HSPB1

Summary Top Help

Gene Description:

heat shock protein 1; heat shock 27kDa protein 1

Synonyms:

HSP27, Hsp25, Hsp27, HSPB1, HSP28, 27kDa, CMT2F, HS.76067, HMN2B, Hspb1, SRP27

Orthologs:

Human HSPB1 (protein-coding), Mouse Hspb1 (protein-coding), Rat Hspb1 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Rat: 1

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm30	Rat	chr12:8901318..29369703	20.47	318

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr7:75931861..75933614 (1.75 kb) View in Genome Browser

(Mouse) NCBIM37 - chr5:136363789..136365433 (1.64 kb) View in Genome Browser

(Rat) RGSC3.4 - chr12:21911205..21912784 (1.58 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for HSPB1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for HSPB1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 3

Biocarta: 3

Reactome: None available

NCI-Nature Pathway Interaction Database: 2

Gene Ontology: 40

Publications from PubMed Top Help

Type 1 Diabetes Publications: 2

Publications: 391

Absolute amounts and diffusibility of HSP72, HSP25, and αB-crystallin in fast- and slow-twitch skeletal muscle fibers of rat.
Larkins NT, Murphy RM, Lamb GD
Am J Physiol Cell Physiol. 2012
PubMed ID: 21975426
HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II.
Sanchez-Niño MD, Sanz AB, Sanchez-Lopez E, Ruiz-Ortega M, Benito-Martin A, Saleem MA, Mathieson PW, Mezzano S, Egido J, Ortiz A
Lab Invest. 2012
PubMed ID: 21931298
The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.
Fang Y, Mu J, Ma Y, Ma D, Fu D, Shen X
Mol Cell Biochem. 2012
PubMed ID: 21800051
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs).
Lopitz-Otsoa F, Rodriguez-Suarez E, Aillet F, Casado-Vela J, Lang V, Matthiesen R, Elortza F, Rodriguez MS
J Proteomics. 2011
PubMed ID: 22178446
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR
J Biol Chem. 2011
PubMed ID: 21987572
Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.
Bezzerri V, Borgatti M, Finotti A, Tamanini A, Gambari R, Cabrini G
J Immunol. 2011
PubMed ID: 22031759
Ubiquitination of heat shock protein 27 is mediated by its interaction with Smad ubiquitination regulatory factor 2 in A549 cells.
Sun Y, Zhou M, Fu D, Xu B, Fang T, Ma Y, Chen J, Zhang J
Exp Lung Res. 2011
PubMed ID: 21967197
Distension of the uterus induces HspB1 expression in rat uterine smooth muscle.
White BG, MacPhee DJ
Am J Physiol Regul Integr Comp Physiol. 2011
PubMed ID: 21900647
Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy.
Almeida-Souza L, Asselbergh B, d'Ydewalle C, Moonens K, Goethals S, de Winter V, Azmi A, Irobi J, Timmermans JP, Gevaert K, Remaut H, Van Den Bosch L, Timmerman V, Janssens S
J Neurosci. 2011
PubMed ID: 22031878
[Cellular expression of (R127W)HSPB1 and its co-localization with neurofilament light chain].
Zhang RX, Yang X, Zi XH, Li XB, Xia K, Liu T, Liu SM, Li L, Zhan YJ, Li L, Pan Q, Tang BS
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2011
PubMed ID: 21983720
Forced expression of heat shock protein 27 (Hsp27) reverses P-glycoprotein (ABCB1)-mediated drug efflux and MDR1 gene expression in Adriamycin-resistant human breast cancer cells.
Kanagasabai R, Krishnamurthy K, Druhan LJ, Ilangovan G
J Biol Chem. 2011
PubMed ID: 21784846
Decreased heat shock protein 27 expression and altered autophagy in human cells harboring A8344G mitochondrial DNA mutation.
Chen CY, Chen HF, Gi SJ, Chi TH, Cheng CK, Hsu CF, Ma YS, Wei YH, Liu CS, Hsieh M
Mitochondrion. 2011
PubMed ID: 21679777
Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers.
Gibert B, Hadchity E, Czekalla A, Aloy MT, Colas P, Rodriguez-Lafrasse C, Arrigo AP, Diaz-Latoud C
Oncogene. 2011
PubMed ID: 21423207
Three-dimensional structure of α-crystallin domain dimers of human small heat shock proteins HSPB1 and HSPB6.
Baranova EV, Weeks SD, Beelen S, Bukach OV, Gusev NB, Strelkov SV
J Mol Biol. 2011
PubMed ID: 21641913
Sequestration of toxic oligomers by HspB1 as a cytoprotective mechanism.
Ojha J, Masilamoni G, Dunlap D, Udoff RA, Cashikar AG
Mol Cell Biol. 2011
PubMed ID: 21670152
Phosphorylation status of heat shock protein 27 influences neurite growth in adult dorsal root ganglion sensory neurons in vitro.
Williams KL, Mearow KM
J Neurosci Res. 2011
PubMed ID: 21638305
Heat shock protein 27 and cyclophilin A associate with the pathogenesis of COPD.
Hu R, Ouyang Q, Dai A, Tan S, Xiao Z, Tang C
Respirology. 2011
PubMed ID: 21585617
Naloxone-precipitated morphine withdrawal evokes phosphorylation of heat shock protein 27 in rat heart through extracellular signal-regulated kinase.
Almela P, Martínez-Laorden E, Atucha NM, Milanés MV, Laorden ML
J Mol Cell Cardiol. 2011
PubMed ID: 21530534
Regulation by heat shock protein 27 of osteocalcin synthesis in osteoblasts.
Kato K, Adachi S, Matsushima-Nishiwaki R, Minamitani C, Natsume H, Katagiri Y, Hirose Y, Mizutani J, Tokuda H, Kozawa O, Otsuka T
Endocrinology. 2011
PubMed ID: 21427224
Serum antibody titers against heat shock protein 27 are associated with the severity of coronary artery disease.
Pourghadamyari H, Moohebati M, Parizadeh SM, Falsoleiman H, Dehghani M, Fazlinezhad A, Akhlaghi S, Tavallaie S, Sahebkar A, Paydar R, Ghayour-Mobarhan M, Ferns GA
Cell Stress Chaperones. 2011
PubMed ID: 21107776
Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.
Knapinska AM, Gratacós FM, Krause CD, Hernandez K, Jensen AG, Bradley JJ, Wu X, Pestka S, Brewer G
Mol Cell Biol. 2011
PubMed ID: 21245386
Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.
Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL
Science. 2011
PubMed ID: 21436445
Skeletal muscle tissue from the Goto-Kakizaki rat model of type-2 diabetes exhibits increased levels of the small heat shock protein Hsp27.
Mullen E, O'Reilly E, Ohlendieck K
Mol Med Report. 2011
PubMed ID: 21468556
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair.
Cosentino C, Grieco D, Costanzo V
EMBO J. 2011
PubMed ID: 21157431
Heat-shock protein expression in leukemia.
Sedlackova L, Spacek M, Holler E, Imryskova Z, Hromadnikova I
Tumour Biol. 2011
PubMed ID: 20694586
Effect of 3,4-methylenedioxyamphetamine on dendritic spine dynamics in rat neocortical neurons--involvement of heat shock protein 27.
Ruscher K, Fernandes E, Capela JP, Bastos Mde L, Wieloch T, Dirnagl U, Meisel A, Carvalho F
Brain Res. 2011
PubMed ID: 21075084
Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus.
Lively S, Brown IR
Brain Res. 2011
PubMed ID: 20971094
Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value.
Lomnytska MI, Becker S, Bodin I, Olsson A, Hellman K, Hellström AC, Mints M, Hellman U, Auer G, Andersson S
Br J Cancer. 2011
PubMed ID: 21119665
[The concentration of HSP 27 in tumour and adjacent distal mucosa in colorectal adenocarcinoma].
Strzelczyk JK, Krakowczyk Ł, Kasperczyk J, Strzelczyk J, Zalewska-Ziob M, Wiczkowski A
Przegl Lek. 2011
PubMed ID: 21961414
Unfolded protein response suppresses cisplatin-induced apoptosis via autophagy regulation in human hepatocellular carcinoma cells.
Chen R, Dai RY, Duan CY, Liu YP, Chen SK, Yan DM, Chen CN, Wei M, Li H
Folia Biol (Praha). 2011
PubMed ID: 21888831
HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.
Ke L, Meijering RA, Hoogstra-Berends F, Mackovicova K, Vos MJ, Van Gelder IC, Henning RH, Kampinga HH, Brundel BJ
PLoS One. 2011
PubMed ID: 21731611
Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation.
Shiryaev A, Dumitriu G, Moens U
J Mol Signal. 2011
PubMed ID: 21575178
Proteomic analysis reveals an elevated expression of heat shock protein 27 in preeclamptic placentas.
Shin JK, Baek JC, Kang MY, Park JK, Lee SA, Lee JH, Choi WS, Paik WY
Gynecol Obstet Invest. 2011
PubMed ID: 21335933
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
The hsp27kD heat shock protein and p38-MAPK signaling are required for regular epidermal differentiation.
Jonak C, Mildner M, Klosner G, Paulitschke V, Kunstfeld R, Pehamberger H, Tschachler E, Trautinger F
J Dermatol Sci. 2011
PubMed ID: 21081267
Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways.
Zhang H, Rajasekaran NS, Orosz A, Xiao X, Rechsteiner M, Benjamin IJ
J Mol Cell Cardiol. 2010
PubMed ID: 20863832
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.
Abisambra JF, Blair LJ, Hill SE, Jones JR, Kraft C, Rogers J, Koren J, Jinwal UK, Lawson L, Johnson AG, Wilcock D, O'Leary JC, Jansen-West K, Muschol M, Golde TE, Weeber EJ, Banko J, Dickey CA
J Neurosci. 2010
PubMed ID: 21084594
HspB1 (Hsp 27) expression and neuroprotection in the retina.
O'Reilly AM, Currie RW, Clarke DB
Mol Neurobiol. 2010
PubMed ID: 20514530
Identification of HSP27 as a potential tumor marker for colorectal cancer by the two-dimensional polyacrylamide gel electrophoresis.
Liu W, Ma Y, Huang L, Peng J, Zhang P, Zhang H, Chen J, Qin H
Mol Biol Rep. 2010
PubMed ID: 19842058
Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro.
Zhu Z, Xu X, Yu Y, Graham M, Prince ME, Carey TE, Sun D
Mol Pharm. 2010
PubMed ID: 20540527
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis.
Pozuelo-Rubio M
FEBS J. 2010
PubMed ID: 20618440
Effect of proteasome inhibition by MG-132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN-93 oligodendroglia cell line.
Bolhuis S, Richter-Landsberg C
J Neurochem. 2010
PubMed ID: 20089131
Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya.
Sawada K, Sakata-Haga H, Fukui Y
Brain Res. 2010
PubMed ID: 20462503
HSP27 controls GATA-1 protein level during erythroid cell differentiation.
de Thonel A, Vandekerckhove J, Lanneau D, Selvakumar S, Courtois G, Hazoume A, Brunet M, Maurel S, Hammann A, Ribeil JA, Zermati Y, Gabet AS, Boyes J, Solary E, Hermine O, Garrido C
Blood. 2010
PubMed ID: 20410505
Interaction of Hsp27 with native phosphorylase kinase under crowding conditions.
Chebotareva NA, Makeeva VF, Bazhina SG, Eronina TB, Gusev NB, Kurganov BI
Macromol Biosci. 2010
PubMed ID: 20491124
[Effect of the heat shock protein 27 on NOS expression of spinal cord anterior hornmotoneurons after brachial plexus avulsion].
Liu YR, Zhao GZ, Zhao YF, Wu JZ, Zhi Y
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010
PubMed ID: 20862803
Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane.
Razandi M, Pedram A, Levin ER
Mol Cell Biol. 2010
PubMed ID: 20439495
SUMOylation of the lens epithelium-derived growth factor/p75 attenuates its transcriptional activity on the heat shock protein 27 promoter.
Bueno MT, Garcia-Rivera JA, Kugelman JR, Morales E, Rosas-Acosta G, Llano M
J Mol Biol. 2010
PubMed ID: 20382164
Heat shock protein 25 expression and preferential Purkinje cell survival in the lurcher mutant mouse cerebellum.
Duffin CA, McFarland R, Sarna JR, Vogel MW, Armstrong CL
J Comp Neurol. 2010
PubMed ID: 20394049
Low-density lipoproteins induce heat shock protein 27 dephosphorylation, oligomerization, and subcellular relocalization in human vascular smooth muscle cells.
García-Arguinzonis M, Padró T, Lugano R, Llorente-Cortes V, Badimon L
Arterioscler Thromb Vasc Biol. 2010
PubMed ID: 20378850
The small heat shock protein 27 is a key regulator of CD8+ CD57+ lymphocyte survival.
Wood KL, Voss OH, Huang Q, Parihar A, Mehta N, Batra S, Doseff AI
J Immunol. 2010
PubMed ID: 20385876
Proteomic analysis reveals virus-specific Hsp25 modulation in cardiac myocytes.
Li L, Sevinsky JR, Rowland MD, Bundy JL, Stephenson JL, Sherry B
J Proteome Res. 2010
PubMed ID: 20196617
Ezrin, maspin, peroxiredoxin 2, and heat shock protein 27: potential targets of a streptococcal-induced autoimmune response in psoriasis.
Besgen P, Trommler P, Vollmer S, Prinz JC
J Immunol. 2010
PubMed ID: 20363977
miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway.
Yang F, Yin Y, Wang F, Wang Y, Zhang L, Tang Y, Sun S
Hepatology. 2010
PubMed ID: 20209605
Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy.
Almeida-Souza L, Goethals S, de Winter V, Dierick I, Gallardo R, Van Durme J, Irobi J, Gettemans J, Rousseau F, Schymkowitz J, Timmerman V, Janssens S
J Biol Chem. 2010
PubMed ID: 20178975
Functional promoter -1271G>C variant of HSPB1 predicts lung cancer risk and survival.
Guo H, Bai Y, Xu P, Hu Z, Liu L, Wang F, Jin G, Wang F, Deng Q, Tu Y, Feng M, Lu D, Shen H, Wu T
J Clin Oncol. 2010
PubMed ID: 20231684
Heat shock protein 27: induction by gastroduodenal reflux in vivo and augmentation of human esophageal mucosal cell growth in vitro.
Mauchley D, Meng X, Johnson T, Teitelbaum J, Babu A, Fullerton DA, Weyant MJ
J Thorac Cardiovasc Surg. 2010
PubMed ID: 20304146
Down-regulation of HSP27 sensitizes TRAIL-resistant tumor cell to TRAIL-induced apoptosis.
Zhuang H, Jiang W, Cheng W, Qian K, Dong W, Cao L, Huang Q, Li S, Dou F, Chiu JF, Fang XX, Lu M, Hua ZC
Lung Cancer. 2010
PubMed ID: 19540014
Age-related changes in HSP25 expression in basal ganglia and cortex of F344/BN rats.
Gupte AA, Morris JK, Zhang H, Bomhoff GL, Geiger PC, Stanford JA
Neurosci Lett. 2010
PubMed ID: 20144690
Examination of Association with Candidate Genes for Diabetic Nephropathy in a Mexican American Population.
Kim S, Abboud HE, Pahl MV, Tayek J, Snyder S, Tamkin J, Alcorn H, Ipp E, Nast CC, Elston RC, Iyengar SK, Adler SG
Clin J Am Soc Nephrol. 2010
PubMed ID: 20299368
Differential heat shock protein localization in chronic lymphocytic leukemia.
Dempsey NC, Leoni F, Ireland HE, Hoyle C, Williams JH
J Leukoc Biol. 2010
PubMed ID: 20007907
Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma.
Huang Q, Ye J, Huang Q, Chen W, Wang L, Lin W, Lin J, Lin X
Clin Chem Lab Med. 2010
PubMed ID: 19961396
Heat shock proteins: cell protection through protein triage.
Lanneau D, Wettstein G, Bonniaud P, Garrido C
ScientificWorldJournal. 2010
PubMed ID: 20694452
Regulation of lipopolysaccharide-induced inflammatory response by heat shock protein 27 in THP-1 cells.
Liu J, Hong S, Feng Z, Xin Y, Wang Q, Fu J, Zhang C, Li G, Luo L, Yin Z
Cell Immunol. 2010
PubMed ID: 20557877
Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy.
Rane MJ, Song Y, Jin S, Barati MT, Wu R, Kausar H, Tan Y, Wang Y, Zhou G, Klein JB, Li X, Cai L
Am J Physiol Renal Physiol. 2010
PubMed ID: 19726550
The small heat-shock protein Hsp27 undergoes ERK-dependent phosphorylation and redistribution to the cytoskeleton in response to dual leucine zipper-bearing kinase expression.
Robitaille H, Simard-Bisson C, Larouche D, Tanguay RM, Blouin R, Germain L
J Invest Dermatol. 2010
PubMed ID: 19675578
Proteomics of uveal melanomas suggests HSP-27 as a possible surrogate marker of chromosome 3 loss.
Coupland SE, Vorum H, Mandal N, Kalirai H, Honoré B, Urbak SF, Lake SL, Dopierala J, Damato B
Invest Ophthalmol Vis Sci. 2010
PubMed ID: 19643972
The signal transduction pathways of heat shock protein 27 phosphorylation in vascular smooth muscle cells.
Chen HF, Xie LD, Xu CS
Mol Cell Biochem. 2010
PubMed ID: 19609652
Heat shock protein 27 upregulation and phosphorylation in rat experimental autoimmune encephalomyelitis.
Kim H, Moon C, Ahn M, Byun J, Lee Y, Kim MD, Matsumoto Y, Koh CS, Shin T
Brain Res. 2009
PubMed ID: 19781527
Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells.
Hassan S, Biswas MH, Zhang C, Du C, Balaji KC
Oncogene. 2009
PubMed ID: 19767773
Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11.
Paduch R, Jakubowicz-Gil J, Kandefer-Szerszen M
J Biosci. 2009
PubMed ID: 20093746
The taming of small heat-shock proteins: crystallization of the alpha-crystallin domain from human Hsp27.
Baranova EV, Beelen S, Gusev NB, Strelkov SV
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009
PubMed ID: 20054128
Concentrations of antibodies against heat shock protein 27 in the sera of women with ovarian carcinoma.
Olejek A, Damasiewicz-Bodzek A, Bodzek P, Wielkoszyński T, Zamłyński J, Stołtny P, Skutil M
Int J Gynecol Cancer. 2009
PubMed ID: 19955928
[Expression of HSP70/HSP27 protein in residual lesion after NPC radiotherapy].
Wang R, Zhou G, Huang S, Feng X
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009
PubMed ID: 19952398
The small heat shock protein Hsp27 protects cortical neurons against the toxic effects of beta-amyloid peptide.
King M, Nafar F, Clarke J, Mearow K
J Neurosci Res. 2009
PubMed ID: 19530165
The small heat shock protein HSP25 protects astrocytes against stress induced by proteasomal inhibition.
Goldbaum O, Riedel M, Stahnke T, Richter-Landsberg C
Glia. 2009
PubMed ID: 19330846
Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead.
Stacchiotti A, Morandini F, Bettoni F, Schena I, Lavazza A, Grigolato PG, Apostoli P, Rezzani R, Aleo MF
Toxicology. 2009
PubMed ID: 19720107
Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection.
Friedman MJ, Li S, Li XJ
J Biol Chem. 2009
PubMed ID: 19656944
Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement.
Foster CS, Dodson AR, Ambroisine L, Fisher G, Møller H, Clark J, Attard G, De-Bono J, Scardino P, Reuter VE, Cooper CS, Berney DM, Cuzick J
Br J Cancer. 2009
PubMed ID: 19707199
Increased interaction between heat shock protein 27 and mitogen-activated protein kinase (p38 and extracellular signal-regulated kinase) in pre-eclamptic placentas.
Shin JK, Jeong YT, Jo HC, Kang MY, Chang IS, Baek JC, Park JK, Lee SA, Lee JH, Choi WS, Paik WY
J Obstet Gynaecol Res. 2009
PubMed ID: 20149037
Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.
Matafora V, D'Amato A, Mori S, Blasi F, Bachi A
Mol Cell Proteomics. 2009
PubMed ID: 19596686
Hsp27 inhibits IKKbeta-induced NF-kappaB activity and skeletal muscle atrophy.
Dodd SL, Hain B, Senf SM, Judge AR
FASEB J. 2009
PubMed ID: 19528257
Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity.
Brunet Simioni M, De Thonel A, Hammann A, Joly AL, Bossis G, Fourmaux E, Bouchot A, Landry J, Piechaczyk M, Garrido C
Oncogene. 2009
PubMed ID: 19597476
Modulation of HSP27 alters hypoxia-induced endothelial permeability and related signaling pathways.
Liu T, Guevara OE, Warburton RR, Hill NS, Gaestel M, Kayyali US
J Cell Physiol. 2009
PubMed ID: 19373869
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
HSPB7 is a SC35 speckle resident small heat shock protein.
Vos MJ, Kanon B, Kampinga HH
Biochim Biophys Acta. 2009
PubMed ID: 19464326
Heat shock protein 27 modification is increased in the human diabetic failing heart.
Gawlowski T, Stratmann B, Stork I, Engelbrecht B, Brodehl A, Niehaus K, Körfer R, Tschoepe D, Milting H
Horm Metab Res. 2009
PubMed ID: 19384818
Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27.
Garcia MC, Ray DM, Lackford B, Rubino M, Olden K, Roberts JD
J Biol Chem. 2009
PubMed ID: 19506078
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell. 2009
PubMed ID: 19615732
Large-scale proteomics analysis of the human kinome.
Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H
Mol Cell Proteomics. 2009
PubMed ID: 19369195
HSP25 affects the proliferation and differentiation of rat dental follicle cells.
Du Y, Gu HJ, Gong QM, Yang F, Ling JQ
Int J Oral Sci. 2009
PubMed ID: 20687299
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
siRNA knocks down Hsp27 and increases angiotensin II-induced phosphorylated NF-kappaB p65 levels in aortic smooth muscle cells.
Voegeli TS, Currie RW
Inflamm Res. 2009
PubMed ID: 19247578
Human heat shock protein 27 overexpressing mice are protected against hepatic ischemia and reperfusion injury.
Chen SW, Park SW, Kim M, Brown KM, D'Agati VD, Lee HT
Transplantation. 2009
PubMed ID: 19461484
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
MAPK mediates Hsp25 signaling in incisor development.
Lee MJ, Cai J, Kwak SW, Cho SW, Harada H, Jung HS
Histochem Cell Biol. 2009
PubMed ID: 19225803
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma.
Liao WC, Wu MS, Wang HP, Tien YW, Lin JT
Pancreas. 2009
PubMed ID: 19214136
PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5.
Kostenko S, Johannessen M, Moens U
Cell Signal. 2009
PubMed ID: 19166925
The level of Hsp27 in lymphocytes is negatively associated with a higher risk of lung cancer.
Wang F, Feng M, Xu P, Xiao H, Niu P, Yang X, Bai Y, Peng Y, Yao P, Tan H, Tanguay RM, Wu T
Cell Stress Chaperones. 2009
PubMed ID: 18800238
Induction of heat shock proteins 27 and 72 in retinal ganglion cells after acute pressure-induced ischaemia.
Windisch BK, LeVatte TL, Archibald ML, Chauhan BC
Clin Experiment Ophthalmol. 2009
PubMed ID: 19472539
The 27-kDa heat shock protein confers cytoprotective effects through a beta 2-adrenergic receptor agonist-initiated complex with beta-arrestin.
Rojanathammanee L, Harmon EB, Grisanti LA, Govitrapong P, Ebadi M, Grove BD, Miyagi M, Porter JE
Mol Pharmacol. 2009
PubMed ID: 19176359
Transduced HSP27 protein protects neuronal cell death by enhancing FALS-associated SOD1 mutant activity.
An JJ, Lee YP, Kim DW, Sohn EJ, Jeong HJ, Kang HW, Shin MJ, Kim MJ, Ahn EH, Jang SH, Kang JH, Kang TC, Won MH, Kwon OS, Cho SW, Lee KS, Park J, Eum WS, Choi SY
BMB Rep. 2009
PubMed ID: 19335999
Heterooligomeric complexes formed by human small heat shock proteins HspB1 (Hsp27) and HspB6 (Hsp20).
Bukach OV, Glukhova AE, Seit-Nebi AS, Gusev NB
Biochim Biophys Acta. 2009
PubMed ID: 19100870
Heat shock protein 27 protects lung epithelial cells from hyperoxia-induced apoptotic cell death.
Shao L, Perez RE, Gerthoffer WT, Truog WE, Xu D
Pediatr Res. 2009
PubMed ID: 19047919
Mice that overexpress human heat shock protein 27 have increased renal injury following ischemia reperfusion.
Chen SW, Kim M, Kim M, Song JH, Park SW, Wells D, Brown K, Belleroche J, D'Agati VD, Lee HT
Kidney Int. 2009
PubMed ID: 19020532
A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation.
Ikeda Y, Abe A, Ishida C, Takahashi K, Hayasaka K, Yamada M
J Neurol Sci. 2009
PubMed ID: 18952241
Elevated HSP27, HSP70 and HSP90 alpha in chronic obstructive pulmonary disease: markers for immune activation and tissue destruction.
Hacker S, Lambers C, Hoetzenecker K, Pollreisz A, Aigner C, Lichtenauer M, Mangold A, Niederpold T, Zimmermann M, Taghavi S, Klepetko W, Ankersmit HJ
Clin Lab. 2009
PubMed ID: 19350847
Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury.
Damarla M, Hasan E, Boueiz A, Le A, Pae HH, Montouchet C, Kolb T, Simms T, Myers A, Kayyali US, Gaestel M, Peng X, Reddy SP, Damico R, Hassoun PM
PLoS One. 2009
PubMed ID: 19240800
HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination.
Wu Y, Liu J, Zhang Z, Huang H, Shen J, Zhang S, Jiang Y, Luo L, Yin Z
Cell Signal. 2009
PubMed ID: 18950704
Protein expression profiling in esophageal adenocarcinoma patients indicates association of heat-shock protein 27 expression and chemotherapy response.
Langer R, Ott K, Specht K, Becker K, Lordick F, Burian M, Herrmann K, Schrattenholz A, Cahill MA, Schwaiger M, Hofler H, Wester HJ
Clin Cancer Res. 2008
PubMed ID: 19088045
Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.
Wang B, Malik R, Nigg EA, Körner R
Anal Chem. 2008
PubMed ID: 19007248
Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity.
Morris AM, Treweek TM, Aquilina JA, Carver JA, Walker MJ
FEBS J. 2008
PubMed ID: 19021764
Contribution of IL-6 to the Hsp72, Hsp25, and alphabeta-crystallin responses to inflammation and exercise training in mouse skeletal and cardiac muscle.
Huey KA, Meador BM
J Appl Physiol. 2008
PubMed ID: 18927263
Gene expression levels of heat shock proteins in the soleus and plantaris muscles of rats after hindlimb suspension or spaceflight.
Ishihara A, Fujino H, Nagatomo F, Takeda I, Ohira Y
J Physiol Sci. 2008
PubMed ID: 18845059
Heat shock proteins HSP70 and HSP27 in the cerebral spinal fluid of patients undergoing thoracic aneurysm repair correlate with the probability of postoperative paralysis.
Hecker JG, Sundram H, Zou S, Praestgaard A, Bavaria JE, Ramchandren S, McGarvey M
Cell Stress Chaperones. 2008
PubMed ID: 18418731
Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2.
Houlden H, Laura M, Wavrant-De Vrièze F, Blake J, Wood N, Reilly MM
Neurology. 2008
PubMed ID: 18832141
Heat shock protein 27, a novel regulator of 5-fluorouracil resistance in colon cancer.
Tsuruta M, Nishibori H, Hasegawa H, Ishii Y, Endo T, Kubota T, Kitajima M, Kitagawa Y
Oncol Rep. 2008
PubMed ID: 18949417
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
Comprehensive characterization of heat shock protein 27 phosphorylation in human endothelial cells stimulated by the microbial dithiole thiolutin.
Dai S, Jia Y, Wu SL, Isenberg JS, Ridnour LA, Bandle RW, Wink DA, Roberts DD, Karger BL
J Proteome Res. 2008
PubMed ID: 18720982
Heat shock protein 27 expression in the human testis showing normal and abnormal spermatogenesis.
Adly MA, Assaf HA, Hussein MR
Cell Biol Int. 2008
PubMed ID: 18692580
HSP27 is involved in the pathogenesis of kidney tubulointerstitial fibrosis.
Vidyasagar A, Reese S, Acun Z, Hullett D, Djamali A
Am J Physiol Renal Physiol. 2008
PubMed ID: 18596079
Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay.
Sinsimer KS, Gratacós FM, Knapinska AM, Lu J, Krause CD, Wierzbowski AV, Maher LR, Scrudato S, Rivera YM, Gupta S, Turrin DK, De La Cruz MP, Pestka S, Brewer G
Mol Cell Biol. 2008
PubMed ID: 18573886
Cyclic strain-induced HSP27 phosphorylation modulates actin filaments in airway smooth muscle cells.
Chaudhuri S, Smith PG
Am J Respir Cell Mol Biol. 2008
PubMed ID: 18390476
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
Mol Cell. 2008
PubMed ID: 18691976
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation.
Shi GX, Jin L, Andres DA
Mol Cell Biol. 2008
PubMed ID: 18541665
HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion.
Golembieski WA, Thomas SL, Schultz CR, Yunker CK, McClung HM, Lemke N, Cazacu S, Barker T, Sage EH, Brodie C, Rempel SA
Glia. 2008
PubMed ID: 18442089
Heat shock enhances NGF-induced neurite elongation which is not mediated by Hsp25 in PC12 cells.
Read DE, Reed Herbert K, Gorman AM
Brain Res. 2008
PubMed ID: 18561899
Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase.
Matsushima-Nishiwaki R, Takai S, Adachi S, Minamitani C, Yasuda E, Noda T, Kato K, Toyoda H, Kaneoka Y, Yamaguchi A, Kumada T, Kozawa O
J Biol Chem. 2008
PubMed ID: 18477563
Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase.
Evans IM, Britton G, Zachary IC
Cell Signal. 2008
PubMed ID: 18440775
Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation.
Chung KW, Kim SB, Cho SY, Hwang SJ, Park SW, Kang SH, Kim J, Yoo JH, Choi BO
Exp Mol Med. 2008
PubMed ID: 18587268
HSP27 regulates cell adhesion and invasion via modulation of focal adhesion kinase and MMP-2 expression.
Lee JW, Kwak HJ, Lee JJ, Kim YN, Lee JW, Park MJ, Jung SE, Hong SI, Lee JH, Lee JS
Eur J Cell Biol. 2008
PubMed ID: 18472181
Kinase activity, heat shock protein 27 phosphorylation, and lung epithelial cell glutathione.
Jackson RM, Garcia-Rojas R
Exp Lung Res. 2008
PubMed ID: 18465403
Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.
Forsman A, Rüetschi U, Ekholm J, Rymo L
J Proteome Res. 2008
PubMed ID: 18457437
Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization.
Quraishe S, Asuni A, Boelens WC, O'Connor V, Wyttenbach A
Neuroscience. 2008
PubMed ID: 18384969
Hsp27 regulates pro-inflammatory mediator release in keratinocytes by modulating NF-kappaB signaling.
Sur R, Lyte PA, Southall MD
J Invest Dermatol. 2008
PubMed ID: 18007587
Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain.
Villapol S, Acarin L, Faiz M, Castellano B, Gonzalez B
Neuroscience. 2008
PubMed ID: 18358624
[Correlation of high expression of HSP27 to multidrug resistance of leukemia cell line K562/VCR]
Zhang ZX, Wen FQ, Liu ZP, Cheng YD
Ai Zheng. 2008
PubMed ID: 18423118
Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27).
James PA, Rankin J, Talbot K
J Neurol Neurosurg Psychiatry. 2008
PubMed ID: 18344398
HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G2/M phase cell cycle arrest.
Venkatakrishnan CD, Dunsmore K, Wong H, Roy S, Sen CK, Wani A, Zweier JL, Ilangovan G
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 18263706
[Cytoskeletal proteins and heat shock proteins 27 under eccentric exercise of rats: effects of calcium L-type channel blockade]
Nemirovskaia TL, Kitina IuN, Zgelesniakova AV, Vikhliandtsev IM
Ross Fiziol Zh Im I M Sechenova. 2008
PubMed ID: 18507158
Expression of heat shock protein 27 with the transition from proliferation to differentiation of acinar precursor cell in regenerating submandibular gland of rats.
Takahashi-Horiuchi Y, Sugiyama K, Sakashita H, Amano O
Tohoku J Exp Med. 2008
PubMed ID: 18323692
Involvement of protein kinase C beta-extracellular signal-regulating kinase 1/2/p38 mitogen-activated protein kinase-heat shock protein 27 activation in hepatocellular carcinoma cell motility and invasion.
Guo K, Liu Y, Zhou H, Dai Z, Zhang J, Sun R, Chen J, Sun Q, Lu W, Kang X, Chen P
Cancer Sci. 2008
PubMed ID: 18167130
Control of estradiol-directed gene transactivation by an intracellular estrogen-binding protein and an estrogen response element-binding protein.
Chen H, Hewison M, Adams JS
Mol Endocrinol. 2008
PubMed ID: 18096692
Induction of p38MAPK and HSP27 phosphorylation in pemphigus patient skin.
Berkowitz P, Diaz LA, Hall RP, Rubenstein DS
J Invest Dermatol. 2008
PubMed ID: 17928890
Ginseng, the root of Panax ginseng C.A. Meyer, protects ethanol-induced gastric damages in rat through the induction of cytoprotective heat-shock protein 27.
Yeo M, Kim DK, Cho SW, Hong HD
Dig Dis Sci. 2008
PubMed ID: 17763949
The Role of heat shock protein 27 in extravillous trophoblast differentiation.
Matalon ST, Drucker L, Fishman A, Ornoy A, Lishner M
J Cell Biochem. 2008
PubMed ID: 17661346
Phosphoproteome of resting human platelets.
Zahedi RP, Lewandrowski U, Wiesner J, Wortelkamp S, Moebius J, Schütz C, Walter U, Gambaryan S, Sickmann A
J Proteome Res. 2008
PubMed ID: 18088087
Regulation of contractility by Hsp27 and Hic-5 in rat mesenteric small arteries.
Srinivasan R, Forman S, Quinlan RA, Ohanian J, Ohanian V
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 18083901
Proteomic identification of heat shock protein 27 as a differentiation and prognostic marker in neuroblastoma but not in Ewing's sarcoma.
Zanini C, Pulerà F, Carta F, Giribaldi G, Mandili G, Maule MM, Forni M, Turrini F
Virchows Arch. 2008
PubMed ID: 18066588
Responses of the 27-kDa heat shock protein to UVB irradiation in human epidermal melanocytes.
Shi B, Grahn JC, Reilly DA, Dizon TC, Isseroff RR
Exp Dermatol. 2008
PubMed ID: 18031542
PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells.
Yuan J, Rozengurt E
J Cell Biochem. 2008
PubMed ID: 17570131
P-cadherin and beta-catenin are useful prognostic markers in breast cancer patients; beta-catenin interacts with heat shock protein Hsp27.
Fanelli MA, Montt-Guevara M, Diblasi AM, Gago FE, Tello O, Cuello-Carrión FD, Callegari E, Bausero MA, Ciocca DR
Cell Stress Chaperones. 2008
PubMed ID: 18320359
Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.
Imami K, Sugiyama N, Kyono Y, Tomita M, Ishihama Y
Anal Sci. 2008
PubMed ID: 18187866
Contraction in human myometrium is associated with changes in small heat shock proteins.
MacIntyre DA, Tyson EK, Read M, Smith R, Yeo G, Kwek K, Chan EC
Endocrinology. 2008
PubMed ID: 17916631
Insulin-induced myocardial protection in isolated ischemic rat hearts requires p38 MAPK phosphorylation of Hsp27.
Li G, Ali IS, Currie RW
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 17906111
Heat shock protein 27 regulates oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via reactive oxygen species generation and Akt activation.
Liu L, Zhang XJ, Jiang SR, Ding ZN, Ding GX, Huang J, Cheng YL
Chin Med J (Engl). 2007
PubMed ID: 18167217
Hsp27 modulates p53 signaling and suppresses cellular senescence.
O'Callaghan-Sunol C, Gabai VL, Sherman MY
Cancer Res. 2007
PubMed ID: 18089808
Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1.
Zhai J, Lin H, Julien JP, Schlaepfer WW
Hum Mol Genet. 2007
PubMed ID: 17881652
The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model.
Kalesnykas G, Niittykoski M, Rantala J, Miettinen R, Salminen A, Kaarniranta K, Uusitalo H
Neuroscience. 2007
PubMed ID: 17993247
Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve.
Matt P, Fu Z, Carrel T, Huso DL, Dirnhofer S, Lefkovits I, Zerkowski HR, Van Eyk JE
J Mol Cell Cardiol. 2007
PubMed ID: 17949744
Protective effect of heat shock protein 27 using protein transduction domain-mediated delivery on ischemia/reperfusion heart injury.
Kwon JH, Kim JB, Lee KH, Kang SM, Chung N, Jang Y, Chung JH
Biochem Biophys Res Commun. 2007
PubMed ID: 17869218
Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity.
Zoubeidi A, Zardan A, Beraldi E, Fazli L, Sowery R, Rennie P, Nelson C, Gleave M
Cancer Res. 2007
PubMed ID: 17974989
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
Yu LR, Zhu Z, Chan KC, Issaq HJ, Dimitrov DS, Veenstra TD
J Proteome Res. 2007
PubMed ID: 17924679
Doxorubicin-induced cardiotoxicity: direct correlation of cardiac fibroblast and H9c2 cell survival and aconitase activity with heat shock protein 27.
Turakhia S, Venkatakrishnan CD, Dunsmore K, Wong H, Kuppusamy P, Zweier JL, Ilangovan G
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17873025
Regulation of stress-induced intracellular sorting and chaperone function of Hsp27 (HspB1) in mammalian cells.
Bryantsev AL, Kurchashova SY, Golyshev SA, Polyakov VY, Wunderink HF, Kanon B, Budagova KR, Kabakov AE, Kampinga HH
Biochem J. 2007
PubMed ID: 17650072
ATF5 promotes cell survival through transcriptional activation of Hsp27 in H9c2 cells.
Wang H, Lin G, Zhang Z
Cell Biol Int. 2007
PubMed ID: 17606386
Exogenous heat shock protein 27 uniquely blocks differentiation of monocytes to dendritic cells.
Laudanski K, De A, Miller-Graziano C
Eur J Immunol. 2007
PubMed ID: 17823891
H2O2 activation of HSP25/27 protects desmin from calpain proteolysis in rat ventricular myocytes.
Blunt BC, Creek AT, Henderson DC, Hofmann PA
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17513494
Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation.
Voss OH, Batra S, Kolattukudy SJ, Gonzalez-Mejia ME, Smith JB, Doseff AI
J Biol Chem. 2007
PubMed ID: 17597071
Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption.
Huang L, Min JN, Masters S, Mivechi NF, Moskophidis D
Genesis. 2007
PubMed ID: 17661394
Genetic variant in the HSPB1 promoter region impairs the HSP27 stress response.
Dierick I, Irobi J, Janssens S, Theuns J, Lemmens R, Jacobs A, Corsmit E, Hersmus N, Van Den Bosch L, Robberecht W, De Jonghe P, Van Broeckhoven C, Timmerman V
Hum Mutat. 2007
PubMed ID: 17623484
Maximal eccentric exercise induces a rapid accumulation of small heat shock proteins on myofibrils and a delayed HSP70 response in humans.
Paulsen G, Vissing K, Kalhovde JM, Ugelstad I, Bayer ML, Kadi F, Schjerling P, Hallén J, Raastad T
Am J Physiol Regul Integr Comp Physiol. 2007
PubMed ID: 17522120
Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma.
Takai S, Matsushima-Nishiwaki R, Tokuda H, Yasuda E, Toyoda H, Kaneoka Y, Yamaguchi A, Kumada T, Kozawa O
Life Sci. 2007
PubMed ID: 17673262
A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome.
Falsone SF, Gesslbauer B, Rek A, Kungl AJ
Proteomics. 2007
PubMed ID: 17623298
Inhibition of heat shock protein 27-mediated resistance to DNA damaging agents by a novel PKC delta-V5 heptapeptide.
Kim EH, Lee HJ, Lee DH, Bae S, Soh JW, Jeoung D, Kim J, Cho CK, Lee YJ, Lee YS
Cancer Res. 2007
PubMed ID: 17616692
Role(s) of nucleoli and phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass.
Kawano F, Matsuoka Y, Oke Y, Higo Y, Terada M, Wang XD, Nakai N, Fukuda H, Imajoh-Ohmi S, Ohira Y
Am J Physiol Cell Physiol. 2007
PubMed ID: 17182729
AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation.
O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C
J Biol Chem. 2007
PubMed ID: 17439945
Modulation of HSP25 and TNF-alpha during the early stages of functional overload of a rat slow and fast muscle.
Huey KA, McCall GE, Zhong H, Roy RR
J Appl Physiol. 2007
PubMed ID: 17379754
Plasminogen and angiostatin interact with heat shock proteins.
Dudani AK, Mehic J, Martyres A
Mol Cell Biochem. 2007
PubMed ID: 17206383
The interaction and cellular localization of HSP27 and ERbeta are modulated by 17beta-estradiol and HSP27 phosphorylation.
Al-Madhoun AS, Chen YX, Haidari L, Rayner K, Gerthoffer W, McBride H, O'Brien ER
Mol Cell Endocrinol. 2007
PubMed ID: 17350752
HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells.
Dall'Era MA, Oudes A, Martin DB, Liu AY
Prostate. 2007
PubMed ID: 17342744
Anthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation.
During RL, Gibson BG, Li W, Bishai EA, Sidhu GS, Landry J, Southwick FS
EMBO J. 2007
PubMed ID: 17446863
Anti-vpr activities of heat shock protein 27.
Liang D, Benko Z, Agbottah E, Bukrinsky M, Zhao RY
Mol Med. 2007
PubMed ID: 17622316
Photodynamic therapy resistant human colon carcinoma HT29 cells show cross-resistance to UVA but not UVC light.
Zacal N, Rainbow AJ
Photochem Photobiol. 2007
PubMed ID: 17576382
Markers of oxidative stress in the skeletal muscle of patients on haemodialysis.
Crowe AV, McArdle A, McArdle F, Pattwell DM, Bell GM, Kemp GJ, Bone JM, Griffiths RD, Jackson MJ
Nephrol Dial Transplant. 2007
PubMed ID: 17213227
Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling.
Alford KA, Glennie S, Turrell BR, Rawlinson L, Saklatvala J, Dean JL
J Biol Chem. 2007
PubMed ID: 17202147
A new method of purification of proteasome substrates reveals polyubiquitination of 20 S proteasome subunits.
Ventadour S, Jarzaguet M, Wing SS, Chambon C, Combaret L, Béchet D, Attaix D, Taillandier D
J Biol Chem. 2007
PubMed ID: 17189251
Heat shock protein 27 regulates neutrophil chemotaxis and exocytosis through two independent mechanisms.
Jog NR, Jala VR, Ward RA, Rane MJ, Haribabu B, McLeish KR
J Immunol. 2007
PubMed ID: 17277149
Comparative proteomic analysis reveals differential expression of Hsp25 following the directed differentiation of mouse embryonic stem cells.
Battersby A, Jones RD, Lilley KS, McFarlane RJ, Braig HR, Allen ND, Wakeman JA
Biochim Biophys Acta. 2007
PubMed ID: 17030443
Mobile phone base station-emitted radiation does not induce phosphorylation of Hsp27.
Hirose H, Sakuma N, Kaji N, Nakayama K, Inoue K, Sekijima M, Nojima T, Miyakoshi J
Bioelectromagnetics. 2007
PubMed ID: 17004241
Large-scale phosphorylation analysis of mouse liver.
Villén J, Beausoleil SA, Gerber SA, Gygi SP
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17242355
PRAK is essential for ras-induced senescence and tumor suppression.
Sun P, Yoshizuka N, New L, Moser BA, Li Y, Liao R, Xie C, Chen J, Deng Q, Yamout M, Dong MQ, Frangou CG, Yates JR, Wright PE, Han J
Cell. 2007
PubMed ID: 17254968
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Koch HB, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates JR, Menssen A, Hermeking H
Cell Cycle. 2007
PubMed ID: 17314511
Identification of differential proteins in nasopharyngeal carcinoma cells with p53 silence by proteome analysis.
Sun Y, Yi H, Zhang PF, Li MY, Li C, Li F, Peng F, Feng XP, Yang YX, Yang F, Xiao ZQ, Chen ZC
FEBS Lett. 2007
PubMed ID: 17184779
HSF2 binds to the Hsp90, Hsp27, and c-Fos promoters constitutively and modulates their expression.
Wilkerson DC, Skaggs HS, Sarge KD
Cell Stress Chaperones. 2007
PubMed ID: 17915561
Neuronal expression of constitutive heat shock proteins: implications for neurodegenerative diseases.
Chen S, Brown IR
Cell Stress Chaperones. 2007
PubMed ID: 17441507
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
Molecular profiles of mitogen activated protein kinase signaling pathways in orofacial development.
Singh S, Yin X, Pisano MM, Greene RM
Birth Defects Res A Clin Mol Teratol. 2007
PubMed ID: 17177285
Overexpression of human 27 kDa heat shock protein in laryngeal cancer cells confers chemoresistance associated with cell growth delay.
Lee JH, Sun D, Cho KJ, Kim MS, Hong MH, Kim IK, Lee JS, Lee JH
J Cancer Res Clin Oncol. 2007
PubMed ID: 16906418
Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27.
Venkatakrishnan CD, Tewari AK, Moldovan L, Cardounel AJ, Zweier JL, Kuppusamy P, Ilangovan G
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16782845
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
Influx of macrophages into livers of rats treated with hepatotoxicants (thioacetamide, allyl alcohol, D-galactosamine) induces expression of HSP25.
Zborek A, Malusecka E, Rusin A, Krzyzowska-Gruca S, Krawczyk Z
J Mol Histol. 2006
PubMed ID: 17103249
Radioprotective effect of heat shock protein 25 on submandibular glands of rats.
Lee HJ, Lee YJ, Kwon HC, Bae S, Kim SH, Min JJ, Cho CK, Lee YS
Am J Pathol. 2006
PubMed ID: 17071584
Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27.
Rafiee P, Theriot ME, Nelson VM, Heidemann J, Kanaa Y, Horowitz SA, Rogaczewski A, Johnson CP, Ali I, Shaker R, Binion DG
Am J Physiol Cell Physiol. 2006
PubMed ID: 16790501
A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP
Nat Biotechnol. 2006
PubMed ID: 16964243
Abnormal small heat shock protein interactions involving neuropathy-associated HSP22 (HSPB8) mutants.
Fontaine JM, Sun X, Hoppe AD, Simon S, Vicart P, Welsh MJ, Benndorf R
FASEB J. 2006
PubMed ID: 16935933
Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress.
Vertii A, Hakim C, Kotlyarov A, Gaestel M
J Biol Chem. 2006
PubMed ID: 16840785
Suppression of NF-kappaB activation by Entamoeba histolytica in intestinal epithelial cells is mediated by heat shock protein 27.
Kammanadiminti SJ, Chadee K
J Biol Chem. 2006
PubMed ID: 16840786
Heat shock protein 27 is involved in neurite extension and branching of dorsal root ganglion neurons in vitro.
Williams KL, Rahimtula M, Mearow KM
J Neurosci Res. 2006
PubMed ID: 16862544
Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome.
Park HK, Park EC, Bae SW, Park MY, Kim SW, Yoo HS, Tudev M, Ko YH, Choi YH, Kim S, Kim DI, Kim YW, Lee BB, Yoon JB, Park JE
Circulation. 2006
PubMed ID: 16923754
Elevated serum kininogen in patients with Paget's disease of bone: a role in marrow stromal/preosteoblast cell proliferation.
Tsuruga E, Rao DS, Baatz JE, Reddy SV
J Cell Biochem. 2006
PubMed ID: 16598774
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y
Mol Cell. 2006
PubMed ID: 16916647
Heat induction of heat shock protein 25 requires cellular glutamine in intestinal epithelial cells.
Phanvijhitsiri K, Musch MW, Ropeleski MJ, Chang EB
Am J Physiol Cell Physiol. 2006
PubMed ID: 16554407
Short-chain fatty acid mediated phosphorylation of heat shock protein 25: effects on camptothecin-induced apoptosis.
Parhar K, Baer KA, Parker K, Ropeleski MJ
Am J Physiol Gastrointest Liver Physiol. 2006
PubMed ID: 16469826
A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.
Croci L, Chung SH, Masserdotti G, Gianola S, Bizzoca A, Gennarini G, Corradi A, Rossi F, Hawkes R, Consalez GG
Development. 2006
PubMed ID: 16774995
Heat shock protein 25 or inducible heat shock protein 70 activates heat shock factor 1: dephosphorylation on serine 307 through inhibition of ERK1/2 phosphorylation.
Seo HR, Chung DY, Lee YJ, Lee DH, Kim JI, Bae S, Chung HY, Lee SJ, Jeoung D, Lee YS
J Biol Chem. 2006
PubMed ID: 16624816
Biological significance of decreased HSP27 in human atherosclerosis.
Martin-Ventura JL, Nicolas V, Houard X, Blanco-Colio LM, Leclercq A, Egido J, Vranckx R, Michel JB, Meilhac O
Arterioscler Thromb Vasc Biol. 2006
PubMed ID: 16574891
MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer.
Xu L, Chen S, Bergan RC
Oncogene. 2006
PubMed ID: 16407830
Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.
Hoffert JD, Pisitkun T, Wang G, Shen RF, Knepper MA
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16641100
Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.
Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ
Invest Ophthalmol Vis Sci. 2006
PubMed ID: 16638982
Novel role for STAT-5B in the regulation of Hsp27-FGF-2 axis facilitating thrombin-induced vascular smooth muscle cell growth and motility.
Cao H, Dronadula N, Rizvi F, Li Q, Srivastava K, Gerthoffer WT, Rao GN
Circ Res. 2006
PubMed ID: 16527988
Phosphoproteome analysis of the human mitotic spindle.
Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16565220
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.
Leong WF, Chow VT
Cell Microbiol. 2006
PubMed ID: 16548883
Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells.
Tao Y, Drabik KA, Waypa TS, Musch MW, Alverdy JC, Schneewind O, Chang EB, Petrof EO
Am J Physiol Cell Physiol. 2006
PubMed ID: 16306130
Self-association and chaperone activity of Hsp27 are thermally activated.
Lelj-Garolla B, Mauk AG
J Biol Chem. 2006
PubMed ID: 16436384
Heat-shock protein 27 is a major methylglyoxal-modified protein in endothelial cells.
Schalkwijk CG, van Bezu J, van der Schors RC, Uchida K, Stehouwer CD, van Hinsbergh VW
FEBS Lett. 2006
PubMed ID: 16487519
p27Cip/Kip is involved in hsp25 or inducible hsp70 mediated adaptive response by low dose radiation.
Seo HR, Chung HY, Lee YJ, Bae S, Lee SJ, Lee YS
J Radiat Res (Tokyo). 2006
PubMed ID: 16571921
Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values.
Luk JM, Lam CT, Siu AF, Lam BY, Ng IO, Hu MY, Che CM, Fan ST
Proteomics. 2006
PubMed ID: 16400691
Hsp27 enhances recovery of splicing as well as rephosphorylation of SRp38 after heat shock.
Marin-Vinader L, Shin C, Onnekink C, Manley JL, Lubsen NH
Mol Biol Cell. 2006
PubMed ID: 16339078
Arsenite pre-conditioning reduces UVB-induced apoptosis in corneal epithelial cells through the anti-apoptotic activity of 27 kDa heat shock protein (HSP27).
Shi B, Isseroff RR
J Cell Physiol. 2006
PubMed ID: 16114012
A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes.
Ackerley S, James PA, Kalli A, French S, Davies KE, Talbot K
Hum Mol Genet. 2006
PubMed ID: 16368711
Stress-induced heat shock protein 27 expression and its role in dorsal root ganglion neuronal survival.
Dodge ME, Wang J, Guy C, Rankin S, Rahimtula M, Mearow KM
Brain Res. 2006
PubMed ID: 16376863
Expression of Hsp70 and Hsp27 in lens epithelial cells in contused eye of rat modulated by thermotolerance or quercetin.
Yao K, Rao H, Wu R, Tang X, Xu W
Mol Vis. 2006
PubMed ID: 16710168
Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell.
Bausero MA, Bharti A, Page DT, Perez KD, Eng JW, Ordonez SL, Asea EE, Jantschitsch C, Kindas-Muegge I, Ciocca D, Asea A
Tumour Biol. 2006
PubMed ID: 16340246
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.
McCracken S, Longman D, Marcon E, Moens P, Downey M, Nickerson JA, Jessberger R, Wilde A, Caceres JF, Emili A, Blencowe BJ
J Biol Chem. 2005
PubMed ID: 16159877
Heat-shock protein 27: a potential biomarker for hepatocellular carcinoma identified by serum proteome analysis.
Feng JT, Liu YK, Song HY, Dai Z, Qin LX, Almofti MR, Fang CY, Lu HJ, Yang PY, Tang ZY
Proteomics. 2005
PubMed ID: 16240287
Large-scale analysis of the human ubiquitin-related proteome.
Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T, Nakayama KI
Proteomics. 2005
PubMed ID: 16196087
Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS.
Enokido Y, Suzuki E, Iwasawa K, Namekata K, Okazawa H, Kimura H
FASEB J. 2005
PubMed ID: 16160063
Dynamic expression of Hsp27 in the presence of mutant ataxin-3.
Chang WH, Cemal CK, Hsu YH, Kuo CL, Nukina N, Chang MH, Hu HT, Li C, Hsieh M
Biochem Biophys Res Commun. 2005
PubMed ID: 16126176
Development of Hsp25 expression compartments is not constrained by Purkinje cell defects in the Lurcher mouse mutant.
Armstrong CL, Vogel MW, Hawkes R
J Comp Neurol. 2005
PubMed ID: 16127699
[Mutation analysis of small heat shock protein 27 gene in Chinese patients with Charcot-Marie-Tooth disease]
Liu XM, Tang BS, Zhao GH, Xia K, Zhang FF, Pan Q, Cai F, Hu ZM, Zhang C, Chen B, Shen L, Zhang RX, Jiang H
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005
PubMed ID: 16215937
Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis.
Bruneel A, Labas V, Mailloux A, Sharma S, Royer N, Vinh J, Pernet P, Vaubourdolle M, Baudin B
Proteomics. 2005
PubMed ID: 16130169
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7.
Tsai HF, Lin SJ, Li C, Hsieh M
Biochem Biophys Res Commun. 2005
PubMed ID: 16039988
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.
Gevaert K, Staes A, Van Damme J, De Groot S, Hugelier K, Demol H, Martens L, Goethals M, Vandekerckhove J
Proteomics. 2005
PubMed ID: 16097034
Mutation analysis of the small heat shock protein 27 gene in chinese patients with Charcot-Marie-Tooth disease.
Tang B, Liu X, Zhao G, Luo W, Xia K, Pan Q, Cai F, Hu Z, Zhang C, Chen B, Zhang F, Shen L, Zhang R, Jiang H
Arch Neurol. 2005
PubMed ID: 16087758
Heat shock protein 27 is associated with freedom from graft vasculopathy after human cardiac transplantation.
De Souza AI, Wait R, Mitchell AG, Banner NR, Dunn MJ, Rose ML
Circ Res. 2005
PubMed ID: 15976317
Heat shock protein 27 in chronic allograft nephropathy: a local stress response.
Djamali A, Reese S, Oberley T, Hullett D, Becker B
Transplantation. 2005
PubMed ID: 15973165
Possible involvement of phosphatidylinositol 3-kinase/Akt signal pathway in vasopressin-induced HSP27 phosphorylation in aortic smooth muscle A10 cells.
Suga H, Nakajima K, Shu E, Kanno Y, Hirade K, Ishisaki A, Matsuno H, Tanabe K, Takai S, Akamatsu S, Kato K, Oiso Y, Kozawa O
Arch Biochem Biophys. 2005
PubMed ID: 15896702
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells.
McMullen ME, Bryant PW, Glembotski CC, Vincent PA, Pumiglia KM
J Biol Chem. 2005
PubMed ID: 15790570
p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli.
Hirano S, Sun X, DeGuzman CA, Ransom RF, McLeish KR, Smoyer WE, Shelden EA, Welsh MJ, Benndorf R
Am J Physiol Renal Physiol. 2005
PubMed ID: 15687248
HSP25 inhibits radiation-induced apoptosis through reduction of PKCdelta-mediated ROS production.
Lee YJ, Lee DH, Cho CK, Chung HY, Bae S, Jhon GJ, Soh JW, Jeoung DI, Lee SJ, Lee YS
Oncogene. 2005
PubMed ID: 15806174
HSP25 inhibits protein kinase C delta-mediated cell death through direct interaction.
Lee YJ, Lee DH, Cho CK, Bae S, Jhon GJ, Lee SJ, Soh JW, Lee YS
J Biol Chem. 2005
PubMed ID: 15731106
A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D.
Döppler H, Storz P, Li J, Comb MJ, Toker A
J Biol Chem. 2005
PubMed ID: 15728188
Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72.
Arvans DL, Vavricka SR, Ren H, Musch MW, Kang L, Rocha FG, Lucioni A, Turner JR, Alverdy J, Chang EB
Am J Physiol Gastrointest Liver Physiol. 2005
PubMed ID: 15528251
Substitution of the unique cysteine residue of murine Hsp25 interferes with the protective activity of this stress protein through inhibition of dimer formation.
Diaz-Latoud C, Buache E, Javouhey E, Arrigo AP
Antioxid Redox Signal. 2005
PubMed ID: 15706091
Modulation of estrogen signaling by the novel interaction of heat shock protein 27, a biomarker for atherosclerosis, and estrogen receptor beta: mechanistic insight into the vascular effects of estrogens.
Miller H, Poon S, Hibbert B, Rayner K, Chen YX, O'Brien ER
Arterioscler Thromb Vasc Biol. 2005
PubMed ID: 15662019
Mechanism of chaperone function in small heat shock proteins: dissociation of the HSP27 oligomer is required for recognition and binding of destabilized T4 lysozyme.
Shashidharamurthy R, Koteiche HA, Dong J, McHaourab HS
J Biol Chem. 2005
PubMed ID: 15542604
The kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs.
McCormick C, Ganem D
Science. 2005
PubMed ID: 15692053
Cytotoxic effects induced by oxidative stress in cultured mammalian cells and protection provided by Hsp27 expression.
Arrigo AP, Firdaus WJ, Mellier G, Moulin M, Paul C, Diaz-latoud C, Kretz-remy C
Methods. 2005
PubMed ID: 15649839
Self-association of a small heat shock protein.
Lelj-Garolla B, Mauk AG
J Mol Biol. 2005
PubMed ID: 15581903
Heat shock protein 25 plays multiple roles during mouse skin development.
Duverger O, Morange M
Cell Stress Chaperones. 2005
PubMed ID: 16333981
Heat shock protein 27 expression in patients with chronic liver damage.
Federico A, Tuccillo C, Terracciano F, D'Alessio C, Galdiero M, Finamore E, D'Isanto M, Peluso L, Del Vecchio Blanco C, Loguercio C
Immunobiology. 2005
PubMed ID: 15969449
Hsp27 and axonal growth in adult sensory neurons in vitro.
Williams KL, Rahimtula M, Mearow KM
BMC Neurosci. 2005
PubMed ID: 15819993
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.
Min JN, Zhang Y, Moskophidis D, Mivechi NF
Genesis. 2004
PubMed ID: 15593327
Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis.
Strey CW, Spellman D, Stieber A, Gonatas JO, Wang X, Lambris JD, Gonatas NK
Am J Pathol. 2004
PubMed ID: 15509539
HSP25 protects skeletal muscle cells against oxidative stress.
Escobedo J, Pucci AM, Koh TJ
Free Radic Biol Med. 2004
PubMed ID: 15454285
Regulation of Hsp27 expression and cell survival by the POU transcription factor Brn3a.
Farooqui-Kabir SR, Budhram-Mahadeo V, Lewis H, Latchman DS, Marber MS, Heads RJ
Cell Death Differ. 2004
PubMed ID: 15272315
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Heat stress-induced localization of small heat shock proteins in mouse myoblasts: intranuclear lamin A/C speckles as target for alphaB-crystallin and Hsp25.
Adhikari AS, Sridhar Rao K, Rangaraj N, Parnaik VK, Mohan Rao Ch
Exp Cell Res. 2004
PubMed ID: 15350538
Further mapping and characterization of Naq1, a quantitative trait locus responsible for maternal inferior nurturing ability in RR mice.
Suto J, Sekikawa K
J Vet Med Sci. 2004
PubMed ID: 15472464
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S
Genome Res. 2004
PubMed ID: 15342556
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15302935
Protective role of HSP27 against UVC-induced cell death in human cells.
Wano C, Kita K, Takahashi S, Sugaya S, Hino M, Hosoya H, Suzuki N
Exp Cell Res. 2004
PubMed ID: 15265704
Expression of heat shock protein 27 in human renal cell carcinoma.
Sarto C, Valsecchi C, Magni F, Tremolada L, Arizzi C, Cordani N, Casellato S, Doro G, Favini P, Perego RA, Raimondo F, Ferrero S, Mocarelli P, Galli-Kienle M
Proteomics. 2004
PubMed ID: 15274119
Inactivity-induced modulation of Hsp20 and Hsp25 content in rat hindlimb muscles.
Huey KA, Thresher JS, Brophy CM, Roy RR
Muscle Nerve. 2004
PubMed ID: 15221884
Bacterial superantigen-treated intestinal epithelial cells upregulate heat shock proteins 25 and 72 and are resistant to oxidant cytotoxicity.
Musch MW, Petrof EO, Kojima K, Ren H, McKay DM, Chang EB
Infect Immun. 2004
PubMed ID: 15155620
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Evgrafov OV, Mersiyanova I, Irobi J, Van Den Bosch L, Dierick I, Leung CL, Schagina O, Verpoorten N, Van Impe K, Fedotov V, Dadali E, Auer-Grumbach M, Windpassinger C, Wagner K, Mitrovic Z, Hilton-Jones D, Talbot K, Martin JJ, Vasserman N, Tverskaya S, Polyakov A, Liem RK, Gettemans J, Robberecht W, De Jonghe P, Timmerman V
Nat Genet. 2004
PubMed ID: 15122254
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy.
Irobi J, Van Impe K, Seeman P, Jordanova A, Dierick I, Verpoorten N, Michalik A, De Vriendt E, Jacobs A, Van Gerwen V, Vennekens K, Mazanec R, Tournev I, Hilton-Jones D, Talbot K, Kremensky I, Van Den Bosch L, Robberecht W, Van Vandekerckhove J, Van Broeckhoven C, Gettemans J, De Jonghe P, Timmerman V
Nat Genet. 2004
PubMed ID: 15122253
Confirmation and dissection of QTL controlling resistance to malaria in mice.
Hernandez-Valladares M, Naessens J, Gibson JP, Musoke AJ, Nagda S, Rihet P, Ole-MoiYoi OK, Iraqi FA
Mamm Genome. 2004
PubMed ID: 15170228
Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury.
Sumioka I, Matsura T, Kai M, Yamada K
Life Sci. 2004
PubMed ID: 15010265
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Differential expression of the MAD2, BUB1 and HSP27 genes in Barrett's oesophagus-their association with aneuploidy and neoplastic progression.
Doak SH, Jenkins GJ, Parry EM, Griffiths AP, Baxter JN, Parry JM
Mutat Res. 2004
PubMed ID: 15013707
HSP25 is involved in two steps of the differentiation of PAM212 keratinocytes.
Duverger O, Paslaru L, Morange M
J Biol Chem. 2004
PubMed ID: 14662766
Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions.
Koh TJ, Escobedo J
Am J Physiol Cell Physiol. 2004
PubMed ID: 14627610
HSP25 overexpression attenuates oxidative stress-induced apoptosis: roles of ERK1/2 signaling and manganese superoxide dismutase.
Lee YJ, Cho HN, Jeoung DI, Soh JW, Cho CK, Bae S, Chung HY, Lee SJ, Lee YS
Free Radic Biol Med. 2004
PubMed ID: 14975446
Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells.
Song H, Ethier SP, Dziubinski ML, Lin J
Biochem Biophys Res Commun. 2004
PubMed ID: 14715258
Interaction of human HSP22 (HSPB8) with other small heat shock proteins.
Sun X, Fontaine JM, Rest JS, Shelden EA, Welsh MJ, Benndorf R
J Biol Chem. 2004
PubMed ID: 14594798
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance.
Chauhan D, Li G, Hideshima T, Podar K, Mitsiades C, Mitsiades N, Catley L, Tai YT, Hayashi T, Shringarpure R, Burger R, Munshi N, Ohtake Y, Saxena S, Anderson KC
Blood. 2003
PubMed ID: 12855565
Suppression of thermotolerance in mumps virus-infected cells is caused by lack of HSP27 induction contributed by STAT-1.
Yokota S, Yokosawa N, Kubota T, Okabayashi T, Arata S, Fujii N
J Biol Chem. 2003
PubMed ID: 12917439
An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse.
Percec I, Thorvaldsen JL, Plenge RM, Krapp CJ, Nadeau JH, Willard HF, Bartolomei MS
Genetics. 2003
PubMed ID: 12930754
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation.
Parcellier A, Schmitt E, Gurbuxani S, Seigneurin-Berny D, Pance A, Chantôme A, Plenchette S, Khochbin S, Solary E, Garrido C
Mol Cell Biol. 2003
PubMed ID: 12897149
Induction of Hsp27 and Hsp32 stress proteins and vimentin in glial cells of the rat hippocampus following hyperthermia.
Bechtold DA, Brown IR
Neurochem Res. 2003
PubMed ID: 12834255
Heat shock protein 27 gene: chromosomal and molecular location and relationship to Williams syndrome.
Stock AD, Spallone PA, Dennis TR, Netski D, Morris CA, Mervis CB, Hobart HH
Am J Med Genet A. 2003
PubMed ID: 12838549
Heat shock protein 27 controls apoptosis by regulating Akt activation.
Rane MJ, Pan Y, Singh S, Powell DW, Wu R, Cummins T, Chen Q, McLeish KR, Klein JB
J Biol Chem. 2003
PubMed ID: 12740362
The DNA sequence of human chromosome 7.
Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S, Rohlfing T, Rock SM, Tin-Wollam AM, Abbott A, Minx P, Maupin R, Strowmatt C, Latreille P, Miller N, Johnson D, Murray J, Woessner JP, Wendl MC, Yang SP, Schultz BR, Wallis JW, Spieth J, Bieri TA, Nelson JO, Berkowicz N, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Bedell JA, Mardis ER, Clifton SW, Chissoe SL, Marra MA, Raymond C, Haugen E, Gillett W, Zhou Y, James R, Phelps K, Iadanoto S, Bubb K, Simms E, Levy R, Clendenning J, Kaul R, Kent WJ, Furey TS, Baertsch RA, Brent MR, Keibler E, Flicek P, Bork P, Suyama M, Bailey JA, Portnoy ME, Torrents D, Chinwalla AT, Gish WR, Eddy SR, McPherson JD, Olson MV, Eichler EE, Green ED, Waterston RH, Wilson RK
Nature. 2003
PubMed ID: 12853948
Adaptation to heat of cardiomyoblasts in culture protects them against heat shock: role of nitric oxide and heat shock proteins.
Monastyrskaya EA, Andreeva LV, Duchen MR, Wiegant F, Bayda LA, Manukhina EB, Malyshev IY
Biochemistry (Mosc). 2003
PubMed ID: 12946265
Analysis of the interaction of small heat shock proteins with unfolding proteins.
Stromer T, Ehrnsperger M, Gaestel M, Buchner J
J Biol Chem. 2003
PubMed ID: 12637495
Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis.
Wang G, Zhang J, Moskophidis D, Mivechi NF
Genesis. 2003
PubMed ID: 12748967
Interleukin-11-induced heat shock protein 25 confers intestinal epithelial-specific cytoprotection from oxidant stress.
Ropeleski MJ, Tang J, Walsh-Reitz MM, Musch MW, Chang EB
Gastroenterology. 2003
PubMed ID: 12730876
HSP27 is markedly induced in Schwann cell columns and associated regenerating axons.
Hirata K, He J, Hirakawa Y, Liu W, Wang S, Kawabuchi M
Glia. 2003
PubMed ID: 12594732
Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function.
Shin BK, Wang H, Yim AM, Le Naour F, Brichory F, Jang JH, Zhao R, Puravs E, Tra J, Michael CW, Misek DE, Hanash SM
J Biol Chem. 2003
PubMed ID: 12493773
Different expression of 25-kDa heat-shock protein (Hsp25) in Meckel's cartilage compared with other cartilages in the mouse.
Shimada M, Yamamoto M, Wakayama T, Iseki S, Amano O
Anat Embryol (Berl). 2003
PubMed ID: 12592567
Possible role of immunocompetent cells and the expression of heat shock protein-25 in the process of pulpal regeneration after tooth injury in rat molars.
Nakakura-Ohshima K, Watanabe J, Kenmotsu S, Ohshima H
J Electron Microsc (Tokyo). 2003
PubMed ID: 14756247
Administration of brain-derived neurotrophic factor suppresses the expression of heat shock protein 27 in rat retinal ganglion cells following axotomy.
Krueger-Naug AM, Emsley JG, Myers TL, Currie RW, Clarke DB
Neuroscience. 2003
PubMed ID: 12535937
Hsp27 associates with actin and limits injury in energy depleted renal epithelia.
Van Why SK, Mann AS, Ardito T, Thulin G, Ferris S, Macleod MA, Kashgarian M, Siegel NJ
J Am Soc Nephrol. 2003
PubMed ID: 12506142
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Heat-shock protein 25 (Hspb1) regulates manganese superoxide dismutase through activation of Nfkb (NF-kappaB).
Yi MJ, Park SH, Cho HN, Yong Chung H, Kim JI, Cho CK, Lee SJ, Lee YS
Radiat Res. 2002
PubMed ID: 12385642
Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival.
Benn SC, Perrelet D, Kato AC, Scholz J, Decosterd I, Mannion RJ, Bakowska JC, Woolf CJ
Neuron. 2002
PubMed ID: 12367505
Innervation-dependent phosphorylation and accumulation of alphaB-crystallin and Hsp27 as insoluble complexes in disused muscle.
Kato K, Ito H, Kamei K, Iwamoto I, Inaguma Y
FASEB J. 2002
PubMed ID: 12205038
Thrombin stimulates dissociation and induction of HSP27 via p38 MAPK in vascular smooth muscle cells.
Hirade K, Kozawa O, Tanabe K, Niwa M, Matsuno H, Oiso Y, Akamatsu S, Ito H, Kato K, Katagiri Y, Uematsu T
Am J Physiol Heart Circ Physiol. 2002
PubMed ID: 12181122
Heat shock protein-27 protects human bronchial epithelial cells against oxidative stress-mediated apoptosis: possible implication in asthma.
Merendino AM, Paul C, Vignola AM, Costa MA, Melis M, Chiappara G, Izzo V, Bousquet J, Arrigo AP
Cell Stress Chaperones. 2002
PubMed ID: 12482203
Subcorneal colocalization of the small heat shock protein, hsp27, with keratins and proteins of the cornified cell envelope.
Jonak C, Klosner G, Kokesch C, FOdinger D, HOnigsmann H, Trautinger F
Br J Dermatol. 2002
PubMed ID: 12100179
Critical involvement of p38 MAP kinase in pertussis toxin-induced cytoskeletal reorganization and lung permeability.
Garcia JG, Wang P, Schaphorst KL, Becker PM, Borbiev T, Liu F, Birukova A, Jacobs K, Bogatcheva N, Verin AD
FASEB J. 2002
PubMed ID: 12087068
S-thiolation of HSP27 regulates its multimeric aggregate size independently of phosphorylation.
Eaton P, Fuller W, Shattock MJ
J Biol Chem. 2002
PubMed ID: 11925435
Hsp25 regulates the expression of p21(Waf1/Cip1/Sdi1) through multiple mechanisms.
Park SH, Lee YS, Osawa Y, Hachiya M, Akashi M
J Biochem. 2002
PubMed ID: 12038984
Phosphorylation-dependent cellular localization and thermoprotective role of heat shock protein 25 in hippocampal progenitor cells.
Geum D, Son GH, Kim K
J Biol Chem. 2002
PubMed ID: 11912188
Differential expression of heat shock protein 27 in normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma.
Leonardi R, Pannone G, Magro G, Kudo Y, Takata T, Lo Muzio L
Oncol Rep. 2002
PubMed ID: 11836590
Detection of protein-protein interactions among lens crystallins in a mammalian two-hybrid system assay.
Fu L, Liang JJ
J Biol Chem. 2002
PubMed ID: 11700327
Hsp27 as a negative regulator of cytochrome C release.
Paul C, Manero F, Gonin S, Kretz-Remy C, Virot S, Arrigo AP
Mol Cell Biol. 2002
PubMed ID: 11784858
Expression of heat-shock protein 25 immunoreactivity in the dental pulp and enamel organ during odontogenesis in the rat molar.
Ohshima H, Nakakura-Ohshima K, Maeda T
Connect Tissue Res. 2002
PubMed ID: 12489163
Overexpression of Hsp25 in K1735 murine melanoma cells enhances susceptibility to natural killer cytotoxicity.
Jantschitsch C, Trautinger F, Klosner G, Gsur A, Herbacek I, Micksche M, Kindås-Mügge I
Cell Stress Chaperones. 2002
PubMed ID: 11892982
Characterization of proteins associated with heat shock protein hsp27 in the squamous cell carcinoma cell line A431.
Kindas-Mügge I, Rieder C, Fröhlich I, Micksche M, Trautinger F, Riedler C
Cell Biol Int. 2002
PubMed ID: 11779227
Expression pattern of HSP25 in mouse preimplantation embryo: heat shock responses during oocyte maturation.
Kim M, Geum D, Khang I, Park YM, Kang BM, Lee KA, Kim K
Mol Reprod Dev. 2002
PubMed ID: 11774370
Identification and characterization of hic-5/ARA55 as an hsp27 binding protein.
Jia Y, Ransom RF, Shibanuma M, Liu C, Welsh MJ, Smoyer WE
J Biol Chem. 2001
PubMed ID: 11546764
Phosphatase inhibitors prevent HSP27 dephosphorylation, destruction of stress fibrils, and morphological changes in endothelial cells during ATP depletion.
Loktionova SA, Kabakov AE
Bull Exp Biol Med. 2001
PubMed ID: 11740592
A new locus for autosomal dominant Charcot-Marie-Tooth disease type 2 (CMT2F) maps to chromosome 7q11-q21.
Ismailov SM, Fedotov VP, Dadali EL, Polyakov AV, Van Broeckhoven C, Ivanov VI, De Jonghe P, Timmerman V, Evgrafov OV
Eur J Hum Genet. 2001
PubMed ID: 11528513
HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27).
Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ
J Biol Chem. 2001
PubMed ID: 11342557
Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse.
Armstrong CL, Krueger-Naug AM, Currie RW, Hawkes R
J Comp Neurol. 2001
PubMed ID: 11331528
Adaptive mechanisms that preserve cardiac function in mice without myoglobin.
Meeson AP, Radford N, Shelton JM, Mammen PP, DiMaio JM, Hutcheson K, Kong Y, Elterman J, Williams RS, Garry DJ
Circ Res. 2001
PubMed ID: 11304494
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils.
Rane MJ, Coxon PY, Powell DW, Webster R, Klein JB, Pierce W, Ping P, McLeish KR
J Biol Chem. 2001
PubMed ID: 11042204
Protein-protein interactions with subunits of human nuclear RNase P.
Jiang T, Altman S
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11158571
Expression of heat-shock protein Hsp25 in mouse Purkinje cells during development reveals novel features of cerebellar compartmentation.
Armstrong CL, Krueger-Naug AM, Currie RW, Hawkes R
J Comp Neurol. 2001
PubMed ID: 11086286
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG
Mech Dev. 2000
PubMed ID: 11044609
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Inhibition of Daxx-mediated apoptosis by heat shock protein 27.
Charette SJ, Lavoie JN, Lambert H, Landry J
Mol Cell Biol. 2000
PubMed ID: 11003656
Hsp27 negatively regulates cell death by interacting with cytochrome c.
Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, Gurbuxani S, Arrigo AP, Kroemer G, Solary E, Garrido C
Nat Cell Biol. 2000
PubMed ID: 10980706
Heat shock factor 2 is activated during mouse heart development.
Eriksson M, Jokinen E, Sistonen L, Leppä S
Int J Dev Biol. 2000
PubMed ID: 11032181
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27.
Liu C, Gilmont RR, Benndorf R, Welsh MJ
J Biol Chem. 2000
PubMed ID: 10751411
Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes.
Cuesta R, Laroia G, Schneider RJ
Genes Dev. 2000
PubMed ID: 10859165
Identification of four new quantitative trait loci regulating arthritis severity and one new quantitative trait locus regulating autoantibody production in rats with collagen-induced arthritis.
Griffiths MM, Wang J, Joe B, Dracheva S, Kawahito Y, Shepard JS, Reese VR, McCall-Vining S, Hashiramoto A, Cannon GW, Remmers EF, Wilder RL
Arthritis Rheum. 2000
PubMed ID: 10857786
Small heat shock protein 27 (HSP27) associates with tubulin/microtubules in HeLa cells.
Hino M, Kurogi K, Okubo MA, Murata-Hori M, Hosoya H
Biochem Biophys Res Commun. 2000
PubMed ID: 10777697
Heat-shock proteins associated with base excision repair enzymes in HeLa cells.
Mendez F, Sandigursky M, Franklin WA, Kenny MK, Kureekattil R, Bases R
Radiat Res. 2000
PubMed ID: 10629618
Characterization of native interaction of hsp110 with hsp25 and hsc70.
Wang XY, Chen X, Oh HJ, Repasky E, Kazim L, Subjeck J
FEBS Lett. 2000
PubMed ID: 10631312
Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation.
Sugiyama Y, Suzuki A, Kishikawa M, Akutsu R, Hirose T, Waye MM, Tsui SK, Yoshida S, Ohno S
J Biol Chem. 2000
PubMed ID: 10625651
The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis.
Charette SJ, Landry J
Ann N Y Acad Sci. 2000
PubMed ID: 11193028
HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice.
Xiao X, Zuo X, Davis AA, McMillan DR, Curry BB, Richardson JA, Benjamin IJ
EMBO J. 1999
PubMed ID: 10545106
Two-dimensional gel analysis of human endometrial proteins: characterization of proteins with increased expression in hyperplasia and adenocarcinoma.
Byrjalsen I, Mose Larsen P, Fey SJ, Nilas L, Larsen MR, Christiansen C
Mol Hum Reprod. 1999
PubMed ID: 10421803
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation.
Rogalla T, Ehrnsperger M, Preville X, Kotlyarov A, Lutsch G, Ducasse C, Paul C, Wieske M, Arrigo AP, Buchner J, Gaestel M
J Biol Chem. 1999
PubMed ID: 10383393
Specific expression of the mRNA for 25 kDA heat-shock protein in the spermatocytes of mouse seminiferous tubules.
Wakayama T, Iseki S
Anat Embryol (Berl). 1999
PubMed ID: 10221453
Cloning and characterization of RLPK, a novel RSK-related protein kinase.
New L, Zhao M, Li Y, Bassett WW, Feng Y, Ludwig S, Padova FD, Gram H, Han J
J Biol Chem. 1999
PubMed ID: 9873047
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Hsp and chaperone distribution during endochondral bone development in mouse embryo.
Loones MT, Morange M
Cell Stress Chaperones. 1998
PubMed ID: 9880236
PRAK, a novel protein kinase regulated by the p38 MAP kinase.
New L, Jiang Y, Zhao M, Liu K, Zhu W, Flood LJ, Kato Y, Parry GC, Han J
EMBO J. 1998
PubMed ID: 9628874
Expression and cellular localization of the mRNA for the 25-kDa heat-shock protein in the mouse.
Wakayama T, Iseki S
Cell Biol Int. 1998
PubMed ID: 10101046
Assignment of the mouse Hsp25 and Hsp105 genes to the distal region of chromosome 5 by linkage analysis.
Hunt CR, Goswami PC, Kozak CA
Genomics. 1997
PubMed ID: 9344682
Large-scale concatenation cDNA sequencing.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA
Genome Res. 1997
PubMed ID: 9110174
Function and regulation of heat shock factor 2 during mouse embryogenesis.
Rallu M, Loones M, Lallemand Y, Morimoto R, Morange M, Mezger V
Proc Natl Acad Sci U S A. 1997
PubMed ID: 9122205
A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress.
Clifton AD, Young PR, Cohen P
FEBS Lett. 1996
PubMed ID: 8774846
Variation in expression of hsp27 messenger ribonucleic acid during the cycle of the seminiferous epithelium and co-localization of hsp27 and microfilaments in Sertoli cells of the rat.
Welsh MJ, Wu W, Parvinen M, Gilmont RR
Biol Reprod. 1996
PubMed ID: 8793069
A "double adaptor" method for improved shotgun library construction.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA
Anal Biochem. 1996
PubMed ID: 8619474
Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27.
Lavoie JN, Lambert H, Hickey E, Weber LA, Landry J
Mol Cell Biol. 1995
PubMed ID: 7799959
Differential estrogenic regulation of small M(r) heat shock protein expression in osteoblasts.
Cooper LF, Uoshima K
J Biol Chem. 1994
PubMed ID: 8132504
Isolation and characterization of a rat HSP 27 gene.
Uoshima K, Handelman B, Cooper LF
Biochem Biophys Res Commun. 1993
PubMed ID: 7916612
Physiological and pathological changes in levels of the two small stress proteins, HSP27 and alpha B crystallin, in rat hindlimb muscles.
Inaguma Y, Goto S, Shinohara H, Hasegawa K, Ohshima K, Kato K
J Biochem. 1993
PubMed ID: 8282729
The 28-kDa protein whose phosphorylation is induced by protein kinase C activators in MCF-7 cells belongs to the family of low molecular mass heat shock proteins and is the estrogen-regulated 24-kDa protein.
Faucher C, Capdevielle J, Canal I, Ferrara P, Mazarguil H, McGuire WL, Darbon JM
J Biol Chem. 1993
PubMed ID: 8325890
Structure and organisation of a murine gene encoding small heat-shock protein Hsp25.
Gaestel M, Gotthardt R, Müller T
Gene. 1993
PubMed ID: 8514194
Cloning of the mouse hsp25 gene and an extremely conserved hsp25 pseudogene.
Fröhli E, Aoyama A, Klemenz R
Gene. 1993
PubMed ID: 8514193
Expression of the murine small heat shock proteins hsp 25 and alpha B crystallin in the absence of stress.
Klemenz R, Andres AC, Fröhli E, Schäfer R, Aoyama A
J Cell Biol. 1993
PubMed ID: 8425893
Small heat shock proteins are molecular chaperones.
Jakob U, Gaestel M, Engel K, Buchner J
J Biol Chem. 1993
PubMed ID: 8093612
Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins.
Stokoe D, Engel K, Campbell DG, Cohen P, Gaestel M
FEBS Lett. 1992
PubMed ID: 1332886
Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.
Dawson SJ, White LA
J Infect. 1992
PubMed ID: 1602151
Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.
Kato K, Shinohara H, Goto S, Inaguma Y, Morishita R, Asano T
J Biol Chem. 1992
PubMed ID: 1560006
Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II.
Landry J, Lambert H, Zhou M, Lavoie JN, Hickey E, Weber LA, Anderson CW
J Biol Chem. 1992
PubMed ID: 1730670
The 29-kDa proteins phosphorylated in thrombin-activated human platelets are forms of the estrogen receptor-related 27-kDa heat shock protein.
Mendelsohn ME, Zhu Y, O'Neill S
Proc Natl Acad Sci U S A. 1991
PubMed ID: 1763035
Identification of the phosphorylation sites of the murine small heat shock protein hsp25.
Gaestel M, Schröder W, Benndorf R, Lippmann C, Buchner K, Hucho F, Erdmann VA, Bielka H
J Biol Chem. 1991
PubMed ID: 1860870
cDNA sequence of a human heat shock protein HSP27.
Carper SW, Rocheleau TA, Storm FK
Nucleic Acids Res. 1990
PubMed ID: 2243808
Identification of two related markers for common acute lymphoblastic leukemia as heat shock proteins.
Strahler JR, Kuick R, Eckerskorn C, Lottspeich F, Richardson BC, Fox DA, Stoolman LM, Hanson CA, Nichols D, Tueche HJ
J Clin Invest. 1990
PubMed ID: 2295696
Induction of the estrogen-regulated "24K" protein by heat shock.
Fuqua SA, Blum-Salingaros M, McGuire WL
Cancer Res. 1989
PubMed ID: 2743305
Molecular cloning, sequencing and expression in Escherichia coli of the 25-kDa growth-related protein of Ehrlich ascites tumor and its homology to mammalian stress proteins.
Gaestel M, Gross B, Benndorf R, Strauss M, Schunk WH, Kraft R, Otto A, Böhm H, Stahl J, Drabsch H
Eur J Biochem. 1989
PubMed ID: 2645135
Sequence and organization of genes encoding the human 27 kDa heat shock protein.
Hickey E, Brandon SE, Potter R, Stein G, Stein J, Weber LA
Nucleic Acids Res. 1986
PubMed ID: 3714473

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	3315	15507	24471
EnsEMBL Gene(s)	ENSG00000106211	ENSMUSG00000004951	ENSRNOG00000023546
Unigene	Hs.520973	Mm.13849	Rn.3841
Homologene	HSPB1	Hspb1	Hspb1
OMIM	602195	N/A	N/A
GeneCards	HSPB1	N/A	N/A
Beta Cell Genomics	DT.101986742 DT.91648006 DT.95186317 DT.97869739	DT.101401203 DT.110958980 DT.94158947 DT.94158949 DT.97368839	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	ENSP00000248553	N/A	N/A
WikiGenes	3315	15507	24471

External resources from NIDDK Consortium Interconnectivity Network Top Help

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View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
HSPB1	HDAC6	BioGRID	empirical	22238643
HSPB1	POP7	HPRD	empirical	11158571
HSPB1	SAP18	IntAct	empirical	17353931
HSPB1	CFTR	IntAct	empirical	17110338
HSPB1	YWHAQ	BioGRID	empirical	20618440
HSPB1	GABARAPL2	IntAct	empirical	20562859
HSPB1	CRYAA	HPRD, MINT, BioGRID	empirical	11700327
HSPB1	CRYAB	HPRD, MINT, BioGRID	empirical	1560006 11700327
HSPB1	CRYBB2	HPRD, MINT, BioGRID	empirical	11700327
HSPB1	CRYGC	HPRD	empirical	11700327
HSPB1	DAXX	HPRD, IntAct	empirical	11193028 11003656
HSPB1	DMWD	IntAct, BioGRID	empirical	19615732
HSPB1	EGFR	IntAct	empirical	15657067
HSPB1	EIF4G1	HPRD, MINT, Reactome	empirical	10859165 18573886 16556936 12819195 10205060
HSPB1	AKT1	BioGRID	empirical	11042204
HSPB1	RPGRIP1L	IntAct	empirical	21565611
HSPB1	SRRM2	BioGRID	empirical	16159877
HSPB1	GABARAPL1	IntAct	empirical	20562859
HSPB1	G6PD	BioGRID	empirical	21157431
HSPB1	NPHP4	IntAct	empirical	21565611
HSPB1	GATA1	BioGRID	empirical	20410505
HSPB1	HSPB8	HPRD, IntAct, BioGRID	empirical	11342557 14594798 15122253
HSPB1	PABPC1	Reactome	predicted	18573886 16556936 12819195 10205060
HSPB1	GRB2	IntAct	empirical	12577067
HSPB1	SERTAD1	IntAct	empirical	21988832
HSPB1	HNRNPD	BioGRID	empirical	18573886 21245386
HSPB1	HSF1	BioGRID	empirical	19597476
HSPB1	HSPA1B	Reactome	predicted	18573886 16556936 12819195 10205060
HSPB1	HSPA8	Reactome	predicted	18573886 16556936 12819195 10205060
HSPB1	HSPB1	IntAct	empirical	11003656
HSPB1	ILK	IntAct, BioGRID	empirical	17353931
HSPB1	LBP	IntAct	empirical	21988832
HSPB1	MAGEA6	IntAct	empirical	17353931
HSPB1	MME	IntAct, BioGRID	empirical	17342744
HSPB1	MYC	IntAct, BioGRID	empirical	17314511 21150319
HSPB1	NFKBIA	HPRD	empirical	12897149
HSPB1	MED31	HPRD, MINT, IntAct, BioGRID	empirical	16169070
HSPB1	UCHL5	BioGRID	empirical	21800051
HSPB1	CYCS	HPRD, BioGRID	empirical	10980706 11784858
HSPB1	PPA1	HPRD, IntAct, BioGRID	empirical	16169070
HSPB1	PPM1A	IntAct	empirical	21988832
HSPB1	FAIM	Sanger Interaction Map	predicted	15345047
HSPB1	RIF1	IntAct	empirical	16169070
HSPB1	BRF2	IntAct	empirical	17353931
HSPB1	PRKAA1	IntAct	empirical	20368287
HSPB1	LRIF1	HPRD, MINT	empirical	16169070
HSPB1	PRKCD	BioGRID	empirical	15731106
HSPB1	PRKCE	IntAct	empirical	11139474
HSPB1	PRKD1	BioGRID	empirical	15728188
HSPB1	MAPK3	MINT	empirical	19935650
HSPB1	SLC2A4	IntAct	empirical	16396496
HSPB1	SMARCD1	IntAct	empirical	21988832
HSPB1	STAT2	BioGRID	empirical	22238643
HSPB1	STAT3	IntAct	empirical	15102471
HSPB1	STAT5B	Sanger Interaction Map	predicted	15345047
HSPB1	ACTC1	HPRD	empirical	12087068
HSPB1	TGFB1I1	HPRD, BioGRID	empirical	11546764
HSPB1	TGM1	HPRD	empirical	12100179
HSPB1	TNF	BioGRID	empirical	21245386
HSPB1	TP53	HPRD, MINT, IntAct, BioGRID	empirical	16169070 17184779
HSPB1	UBC	BioGRID	empirical	16196087 22178446 17623298 18781797 21987572 21139048 21906983
HSPB1	UBE2I	BioGRID	empirical	19597476
HSPB1	UNG	BioGRID	empirical	10629618
HSPB1	USP1	IntAct, BioGRID	empirical	19615732
HSPB1	YWHAZ	MINT	empirical	15161933
HSPB1	MAPKAPK3	HPRD, IntAct	empirical	8774846 21575178
HSPB1	MAP1LC3B	IntAct	empirical	20562859
HSPB1	CASP3	BioGRID	empirical	22238643
HSPB1	RBM48	HPRD, MINT, IntAct, BioGRID	empirical	16169070
HSPB1	SLX4	IntAct	empirical	19596235
HSPB1	MAP1LC3A	IntAct	empirical	20562859
HSPB1	USP38	IntAct, BioGRID	empirical	19615732
HSPB1	IGSF21	HPRD, MINT, IntAct, BioGRID	empirical	16169070
HSPB1	MAPKAPK5	HPRD, IntAct, BioGRID	empirical	9628874 17254968 21575178
HSPB1	TSC22D1	IntAct	empirical	17353931
HSPB1	RPS6KA5	BioGRID	empirical	9873047
HSPB1	MAPKAPK2	HPRD, IntAct, BioGRID	empirical	7799959 1332886 11042204 21575178
HSPB1	CIAO1	IntAct	empirical	17353931
HSPB1	MAGED1	IntAct, BioGRID	empirical	17353931
HSPB1	IQCB1	IntAct	empirical	21565611
HSPB1	PSMD6	IntAct	empirical	17353931