HLA-DRB6
| Gene Description: |
major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| Synonyms: |
HLA-DRB6 |
| Orthologs: |
Human HLA-DRB6 (pseudo)
|
| |
|
Sources
Sources
|
Possible sources:
|
HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG
|
|
|
|
Regions of Interest Overlapping this feature from T1DBase
Top
Help
Regions Overlapping this Feature:
Human: 1
Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Gene Overview from T1DBase
Top
Help
Beta Cell Gene Atlas from T1DBase
Top
Help
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
|
| |
|
|
|
|
|
no data |
no data |
no data |
no data |
no data |
no data |
no data |
no data |
|
|
Expression Legend
|
|
|
|
The Beta Cell Gene Atlas is a collection of almost all available public microarray
data generated with pancreatic beta cells and related cell lines and types. The
expression data comes from 131 array analyses derived from 28 experiments
(open details in a new window).
The basal (untreated cell) expression signal intensity values in each array
were converted to ranks within the experiments; the highest value was used for
genes represented by more than one probe. The rank values of genes in a given cell
type were averaged with other calculated values from experiments performed with the
same cell type. The rank transformation of the expression values enable comparison
of gene expression across different organisms and tissues.
|
|
A red border around a cell indicates greater certainty in the data;
specifically, the gene has >0.95 probability of being expressed in the tissue.
|
|
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
|
| |
|
|
|
Expression Legend
|
|
|
|
Signal intensity values were converted to ranks within the experiments.
For genes represented by more than one probeset, we averaged the intensity
signals for each probeset across all tissues and chose the probeset with the
highest average value. The rank transformation of the expression values enables
comparison of gene expression across different organisms and tissues.
|
No HaemAtlas Expression pattern available for this gene.
Cross-Reference to Pathways and GO Terms
Top
Help
|
|
KEGG Network: None available
|
| |
|
|
|
|
Biocarta: None available
|
| |
|
|
|
|
Reactome: None available
|
| |
|
|
|
|
NCI-Nature Pathway Interaction Database: None available
|
| |
|
|
|
|
Gene Ontology: None available
|
| |
|
|
|
|
|
KEGG Network: None available
|
|
|
|
|
|
|
|
|
|
|
NCI-Nature Pathway Interaction Database: None available
|
|
|
|
|
Gene Ontology: None available
|
|
Publications: 7
-
Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus.
Christian N, Smikle MF, DeCeulaer K, Daniels L, Walravens MJ, Barton EN
West Indian Med J. 2007
PubMed ID: 17910142
-
Cytokine gene polymorphisms and acute human liver graft rejection.
Warlé MC, Farhan A, Metselaar HJ, Hop WC, Perrey C, Zondervan PE, Kap M, de Rave S, Kwekkeboom J, Ijzermans JN, Tilanus HW, Pravica V, Hutchinson IV, Bouma GJ
Liver Transpl. 2002
PubMed ID: 12089714
-
[Study on the gestational diabetes mellitus and histocompatibility human leukocyte antigen DRB allele polymorphism]
Song D, Liu Y, Han Y, Shang G, Hua S, Zhang H, Guo S, Jiao S
Zhonghua Fu Chan Ke Za Zhi. 2002
PubMed ID: 12133402
-
Complete cDNA sequences of the DRB6 gene from humans and chimpanzees: a possible model of a stop codon readingthrough mechanism in primates.
Moreno-Pelayo MA, Fernández-Soria VM, Paz-Artal E, Ferre-López S, Rosal M, Morales P, Varela P, Arnaiz-Villena A
Immunogenetics. 1999
PubMed ID: 10436177
-
Transcription and weak expression of HLA-DRB6: a gene with anomalies in exon 1 and other regions.
Fernandez-Soria VM, Morales P, Castro MJ, Suarez B, Recio MJ, Moreno MA, Paz-Artal E, Arnaiz-Villena A
Immunogenetics. 1998
PubMed ID: 9601939
-
Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system.
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Dupont B, Erlich HA, Mach B, Mayr WR, Parham P, Sasazuki T
Tissue Antigens. 1992
PubMed ID: 1529427
-
Primate DRB6 pseudogenes: clue to the evolutionary origin of the HLA-DR2 haplotype.
Figueroa F, O'hUigin C, Inoki H, Klein J
Immunogenetics. 1991
PubMed ID: 1937579
Model Organism Phenotype Links
Top
Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
No mouse phenotype links available for this gene.
|
|
Human
|
Mouse
|
Rat
|
|
Entrez Gene
|
3128
|
N/A
|
N/A
|
|
EnsEMBL Gene(s)
|
N/A
|
N/A
|
N/A
|
|
Unigene
|
Hs.723344
|
N/A
|
N/A
|
|
Homologene
|
HLA-DRB6
|
N/A
|
N/A
|
|
OMIM
|
N/A
|
N/A
|
N/A
|
|
GeneCards
|
HLA-DRB6
|
N/A
|
N/A
|
|
Beta Cell Genomics
|
DT.91678319
DT.95258471
|
N/A
|
N/A
|
|
Reactome
|
N/A
|
N/A
|
N/A
|
|
Plasma Peptide Atlas
|
N/A
|
N/A
|
N/A
|
|
MGI
|
N/A
|
N/A
|
N/A
|
|
WikiGenes
|
3128
|
N/A
|
N/A
|
|
External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network
Top
Help
Relevant resources:
Home 
