HOXA5

Summary from T1DBase Top Help

Gene Description:

homeobox A5; homeo box A5

Synonyms:

HOX1, HOX1C, HOX1.3, Hox-1.3, HOXA5, MGC9376, Hoxa5

Orthologs:

Human HOXA5 (protein-coding), Mouse Hoxa5 (protein-coding), Rat Hoxa5 (protein-coding)

Sources

Gene Overview from T1DBase Top Help

(Human) GRCh37 - chr7:27180671..27183287 (2.62 kb) View in Genome Browser

(Mouse) NCBIM37 - chr6:52151753..52154586 (2.83 kb) View in Genome Browser

Beta Cell Gene Atlas from T1DBase Top Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression Top Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

HaemAtlas Expression Top Help

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker	EB	MK	CD66b	CD14	CD19	CD8	CD4	CD56
Expression Pattern									HaemAtlasProfile

Expression Legend

Interactions from T1DBase Top Help

Interactions Table for HOXA5:

The HOXA5 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.

The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.

Interactor	Interactor	Sources	Classification	Pubmed IDs
HOXA5	CDX4	HPRD	empirical	15684390
HOXA5	GTF2A1L	BioGRID	empirical	20211142
HOXA5	FOXO1	HPRD, BioGRID	empirical	12163409
HOXA5	FOXA2	HPRD, BioGRID	empirical	12642491 12163409
HOXA5	SMAD1	BioGRID	empirical	20211142
HOXA5	MEIS1	HPRD, IntAct	empirical	15617687
HOXA5	PBX1	HPRD, BioGRID	empirical	8657138 20211142
HOXA5	TWIST1	HPRD	empirical	15545268
HOXA5	ZNF408	BioGRID	empirical	20211142

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 33

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 33
Skeletal system development	GO:0001501
Morphogenesis of an epithelium	GO:0002009
Respiratory system process	GO:0003016
DNA binding	GO:0003677
Sequence-specific DNA binding transcription factor activity	GO:0003700
Protein binding	GO:0005515
Nucleus	GO:0005634
Transcription, DNA-dependent	GO:0006351
Pattern specification process	GO:0007389
Anterior/posterior pattern specification	GO:0009952
Positive regulation of receptor biosynthetic process	GO:0010870
Cell migration	GO:0016477
Negative regulation of angiogenesis	GO:0016525
Thyroid gland development	GO:0030878
Regulation of mammary gland epithelial cell proliferation	GO:0033599
Multicellular organism growth	GO:0035264
Positive regulation of apoptosis	GO:0043065
Sequence-specific DNA binding	GO:0043565
Positive regulation of myeloid cell differentiation	GO:0045639
Negative regulation of erythrocyte differentiation	GO:0045647
Positive regulation of transcription from RNA polymerase II promoter	GO:0045944
Lung alveolus development	GO:0048286
Embryonic skeletal system morphogenesis	GO:0048704
Bronchiole development	GO:0060435
Epithelial tube branching involved in lung morphogenesis	GO:0060441
Lung goblet cell differentiation	GO:0060480
Lung-associated mesenchyme development	GO:0060484
Trachea cartilage morphogenesis	GO:0060535
Intestinal epithelial cell maturation	GO:0060574
Mesenchymal-epithelial cell signaling	GO:0060638
Mammary gland epithelial cell differentiation	GO:0060644
Mammary gland alveolus development	GO:0060749
Cell-cell signaling involved in mammary gland development	GO:0060764

Publications Top Help

Publications: 137

HOX genes in pancreatic development and cancer.
Gray S, Pandha HS, Michael A, Middleton G, Morgan R
JOP. 2011
PubMed ID: 21546695
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.
Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Xue S, Ishijima J, Shiroishi T, Barna M
Cell. 2011
PubMed ID: 21529712
Unsuspected effects of a lung-specific Cre deleter mouse line.
Jeannotte L, Aubin J, Bourque S, Lemieux M, Montaron S, Provencher St-Pierre A
Genesis. 2011
PubMed ID: 21309069
Androgen receptor mutations are associated with altered epigenomic programming as evidenced by HOXA5 methylation.
Bens S, Ammerpohl O, Martin-Subero JI, Appari M, Richter J, Hiort O, Werner R, Riepe FG, Siebert R, Holterhus PM
Sex Dev. 2011
PubMed ID: 21311178
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Transgenic over-expression of growth differentiation factor 11 propeptide in skeleton results in transformation of the seventh cervical vertebra into a thoracic vertebra.
Li Z, Kawasumi M, Zhao B, Moisyadi S, Yang J
Mol Reprod Dev. 2010
PubMed ID: 21049546
Level of HOXA5 hypermethylation in acute myeloid leukemia is associated with short-term outcome.
Kim SY, Hwang SH, Song EJ, Shin HJ, Jung JS, Lee EY
Korean J Lab Med. 2010
PubMed ID: 20890077
Epigenetic inactivation of HOXA5 and MSH2 gene in clear cell renal cell carcinoma.
Yoo KH, Park YK, Kim HS, Jung WW, Chang SG
Pathol Int. 2010
PubMed ID: 20846263
Global control of motor neuron topography mediated by the repressive actions of a single hox gene.
Jung H, Lacombe J, Mazzoni EO, Liem KF, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS
Neuron. 2010
PubMed ID: 20826310
An atlas of combinatorial transcriptional regulation in mouse and man.
Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
Cell. 2010
PubMed ID: 20211142
Influence of Hoxa5 on p53 tumorigenic outcome in mice.
Gendronneau G, Lemieux M, Morneau M, Paradis J, Têtu B, Frenette N, Aubin J, Jeannotte L
Am J Pathol. 2010
PubMed ID: 20042682
Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling.
Palmesino E, Rousso DL, Kao TJ, Klar A, Laufer E, Uemura O, Okamoto H, Novitch BG, Kania A
PLoS Biol. 2010
PubMed ID: 20711475
Multiple promoters and alternative splicing: Hoxa5 transcriptional complexity in the mouse embryo.
Coulombe Y, Lemieux M, Moreau J, Aubin J, Joksimovic M, Bérubé-Simard FA, Tabariès S, Boucherat O, Guillou F, Larochelle C, Tuggle CK, Jeannotte L
PLoS One. 2010
PubMed ID: 20485555
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Dev Cell. 2009
PubMed ID: 20059953
Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.
Ester AR, Weymouth KS, Burt A, Wise CA, Scott A, Gurnett CA, Dobbs MB, Blanton SH, Hecht JT
Am J Med Genet A. 2009
PubMed ID: 19938081
Epigenetic inactivation of Homeobox A5 gene in nonsmall cell lung cancer and its relationship with clinicopathological features.
Kim DS, Kim MJ, Lee JY, Lee SM, Choi JY, Yoon GS, Na YK, Hong HS, Kim SG, Choi JE, Lee SY, Park JY
Mol Carcinog. 2009
PubMed ID: 19554572
Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity.
Voss AK, Collin C, Dixon MP, Thomas T
Dev Cell. 2009
PubMed ID: 19922872
Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos.
Young T, Rowland JE, van de Ven C, Bialecka M, Novoa A, Carapuco M, van Nes J, de Graaff W, Duluc I, Freund JN, Beck F, Mallo M, Deschamps J
Dev Cell. 2009
PubMed ID: 19853565
Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain.
Zhu Y, Cuevas IC, Gabriel RA, Su H, Nishimura S, Gao P, Fields A, Hao Q, Young WL, Yang GY, Boudreau NJ
J Neuropathol Exp Neurol. 2009
PubMed ID: 19458547
A High-Density Association Study of 383 Candidate Genes for Volumetric Bone Density at the Femoral Neck and Lumbar Spine among Older Men.
Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, for the MrOS Research Group
J Bone Miner Res. 2009
PubMed ID: 19453261
Quantification of Hox and surfactant protein-B transcription during murine lung development.
Grier DG, Thompson A, Lappin TR, Halliday HL
Neonatology. 2009
PubMed ID: 19204410
Unique spatial and cellular expression patterns of Hoxa5, Hoxb4, and Hoxb6 proteins in normal developing murine lung are modified in pulmonary hypoplasia.
Volpe MV, Wang KT, Nielsen HC, Chinoy MR
Birth Defects Res A Clin Mol Teratol. 2008
PubMed ID: 18553509
Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.
Dasen JS, De Camilli A, Wang B, Tucker PW, Jessell TM
Cell. 2008
PubMed ID: 18662545
Clinical significance of promoter hypermethylation of RASSF1A, RARbeta2, BRCA1 and HOXA5 in breast cancers of Indian patients.
Bagadi SA, Prasad CP, Kaur J, Srivastava A, Prashad R, Gupta SD, Ralhan R
Life Sci. 2008
PubMed ID: 18538349
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.
Ha HY, Kim JB, Cho IH, Joo HJ, Kim KS, Lee KW, Sunwoo H, Im JY, Lee JK, Hong JH, Han PL
Proteomics. 2008
PubMed ID: 18324732
Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5.
Chen Y, Gorski DH
Blood. 2008
PubMed ID: 17957028
HoxA5 stabilizes adherens junctions via increased Akt1.
Arderiu G, Cuevas I, Chen A, Carrio M, East L, Boudreau NJ
Cell Adh Migr. 2007
PubMed ID: 19262140
HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition.
Chen H, Zhang H, Lee J, Liang X, Wu X, Zhu T, Lo PK, Zhang X, Sukumar S
Cancer Res. 2007
PubMed ID: 17804711
Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis.
Strathdee G, Holyoake TL, Sim A, Parker A, Oscier DG, Melo JV, Meyer S, Eden T, Dickinson AM, Mountford JC, Jorgensen HG, Soutar R, Brown R
Clin Cancer Res. 2007
PubMed ID: 17785556
Hox patterning of the vertebrate rib cage.
McIntyre DC, Rakshit S, Yallowitz AR, Loken L, Jeannotte L, Capecchi MR, Wellik DM
Development. 2007
PubMed ID: 17626057
Toward simpler and faster genome-wide mutagenesis in mice.
Wu S, Ying G, Wu Q, Capecchi MR
Nat Genet. 2007
PubMed ID: 17572674
Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis.
Ueda T, Watanabe-Fukunaga R, Ogawa H, Fukuyama H, Higashi Y, Nagata S, Fukunaga R
Genes Cells. 2007
PubMed ID: 17535249
Comparative analysis of Hoxa5 allelic series.
Tabariès S, Lemieux M, Aubin J, Jeannotte L
Genesis. 2007
PubMed ID: 17417799
Juxtaposed Polycomb complexes co-regulate vertebral identity.
Kim SY, Paylor SW, Magnuson T, Schumacher A
Development. 2006
PubMed ID: 17107999
Impact of the loss of Hoxa5 function on lung alveogenesis.
Mandeville I, Aubin J, LeBlanc M, Lalancette-Hébert M, Janelle MF, Tremblay GM, Jeannotte L
Am J Pathol. 2006
PubMed ID: 17003488
A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA
Development. 2006
PubMed ID: 16971476
Stromal Hoxa5 function controls the growth and differentiation of mammary alveolar epithelium.
Garin E, Lemieux M, Coulombe Y, Robinson GW, Jeannotte L
Dev Dyn. 2006
PubMed ID: 16607641
Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.
Terranova R, Agherbi H, Boned A, Meresse S, Djabali M
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16618927
HOXA5 regulates hMLH1 expression in breast cancer cells.
Duriseti S, Winnard PT, Mironchik Y, Vesuna F, Raman A, Raman V
Neoplasia. 2006
PubMed ID: 16756717
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Expression pattern of a homeotic gene, HOXA5, in normal breast and in breast tumors.
Henderson GS, van Diest PJ, Burger H, Russo J, Raman V
Cell Oncol. 2006
PubMed ID: 17167183
Ectopic HOXA5 expression results in abnormal differentiation, migration and p53-independent cell death of superficial dorsal horn neurons.
Abbott MA, Joksimovic M, Tuggle CK
Brain Res Dev Brain Res. 2005
PubMed ID: 16139370
Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1.
Ivins S, Lammerts van Beuren K, Roberts C, James C, Lindsay E, Baldini A, Ataliotis P, Scambler PJ
Dev Biol. 2005
PubMed ID: 16109395
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.
Isono K, Fujimura Y, Shinga J, Yamaki M, O-Wang J, Takihara Y, Murahashi Y, Takada Y, Mizutani-Koseki Y, Koseki H
Mol Cell Biol. 2005
PubMed ID: 16024804
Dynamic expression of murine HOXA5 protein in the central nervous system.
Joksimovic M, Jeannotte L, Tuggle CK
Gene Expr Patterns. 2005
PubMed ID: 15922675
Identification of transcriptional targets of HOXA5.
Chen H, Rubin E, Zhang H, Chung S, Jie CC, Garrett E, Biswal S, Sukumar S
J Biol Chem. 2005
PubMed ID: 15757903
Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1.
Isono K, Mizutani-Koseki Y, Komori T, Schmidt-Zachmann MS, Koseki H
Genes Dev. 2005
PubMed ID: 15741318
Cdx protein interaction with Hoxa5 regulatory sequences contributes to Hoxa5 regional expression along the axial skeleton.
Tabariès S, Lapointe J, Besch T, Carter M, Woollard J, Tuggle CK, Jeannotte L
Mol Cell Biol. 2005
PubMed ID: 15684390
Genomic maps and comparative analysis of histone modifications in human and mouse.
Bernstein BE, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey DK, Huebert DJ, McMahon S, Karlsson EK, Kulbokas EJ, Gingeras TR, Schreiber SL, Lander ES
Cell. 2005
PubMed ID: 15680324
HOXA5-twist interaction alters p53 homeostasis in breast cancer cells.
Stasinopoulos IA, Mironchik Y, Raman A, Wildes F, Winnard P, Raman V
J Biol Chem. 2005
PubMed ID: 15545268
Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
Williams TM, Williams ME, Innis JW
Dev Biol. 2005
PubMed ID: 15617687
A role for Hox A5 in regulating angiogenesis and vascular patterning.
Rhoads K, Arderiu G, Charboneau A, Hansen SL, Hoffman W, Boudreau N
Lymphat Res Biol. 2005
PubMed ID: 16379594
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Respiratory adaptations to lung morphological defects in adult mice lacking Hoxa5 gene function.
Kinkead R, LeBlanc M, Gulemetova R, Lalancette-Hébert M, Lemieux M, Mandeville I, Jeannotte L
Pediatr Res. 2004
PubMed ID: 15295088
Increased DNA methylation in the HoxA5 promoter region correlates with decreased expression of the gene during tumor promotion.
Watson RE, Curtin GM, Hellmann GM, Doolittle DJ, Goodman JI
Mol Carcinog. 2004
PubMed ID: 15352125
Transgenic mice ectopically expressing HOXA5 in the dorsal spinal cord show structural defects of the cervical spinal cord along with sensory and motor defects of the forelimb.
Krieger KE, Abbott MA, Joksimovic M, Lueth PA, Sonea IM, Jeannotte L, Tuggle CK
Brain Res Dev Brain Res. 2004
PubMed ID: 15158076
Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation.
Villaescusa JC, Verrotti AC, Ferretti E, Farookhi R, Blasi F
Gene. 2004
PubMed ID: 15087118
Atlas of Hox gene expression in the developing kidney.
Patterson LT, Potter SS
Dev Dyn. 2004
PubMed ID: 15042701
HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8.
Chen H, Chung S, Sukumar S
Mol Cell Biol. 2004
PubMed ID: 14701762
Genetic architecture of the mouse hippocampus: identification of gene loci with selective regional effects.
Peirce JL, Chesler EJ, Williams RW, Lu L
Genes Brain Behav. 2003
PubMed ID: 12953790
The DNA sequence of human chromosome 7.
Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S, Rohlfing T, Rock SM, Tin-Wollam AM, Abbott A, Minx P, Maupin R, Strowmatt C, Latreille P, Miller N, Johnson D, Murray J, Woessner JP, Wendl MC, Yang SP, Schultz BR, Wallis JW, Spieth J, Bieri TA, Nelson JO, Berkowicz N, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Bedell JA, Mardis ER, Clifton SW, Chissoe SL, Marra MA, Raymond C, Haugen E, Gillett W, Zhou Y, James R, Phelps K, Iadanoto S, Bubb K, Simms E, Levy R, Clendenning J, Kaul R, Kent WJ, Furey TS, Baertsch RA, Brent MR, Keibler E, Flicek P, Bork P, Suyama M, Bailey JA, Portnoy ME, Torrents D, Chinwalla AT, Gish WR, Eddy SR, McPherson JD, Olson MV, Eichler EE, Green ED, Waterston RH, Wilson RK
Nature. 2003
PubMed ID: 12853948
Perturbed thyroid morphology and transient hypothyroidism symptoms in Hoxa5 mutant mice.
Meunier D, Aubin J, Jeannotte L
Dev Dyn. 2003
PubMed ID: 12815622
Human chromosome 7: DNA sequence and biology.
Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Lai Z, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Nowaczyk MJ, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Döhner H, Döhner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui LC
Science. 2003
PubMed ID: 12690205
Joint regulation of the MAP1B promoter by HNF3beta/Foxa2 and Engrailed is the result of a highly conserved mechanism for direct interaction of homeoproteins and Fox transcription factors.
Foucher I, Montesinos ML, Volovitch M, Prochiantz A, Trembleau A
Development. 2003
PubMed ID: 12642491
Methylation of HoxA5 and HoxB5 and its relevance to expression during mouse development.
Hershko AY, Kafri T, Fainsod A, Razin A
Gene. 2003
PubMed ID: 12527197
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.
Wang J, Mager J, Schnedier E, Magnuson T
Mamm Genome. 2002
PubMed ID: 12370779
Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling.
Aubin J, Déry U, Lemieux M, Chailler P, Jeannotte L
Development. 2002
PubMed ID: 12163410
Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors.
Foucher I, Volovitch M, Frain M, Kim JJ, Souberbielle JC, Gan L, Unterman TG, Prochiantz A, Trembleau A
Development. 2002
PubMed ID: 12163409
Cooperation of Hoxa5 and Pax1 genes during formation of the pectoral girdle.
Aubin J, Lemieux M, Moreau J, Lapointe J, Jeannotte L
Dev Biol. 2002
PubMed ID: 11900462
Region-specific gastrointestinal Hox code during murine embryonal gut development.
Kawazoe Y, Sekimoto T, Araki M, Takagi K, Araki K, Yamamura K
Dev Growth Differ. 2002
PubMed ID: 11869294
Complete mutation analysis panel of the 39 human HOX genes.
Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, Tomita M, McGinnis W, Matsuo N
Teratology. 2002
PubMed ID: 11857506
HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema.
Golpon HA, Geraci MW, Moore MD, Miller HL, Miller GJ, Tuder RM, Voelkel NF
Am J Pathol. 2001
PubMed ID: 11238043
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Hoxa-5 in mouse developing lung: cell-specific expression and retinoic acid regulation.
Kim C, Nielsen HC
Am J Physiol Lung Cell Mol Physiol. 2000
PubMed ID: 11053021
Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG
Mech Dev. 2000
PubMed ID: 11044609
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
HOXA5 regulates expression of the progesterone receptor.
Raman V, Tamori A, Vali M, Zeller K, Korz D, Sukumar S
J Biol Chem. 2000
PubMed ID: 10875927
Compromised HOXA5 function can limit p53 expression in human breast tumours.
Raman V, Martensen SA, Reisman D, Evron E, Odenwald WF, Jaffee E, Marks J, Sukumar S
Nature. 2000
PubMed ID: 10879542
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.
Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10737800
Stage-specific homeotic vertebral transformations in mouse fetuses induced by maternal hyperthermia during somitogenesis.
Li ZL, Shiota K
Dev Dyn. 1999
PubMed ID: 10633854
Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code.
Pitera JE, Smith VV, Thorogood P, Milla PJ
Gastroenterology. 1999
PubMed ID: 10579975
Loss of Hoxa5 gene function in mice perturbs intestinal maturation.
Aubin J, Chailler P, Ménard D, Jeannotte L
Am J Physiol. 1999
PubMed ID: 10564089
Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors.
Crooks GM, Fuller J, Petersen D, Izadi P, Malik P, Pattengale PK, Kohn DB, Gasson JC
Blood. 1999
PubMed ID: 10397719
Hoxa5 gene regulation: A gradient of binding activity to a brachial spinal cord element.
Nowling T, Zhou W, Krieger KE, Larochelle C, Nguyen-Huu MC, Jeannotte L, Tuggle CK
Dev Biol. 1999
PubMed ID: 10075847
Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression.
Larochelle C, Tremblay M, Bernier D, Aubin J, Jeannotte L
Dev Dyn. 1999
PubMed ID: 10030592
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Transcriptional interferences at the Hoxa4/Hoxa5 locus: importance of correct Hoxa5 expression for the proper specification of the axial skeleton.
Aubin J, Lemieux M, Tremblay M, Behringer RR, Jeannotte L
Dev Dyn. 1998
PubMed ID: 9603431
HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development.
Stelnicki EJ, Kömüves LG, Kwong AO, Holmes D, Klein P, Rozenfeld S, Lawrence HJ, Adzick NS, Harrison M, Largman C
J Invest Dermatol. 1998
PubMed ID: 9457903
Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects.
Aubin J, Lemieux M, Tremblay M, Bérard J, Jeannotte L
Dev Biol. 1997
PubMed ID: 9441679
Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung.
Mollard R, Dziadek M
Int J Dev Biol. 1997
PubMed ID: 9415485
Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.
Takihara Y, Tomotsune D, Shirai M, Katoh-Fukui Y, Nishii K, Motaleb MA, Nomura M, Tsuchiya R, Fujita Y, Shibata Y, Higashinakagawa T, Shimada K
Development. 1997
PubMed ID: 9367423
Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice.
Coré N, Bel S, Gaunt SJ, Aurrand-Lions M, Pearce J, Fisher A, Djabali M
Development. 1997
PubMed ID: 9043087
The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.
van der Lugt NM, Alkema M, Berns A, Deschamps J
Mech Dev. 1996
PubMed ID: 8887324
A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton.
Akasaka T, Kanno M, Balling R, Mieza MA, Taniguchi M, Koseki H
Development. 1996
PubMed ID: 8625838
Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex.
Lu Q, Kamps MP
Mol Cell Biol. 1996
PubMed ID: 8657138
Functional dissection of the mouse Hox-a5 gene.
Zhao JJ, Lazzarini RA, Pick L
EMBO J. 1996
PubMed ID: 8635464
Orientation of the Hoxa complex and placement of the Hd locus distal to Hoxa2 on mouse chromosome 6.
Innis JW, Darling SM, Kazen-Gillespie K, Post LC, Mortlock DP, Yang T
Mamm Genome. 1996
PubMed ID: 8833244
Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells.
Miano JM, Firulli AB, Olson EN, Hara P, Giachelli CM, Schwartz SM
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8570656
Fine mapping of human HOX gene clusters.
Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B
Cytogenet Cell Genet. 1996
PubMed ID: 8646877
Activation of Hox gene expression by Hoxa-5.
Lobe CG
DNA Cell Biol. 1995
PubMed ID: 7546287
A duplicated zone of polarizing activity in polydactylous mouse mutants.
Masuya H, Sagai T, Wakana S, Moriwaki K, Shiroishi T
Genes Dev. 1995
PubMed ID: 7628698
Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster.
Pellerin I, Schnabel C, Catron KM, Abate C
Mol Cell Biol. 1994
PubMed ID: 7911971
Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column.
Kostic D, Capecchi MR
Mech Dev. 1994
PubMed ID: 7918106
Cloning and sequence analysis of homeobox transcription factor cDNAs with an inosine-containing probe.
Gorski DH, LePage DF, Walsh K
Biotechniques. 1994
PubMed ID: 7915120
Identification of Hox genes in newborn lung and effects of gestational age and retinoic acid on their expression.
Bogue CW, Gross I, Vasavada H, Dynia DW, Wilson CM, Jacobs HC
Am J Physiol. 1994
PubMed ID: 7909996
Identification and promoter activity of DNase I hypersensitive sites in the region of the Hox-1.3 gene.
Lobe CG, Gruss P
DNA Cell Biol. 1994
PubMed ID: 7910023
Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.
Jeannotte L, Lemieux M, Charron J, Poirier F, Robertson EJ
Genes Dev. 1993
PubMed ID: 7901120
GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function.
Godfrey P, Rahal JO, Beamer WG, Copeland NG, Jenkins NA, Mayo KE
Nat Genet. 1993
PubMed ID: 8395283
Organization and expression of mouse Hox3 cluster genes.
Goto J, Miyabayashi T, Wakamatsu Y, Takahashi N, Muramatsu M
Mol Gen Genet. 1993
PubMed ID: 8099712
The short 3'-end region of complementary DNAs as PCR-based polymorphic markers for an expression map of the mouse genome.
Takahashi N, Ko MS
Genomics. 1993
PubMed ID: 8486351
The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene.
Zhao JJ, Lazzarini RA, Pick L
Genes Dev. 1993
PubMed ID: 8095481
Conservation and divergence of patterns of expression and lineage-specific transcripts in orthologues and paralogues of the mouse Hox-1.4 gene.
Watrin F, Wolgemuth DJ
Dev Biol. 1993
PubMed ID: 7680626
Vertebrate homeobox gene nomenclature.
Scott MP
Cell. 1992
PubMed ID: 1358459
Hox-1.11 and Hox-4.9 homeobox genes.
Nazarali A, Kim Y, Nirenberg M
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1348361
Chromosomal localization of three pulmonary surfactant protein genes in the mouse.
Moore KJ, D'Amore-Bruno MA, Korfhagen TR, Glasser SW, Whitsett JA, Jenkins NA, Copeland NG
Genomics. 1992
PubMed ID: 1346779
Identification of 10 murine homeobox genes.
Singh G, Kaur S, Stock JL, Jenkins NA, Gilbert DJ, Copeland NG, Potter SS
Proc Natl Acad Sci U S A. 1991
PubMed ID: 1683707
Low level of Hox1.3 gene expression does not preclude the use of promoterless vectors to generate a targeted gene disruption. off.
Jeannotte L, Ruiz JC, Robertson EJ
Mol Cell Biol. 1991
PubMed ID: 1717831
Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.
Siracusa LD, Rosner MH, Vigano MA, Gilbert DJ, Staudt LM, Copeland NG, Jenkins NA
Genomics. 1991
PubMed ID: 1676977
Nomenclature for human homeobox genes.
McAlpine PJ, Shows TB
Genomics. 1990
PubMed ID: 1973146
Mouse Hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the Hox gene network.
Gaunt SJ, Coletta PL, Pravtcheva D, Sharpe PT
Development. 1990
PubMed ID: 1976088
Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome.
Dressler GR, Gruss P
Differentiation. 1989
PubMed ID: 2575552
Remarkable intron and exon sequence conservation in human and mouse homeobox Hox 1.3 genes.
Tournier-Lasserve E, Odenwald WF, Garbern J, Trojanowski J, Lazzarini RA
Mol Cell Biol. 1989
PubMed ID: 2568583
Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development.
Wolgemuth DJ, Behringer RR, Mostoller MP, Brinster RL, Palmiter RD
Nature. 1989
PubMed ID: 2563568
The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein.
Odenwald WF, Garbern J, Arnheiter H, Tournier-Lasserve E, Lazzarini RA
Genes Dev. 1989
PubMed ID: 2565857
Organization of human class I homeobox genes.
Boncinelli E, Acampora D, Pannese M, D'Esposito M, Somma R, Gaudino G, Stornaiuolo A, Cafiero M, Faiella A, Simeone A
Genome. 1989
PubMed ID: 2576652
Coding sequence and expression of the homeobox gene Hox 1.3.
Fibi M, Zink B, Kessel M, Colberg-Poley AM, Labeit S, Lehrach H, Gruss P
Development. 1988
PubMed ID: 2901335
Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex.
Baron A, Featherstone MS, Hill RE, Hall A, Galliot B, Duboule D
EMBO J. 1987
PubMed ID: 2891503
Expression of a homeo domain protein in noncontact-inhibited cultured cells and postmitotic neurons.
Odenwald WF, Taylor CF, Palmer-Hill FJ, Friedrich V, Tani M, Lazzarini RA
Genes Dev. 1987
PubMed ID: 2890554
A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus.
Duboule D, Baron A, Mähl P, Galliot B
EMBO J. 1986
PubMed ID: 3019676
Clustered homeo boxes are differentially expressed during murine development.
Colberg-Poley AM, Voss SD, Chowdhury K, Stewart CL, Wagner EF, Gruss P
Cell. 1985
PubMed ID: 2416462

Model Organism Phenotype Links Top Help

This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.

Organism	Phenotype	Resources
Mouse	MGI:96177	IKMC

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	3202	15402	79241
EnsEMBL Gene(s)	ENSG00000106004	ENSMUSG00000038253	N/A
Unigene	Hs.655218	Mm.173	Rn.8465
Homologene	HOXA5	Hoxa5	Hoxa5
OMIM	142952	N/A	N/A
GeneCards	HOXA5	N/A	N/A
Beta Cell Genomics	DT.213953	DT.40186269	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
MGI	N/A	MGI:96177	N/A
WikiGenes	3202	15402	79241

External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network Top Help

Relevant resources:

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