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HOXA1

Gene Description:   homeo box A1; homeobox A1 Synonyms:   HOX1, ERA1, Hox-1.6, Hoxa1, BSAS, HOX1F, HOXA1, MGC45232 Orthologs:   Human HOXA1 (protein-coding), Mouse Hoxa1 (protein-coding), Rat Hoxa1 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Human-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1 Rat: 2

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
7p15.2	Human	chr7:26657962..27205282	0.55	75	rs7804356

Other Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm14	Rat	chr4:63276741..160891592	97.61	829
Human 7p15.2 Orthologous Region	Mouse	chr6:51768205..52199869	0.43	14
Human 7p15.2 Orthologous Region	Rat	chr4:80112734..80552452	0.44	10

(Human) GRCh37 - chr7:27132612..27135625 (31 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr6:52105366..52108316 (2.95 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr4:80456728..80458388 (1.66 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for HOXA1: The HOXA1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs HOXA1   KDM5B   BioGRID  empirical  19336002  HOXA1   CHIC2   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   GRN   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   CERS2   BioGRID  empirical  20211142  HOXA1   EFEMP2   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   MDFI   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   PAX9   BioGRID  empirical  20211142  HOXA1   PBX1   BioGRID  empirical  20211142  HOXA1   PKNOX1   BioGRID  empirical  9582372  HOXA1   PLSCR1   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   PRNP   IntAct  empirical  18482256  HOXA1   TCF3   HPRD  empirical  9582372  HOXA1   TRIP6   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   TRAPPC6A   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   KRTAP4-12   HPRD, MINT, IntAct, BioGRID  empirical  16189514  HOXA1   LPXN   HPRD, MINT, IntAct, BioGRID  empirical  16189514

View all

KEGG Network: None available   None available.

Biocarta: None available   None available.

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 31   Sequence-specific DNA binding transcription factor activity GO:0003700 Protein binding GO:0005515 Nucleus GO:0005634 Multicellular organismal development GO:0007275 Nervous system development GO:0007399 Sensory perception of sound GO:0007605 Optokinetic behavior GO:0007634 Motor axon guidance GO:0008045 Anatomical structure morphogenesis GO:0009653 Anterior/posterior pattern specification GO:0009952 Rhombomere 3 development GO:0021569 Rhombomere 4 development GO:0021570 Rhombomere 5 development GO:0021571 Abducens nerve formation GO:0021599 Facial nerve structural organization GO:0021612 Facial nucleus development GO:0021754 Central nervous system neuron differentiation GO:0021953 Hindbrain development GO:0030902 Outer ear morphogenesis GO:0042473 Sequence-specific DNA binding GO:0043565 Positive regulation of transcription from RNA polymerase II promoter GO:0045944 Embryonic neurocranium morphogenesis GO:0048702 Inner ear development GO:0048839 Artery morphogenesis GO:0048844 Regulation of behavior GO:0050795 Cognition GO:0050890 Neuromuscular process GO:0050905 Artery development GO:0060840 Semicircular canal formation GO:0060876 Cochlea development GO:0090102 Cochlea morphogenesis GO:0090103

	KEGG Network: None available
	Biocarta: None available
	Reactome: None available
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 31 Sequence-specific DNA binding transcription factor activity GO:0003700 Protein binding GO:0005515 Nucleus GO:0005634 Multicellular organismal development GO:0007275 Nervous system development GO:0007399 Sensory perception of sound GO:0007605 Optokinetic behavior GO:0007634 Motor axon guidance GO:0008045 Anatomical structure morphogenesis GO:0009653 Anterior/posterior pattern specification GO:0009952 Rhombomere 3 development GO:0021569 Rhombomere 4 development GO:0021570 Rhombomere 5 development GO:0021571 Abducens nerve formation GO:0021599 Facial nerve structural organization GO:0021612 Facial nucleus development GO:0021754 Central nervous system neuron differentiation GO:0021953 Hindbrain development GO:0030902 Outer ear morphogenesis GO:0042473 Sequence-specific DNA binding GO:0043565 Positive regulation of transcription from RNA polymerase II promoter GO:0045944 Embryonic neurocranium morphogenesis GO:0048702 Inner ear development GO:0048839 Artery morphogenesis GO:0048844 Regulation of behavior GO:0050795 Cognition GO:0050890 Neuromuscular process GO:0050905 Artery development GO:0060840 Semicircular canal formation GO:0060876 Cochlea development GO:0090102 Cochlea morphogenesis GO:0090103

Publications: 148

• Plasticity of neural crest-placode interaction in the developing visceral nervous system.
  Chen Y, Takano-Maruyama M, Gaufo GO
  Dev Dyn. 2011
  PubMed ID: 21674689
   
  
• Hox genes define distinct progenitor sub-domains within the second heart field.
  Bertrand N, Roux M, Ryckebüsch L, Niederreither K, Dollé P, Moon A, Capecchi M, Zaffran S
  Dev Biol. 2011
  PubMed ID: 21385575
   
  
• Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation.
  Vitobello A, Ferretti E, Lampe X, Vilain N, Ducret S, Ori M, Spetz JF, Selleri L, Rijli FM
  Dev Cell. 2011
  PubMed ID: 21497760
   
  
• Regulation of heme oxygenase-1 protein expression by miR-377 in combination with miR-217.
  Beckman JD, Chen C, Nguyen J, Thayanithy V, Subramanian S, Steer CJ, Vercellotti GM
  J Biol Chem. 2011
  PubMed ID: 21106538
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
  Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL
  Gene Expr Patterns. 2011
  PubMed ID: 20932939
   
  
• Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere.
  Makki N, Capecchi MR
  Dev Biol. 2010
  PubMed ID: 20171203
   
  
• SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.
  Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET
  Mol Cell. 2010
  PubMed ID: 20417598
   
  
• An atlas of combinatorial transcriptional regulation in mouse and man.
  Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
  Cell. 2010
  PubMed ID: 20211142
   
  
• HOXA1 mutations are not a common cause of Möbius syndrome.
  Rankin JK, Andrews C, Chan WM, Engle EC
  J AAPOS. 2010
  PubMed ID: 20227628
   
  
• Candidate gene study of HOXB1 in autism spectrum disorder.
  Muscarella LA, Guarnieri V, Sacco R, Curatolo P, Manzi B, Alessandrelli R, Giana G, Militerni R, Bravaccio C, Lenti C, Saccani M, Schneider C, Melmed R, D'Agruma L, Persico AM
  Mol Autism. 2010
  PubMed ID: 20678259
   
  
• Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals.
  Lomberk GA, Imoto I, Gebelein B, Urrutia R, Cook TA
  Pancreatology. 2010
  PubMed ID: 20339309
   
  
• A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
  Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
  Dev Cell. 2009
  PubMed ID: 20059953
   
  
• Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity.
  Voss AK, Collin C, Dixon MP, Thomas T
  Dev Cell. 2009
  PubMed ID: 19922872
   
  
• Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome.
  Chakrabarti B, Dudbridge F, Kent L, Wheelwright S, Hill-Cawthorne G, Allison C, Banerjee-Basu S, Baron-Cohen S
  Autism Res. 2009
  PubMed ID: 19598235
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.
  Zhou W, Chen H, Zhang L
  BMB Rep. 2009
  PubMed ID: 19336002
   
  
• Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation.
  Wang LL, Zhang Z, Li Q, Yang R, Pei X, Xu Y, Wang J, Zhou SF, Li Y
  Hum Reprod. 2009
  PubMed ID: 19091803
   
  
• The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells.
  Fernandez CC, Gudas LJ
  J Cell Biochem. 2009
  PubMed ID: 19115252
   
  
• Protein microarray analysis identifies human cellular prion protein interactors.
  Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H
  Neuropathol Appl Neurobiol. 2009
  PubMed ID: 18482256
   
  
• Quantification of Hox and surfactant protein-B transcription during murine lung development.
  Grier DG, Thompson A, Lappin TR, Halliday HL
  Neonatology. 2009
  PubMed ID: 19204410
   
  
• Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
  Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, The Psychiatric Genetics Network GroupComplete list of members appeared as Supplementary Note.
  Am J Med Genet B Neuropsychiatr Genet. 2008
  PubMed ID: 19086053
   
  
• Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders.
  Laroche F, Ramoz N, Leroy S, Fortin C, Rousselot-Paillet B, Philippe A, Colleaux L, Bresson JL, Mogenet A, Golse B, Mouren-Simeoni MC, Gorwood P, Galli T, Simonneau M, Krebs MO, Robel L
  Psychiatr Genet. 2008
  PubMed ID: 19018235
   
  
• HOXA1 A218G Polymorphism is Associated with Smaller Cerebellar Volume in Healthy Humans.
  Canu E, Boccardi M, Ghidoni R, Benussi L, Duchesne S, Testa C, Binetti G, Frisoni GB
  J Neuroimaging. 2008
  PubMed ID: 19018953
   
  
• Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.
  Wassef MA, Chomette D, Pouilhe M, Stedman A, Havis E, Desmarquet-Trin Dinh C, Schneider-Maunoury S, Gilardi-Hebenstreit P, Charnay P, Ghislain J
  Development. 2008
  PubMed ID: 18787068
   
  
• Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons.
  Martinez-Ceballos E, Gudas LJ
  J Neurosci Res. 2008
  PubMed ID: 18512762
   
  
• The clinical spectrum of homozygous HOXA1 mutations.
  Bosley TM, Alorainy IA, Salih MA, Aldhalaan HM, Abu-Amero KK, Oystreck DT, Tischfield MA, Engle EC, Erickson RP
  Am J Med Genet A. 2008
  PubMed ID: 18412118
   
  
• Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell.
  Mohankumar KM, Perry JK, Kannan N, Kohno K, Gluckman PD, Emerald BS, Lobie PE
  Endocrinology. 2008
  PubMed ID: 18276758
   
  
• GUDMAP: the genitourinary developmental molecular anatomy project.
  McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
  J Am Soc Nephrol. 2008
  PubMed ID: 18287559
   
  
• Retinoic acid deficiency alters second heart field formation.
  Ryckebusch L, Wang Z, Bertrand N, Lin SC, Chi X, Schwartz R, Zaffran S, Niederreither K
  Proc Natl Acad Sci U S A. 2008
  PubMed ID: 18287057
   
  
• Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
  Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H
  BMC Genomics. 2008
  PubMed ID: 18973680
   
  
• Clinical characterization of the HOXA1 syndrome BSAS variant.
  Bosley TM, Salih MA, Alorainy IA, Oystreck DT, Nester M, Abu-Amero KK, Tischfield MA, Engle EC
  Neurology. 2007
  PubMed ID: 17875913
   
  
• Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis.
  Rinon A, Lazar S, Marshall H, Büchmann-Møller S, Neufeld A, Elhanany-Tamir H, Taketo MM, Sommer L, Krumlauf R, Tzahor E
  Development. 2007
  PubMed ID: 17652354
   
  
• HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells.
  Mohankumar KM, Xu XQ, Zhu T, Kannan N, Miller LD, Liu ET, Gluckman PD, Sukumar S, Emerald BS, Lobie PE
  Oncogene. 2007
  PubMed ID: 17213808
   
  
• HOXA1 gene variants influence head growth rates in humans.
  Muscarella LA, Guarnieri V, Sacco R, Militerni R, Bravaccio C, Trillo S, Schneider C, Melmed R, Elia M, Mascia ML, Rucci E, Piemontese MR, D'Agruma L, Persico AM
  Am J Med Genet B Neuropsychiatr Genet. 2007
  PubMed ID: 17171652
   
  
• Enhanced autophagic cell death in expanded polyhistidine variants of HOXA1 reduces PBX1-coupled transcriptional activity and inhibits neuronal differentiation.
  Paraguison RC, Higaki K, Yamamoto K, Matsumoto H, Sasaki T, Kato N, Nanba E
  J Neurosci Res. 2007
  PubMed ID: 17131398
   
  
• Lack of association of HOXA1 and HOXB1 variants with autism in the Indian population.
  Sen B, Sinha S, Ahmed S, Ghosh S, Gangopadhyay PK, Usha R
  Psychiatr Genet. 2007
  PubMed ID: 17167333
   
  
• Yeast two-hybrid interaction partner screening through in vivo Cre-mediated Binary Interaction Tag generation.
  Hastie AR, Pruitt SC
  Nucleic Acids Res. 2007
  PubMed ID: 17986461
   
  
• Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma.
  Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen JA, Koss MN, Laird-Offringa IA
  Mol Cancer. 2007
  PubMed ID: 17967182
   
  
• Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.
  Dorrance AM, Liu S, Yuan W, Becknell B, Arnoczky KJ, Guimond M, Strout MP, Feng L, Nakamura T, Yu L, Rush LJ, Weinstein M, Leone G, Wu L, Ferketich A, Whitman SP, Marcucci G, Caligiuri MA
  J Clin Invest. 2006
  PubMed ID: 16981007
   
  
• A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
  Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA
  Development. 2006
  PubMed ID: 16971476
   
  
• Cloning of vertebrate Protogenin (Prtg) and comparative expression analysis during axis elongation.
  Vesque C, Anselme I, Couvé E, Charnay P, Schneider-Maunoury S
  Dev Dyn. 2006
  PubMed ID: 16881056
   
  
• Reversal of Hox1 gene subfunctionalization in the mouse.
  Tvrdik P, Capecchi MR
  Dev Cell. 2006
  PubMed ID: 16890163
   
  
• cDNA cloning and expression of the human NOBOX gene in oocytes and ovarian follicles.
  Huntriss J, Hinkins M, Picton HM
  Mol Hum Reprod. 2006
  PubMed ID: 16597639
   
  
• HOXA1 mutations are not a common cause of Duane anomaly.
  Tischfield MA, Chan WM, Grunert JF, Andrews C, Engle EC
  Am J Med Genet A. 2006
  PubMed ID: 16528738
   
  
• BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
  Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
  PLoS Biol. 2006
  PubMed ID: 16602821
   
  
• HOXA1 is required for E-cadherin-dependent anchorage-independent survival of human mammary carcinoma cells.
  Zhang X, Emerald BS, Mukhina S, Mohankumar KM, Kraemer A, Yap AS, Gluckman PD, Lee KO, Lobie PE
  J Biol Chem. 2006
  PubMed ID: 16373333
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• Polyhistidine tract expansions in HOXA1 result in intranuclear aggregation and increased cell death.
  Paraguison RC, Higaki K, Sakamoto Y, Hashimoto O, Miyake N, Matsumoto H, Yamamoto K, Sasaki T, Kato N, Nanba E
  Biochem Biophys Res Commun. 2005
  PubMed ID: 16168961
   
  
• Towards a proteome-scale map of the human protein-protein interaction network.
  Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M
  Nature. 2005
  PubMed ID: 16189514
   
  
• Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development.
  Tischfield MA, Bosley TM, Salih MA, Alorainy IA, Sener EC, Nester MJ, Oystreck DT, Chan WM, Andrews C, Erickson RP, Engle EC
  Nat Genet. 2005
  PubMed ID: 16155570
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
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• The transcriptional landscape of the mammalian genome.
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  Science. 2005
  PubMed ID: 16141072
   
  
• Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development.
  Matt N, Schmidt CK, Dupé V, Dennefeld C, Nau H, Chambon P, Mark M, Ghyselinck NB
  Dev Dyn. 2005
  PubMed ID: 15765518
   
  
• Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.
  Martinez-Ceballos E, Chambon P, Gudas LJ
  J Biol Chem. 2005
  PubMed ID: 15722554
   
  
• Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception.
  Warnecke M, Oster H, Revelli JP, Alvarez-Bolado G, Eichele G
  Genes Dev. 2005
  PubMed ID: 15741322
   
  
• Genomic maps and comparative analysis of histone modifications in human and mouse.
  Bernstein BE, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey DK, Huebert DJ, McMahon S, Karlsson EK, Kulbokas EJ, Gingeras TR, Schreiber SL, Lander ES
  Cell. 2005
  PubMed ID: 15680324
   
  
• Mouse brain organization revealed through direct genome-scale TF expression analysis.
  Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
  Science. 2004
  PubMed ID: 15618518
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Hox/Pbx and Brn binding sites mediate Pax3 expression in vitro and in vivo.
  Pruitt SC, Bussman A, Maslov AY, Natoli TA, Heinaman R
  Gene Expr Patterns. 2004
  PubMed ID: 15465489
   
  
• Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo.
  Remacle S, Abbas L, De Backer O, Pacico N, Gavalas A, Gofflot F, Picard JJ, Rezsöhazy R
  Mol Cell Biol. 2004
  PubMed ID: 15367676
   
  
• High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
  Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
  Genome Res. 2004
  PubMed ID: 15060019
   
  
• Atlas of Hox gene expression in the developing kidney.
  Patterson LT, Potter SS
  Dev Dyn. 2004
  PubMed ID: 15042701
   
  
• Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism.
  Conciatori M, Stodgell CJ, Hyman SL, O'Bara M, Militerni R, Bravaccio C, Trillo S, Montecchi F, Schneider C, Melmed R, Elia M, Crawford L, Spence SJ, Muscarella L, Guarnieri V, D'Agruma L, Quattrone A, Zelante L, Rabinowitz D, Pascucci T, Puglisi-Allegra S, Reichelt KL, Rodier PM, Persico AM
  Biol Psychiatry. 2004
  PubMed ID: 14960295
   
  
• Complete sequencing and characterization of 21,243 full-length human cDNAs.
  Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
  Nat Genet. 2004
  PubMed ID: 14702039
   
  
• Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes.
  Gavalas A, Ruhrberg C, Livet J, Henderson CE, Krumlauf R
  Development. 2003
  PubMed ID: 14522873
   
  
• The DNA sequence of human chromosome 7.
  Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S, Rohlfing T, Rock SM, Tin-Wollam AM, Abbott A, Minx P, Maupin R, Strowmatt C, Latreille P, Miller N, Johnson D, Murray J, Woessner JP, Wendl MC, Yang SP, Schultz BR, Wallis JW, Spieth J, Bieri TA, Nelson JO, Berkowicz N, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Bedell JA, Mardis ER, Clifton SW, Chissoe SL, Marra MA, Raymond C, Haugen E, Gillett W, Zhou Y, James R, Phelps K, Iadanoto S, Bubb K, Simms E, Levy R, Clendenning J, Kaul R, Kent WJ, Furey TS, Baertsch RA, Brent MR, Keibler E, Flicek P, Bork P, Suyama M, Bailey JA, Portnoy ME, Torrents D, Chinwalla AT, Gish WR, Eddy SR, McPherson JD, Olson MV, Eichler EE, Green ED, Waterston RH, Wilson RK
  Nature. 2003
  PubMed ID: 12853948
   
  
• NSD1 is essential for early post-implantation development and has a catalytically active SET domain.
  Rayasam GV, Wendling O, Angrand PO, Mark M, Niederreither K, Song L, Lerouge T, Hager GL, Chambon P, Losson R
  EMBO J. 2003
  PubMed ID: 12805229
   
  
• The HOXA1 A218G polymorphism and autism: lack of association in white and black patients from the South Carolina Autism Project.
  Collins JS, Schroer RJ, Bird J, Michaelis RC
  J Autism Dev Disord. 2003
  PubMed ID: 12908836
   
  
• The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system.
  Niederreither K, Vermot J, Le Roux I, Schuhbaur B, Chambon P, Dollé P
  Development. 2003
  PubMed ID: 12702665
   
  
• Human chromosome 7: DNA sequence and biology.
  Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Lai Z, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Nowaczyk MJ, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Döhner H, Döhner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui LC
  Science. 2003
  PubMed ID: 12690205
   
  
• Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene.
  Zhang X, Zhu T, Chen Y, Mertani HC, Lee KO, Lobie PE
  J Biol Chem. 2003
  PubMed ID: 12482855
   
  
• Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice.
  Vermot J, Niederreither K, Garnier JM, Chambon P, Dollé P
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 12563036
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• Targeted insertion results in a rhombomere 2-specific Hoxa2 knockdown and ectopic activation of Hoxa1 expression.
  Ren SY, Angrand PO, Rijli FM
  Dev Dyn. 2002
  PubMed ID: 12412013
   
  
• No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA network.
  Devlin B, Bennett P, Cook EH, Dawson G, Gonen D, Grigorenko EL, McMahon W, Pauls D, Smith M, Spence MA, Schellenberg GD, Collaborative Programs of Excellence in Autism (CPEA) Genetics Network
  Am J Med Genet. 2002
  PubMed ID: 12210285
   
  
• A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.
  Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD
  Science. 2002
  PubMed ID: 12040188
   
  
• Complete mutation analysis panel of the 39 human HOX genes.
  Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, Tomita M, McGinnis W, Matsuo N
  Teratology. 2002
  PubMed ID: 11857506
   
  
• Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families.
  Li J, Tabor HK, Nguyen L, Gleason C, Lotspeich LJ, Spiker D, Risch N, Myers RM
  Am J Med Genet. 2002
  PubMed ID: 11840501
   
  
• Converging evidence for brain stem injury in autism.
  Rodier PM
  Dev Psychopathol. 2002
  PubMed ID: 12349873
   
  
• Retinoic acid rescues inner ear defects in Hoxa1 deficient mice.
  Pasqualetti M, Neun R, Davenne M, Rijli FM
  Nat Genet. 2001
  PubMed ID: 11528388
   
  
• Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest.
  Gavalas A, Trainor P, Ariza-McNaughton L, Krumlauf R
  Development. 2001
  PubMed ID: 11532923
   
  
• Generation of a novel functional neuronal circuit in Hoxa1 mutant mice.
  del Toro ED, Borday V, Davenne M, Neun R, Rijli FM, Champagnat J
  J Neurosci. 2001
  PubMed ID: 11466434
   
  
• Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock.
  Zákány J, Kmita M, Alarcon P, de la Pompa JL, Duboule D
  Cell. 2001
  PubMed ID: 11511348
   
  
• The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function.
  Di Rocco G, Gavalas A, Popperl H, Krumlauf R, Mavilio F, Zappavigna V
  J Biol Chem. 2001
  PubMed ID: 11278854
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders.
  Ingram JL, Stodgell CJ, Hyman SL, Figlewicz DA, Weitkamp LR, Rodier PM
  Teratology. 2000
  PubMed ID: 11091361
   
  
• Altered HOX and WNT7A expression in human lung cancer.
  Calvo R, West J, Franklin W, Erickson P, Bemis L, Li E, Helfrich B, Bunn P, Roche J, Brambilla E, Rosell R, Gemmill RM, Drabkin HA
  Proc Natl Acad Sci U S A. 2000
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• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
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