HLA-DQB1

  Summary from T1DBase   Top   Help
Gene Description:   RT1 class II, locus Bb; histocompatibility 2, class II antigen A, beta 1; major histocompatibility complex, class II, DQ beta 1
Synonyms:   Rmcs1, HLA-DQB1, HLA-DQB, AI845868, H2-Ab, RT1.B, RT1-Bb, I-Abeta, IDDM1, IAb, MGC94124, H2-Ab1, H-2Ab, Abeta, Ia2, Ia-2, CELIAC1
Orthologs:   Human HLA-DQB1 (protein-coding), Mouse H2-Ab1 (protein-coding), Rat RT1-Bb (protein-coding)
 
expander Sources
  Regions of Interest Overlapping this feature from T1DBase   Top   Help
Regions Overlapping this Feature:  Human: 1 Mouse: 1
expander Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Region Species Chromosomal Location Mb Number of genes Marker
MHC Human chr6:29910021..33498585 3.59 688
expander Linkage Regions: Available
  Gene Overview from T1DBase   Top   Help
expander (Human) GRCh37 - chr6:32627244..32636160 (8.92 kb)  View in Genome Browser
expander (Mouse) NCBIM37 - chr17:34400154..34406363 (6.21 kb)  View in Genome Browser
expander (Rat) RGSC3.4 - chr20:4730559..4736201 (5.64 kb)  View in Genome Browser
  Beta Cell Gene Atlas from T1DBase   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
Human Mouse Rat
ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  Tissue Expression   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
/expression/atlas-PB_CD14+_Monocytes.png /expression/atlas-PB_CD56+_NK_Cells.png /expression/atlas-PB_CD19-_B_Cells.png /expression/atlas-PB_CD4+_T_Cells.png /expression/atlas-PB_CD8+_T_Cells.png /expression/atlas-PB_BDCA4+_Dendritic_Cells.png /expression/atlas-721_B_Lymphoblasts.png /expression/atlas-Lymph_Node.png /expression/atlas-Thymus.png /expression/atlas-Salivary_Gland.png /expression/atlas-Bone_Marrow.png /expression/atlas-BM_CD34+.png /expression/atlas-Heart.png /expression/atlas-Skeletal_Muscle.png /expression/atlas-Kidney.png /expression/atlas-Liver.png /expression/atlas-Lung.png /expression/atlas-Pancreas.png /expression/atlas-Pancreatic_Islets.png /expression/atlas-Trachea.png /expression/atlas-Pituitary.png /expression/atlas-Thyroid.png /expression/atlas-Amygdala.png /expression/atlas-Caudate_Nucleus.png /expression/atlas-Cerebellum.png /expression/atlas-Hypothalamus.png /expression/atlas-Spinal_cord.png /expression/atlas-Thalamus.png /expression/atlas-Skin.png /expression/atlas-Ovary.png /expression/atlas-Placenta.png /expression/atlas-Prostate.png /expression/atlas-Testis.png /expression/atlas-Uterus.png
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  HaemAtlas Expression   Top   Help
Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.
CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56
Expression Pattern Not Detected Not Detected Not Detected Not Detected Not Detected Not Detected Not Detected Not Detected HaemAtlasProfile
expander Expression Legend
  Interactions from T1DBase   Top   Help
expander Interactions Table for HLA-DQB1:
  Cross-Reference to Pathways and GO Terms   Top   Help
expander View all
expander KEGG Network: 17
Biocarta: None available
expander Reactome: 7
NCI-Nature Pathway Interaction Database: None available
expander Gene Ontology: 17
  Publications   Top   Help
expander Type 1 Diabetes Publications: 281
expander Publications: 1483
  Model Organism Phenotype Links   Top   Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
Organism Phenotype Resources
Mouse MGI:103070 IKMC
  External Links   Top   Help
  External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network   Top   Help
dkCOIN_click Relevant resources:
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