HLA-DPB1

  Summary from T1DBase   Top   Help
Gene Description:   major histocompatibility complex, class II, DP beta 1
Synonyms:   FLJ57621, HLA-DP1B, FLJ61008, DPB1, HLA-DPB, HLA-DPB1
Orthologs:   Human HLA-DPB1 (protein-coding)
 
expander Sources
  Regions of Interest Overlapping this feature from T1DBase   Top   Help
Regions Overlapping this Feature:  Human: 1
expander Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Region Species Chromosomal Location Mb Number of genes Marker
MHC Human chr6:29910021..33498585 3.59 688
  Gene Overview from T1DBase   Top   Help
expander (Human) GRCh37 - chr6:33043703..33096890 (53.19 kb)  View in Genome Browser
  Beta Cell Gene Atlas from T1DBase   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
Human Mouse Rat
ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas
 
 
 
 
 
no data no data no data no data no data no data no data no data
expander Expression Legend
  Tissue Expression   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
/expression/atlas-PB_CD14+_Monocytes.png /expression/atlas-PB_CD56+_NK_Cells.png /expression/atlas-PB_CD19-_B_Cells.png /expression/atlas-PB_CD4+_T_Cells.png /expression/atlas-PB_CD8+_T_Cells.png /expression/atlas-PB_BDCA4+_Dendritic_Cells.png /expression/atlas-721_B_Lymphoblasts.png /expression/atlas-Lymph_Node.png /expression/atlas-Thymus.png /expression/atlas-Salivary_Gland.png /expression/atlas-Bone_Marrow.png /expression/atlas-BM_CD34+.png /expression/atlas-Heart.png /expression/atlas-Skeletal_Muscle.png /expression/atlas-Kidney.png /expression/atlas-Liver.png /expression/atlas-Lung.png /expression/atlas-Pancreas.png /expression/atlas-Pancreatic_Islets.png /expression/atlas-Trachea.png /expression/atlas-Pituitary.png /expression/atlas-Thyroid.png /expression/atlas-Amygdala.png /expression/atlas-Caudate_Nucleus.png /expression/atlas-Cerebellum.png /expression/atlas-Hypothalamus.png /expression/atlas-Spinal_cord.png /expression/atlas-Thalamus.png /expression/atlas-Skin.png /expression/atlas-Ovary.png /expression/atlas-Placenta.png /expression/atlas-Prostate.png /expression/atlas-Testis.png /expression/atlas-Uterus.png
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  HaemAtlas Expression   Top   Help
Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.
CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56
Expression Pattern Not Detected Not Detected Not Detected High High Moderate Not Detected Moderate HaemAtlasProfile
expander Expression Legend
  Interactions from T1DBase   Top   Help
expander Interactions Table for HLA-DPB1:
  Cross-Reference to Pathways and GO Terms   Top   Help
expander View all
expander KEGG Network: 17
Biocarta: None available
expander Reactome: 7
NCI-Nature Pathway Interaction Database: None available
expander Gene Ontology: 17
  Publications   Top   Help
expander Type 1 Diabetes Publications: 16
expander Publications: 263
  Model Organism Phenotype Links   Top   Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
No mouse phenotype links available for this gene.
  External Links   Top   Help
  Human Mouse Rat
Entrez Gene 3115 N/A N/A
EnsEMBL Gene(s) ENSG00000215048 ENSG00000223865 ENSG00000226826 ENSG00000229295 ENSG00000230708 ENSG00000230763 ENSG00000236693 ENSG00000237710 N/A N/A
Unigene Hs.485130 N/A N/A
Homologene HLA-DPB1 N/A N/A
OMIM 142858 N/A N/A
GeneCards HLA-DPB1 N/A N/A
Beta Cell Genomics DT.100826689 DT.121402843 DT.452653 DT.91791833 DT.91878430 DT.95269923 DT.95338993 N/A N/A
Reactome P04440 N/A N/A
Plasma Peptide Atlas N/A N/A N/A
MGI N/A N/A N/A
WikiGenes 3115 N/A N/A
  External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network   Top   Help
dkCOIN_click Relevant resources:
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