphocytes.
Luciani F, Matarrese P, Giammarioli AM, Lugini L, Lozupone F, Federici C, Iessi E, Malorni W, Fais S
Cell Death Differ. 2004
PubMed ID: 14739941
c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas S, Lietz A, Anagnostopoulos I, Hummel F, Wiesner B, Janz M, Jundt F, Hirsch B, Jöhrens-Leder K, Vornlocher HP, Bommert K, Stein H, Dörken B
J Exp Med. 2004
PubMed ID: 15078899
Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells.
Ekland EH, Forster R, Lipp M, Cyster JG
J Immunol. 2004
PubMed ID: 15067045
Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction.
Heath RM, Jayne DG, O'Leary R, Morrison EE, Guillou PJ
Br J Cancer. 2004
PubMed ID: 15054468
Assessment of bcl-2 expression as modulator of fas mediated apoptosis in acute leukemia.
Aref S, Salama O, Al-Tonbary Y, Mansour A
Hematology. 2004
PubMed ID: 15203866
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Spatiotemporal analysis of programmed cell death during mouse cardiac septation.
Sharma PR, Anderson RH, Copp AJ, Henderson DJ
Anat Rec A Discov Mol Cell Evol Biol. 2004
PubMed ID: 15052663
Genomic analysis of Fas and FasL genes and absence of correlation with disease progression in AIDS.
Vasilescu A, Heath SC, Diop G, Do H, Hirtzig T, Hendel H, Bertin-Maghit S, Rappaport J, Therwath A, Lathrop GM, Matsuda F, Zagury JF
Immunogenetics. 2004
PubMed ID: 15042330
Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells.
Hiatt K, Ingram DA, Huddleston H, Spandau DF, Kapur R, Clapp DW
Am J Pathol. 2004
PubMed ID: 15039234
Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections.
Fuller MJ, Khanolkar A, Tebo AE, Zajac AJ
J Immunol. 2004
PubMed ID: 15034033
Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation.
Ma Y, Liu H, Tu-Rapp H, Thiesen HJ, Ibrahim SM, Cole SM, Pope RM
Nat Immunol. 2004
PubMed ID: 15004557
Fas signaling induces Akt activation and upregulation of endothelial nitric oxide synthase expression.
Takemura Y, Fukuo K, Yasuda O, Inoue T, Inomata N, Yokoi T, Kawamoto H, Suhara T, Ogihara T
Hypertension. 2004
PubMed ID: 14967838
Tip, an Lck-interacting protein of Herpesvirus saimiri, causes Fas- and Lck-dependent apoptosis of T lymphocytes.
Hasham MG, Tsygankov AY
Virology. 2004
PubMed ID: 15016553
CD95-tyrosine nitration inhibits hyperosmotic and CD95 ligand-induced CD95 activation in rat hepatocytes.
Reinehr R, Görg B, Höngen A, Häussinger D
J Biol Chem. 2004
PubMed ID: 14679192
Identification and relevance of the CD95-binding domain in the N-terminal region of ezrin.
Lozupone F, Lugini L, Matarrese P, Luciani F, Federici C, Iessi E, Margutti P, Stassi G, Malorni W, Fais S
J Biol Chem. 2004
PubMed ID: 14676203
Development of lymphoma in Autoimmune Lymphoproliferative Syndrome (ALPS) and its relationship to Fas gene mutations.
Poppema S, Maggio E, van den Berg A
Leuk Lymphoma. 2004
PubMed ID: 15160902
Incidence of Fas positivity and deoxyribonucleic acid double-stranded breaks in human ejaculated sperm.
McVicar CM, McClure N, Williamson K, Dalzell LH, Lewis SE
Fertil Steril. 2004
PubMed ID: 15019807
Association of FAS (TNFRSF6)-670 gene polymorphism with villous atrophy in coeliac disease.
Wu J, Alizadeh BZ, Veen TV, Meijer JW, Mulder CJ, Pena AS
World J Gastroenterol. 2004
PubMed ID: 14991945
Decreased phagocytosis of apoptotic cells in diseased SLE mice.
Licht R, Dieker JW, Jacobs CW, Tax WJ, Berden JH
J Autoimmun. 2004
PubMed ID: 14987742
The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression.
Kong PL, Morel L, Croker BP, Craft J
J Immunol. 2004
PubMed ID: 14978078
IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling.
Li C, Chi S, He N, Zhang X, Guicherit O, Wagner R, Tyring S, Xie J
Oncogene. 2004
PubMed ID: 14647422
Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Hayley S, Crocker SJ, Smith PD, Shree T, Jackson-Lewis V, Przedborski S, Mount M, Slack R, Anisman H, Park DS
J Neurosci. 2004
PubMed ID: 14985447
Altered expression of FAS system is related to adverse clinical outcome in stage I-II breast cancer patients treated with adjuvant anthracycline-based chemotherapy.
Botti C, Buglioni S, Benevolo M, Giannarelli D, Papaldo P, Cognetti F, Vici P, Di Filippo F, Del Nonno F, Venanzi FM, Natali PG, Mottolese M
Clin Cancer Res. 2004
PubMed ID: 14977837
Modulation of Th1 activation and inflammation by the NF-kappaB repressor Foxj1.
Lin L, Spoor MS, Gerth AJ, Brody SL, Peng SL
Science. 2004
PubMed ID: 14963332
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells.
Watabe M, Hishikawa K, Takayanagi A, Shimizu N, Nakaki T
J Biol Chem. 2004
PubMed ID: 14625298
Calmodulin binding to the Fas death domain. Regulation by Fas activation.
Ahn EY, Lim ST, Cook WJ, McDonald JM
J Biol Chem. 2004
PubMed ID: 14594800
Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death.
Muppidi JR, Siegel RM
Nat Immunol. 2004
PubMed ID: 14745445
Association of donor TNFRSF6 (FAS) gene polymorphism with acute rejection in renal transplant patients: a case-control study.
Cappellesso S, Valentin JF, Giraudeau B, Boulanger MD, Al-Najjar A, Büchler M, Halimi JM, Nivet H, Bardos P, Lebranchu Y, Watier H
Nephrol Dial Transplant. 2004
PubMed ID: 14736971
Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice.
Paul E, Lutz J, Erikson J, Carroll MC
Int Immunol. 2004
PubMed ID: 14734623
Differential activation of the Fas/CD95 pathway by Ad-p53 in human gliomas.
Cerrato JA, Khan T, Koul D, Lang FF, Conrad CA, Yung WK, Liu TJ
Int J Oncol. 2004
PubMed ID: 14719118
Arsenic trioxide-induced apoptosis is independent of CD95 in lymphatic cell lines.
Rojewski MT, Körper S, Thiel E, Schrezenmeier H
Oncol Rep. 2004
PubMed ID: 14719092
Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Roos W, Baumgartner M, Kaina B
Oncogene. 2004
PubMed ID: 14724564
TCR-independent and caspase-independent apoptosis of murine thymocytes by CD24 cross-linking.
Jung KC, Park WS, Kim HJ, Choi EY, Kook MC, Lee HW, Bae Y
J Immunol. 2004
PubMed ID: 14707049
Identification of an expanded binding surface on the FADD death domain responsible for interaction with CD95/Fas.
Hill JM, Morisawa G, Kim T, Huang T, Wei Y, Wei Y, Werner MH
J Biol Chem. 2004
PubMed ID: 14573612
Soluble Fas and soluble FasL in multiple organ dysfunction syndrome complicating diffuse peritonitis.
Kitamura M, Endo S, Sato N, Yaegashi Y, Suxzuki Y, Kojika N, Wakabayashi G
Res Commun Mol Pathol Pharmacol. 2004
PubMed ID: 17564320
Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.
Hoser G, Wasilewska D, Domagała-Kulawik J
Folia Histochem Cytobiol. 2004
PubMed ID: 15704653
Elevated caspase-3 and Fas mRNA expression in jejunum of adult rats during subclinical zinc deficiency.
Didier A, Windisch W, Pfaffl MW
J Trace Elem Med Biol. 2004
PubMed ID: 15487762
A study of promoter and intronic markers of ApoI/Fas gene and the interaction with Fas ligand in relapsing multiple sclerosis.
Lucas M, Zayas MD, De Costa AF, Solano F, Chadli A, Dinca L, Izquierdo G
Eur Neurol. 2004
PubMed ID: 15218339
Allelic loss analysis of lymphomas induced in Fas-heterozygous deficient mice.
Ogawa S, Hong DP, Mori N, Umesako S, Song CW, Okumoto M
J Vet Med Sci. 2004
PubMed ID: 14960823
An unappreciated role for RNA surveillance.
Hillman RT, Green RE, Brenner SE
Genome Biol. 2004
PubMed ID: 14759258
The Fas promoter polymorphism at position -670 is not associated with late-onset sporadic Alzheimer's disease.
Rosenmann H, Meiner Z, Kahana E, Aladjem Z, Friedman G, Ben-Yehuda A, Grenader T, Wertman E, Abramsky O
Dement Geriatr Cogn Disord. 2004
PubMed ID: 14739535
Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses.
Choi C, Benveniste EN
Brain Res Brain Res Rev. 2004
PubMed ID: 14739003
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95.
Reinehr R, Häussinger D
Gastroenterology. 2004
PubMed ID: 14699504
CD95 polymorphisms are associated with susceptibility to MS in women. A population-based study of CD95 and CD95L in MS.
Kantarci OH, Hebrink DD, Achenbach SJ, Atkinson EJ, de Andrade M, McMurray CT, Weinshenker BG
J Neuroimmunol. 2004
PubMed ID: 14698859
The death domain of kidney ankyrin interacts with Fas and promotes Fas-mediated cell death in renal epithelia.
Del Rio M, Imam A, DeLeon M, Gomez G, Mishra J, Ma Q, Parikh S, Devarajan P
J Am Soc Nephrol. 2004
PubMed ID: 14694156
Fas gene promoter polymorphisms in primary Sjögren's syndrome.
Mullighan CG, Heatley S, Lester S, Rischmueller M, Gordon TP, Bardy PG
Ann Rheum Dis. 2004
PubMed ID: 14672901
Enhancement of death-receptor induced caspase-8-activation in the death-inducing signalling complex by uncoupling of oxidative phosphorylation.
Vier J, Gerhard M, Wagner H, Häcker G
Mol Immunol. 2004
PubMed ID: 14644092
EGF mediates protection against Fas-induced apoptosis by depleting and oxidizing intracellular GSH stocks.
Musallam L, Ethier C, Haddad PS, Bilodeau M
J Cell Physiol. 2004
PubMed ID: 14584045
Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: implicating interleukin-2 for auto-reactive T cell expansion and Fas ligand for colon epithelial cell death.
Xiao S, Sung SS, Fu SM, Ju ST
J Biol Chem. 2003
PubMed ID: 14525977
Two distinct transport motifs in the adenovirus E3/10.4-14.5 proteins act in concert to down-modulate apoptosis receptors and the epidermal growth factor receptor.
Hilgendorf A, Lindberg J, Ruzsics Z, Höning S, Elsing A, Löfqvist M, Engelmann H, Burgert HG
J Biol Chem. 2003
PubMed ID: 14506242
Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: different roles of ERK and NF-kappaB signaling pathways.
Guo Z, Zhang M, An H, Chen W, Liu S, Guo J, Yu Y, Cao X
Blood. 2003
PubMed ID: 12920043
Long form of cellular FLICE-inhibitory protein interacts with Daxx and prevents Fas-induced JNK activation.
Kim YY, Park BJ, Seo GJ, Lim JY, Lee SM, Kimm KC, Park C, Kim J, Park SI
Biochem Biophys Res Commun. 2003
PubMed ID: 14637155
CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle J, Fecker LF, Hossini AM, Wieder T, Daniel PT, Orfanos CE, Geilen CC
Oncogene. 2003
PubMed ID: 14668794
Decreased levels of CD95 and caspase-8 mRNA in multiple sclerosis patients with gadolinium-enhancing lesions on MRI.
Gomes AC, Morris M, Stawiarz L, Jönsson G, Putheti P, Bronge L, Link H, Hillert J
Neurosci Lett. 2003
PubMed ID: 14625033
Abnormal structural luteolysis in ovaries of the senescence accelerated mouse (SAM): expression of Fas ligand/Fas-mediated apoptosis signaling molecules in luteal cells.
Kiso M, Manabe N, Komatsu K, Shimabe M, Miyamoto H
J Reprod Dev. 2003
PubMed ID: 14967896
Expression of Fas and Fas ligand protein and mRNA in mouse oocytes and embryos.
Kelkar RL, Dharma SJ, Nandedkar TD
Reproduction. 2003
PubMed ID: 14748698
In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells.
Bang B, Gniadecki R, Larsen JK, Baadsgaard O, Skov L
Exp Dermatol. 2003
PubMed ID: 14714559
Protection against murine leukemia virus-induced spongiform myeloencephalopathy in mice overexpressing Bcl-2 but not in mice deficient for interleukin-6, inducible nitric oxide synthetase, ICE, Fas, Fas ligand, or TNF-R1 genes.
Jolicoeur P, Hu C, Mak TW, Martinou JC, Kay DG
J Virol. 2003
PubMed ID: 14645573
Mechanisms of caspase activation.
Boatright KM, Salvesen GS
Curr Opin Cell Biol. 2003
PubMed ID: 14644197
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice.
Feldstein AE, Canbay A, Guicciardi ME, Higuchi H, Bronk SF, Gores GJ
J Hepatol. 2003
PubMed ID: 14642615
Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle.
Shinoda R, Watanabe M, Nakamura Y, Maruoka H, Kimura Y, Iwatani Y
J Reprod Immunol. 2003
PubMed ID: 14638442
Differential regulation of peripheral CD4+ T cell tolerance induced by deletion and TCR revision.
Ali M, Weinreich M, Balcaitis S, Cooper CJ, Fink PJ
J Immunol. 2003
PubMed ID: 14634147
Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans.
Marsik C, Halama T, Cardona F, Wlassits W, Mayr F, Pleiner J, Jilma B
Shock. 2003
PubMed ID: 14625471
Ontogenic changes in CD95 expression on human leukocytes: prevalence of T-cells expressing activation markers and identification of CD95-CD45RO+ T-cells in the fetus.
Muench MO, Pott Bärtsch EM, Chen JC, Lopoo JB, Bárcena A
Dev Comp Immunol. 2003
PubMed ID: 12880639
Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim.
Pellegrini M, Belz G, Bouillet P, Strasser A
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14623954
Analysis of Fas (Apo-1/CD95) expression in non-small cell lung cancer.
Esposito V, Baldi A, Liuzzi G, Tonini G, Vincenzi B, Persichetti P, Santini M, Ambrogi V, Mineo TC, Montesarchio V, Wolner E, Baldi F, Groeger AM
Anticancer Res. 2003
PubMed ID: 14981943
Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related.
Dunkern T, Roos W, Kaina B
Mutat Res. 2003
PubMed ID: 14644318
No association of two Fas gene polymorphisms with Hashimoto's thyroiditis and Graves' disease.
Stuck BJ, Pani MA, Besrour F, Segni M, Krause M, Usadel KH, Badenhoop K
Eur J Endocrinol. 2003
PubMed ID: 14585083
Combined deficiency in CD44 and Fas leads to exacerbation of lymphoproliferative and autoimmune disease.
Do Y, Rafi-Janajreh AQ, McKallip RJ, Nagarkatti PS, Nagarkatti M
Int Immunol. 2003
PubMed ID: 14565931
Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor.
Zanardi TA, Yei S, Lichtenstein DL, Tollefson AE, Wold WS
J Virol. 2003
PubMed ID: 14557654
Death receptor-dependent and -independent pathways in anticancer drug-induced apoptosis of breast cancer cells.
Kim R, Tanabe K, Emi M, Uchida Y, Toge T
Oncol Rep. 2003
PubMed ID: 14534720
Soluble Fas (CD95/Apo-1), soluble Fas ligand, and activated caspase 3 in the cerebrospinal fluid of infants with posthemorrhagic and nonhemorrhagic hydrocephalus.
Felderhoff-Mueser U, Buhrer C, Groneck P, Obladen M, Bartmann P, Heep A
Pediatr Res. 2003
PubMed ID: 12867600
Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis.
Zazzeroni F, Papa S, Algeciras-Schimnich A, Alvarez K, Melis T, Bubici C, Majewski N, Hay N, De Smaele E, Peter ME, Franzoso G
Blood. 2003
PubMed ID: 12855571
Mediation of enhanced transcription of the IL-10 gene in T cells, upon contact with human glioma cells, by Fas signaling through a protein kinase A-independent pathway.
Yang BC, Lin HK, Hor WS, Hwang JY, Lin YP, Liu MY, Wang YJ
J Immunol. 2003
PubMed ID: 14530312
Fas A670G polymorphism, apoptotic capacity in lymphocyte cultures, and risk of lung cancer.
Wang LE, Cheng L, Spitz MR, Wei Q
Lung Cancer. 2003
PubMed ID: 14512182
Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.
Wilber A, O'Connor TP, Lu ML, Karimi A, Schneider MC
Clin Exp Immunol. 2003
PubMed ID: 12974753
Ameliorating effect of anti-Fas ligand MAb on wasting disease in murine model of chronic colitis.
Dan N, Kanai T, Totsuka T, Iiyama R, Yamazaki M, Sawada T, Miyata T, Yagita H, Okumura K, Watanabe M
Am J Physiol Gastrointest Liver Physiol. 2003
PubMed ID: 12969829
Alterations in leucocyte trafficking in lupus-prone mice: an examination of the MRL/faslpr mouse.
Hickey MJ
Immunol Cell Biol. 2003
PubMed ID: 12969327
Oligomerization of soluble Fas antigen induces its cytotoxicity.
Proussakova OV, Rabaya NA, Moshnikova AB, Telegina ES, Turanov A, Nanazashvili MG, Beletsky IP
J Biol Chem. 2003
PubMed ID: 12855687
Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo.
Ugolini G, Raoul C, Ferri A, Haenggeli C, Yamamoto Y, Salaün D, Henderson CE, Kato AC, Pettmann B, Hueber AO
J Neurosci. 2003
PubMed ID: 13679421
Antiapoptotic function of NF-kappaB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL.
Mora AL, Corn RA, Stanic AK, Goenka S, Aronica M, Stanley S, Ballard DW, Joyce S, Boothby M
Cell Death Differ. 2003
PubMed ID: 12934078
Both the Fas ligand and inducible nitric oxide synthase are needed for control of parasite replication within lesions in mice infected with Leishmania major whereas the contribution of tumor necrosis factor is minimal.
Chakour R, Guler R, Bugnon M, Allenbach C, Garcia I, Mauël J, Louis J, Tacchini-Cottier F
Infect Immun. 2003
PubMed ID: 12933876
Two distinct mechanisms for induction of dendritic cell apoptosis in response to intact Streptococcus pneumoniae.
Colino J, Snapper CM
J Immunol. 2003
PubMed ID: 12928382
Increased plasma cell frequency and accumulation of abnormal syndecan-1plus T-cells in Igmu-deficient/lpr mice.
Seagal J, Leider N, Wildbaum G, Karin N, Melamed D
Int Immunol. 2003
PubMed ID: 12917256
Fas stimulation activates NF-kappaB in SK-Hep1 hepatocellular carcinoma cells.
Okano H, Shiraki K, Inoue H, Kawakita T, Saitou Y, Enokimura N, Yamamoto N, Sugimoto K, Murata K, Nakano T
Oncol Rep. 2003
PubMed ID: 12883671
Characterization of p53-mediated up-regulation of CD95 gene expression upon genotoxic treatment in human breast tumor cells.
Ruiz-Ruiz C, Robledo G, Cano E, Redondo JM, Lopez-Rivas A
J Biol Chem. 2003
PubMed ID: 12788915
Expression of Fas antigen and Fas ligand in bronchoalveolar lavage from silicosis patients.
Hamzaoui A, Ammar J, Graïri H, Hamzaoui K
Mediators Inflamm. 2003
PubMed ID: 14514471
Analysis of FAS (CD95) gene mutations in higher-grade transformation of follicle center lymphoma.
Do B, Lossos IS, Thorstenson Y, Oefner PJ, Levy R
Leuk Lymphoma. 2003
PubMed ID: 12952224
Distinct patterns of cleavage and translocation of cell cycle control proteins in CD95-induced and p53-induced apoptosis.
Park WS, Jung KC, Chung DH, Nam WD, Choi WJ, Bae Y
J Korean Med Sci. 2003
PubMed ID: 12923319
Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia.
Sibley K, Rollinson S, Allan JM, Smith AG, Law GR, Roddam PL, Skibola CF, Smith MT, Morgan GJ
Cancer Res. 2003
PubMed ID: 12907599
Constitutive caspase activation and impaired death-inducing signaling complex formation in CD95-resistant, long-term activated, antigen-specific T cells.
Strauss G, Knape I, Melzner I, Debatin KM
J Immunol. 2003
PubMed ID: 12874203
Soluble Fas (FasB) regulates luteal cell apoptosis during luteolysis in murine ovaries.
Komatsu K, Manabe N, Kiso M, Shimabe M, Miyamoto H
Mol Reprod Dev. 2003
PubMed ID: 12840807
Involvement of Fas and TNF pathways in the induction of apoptosis of T cells by antithymocyte globulin.
Dubey S, Nityanand S
Ann Hematol. 2003
PubMed ID: 12783210
Necrotic cell death in response to oxidant stress involves the activation of the apoptogenic caspase-8/bid pathway.
Wang X, Ryter SW, Dai C, Tang ZL, Watkins SC, Yin XM, Song R, Choi AM
J Biol Chem. 2003
PubMed ID: 12754217
Elucidation of molecular events leading to neutrophil apoptosis following phagocytosis: cross-talk between caspase 8, reactive oxygen species, and MAPK/ERK activation.
Zhang B, Hirahashi J, Cullere X, Mayadas TN
J Biol Chem. 2003
PubMed ID: 12736263
Fas is not essential for lamina propria T lymphocyte homeostasis.
Boone DL, Dassopoulos T, Chai S, Chien M, Lodolce J, Ma A
Am J Physiol Gastrointest Liver Physiol. 2003
PubMed ID: 12702495
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes.
Micheau O, Tschopp J
Cell. 2003
PubMed ID: 12887920
Role of Fas/Fas ligand-mediated apoptosis in murine contact hypersensitivity.
Xu B, Bulfone-Paus S, Aoyama K, Yu S, Huang P, Morimoto K, Matsushita T, Takeuchi T
Int Immunopharmacol. 2003
PubMed ID: 12810350
Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.
Dybedal I, Yang L, Bryder D, Aastrand-Grundstrom I, Leandersson K, Jacobsen SE
Blood. 2003
PubMed ID: 12637333
Vitamin C inhibits FAS-induced apoptosis in monocytes and U937 cells.
Perez-Cruz I, Carcamo JM, Golde DW
Blood. 2003
PubMed ID: 12623840
Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation.
Sharov AA, Weiner L, Sharova TY, Siebenhaar F, Atoyan R, Reginato AM, McNamara CA, Funa K, Gilchrest BA, Brissette JL, Botchkarev VA
EMBO J. 2003
PubMed ID: 12805214
Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages.
Park DR, Thomsen AR, Frevert CW, Pham U, Skerrett SJ, Kiener PA, Liles WC
J Immunol. 2003
PubMed ID: 12794152
Alterations in Fas expression are characteristic of, but not solely responsible for, enhanced metastatic competence.
Liu K, Abrams SI
J Immunol. 2003
PubMed ID: 12794124
The CD95 type I/type II model.
Barnhart BC, Alappat EC, Peter ME
Semin Immunol. 2003
PubMed ID: 14563117
Prognostic significance of Fas expression in retinoblastoma.
Shanmugam MP, Lakshmi A, Biswas J, Krishnakumar S
Ocul Immunol Inflamm. 2003
PubMed ID: 14533029
Androgen and the blocking of radiation-induced sensitization to Fas-mediated apoptosis through c-jun induction in prostate cancer cells.
Shimada K, Nakamura M, Ishida E, Kishi M, Konishi N
Int J Radiat Biol. 2003
PubMed ID: 12963547
Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice.
Freyschmidt-Paul P, McElwee KJ, Botchkarev V, Kissling S, Wenzel E, Sundberg JP, Happle R, Hoffmann R
J Investig Dermatol Symp Proc. 2003
PubMed ID: 12895005
Fas siRNA reduces apoptotic cell death of allogeneic-transplanted hepatocytes in mouse spleen.
Wang J, Li W, Min J, Ou Q, Chen J
Transplant Proc. 2003
PubMed ID: 12826229
Effect of genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production and renal disease in MRL/lpr mice.
Molano ID, Redmond S, Sekine H, Zhang XK, Reilly C, Hutchison F, Ruiz P, Gilkeson GS
Clin Immunol. 2003
PubMed ID: 12804532
A new mutation, ataxia and male sterility (ams), of autoimmune-prone MRL/lpr mouse is not linked to lpr gene but associated with reduction of spleen size and alteration of lymphocyte subpopulations.
Pineda LL, Nakano A, Iijima M, Wada M, Yamasaki Y, Harada T
Pathol Int. 2003
PubMed ID: 12787314
Ataxia and male sterility (AMS) mouse. A new genetic variant exhibiting degeneration and loss of cerebellar Purkinje cells and spermatic cells.
Harada T, Pineda LL, Nakano A, Omura K, Zhou L, Iijima M, Yamasaki Y, Yokoyama M
Pathol Int. 2003
PubMed ID: 12787313
Constitutive over-expression of the insulin receptor substrate-1 causes functional up-regulation of Fas receptor.
Wiedmann M, Tamaki S, Silberman R, de la Monte SM, Cousens L, Wands JR
J Hepatol. 2003
PubMed ID: 12763374
Involvement of death receptor Fas in germ cell degeneration in gonads of Kit-deficient Wv/Wv mutant mice.
Sakata S, Sakamaki K, Watanabe K, Nakamura N, Toyokuni S, Nishimune Y, Mori C, Yonehara S
Cell Death Differ. 2003
PubMed ID: 12761576
Fas expression on T cells and sFas in relapsing-remitting multiple sclerosis.
Bilinska M, Frydecka I, Podemski R, Gruszka E
Acta Neurol Scand. 2003
PubMed ID: 12757469
Autoimmune kidney disease and lymphadenopathy in NODlpr mice are not modified by deficiency in tumor necrosis factor receptor 1 or beta 2-microglobulin.
Catterall T, Stockwell D, Marshall V, Strasser A, Allison J
Int Immunol. 2003
PubMed ID: 12750352
Apoptosis in uterine epithelium and decidua in response to implantation: evidence for two different pathways.
Joswig A, Gabriel HD, Kibschull M, Winterhager E
Reprod Biol Endocrinol. 2003
PubMed ID: 12801416
Responding naive T cells differ in their sensitivity to Fas engagement: early death of many T cells is compensated by costimulation of surviving T cells.
Maksimow M, Santanen M, Jalkanen S, Hänninen A
Blood. 2003
PubMed ID: 12531803
Overexpression of the 'silencer of death domain', SODD/BAG-4, modulates both TNFR1- and CD95-dependent cell death pathways.
Eichholtz-Wirth H, Fritz E, Wolz L
Cancer Lett. 2003
PubMed ID: 12706861
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation.
Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C
Immunity. 2003
PubMed ID: 12753742
The development of clinical activity in relapsing-remitting MS is associated with a decrease of FasL mRNA and an increase of Fas mRNA in peripheral blood.
Lopatinskaya L, van Boxel-Dezaire AH, Barkhof F, Polman CH, Lucas CJ, Nagelkerken L
J Neuroimmunol. 2003
PubMed ID: 12742662
FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface.
Ivanov VN, Lopez Bergami P, Maulit G, Sato TA, Sassoon D, Ronai Z
Mol Cell Biol. 2003
PubMed ID: 12724420
Fas-Fas ligand (CD95-CD95L) and cytotoxic T lymphocyte antigen-4 engagement mediate T cell unresponsiveness in patients with paracoccidioidomycosis.
Campanelli AP, Martins GA, Souto JT, Pereira MS, Livonesi MC, Martinez R, Silva JS
J Infect Dis. 2003
PubMed ID: 12717632
Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.
Singh RR, Saxena V, Zang S, Li L, Finkelman FD, Witte DP, Jacob CO
J Immunol. 2003
PubMed ID: 12707364
Immunohistochemical study of the apoptotic mechanisms in the intestinal mucosa during children's coeliac disease.
Ehrmann J, Kolek A, Kod'ousek R, Zapletalová J, Lísová S, Murray PG, Drábek J, Kolár Z
Virchows Arch. 2003
PubMed ID: 12698366
Expression of Fas/Fas-ligand, Bcl-2 protein and apoptosis in extravillous trophoblast along invasion to the decidua in human term placenta.
Murakoshi H, Matsuo H, Laoag-Fernandez JB, Samoto T, Maruo T
Endocr J. 2003
PubMed ID: 12803240
Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death.
Su JH, Anderson AJ, Cribbs DH, Tu C, Tong L, Kesslack P, Cotman CW
Neurobiol Dis. 2003
PubMed ID: 12742739
Concentrations of soluble Fas in maternal serum and amniotic fluid during uncomplicated pregnancies.
Malamitsi-Puchner A, Sarandakou A, Papagianni V, Protonotariou E, Tziotis J, Botsis D
J Soc Gynecol Investig. 2003
PubMed ID: 12699879
FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease.
Yajima K, Nakamura A, Sugahara A, Takai T
Eur J Immunol. 2003
PubMed ID: 12672068
IL-12 deficiency in MRL-Fas(lpr) mice delays nephritis and intrarenal IFN-gamma expression, and diminishes systemic pathology.
Kikawada E, Lenda DM, Kelley VR
J Immunol. 2003
PubMed ID: 12646661
Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation.
Reinehr R, Schliess F, Häussinger D
FASEB J. 2003
PubMed ID: 12586732
Soluble Fas in malignant pleural effusion and its expression in lung cancer cells.
Mitani K, Nishioka Y, Yamabe K, Ogawa H, Miki T, Yanagawa H, Sone S
Cancer Sci. 2003
PubMed ID: 12824926
Involvement of IL-18 and soluble fas in patients with postoperative hepatic failure.
Nakae H, Zheng YJ, Wada H, Tajimi K, Endo S
Eur Surg Res. 2003
PubMed ID: 12679613
Concomitant early appearance of anti-ribonucleoprotein and anti-nucleosome antibodies in lupus prone mice.
Laderach D, Koutouzov S, Bach JF, Yamamoto AM
J Autoimmun. 2003
PubMed ID: 12657529
High susceptibility of human leukemic cells to Fas-induced apoptosis is restricted to G1 phase of the cell cycle and can be increased by interferon treatment.
Jedema I, Barge RM, Willemze R, Falkenburg JH
Leukemia. 2003
PubMed ID: 12646947
Fas-mediated neutrophil apoptosis and associated A1 protein expression during systemic inflammation are regulated independently of both tumor necrosis factor receptors.
Kotani J, Avallone NJ, Lin E, Goshima M, Gandhi K, Lowry SF, Calvano SE
Shock. 2003
PubMed ID: 12630518
Cross-talk between tumor cells and neutrophils through the Fas (APO-1, CD95)/FasL system: human glioma cells enhance cell viability and stimulate cytokine production in neutrophils.
Hor WS, Huang WL, Lin YS, Yang BC
J Leukoc Biol. 2003
PubMed ID: 12629150
Anti-CD95-induced lethality requires radioresistant Fcgamma RII+ cells. A novel mechanism for fulminant hepatic failure.
Jodo S, Kung JT, Xiao S, Chan DV, Kobayashi S, Tateno M, Lafyatis R, Ju ST
J Biol Chem. 2003
PubMed ID: 12477718
Dysfunction of the Fas apoptotic signaling pathway in persistent polyclonal B-cell lymphocytosis.
Roussel M, Roué G, Sola B, Mossafa H, Troussard X
Haematologica. 2003
PubMed ID: 12604424
Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice.
Braun D, Geraldes P, Demengeot J
J Autoimmun. 2003
PubMed ID: 12604309
Simultaneous acceleration of the cell cycle and suppression of apoptosis by splice variant delta-6 of the candidate tumour suppressor LUCA-15/RBM5.
Mourtada-Maarabouni M, Sutherland LC, Meredith JM, Williams GT
Genes Cells. 2003
PubMed ID: 12581154
Fc receptor-independent development of autoimmune glomerulonephritis in lupus-prone MRL/lpr mice.
Matsumoto K, Watanabe N, Akikusa B, Kurasawa K, Matsumura R, Saito Y, Iwamoto I, Saito T
Arthritis Rheum. 2003
PubMed ID: 12571859
Fas engagement induces neurite growth through ERK activation and p35 upregulation.
Desbarats J, Birge RB, Mimouni-Rongy M, Weinstein DE, Palerme JS, Newell MK
Nat Cell Biol. 2003
PubMed ID: 12545171
CD28/B7 regulation of anti-CD3-mediated immunosuppression in vivo.
Tang Q, Smith JA, Szot GL, Zhou P, Alegre ML, Henriksen KJ, Thompson CB, Bluestone JA
J Immunol. 2003
PubMed ID: 12538715
Single nucleotide polymorphism at Fas promoter is associated with cervical carcinogenesis.
Lai HC, Sytwu HK, Sun CA, Yu MH, Yu CP, Liu HS, Chang CC, Chu TY
Int J Cancer. 2003
PubMed ID: 12455036
Cell-mediated fas-based lysis of dendritic cells which are apparently resistant to anti-Fas antibody.
Yokota A, Oikawa A, Matsuda C, Shinohara N, Eshima K
Microbiol Immunol. 2003
PubMed ID: 12801066
Expression of a functional Fas death receptor by human foetal motoneurons.
Lautrette C, Giraud S, Vermot-Desroches C, Preud'homme JL, Jauberteau MO
Neuroscience. 2003
PubMed ID: 12770553
Maternal serum of women with pre-eclampsia reduces trophoblast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosis.
Neale D, Demasio K, Illuzi J, Chaiworapongsa T, Romero R, Mor G
J Matern Fetal Neonatal Med. 2003
PubMed ID: 12710855
Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway.
Müller U, Sobek V, Balkow S, Hölscher C, Müllbacher A, Museteanu C, Mossmann H, Simon MM
Eur J Immunol. 2003
PubMed ID: 12594834
Enhancement of T cell apoptosis correlates with increased serum levels of soluble Fas (CD95/Apo-1) in active lupus.
Silvestris F, Grinello D, Tucci M, Cafforio P, Dammacco F
Lupus. 2003
PubMed ID: 12587820
Fas and c-kit are involved in the control of hair follicle melanocyte apoptosis and migration in chemotherapy-induced hair loss.
Sharov AA, Li GZ, Palkina TN, Sharova TY, Gilchrest BA, Botchkarev VA
J Invest Dermatol. 2003
PubMed ID: 12535195
Further evidence for role of a promoter variant in the TNFRSF6 gene in Alzheimer disease.
Feuk L, Prince JA, Blennow K, Brookes AJ
Hum Mutat. 2003
PubMed ID: 12497631
A novel signaling mechanism for soluble CD95 ligand. Synergy with anti-CD95 monoclonal antibodies for apoptosis and NF-kappaB nuclear translocation.
Xiao S, Jodo S, Sung SS, Marshak-Rothstein A, Ju ST
J Biol Chem. 2002
PubMed ID: 12393889
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern.
Li Y, Li H, Ni D, Weigert M
J Exp Med. 2002
PubMed ID: 12486097
Oxidative stress induces the expression of Fas and Fas ligand and apoptosis in murine intestinal epithelial cells.
Denning TL, Takaishi H, Crowe SE, Boldogh I, Jevnikar A, Ernst PB
Free Radic Biol Med. 2002
PubMed ID: 12488132
Fas-mediated apoptosis is important in regulating cell replication and death in trisomy 8 hematopoietic cells but not in cells with other cytogenetic abnormalities.
Sloand EM, Kim S, Fuhrer M, Risitano AM, Nakamura R, Maciejewski JP, Barrett AJ, Young NS
Blood. 2002
PubMed ID: 12393649
Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis.
Hou ST, Xie X, Baggley A, Park DS, Chen G, Walker T
J Biol Chem. 2002
PubMed ID: 12351630
Fas activation induces renal tubular epithelial cell beta 8 integrin expression and function in the absence of apoptosis.
Jarad G, Wang B, Khan S, DeVore J, Miao H, Wu K, Nishimura SL, Wible BA, Konieczkowski M, Sedor JR, Schelling JR
J Biol Chem. 2002
PubMed ID: 12324452
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Fas-mediated apoptosis in human lens epithelial cells of cataracts associated with diabetic retinopathy.
Okamura N, Ito Y, Shibata MA, Ikeda T, Otsuki Y
Med Electron Microsc. 2002
PubMed ID: 12658358
Lack of deleterious somatic mutations in the CD95 gene of plasmablasts from systemic lupus erythematosus patients and autoantibody-producing cell lines.
Kurth J, Perniok A, Schmitz R, Iking-Konert C, Chiorazzi N, Thompson KM, Winkler T, Rajewsky K, Küppers R
Eur J Immunol. 2002
PubMed ID: 12516573
A role for the Fas/Fas ligand apoptotic pathway in regulating myeloid progenitor cell kinetics.
Alenzi FQ, Marley SB, Lewis JL, Chandrashekran A, Warrens AN, Goldman JM, Gordon MY
Exp Hematol. 2002
PubMed ID: 12482505
Frequent deletion of Fas gene sequences encoding death and transmembrane domains in nasal natural killer/T-cell lymphoma.
Shen L, Liang AC, Lu L, Au WY, Kwong YL, Liang RH, Srivastava G
Am J Pathol. 2002
PubMed ID: 12466128
Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division.
Lee GK, Park HJ, Macleod M, Chandler P, Munn DH, Mellor AL
Immunology. 2002
PubMed ID: 12460190
Bone marrow B cell apoptosis during in vivo influenza virus infection requires TNF-alpha and lymphotoxin-alpha.
Sedger LM, Hou S, Osvath SR, Glaccum MB, Peschon JJ, van Rooijen N, Hyland L
J Immunol. 2002
PubMed ID: 12444124
Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase.
Hetz CA, Hunn M, Rojas P, Torres V, Leyton L, Quest AF
J Cell Sci. 2002
PubMed ID: 12415011
Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction.
Spaggiari GM, Contini P, Dondero A, Carosio R, Puppo F, Indiveri F, Zocchi MR, Poggi A
Blood. 2002
PubMed ID: 12393468
Glutathione peroxidase-1 protects from CD95-induced apoptosis.
Gouaze V, Andrieu-Abadie N, Cuvillier O, Malagarie-Cazenave S, Frisach MF, Mirault ME, Levade T
J Biol Chem. 2002
PubMed ID: 12221075
Activation of the p38 MAPK and ERK1/2 pathways is required for Fas-induced IL-8 production in colonic epithelial cells.
O'Brien D, O'Connor T, Shanahan F, O'Connell J
Ann N Y Acad Sci. 2002
PubMed ID: 12485855
Analysis of Fas gene mutations on laser capture microdissected specimens from renal cell carcinoma.
Takayama H, Takakuwa T, Tsujimoto Y, Nonomura N, Okuyama A, Aozasa K
Jpn J Cancer Res. 2002
PubMed ID: 12460460
Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis.
Datta SR, Ranger AM, Lin MZ, Sturgill JF, Ma YC, Cowan CW, Dikkes P, Korsmeyer SJ, Greenberg ME
Dev Cell. 2002
PubMed ID: 12431371
Oxidized low density lipoprotein potentiation of Fas-induced apoptosis through lectin-like oxidized-low density lipoprotein receptor-1 in human umbilical vascular endothelial cells.
Imanishi T, Hano T, Sawamura T, Takarada S, Nishio I
Circ J. 2002
PubMed ID: 12419941
Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.
Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB
Am J Pathol. 2002
PubMed ID: 12414525
Hydrogen peroxide induces upregulation of Fas in human airway epithelial cells via the activation of PARP-p53 pathway.
Fujita T, Maruyama M, Araya J, Sassa K, Kawagishi Y, Hayashi R, Matsui S, Kashii T, Yamashita N, Sugiyama E, Kobayashi M
Am J Respir Cell Mol Biol. 2002
PubMed ID: 12397013
Effect of IL-12 on TNF-alpha-mediated osteoclast formation in bone marrow cells: apoptosis mediated by Fas/Fas ligand interaction.
Kitaura H, Nagata N, Fujimura Y, Hotokezaka H, Yoshida N, Nakayama K
J Immunol. 2002
PubMed ID: 12391181
Adenovirus RIDbeta subunit contains a tyrosine residue that is critical for RID-mediated receptor internalization and inhibition of Fas- and TRAIL-induced apoptosis.
Lichtenstein DL, Krajcsi P, Esteban DJ, Tollefson AE, Wold WS
J Virol. 2002
PubMed ID: 12388693
TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid.
Werner AB, de Vries E, Tait SW, Bontjer I, Borst J
J Biol Chem. 2002
PubMed ID: 12196516
Synergistic engagement of an ineffective endogenous anti-tumor immune response and induction of IFN-gamma and Fas-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2.
Wigginton JM, Lee JK, Wiltrout TA, Alvord WG, Hixon JA, Subleski J, Back TC, Wiltrout RH
J Immunol. 2002
PubMed ID: 12370382
High levels of sFas and PBMC apoptosis before and after excision of malignant melanoma--case report.
Alecu M, Coman G, Dănăilă L
Roum Arch Microbiol Immunol. 2002
PubMed ID: 15055260
Bax, Bcl-2, fas and Fas-L antigen expression in human seminoma: correlation with the apoptotic index.
Grobholz R, Zentgraf H, Köhrmann KU, Bleyl U
APMIS. 2002
PubMed ID: 12583439
Prognostic significance of a combination of soluble Fas and soluble Fas ligand in the serum of patients with Ta bladder cancer.
Mizutani Y, Yoshida O, Ukimura O, Kawauchi A, Bonavida B, Miki T
Cancer Biother Radiopharm. 2002
PubMed ID: 12470426
Enhanced complement sensitivity of NK-T cells in murine thymus and spleen associated with presence of serum immunoglobulin.
Onoé K, Iwabuchi K, Iwabuchi C, Tone S, Konishi J, Kawakami Y, Nishimura M, Onoé K
Immunobiology. 2002
PubMed ID: 12437069
Cytokine-dependent bystander hepatitis due to intrahepatic murine CD8 T-cell activation by bone marrow-derived cells.
Bowen DG, Warren A, Davis T, Hoffmann MW, McCaughan GW, Fazekas de St Groth B, Bertolino P
Gastroenterology. 2002
PubMed ID: 12360486
Lymphoadenopathy in IL-2-deficient mice: further characterization and overexpression of the antiapoptotic molecule cellular FLIP.
Chastagner P, Reddy J, Thèze J
J Immunol. 2002
PubMed ID: 12244156
Fas resistance of leukemic eosinophils is due to activation of NF-kappa B by Fas ligation.
Qin Y, Camoretti-Mercado B, Blokh L, Long CG, Ko FD, Hamann KJ
J Immunol. 2002
PubMed ID: 12244143
Bcl-2-mediated regulation of CD69-induced apoptosis of human eosinophils: identification and characterization of a novel receptor-induced mechanism and relationship to CD95-transduced signalling.
Foerster M, Haefner D, Kroegel C
Scand J Immunol. 2002
PubMed ID: 12234263
Evaluation of a Apo-1/Fas promoter polymorphism in Korean stroke patients.
Seo JC, Han SW, Yin CS, Koh HK, Kim CH, Kim EH, Leem KH, Lee HS, Park HJ, Kim SA, Choe BK, Lee HJ, Yim SV, Kim CJ, Chung JH
Exp Mol Med. 2002
PubMed ID: 12515395
A new locus for resistance to gamma-radiation-induced thymic lymphoma identified using inter-specific consomic and inter-specific recombinant congenic strains of mice.
Santos J, Montagutelli X, Acevedo A, López P, Vaquero C, Fernández M, Arnau MR, Szatanik M, Salido E, Guénet JL, Fernández-Piqueras J
Oncogene. 2002
PubMed ID: 12242666
Evolution of autoantibody responses via somatic hypermutation outside of germinal centers.
William J, Euler C, Christensen S, Shlomchik MJ
Science. 2002
PubMed ID: 12242446
Regulation of Fas-associated death domain interactions by the death effector domain identified by a modified reverse two-hybrid screen.
Thomas LR, Stillman DJ, Thorburn A
J Biol Chem. 2002
PubMed ID: 12107169
Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.
Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B
Neuron. 2002
PubMed ID: 12354397
The conformational alteration of the mutated extracellular domain of Fas in an adult T cell leukemia cell line.
Maeda T, Nakayama S, Yamada Y, Sugahara K, Isomoto H, Tawara M, Yamasaki R, Onimaru Y, Matsushita T, Ohzono Y, Kamihira S
Biochem Biophys Res Commun. 2002
PubMed ID: 12207908
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.
Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H
EMBO J. 2002
PubMed ID: 12198154
Immunohistochemical expression of p53, Bcl-2, Bax, and Fas proteins in squamous cell carcinomas from immunosuppressed renal transplant recipients and immunocompetent individuals.
Seçkin D, Demirhan B, Karakayali H, Akgün S, Erdal R, Turan M
Transplant Proc. 2002
PubMed ID: 12270344
Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice.
Miwa T, Maldonado MA, Zhou L, Sun X, Luo HY, Cai D, Werth VP, Madaio MP, Eisenberg RA, Song WC
Am J Pathol. 2002
PubMed ID: 12213736
Antigen-induced cell death of T effector cells in vitro proceeds via the Fas pathway, requires endogenous interferon-gamma and is independent of perforin and granzymes.
Sobek V, Balkow S, Körner H, Simon MM
Eur J Immunol. 2002
PubMed ID: 12207333
Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.
Scheller C, Sopper S, Ehrhardt C, Flory E, Chen P, Koutsilieri E, Ludwig S, ter Meulen V, Jassoy C
Eur J Immunol. 2002
PubMed ID: 12207331
Role of CD44 in activation-induced cell death: CD44-deficient mice exhibit enhanced T cell response to conventional and superantigens.
McKallip RJ, Do Y, Fisher MT, Robertson JL, Nagarkatti PS, Nagarkatti M
Int Immunol. 2002
PubMed ID: 12202399
Extensive and preferential Fas/Fas ligand-dependent death of gammadelta T cells following infection with Listeria monocytogenes.
Mukasa A, Lahn M, Fleming S, Freiberg B, Pflum E, Vollmer M, Kupfer A, O'Brien R, Born W
Scand J Immunol. 2002
PubMed ID: 12193224
Hepatitis C virus core protein leads to immune suppression and liver damage in a transgenic murine model.
Soguero C, Joo M, Chianese-Bullock KA, Nguyen DT, Tung K, Hahn YS
J Virol. 2002
PubMed ID: 12186917
DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way.
Kulms D, Zeise E, Pöppelmann B, Schwarz T
Oncogene. 2002
PubMed ID: 12185583
An examination of the Apo-1/Fas promoter Mva I polymorphism in Japanese patients with multiple sclerosis.
Niino M, Kikuchi S, Fukazawa T, Miyagishi R, Yabe I, Tashiro K
BMC Neurol. 2002
PubMed ID: 12188927
A functional gene discovery in the Fas-mediated pathway to apoptosis by analysis of transiently expressed randomized hybrid-ribozyme libraries.
Kawasaki H, Taira K
Nucleic Acids Res. 2002
PubMed ID: 12177303
IL-10 regulates murine lupus.
Yin Z, Bahtiyar G, Zhang N, Liu L, Zhu P, Robert ME, McNiff J, Madaio MP, Craft J
J Immunol. 2002
PubMed ID: 12165544
Possible involvement of Fas system in the induction of apoptosis in human astrocytic brain tumors.
Fujita H, Koji T, Kitagawa N, Tsutsumi K, Abe K, Kaminogo M, Shibata S
Cell Mol Neurobiol. 2002
PubMed ID: 12507389
Death receptor Fas and autoimmune disease: from the original generation to therapeutic application of agonistic anti-Fas monoclonal antibody.
Yonehara S
Cytokine Growth Factor Rev. 2002
PubMed ID: 12220552
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy.
Maecker HL, Yun Z, Maecker HT, Giaccia AJ
Cancer Cell. 2002
PubMed ID: 12204534
Frequent Fas gene mutations in testicular germ cell tumors.
Takayama H, Takakuwa T, Tsujimoto Y, Tani Y, Nonomura N, Okuyama A, Nagata S, Aozasa K
Am J Pathol. 2002
PubMed ID: 12163388
Significant role of Fas ligand-binding but defective Fas receptor (CD95) in lymph node hyperplasia composed of abnormal double-negative T cells.
Matsuzawa A, Shimizu M, Takeda Y, Nagase H, Sayama K, Kimura M
Immunology. 2002
PubMed ID: 12153509
B and T cell tolerance and autoimmunity in autoantibody transgenic mice.
Yan J, Mamula MJ
Int Immunol. 2002
PubMed ID: 12147633
A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus.
Wu X, Jiang N, Deppong C, Singh J, Dolecki G, Mao D, Morel L, Molina HD
J Immunol. 2002
PubMed ID: 12133988
Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha.
Saile B, Matthes N, Neubauer K, Eisenbach C, El-Armouche H, Dudas J, Ramadori G
Am J Physiol Gastrointest Liver Physiol. 2002
PubMed ID: 12121892
Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells.
Lim SY, Lee SC, Shin I, Han JS
Exp Mol Med. 2002
PubMed ID: 12216112
CCR5 mediates Fas- and caspase-8 dependent apoptosis of both uninfected and HIV infected primary human CD4 T cells.
Algeciras-Schimnich A, Vlahakis SR, Villasis-Keever A, Gomez T, Heppelmann CJ, Bou G, Paya CV
AIDS. 2002
PubMed ID: 12131184
The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo.
Ford MS, Young KJ, Zhang Z, Ohashi PS, Zhang L
J Exp Med. 2002
PubMed ID: 12119351
Autocrine production of IFN-gamma by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice.
Carvalho-Pinto CE, García MI, Mellado M, Rodríguez-Frade JM, Martín-Caballero J, Flores J, Martínez-A C, Balomenos D
J Immunol. 2002
PubMed ID: 12097414
Thymidine phosphorylase suppresses Fas-induced apoptotic signal transduction independent of its enzymatic activity.
Mori S, Takao S, Ikeda R, Noma H, Mataki Y, Wang X, Akiyama S, Aikou T
Biochem Biophys Res Commun. 2002
PubMed ID: 12150947
Frequent mutations of Fas gene in nasal NK/T cell lymphoma.
Takakuwa T, Dong Z, Nakatsuka S, Kojya S, Harabuchi Y, Yang WI, Nagata S, Aozasa K
Oncogene. 2002
PubMed ID: 12096347
Constitutive expression of the Fas receptor and its ligand in adult human bone marrow: a regulatory feedback loop for the homeostatic control of hematopoiesis.
Brazil JJ, Gupta P
Blood Cells Mol Dis. 2002
PubMed ID: 12482410
Inhibition of MEK induces fas expression and apoptosis in lymphomas overexpressing Ras.
Kalas W, Kisielow P, Strzadala L
Leuk Lymphoma. 2002
PubMed ID: 12389631
Role of Fas/Fas ligand interaction in ischemia-induced collateral vessel growth.
Sata M, Hirata Y, Nagai R
Hypertens Res. 2002
PubMed ID: 12358144
Aberrant T-cell antigen receptor-mediated responses in autoimmune lymphoproliferative syndrome.
Goldman FD, Vibhakar R, Puck JM, Straus SE, Ballas ZK, Hollenback C, Loew T, Thompson A, Song K, Cook RT
Clin Immunol. 2002
PubMed ID: 12139945
The FAS-670 polymorphism influences susceptibility to multiple sclerosis.
van Veen T, Kalkers NF, Crusius JB, van Winsen L, Barkhof F, Jongen PJ, Peña AS, Polman CH, Uitdehaag BM
J Neuroimmunol. 2002
PubMed ID: 12098516
Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic mice.
Watanabe N, Ikuta K, Nisitani S, Chiba T, Honjo T
J Exp Med. 2002
PubMed ID: 12093879
Gammadelta T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand.
Huber S, Shi C, Budd RC
J Virol. 2002
PubMed ID: 12050361
Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer.
Shin MS, Kim HS, Lee SH, Lee JW, Song YH, Kim YS, Park WS, Kim SY, Lee SN, Park JY, Lee JH, Xiao W, Jo KH, Wang YP, Lee KY, Park YG, Kim SH, Lee JY, Yoo NJ
Oncogene. 2002
PubMed ID: 12037669
Frequent downregulation of Fas (CD95) expression and function in melanoma.
Bullani RR, Wehrli P, Viard-Leveugle I, Rimoldi D, Cerottini JC, Saurat JH, Tschopp J, French LE
Melanoma Res. 2002
PubMed ID: 12140383
[The role of Fas/Fas ligand in tumorgenesis, immune escape, and counterattack in colonic cancer]
Zhu Q, Deng C
Zhonghua Nei Ke Za Zhi. 2002
PubMed ID: 12137598
A functional polymorphism in fas (CD95/APO-1) gene promoter associated with systemic lupus erythematosus.
Kanemitsu S, Ihara K, Saifddin A, Otsuka T, Takeuchi T, Nagayama J, Kuwano M, Hara T
J Rheumatol. 2002
PubMed ID: 12064832
Infrequent Fas mutations but no Bax or p53 mutations in early mycosis fungoides: a possible mechanism for the accumulation of malignant T lymphocytes in the skin.
Dereure O, Levi E, Vonderheid EC, Kadin ME
J Invest Dermatol. 2002
PubMed ID: 12060388
Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1).
Kulms D, Düssmann H, Pöppelmann B, Ständer S, Schwarz A, Schwarz T
Cell Death Differ. 2002
PubMed ID: 12032668
Differential regulation and function of the Fas/Fas ligand system in human trophoblast cells.
Aschkenazi S, Straszewski S, Verwer KM, Foellmer H, Rutherford T, Mor G
Biol Reprod. 2002
PubMed ID: 12021072
The Fas signaling pathway: more than a paradigm.
Wajant H
Science. 2002
PubMed ID: 12040174
HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter.
Yang Y, Dong B, Mittelstadt PR, Xiao H, Ashwell JD
J Biol Chem. 2002
PubMed ID: 11909874
Fas-dependent elimination of nonselected CD8 cells and lpr disease.
Trimble LA, Prince KA, Pestano GA, Daley J, Cantor H
J Immunol. 2002
PubMed ID: 11994447
Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice.
Bolland S, Yim YS, Tus K, Wakeland EK, Ravetch JV
J Exp Med. 2002
PubMed ID: 11994421
[Fas and Fas-L expression in human adenocarcinoma of uterine cervix]
Chen B, Shi Y, Ge Y, Zhou C, Chen X
Zhonghua Zhong Liu Za Zhi. 2002
PubMed ID: 12515623
[Expression of Fas in six human urogenital malignant cell lines]
Li HJ, Yu LZ, Guo YL, Ding Y
Ai Zheng. 2002
PubMed ID: 12452031
Serum elevations of soluble Fas (CD95/apo-I) concur in deregulating T cell apoptosis during active lupus disease.
Silvestris F, Williams RC, Calvani N, Grinello D, Tucci M, Cafforio P, Dammacco F
Clin Exp Med. 2002
PubMed ID: 12049185
Recipient TNFRSF6 (FAS) gene polymorphism and acute renal allograft rejection.
Cappellesso S, Valentin JF, Al-Najjar A, Büchler M, Ngourn M, Halimi JM, Nivet H, Bardos P, Lebranchu Y, Watier H
Transplant Proc. 2002
PubMed ID: 12034188
Pathogenesis of Sjögren's syndrome: characteristics of different mouse models for autoimmune exocrinopathy.
van Blokland SC, Versnel MA
Clin Immunol. 2002
PubMed ID: 12027416
Hormonal regulation of apoptosis and the Fas and Fas ligand system in human endometrial cells.
Song J, Rutherford T, Naftolin F, Brown S, Mor G
Mol Hum Reprod. 2002
PubMed ID: 11994542
Activated T lymphocytes disappear from circulation during endotoxemia in humans.
Krabbe KS, Bruunsgaard H, Qvist J, Fonsmark L, Møller K, Hansen CM, Skinhøj P, Pedersen BK
Clin Diagn Lab Immunol. 2002
PubMed ID: 11986289
HLA class II signals sensitize B lymphocytes to apoptosis via Fas/CD95 by increasing FADD recruitment to activated Fas and activation of caspases.
Blancheteau V, Charron D, Mooney N
Hum Immunol. 2002
PubMed ID: 11975981
Leukocyte-endothelial cell interactions are enhanced in dermal postcapillary venules of MRL/fas(lpr) (lupus-prone) mice: roles of P- and E-selectin.
Hickey MJ, Bullard DC, Issekutz A, James WG
J Immunol. 2002
PubMed ID: 11971023
Mature dendritic cells are protected from Fas/CD95-mediated apoptosis by upregulation of Bcl-X(L).
Lundqvist A, Nagata T, Kiessling R, Pisa P
Cancer Immunol Immunother. 2002
PubMed ID: 11941452
Interferon-gamma increases the expression of glycosylated CD95 in B-leukemic cells: an inducible model to study the role of glycosylation in CD95-signalling and trafficking.
Dörrie J, Sapala K, Zunino SJ
Cytokine. 2002
PubMed ID: 12096925
c-myc-induced apoptosis in polycystic kidney disease is independent of FasL/Fas interaction.
Couillard M, Guillaume R, Tanji N, D'Agati V, Trudel M
Cancer Res. 2002
PubMed ID: 11956070
Role of p38 mitogen-activated protein kinase phosphorylation and Fas-Fas ligand interaction in morphine-induced macrophage apoptosis.
Singhal PC, Bhaskaran M, Patel J, Patel K, Kasinath BS, Duraisamy S, Franki N, Reddy K, Kapasi AA
J Immunol. 2002
PubMed ID: 11937560
CD95 engagement induces disseminated endothelial cell apoptosis in vivo: immunopathologic implications.
Janin A, Deschaumes C, Daneshpouy M, Estaquier J, Micic-Polianski J, Rajagopalan-Levasseur P, Akarid K, Mounier N, Gluckman E, Socié G, Ameisen JC
Blood. 2002
PubMed ID: 11929785
Apoptosis and related proteins during parturition in prostaglandin F receptor-deficient mice.
Mu J, Kanzaki T, Si X, Tomimatsu T, Fukuda H, Fujii E, Hosono T, Murata Y, Sugimoto Y, Ichikawa A
Biochem Biophys Res Commun. 2002
PubMed ID: 11922619
Apoptosis in the immune system: 1. Fas-induced apoptosis in monocytes-derived human dendritic cells.
Nat R, Radu E, Regalia T, Popescu LM
J Cell Mol Med. 2002
PubMed ID: 12169207
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells.
Seo SJ, Fields ML, Buckler JL, Reed AJ, Mandik-Nayak L, Nish SA, Noelle RJ, Turka LA, Finkelman FD, Caton AJ, Erikson J
Immunity. 2002
PubMed ID: 11970877
Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: studies on centenarians.
Pinti M, Troiano L, Nasi M, Moretti L, Monterastelli E, Mazzacani A, Mussi C, Ventura P, Olivieri F, Franceschi C, Salvioli G, Cossarizza A
Cell Death Differ. 2002
PubMed ID: 11965496
Differential expressions of Fas and Fas ligand in human placenta.
Roh CR, Lee JW, Kang BH, Yang SH, Kim BG, Bae DS, Kim JH, Lee JH
J Korean Med Sci. 2002
PubMed ID: 11961305
Apoptosis and expression of apoptosis-related genes in the mouse testis following heat exposure.
Miura M, Sasagawa I, Suzuki Y, Nakada T, Fujii J
Fertil Steril. 2002
PubMed ID: 11937135
Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.
Bao L, Haas M, Boackle SA, Kraus DM, Cunningham PN, Park P, Alexander JJ, Anderson RK, Culhane K, Holers VM, Quigg RJ
J Immunol. 2002
PubMed ID: 11907125
Lack of both Fas ligand and perforin protects from flavivirus-mediated encephalitis in mice.
Licon Luna RM, Lee E, Müllbacher A, Blanden RV, Langman R, Lobigs M
J Virol. 2002
PubMed ID: 11884544
Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.
Lorenzo E, Ruiz-Ruiz C, Quesada AJ, Hernández G, Rodríguez A, López-Rivas A, Redondo JM
J Biol Chem. 2002
PubMed ID: 11779855
Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition.
Tafani M, Karpinich NO, Hurster KA, Pastorino JG, Schneider T, Russo MA, Farber JL
J Biol Chem. 2002
PubMed ID: 11790791
Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia.
Chu P, Deforce D, Pedersen IM, Kim Y, Kitada S, Reed JC, Kipps TJ
Proc Natl Acad Sci U S A. 2002
PubMed ID: 11891278
Perforin- and Fas-dependent mechanisms of natural killer cell-mediated rejection of incompatible bone marrow cell grafts.
Taylor MA, Ward B, Schatzle JD, Bennett M
Eur J Immunol. 2002
PubMed ID: 11870623
Overexpression of the mouse Fas gene in human Hep3B hepatoma cells overcomes their resistance to Fas-mediated apoptosis.
Lamboley C, Bringuier AF, Camus E, Lardeux B, Groyer A, Feldmann G
J Hepatol. 2002
PubMed ID: 11867183
In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis.
Claessens YE, Bouscary D, Dupont JM, Picard F, Melle J, Gisselbrecht S, Lacombe C, Dreyfus F, Mayeux P, Fontenay-Roupie M
Blood. 2002
PubMed ID: 11861273
Participation of Fas-mediated apoptotic pathway in KB, a human head and neck squamous cell carcinoma cell line, after irradiation.
Uno M, Otsuki T, Yata K, Fujii T, Sakaguchi H, Akisada T, Hiratsuka J, Imajo Y, Harada T
Int J Oncol. 2002
PubMed ID: 11836578
Germline FAS gene mutation in a case of ALPS and NLP Hodgkin lymphoma.
van den Berg A, Maggio E, Diepstra A, de Jong D, van Krieken J, Poppema S
Blood. 2002
PubMed ID: 11830507
Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.
Ivanov VN, Krasilnikov M, Ronai Z
J Biol Chem. 2002
PubMed ID: 11733515
[Expression and function of CD95/fas antigen and Bcl-2 on cord blood hematopoietic progenitor cells]
Ma YP, Zhou P, Xiao J
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2002
PubMed ID: 12513829
Induction of apoptosis mediated by fas receptor and activation of caspase-3 in MRL-+/+ or MRL-lpr/lpr murine oocytes.
Guo M, Sato E, Li X, Mori E, Saito S, Mori T
Zygote. 2002
PubMed ID: 11964087
A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.
Wang X, DeFrances MC, Dai Y, Pediaditakis P, Johnson C, Bell A, Michalopoulos GK, Zarnegar R
Mol Cell. 2002
PubMed ID: 11864613
Expression of CD95 (Fas) in sun-exposed human skin and cutaneous carcinomas.
Filipowicz E, Adegboyega P, Sanchez RL, Gatalica Z
Cancer. 2002
PubMed ID: 11857317
Elevated plus maze behavior, auditory startle response, and shock sensitivity in predisease and in early stage autoimmune disease MRL/lpr mice.
Nielsen DM, Crnic LS
Brain Behav Immun. 2002
PubMed ID: 11846440
Fas (CD95/Apo-1)/Fas ligand expression in neonates with pontosubicular neuron necrosis.
van Landeghem FK, Felderhoff-Mueser U, Moysich A, Stadelmann C, Obladen M, Brück W, Bührer C
Pediatr Res. 2002
PubMed ID: 11809905
Complement C4 is protective for lupus disease independent of C3.
Einav S, Pozdnyakova OO, Ma M, Carroll MC
J Immunol. 2002
PubMed ID: 11801636
Expression of Fas and Fas ligand in esophageal tissue mucosa and carcinomas.
Kase S, Osaki M, Adachi H, Kaibara N, Ito H
Int J Oncol. 2002
PubMed ID: 11788891
Fas engagement increases expression of interleukin-6 in human glioma cells.
Choi C, Gillespie GY, Van Wagoner NJ, Benveniste EN
J Neurooncol. 2002
PubMed ID: 11949822
Fas (Apo-1/CD95) and Fas ligand interaction between gastric cancer cells and immune cells.
Lee TB, Min YD, Lim SC, Kim KJ, Jeon HJ, Choi SM, Choi CH
J Gastroenterol Hepatol. 2002
PubMed ID: 11895550
Lack of association between juvenile idiopathic arthritis and fas gene polymorphism.
Donn R, Zeggini E, Shelley E, Ollier W, Thomson W, British Paediatric Rheumatology Study Group
J Rheumatol. 2002
PubMed ID: 11824955
Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils.
Daigle I, Yousefi S, Colonna M, Green DR, Simon HU
Nat Med. 2002
PubMed ID: 11786908
Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells.
Chopin V, Toillon RA, Jouy N, Le Bourhis X
Br J Pharmacol. 2002
PubMed ID: 11786482
Requirement of Fas expression in B cells for tolerance induction.
Fukuyama H, Adachi M, Suematsu S, Miwa K, Suda T, Yoshida N, Nagata S
Eur J Immunol. 2002
PubMed ID: 11782013
Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver.
Rüdiger HA, Clavien PA
Gastroenterology. 2002
PubMed ID: 11781294
P53 and Fas are sequential mechanisms of testicular germ cell apoptosis.
Yin Y, Stahl BC, DeWolf WC, Morgentaler A
J Androl. 2002
PubMed ID: 11780924
Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection.
Zhou S, Ou R, Huang L, Moskophidis D
J Virol. 2002
PubMed ID: 11752172
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway.
Faouzi S, Burckhardt BE, Hanson JC, Campe CB, Schrum LW, Rippe RA, Maher JJ
J Biol Chem. 2001
PubMed ID: 11602613
Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor.
Wenzel J, Sanzenbacher R, Ghadimi M, Lewitzky M, Zhou Q, Kaplan DR, Kabelitz D, Feller SM, Janssen O
FEBS Lett. 2001
PubMed ID: 11741599
Differential roles of osteopontin/Eta-1 in early and late lpr disease.
Weber GF, Cantor H
Clin Exp Immunol. 2001
PubMed ID: 11737079
Expression and regulation of Fas and Fas ligand on thyrocytes and infiltrating cells during induction and resolution of granulomatous experimental autoimmune thyroiditis.
Wei Y, Chen K, Sharp GC, Yagita H, Braley-Mullen H
J Immunol. 2001
PubMed ID: 11714840
Liver damage by infiltrating CD8+ T cells is Fas dependent.
Kennedy NJ, Russell JQ, Michail N, Budd RC
J Immunol. 2001
PubMed ID: 11714837
Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis.
Reddy P, Teshima T, Kukuruga M, Ordemann R, Liu C, Lowler K, Ferrara JL
J Exp Med. 2001
PubMed ID: 11714750
Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.
Adachi K, Tsutsui H, Kashiwamura S, Seki E, Nakano H, Takeuchi O, Takeda K, Okumura K, Van Kaer L, Okamura H, Akira S, Nakanishi K
J Immunol. 2001
PubMed ID: 11698470
A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease.
Esfandiari E, McInnes IB, Lindop G, Huang FP, Field M, Komai-Koma M, Wei X, Liew FY
J Immunol. 2001
PubMed ID: 11673550
Apoptosis-linked gene 2 binds to the death domain of Fas and dissociates from Fas during Fas-mediated apoptosis in Jurkat cells.
Jung YS, Kim KS, Kim KD, Lim JS, Kim JW, Kim E
Biochem Biophys Res Commun. 2001
PubMed ID: 11606059
Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm.
Ko YG, Kang YS, Park H, Seol W, Kim J, Kim T, Park HS, Choi EJ, Kim S
J Biol Chem. 2001
PubMed ID: 11495919
Apoptosis in human embryo development: 3. Fas-induced apoptosis in brain primary cultures.
Nat R, Radu E, Regalia T, Popescu LM
J Cell Mol Med. 2001
PubMed ID: 12067476
Soluble Fas antigen (sFAS) in the serum from patients with adrenal tumors.
Kushlinskii NE, Britvin TA, Polyakova GA, Abbasova SG, Baronin AA, Bogatyrev OP, Kalinin AP, Lipkin VM
Bull Exp Biol Med. 2001
PubMed ID: 11782802
Gamma-interferon induces apoptosis of the B lymphoma WEHI-279 cell line through a CD95/CD95L-independent mechanism.
Ben Jilani KE, Akarid K, Arnoult D, Petit F, Baert E, Gaillard JP, Ameisen JC, Estaquier J
Eur Cytokine Netw. 2001
PubMed ID: 11781185
Loss of CD95 expression is linked to most but not all p53 mutants in European hepatocellular carcinoma.
Volkmann M, Schiff JH, Hajjar Y, Otto G, Stilgenbauer F, Fiehn W, Galle PR, Hofmann WJ
J Mol Med. 2001
PubMed ID: 11692157
Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge.
Duez C, Tomkinson A, Shultz LD, Bratton DL, Gelfand EW
J Allergy Clin Immunol. 2001
PubMed ID: 11590380
Cytokines in autoimmune lacrimal gland disease in MRL/MpJ mice.
Jabs DA, Prendergast RA, Rorer EM, Hudson AP, Whittum-Hudson JA
Invest Ophthalmol Vis Sci. 2001
PubMed ID: 11581200
Effect of Fas and Fas ligand deficiency in resistance of C57BL/6 mice to HSV-1 keratitis and chorioretinitis.
Nguyen QD, Uy HS, Merchant A, Medina CA, Baltatzis S, Zhao T, Zhao ZS, Cantor H, Foster CS
Invest Ophthalmol Vis Sci. 2001
PubMed ID: 11581190
Nrf2-deficient female mice develop lupus-like autoimmune nephritis.
Yoh K, Itoh K, Enomoto A, Hirayama A, Yamaguchi N, Kobayashi M, Morito N, Koyama A, Yamamoto M, Takahashi S
Kidney Int. 2001
PubMed ID: 11576348
Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.
Morishima Y, Gotoh Y, Zieg J, Barrett T, Takano H, Flavell R, Davis RJ, Shirasaki Y, Greenberg ME
J Neurosci. 2001
PubMed ID: 11567045
Terminal deoxynucleotidyl transferase deficiency decreases autoimmune disease in MRL-Fas(lpr) mice.
Feeney AJ, Lawson BR, Kono DH, Theofilopoulos AN
J Immunol. 2001
PubMed ID: 11544342
Regulation of Fas ligand-induced apoptosis by TNF.
Elzey BD, Griffith TS, Herndon JM, Barreiro R, Tschopp J, Ferguson TA
J Immunol. 2001
PubMed ID: 11544288
A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis.
Huseby ES, Liggitt D, Brabb T, Schnabel B, Ohlén C, Goverman J
J Exp Med. 2001
PubMed ID: 11535634
Castration induces apoptosis in the male accessory sex organs of Fas-deficient lpr and Fas ligand-deficient gld mutant mice.
Sugihara A, Yamada N, Tsujimura T, Iwasaki T, Yamashita K, Takagi Y, Tsuji M, Terada N
In Vivo. 2001
PubMed ID: 11695234
Fas promoter -670 polymorphism is associated with development of anti-RNP antibodies in systemic lupus erythematosus.
Lee YH, Kim YR, Ji JD, Sohn J, Song GG
J Rheumatol. 2001
PubMed ID: 11550967
Inhibition of NF-kappaB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice.
Vallabhapurapu S, Ryseck RP, Malewicz M, Weih DS, Weih F
Eur J Immunol. 2001
PubMed ID: 11536159
Murine models of systemic lupus erythematosus: B and T cell responses to spliceosomal ribonucleoproteins in MRL/Fas(lpr) and (NZB x NZW)F(1) lupus mice.
Monneaux F, Dumortier H, Steiner G, Briand JP, Muller S
Int Immunol. 2001
PubMed ID: 11526096
Deficiency in beta(2)-microglobulin, but not CD1, accelerates spontaneous lupus skin disease while inhibiting nephritis in MRL-Fas(lpr) nice: an example of disease regulation at the organ level.
Chan OT, Paliwal V, McNiff JM, Park SH, Bendelac A, Shlomchik MJ
J Immunol. 2001
PubMed ID: 11509649
Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection.
Balkow S, Kersten A, Tran TT, Stehle T, Grosse P, Museteanu C, Utermöhlen O, Pircher H, von Weizsäcker F, Wallich R, Müllbacher A, Simon MM
J Virol. 2001
PubMed ID: 11507223
Fas/Fas ligand deficiency results in altered localization of anti-double-stranded DNA B cells and dendritic cells.
Fields ML, Sokol CL, Eaton-Bassiri A, Seo S, Madaio MP, Erikson J
J Immunol. 2001
PubMed ID: 11490027
TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.
Perlman R, Schiemann WP, Brooks MW, Lodish HF, Weinberg RA
Nat Cell Biol. 2001
PubMed ID: 11483955
Fas ligand (CD95L) protects neurons against perforin-mediated T lymphocyte cytotoxicity.
Medana I, Li Z, Flügel A, Tschopp J, Wekerle H, Neumann H
J Immunol. 2001
PubMed ID: 11441070
IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy.
Wigginton JM, Gruys E, Geiselhart L, Subleski J, Komschlies KL, Park JW, Wiltrout TA, Nagashima K, Back TC, Wiltrout RH
J Clin Invest. 2001
PubMed ID: 11435457
Chemokine expression precedes inflammatory cell infiltration and chemokine receptor and cytokine expression during the initiation of murine lupus nephritis.
Pérez de Lema G, Maier H, Nieto E, Vielhauer V, Luckow B, Mampaso F, Schlöndorff D
J Am Soc Nephrol. 2001
PubMed ID: 11423566
Clear suppression of Th1 responses but marginal amelioration of autoimmune manifestations by IL-12p40 transgene in MRL-FAS(lprcg)/FAS(lprcg) mice.
Yasuda T, Yoshimoto T, Tsubura A, Matsuzawa A
Cell Immunol. 2001
PubMed ID: 11520074
DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.
Kannan K, Kaminski N, Rechavi G, Jakob-Hirsch J, Amariglio N, Givol D
Oncogene. 2001
PubMed ID: 11423996
Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.
Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nägga K, Bogdanovic N, Blennow K, Brookes AJ
Eur J Hum Genet. 2001
PubMed ID: 11436125
Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice.
Nakagawa R, Nagafune I, Tazunoki Y, Ehara H, Tomura H, Iijima R, Motoki K, Kamishohara M, Seki S
J Immunol. 2001
PubMed ID: 11359810
Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
Sekine H, Reilly CM, Molano ID, Garnier G, Circolo A, Ruiz P, Holers VM, Boackle SA, Gilkeson GS
J Immunol. 2001
PubMed ID: 11342671
Fas-FasL interaction modulates nitric oxide production in Trypanosoma cruzi-infected mice.
Martins GA, Petkova SB, MacHado FS, Kitsis RN, Weiss LM, Wittner M, Tanowitz HB, Silva JS
Immunology. 2001
PubMed ID: 11380700
HIV-1 Nef: negative effector of Fas?
Xu XN, Screaton G
Nat Immunol. 2001
PubMed ID: 11323689
Evidence of a possible epigenetic inactivation mechanism operating on a region of mouse chromosome 19 in gamma-radiation-induced thymic lymphomas.
Santos J, Herranz M, Fernández M, Vaquero C, López P, Fernández-Piqueras J
Oncogene. 2001
PubMed ID: 11360203
Anti-Sm B cell differentiation in Ig transgenic MRL/Mp-lpr/lpr mice: altered differentiation and an accelerated response.
Santulli-Marotto S, Qian Y, Ferguson S, Clarke SH
J Immunol. 2001
PubMed ID: 11290816
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.
Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC
Nature. 2001
PubMed ID: 11298454
The role of Fas system [Fas-FasL] as an inducer of apoptosis in cutaneous leishmaniasis: a combined human and experimental study.
el-Kowrany SI, Sallam FA, Nassar SO, Ismail HI, Eissa MM
J Egypt Soc Parasitol. 2001
PubMed ID: 12557947
CD95 is required for the early control of parasite burden in the liver of Leishmania donovani-infected mice.
Alexander CE, Kaye PM, Engwerda CR
Eur J Immunol. 2001
PubMed ID: 11298345
Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjögren's syndrome.
Zoukhri D, Kublin CL
Invest Ophthalmol Vis Sci. 2001
PubMed ID: 11274068
The gene for a variant form of the polyadenylation protein CstF-64 is on chromosome 19 and is expressed in pachytene spermatocytes in mice.
Dass B, McMahon KW, Jenkins NA, Gilbert DJ, Copeland NG, MacDonald CC
J Biol Chem. 2001
PubMed ID: 11113135
The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair.
Hou G, Vogel W, Bendeck MP
J Clin Invest. 2001
PubMed ID: 11254672
IL-12 enhances lymphoaccumulation by suppressing cell death of T cells in MRL- lpr/lpr mice.
Xu H, Kurihara H, Ito T, Nakajima S, Hagiwara E, Yamanokuchi H, Asari A
J Autoimmun. 2001
PubMed ID: 11247634
Embryonic mouse submandibular salivary gland morphogenesis and the TNF/TNF-R1 signal transduction pathway.
Melnick M, Chen H, Zhou Y, Jaskoll T
Anat Rec. 2001
PubMed ID: 11241200
The TNF and TNF receptor superfamilies: integrating mammalian biology.
Locksley RM, Killeen N, Lenardo MJ
Cell. 2001
PubMed ID: 11239407
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
[Relationship between soluble Fas ligand levels and complications after allogeneic bone marrow transplantation]
Huang X, Wan J, Guo N, Lu D
Zhonghua Xue Ye Xue Za Zhi. 2001
PubMed ID: 11877055
Role of 14-3-3epsilon, c-Myc/Max, and Akt phosphorylation in HIV-1 gp 120-induced mesangial cell proliferation.
Kapasi AA, Fan S, Singhal PC
Am J Physiol Renal Physiol. 2001
PubMed ID: 11208609
CD8- and CD95/95L-dependent mechanisms of resistance in mice with chronic pulmonary tuberculosis.
Turner J, D'Souza CD, Pearl JE, Marietta P, Noel M, Frank AA, Appelberg R, Orme IM, Cooper AM
Am J Respir Cell Mol Biol. 2001
PubMed ID: 11159055
The role of Fas-Fas ligand-mediated apoptosis in autoimmune lacrimal gland disease in MRL/MpJ mice.
Jabs DA, Lee B, Whittum-Hudson J, Prendergast RA
Invest Ophthalmol Vis Sci. 2001
PubMed ID: 11157873
Stable expression of human immunodeficiency virus type 1 Nef confers resistance against Fas-mediated apoptosis.
Yoon K, Jeong JG, Kim S
AIDS Res Hum Retroviruses. 2001
PubMed ID: 11177389
Decreased function of Fas in patients displaying delayed progression of HIV-induced immune deficiency.
Bottarel F, Bonissoni S, Lucia MB, Bragardo M, Bensi T, Buonfiglio D, Mezzatesta C, DiFranco D, Balotta C, Capobianchi MR, Dianzani I, Cauda R, Dianzani U
Hematol J. 2001
PubMed ID: 11920253
Polymorphsims of CTLA-4 exon 1 +49, CTLA-4 promoter -318 and Fas promoter -670 in spondyloarthropathies.
Lee YH, Ji JD, Sohn J, Song GG
Clin Rheumatol. 2001
PubMed ID: 11771526
Modulation of fas/fasL in a murine retroviral infection by AZT and methionine enkephalin.
Bowden R, Soto S, Specter S
Adv Exp Med Biol. 2001
PubMed ID: 11727760
Interaction of Daxx, a Fas binding protein, with sentrin and Ubc9.
Ryu SW, Chae SK, Kim E
Biochem Biophys Res Commun. 2000
PubMed ID: 11112409
Fate of immune complexes, glomerulonephritis, and cell-mediated vasculitis in lupus-prone MRL/Mp lpr/lpr mice.
Cruse JM, Lewis RE, Dilioglou S
Exp Mol Pathol. 2000
PubMed ID: 11115362
Loss of Fas-ligand expression in mouse keratinocytes during UV carcinogenesis.
Ouhtit A, Gorny A, Muller HK, Hill LL, Owen-Schaub L, Ananthaswamy HN
Am J Pathol. 2000
PubMed ID: 11106570
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.
Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer JL, Schneider P, Seed B, Tschopp J
Nat Immunol. 2000
PubMed ID: 11101870
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity.
Siegel RM, Chan FK, Chun HJ, Lenardo MJ
Nat Immunol. 2000
PubMed ID: 11101867
Fas and Fas ligand expressed on cells of the immune system, not on the target tissue, control induction of experimental autoimmune uveitis.
Wahlsten JL, Gitchell HL, Chan CC, Wiggert B, Caspi RR
J Immunol. 2000
PubMed ID: 11067900
Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
Chen Z, Koralov SB, Kelsoe G
J Exp Med. 2000
PubMed ID: 11067882
Roles of Fas and Fas ligand during mammary gland remodeling.
Song J, Sapi E, Brown W, Nilsen J, Tartaro K, Kacinski BM, Craft J, Naftolin F, Mor G
J Clin Invest. 2000
PubMed ID: 11086022
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Immunosuppression prevents neuronal atrophy in lupus-prone mice: evidence for brain damage induced by autoimmune disease?
Sakic B, Kolb B, Whishaw IQ, Gorny G, Szechtman H, Denburg JA
J Neuroimmunol. 2000
PubMed ID: 11063826
TNF receptor 2-deficient CD8 T cells are resistant to Fas/Fas ligand-induced cell death.
Teh HS, Seebaran A, Teh SJ
J Immunol. 2000
PubMed ID: 11046004
FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.
Rochat-Steiner V, Becker K, Micheau O, Schneider P, Burns K, Tschopp J
J Exp Med. 2000
PubMed ID: 11034606
Unexpected autoantibody production in membrane Ig-mu-deficient/lpr mice.
Melamed D, Miri E, Leider N, Nemazee D
J Immunol. 2000
PubMed ID: 11035071
CD95's deadly mission in the immune system.
Krammer PH
Nature. 2000
PubMed ID: 11048730
The biochemistry of apoptosis.
Hengartner MO
Nature. 2000
PubMed ID: 11048727
apolipoprotein-E dependent role for the FAS receptor in early onset Alzheimer's disease: finding of a positive association for a polymorphism in the TNFRSF6 gene.
Feuk L, Prince JA, Breen G, Emahazion T, Carothers A, St Clair D, Brookes AJ
Hum Genet. 2000
PubMed ID: 11129341
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Fas and Fas ligand gene polymorphisms in primary Sjögren's syndrome.
Bolstad AI, Wargelius A, Nakken B, Haga HJ, Jonsson R
J Rheumatol. 2000
PubMed ID: 11036836
Inhibition of Daxx-mediated apoptosis by heat shock protein 27.
Charette SJ, Lavoie JN, Lambert H, Landry J
Mol Cell Biol. 2000
PubMed ID: 11003656
Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus.
Liang B, Kashgarian MJ, Sharpe AH, Mamula MJ
J Immunol. 2000
PubMed ID: 10975864
A novel protein (Fbf-1) that binds to CD95/APO-1/FAS and shows sequence similarity to trichohyalin and plectin.
Schmidt T, Karsunky H, Frass B, Baum W, Denzel A, Möröy T
Biochim Biophys Acta. 2000
PubMed ID: 10978533
Interferon-gamma is required for innate immunity to Cryptosporidium parvum in mice.
Hayward AR, Chmura K, Cosyns M
J Infect Dis. 2000
PubMed ID: 10950807
Genome analysis of collagen disease in MRL/lpr mice: polygenic inheritance resulting in the complex pathological manifestations.
Nose M, Terada M, Nishihara M, Kamogawa J, Miyazaki T, Qu W, Mori S, Nakatsuru S
Int J Cardiol. 2000
PubMed ID: 10980337
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.
Wei MC, Lindsten T, Mootha VK, Weiler S, Gross A, Ashiya M, Thompson CB, Korsmeyer SJ
Genes Dev. 2000
PubMed ID: 10950869
Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells.
Li Y, Kanki H, Hachiya T, Ohyama T, Irie S, Tang G, Mukai J, Sato T
Int J Cancer. 2000
PubMed ID: 10918185
Fas engagement accelerates liver regeneration after partial hepatectomy.
Desbarats J, Newell MK
Nat Med. 2000
PubMed ID: 10932231
Immune complexes present in the sera of autoimmune mice activate rheumatoid factor B cells.
Rifkin IR, Leadbetter EA, Beaudette BC, Kiani C, Monestier M, Shlomchik MJ, Marshak-Rothstein A
J Immunol. 2000
PubMed ID: 10903773
Fas and Fas ligand mutations inhibit autoantibody production in pristane-induced lupus.
Satoh M, Weintraub JP, Yoshida H, Shaheen VM, Richards HB, Shaw M, Reeves WH
J Immunol. 2000
PubMed ID: 10878381
Indispensable role for TNF-alpha and IFN-gamma at the effector phase of liver injury mediated by Th1 cells specific to hepatitis B virus surface antigen.
Ohta A, Sekimoto M, Sato M, Koda T, Nishimura S, Iwakura Y, Sekikawa K, Nishimura T
J Immunol. 2000
PubMed ID: 10878371
Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells.
Dalton DK, Haynes L, Chu CQ, Swain SL, Wittmer S
J Exp Med. 2000
PubMed ID: 10880532
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations.
Siegel RM, Frederiksen JK, Zacharias DA, Chan FK, Johnson M, Lynch D, Tsien RY, Lenardo MJ
Science. 2000
PubMed ID: 10875918
p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression.
Ivanov VN, Ronai Z
Oncogene. 2000
PubMed ID: 10871852
Double mutant MRL-lpr/lpr-gld/gld cells fail to trigger lpr-graft-versus-host disease in syngeneic wild-type recipient mice, but can induce wild-type B cells to make autoantibody.
Zhu B, Beaudette BC, Rifkin IR, Marshak-Rothstein A
Eur J Immunol. 2000
PubMed ID: 10898516
Costimulation by B7-1 and B7-2 is required for autoimmune disease in MRL-Faslpr mice.
Kinoshita K, Tesch G, Schwarting A, Maron R, Sharpe AH, Kelley VR
J Immunol. 2000
PubMed ID: 10820290
Engagement of CD4 before TCR triggering regulates both Bax- and Fas (CD95)-mediated apoptosis.
Somma F, Tuosto L, Gilardini Montani MS, Di Somma MM, Cundari E, Piccolella E
J Immunol. 2000
PubMed ID: 10799864
Proinflammatory consequences of transgenic fas ligand expression in the heart.
Nelson DP, Setser E, Hall DG, Schwartz SM, Hewitt T, Klevitsky R, Osinska H, Bellgrau D, Duke RC, Robbins J
J Clin Invest. 2000
PubMed ID: 10791994
Increased TUNEL staining in brains of autoimmune Fas-deficient mice.
Sakic B, Maric I, Koeberle PD, Millward JM, Szechtman H, Maric D, Denburg JA
J Neuroimmunol. 2000
PubMed ID: 10713354
Systemic lupus erythematosus in mice, spontaneous and induced, is associated with autoimmunity to the C-terminal domain of p53 that recognizes damaged DNA.
Herkel J, Erez-Alon N, Mimran A, Wolkowicz R, Harmelin A, Ruiz P, Rotter V, Cohen IR
Eur J Immunol. 2000
PubMed ID: 10760784
Rapid B cell apoptosis induced by antigen receptor ligation does not require Fas (CD95/APO-1), the adaptor protein FADD/MORT1 or CrmA-sensitive caspases but is defective in both MRL-+/+ and MRL-lpr/lpr mice.
Yoshida T, Higuchi T, Hagiyama H, Strasser A, Nishioka K, Tsubata T
Int Immunol. 2000
PubMed ID: 10744653
Kappa-deficient mice are non-responders to dextran B512: is this unresponsiveness due to specialization of the kappa and lambda Ig repertoires?
Sverremark E, Rietz C, Fernández C
Int Immunol. 2000
PubMed ID: 10744644
A membrane-bound Fas decoy receptor expressed by human thymocytes.
Jenkins M, Keir M, McCune JM
J Biol Chem. 2000
PubMed ID: 10713117
Tumor immunity in perforin-deficient mice: a role for CD95 (Fas/APO-1).
Rosen D, Li JH, Keidar S, Markon I, Orda R, Berke G
J Immunol. 2000
PubMed ID: 10706715
CD95 (Fas/APO-1) and p53 signal apoptosis independently in diverse cell types.
O'Connor L, Harris AW, Strasser A
Cancer Res. 2000
PubMed ID: 10728678
Fas and Fas ligand in gut and liver.
Pinkoski MJ, Brunner T, Green DR, Lin T
Am J Physiol Gastrointest Liver Physiol. 2000
PubMed ID: 10712254
Th1 versus Th2 immune responses in autoimmune lacrimal gland disease in MRL/Mp mice.
Jabs DA, Lee B, Whittum-Hudson JA, Prendergast RA
Invest Ophthalmol Vis Sci. 2000
PubMed ID: 10711700
Autoimmune lymphoproliferative syndrome (ALPS) in a child from consanguineous parents: a dominant or recessive disease?
van der Burg M, de Groot R, Comans-Bitter WM, den Hollander JC, Hooijkaas H, Neijens HJ, Berger RM, Oranje AP, Langerak AW, van Dongen JJ
Pediatr Res. 2000
PubMed ID: 10709732
Improved generation of catalytic antibodies by MRL/MPJ-lpr/lpr autoimmune mice.
Takahashi N, Kakinuma H, Hamada K, Shimazaki K, Yamasaki Y, Matsushita H, Nishi Y
J Immunol Methods. 2000
PubMed ID: 10675763
APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death.
Kelly K, Manos E, Jensen G, Nadauld L, Jones DA
Cancer Res. 2000
PubMed ID: 10706119
TNF-alpha is the critical mediator of the cyclic AMP-induced apoptosis of CD8+4+ double-positive thymocytes.
Guevara Patiño JA, Ivanov VN, Lacy E, Elkon KB, Marino MW, Nikolic-Zugić J
J Immunol. 2000
PubMed ID: 10657611
TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions.
Nguyen LT, McKall-Faienza K, Zakarian A, Speiser DE, Mak TW, Ohashi PS
Eur J Immunol. 2000
PubMed ID: 10671227
T cell activation-induced and HIV tat-enhanced CD95(APO-1/Fas) ligand transcription involves NF-kappaB.
Li-Weber M, Laur O, Dern K, Krammer PH
Eur J Immunol. 2000
PubMed ID: 10671224
Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
Reilly CM, Oates JC, Cook JA, Morrow JD, Halushka PV, Gilkeson GS
J Immunol. 2000
PubMed ID: 10640767
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Watanabe H, Garnier G, Circolo A, Wetsel RA, Ruiz P, Holers VM, Boackle SA, Colten HR, Gilkeson GS
J Immunol. 2000
PubMed ID: 10623824
Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis.
Micoli KJ, Pan G, Wu Y, Williams JP, Cook WJ, McDonald JM
J Biol Chem. 2000
PubMed ID: 10625668
Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy.
Newton K, Strasser A
J Exp Med. 2000
PubMed ID: 10620618
Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotype.
Körner H, Cretney E, Wilhelm P, Kelly JM, Röllinghoff M, Sedgwick JD, Smyth MJ
J Exp Med. 2000
PubMed ID: 10620607
The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis.
Charette SJ, Landry J
Ann N Y Acad Sci. 2000
PubMed ID: 11193028
Genetic basis of the complex pathological manifestations of collagen disease: lessons from MRL/lpr and related mouse models.
Nose M, Nishihara M, Fujii H
Int Rev Immunol. 2000
PubMed ID: 11016428
Immunological characterization of C3H mice congenic for Fas(lprcg), C3h/HeJ-Fas(lprcg)/Fas(lprcg).
Yasuda T, Zhang Y, Nagase H, Kaneko T, Sayama K, Hashimoto H, Matsuzawa A
Lab Anim. 2000
PubMed ID: 10759366
Soluble Fas in serum from patients with renal cell carcinoma.
Nonomura N, Nishimura K, Ono Y, Fukui T, Harada Y, Takaha N, Takahara S, Okuyama A
Urology. 2000
PubMed ID: 10654915
Ionizing radiation alters Fas antigen ligand at the cell surface and on exfoliated plasma membrane-derived vesicles: implications for apoptosis and intercellular signaling.
Albanese J, Dainiak N
Radiat Res. 2000
PubMed ID: 10630977
Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar.
Lee SH, Shin MS, Kim HS, Park WS, Kim SY, Jang JJ, Rhim KJ, Jang J, Lee HK, Park JY, Oh RR, Han SY, Lee JH, Lee JY, Yoo NJ
J Invest Dermatol. 2000
PubMed ID: 10620127
Effect of a genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production by C57BL6 Fas(lpr) mice.
Molano ID, Wloch MK, Alexander AA, Watanabe H, Gilkeson GS
Clin Immunol. 2000
PubMed ID: 10607487
IL-12 drives IFN-gamma-dependent autoimmune kidney disease in MRL-Fas(lpr) mice.
Schwarting A, Tesch G, Kinoshita K, Maron R, Weiner HL, Kelley VR
J Immunol. 1999
PubMed ID: 10586090
Alterations in hypothalamic-pituitary-adrenal function correlated with the onset of murine SLE in MRL +/+ and lpr/lpr mice.
Shanks N, Moore PM, Perks P, Lightman SL
Brain Behav Immun. 1999
PubMed ID: 10600221
Abnormal thymic expression of epithelial cell adhesion molecule (EP-CAM) in New Zealand Black (NZB) mice.
Taguchi N, Hashimoto Y, Naiki M, Farr AG, Boyd RL, Ansari AA, Shultz LD, Kotzin BL, Dorshkind K, Ikehara S, Gershwin ME
J Autoimmun. 1999
PubMed ID: 10585755
Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway.
Ashany D, Savir A, Bhardwaj N, Elkon KB
J Immunol. 1999
PubMed ID: 10553053
Activation of Hex and mEg5 by retroviral insertion may contribute to mouse B-cell leukemia.
Hansen GM, Justice MJ
Oncogene. 1999
PubMed ID: 10597256
F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis.
Chan SL, Tan KO, Zhang L, Yee KS, Ronca F, Chan MY, Yu VC
J Biol Chem. 1999
PubMed ID: 10542291
Gender- and androgen-related influence on the expression of proto-oncogene and apoptotic factor mRNAs in lacrimal glands of autoimmune and non-autoimmune mice.
Toda I, Sullivan BD, Wickham LA, Sullivan DA
J Steroid Biochem Mol Biol. 1999
PubMed ID: 10619357
Genetic dissection of the complex pathological manifestations of collagen disease in MRL/lpr mice.
Nakatsuru S, Terada M, Nishihara M, Kamogawa J, Miyazaki T, Qu WM, Morimoto K, Yazawa C, Ogasawara H, Abe Y, Fukui K, Ichien G, Ito MR, Mori S, Nakamura Y, Nose M
Pathol Int. 1999
PubMed ID: 10594844
The effect on immunoglobulin glycosylation of altering in vivo production of immunoglobulin G.
Jeddi P, Keusch J, Lydyard PM, Bodman-Smith KB, Chesnutt MS, Wofsy D, Hirota H, Taga T, Delves PJ
Immunology. 1999
PubMed ID: 10583610
Apoptosis and the thymic microenvironment in murine lupus.
Takeoka Y, Taguchi N, Shultz L, Boyd RL, Naiki M, Ansari AA, Gershwin ME
J Autoimmun. 1999
PubMed ID: 10550220
LFG: an anti-apoptotic gene that provides protection from Fas-mediated cell death.
Somia NV, Schmitt MJ, Vetter DE, Van Antwerp D, Heinemann SF, Verma IM
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10535980
Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity.
Kamath AB, Camacho I, Nagarkatti PS, Nagarkatti M
Toxicol Appl Pharmacol. 1999
PubMed ID: 10527913
Increased fetal and extramedullary hematopoiesis in Fas-deficient C57BL/6-lpr/lpr mice.
Schneider E, Moreau G, Arnould A, Vasseur F, Khodabaccus N, Dy M, Ezine S
Blood. 1999
PubMed ID: 10515865
Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations.
Rieux-Laucat F, Blachère S, Danielan S, De Villartay JP, Oleastro M, Solary E, Bader-Meunier B, Arkwright P, Pondaré C, Bernaudin F, Chapel H, Nielsen S, Berrah M, Fischer A, Le Deist F
Blood. 1999
PubMed ID: 10515860
Regulation of acidification and apoptosis by SHP-1 and Bcl-2.
Thangaraju M, Sharma K, Leber B, Andrews DW, Shen SH, Srikant CB
J Biol Chem. 1999
PubMed ID: 10506221
Polarized expression of immunoglobulin, spectrin, and protein kinase C beta II occurs in B cells from normal BALB/c, autoimmune lpr, and anti-ssDNA transgenic, tolerant mice.
Masso-Welch PA, Black JD, Erikson J, Repasky EA
J Leukoc Biol. 1999
PubMed ID: 10534118
Expression in transgenic mice of dominant interfering Fas mutations: a model for human autoimmune lymphoproliferative syndrome.
Choi Y, Ramnath VR, Eaton AS, Chen A, Simon-Stoos KL, Kleiner DE, Erikson J, Puck JM
Clin Immunol. 1999
PubMed ID: 10497009
IL-5 mediates eosinophilic rejection of MHC class II-disparate skin allografts in mice.
Le Moine A, Surquin M, Demoor FX, Noël JC, Nahori MA, Pretolani M, Flamand V, Braun MY, Goldman M, Abramowicz D
J Immunol. 1999
PubMed ID: 10490975
Impaired Fas response and autoimmunity in Pten+/- mice.
Di Cristofano A, Kotsi P, Peng YF, Cordon-Cardo C, Elkon KB, Pandolfi PP
Science. 1999
PubMed ID: 10497129
The cell death-inducing ability of glycoprotein 120 from different HIV strains correlates with their ability to induce CD4 lateral association with CD95 on CD4+ T cells.
Bottarel F, Feito MJ, Bragardo M, Bonissoni S, Buonfiglio D, DeFranco S, Malavasi F, Bensi T, Ramenghi U, Dianzani U
AIDS Res Hum Retroviruses. 1999
PubMed ID: 10505674
Role of the costimulatory molecule CD28 in the development of lupus in MRL/lpr mice.
Tada Y, Nagasawa K, Ho A, Morito F, Koarada S, Ushiyama O, Suzuki N, Ohta A, Mak TW
J Immunol. 1999
PubMed ID: 10477582
Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice.
Brard F, Shannon M, Prak EL, Litwin S, Weigert M
J Exp Med. 1999
PubMed ID: 10477553
Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice.
Wang H, Shlomchik MJ
J Exp Med. 1999
PubMed ID: 10477549
B7 costimulation in the development of lupus: autoimmunity arises either in the absence of B7.1/B7.2 or in the presence of anti-b7.1/B7.2 blocking antibodies.
Liang B, Gee RJ, Kashgarian MJ, Sharpe AH, Mamula MJ
J Immunol. 1999
PubMed ID: 10438978
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
Nishimura H, Nose M, Hiai H, Minato N, Honjo T
Immunity. 1999
PubMed ID: 10485649
Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively.
Hashimoto W, Osaki T, Okamura H, Robbins PD, Kurimoto M, Nagata S, Lotze MT, Tahara H
J Immunol. 1999
PubMed ID: 10395644
Several different cell surface molecules control negative selection of medullary thymocytes.
Kishimoto H, Sprent J
J Exp Med. 1999
PubMed ID: 10429671
Another cell death induction system: TNF-alpha acts as a ligand for Fas in vaginal cells.
Suzuki A, Tsutomi Y, Shimizu M, Matsuzawa A
Cell Death Differ. 1999
PubMed ID: 10453074
The modular nature of apoptotic signaling proteins.
Hofmann K
Cell Mol Life Sci. 1999
PubMed ID: 10442092
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis.
Kuwano K, Hagimoto N, Kawasaki M, Yatomi T, Nakamura N, Nagata S, Suda T, Kunitake R, Maeyama T, Miyazaki H, Hara N
J Clin Invest. 1999
PubMed ID: 10393694
Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice.
Goulet JL, Griffiths RC, Ruiz P, Spurney RF, Pisetsky DS, Koller BH, Coffman TM
J Immunol. 1999
PubMed ID: 10384136
Severe impairment of B cell function in lpr/lpr mice expressing transgenic Fas selectively on B cells.
Komano H, Ikegami Y, Yokoyama M, Suzuki R, Yonehara S, Yamasaki Y, Shinohara N
Int Immunol. 1999
PubMed ID: 10383935
MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells.
Mandik-Nayak L, Seo SJ, Sokol C, Potts KM, Bui A, Erikson J
J Exp Med. 1999
PubMed ID: 10359584
Ectopic expression of B7-1 (CD80) on T lymphocytes in autoimmune lpr and gld mice.
Weintraub JP, Cohen PL
Clin Immunol. 1999
PubMed ID: 10370375
Evidence for Fas-dependent and Fas-independent mechanisms in the pathogenesis of experimental autoimmune encephalomyelitis.
Dittel BN, Merchant RM, Janeway CA
J Immunol. 1999
PubMed ID: 10352252
Defective apoptosis due to a point mutation in the death domain of CD95 associated with autoimmune lymphoproliferative syndrome, T-cell lymphoma, and Hodgkin's disease.
Peters AM, Kohfink B, Martin H, Griesinger F, Wörmann B, Gahr M, Roesler J
Exp Hematol. 1999
PubMed ID: 10340403
Retroviral insertions in Evi12, a novel common virus integration site upstream of Tra1/Grp94, frequently coincide with insertions in the gene encoding the peripheral cannabinoid receptor Cnr2.
Valk PJ, Vankan Y, Joosten M, Jenkins NA, Copeland NG, Löwenberg B, Delwel R
J Virol. 1999
PubMed ID: 10196250
The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis.
Imai Y, Kimura T, Murakami A, Yajima N, Sakamaki K, Yonehara S
Nature. 1999
PubMed ID: 10235259
A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiation.
Hill LL, Shreedhar VK, Kripke ML, Owen-Schaub LB
J Exp Med. 1999
PubMed ID: 10209045
Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis.
Sabelko-Downes KA, Cross AH, Russell JH
J Exp Med. 1999
PubMed ID: 10209037
Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.
Martin DA, Zheng L, Siegel RM, Huang B, Fisher GH, Wang J, Jackson CE, Puck JM, Dale J, Straus SE, Peter ME, Krammer PH, Fesik S, Lenardo MJ
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10200300
Mice with early onset of death (EOD) due to lupus glomerulonephritis.
Honda S, Nemoto K, Mae T, Kinjoh K, Kyogoku M, Kawamura H, Miyazawa S, Weerashinghe A, Watanabe H, Narita J, Koya T, Arakawa M, Abo T
Clin Exp Immunol. 1999
PubMed ID: 10209520
Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance.
Jackson CE, Fischer RE, Hsu AP, Anderson SM, Choi Y, Wang J, Dale JK, Fleisher TA, Middelton LA, Sneller MC, Lenardo MJ, Straus SE, Puck JM
Am J Hum Genet. 1999
PubMed ID: 10090885
Tumor necrosis factor-alpha and CD95 ligation suppress erythropoiesis in Fanconi anemia C gene knockout mice.
Otsuki T, Nagakura S, Wang J, Bloom M, Grompe M, Liu JM
J Cell Physiol. 1999
PubMed ID: 10082135
IL-2-dependent expression of genes involved in cytoskeleton organization, oncogene regulation, and transcriptional control.
Herblot S, Chastagner P, Samady L, Moreau JL, Demaison C, Froussard P, Liu X, Bonnet J, Thèze J
J Immunol. 1999
PubMed ID: 10092780
Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8.
Bartz SR, Emerman M
J Virol. 1999
PubMed ID: 9971775
Fas ligand (CD95 ligand) controls angiogenesis beneath the retina.
Kaplan HJ, Leibole MA, Tezel T, Ferguson TA
Nat Med. 1999
PubMed ID: 10086384
A tailless fas-FADD death-effector domain chimera is sufficient to execute Fas function in T cells but not B cells of MRL-lpr/lpr mice.
Kabra NH, Cado D, Winoto A
J Immunol. 1999
PubMed ID: 10072523
Potent inhibition of CD4/TCR-mediated T cell apoptosis by a CD4-binding glycoprotein secreted from breast tumor and seminal vesicle cells.
Gaubin M, Autiero M, Basmaciogullari S, Métivier D, Mis hal Z, Culerrier R, Oudin A, Guardiola J, Piatier-Tonneau D
J Immunol. 1999
PubMed ID: 10072505
A mouse chromosome 19 genetic map including the Lvis1 viral insertion site.
Hansen GM, Tackles D, Schwartz C, Justice MJ
Genomics. 1999
PubMed ID: 10051411
Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity.
Kehren J, Desvignes C, Krasteva M, Ducluzeau MT, Assossou O, Horand F, Hahne M, Kägi D, Kaiserlian D, Nicolas JF
J Exp Med. 1999
PubMed ID: 10049941
Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model : interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis.
Gu L, Johnson MW, Lusis AJ
Arterioscler Thromb Vasc Biol. 1999
PubMed ID: 9974430
Timing and casting for actors of thymic negative selection.
Dautigny N, Le Campion A, Lucas B
J Immunol. 1999
PubMed ID: 9973382
The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations.
Vaishnaw AK, Orlinick JR, Chu JL, Krammer PH, Chao MV, Elkon KB
J Clin Invest. 1999
PubMed ID: 9927496
Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway.
Zauli G, Gibellini D, Secchiero P, Dutartre H, Olive D, Capitani S, Collette Y
Blood. 1999
PubMed ID: 9920849
Sjögren's syndrome in mice carrying the Ipr(cg) gene and the therapeutic efficacy of an immunosuppressive agent FK506.
Yang J, Shikata N, Yasuda T, Matsuzawa A, Tsubura A
Pathol Int. 1999
PubMed ID: 10355966
Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells.
Mittelstadt PR, Ashwell JD
J Biol Chem. 1999
PubMed ID: 9915863
Vpu increases susceptibility of human immunodeficiency virus type 1-infected cells to fas killing.
Casella CR, Rapaport EL, Finkel TH
J Virol. 1999
PubMed ID: 9847311
Lack of FGF-1 overexpression during autoimmune nephritis in the kidneys of MRL lpr/lpr mice.
Madiai F, Hackshaw KV
Res Commun Mol Pathol Pharmacol. 1999
PubMed ID: 10440569
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Genetic determinants of autoimmune disease and coronary vasculitis in the MRL-lpr/lpr mouse model of systemic lupus erythematosus.
Gu L, Weinreb A, Wang XP, Zack DJ, Qiao JH, Weisbart R, Lusis AJ
J Immunol. 1998
PubMed ID: 9862736
Coordinate up-regulation of the beta-chemokine subfamily in autoimmune sialoadenitis of MRL/lpr mice.
Mustafa W, Sharafeldin A, Diab A, Huang YM, Bing H, Zhu J, Link H, Frithiof L, Klinge B
Scand J Immunol. 1998
PubMed ID: 9874496
Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of Fas.
Fogler WE, Volker K, Watanabe M, Wigginton JM, Roessler P, Brunda MJ, Ortaldo JR, Wiltrout RH
J Immunol. 1998
PubMed ID: 9834083
Acute hepatotoxicity of Pseudomonas aeruginosa exotoxin A in mice depends on T cells and TNF.
Schümann J, Angermüller S, Bang R, Lohoff M, Tiegs G
J Immunol. 1998
PubMed ID: 9820556
Acceleration of lpr lymphoproliferative and autoimmune disease by transgenic protein kinase CK2 alpha.
Rifkin IR, Channavajhala PL, Kiefer HL, Carmack AJ, Landesman-Bollag E, Beaudette BC, Jersky B, Salant DJ, Ju ST, Marshak-Rothstein A, Seldin DC
J Immunol. 1998
PubMed ID: 9820486
Fas and Fas ligand interactions suppress melanoma lung metastasis.
Owen-Schaub LB, van Golen KL, Hill LL, Price JE
J Exp Med. 1998
PubMed ID: 9802983
Aberrant expression and dysfunction of Fas antigen in MRL/MpJ-lpr/lpr murine ovary.
Xu JP, Li X, Mori E, Guo MW, Mori T
Zygote. 1998
PubMed ID: 9921647
Antitumor activity exhibited by Fas ligand (CD95L) overexpressed on lymphoid cells against Fas+ tumor cells.
Shimizu M, Takeda Y, Yagita H, Yoshimoto T, Matsuzawa A
Cancer Immunol Immunother. 1998
PubMed ID: 9829839
Expression of Th1/Th2 cytokine mRNA in peritoneal exudative polymorphonuclear neutrophils and their effects on mononuclear cell Th1/Th2 cytokine production in MRL-lpr/lpr mice.
Yu C, Sun K, Tsai C, Tsai Y, Tsai S, Huang D, Han S, Yu H
Immunology. 1998
PubMed ID: 9824514
The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis.
Infante AJ, Britton HA, DeNapoli T, Middelton LA, Lenardo MJ, Jackson CE, Wang J, Fleisher T, Straus SE, Puck JM
J Pediatr. 1998
PubMed ID: 9821419
Expression and function of Fas on cells damaged by gamma-irradiation in B6 and B6/lpr mice.
Booker JK, Reap EA, Cohen PL
J Immunol. 1998
PubMed ID: 9794379
Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity.
Grønbaek K, Straten PT, Ralfkiaer E, Ahrenkiel V, Andersen MK, Hansen NE, Zeuthen J, Hou-Jensen K, Guldberg P
Blood. 1998
PubMed ID: 9787134
Vasculitis-susceptible genes in mice with a deficit in Fas-mediated apoptosis.
Nose M, Terada M, Nishihara M, Kamogawa J, Miyazaki T, Mori S, Nishimura M, Wang Y, Kamoto T, Hiai H
Int J Cardiol. 1998
PubMed ID: 9951801
Radiation kills human peripheral T cells by a Fas-independent mechanism.
Ogawa Y, Nishioka A, Inomata T, Yoshida S, Nakayama KI, Kataoka S
Int J Mol Med. 1998
PubMed ID: 9857224
Main-chain signal assignment for the PDZ2 domain from human protein tyrosine phosphatase hPTP1E and its complex with a C-terminal peptide from the Fas receptor.
Ekiel I, Banville D, Shen SH, Slon-Usakiewicz JJ, Koshy A, Gehring K
J Biomol NMR. 1998
PubMed ID: 9835052
Apoptosis mediated by Fas but not tumor necrosis factor receptor 1 prevents chronic disease in mice infected with murine cytomegalovirus.
Fleck M, Kern ER, Zhou T, Podlech J, Wintersberger W, Edwards CK, Mountz JD
J Clin Invest. 1998
PubMed ID: 9769336
Oxygen toxicity in mouse lung: pathways to cell death.
Barazzone C, Horowitz S, Donati YR, Rodriguez I, Piguet PF
Am J Respir Cell Mol Biol. 1998
PubMed ID: 9761753
Apoptotic regulation of T cells and absence of immune deficiency in virus-infected gamma interferon receptor knockout mice.
Lohman BL, Welsh RM
J Virol. 1998
PubMed ID: 9733817
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis.
Uckun FM
Biochem Pharmacol. 1998
PubMed ID: 9751072
Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome.
Rafi AQ, Zeytun A, Bradley MJ, Sponenberg DP, Grayson RL, Nagarkatti M, Nagarkatti PS
J Immunol. 1998
PubMed ID: 9743374
Perforin-dependent neurologic injury in a viral model of multiple sclerosis.
Murray PD, McGavern DB, Lin X, Njenga MK, Leibowitz J, Pease LR, Rodriguez M
J Neurosci. 1998
PubMed ID: 9736651
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade.
Juo P, Kuo CJ, Yuan J, Blenis J
Curr Biol. 1998
PubMed ID: 9740801
Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis.
Gao Y, Herndon JM, Zhang H, Griffith TS, Ferguson TA
J Exp Med. 1998
PubMed ID: 9730890
Death receptors: signaling and modulation.
Ashkenazi A, Dixit VM
Science. 1998
PubMed ID: 9721089
Mice deficient in fas ligand (gld) or fas (lpr) show few alterations in granulopoiesis.
Fecho K, Bentley SA, Cohen PL
Cell Immunol. 1998
PubMed ID: 9743554
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.
Li H, Zhu H, Xu CJ, Yuan J
Cell. 1998
PubMed ID: 9727492
IL-2 receptor alpha-chain expression is independently regulated in primary and secondary lymphoid organs.
Demaison C, Fiette L, Blanchetière V, Schimpl A, Thèze J, Froussard P
J Immunol. 1998
PubMed ID: 9712069
TCR ligation on CD8+ T cells creates double-negative cells in vivo.
Mehal WZ, Crispe IN
J Immunol. 1998
PubMed ID: 9712032
Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia.
Traver D, Akashi K, Weissman IL, Lagasse E
Immunity. 1998
PubMed ID: 9697835
IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice.
Schwarting A, Wada T, Kinoshita K, Tesch G, Kelley VR
J Immunol. 1998
PubMed ID: 9647261
Sp3 regulates fas expression in lung epithelial cells.
Pang H, Miranda K, Fine A
Biochem J. 1998
PubMed ID: 9639581
An allogeneic microenvironment influences the phenotype of intermediate T-cell receptor cells expanding in MRL-lpr/lpr mice.
Tsukahara A, Iiai T, Moroda T, Tada T, Suzuki S, Takeda K, Hatakeyama K, Abo T
Immunology. 1998
PubMed ID: 9741335
Effect of age and apoptosis on the mouse homologue of the huWRN gene.
Wu J, He J, Mountz JD
Mech Ageing Dev. 1998
PubMed ID: 9681877
Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions.
Davidson WF, Giese T, Fredrickson TN
J Exp Med. 1998
PubMed ID: 9607923
Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity.
Lin X, Pease LR, Murray PD, Rodriguez M
J Immunol. 1998
PubMed ID: 9605173
Immunological and pathological consequences of mutations in both Fas and Fas ligand.
Weintraub JP, Godfrey V, Wolthusen PA, Cheek RL, Eisenberg RA, Cohen PL
Cell Immunol. 1998
PubMed ID: 9637760
A role for Fas in negative selection of thymocytes in vivo.
Kishimoto H, Surh CD, Sprent J
J Exp Med. 1998
PubMed ID: 9565635
Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production.
Huang FP, Xu D, Esfandiari EO, Sands W, Wei XQ, Liew FY
J Immunol. 1998
PubMed ID: 9574511
ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases.
Koseki T, Inohara N, Chen S, Núñez G
Proc Natl Acad Sci U S A. 1998
PubMed ID: 9560245
IFN-gamma limits macrophage expansion in MRL-Fas(lpr) autoimmune interstitial nephritis: a negative regulatory pathway.
Schwarting A, Moore K, Wada T, Tesch G, Yoon HJ, Kelley VR
J Immunol. 1998
PubMed ID: 9558118
Fas/Fas ligand signaling during gestational T cell development.
Fleck M, Zhou T, Tatsuta T, Yang P, Wang Z, Mountz JD
J Immunol. 1998
PubMed ID: 9558079
Enhanced lymphoproliferation and diminished autoimmunity in CD4-deficient MRL/lpr mice.
Chesnutt MS, Finck BK, Killeen N, Connolly MK, Goodman H, Wofsy D
Clin Immunol Immunopathol. 1998
PubMed ID: 9576007
The primary site of CD4- 8- B220+ alphabeta T cells in lpr mice: the appendix in normal mice.
Yamagiwa S, Sugahara S, Shimizu T, Iwanaga T, Yoshida Y, Honda S, Watanabe H, Suzuki K, Asakura H, Abo T
J Immunol. 1998
PubMed ID: 9510165
Induction of immune-mediated hearing loss in SCID mice by injection of MRL/lpr mouse spleen cells.
Iwai H, Tomoda K, Hosaka N, Miyashima S, Suzuka Y, Ikeda H, Lee S, Inaba M, Ikehara S, Yamashita T
Hear Res. 1998
PubMed ID: 9557987
Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes.
Van Parijs L, Biuckians A, Abbas AK
J Immunol. 1998
PubMed ID: 9498742
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes.
Newton K, Harris AW, Bath ML, Smith KG, Strasser A
EMBO J. 1998
PubMed ID: 9450996
Proliferation of CD3+ B220- single-positive normal T cells was suppressed in B-cell-deficient lpr mice.
Akashi T, Nagafuchi S, Anzai K, Kitamura D, Wang J, Taniuchi I, Niho Y, Watanabe T
Immunology. 1998
PubMed ID: 9616374
Perforin protects against autoimmunity in lupus-prone mice.
Peng SL, Moslehi J, Robert ME, Craft J
J Immunol. 1998
PubMed ID: 9551899
Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells.
Noble A, Pestano GA, Cantor H
J Immunol. 1998
PubMed ID: 9551888
Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice.
Balomenos D, Rumold R, Theofilopoulos AN
J Clin Invest. 1998
PubMed ID: 9435308
Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction.
Wajant H, Johannes FJ, Haas E, Siemienski K, Schwenzer R, Schubert G, Weiss T, Grell M, Scheurich P
Curr Biol. 1998
PubMed ID: 9427646
Gene structure and chromosome location of mouse Cd39 coding for an ecto-apyrase.
Schoenborn MA, Jenkins NA, Copeland NG, Gilbert DJ, Gayle RB, Maliszewski CR
Cytogenet Cell Genet. 1998
PubMed ID: 9730622
A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice.
Chan O, Shlomchik MJ
J Immunol. 1998
PubMed ID: 9551955
The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicity.
Conceição-Silva F, Hahne M, Schröter M, Louis J, Tschopp J
Eur J Immunol. 1998
PubMed ID: 9485203
HIV-1 gp120 accelerates Fas-mediated activation-induced human lamina propria T cell apoptosis.
Boirivant M, Viora M, Giordani L, Luzzati AL, Pronio AM, Montesani C, Pugliese O
J Clin Immunol. 1998
PubMed ID: 9475352
Pathogenesis of autoimmunity in alphabeta T cell-deficient lupus-prone mice.
Peng SL, Cappadona J, McNiff JM, Madaio MP, Owen MJ, Hayday AC, Craft J
Clin Exp Immunol. 1998
PubMed ID: 9472669
Thymocyte glucocorticoid resistance alters positive selection and inhibits autoimmunity and lymphoproliferative disease in MRL-lpr/lpr mice.
Tolosa E, King LB, Ashwell JD
Immunity. 1998
PubMed ID: 9462512
Gender and androgen treatment influence the expression of proto-oncogenes and apoptotic factors in lacrimal and salivary tissues of MRL/lpr mice.
Toda I, Wickham LA, Sullivan DA
Clin Immunol Immunopathol. 1998
PubMed ID: 9434797
Amelioration of systemic autoimmune disease by the stimulation of apoptosis-promoting receptor Fas with anti-Fas mAb.
Nishimura-Morita Y, Nose M, Inoue T, Yonehara S
Int Immunol. 1997
PubMed ID: 9466307
Myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas- and Fas ligand-deficient lpr and gld mice.
Malipiero U, Frei K, Spanaus KS, Agresti C, Lassmann H, Hahne M, Tschopp J, Eugster HP, Fontana A
Eur J Immunol. 1997
PubMed ID: 9464800
Why do defects in the Fas-Fas ligand system cause autoimmunity?
Suda T, Nagata S
J Allergy Clin Immunol. 1997
PubMed ID: 9440553
[Primary study on Fas-mediated apoptosis in the liver tissue of patients with chronic hepatitis B]
Zhu K, Zhang L, Wang H, Wang S, Wang L, Pan Q
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 1997
PubMed ID: 15617242
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis.
Hueber AO, Zörnig M, Lyon D, Suda T, Nagata S, Evan GI
Science. 1997
PubMed ID: 9360929
TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival.
Lee SY, Reichlin A, Santana A, Sokol KA, Nussenzweig MC, Choi Y
Immunity. 1997
PubMed ID: 9390693
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL.
MacFarlane M, Ahmad M, Srinivasula SM, Fernandes-Alnemri T, Cohen GM, Alnemri ES
J Biol Chem. 1997
PubMed ID: 9325248
Apoptosis in the cornea: further characterization of Fas/Fas ligand system.
Mohan RR, Liang Q, Kim WJ, Helena MC, Baerveldt F, Wilson SE
Exp Eye Res. 1997
PubMed ID: 9464190
Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis.
Pensati L, Costanzo A, Ianni A, Accapezzato D, Iorio R, Natoli G, Nisini R, Almerighi C, Balsano C, Vajro P, Vegnente A, Levrero M
Gastroenterology. 1997
PubMed ID: 9322534
Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis.
Waldner H, Sobel RA, Howard E, Kuchroo VK
J Immunol. 1997
PubMed ID: 9317104
The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo.
Reinke V, Lozano G
Oncogene. 1997
PubMed ID: 9380404
Transcription factor Egr-1 activity down-regulates Fas and CD23 expression in B cells.
Dinkel A, Aicher WK, Haas C, Zipfel PF, Peter HH, Eibel H
J Immunol. 1997
PubMed ID: 9300687
Suppression of autoimmune disease and of massive lymphadenopathy in MRL/Mp-lpr/lpr mice lacking tyrosine kinase Fyn (p59fyn).
Takahashi T, Yagi T, Kakinuma S, Kurokawa A, Okada T, Takatsu K, Aizawa S, Katagiri T
J Immunol. 1997
PubMed ID: 9278347
Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus.
Lloyd CM, Gonzalo JA, Salant DJ, Just J, Gutierrez-Ramos JC
J Clin Invest. 1997
PubMed ID: 9276713
[Core protein of hepatitis C virus expressed in transgenic mice is associated with the expression of Fas molecule]
Tan W, Lang Z, Cong Y, Chen G, Miao J, Zhan M
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 1997
PubMed ID: 15617329
Immunosensitization of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity.
Frost P, Ng CP, Belldegrun A, Bonavida B
Cell Immunol. 1997
PubMed ID: 9316641
Human immunodeficiency virus type 1 TAT protein activates B lymphocytes.
Huang L, Li CJ, Pardee AB
Biochem Biophys Res Commun. 1997
PubMed ID: 9268734
Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas(lpr) mice from early lethality.
Bullard DC, King PD, Hicks MJ, Dupont B, Beaudet AL, Elkon KB
J Immunol. 1997
PubMed ID: 9257874
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X
Cell. 1997
PubMed ID: 9267021
Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2.
Gilkeson GS, Mudgett JS, Seldin MF, Ruiz P, Alexander AA, Misukonis MA, Pisetsky DS, Weinberg JB
J Exp Med. 1997
PubMed ID: 9236188
Immunohistochemical analysis of murine CD95/Fas/Apo-1 receptor and its ultrastructural distribution in the thymus.
Ramos P, Gangi MD, Baren A, Filippa D, Elkon KB
APMIS. 1997
PubMed ID: 9298096
Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta.
Moser M, Pscherer A, Roth C, Becker J, Mücher G, Zerres K, Dixkens C, Weis J, Guay-Woodford L, Buettner R, Fässler R
Genes Dev. 1997
PubMed ID: 9271117
gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules.
Feito MJ, Bragardo M, Buonfiglio D, Bonissoni S, Bottarel F, Malavasi F, Dianzani U
Int Immunol. 1997
PubMed ID: 9263011
Mouse complement receptors type 1 (CR1;CD35) and type 2 (CR2;CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice.
Takahashi K, Kozono Y, Waldschmidt TJ, Berthiaume D, Quigg RJ, Baron A, Holers VM
J Immunol. 1997
PubMed ID: 9233655
Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice.
Piredda L, Amendola A, Colizzi V, Davies PJ, Farrace MG, Fraziano M, Gentile V, Uray I, Piacentini M, Fesus L
Cell Death Differ. 1997
PubMed ID: 16465267
Characterization of Fas (Apo-1, CD95)-Fas ligand interaction.
Schneider P, Bodmer JL, Holler N, Mattmann C, Scuderi P, Terskikh A, Peitsch MC, Tschopp J
J Biol Chem. 1997
PubMed ID: 9228058
Tat protein induces self-perpetuating permissivity for productive HIV-1 infection.
Li CJ, Ueda Y, Shi B, Borodyansky L, Huang L, Li YZ, Pardee AB
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9223324
Interaction of Fas(Apo-1/CD95) with proteins implicated in the ubiquitination pathway.
Becker K, Schneider P, Hofmann K, Mattmann C, Tschopp J
FEBS Lett. 1997
PubMed ID: 9257699
Modulation of Bcl-2 protein by CD4 cross-linking: a possible mechanism for lymphocyte apoptosis in human immunodeficiency virus infection and for rescue of apoptosis by interleukin-2.
Hashimoto F, Oyaizu N, Kalyanaraman VS, Pahwa S
Blood. 1997
PubMed ID: 9226175
B cell genotype determines the fine specificity of autoantibody in lpr mice.
Kakkanaiah VN, Sobel ES, MacDonald GC, Cheek RL, Cohen PL, Eisenberg RA
J Immunol. 1997
PubMed ID: 9218626
Apoptosis induced by HIV-gp120 in a Th1 clone involves the generation of reactive oxygen intermediates downstream CD95 triggering.
Radrizzani M, Accornero P, Delia D, Kurrle R, Colombo MP
FEBS Lett. 1997
PubMed ID: 9247148
An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model.
Gong JH, Ratkay LG, Waterfield JD, Clark-Lewis I
J Exp Med. 1997
PubMed ID: 9207007
Daxx, a novel Fas-binding protein that activates JNK and apoptosis.
Yang X, Khosravi-Far R, Chang HY, Baltimore D
Cell. 1997
PubMed ID: 9215629
Casper is a FADD- and caspase-related inducer of apoptosis.
Shu HB, Halpin DR, Goeddel DV
Immunity. 1997
PubMed ID: 9208847
IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice.
Haas C, Ryffel B, Le Hir M
J Immunol. 1997
PubMed ID: 9164971
Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions.
Reap EA, Roof K, Maynor K, Borrero M, Booker J, Cohen PL
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9159145
Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis.
Zhang X, Brunner T, Carter L, Dutton RW, Rogers P, Bradley L, Sato T, Reed JC, Green D, Swain SL
J Exp Med. 1997
PubMed ID: 9151709
The Fas-deficient SCID mouse exhibits the development of T cells in the thymus.
Yasutomo K, Maeda K, Hisaeda H, Good RA, Kuroda Y, Himeno K
J Immunol. 1997
PubMed ID: 9144486
Expansion of an unusual population of Gr-1+CD3int cells in the lymph nodes and other peripheral organs of mice carrying the lpr gene.
Honda S, Takeda K, Narita J, Koya T, Kawamura T, Kuwano Y, Watanabe H, Arakawa M, Abo T
Cell Immunol. 1997
PubMed ID: 9178641
Tumor necrosis factor receptor p55 is essential for intrahepatic granuloma formation and hepatocellular apoptosis in a murine model of bacterium-induced fulminant hepatitis.
Tsuji H, Harada A, Mukaida N, Nakanuma Y, Bluethmann H, Kaneko S, Yamakawa K, Nakamura SI, Kobayashi KI, Matsushima K
Infect Immun. 1997
PubMed ID: 9125577
Identification of amino acid residues important for ligand binding to Fas.
Starling GC, Bajorath J, Emswiler J, Ledbetter JA, Aruffo A, Kiener PA
J Exp Med. 1997
PubMed ID: 9126929
Roles of interferon-gamma and interleukin-4 in murine lupus.
Peng SL, Moslehi J, Craft J
J Clin Invest. 1997
PubMed ID: 9109438
The receptor for the cytotoxic ligand TRAIL.
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM
Science. 1997
PubMed ID: 9082980
The molecular interaction of Fas and FAP-1. A tripeptide blocker of human Fas interaction with FAP-1 promotes Fas-induced apoptosis.
Yanagisawa J, Takahashi M, Kanki H, Yano-Yanagisawa H, Tazunoki T, Sawa E, Nishitoba T, Kamishohara M, Kobayashi E, Kataoka S, Sato T
J Biol Chem. 1997
PubMed ID: 9079683
Partial structure, chromosome localization, and expression of the mouse Icln gene.
Wickman K, Seldin MF, James MR, Gendler SJ, Clapham DE
Genomics. 1997
PubMed ID: 9073507
Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.
Vincenz C, Dixit VM
J Biol Chem. 1997
PubMed ID: 9045686
T cell-mediated elimination of B7.2 transgenic B cells.
Fournier S, Rathmell JC, Goodnow CC, Allison JP
Immunity. 1997
PubMed ID: 9075933
alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity.
Peng SL, McNiff JM, Madaio MP, Ma J, Owen MJ, Flavell RA, Hayday AC, Craft J
J Immunol. 1997
PubMed ID: 9036998
Clincal, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis.
Sneller MC, Wang J, Dale JK, Strober W, Middelton LA, Choi Y, Fleisher TA, Lim MS, Jaffe ES, Puck JM, Lenardo MJ, Straus SE
Blood. 1997
PubMed ID: 9028957
Apoptosis by death factor.
Nagata S
Cell. 1997
PubMed ID: 9039262
Androgen stimulation of lacrimal gland function in mouse models of Sjögren's syndrome.
Sullivan DA, Edwards JA
J Steroid Biochem Mol Biol. 1997
PubMed ID: 9191982
Enhancement of ectopic bone formation in mice with a deficit in Fas-mediated apoptosis.
Mori S, Nose M, Chiba M, Narita K, Kumagai M, Kosaka H, Teshima T
Pathol Int. 1997
PubMed ID: 9088029
Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis.
Bettinardi A, Brugnoni D, Quiròs-Roldan E, Malagoli A, La Grutta S, Correra A, Notarangelo LD
Blood. 1997
PubMed ID: 9028321
Differential susceptibility to HIV-GP120-sensitized apoptosis in CD4+ T-cell clones with different T-helper phenotypes: role of CD95/CD95L interactions.
Accornero P, Radrizzani M, Delia D, Gerosa F, Kurrle R, Colombo MP
Blood. 1997
PubMed ID: 9002959
ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha.
Künstle G, Leist M, Uhlig S, Revesz L, Feifel R, MacKenzie A, Wendel A
Immunol Lett. 1997
PubMed ID: 9093874
IL-1 beta convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms.
Smith DJ, McGuire MJ, Tocci MJ, Thiele DL
J Immunol. 1997
PubMed ID: 8977187
The role of the perforin and Fas pathways of cytotoxicity in skin graft rejection.
Selvaggi G, Ricordi C, Podack ER, Inverardi L
Transplantation. 1996
PubMed ID: 8990386
NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain.
Huang B, Eberstadt M, Olejniczak ET, Meadows RP, Fesik SW
Nature. 1996
PubMed ID: 8967952
Association of human fas (CD95) with a ubiquitin-conjugating enzyme (UBC-FAP).
Wright DA, Futcher B, Ghosh P, Geha RS
J Biol Chem. 1996
PubMed ID: 8940097
Homeostatic regulation of CD8+ T cells after antigen challenge in the absence of Fas (CD95).
Zimmermann C, Rawiel M, Blaser C, Kaufmann M, Pircher H
Eur J Immunol. 1996
PubMed ID: 8977284
Cross-linking of Fas by antibodies to a peculiar domain of gp120 V3 loop can enhance T cell apoptosis in HIV-1-infected patients.
Silvestris F, Nagata S, Cafforio P, Silvestris N, Dammacco F
J Exp Med. 1996
PubMed ID: 8976184
Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity.
Drappa J, Vaishnaw AK, Sullivan KE, Chu JL, Elkon KB
N Engl J Med. 1996
PubMed ID: 8929361
Functional expression of Fas (CD95) protein in autoimmune lpr mice.
Cui H, Ju ST, Sherr DH
Cell Immunol. 1996
PubMed ID: 8929452
Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin.
Okura T, Gong L, Kamitani T, Wada T, Okura I, Wei CF, Chang HM, Yeh ET
J Immunol. 1996
PubMed ID: 8906799
Lupus nephritis in the absence of renal major histocompatibility complex class I and class II molecules.
Mukherjee R, Zhang Z, Zhong R, Yin ZQ, Roopenian DC, Jevnikar AM
J Am Soc Nephrol. 1996
PubMed ID: 8959638
Arteritis in a novel congenic strain of mice derived from MRL/Lpr lupus mice: genetic dissociation from glomerulonephritis and limited autoantibody production.
Nose M, Nishimura M, Ito MR, Toh J, Shibata T, Sugisaki T
Am J Pathol. 1996
PubMed ID: 8909264
The effect of a selective estrogen receptor modulator on the progression of spontaneous autoimmune disease in MRL lpr/lpr mice.
Apelgren LD, Bailey DL, Fouts RL, Short L, Bryan N, Evans GF, Sandusky GE, Zuckerman SH, Glasebrook A, Bumol TF
Cell Immunol. 1996
PubMed ID: 8871601
Regulation of tumor necrosis factor-and Fas-mediated apoptotic cell death by a novel cDNA TR2L.
Cao H, Mattison J, Zhao Y, Joki N, Grasso M, Chang NS
Biochem Biophys Res Commun. 1996
PubMed ID: 8858135
Fas-independent apoptosis of photoreceptor cells in C3H mice.
Nambu H, Yuge K, Shikata N, Tsubura A, Matsuzawa A
Exp Anim. 1996
PubMed ID: 8902493
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.
Smith KG, Strasser A, Vaux DL
EMBO J. 1996
PubMed ID: 8895561
Role of macrophages in the development of arteritis in MRL strains of mice with a deficit in Fas-mediated apoptosis.
Taniguchi Y, Ito MR, Mori S, Yonehara S, Nose M
Clin Exp Immunol. 1996
PubMed ID: 8870694
Activation of Src-family tyrosine kinases during Fas-induced apoptosis.
Schlottmann KE, Gulbins E, Lau SM, Coggeshall KM
J Leukoc Biol. 1996
PubMed ID: 8864141
Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice.
Wang J, Koizumi T, Watanabe T
J Exp Med. 1996
PubMed ID: 9064343
A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice.
Peng SL, Robert ME, Hayday AC, Craft J
J Exp Med. 1996
PubMed ID: 9064331
Contribution of Fas ligand to cardiac allograft rejection.
Seino K, Kayagaki N, Bashuda H, Okumura K, Yagita H
Int Immunol. 1996
PubMed ID: 8921411
Marked depletion at the late pro-B cell stage in the bone marrow of lpr mice correlates with the development of lymphadenopathy but not autoimmunity.
Dautigny N, Chabre H, Garcia C, Ezine S
Eur J Immunol. 1996
PubMed ID: 8814251
Role of calmodulin in HIV-potentiated Fas-mediated apoptosis.
Pan Z, Radding W, Zhou T, Hunter E, Mountz J, McDonald JM
Am J Pathol. 1996
PubMed ID: 8780394
Fas system-mediated apoptosis suppresses lymphopoiesis.
Yasutomo K, Nagasawa H, Hisaeda H, Good RA, Kuroda Y, Himeno K
J Immunol. 1996
PubMed ID: 8757318
Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells.
Foote LC, Schneider TJ, Fischer GM, Wang JK, Rasmussen B, Campbell KA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein TL
J Immunol. 1996
PubMed ID: 8757305
Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha.
Edwards CK, Zhou T, Zhang J, Baker TJ, De M, Long RE, Borcherding DR, Bowlin TL, Bluethmann H, Mountz JD
J Immunol. 1996
PubMed ID: 8759766
Vascular lesions in mice with a deficit in Fas-mediated apoptosis and their transfer.
Nose M, Ito MR, Ono M, Terasaki S, Miyazawa M, Mori S
Int J Cardiol. 1996
PubMed ID: 9119511
Urtica dioica agglutinin, a V beta 8.3-specific superantigen, prevents the development of the systemic lupus erythematosus-like pathology of MRL lpr/lpr mice.
Musette P, Galelli A, Chabre H, Callard P, Peumans W, Truffa-Bachi P, Kourilsky P, Gachelin G
Eur J Immunol. 1996
PubMed ID: 8765010
An analysis of apoptosis in lymphoid organs and lupus disease in murine systemic lupus erythematosus (SLE).
Ravirajan CT, Sarraf CE, Anilkumar TV, Golding MC, Alison MR, Isenberg DA
Clin Exp Immunol. 1996
PubMed ID: 8706339
Swapping between Fas and granulocyte colony-stimulating factor receptor.
Takahashi T, Tanaka M, Ogasawara J, Suda T, Murakami H, Nagata S
J Biol Chem. 1996
PubMed ID: 8663376
CD28 costimulation prevents cell death during primary T cell activation.
Noel PJ, Boise LH, Green JM, Thompson CB
J Immunol. 1996
PubMed ID: 8752911
Down regulation of Bcl-2 is the first step on Fas-mediated apoptosis of male reproductive tract.
Suzuki A, Matsuzawa A, Iguchi T
Oncogene. 1996
PubMed ID: 8700551
Cytokine gene expression in the MRL/lpr model of lupus nephritis.
Lemay S, Mao C, Singh AK
Kidney Int. 1996
PubMed ID: 8807576
Existence of a small population of IL-2R beta hi TCRint cells in SCG and MRL-lpr/lpr mice which produce normal Fas mRNA and Fas molecules from the lpr gene.
Yamagiwa S, Kuwano Y, Hasegawa K, Sato K, Ohtsuka K, Iiai T, Tomiyama K, Watanabe H, Sugahara S, Seki S, Asakura H, Abo T
Eur J Immunol. 1996
PubMed ID: 8766540
Spontaneous autoimmune skin lesions of MRL/n mice: autoimmune disease-prone genetic background in relation to Fas-defect MRL/1pr mice.
Furukawa F, Kanauchi H, Wakita H, Tokura Y, Tachibana T, Horiguchi Y, Imamura S, Ozaki S, Takigawa M
J Invest Dermatol. 1996
PubMed ID: 8752846
Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes.
Rubio CF, Kench J, Russell DM, Yawger R, Nemazee D
J Immunol. 1996
PubMed ID: 8683157
Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses.
Ma J, Xu J, Madaio MP, Peng Q, Zhang J, Grewal IS, Flavell RA, Craft J
J Immunol. 1996
PubMed ID: 8683147
Restriction of the TCR repertoire inhibits the development of memory T cells and prevents autoimmunity in lpr mice.
Perkins DL, Listman JA, Marshak-Rothstein A, Kozlow W, Kelley VR, Finn PW, Rimm IJ
J Immunol. 1996
PubMed ID: 8648148
beta2-microglobulin dependence of the lupus-like autoimmune syndrome of MRL-lpr mice.
Christianson GJ, Blankenburg RL, Duffy TM, Panka D, Roths JB, Marshak-Rothstein A, Roopenian DC
J Immunol. 1996
PubMed ID: 8648144
An N-terminal domain shared by Fas/Apo-1 (CD95) soluble variants prevents cell death in vitro.
Papoff G, Cascino I, Eramo A, Starace G, Lynch DH, Ruberti G
J Immunol. 1996
PubMed ID: 8648105
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.
Boldin MP, Goncharov TM, Goltsev YV, Wallach D
Cell. 1996
PubMed ID: 8681376
Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide.
Brossart P, Bevan MJ
J Exp Med. 1996
PubMed ID: 8676065
Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect.
Su X, Zhou T, Yang PA, Wang Z, Mountz JD
J Immunol. 1996
PubMed ID: 8666788
Mechanism of the development of autoimmune dacryodenitis in the mouse model for primary Sjögren's syndrome.
Takahashi M, Mimura Y, Hamano H, Haneji N, Yanagi K, Hayashi Y
Cell Immunol. 1996
PubMed ID: 8660799
Murine lupus in the absence of alpha beta T cells.
Peng SL, Madaio MP, Hughes DP, Crispe IN, Owen MJ, Wen L, Hayday AC, Craft J
J Immunol. 1996
PubMed ID: 8621947
Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice.
Mieza MA, Itoh T, Cui JQ, Makino Y, Kawano T, Tsuchida K, Koike T, Shirai T, Yagita H, Matsuzawa A, Koseki H, Taniguchi M
J Immunol. 1996
PubMed ID: 8621946
Genomic organization and chromosomal mapping of the bovine Fas/APO-1 gene.
Yoo J, Stone RT, Kappes SM, Toldo SS, Fries R, Beattie CW
DNA Cell Biol. 1996
PubMed ID: 8924212
Decreased auditory function in the C3H/lpr autoimmune disease mouse.
Trune DR, Kempton JB, Mitchell C
Hear Res. 1996
PubMed ID: 8793508
Autoantibodies to the collagenous region of C1q occur in three strains of lupus-prone mice.
Hogarth MB, Norsworthy PJ, Allen PJ, Trinder PK, Loos M, Morley BJ, Walport MJ, Davies KA
Clin Exp Immunol. 1996
PubMed ID: 8625515
Detection of nucleosome-IgG immune complexes in ascites from mice transplanted with anti-DNA antibody-secreting hybridomas and in plasma from MRL-lpr/lpr mice.
Fournié GJ
Clin Exp Immunol. 1996
PubMed ID: 8625514
Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I.
Zhou T, Edwards CK, Yang P, Wang Z, Bluethmann H, Mountz JD
J Immunol. 1996
PubMed ID: 8609380
Agalactosyl IgG and beta-1,4-galactosyltransferase gene expression in rheumatoid arthritis patients and in the arthritis-prone MRL lpr/lpr mouse.
Jeddi PA, Bodman-Smith KB, Lund T, Lydyard PM, Mengle-Gaw L, Isenberg DA, Youinou P, Delves PJ
Immunology. 1996
PubMed ID: 8675223
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.
Byth KF, Conroy LA, Howlett S, Smith AJ, May J, Alexander DR, Holmes N
J Exp Med. 1996
PubMed ID: 8666928
The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice.
Huang FP, Feng GJ, Lindop G, Stott DI, Liew FY
J Exp Med. 1996
PubMed ID: 8666903
Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.
French LE, Hahne M, Viard I, Radlgruber G, Zanone R, Becker K, Müller C, Tschopp J
J Cell Biol. 1996
PubMed ID: 8609166
Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice.
Takahashi S, Fossati L, Iwamoto M, Merino R, Motta R, Kobayakawa T, Izui S
J Clin Invest. 1996
PubMed ID: 8601623
In vivo role of IL-10 and IL-12 during development of Sjögren's syndrome in MRL/lpr mice.
Yanagi K, Haneji N, Hamano H, Takahashi M, Higashiyama H, Hayashi Y
Cell Immunol. 1996
PubMed ID: 8640871
Inhibition of apoptosis and augmentation of lymphoproliferation in bcl-2 transgenic Fas/Fas ligand-defective mice.
Tamura A, Katsumata M, Greene MI, Yui K
Cell Immunol. 1996
PubMed ID: 8640868
A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT.
Atkinson EA, Ostergaard H, Kane K, Pinkoski MJ, Caputo A, Olszowy MW, Bleackley RC
J Biol Chem. 1996
PubMed ID: 8626376
Decreased Fas antigen receptor expression in testicular tumor cell lines derived from polyomavirus large T-antigen transgenic mice.
Lebel M, Bertrand R, Mes-Masson AM
Oncogene. 1996
PubMed ID: 8649805
Enhanced and accelerated lymphoproliferation in Fas-null mice.
Adachi M, Suematsu S, Suda T, Watanabe D, Fukuyama H, Ogasawara J, Tanaka T, Yoshida N, Nagata S
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8700897
Functional significance of the Fas molecule in naive lymphocytes.
Senju S, Negishi I, Motoyama N, Wang F, Nakayama K, Nakayama K, Lucas PJ, Hatakeyama S, Zhang Q, Yonehara S, Loh DY
Int Immunol. 1996
PubMed ID: 8671629
The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance.
Van Parijs L, Ibraghimov A, Abbas AK
Immunity. 1996
PubMed ID: 8624822
Abnormal complement-mediated immune clearance in MRL-lpr/+ heterozygote mice: dose-dependent effect of the Fas antigen mutation.
Meryhew NL, Tam PE, Seim JK, Messner RP
Clin Immunol Immunopathol. 1996
PubMed ID: 8605699
A recurrent clonotype in the spontaneous anti-IgG2a rheumatoid factor response of lpr/lpr mice.
Hande S, Jacobson BA, Manser T
J Immunol. 1996
PubMed ID: 8596037
Alterations in activity of protein tyrosine phosphatase SH-PTP1 in autoimmune MRL/mpj-lpr/lpr mice.
Matsuda A, Matsuzawa S, Nakamura K, Mizuno Y, Kikuchi K
J Biochem. 1996
PubMed ID: 8882726
B-lineage cell deficits in bone marrow of lpr/lpr mice.
Sundblad A, Coutinho A
Int Immunol. 1996
PubMed ID: 8671610
Cyclosporine therapy suppresses ocular and lacrimal gland disease in MRL/Mp-lpr/lpr mice.
Jabs DA, Lee B, Burek CL, Saboori AM, Prendergast RA
Invest Ophthalmol Vis Sci. 1996
PubMed ID: 8603842
Regulation of T-cell death genes: selective inhibition of FasL- but not Fas-mediated function.
Cui H, Sherr DH, el-Khatib M, Matsui K, Panka DJ, Marshak-Rothstein A, Ju ST
Cell Immunol. 1996
PubMed ID: 8603437
Both Sm and DNA are selecting antigens in the anti-Sm B cell response in autoimmune MRL/lpr mice.
Retter MW, Cohen PL, Eisenberg RA, Clarke SH
J Immunol. 1996
PubMed ID: 8558010
Molecular cloning and characterization of murine IL-12 genes.
Yoshimoto T, Kojima K, Funakoshi T, Endo Y, Fujita T, Nariuchi H
J Immunol. 1996
PubMed ID: 8557982
Apoptosis in adult mouse testis induced by experimental cryptorchidism.
Ohta Y, Nishikawa A, Fukazawa Y, Urushitani H, Matsuzawa A, Nishina Y, Iguchi T
Acta Anat (Basel). 1996
PubMed ID: 9226038
Soluble Fas/Apo-1 splicing variants and apoptosis.
Cascino I, Papoff G, Eramo A, Ruberti G
Front Biosci. 1996
PubMed ID: 9159204
Cytokine gene expression and autoantibody production in Sjögren's syndrome of MRL/lpr mice.
Hayashi Y, Haneji N, Hamano H
Autoimmunity. 1996
PubMed ID: 8915033
Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes.
Li T, Ramirez K, Palacios R
Cell Growth Differ. 1996
PubMed ID: 8788039
Gene transfer of macrophage growth factors into the kidney of lpr mice initiates renal injury.
Yokoyama H, Naito T, Dranoff G, Mulligan RC, Rubin-Kelley V
Contrib Nephrol. 1996
PubMed ID: 8744045
A new alternative splice variant of the mouse Fas antigen with a deletion in the N-terminal portion of the extracellular domain.
Nakajima T, Ichii S, Furuyama J, Tamaoki T, Hashimoto T
Life Sci. 1996
PubMed ID: 8632723
Phenotypic abnormalities of splenic and bone marrow B cells in lpr and gld mice.
Reap EA, Piecyk ML, Oliver A, Sobel ES, Waldschmidt T, Cohen PL, Eisenberg RA
Clin Immunol Immunopathol. 1996
PubMed ID: 8599880
Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis. Activation-induced death can occur without Fas receptor.
Tucek-Szabo CL, Andjelić S, Lacy E, Elkon KB, Nikolić-Zugić J
J Immunol. 1996
PubMed ID: 8598462
Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.
Cascino I, Papoff G, De Maria R, Testi R, Ruberti G
J Immunol. 1996
PubMed ID: 8598453
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis.
Strasser A, Harris AW, Huang DC, Krammer PH, Cory S
EMBO J. 1995
PubMed ID: 8557033
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Chu K, Niu X, Williams LT
Proc Natl Acad Sci U S A. 1995
PubMed ID: 8524870
FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen.
Smith KG, Nossal GJ, Tarlinton DM
Proc Natl Acad Sci U S A. 1995
PubMed ID: 8524817
cDNA sequence analysis and characterization of a cytokine-inducing monoclonal antibody derived from autoimmune MRL/MP-lpr/lpr mouse.
Kimura N, Yoshikawa H, Iwamoto M, Sakihama T, Akasu F, Izui S, Ueno A, Nakajima Y, Tasaka K
Hybridoma. 1995
PubMed ID: 8770638
Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization.
Matsuyama T, Hata R, Yamamoto Y, Tagaya M, Akita H, Uno H, Wanaka A, Furuyama J, Sugita M
Brain Res Mol Brain Res. 1995
PubMed ID: 8750874
Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells.
Watanabe D, Suda T, Nagata S
Int Immunol. 1995
PubMed ID: 8746564
Fas and FasL in the homeostatic regulation of immune responses.
Lynch DH, Ramsdell F, Alderson MR
Immunol Today. 1995
PubMed ID: 8579749
bcl-2 transgenic Lpr mice show profound enhancement of lymphadenopathy.
Reap EA, Felix NJ, Wolthusen PA, Kotzin BL, Cohen PL, Eisenberg RA
J Immunol. 1995
PubMed ID: 7594564
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.
Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME
EMBO J. 1995
PubMed ID: 8521815
Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock.
Mountz JD, Baker TJ, Borcherding DR, Bluethmann H, Zhou T, Edwards CK
J Immunol. 1995
PubMed ID: 7594485
Effect of cyclophosphamide on lymphokine production in MRL/lpr.Yaa mice.
Kamada H, Takaoka Y, Kitagaki K, Nagai H
Inflamm Res. 1995
PubMed ID: 8597884
A naturally occurring soluble isoform of murine Fas generated by alternative splicing.
Hughes DP, Crispe IN
J Exp Med. 1995
PubMed ID: 7595210
Prevention of adoptive transfer of murine Sjögren's syndrome into severe combined immunodeficient (SCID) mice by antibodies against intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1).
Hayashi Y, Haneji N, Yanagi K, Higashiyama H, Yagita H, Hamano H
Clin Exp Immunol. 1995
PubMed ID: 7586691
Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver.
Adachi M, Suematsu S, Kondo T, Ogasawara J, Tanaka T, Yoshida N, Nagata S
Nat Genet. 1995
PubMed ID: 7581453
Elucidation of the protein kinase C-dependent apoptosis pathway in distinct subsets of T lymphocytes in MRL-lpr/lpr mice.
Ohkusu K, Isobe K, Hidaka H, Nakashima I
Eur J Immunol. 1995
PubMed ID: 7489761
Fas receptor expression on B-lineage cells.
Mandik L, Nguyen KA, Erikson J
Eur J Immunol. 1995
PubMed ID: 7489756
Immunosuppressive treatment prevents behavioral deficit in autoimmune MRL-lpr mice.
Sakić B, Szechtman H, Denburg SD, Denburg JA
Physiol Behav. 1995
PubMed ID: 8559794
Expression and function of the murine CD95/FasR/APO-1 receptor in relation to B cell ontogeny.
Onel KB, Tucek-Szabo CL, Ashany D, Lacy E, Nikolic-Zugic J, Elkon KB
Eur J Immunol. 1995
PubMed ID: 7589095
Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice.
Jacobson BA, Panka DJ, Nguyen KA, Erikson J, Abbas AK, Marshak-Rothstein A
Immunity. 1995
PubMed ID: 7584141
Defective signal-transduction pathways in T-cells from autoimmune MRL-lpr/lpr mice are associated with increased polyamine concentrations.
Thomas TJ, Gunnia UB, Seibold JR, Thomas T
Biochem J. 1995
PubMed ID: 7575451
T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice.
Nakayama K, Nakayama K, Dustin LB, Loh DY
J Exp Med. 1995
PubMed ID: 7561683
Differential expression of human Fas mRNA species upon peripheral blood mononuclear cell activation.
Liu C, Cheng J, Mountz JD
Biochem J. 1995
PubMed ID: 7575433
Calorie restriction modulates lymphocyte subset phenotype and increases apoptosis in MRL/lpr mice.
Luan X, Zhao W, Chandrasekar B, Fernandes G
Immunol Lett. 1995
PubMed ID: 8747716
Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.
Kneitz B, Herrmann T, Yonehara S, Schimpl A
Eur J Immunol. 1995
PubMed ID: 7589128
Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells.
Koh DR, Ho A, Rahemtulla A, Fung-Leung WP, Griesser H, Mak TW
Eur J Immunol. 1995
PubMed ID: 7589126
Apoptotic death of lymphocytes in murine acquired immunodeficiency syndrome: involvement of Fas-Fas ligand interaction.
Kanagawa O, Vaupel BA, Korsmeyer SJ, Russell JH
Eur J Immunol. 1995
PubMed ID: 7589105
The cell proliferation-associated protein Ki-67 is a target of autoantibodies in the serum of MRL mice.
Bloch DB, Rabkina D, Bloch KD
Lab Invest. 1995
PubMed ID: 7564269
Cytotoxicity to endothelial cells by sera from aged MRL/lpr/lpr mice is associated with autoimmunity to cell surface heparan sulfate.
Dimitriu-Bona A, Matic M, Ding W, Yang CP, Fillit H
Clin Immunol Immunopathol. 1995
PubMed ID: 7554444
Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo.
Mogil RJ, Radvanyi L, Gonzalez-Quintial R, Miller R, Mills G, Theofilopoulos AN, Green DR
Int Immunol. 1995
PubMed ID: 7495753
Fas-mediated cytotoxicity. An immunoeffector or immunoregulatory pathway in T cell-mediated immune responses?
Larsen CP, Alexander DZ, Hendrix R, Ritchie SC, Pearson TC
Transplantation. 1995
PubMed ID: 7544034
Biased T cell receptor V beta gene usage during specific stages of the development of autoimmune sialadenitis in the MRL/lpr mouse model of Sjögren's syndrome.
Hayashi Y, Hamano H, Haneji N, Ishimaru N, Yanagi K
Arthritis Rheum. 1995
PubMed ID: 7639803
Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease.
Green LM, Lazarus JP, LaBue M, Shah MM
Endocrinology. 1995
PubMed ID: 7628400
Relative perforin- and Fas-mediated lysis in T1 and T2 CD8 effector populations.
Carter LL, Dutton RW
J Immunol. 1995
PubMed ID: 7543509
The accumulation of B220+ CD4- CD8- (DN) T cells in C3H-lpr/lpr mice is not accelerated by the stimulation of CD8+ T cells or B220+ DN T cells with staphylococcal enterotoxin B and occurs independently of V beta 8+ T cells.
Giese T, Davidson WF
Int Immunol. 1995
PubMed ID: 7495728
Fas bridging cell death and cytotoxicity: the reaper connection.
Golstein P, Marguet D, Depraetere V
Immunol Rev. 1995
PubMed ID: 7493759
Transcription stimulation of the Fas-encoding gene by nuclear factor for interleukin-6 expression upon influenza virus infection.
Wada N, Matsumura M, Ohba Y, Kobayashi N, Takizawa T, Nakanishi Y
J Biol Chem. 1995
PubMed ID: 7543095
Soluble Fas/APO-1 in tumor cells: a potential regulator of apoptosis?
Owen-Schaub LB, Angelo LS, Radinsky R, Ware CF, Gesner TG, Bartos DP
Cancer Lett. 1995
PubMed ID: 7542559
Increased levels of antibodies to heat shock proteins with increasing age in Mrl/Mp-lpr/lpr mice.
Faulds G, Conroy S, Madaio M, Isenberg D, Latchman D
Br J Rheumatol. 1995
PubMed ID: 7670777
CDR3 regions in the preimmune VH B cell repertoire of lpr mice.
Alarcón-Riquelme ME, Fernández C
Clin Exp Immunol. 1995
PubMed ID: 7621595
Age-dependent reduction of Bcl-2 expression in peripheral T cells of lpr and gld mutant mice.
Tamura A, Yui K
J Immunol. 1995
PubMed ID: 7602121
Prevention of age-related T cell apoptosis defect in CD2-fas-transgenic mice.
Zhou T, Edwards CK, Mountz JD
J Exp Med. 1995
PubMed ID: 7540646
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome.
Fisher GH, Rosenberg FJ, Straus SE, Dale JK, Middleton LA, Lin AY, Strober W, Lenardo MJ, Puck JM
Cell. 1995
PubMed ID: 7540117
Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in E mu L-MYC transgenic mice but not in animals infected with MoMuLV.
Zörnig M, Grzeschiczek A, Kowalski MB, Hartmann KU, Möröy T
Oncogene. 1995
PubMed ID: 7784089
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.
Westendorp MO, Frank R, Ochsenbauer C, Stricker K, Dhein J, Walczak H, Debatin KM, Krammer PH
Nature. 1995
PubMed ID: 7539892
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity.
Rieux-Laucat F, Le Deist F, Hivroz C, Roberts IA, Debatin KM, Fischer A, de Villartay JP
Science. 1995
PubMed ID: 7539157
Non-exclusive Fas control and age dependence of viral superantigen-induced clonal deletion in lupus-prone mice.
Papiernik M, Pontoux C, Golstein P
Eur J Immunol. 1995
PubMed ID: 7542196
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.
Stanger BZ, Leder P, Lee TH, Kim E, Seed B
Cell. 1995
PubMed ID: 7538908
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM
Cell. 1995
PubMed ID: 7538907
In CD8+ T cell-deficient lpr/lpr mice, CD4+B220+ and CD4+B220- T cells replace B220+ double-negative T cells as the predominant populations in enlarged lymph nodes.
Giese T, Davidson WF
J Immunol. 1995
PubMed ID: 7537297
Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1 beta, interleukin-1 and interferon-gamma mRNA in the lymph nodes of lupus-prone mice.
Prud'homme GJ, Kono DH, Theofilopoulos AN
Mol Immunol. 1995
PubMed ID: 7783752
Sequence analysis of the germ-line VH gene corresponding to a nephritogenic antibody in MRL/lpr lupus mice.
Ono M, Yamamoto T, Kyogoku M, Nose M
Clin Exp Immunol. 1995
PubMed ID: 7743668
Autoantibodies produced spontaneously by young 1pr mice carry transforming growth factor beta and suppress cytotoxic T lymphocyte responses.
Rowley DA, Becken ET, Stach RM
J Exp Med. 1995
PubMed ID: 7722461
B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice.
Roark JH, Kuntz CL, Nguyen KA, Mandik L, Cattermole M, Erikson J
J Immunol. 1995
PubMed ID: 7722301
Effect of human cord blood transfer on survival and disease activity in MRL-lpr/lpr mice.
Ende N, Czarneski J, Raveche E
Clin Immunol Immunopathol. 1995
PubMed ID: 7704978
Expression and function of mouse Fas antigen on immature and mature T cells.
Nishimura Y, Ishii A, Kobayashi Y, Yamasaki Y, Yonehara S
J Immunol. 1995
PubMed ID: 7536770
Homology between reaper and the cell death domains of Fas and TNFR1.
Golstein P, Marguet D, Depraetere V
Cell. 1995
PubMed ID: 7537635
FAP-1: a protein tyrosine phosphatase that associates with Fas.
Sato T, Irie S, Kitada S, Reed JC
Science. 1995
PubMed ID: 7536343
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.
Boldin MP, Varfolomeev EE, Pancer Z, Mett IL, Camonis JH, Wallach D
J Biol Chem. 1995
PubMed ID: 7536190
Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein.
Birkeland ML, Copeland NG, Gilbert DJ, Jenkins NA, Barclay AN
Eur J Immunol. 1995
PubMed ID: 7737295
Immunomodulation of autoimmunity in MRL/lpr mice with syngeneic bone marrow transplantation (SBMT).
Karussis DM, Vourka-Karussis U, Lehmann D, Abramsky O, Ben-Nun A, Slavin S
Clin Exp Immunol. 1995
PubMed ID: 7697909
Thymic microenvironmental abnormalities in MRL/MP-lpr/lpr, BXSB/MpJ Yaa and C3H HeJ-gld/gld mice.
Takeoka Y, Yoshida SH, Van de Water J, Boyd R, Suehiro S, Ansari AA, Gershwin ME
J Autoimmun. 1995
PubMed ID: 7612145
Combined effects of FK506 (tacrolimus) and cyclophosphamide on atypical B220+ T cells, cytokine gene expression and disease activity in MRL/MpJ-lpr/lpr mice.
Woo J, Wright TM, Lemster B, Borochovitz D, Nalesnik MA, Thomson AW
Clin Exp Immunol. 1995
PubMed ID: 7535208
Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing.
Cascino I, Fiucci G, Papoff G, Ruberti G
J Immunol. 1995
PubMed ID: 7533181
Unexpectedly high occurrence of catalytic antibodies in MRL/lpr and SJL mice immunized with a transition-state analog: is there a linkage to autoimmunity?
Tawfik DS, Chap R, Green BS, Sela M, Eshhar Z
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7892238
The Fas death factor.
Nagata S, Golstein P
Science. 1995
PubMed ID: 7533326
Iron status alters murine systemic lupus erythematosus.
Leiter LM, Reuhl KR, Racis SP, Sherman AR
J Nutr. 1995
PubMed ID: 7876923
Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus.
Roark JH, Kuntz CL, Nguyen KA, Caton AJ, Erikson J
J Exp Med. 1995
PubMed ID: 7532679
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.
Brunner T, Mogil RJ, LaFace D, Yoo NJ, Mahboubi A, Echeverri F, Martin SJ, Force WR, Lynch DH, Ware CF
Nature. 1995
PubMed ID: 7530336
Abnormal splenic and thymic IL-4 and TNF-alpha expression in MRL-lpr/lpr mice.
Tsai CY, Wu TH, Huang SF, Sun KH, Hsieh SC, Han SH, Yu HS, Yu CL
Scand J Immunol. 1995
PubMed ID: 7863262
In vitro and in vivo effects of pentoxifylline on macrophages and lymphocytes derived from autoimmune MRL-lpr/lpr mice.
Hecht M, Müller M, Lohmann-Matthes ML, Emmendörffer A
J Leukoc Biol. 1995
PubMed ID: 7852838
Expression of the B cell repertoire in lpr mice; abnormal expansion of a few VHJ558 germ-line genes.
Alarcón-Riquelme ME, Fernández C
Clin Exp Immunol. 1995
PubMed ID: 7851020
Spontaneous development of corneal crystalline deposits in MRL/Mp mice.
Verhagen C, Rowshani T, Willekens B, van Haeringen NJ
Invest Ophthalmol Vis Sci. 1995
PubMed ID: 7843914
The abnormal lpr double-negative T cell fails to proliferate in vivo.
Sobel ES, Kakkanaiah VN, Rapoport RG, Eisenberg RA, Cohen PL
Clin Immunol Immunopathol. 1995
PubMed ID: 7828372
Effect of long-term anti-CD4 or anti-CD8 treatment on the development of lpr CD4- CD8- double negative T cells and of the autoimmune syndrome in MRL-lpr/lpr mice.
Merino R, Fossati L, Iwamoto M, Takahashi S, Lemoine R, Ibnou-Zekri N, Pugliatti L, Merino J, Izui S
J Autoimmun. 1995
PubMed ID: 7734035
Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I.
Maldonado MA, Eisenberg RA, Roper E, Cohen PL, Kotzin BL
J Exp Med. 1995
PubMed ID: 7530760
Characterization of human Fas gene. Exon/intron organization and promoter region.
Cheng J, Liu C, Koopman WJ, Mountz JD
J Immunol. 1995
PubMed ID: 7529798
Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.
Avraham KB, Fletcher C, Overdier DG, Clevidence DE, Lai E, Costa RH, Jenkins NA, Copeland NG
Genomics. 1995
PubMed ID: 7789972
The site and stage of anti-DNA B-cell deletion.
Chen C, Nagy Z, Radic MZ, Hardy RR, Huszar D, Camper SA, Weigert M
Nature. 1995
PubMed ID: 7816141
Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice.
Reap EA, Leslie D, Abrahams M, Eisenberg RA, Cohen PL
J Immunol. 1995
PubMed ID: 7529292
Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.
Watanabe D, Suda T, Hashimoto H, Nagata S
EMBO J. 1995
PubMed ID: 7530197
A fas antigen receptor mutation allows development of toxic shock syndrome toxin-1-induced lethal shock in V beta 8.2 T-cell receptor transgenic mice.
Cullen CM, Bonventre PF, Heeg H, Bluethmann H, Mountz JD, Edwards CK
Pathobiology. 1995
PubMed ID: 8738468
Biphasic increase in circulating and renal TNF-alpha in MRL-lpr mice with differing regulatory mechanisms.
Yokoyama H, Kreft B, Kelley VR
Kidney Int. 1995
PubMed ID: 7731137
Increased responsiveness of B. cells in the murine MRL/lpr model of lupus nephritis to interleukin-1 beta.
Lebedeva TV, Singh AK
J Am Soc Nephrol. 1995
PubMed ID: 7703391
Fas and Fas ligand: lpr and gld mutations.
Nagata S, Suda T
Immunol Today. 1995
PubMed ID: 7533498
Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease-like wasting syndrome.
Chu JL, Ramos P, Rosendorff A, Nikolić-Zugić J, Lacy E, Matsuzawa A, Elkon KB
J Exp Med. 1995
PubMed ID: 7528774
Assignment of a locus for mouse lung tumor susceptibility to proximal chromosome 19.
Devereux TR, Wiseman RW, Kaplan N, Garren S, Foley JF, White CM, Anna C, Watson MA, Patel A, Jarchow S
Mamm Genome. 1994
PubMed ID: 7894154
Influence of the lpr environment on the lymph node cell phenotypes in C57BL/6 nubg and nulpr chimeras.
Tiberghien F, Ceredig R, Loor F
Immunology. 1994
PubMed ID: 7875735
Novel structural features of autoantibodies in murine lupus: a possible superantigen binding site?
Zack DJ, Wong AL, Weisbart RH
Immunol Cell Biol. 1994
PubMed ID: 7698822
Apoptosis, Fas and systemic autoimmunity: the MRL-lpr/lpr model.
Singer GG, Carrera AC, Marshak-Rothstein A, Martínez C, Abbas AK
Curr Opin Immunol. 1994
PubMed ID: 7536012
Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL lpr/lpr antibodies.
James JA, Mamula MJ, Harley JB
Clin Exp Immunol. 1994
PubMed ID: 7527740
Fas-mediated apoptosis in primary cultured mouse hepatocytes.
Ni R, Tomita Y, Matsuda K, Ichihara A, Ishimura K, Ogasawara J, Nagata S
Exp Cell Res. 1994
PubMed ID: 7526995
The mechanism of autoantibody production in an autoimmune MRL/lpr mouse.
Shan H, Shlomchik MJ, Marshak-Rothstein A, Pisetsky DS, Litwin S, Weigert MG
J Immunol. 1994
PubMed ID: 7525723
The effects of thymopentin on the development of SLE-like syndrome in the MRL/lpr-lpr mouse.
Nicoletti F, Zaccone P, Magro G, Barcellini W, Cavallaro V, Belli G, Cocuzza C, di Marco R, Meroni PL
Scand J Immunol. 1994
PubMed ID: 7973460
Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice.
Lowrance JH, O'Sullivan FX, Caver TE, Waegell W, Gresham HD
J Exp Med. 1994
PubMed ID: 7964455
Transfer of Sjögren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment.
Hayashi Y, Haneji N, Hamano H, Yanagi K
Eur J Immunol. 1994
PubMed ID: 7957574
Reduced galactosyltransferase mRNA levels are associated with the agalactosyl IgG found in arthritis-prone MRL-lpr/lpr strain mice.
Jeddi PA, Lund T, Bodman KB, Sumar N, Lydyard PM, Pouncey L, Heath LS, Kidd VJ, Delves PJ
Immunology. 1994
PubMed ID: 7835974
The expansion of a CD4+ T cell population bearing a distinctive beta chain in MRL lpr/lpr mice suggests a role for the fas protein in peripheral T cell selection.
Musette P, Pannetier C, Gachelin G, Kourilsky P
Eur J Immunol. 1994
PubMed ID: 7525303
In vivo CD4+ lymph node T cells from lpr mice generate CD4-CD8-B220+TCR-beta low cells.
Laouar Y, Ezine S
J Immunol. 1994
PubMed ID: 7523511
Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death.
Schulze-Osthoff K, Krammer PH, Dröge W
EMBO J. 1994
PubMed ID: 7523113
The role of B cells in lpr/lpr-induced autoimmunity.
Shlomchik MJ, Madaio MP, Ni D, Trounstein M, Huszar D
J Exp Med. 1994
PubMed ID: 7931063
Modulation of glomerular structure and function in murine lupus nephritis by methylprednisolone and cyclophosphamide.
Kiberd BA, Young ID
J Lab Clin Med. 1994
PubMed ID: 7930875
Evaluation of a model for post-partum arthritis and the role of oestrogen in prevention of MRL-lpr associated rheumatic conditions.
Ratkay LG, Zhang D, Tonzetich J, Levy JG, Waterfield JD
Clin Exp Immunol. 1994
PubMed ID: 7923884
Combined treatment of autoimmune MRL/MP-lpr/lpr mice with a herbal medicine, Ren-shen-yang-rong-tang (Japanese name: Ninjin-youei-to) plus suboptimal dosage of prednisolone.
Zhou NN, Nakai S, Kawakita T, Oka M, Nagasawa H, Himeno K, Nomoto K
Int J Immunopharmacol. 1994
PubMed ID: 7843856
Lpr and MRL background gene involvement in the control of adjuvant enhanced arthritis in MRL-lpr mice.
Ratkay LG, Tait B, Tonzetich J, Waterfield JD
J Autoimmun. 1994
PubMed ID: 7530961
Identification of Fas antigen associated with apoptotic cell death in murine ovary.
Guo MW, Mori E, Xu JP, Mori T
Biochem Biophys Res Commun. 1994
PubMed ID: 7524484
Fas antigen mRNA induction in postischemic murine brain.
Matsuyama T, Hata R, Tagaya M, Yamamoto Y, Nakajima T, Furuyama J, Wanaka A, Sugita M
Brain Res. 1994
PubMed ID: 7529644
Effects of the lpr mutation on elimination and inactivation of self-reactive B cells.
Rathmell JC, Goodnow CC
J Immunol. 1994
PubMed ID: 8077685
In vitro role of IL-1 in heightened IgG, anti-DNA, and nephritogenic idiotype production by B cells derived from the murine MRL/lpr lupus model.
Singh AK, Mao C, Lebedeva TV
Clin Immunol Immunopathol. 1994
PubMed ID: 8062453
MRL/lpr mice produce anti-Ro 52,000 MW antibodies: detection, analysis of specificity and site of production.
Wahren M, Skarstein K, Blange I, Pettersson I, Jonsson R
Immunology. 1994
PubMed ID: 7821973
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways.
Lowin B, Hahne M, Mattmann C, Tschopp J
Nature. 1994
PubMed ID: 7520535
Treatment with dextran-conjugated anti-IgD delays the development of autoimmunity in MRL-lpr/lpr mice.
Shirai A, Aoki I, Otani M, Mond JJ, Klinman DM
J Immunol. 1994
PubMed ID: 7519219
The use of transcutaneous photodynamic therapy in the prevention of adjuvant-enhanced arthritis in MRL/lpr mice.
Chowdhary RK, Ratkay LG, Neyndorff HC, Richter A, Obochi M, Waterfield JD, Levy JG
Clin Immunol Immunopathol. 1994
PubMed ID: 8050199
The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively.
Copeland NG, Jenkins NA, Harvey RP
Genomics. 1994
PubMed ID: 8001981
Interleukin-1 contributes to high level IgG production in the murine MRL/lpr lupus model.
Singh AK, Lebedeva TV
Immunol Invest. 1994
PubMed ID: 7959962
Pathogenesis of Sjögren's syndrome-like autoimmune lesions in MRL/lpr mice.
Hayashi Y, Haneji N, Hamano H
Pathol Int. 1994
PubMed ID: 7952145
The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice.
Singer GG, Abbas AK
Immunity. 1994
PubMed ID: 7533645
APO-I-mediated apoptosis in normal and malignant lymphocytes.
Dhein J, Behrmann I, Daniel PT, Debatin KM, Klas C, Möller P, Oehm A, Trauth BC, Walczak H, Krammer PH
Biochem Soc Trans. 1994
PubMed ID: 7529730
T cell specialization at environmental interfaces: T cells from the lung and the female genital tract of lpr and gld mice differ from their splenic and lymph node counterparts.
Ibraghimov AR, Lynch RG
Eur J Immunol. 1994
PubMed ID: 7519999
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.
Kägi D, Vignaux F, Ledermann B, Bürki K, Depraetere V, Nagata S, Hengartner H, Golstein P
Science. 1994
PubMed ID: 7518614
Genotype effects on the antioxidant enzymes activity and mRNA expression in liver and kidney tissues of autoimmune-prone MRL/MpJ-lpr/lpr mice.
Venkatraman JT, Chandrasekar B, Kim JD, Fernandes G
Biochim Biophys Acta. 1994
PubMed ID: 8025127
Lymphadenopathy induced by the cooperation between lprcg and gld genes is of lpr but not of gld phenotype.
Matsuzawa A, Katagiri T, Ogata Y, Kominami R, Kimura M
Eur J Immunol. 1994
PubMed ID: 8026532
The Yaa mutation induces the development of autoimmunity in mice heterozygous for the gld (generalized lymphadenopathy disease) mutation.
Rosenblatt N, Hartmann KU, Loor F
Cell Immunol. 1994
PubMed ID: 8025960
T-B collaboration for autoantibody production in lpr mice is cognate and MHC-restricted.
Sobel ES, Kakkanaiah VN, Kakkanaiah M, Cheek RL, Cohen PL, Eisenberg RA
J Immunol. 1994
PubMed ID: 8207226
The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage.
Bloom DD, St Clair EW, Pisetsky DS, Clarke SH
Eur J Immunol. 1994
PubMed ID: 8206093
Induction of graft versus host disease in SCID mice by MRL/lpr cell transfer.
Fraziano M, Montesano C, Sammarco I, di Cesare S, Caroleo MC, Mattei M, Cannata S, Poccia F, Bellavia A, Salerno A
Clin Immunol Immunopathol. 1994
PubMed ID: 8200130
Attenuation of lpr-graft-versus-host disease (GVHD) in MRL/lpr spleen cell-injected SCID mice by in vivo treatment with anti-V beta 8.1,2 monoclonal antibody.
Hosaka N, Nagata N, Miyashima S, Ikehara S
Clin Exp Immunol. 1994
PubMed ID: 8004820
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Hanabuchi S, Koyanagi M, Kawasaki A, Shinohara N, Matsuzawa A, Nishimura Y, Kobayashi Y, Yonehara S, Yagita H, Okumura K
Proc Natl Acad Sci U S A. 1994
PubMed ID: 7515183
A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice.
Gonzalo JA, Tarazona R, Schuurman HJ, Uytdehaag F, Wick G, Martínez C, Kroemer G
Clin Immunol Immunopathol. 1994
PubMed ID: 8181186
An isotype switched and somatically mutated rheumatoid factor clone isolated from a MRL-lpr/lpr mouse exhibits limited intraclonal affinity maturation.
Jacobson BA, Sharon J, Shan H, Shlomchik M, Weigert MG, Marshak-Rothstein A
J Immunol. 1994
PubMed ID: 8157964
Nephritogenic antibodies in MRL/lpr lupus mice: molecular characteristics in pathological and genetic aspects.
Itoh J, Takahashi S, Ono M, Yamamoto T, Nose M, Kyogoku M
Tohoku J Exp Med. 1994
PubMed ID: 7809912
T cells of staphylococcal enterotoxin B-tolerized autoimmune MRL-lpr/lpr mice require co-stimulation through the B7-CD28/CTLA-4 pathway for activation and can be reanergized in vivo by stimulation of the T cell receptor in the absence of this co-stimulato
Zhou T, Weaver C, Linsley PS, Mountz JD
Eur J Immunol. 1994
PubMed ID: 7514125
Decreased pro-inflammatory cytokines and increased antioxidant enzyme gene expression by omega-3 lipids in murine lupus nephritis.
Chandrasekar B, Fernandes G
Biochem Biophys Res Commun. 1994
PubMed ID: 8179624
Comparative influence of steroid hormones and immunosuppressive agents on autoimmune expression in lacrimal glands of a female mouse model of Sjögren's syndrome.
Sato EH, Sullivan DA
Invest Ophthalmol Vis Sci. 1994
PubMed ID: 8163351
Gene usage by an anti-U1 snRNP 70K monoclonal autoantibody derived from a lupus-prone mouse.
Pelsue S, Agris PF
J Autoimmun. 1994
PubMed ID: 8037837
Comparison of wasting syndrome in [MRL lpr/lpr-->MRL +/+] chimera and graft versus host disease in [B10.D2-->BALB/c] chimera and an attempt to transfer the wasting syndrome in [MRL lpr/lpr-->MRL +/+] to MRL +/+ mice.
Aihara M, Aihara Y, Nakajima H
J Dermatol Sci. 1994
PubMed ID: 7914743
Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice.
Jevnikar AM, Grusby MJ, Glimcher LH
J Exp Med. 1994
PubMed ID: 7908320
Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway?
Vignaux F, Golstein P
Eur J Immunol. 1994
PubMed ID: 7512034
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand.
Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S
Cell. 1994
PubMed ID: 7511063
Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule.
Cheng J, Zhou T, Liu C, Shapiro JP, Brauer MJ, Kiefer MC, Barr PJ, Mountz JD
Science. 1994
PubMed ID: 7510905
Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice.
Wu J, Zhou T, Zhang J, He J, Gause WC, Mountz JD
Proc Natl Acad Sci U S A. 1994
PubMed ID: 7510888
Long-term treatment with 5,5-diphenylhydantoin reduces lymphadenopathy and anti-ssDNA autoantibodies in C57BL/6-lpr/lpr mice.
Bloksma N, de Bakker JM, van Rooijen HJ, Punt P, Seinen W, Kammüller ME
Int J Immunopharmacol. 1994
PubMed ID: 8206693
Effects of early and late treatment with anti-CD4 monoclonal antibody on autoimmune disease in MRL/MP-lpr/lpr mice.
Jabs DA, Kuppers RC, Saboori AM, Burek CL, Enger C, Lee B, Prendergast RA
Cell Immunol. 1994
PubMed ID: 7907009
Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression.
Clements JL, Wolfe J, Cooper SM, Budd RC
Eur J Immunol. 1994
PubMed ID: 7510235
Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevents the accumulation of double negative T cells but not autoantibody production.
Giese T, Davidson WF
J Immunol. 1994
PubMed ID: 8120404
Functional distinctions between MRL-lpr and MRL-gld lymphocytes. Normal cells reverse the gld but not lpr immunoregulatory defect.
Ettinger R, Wang JK, Bossu P, Papas K, Sidman CL, Abbas AK, Marshak-Rothstein A
J Immunol. 1994
PubMed ID: 8120369
Cross-reactivity of IgG and IgM secreting B cells in normal and autoimmune mice.
Klinman DM
J Autoimmun. 1994
PubMed ID: 8198696
The tissue specific elevation in synthesis of the 90 kDa heat shock protein precedes the onset of disease in lupus prone MRL/lpr mice.
Faulds GB, Isenberg DA, Latchman DS
J Rheumatol. 1994
PubMed ID: 8182630
The role of B cell abnormalities in the systemic autoimmune syndromes of lpr and gld mice.
Eisenberg RA, Sobel ES, Reap EA, Halpern MD, Cohen PL
Semin Immunol. 1994
PubMed ID: 8167307
Parallels in T lymphocyte development between lpr and normal mice.
Budd RC, Van Houten N, Clements J, Mixter PF
Semin Immunol. 1994
PubMed ID: 8167306
Defective clonal deletion and anergy induction in TCR transgenic lpr/lpr mice.
Mountz JD, Bluethmann H, Zhou T, Wu J
Semin Immunol. 1994
PubMed ID: 8167304
Development of the T cell receptor repertoire in lpr mice.
Rozzo SJ, Eisenberg RA, Cohen PL, Kotzin BL
Semin Immunol. 1994
PubMed ID: 8167303
Introduction: lessons from the lpr mouse--T lymphocyte development.
Van Houten N, Budd RC
Semin Immunol. 1994
PubMed ID: 8167302
Rapamycin prolongs survival and arrests pathophysiologic changes in murine systemic lupus erythematosus.
Warner LM, Adams LM, Sehgal SN
Arthritis Rheum. 1994
PubMed ID: 8129783
Injections of complexes made of dsDNA and specific polyclonal antibodies extend MRL lpr mouse survival: a pilot study.
Lebrun P, Burny W, Cosyns JP, Saint-Remy JM
Lupus. 1994
PubMed ID: 8025586
Abnormal antigen receptor-initiated signal transduction in lpr T lymphocytes.
Altman A
Semin Immunol. 1994
PubMed ID: 7513195
MRL-lpr/lpr disease: theories meet Fas.
Steinberg AD
Semin Immunol. 1994
PubMed ID: 7513194
Mutations in the Fas antigen gene in lpr mice.
Nagata S
Semin Immunol. 1994
PubMed ID: 7513193
A variant mRNA species encoding a truncated form of Fas antigen in the rat liver.
Kimura K, Wakatsuki T, Yamamoto M
Biochem Biophys Res Commun. 1994
PubMed ID: 7507668
Immune complex-degradation ability of macrophages in MRL/Mp-lpr/lpr lupus mice and its regulation by cytokines.
Kanno H, Tachiwaki O, Nose M, Kyogoku M
Clin Exp Immunol. 1994
PubMed ID: 8287594
Composition of peritoneal macrophage membranes in autoimmune MRL lpr/lpr mice.
Hackshaw KV, Jackson NA, Shi Y
Life Sci. 1994
PubMed ID: 8072374
Differential B lymphocyte galactosyltransferase activity in the MRL mouse model of rheumatoid arthritis.
Axford JS, Alavi A, Bond A, Hay FC
Autoimmunity. 1994
PubMed ID: 8061165
Comparative efficacy of androgen analogues in suppressing lacrimal gland inflammation in a mouse model (MRL/lpr) of Sjögren's syndrome.
Rocha FJ, Sato EH, Sullivan BD, Sullivan DA
Adv Exp Med Biol. 1994
PubMed ID: 8030558
An autoimmune MRL/Mp-Ipr/Ipr mouse-derived monoclonal IgG antibody stimulates cytokine production in bone-marrow-derived cell line by cross-linking of a cell surface antigen and Fc receptor.
Sakihama T, Shirakura-Shibata Y, Akasu F, Iwamoto M, Izui S, Nakajima Y, Tasaka K
Autoimmunity. 1994
PubMed ID: 8025211
Pathogenesis of early nephritis in lupus prone mice with a genetic accelerating (lpr) factor.
Granholm NA, Cavallo T
Autoimmunity. 1994
PubMed ID: 7948604
Gld and lpr mice: single gene mutant models for failed self tolerance.
Bhandoola A, Yui K, Siegel RM, Zerva L, Greene MI
Int Rev Immunol. 1994
PubMed ID: 7930847
Autoimmunity in mice bearing lprcg: a novel mutant gene.
Kimura M, Matsuzawa A
Int Rev Immunol. 1994
PubMed ID: 7930845
T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.
Mountz JD, Zhou T, Long RE, Bluethmann H, Koopman WJ, Edwards CK
Arthritis Rheum. 1994
PubMed ID: 7907476
Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice.
Mountz JD, Zhou T, Bluethmann H, Wu J, Edwards CK
Int Rev Immunol. 1994
PubMed ID: 7528763
The genetic basis of autoimmune disease in MRL-lpr/lpr mice.
Shirai A, Klinman DM
Int Rev Immunol. 1994
PubMed ID: 7523550
In vivo cytokine gene expression in various T cell subsets of the autoimmune MRL/Mp-lpr/lpr mouse.
Mori K, Kobayashi S, Inobe M, Jia WY, Tamakoshi M, Miyazaki T, Uede T
Autoimmunity. 1994
PubMed ID: 7517710
Detection of polymorphisms within the Fas cDNA gene sequence by GC-clamp denaturing gradient gel electrophoresis.
Fiucci G, Ruberti G
Immunogenetics. 1994
PubMed ID: 7514572
Regulation of anti-Sm autoantibodies by the immunoglobulin heavy chain locus.
Halpern MD, Craven SY, Cohen PL, Eisenberg RA
J Immunol. 1993
PubMed ID: 8258724
Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis.
Bossu P, Singer GG, Andres P, Ettinger R, Marshak-Rothstein A, Abbas AK
J Immunol. 1993
PubMed ID: 7903104
Lack of connectivity between the induced and autoimmune repertoires of lpr/lpr mice.
Very DL, Panka DJ, Weissman D, Wysocki L, Manser T, Marshak-Rothstein A
Immunology. 1993
PubMed ID: 8307604
Mitogenic and cytogenetic evaluation of transforming growth factor-beta on murine preimplantation embryonic development in vitro.
Lim J, Bongso A, Ratnam S
Mol Reprod Dev. 1993
PubMed ID: 8305211
Double-negative T cells from MRL-lpr/lpr mice mediate cytolytic activity when triggered through adhesion molecules and constitutively express perforin gene.
Hammond DM, Nagarkatti PS, Goté LR, Seth A, Hassuneh MR, Nagarkatti M
J Exp Med. 1993
PubMed ID: 8245794
Murine complement-mediated immune clearance dysfunction is associated with the lymphoproliferative (lpr) gene.
Meryhew NL, Messner RP
Clin Immunol Immunopathol. 1993
PubMed ID: 8242904
Increases in protein phosphatase 2B activity in lymphoid tissues and T-lymphocytes of autoimmune MRL/MpJ-lpr/lpr mice.
Katagiri C, Kawamura T, Matsuzawa S, Mizuno Y, Matsumura S, Kikuchi K
J Biochem. 1993
PubMed ID: 8138545
Polyclonal B cell activation arises from different mechanisms in lupus-prone (NZB x NZW)F1 and MRL/MpJ-lpr/lpr mice.
Merino R, Iwamoto M, Fossati L, Izui S
J Immunol. 1993
PubMed ID: 7902378
Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice.
Möröy T, Grzeschiczek A, Petzold S, Hartmann KU
Proc Natl Acad Sci U S A. 1993
PubMed ID: 7504280
Complete Freund's adjuvant induces an earlier and more severe arthritis in MRL-lpr mice.
Ratkay LG, Zhang L, Tonzetich J, Waterfield JD
J Immunol. 1993
PubMed ID: 8409458
Induction of different types of glomerulonephritis by monoclonal antibodies derived from an MRL/lpr lupus mouse.
Itoh J, Nose M, Takahashi S, Ono M, Terasaki S, Kondoh E, Kyogoku M
Am J Pathol. 1993
PubMed ID: 8238259
The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.
Drappa J, Brot N, Elkon KB
Proc Natl Acad Sci U S A. 1993
PubMed ID: 7694292
Natural occurrence of Nuc in the sera of autoimmune-prone MRL/lpr mice.
Kanai Y, Miura K, Uehara T, Amagai M, Takeda O, Tanuma S, Kurosawa Y
Biochem Biophys Res Commun. 1993
PubMed ID: 8240349
Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis.
Mock BA, Krall MM, Dosik JK
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8105477
Expressions of cytokine genes during development of autoimmune sialadenitis in MRL/lpr mice.
Hamano H, Saito I, Haneji N, Mitsuhashi Y, Miyasaka N, Hayashi Y
Eur J Immunol. 1993
PubMed ID: 8405038
Selection of the T cell receptor repertoire in Lpr mice.
Herron LR, Eisenberg RA, Roper E, Kakkanaiah VN, Cohen PL, Kotzin BL
J Immunol. 1993
PubMed ID: 8376785
Dynamic associations of CD45 and Thy-1 on plasma membranes of C3H-gld/gld and C3H-lpr/lpr. I. Potential effects on proliferation and phosphatase activity.
Lynes MA, Tibbetts DJ, Swenson LM, Sidman CL
Cell Immunol. 1993
PubMed ID: 8104711
Serum glomerular binding activity is highly correlated with renal disease in MRL/lpr mice.
Bernstein KA, Bolshoun D, Lefkowith JB
Clin Exp Immunol. 1993
PubMed ID: 8370169
Allogenic MHC class II determinant(s) in MRL/Ipr autoimmune disease-prone mice. Unusual expression of an L1 transposable element creates molecular mimicry.
Bobé P, Benihoud K, Kiger N
J Immunol. 1993
PubMed ID: 7689616
Responses of mesangial cells of autoimmune mice to cytokines.
Liu YJ, Ooi BS
J Immunol. 1993
PubMed ID: 8345207
Effects of an aromatase inhibitor on thymus and kidney and on oestrogen receptors in female MRL/MP-lpr/lpr mice.
Greenstein BD, Dhaher YY, Bridges Ede F, Keser G, Khamashta MA, Etherington J, Greenstein AS, Coates PJ, Hall PA, Hughes GR
Lupus. 1993
PubMed ID: 8268969
The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn.
Chu JL, Drappa J, Parnassa A, Elkon KB
J Exp Med. 1993
PubMed ID: 7688033
Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene.
Wu J, Zhou T, He J, Mountz JD
J Exp Med. 1993
PubMed ID: 7688023
V gene analysis of anticardiolipin antibodies from MRL-lpr/lpr mice.
Kita Y, Sumida T, Ichikawa K, Maeda T, Yonaha F, Iwamoto I, Yoshida S, Koike T
J Immunol. 1993
PubMed ID: 8335914
Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse.
Foster MH, Sabbaga J, Line SR, Thompson KS, Barrett KJ, Madaio MP
J Immunol. 1993
PubMed ID: 8335911
Alterations in activities of protein phosphatases PP1 and PP2A in T and B lymphocytes of autoimmune MRL/MpJ-lpr/lpr mice.
Zhu T, Matsuzawa S, Mizuno Y, Kikuchi K
J Biochem. 1993
PubMed ID: 8407876
Treatment effect of a traditional Chinese medicine, ren-shen-yang-rong-tang (Japanese name: ninjin-youei-to), on autoimmune MRL/MP-lpr/lpr mice.
Nakai S, Kawakita T, Zhou NN, Matsuura K, Oka M, Nagasawa H, Saito Y, Suzuki A, Himeno K, Nomoto K
Int J Immunopharmacol. 1993
PubMed ID: 8375941
Immune-complex-mediated vasculitis increases coronary artery lipid accumulation in autoimmune-prone MRL mice.
Qiao JH, Castellani LW, Fishbein MC, Lusis AJ
Arterioscler Thromb. 1993
PubMed ID: 8499414
Splenic norepinephrine is decreased in MRL-lpr/lpr mice.
Breneman SM, Moynihan JA, Grota LJ, Felten DL, Felten SY
Brain Behav Immun. 1993
PubMed ID: 8347895
Antigen nonspecific effect of major histocompatibility complex haplotype on autoantibody levels in systemic lupus erythematosus-prone lpr mice.
Cohen PL, Creech E, Nakul-Aquaronne D, McDaniel R, Ackler S, Rapoport RG, Sobel ES, Eisenberg RA
J Clin Invest. 1993
PubMed ID: 7685774
The role of the interleukin-2 (IL-2)/IL-2 receptor pathway in MRL/lpr lymphadenopathy: the expanded CD4-8- T cell subset completely lacks functional IL-2 receptors.
Tanaka T, Nagasaka Y, Kitamura F, Kuida K, Suwa H, Miyasaka M
Eur J Immunol. 1993
PubMed ID: 7684688
Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide.
Russell JH, Rush B, Weaver C, Wang R
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8506280
Colony stimulating factor-1 in the induction of lupus nephritis.
Bloom RD, Florquin S, Singer GG, Brennan DC, Kelley VR
Kidney Int. 1993
PubMed ID: 8510378
Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal.
Suzuki H, Yasukawa K, Saito T, Narazaki M, Hasegawa A, Taga T, Kishimoto T
Eur J Immunol. 1993
PubMed ID: 8477802
An MRL/MpJ-lpr/lpr substrain with a limited expansion of lpr double-negative T cells and a reduced autoimmune syndrome.
Fossati L, Takahashi S, Merino R, Iwamoto M, Aubry JP, Nose M, Spach C, Motta R, Izui S
Int Immunol. 1993
PubMed ID: 8318455
Elevated production of interleukin 6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice.
Ohteki T, Okamoto S, Nakamura M, Nemoto E, Kumagai K
Immunol Lett. 1993
PubMed ID: 8102352
gld and lpr hematopoietic cell transfers: common and different serological features of the C57BL/6 chimeras.
Velin D, Goettelfinger P, Froidevaux S, Loor F
Cell Immunol. 1993
PubMed ID: 8098670
Distinctive expression of lprcg in the heterozygous state on different genetic backgrounds.
Ogata Y, Kimura M, Shimada K, Wakabayashi T, Onoda H, Katagiri T, Matsuzawa A
Cell Immunol. 1993
PubMed ID: 8495493
Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.
Zhou T, Bluethmann H, Eldridge J, Berry K, Mountz JD
J Immunol. 1993
PubMed ID: 7682246
Cognitive and neurologic deficits in the MRL/lpr mouse: a clinicopathologic study.
Hess DC, Taormina M, Thompson J, Sethi KD, Diamond B, Rao R, Chamberlain CR, Feldman DS
J Rheumatol. 1993
PubMed ID: 8496852
VH family utilization by IgG anti-DNA-secreting lymphocytes derived from autoimmune MRL-lpr/lpr mice.
Klinman DM, Dellacqua DK, Conover J, Huppi K
Arthritis Rheum. 1993
PubMed ID: 8457230
Nucleosome-specific antibody from an autoimmune MRL/Mp-lpr/lpr mouse.
Losman JA, Fasy TM, Novick KE, Massa M, Monestier M
Arthritis Rheum. 1993
PubMed ID: 8457229
Characterization of cross-reactive anti-DNA autoantibodies in murine lupus.
Banks TA, Babakhani F, Poulos BT, Duffy JJ, Kibler R
Immunol Invest. 1993
PubMed ID: 7685322
Spatial learning during the course of autoimmune disease in MRL mice.
Sakić B, Szechtman H, Denburg S, Carbotte R, Denburg JA
Behav Brain Res. 1993
PubMed ID: 8504012
Transcriptional repression and differential splicing of Fas mRNA by early transposon (ETn) insertion in autoimmune lpr mice.
Kobayashi S, Hirano T, Kakinuma M, Uede T
Biochem Biophys Res Commun. 1993
PubMed ID: 7681668
IgG3 cryoglobulins in autoimmune MRL-lpr/lpr mice: immunopathogenesis, therapeutic approaches and relevance to similar human diseases.
Izui S, Berney T, Shibata T, Fulpius T
Ann Rheum Dis. 1993
PubMed ID: 8481059
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice.
Adachi M, Watanabe-Fukunaga R, Nagata S
Proc Natl Acad Sci U S A. 1993
PubMed ID: 7680478
V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice.
Bloom DD, Davignon JL, Retter MW, Shlomchik MJ, Pisetsky DS, Cohen PL, Eisenberg RA, Clarke SH
J Immunol. 1993
PubMed ID: 8432995
Overlap of the anti-Sm and anti-DNA responses of MRL/Mp-lpr/lpr mice.
Bloom DD, Davignon JL, Cohen PL, Eisenberg RA, Clarke SH
J Immunol. 1993
PubMed ID: 8432994
Cloning and cDNA sequence analysis of nephritogenic monoclonal antibodies derived from an MRL/lpr lupus mouse.
Takahashi S, Itoh J, Nose M, Ono M, Yamamoto T, Kyogoku M
Mol Immunol. 1993
PubMed ID: 8429833
Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice.
Scott DE, Kisch WJ, Steinberg AD
J Immunol. 1993
PubMed ID: 8419493
Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.
Sobel ES, Yokoyama WM, Shevach EM, Eisenberg RA, Cohen PL
J Immunol. 1993
PubMed ID: 8380429
Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes.
Copeland NG, Gilbert DJ, Li K, Sawamura D, Giudice GJ, Chu ML, Jenkins NA, Uitto J
Genomics. 1993
PubMed ID: 8432531
Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice.
Reap EA, Sobel ES, Cohen PL, Eisenberg RA
J Exp Med. 1993
PubMed ID: 8418209
The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune sy
Takeda K, Dennert G
J Exp Med. 1993
PubMed ID: 8418197
A new allele at the lpr gene on mouse chromosome 19 expresses properties different from the original recessive mutation.
Watanabe T, Sakai Y, Hanai A, Masaki S, Ohno K, Miyawaki S, Matsuzawa A
Mamm Genome. 1993
PubMed ID: 8318739
Preventive action of carotenoids on the development of lymphadenopathy and proteinuria in MRL-lpr/lpr mice.
Tomita Y, Jyonouchi H, Engelman RW, Day NK, Good RA
Autoimmunity. 1993
PubMed ID: 8180322
Effect of a novel immunosuppressant, FK506, on spontaneous lupus nephritis in MRL/MpJ-lpr/lpr mice.
Entani C, Izumino K, Iida H, Fujita M, Asaka M, Takata M, Sasayama S
Nephron. 1993
PubMed ID: 7688103
Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
Watson ML, Rao JK, Gilkeson GS, Ruiz P, Eicher EM, Pisetsky DS, Matsuzawa A, Rochelle JM, Seldin MF
J Exp Med. 1992
PubMed ID: 1460423
Abnormal distribution of IL-6 receptor in aged MRL/lpr mice: elevated expression on B cells and absence on CD4+ cells.
Kobayashi I, Matsuda T, Saito T, Yasukawa K, Kikutani H, Hirano T, Taga T, Kishimoto T
Int Immunol. 1992
PubMed ID: 1363056
In situ hybridization reveals co-expression of embryonic and adult alpha globin genes in the earliest murine erythrocyte progenitors.
Leder A, Kuo A, Shen MM, Leder P
Development. 1992
PubMed ID: 1295728
Assignment of the human Fas antigen gene (Fas) to 10q24.1.
Inazawa J, Itoh N, Abe T, Nagata S
Genomics. 1992
PubMed ID: 1385309
Evidence for early onset, polyclonal activation of T cell subsets in mice homozygous for lpr.
Giese T, Davidson WF
J Immunol. 1992
PubMed ID: 1383337
Functional analyses of lpr gene in MRL/Mp-lpr/lpr mice. Role of lymph node stromal cells in lpr-lymphadenopathy.
Ohnishi-Inoue Y, Yasumizu R, Sugiura K, Nagata N, Fan H, Oyaizu N, Inaba M, Toki J, Ikehara S
Immunobiology. 1992
PubMed ID: 1286883
Dysregulated expression of cellular adhesion molecules in autoimmune-prone mice.
Wang W, Kobayashi S, Uede T
J Dermatol. 1992
PubMed ID: 1284074
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
Cohen PL, Eisenberg RA
Immunol Today. 1992
PubMed ID: 1282318
Murine models of autoimmune disease.
Mountz JD, Edwards CK
Curr Opin Rheumatol. 1992
PubMed ID: 1419496
Murine models of autoimmunity: T-cell and B-cell defects.
Mountz JD, Edwards CK
Curr Opin Rheumatol. 1992
PubMed ID: 1419495
MRL/MP-lpr/lpr mouse as a model of immune-induced sensorineural hearing loss.
Kusakari C, Hozawa K, Koike S, Kyogoku M, Takasaka T
Ann Otol Rhinol Laryngol Suppl. 1992
PubMed ID: 1416659
Effects of antioxidant vitamins C, E, and beta-carotene on immune functions in MRL/lpr mice and rats.
Weimann BJ, Weiser H
Ann N Y Acad Sci. 1992
PubMed ID: 1444056
Effects of the lpr/lpr mutation on T and B cell populations in the lamina propria of the small intestine, a mucosal effector site.
Aicher WK, Fujihashi K, Yamamoto M, Kiyono H, Pitts AM, McGhee JR
Int Immunol. 1992
PubMed ID: 1390438
The human APO-1 (APT) antigen maps to 10q23, a region that is syntenic with mouse chromosome 19.
Lichter P, Walczak H, Weitz S, Behrmann I, Krammer PH
Genomics. 1992
PubMed ID: 1385299
Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-V beta 8 antibodies.
de Alborán IM, Gonzalo JA, Kroemer G, Leonardo E, Marcos MA, Martínez C
Eur J Immunol. 1992
PubMed ID: 1386316
Evidence for the existence of two parallel differentiation pathways in the thymus of MRL lpr/lpr mice.
Matsuzaki Y, Pannetien C, Kanagawa O, Gachelin G, Nakauchi H
J Immunol. 1992
PubMed ID: 1378863
Functional characterisation of serum DNase I in MRL-lpr/lpr mice.
Peitsch MC, Hesterkamp T, Polzar B, Mannherz HG, Tschopp J
Biochem Biophys Res Commun. 1992
PubMed ID: 1497662
Nephritogenicity of the lprcg gene on the MRL background.
Kimura M, Ogata Y, Shimada K, Wakabayashi T, Onoda H, Katagiri T, Matsuzawa A
Immunology. 1992
PubMed ID: 1526655
Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.
Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC
J Biol Chem. 1992
PubMed ID: 1375228
Anti-CD4 monoclonal antibody therapy suppresses autoimmune disease in MRL/Mp-lpr/lpr mice.
Jabs DA, Burek CL, Hu Q, Kuppers RC, Lee B, Prendergast RA
Cell Immunol. 1992
PubMed ID: 1576659
Cochlear IgG in the C3H/lpr autoimmune strain mouse.
Wong ML, Young JS, Nilaver G, Morton JI, Trune DR
Hear Res. 1992
PubMed ID: 1629052
A crucial role of the thymus in induction by the lprcg gene of lymphadenopathy with autoimmunity in the mouse.
Matsuzawa A, Moriyama T, Ogata Y, Katagiri T, Kimura M
Immunology. 1992
PubMed ID: 1592441
Lacrimal and salivary gland inflammation in the C3H/Ipr autoimmune strain mouse: a potential mode for Sjögren's syndrome.
Johnson BC, Morton JI, Trune DR
Otolaryngol Head Neck Surg. 1992
PubMed ID: 1565490
Increase in potential activities of protein phosphatases PP1 and PP2A in lymphoid tissues of autoimmune MRL/MpJ-lpr/lpr mice.
Matsuzawa S, Tamura T, Mizuno Y, Kobayashi S, Okuyama H, Tsukitani Y, Uemura D, Kikuchi K
J Biochem. 1992
PubMed ID: 1319990
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis.
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S
Nature. 1992
PubMed ID: 1372394
Effects of deoxyspergualin on dipeptidyl peptidase-II and -IV in the spleen of BXSB mice and MRL/lpr mice during the development of the lupus erythematosus-like syndrome.
Hagihara M, Sekiguchi K, Fujiwara M, Aoyagi T, Takeuchi T, Nagatsu T
Biochem Pharmacol. 1992
PubMed ID: 1348619
Cell electrophoretic characterization of abnormally expanded lymphocytes in autoimmune lprcg, lpr, gld and Yaa mice, and of thymocyte subsets.
Shimizu M, Sekine K, Matsuzawa A, Iwaguchi T
Electrophoresis. 1992
PubMed ID: 1592043
A behavior profile of the MRL/Mp lpr/lpr mouse and its association with hydrocephalus.
Denenberg VH, Sherman GF, Rosen GD, Morrison L, Behan PO, Galaburda AM
Brain Behav Immun. 1992
PubMed ID: 1571603
Stria vascularis ultrastructural pathology in the C3H/lpr autoimmune strain mouse: a potential mechanism for immune-related hearing loss.
McMenomey SO, Russell NJ, Morton JI, Trune DR
Otolaryngol Head Neck Surg. 1992
PubMed ID: 1534162
The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen.
Watanabe-Fukunaga R, Brannan CI, Itoh N, Yonehara S, Copeland NG, Jenkins NA, Nagata S
J Immunol. 1992
PubMed ID: 1371136
Rheumatoid factors in mice bearing the lpr or gld mutation. Selective production of rheumatoid factor cryoglobulins in MRL/MPJ-lpr/lpr mice.
Shibata T, Berney T, Spertini F, Izui S
Clin Exp Immunol. 1992
PubMed ID: 1735182
Cryoglobulins and the immunopathological manifestations of autoimmune disease.
Denman AM
Clin Exp Immunol. 1992
PubMed ID: 1735180
Histological detection of c-myb and c-myc proto-oncogene expression in infiltrating cells in cutaneous lupus erythematosus-like lesions of MRL/l mice by in situ hybridization.
Kitajima T, Furukawa F, Kanauchi H, Imamura S, Ogawa K, Sugiyama T
Clin Immunol Immunopathol. 1992
PubMed ID: 1728975
Comparison of immunological effects of cholera toxin on autoimmune MRL/lpr and BXSB mice.
Zhou NN, Nakai S, Oka M, Nagasawa H, Himeno K
Microbiol Immunol. 1992
PubMed ID: 1406377
Autoimmune vasculitis in MRL/Mp-lpr/lpr mice: orthochromatic basophils participate in the development of delayed-type hypersensitivity angiitis.
Moyer CF, Jerome WG, Taylor R, Tulli H, Reinisch CL
Autoimmunity. 1992
PubMed ID: 1343764
Comparison of the N- and O-linked glycopeptides of lymph node cells from C57 BL/6 lpr/lpr and C57 BL/6 mice.
Di Virgilio S, Montecino-Rodriguez E, Rampelberg M, Schnek G, Hooghe R, Loor F
Autoimmunity. 1992
PubMed ID: 1299347
Tumor necrosis factor alpha in murine systemic lupus erythematosus disease models: implications for genetic predisposition and immune regulation.
Jacob CO, Hwang F, Lewis GD, Stall AM
Cytokine. 1991
PubMed ID: 1686413
Haematopoietic cell transfers between C57BL/6 mice differing at the lpr or gld locus.
Montecino-Rodriguez EM, Loor F
Immunology. 1991
PubMed ID: 1682243
Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids.
Gilkeson GS, Ruiz P, Pritchard AJ, Pisetsky DS
J Autoimmun. 1991
PubMed ID: 1777011
A molecular genetic linkage map of mouse chromosome 19, including the lpr, Ly-44, and Tdt genes.
Watanabe T, Sakai Y, Miyawaki S, Shimizu A, Koiwai O, Ohno K
Biochem Genet. 1991
PubMed ID: 1684099
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.
Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S
Cell. 1991
PubMed ID: 1713127
A multilocus linkage map of mouse chromosome 8.
Fletcher C, Norman DJ, Germond E, Heintz N
Genomics. 1991
PubMed ID: 2037298
New mutant mice of autoimmunity, CBA/KiJms-lprcg/lprcg, that could link the lpr and gld genes.
Kimura M, Ogata Y, Shimada K, Moriyama T, Matsuzawa A
Autoimmunity. 1991
PubMed ID: 1954317
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease.
Cohen PL, Eisenberg RA
Annu Rev Immunol. 1991
PubMed ID: 1910678
Different nature of the proliferation defects of GLD, LPR and MEV C57BL/6 mouse lymphoid cells.
Froidevaux S, Kuntz L, Velin D, Loor F
Autoimmunity. 1991
PubMed ID: 1756226
Treatment with IL2/vaccinia recombinant virus leads to serologic, histologic and phenotypic normalization of autoimmune MRL/lpr-lpr mice.
Gutierrez-Ramos JC, Andreu JL, Marcos MA, Vegazo IR, Martinez C
Autoimmunity. 1991
PubMed ID: 1742421
Liver is a possible site for the proliferation of abnormal CD3+4-8- double-negative lymphocytes in autoimmune MRL-lpr/lpr mice.
Ohteki T, Seki S, Abo T, Kumagai K
J Exp Med. 1990
PubMed ID: 2141631
Treatment of end stage MRL-1pr/lpr mouse lupus disease by a cyclophosphazene derived drug and by cyclosporin A.
In S, Dueymes M, Appolinaire-Pilipenko S, Sournies F, Labarre JF, Fournié GJ
J Clin Lab Immunol. 1990
PubMed ID: 1967044
Characterization and chromosomal mapping of a cDNA encoding tryptophan hydroxylase from a mouse mastocytoma cell line.
Stoll J, Kozak CA, Goldman D
Genomics. 1990
PubMed ID: 2110547
A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse.
Matsuzawa A, Moriyama T, Kaneko T, Tanaka M, Kimura M, Ikeda H, Katagiri T
J Exp Med. 1990
PubMed ID: 2406366
Thymic reticulum of autoimmune mice. II: Ultrastructural studies of mice with lupus-like syndrome (NZB, BXSB, MRL/l).
Nabarra B, Dardenne M, Bach JF
J Autoimmun. 1990
PubMed ID: 2331302
Serological and histological characterization of the new mutant strain of lpr mice, CBA/KlJms-lprcg/lprcg.
Kimura M, Mohri H, Shimada K, Wakabayashi T, Kanai Y, Matsuzawa A
Clin Exp Immunol. 1990
PubMed ID: 2302830
Detection of circulating immune complexes in MRL mice with different forms of glomerulonephritis.
Hewicker M, Kromschröder E, Trautwein G
Z Versuchstierkd. 1990
PubMed ID: 2238887
Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus.
Izui S
Autoimmunity. 1990
PubMed ID: 2129764
Reciprocal lymphoid cell homing studies using wild and LPR (lymphoproliferation) mutant C57BL mice.
Rodriguez EM, Hooghe RJ, Loor F
Autoimmunity. 1990
PubMed ID: 2129752
Differential effect of the autoimmune Yaa and lpr genes on the acceleration of lupus-like syndrome in MRL/MpJ mice.
Merino R, Shibata T, De Kossodo S, Izui S
Eur J Immunol. 1989
PubMed ID: 2599002
Analysis of granulomatous arteritis in MRL/Mp autoimmune disease mice bearing lymphoproliferative genes. The use of mouse genetics to dissociate the development of arteritis and glomerulonephritis.
Nose M, Nishimura M, Kyogoku M
Am J Pathol. 1989
PubMed ID: 2782373
Monoclonal antibody-mediated tumor regression by induction of apoptosis.
Trauth BC, Klas C, Peters AM, Matzku S, Möller P, Falk W, Debatin KM, Krammer PH
Science. 1989
PubMed ID: 2787530
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.
Yonehara S, Ishii A, Yonehara M
J Exp Med. 1989
PubMed ID: 2469768
Autoimmune disease and cochlear pathology in the C3H/lpr strain mouse.
Trune DR, Craven JP, Morton JI, Mitchell C
Hear Res. 1989
PubMed ID: 2708160
Abundant expression of type l K+ channels. A marker for lymphoproliferative diseases?
Grissmer S, Cahalan MD, Chandy KG
J Immunol. 1988
PubMed ID: 2456342
Molecular and functional properties of novel T cell subsets in C3H-gld/gld and nude mice. Implications for thymic and extrathymic maturation.
Yui K, Wadsworth S, Yellen A, Hashimoto Y, Kokai Y, Greene MI
Immunol Rev. 1988
PubMed ID: 3049314
Genetically determined murine models of immunodeficiency.
Shultz LD, Sidman CL
Annu Rev Immunol. 1987
PubMed ID: 3297105
Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.
Davidson WF, Dumont FJ, Bedigian HG, Fowlkes BJ, Morse HC
J Immunol. 1986
PubMed ID: 3009614
The influence of Yaa on anti-DNA responses of B6-lpr mice.
Pisetsky DS, Klatt C, Dawson D, Roths JB
Clin Immunol Immunopathol. 1985
PubMed ID: 3931946
High level expression of the plasma cell antigen PC.1 on the T-cell subset expanding in MRL/MpJ-lpr/lpr mice: detection with a xenogeneic monoclonal antibody and alloantisera.
Dumont FJ, Habbersett RC, Coker LZ, Nichols EA, Treffinger JA
Cell Immunol. 1985
PubMed ID: 2943419
Association of lpr gene with graft-vs.-host disease-like syndrome.
Theofilopoulos AN, Balderas RS, Gozes Y, Aguado MT, Hang LM, Morrow PR, Dixon FJ
J Exp Med. 1985
PubMed ID: 3891901
A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice.
Kelley VE, Ferretti A, Izui S, Strom TB
J Immunol. 1985
PubMed ID: 3918111
Abnormalities induced by the mutant gene, lpr. Patterns of disease and expression of murine leukemia viruses in SJL/J mice homozygous and heterozygous for lpr.
Morse HC, Roths JB, Davidson WF, Langdon WY, Fredrickson TN, Hartley JW
J Exp Med. 1985
PubMed ID: 2982991
Inhibition by restricted-calorie diet of lymphoproliferative disease and renal damage in MRL/lpr mice.
Fernandes G, Good RA
Proc Natl Acad Sci U S A. 1984
PubMed ID: 6592606
One-way occurrence of graft-versus-host disease in bone marrow chimaeras between congenic MRL mice.
Fujiwara M, Kariyone A
Immunology. 1984
PubMed ID: 6237981
Abrogation of murine lupus by the xid gene is associated with reduced responsiveness of B cells to T-cell-helper signals.
Fieser TM, Gershwin ME, Steinberg AD, Dixon FJ, Theofilopoulos AN
Cell Immunol. 1984
PubMed ID: 6235926
Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice.
Davidson WF, Roths JB, Holmes KL, Rudikoff E, Morse HC
J Immunol. 1984
PubMed ID: 6610701
Induction of various autoantibodies by mutant gene lpr in several strains of mice.
Izui S, Kelley VE, Masuda K, Yoshida H, Roths JB, Murphy ED
J Immunol. 1984
PubMed ID: 6609979
Spontaneous production of interleukin 3 by T lymphocytes from autoimmune MRL/MP-lpr/lpr mice.
Palacios R
Eur J Immunol. 1984
PubMed ID: 6430708
Chromosomal location of mouse gene 202 which is induced by interferons and specifies a 56.5 kD protein.
Samanta H, Pravtcheva DD, Ruddle FH, Lengyel P
J Interferon Res. 1984
PubMed ID: 6205102
Studies of congenic MRL-Ipr/Ipr.xid mice.
Steinberg EB, Santoro TJ, Chused TM, Smathers PA, Steinberg AD
J Immunol. 1983
PubMed ID: 6605990
A monoclonal antibody (100C5) to the Lyt-2-T cell population expanding in MRL/Mp-lpr/lpr mice detects a surface antigen normally expressed on Lyt-2+ cells and B cells.
Dumont FJ, Habbersett RC, Nichols EA, Treffinger JA, Tung AS
Eur J Immunol. 1983
PubMed ID: 6602708
Abnormalities induced by the mutant gene Ipr: expansion of a unique lymphocyte subset.
Morse HC, Davidson WF, Yetter RA, Murphy ED, Roths JB, Coffman RL
J Immunol. 1982
PubMed ID: 6815273
Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene.
Wofsy D, Murphy ED, Roths JB, Dauphinée MJ, Kipper SB, Talal N
J Exp Med. 1981
PubMed ID: 6975351
Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice.
Theofilopoulos AN, Balderas RS, Shawler DL, Lee S, Dixon FJ
J Exp Med. 1981
PubMed ID: 6972998
Mutations in mice that influence natural killer (NK) cell activity.
Clark EA, Shultz LD, Pollack SB
Immunogenetics. 1981
PubMed ID: 6971254
Inhibition of T cells proliferation and SLE-like syndrome of MRL/1 mice by whole body or total lymphoid irradiation.
Theofilopoulos AN, Balderas R, Shawler DL, Izui S, Kotzin BL, Strober S, Dixon FJ
J Immunol. 1980
PubMed ID: 6968773
Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice.
Theofilopoulos AN, Shawler DL, Eisenberg RA, Dixon FJ
J Exp Med. 1980
PubMed ID: 6444324
Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.
Theofilopoulos AN, Eisenberg RA, Bourdon M, Crowell JS, Dixon FJ
J Exp Med. 1979
PubMed ID: 762500
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.
Andrews BS, Eisenberg RA, Theofilopoulos AN, Izui S, Wilson CB, McConahey PJ, Murphy ED, Roths JB, Dixon FJ
J Exp Med. 1978
PubMed ID: 309911
The publication is not currently in our database, click on the link below to see it on pubmed.
PubMed ID:
The publication is not currently in our database, click on the link below to see it on pubmed.
PubMed ID:

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	355	14102	246097
EnsEMBL Gene(s)	ENSG00000026103 LRG_134	ENSMUSG00000024778	ENSRNOG00000019142
Unigene	Hs.244139	Mm.1626	Rn.162521
Homologene	FAS	Fas	Fas
OMIM	134637	N/A	N/A
GeneCards	FAS	N/A	N/A
Beta Cell Genomics	DT.100031255 DT.100031256 DT.100031258 DT.100689381 DT.100779824 DT.121212588 DT.121212598 DT.455842 DT.86821059 DT.95269153 DT.95308040	DT.102557629 DT.110476048 DT.110480886 DT.110481761 DT.110481834 DT.110485660 DT.110485701 DT.110499194 DT.110500525 DT.110503878 DT.110504845 DT.110517076 DT.110526394 DT.110531276 DT.110533477 DT.110543400 DT.110545406 DT.110553848 DT.110554000 DT.110561930 DT.110573200 DT.110588783 DT.110598213 DT.110601359 DT.110612364 DT.110635222 DT.110642590 DT.110666472 DT.110667859 DT.110669488 DT.110677964 DT.110684931 DT.110708594 DT.110709040 DT.110711625 DT.110722927 DT.110727374 DT.110731645 DT.110740826 DT.110747659 DT.110761202 DT.110763933 DT.110765034 DT.110766118 DT.110772338 DT.110774104 DT.110777720 DT.110792574 DT.110805099 DT.110806015 DT.110810806 DT.110812171 DT.110821025 DT.110847214 DT.110849062 DT.110873064 DT.110877702 DT.110879362 DT.110884712 DT.110885316 DT.110900350 DT.110906615 DT.110906679 DT.110913316 DT.110913754 DT.110916779 DT.110920894 DT.110931524 DT.110936465 DT.110948812 DT.110951152 DT.110955068 DT.110956995 DT.110961227 DT.110965917 DT.110966054 DT.110973130 DT.110976630 DT.110977345 DT.110978768 DT.110988883 DT.111002074 DT.111013277 DT.111015097 DT.111018158 DT.111019454 DT.111020471 DT.111023002 DT.111023719 DT.111024354 DT.111025632 DT.111025985 DT.111030705 DT.111030847 DT.111031632 DT.111034317 DT.111034871 DT.111038200 DT.111046504 DT.111060031 DT.485725 DT.50315363 DT.91304076 DT.97331773	N/A
Reactome	P25445	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	355	14102	246097

External resources from NIDDK Consortium Interconnectivity Network Top Help

Relevant resources:

View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
FAS	PDCD6	HPRD, IntAct, BioGRID	empirical	11606059
FAS	HIPK3	HPRD, IntAct, BioGRID	empirical	11034606
FAS	FEM1B	HPRD	empirical	10542291
FAS	FAF1	HPRD, MINT, BioGRID	empirical	9740801 8524870
FAS	C14orf1	HPRD, MINT, IntAct, BioGRID	empirical	16169070
FAS	APOA5	IntAct	empirical	21988832
FAS	CRMP1	HPRD, MINT, IntAct, BioGRID	empirical	16169070
FAS	DAXX	HPRD, IntAct, BioGRID	empirical	11193028 9215629 11483955 11003656 11495919
FAS	GADD45A	IntAct	empirical	21988832
FAS	EEF1A1	HPRD, MINT, IntAct, BioGRID	empirical	16169070
FAS	EGFR	HPRD	empirical	12586732
FAS	FAIM2	HPRD, BioGRID	empirical	10535980
FAS	FYN	HPRD, MINT	empirical	8626376 17159908
FAS	ANK3	HPRD	empirical	14694156
FAS	UBQLN1	IntAct	empirical	21988832
FAS	APAF1	HPRD	empirical	9267021
FAS	HNRNPC	IntAct	empirical	21988832
FAS	FAS	HPRD, IntAct, BioGRID	empirical	7536190 7538908 21382479
FAS	FASLG	HPRD, IntAct, BioGRID, Reactome	empirical	9228058 9126929 12887920 15659383 12753742 7530336
FAS	RHOA	BioGRID	empirical	15659383
FAS	LCK	HPRD, BioGRID	empirical	8864141
FAS	ARHGDIA	BioGRID	empirical	15659383
FAS	MAP3K5	IntAct	empirical	11495919
FAS	MET	HPRD	empirical	15911745
FAS	MSN	BioGRID	empirical	15659383
FAS	ATP6V0B	IntAct	empirical	21988832
FAS	RIF1	IntAct	empirical	16169070
FAS	PRKCA	HPRD	empirical	12586732
FAS	LRIF1	HPRD, MINT	empirical	16169070
FAS	MAPK8	BioGRID	empirical	15659383
FAS	PTPN6	HPRD	empirical	11786908
FAS	PTPN13	HPRD, IntAct	empirical	9079683 7536343 9835052 12724420 10918185
FAS	RAP1A	HPRD	empirical	15207703
FAS	BID	BioGRID	empirical	15659383
FAS	SRC	IntAct	empirical	18328427
FAS	BTK	HPRD	empirical	9751072
FAS	TNF	BioGRID	empirical	12753742
FAS	TNFRSF1A	BioGRID	empirical	15659383
FAS	UBC	BioGRID	empirical	21906983
FAS	UBA7	HPRD	empirical	8940097
FAS	UBE2I	HPRD, IntAct, BioGRID	empirical	9257699 11034606
FAS	SUMO1	HPRD, IntAct	empirical	8906799 11112409
FAS	EZR	HPRD, MINT, BioGRID	empirical	14676203 17159908 15659383
FAS	YES1	IntAct	empirical	18328427
FAS	BAG6	IntAct	empirical	21988832
FAS	CALM1	HPRD	empirical	14594800
FAS	TMX1	IntAct	empirical	21988832
FAS	CASP8	HPRD, MINT, IntAct, MIPS, BioGRID	empirical	11101867 17159907 17159908 16498403 18328427 18455983 21382479 21625644 17047155 11717445 12887920 10196099 15659383 9208847 9325248
FAS	CASP10	IntAct, BioGRID	empirical	11717445 15659383 9045686 9325248
FAS	FBF1	HPRD	empirical	10978533
FAS	TCAP	IntAct	empirical	21988832
FAS	CAV1	IntAct	empirical	21382479
FAS	TRADD	HPRD	empirical	9427646 8681376
FAS	RIPK1	HPRD, IntAct, BioGRID	empirical	7538908 9740801
FAS	TNFSF13	HPRD, BioGRID	empirical	10706119
FAS	FADD	HPRD, MINT, IntAct, MIPS, BioGRID	empirical	7538907 7536190 17159907 19118384 9325248 16498403 17159908 18328427 18455983 19001025 21382479 20935634 21625644 11717445 10196099 15659383 9082980 8967952 12107169
FAS	TNFRSF10B	BioGRID	empirical	15659383
FAS	CFLAR	BioGRID	empirical	9208847 9325248
FAS	KRIT1	BioGRID	empirical	14594800
FAS	MBD4	IntAct	empirical	21988832
FAS	CCND3	IntAct	empirical	21988832
FAS	BRE	BioGRID	empirical	15465831
FAS	CD47	HPRD	empirical	15917238
FAS	CASP8AP2	HPRD, BioGRID	empirical	10235259