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GTF2H4

Gene Description:   general transcription factor II H, polypeptide 4; general transcription factor IIH, polypeptide 4, 52kDa Synonyms:   p44, AW545633, MGC156549, TFIIH, p52, Gtf2h4, TFB2, GTF2H4 Orthologs:   Human GTF2H4 (protein-coding), Mouse Gtf2h4 (protein-coding), Rat Gtf2h4 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL, KEGG Human-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL, KEGG Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
MHC	Human	chr6:29910021..33498585	3.59	688

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd24	Mouse	chr17:35340111..41438922	6.10	184

(Human) GRCh37 - chr6:30875961..30882814 (6.85 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr17:35804675..35810684 (61 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr20:3222265..3227921 (5.66 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Interactions Table for GTF2H4: The GTF2H4 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs GTF2H4   CDK7   BioGRID  empirical  17643375  GTF2H4   ERCC2   Reactome  predicted    GTF2H4   ERCC3   HPRD, BioGRID, Reactome  empirical  9118947  15220921  GTF2H4   ERCC5   HPRD  empirical  16246722  GTF2H4   GTF2B   BioGRID  empirical  9159119  GTF2H4   GTF2E1   HPRD, BioGRID  empirical  11113176  9159119  GTF2H4   GTF2F1   BioGRID  empirical  9159119  GTF2H4   GTF2H1   Reactome  predicted    GTF2H4   GTF2H2   BioGRID  empirical  11062469  GTF2H4   GTF2H3   Reactome  predicted    GTF2H4   POLR2A   BioGRID  empirical  9159119  GTF2H4   BRCA1   BioGRID  empirical  9159119  GTF2H4   TBP   BioGRID  empirical  9159119  GTF2H4   BTAF1   BioGRID  empirical  9159119  GTF2H4   MED21   BioGRID  empirical  9159119

View all

KEGG Network: 2   Basal transcription factors Human - 3022 Mouse - 3022 Rat - 3022 Nucleotide excision repair Human - 3420 Mouse - 3420 Rat - 3420

Biocarta: None available   None available.

Reactome: 30   DNA Repair REACT_216 Dual incision reaction in GG-NER REACT_311 Dual incision reaction in TC-NER REACT_2222 Formation and Maturation of mRNA Transcript REACT_2039 Formation of incision complex in GG-NER REACT_257 Formation of RNA Pol II elongation complex REACT_1845 Formation of the Early Elongation Complex REACT_846 Formation of transcription-coupled NER (TC-NER) repair complex REACT_1941 Gene Expression REACT_71 Global Genomic NER (GG-NER) REACT_2253 mRNA Capping REACT_1470 mRNA Processing REACT_1675 Nucleotide Excision Repair REACT_1826 RNA Pol II CTD phosphorylation and interaction with CE REACT_975 RNA Polymerase I Chain Elongation REACT_2204 RNA Polymerase I Promoter Clearance REACT_1974 RNA Polymerase I Promoter Escape REACT_1913 RNA Polymerase I Transcription REACT_1309 RNA Polymerase I Transcription Initiation REACT_953 RNA Polymerase I Transcription Termination REACT_1074 RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription REACT_21352 RNA Polymerase II Pre-transcription Events REACT_22107 RNA Polymerase II Promoter Escape REACT_2089 RNA Polymerase II Transcription REACT_1366 RNA Polymerase II Transcription Elongation REACT_833 RNA Polymerase II Transcription Initiation REACT_1851 RNA Polymerase II Transcription Initiation And Promoter Clearance REACT_834 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening REACT_1655 Transcription REACT_1788 Transcription-coupled NER (TC-NER) REACT_1628

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 25   Nucleotide-excision repair, DNA damage removal GO:0000718 Sequence-specific DNA binding transcription factor activity GO:0003700 Protein kinase activity GO:0004672 Protein binding GO:0005515 Nucleus GO:0005634 Nucleoplasm GO:0005654 Holo TFIIH complex GO:0005675 DNA repair GO:0006281 Transcription-coupled nucleotide-excision repair GO:0006283 Nucleotide-excision repair GO:0006289 Regulation of transcription, DNA-dependent GO:0006355 Transcription from RNA polymerase I promoter GO:0006360 Transcription initiation from RNA polymerase I promoter GO:0006361 Transcription elongation from RNA polymerase I promoter GO:0006362 Termination of RNA polymerase I transcription GO:0006363 Transcription from RNA polymerase II promoter GO:0006366 Transcription initiation from RNA polymerase II promoter GO:0006367 Transcription elongation from RNA polymerase II promoter GO:0006368 MRNA capping GO:0006370 Protein phosphorylation GO:0006468 DNA-dependent ATPase activity GO:0008094 RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 Gene expression GO:0010467 Viral reproduction GO:0016032 Positive regulation of viral transcription GO:0050434

	KEGG Network: 2 Basal transcription factors Human - 3022 Mouse - 3022 Rat - 3022 Nucleotide excision repair Human - 3420 Mouse - 3420 Rat - 3420
	Biocarta: None available
	Reactome: 30 DNA Repair REACT_216 Dual incision reaction in GG-NER REACT_311 Dual incision reaction in TC-NER REACT_2222 Formation and Maturation of mRNA Transcript REACT_2039 Formation of incision complex in GG-NER REACT_257 Formation of RNA Pol II elongation complex REACT_1845 Formation of the Early Elongation Complex REACT_846 Formation of transcription-coupled NER (TC-NER) repair complex REACT_1941 Gene Expression REACT_71 Global Genomic NER (GG-NER) REACT_2253 mRNA Capping REACT_1470 mRNA Processing REACT_1675 Nucleotide Excision Repair REACT_1826 RNA Pol II CTD phosphorylation and interaction with CE REACT_975 RNA Polymerase I Chain Elongation REACT_2204 RNA Polymerase I Promoter Clearance REACT_1974 RNA Polymerase I Promoter Escape REACT_1913 RNA Polymerase I Transcription REACT_1309 RNA Polymerase I Transcription Initiation REACT_953 RNA Polymerase I Transcription Termination REACT_1074 RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription REACT_21352 RNA Polymerase II Pre-transcription Events REACT_22107 RNA Polymerase II Promoter Escape REACT_2089 RNA Polymerase II Transcription REACT_1366 RNA Polymerase II Transcription Elongation REACT_833 RNA Polymerase II Transcription Initiation REACT_1851 RNA Polymerase II Transcription Initiation And Promoter Clearance REACT_834 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening REACT_1655 Transcription REACT_1788 Transcription-coupled NER (TC-NER) REACT_1628
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 25 Nucleotide-excision repair, DNA damage removal GO:0000718 Sequence-specific DNA binding transcription factor activity GO:0003700 Protein kinase activity GO:0004672 Protein binding GO:0005515 Nucleus GO:0005634 Nucleoplasm GO:0005654 Holo TFIIH complex GO:0005675 DNA repair GO:0006281 Transcription-coupled nucleotide-excision repair GO:0006283 Nucleotide-excision repair GO:0006289 Regulation of transcription, DNA-dependent GO:0006355 Transcription from RNA polymerase I promoter GO:0006360 Transcription initiation from RNA polymerase I promoter GO:0006361 Transcription elongation from RNA polymerase I promoter GO:0006362 Termination of RNA polymerase I transcription GO:0006363 Transcription from RNA polymerase II promoter GO:0006366 Transcription initiation from RNA polymerase II promoter GO:0006367 Transcription elongation from RNA polymerase II promoter GO:0006368 MRNA capping GO:0006370 Protein phosphorylation GO:0006468 DNA-dependent ATPase activity GO:0008094 RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 Gene expression GO:0010467 Viral reproduction GO:0016032 Positive regulation of viral transcription GO:0050434

Publications: 81

• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
  Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Tevfik Dorak M
  Mol Hum Reprod. 2010
  PubMed ID: 20587610
   
  
• Variation within DNA repair pathway genes and risk of multiple sclerosis.
  Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium
  Am J Epidemiol. 2010
  PubMed ID: 20522537
   
  
• A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
  Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
  Dev Cell. 2009
  PubMed ID: 20059953
   
  
• TFB2 is a transient component of the catalytic site of the human mitochondrial RNA polymerase.
  Sologub M, Litonin D, Anikin M, Mustaev A, Temiakov D
  Cell. 2009
  PubMed ID: 19945377
   
  
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
  PLoS Genet. 2009
  PubMed ID: 19851445
   
  
• New clinico-genetic classification of trichothiodystrophy.
  Morice-Picard F, Cario-André M, Rezvani H, Lacombe D, Sarasin A, Taïeb A
  Am J Med Genet A. 2009
  PubMed ID: 19681155
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• Defective transcription/repair factor IIH recruitment to specific UV lesions in trichothiodystrophy syndrome.
  Chiganças V, Lima-Bessa KM, Stary A, Menck CF, Sarasin A
  Cancer Res. 2008
  PubMed ID: 18676829
   
  
• Nucleotide excision repair driven by the dissociation of CAK from TFIIH.
  Coin F, Oksenych V, Mocquet V, Groh S, Blattner C, Egly JM
  Mol Cell. 2008
  PubMed ID: 18614043
   
  
• Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.
  Okuda M, Tanaka A, Satoh M, Mizuta S, Takazawa M, Ohkuma Y, Nishimura Y
  EMBO J. 2008
  PubMed ID: 18354501
   
  
• TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.
  Gegonne A, Weissman JD, Lu H, Zhou M, Dasgupta A, Ribble R, Brady JN, Singer DS
  Proc Natl Acad Sci U S A. 2008
  PubMed ID: 18391197
   
  
• GUDMAP: the genitourinary developmental molecular anatomy project.
  McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
  J Am Soc Nephrol. 2008
  PubMed ID: 18287559
   
  
• Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
  Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B
  Mol Cell. 2007
  PubMed ID: 17643375
   
  
• Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair.
  Coin F, Oksenych V, Egly JM
  Mol Cell. 2007
  PubMed ID: 17466626
   
  
• XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients.
  Ito S, Kuraoka I, Chymkowitch P, Compe E, Takedachi A, Ishigami C, Coin F, Egly JM, Tanaka K
  Mol Cell. 2007
  PubMed ID: 17466625
   
  
• Functional TFIIH is required for UV-induced translocation of CSA to the nuclear matrix.
  Saijo M, Hirai T, Ogawa A, Kobayashi A, Kamiuchi S, Tanaka K
  Mol Cell Biol. 2007
  PubMed ID: 17242193
   
  
• Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency.
  Kim YK, Bourgeois CF, Pearson R, Tyagi M, West MJ, Wong J, Wu SY, Chiang CM, Karn J
  EMBO J. 2006
  PubMed ID: 16874302
   
  
• Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
  Shiina T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, Gojobori T, Inoko H, Bahram S
  Genetics. 2006
  PubMed ID: 16702430
   
  
• BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
  Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
  PLoS Biol. 2006
  PubMed ID: 16602821
   
  
• Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome.
  Sarker AH, Tsutakawa SE, Kostek S, Ng C, Shin DS, Peris M, Campeau E, Tainer JA, Nogales E, Cooper PK
  Mol Cell. 2005
  PubMed ID: 16246722
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression.
  Weber A, Liu J, Collins I, Levens D
  Mol Cell Biol. 2005
  PubMed ID: 15601838
   
  
• Mouse brain organization revealed through direct genome-scale TF expression analysis.
  Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
  Science. 2004
  PubMed ID: 15618518
   
  
• Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
  Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
  Nat Methods. 2004
  PubMed ID: 15782199
   
  
• Domain architecture of the p62 subunit from the human transcription/repair factor TFIIH deduced by limited proteolysis and mass spectrometry analysis.
  Jawhari A, Boussert S, Lamour V, Atkinson RA, Kieffer B, Poch O, Potier N, van Dorsselaer A, Moras D, Poterszman A
  Biochemistry. 2004
  PubMed ID: 15533047
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A.
  Giglia-Mari G, Coin F, Ranish JA, Hoogstraten D, Theil A, Wijgers N, Jaspers NG, Raams A, Argentini M, van der Spek PJ, Botta E, Stefanini M, Egly JM, Aebersold R, Hoeijmakers JH, Vermeulen W
  Nat Genet. 2004
  PubMed ID: 15220921
   
  
• The genomic sequence and comparative analysis of the rat major histocompatibility complex.
  Hurt P, Walter L, Sudbrak R, Klages S, Müller I, Shiina T, Inoko H, Lehrach H, Günther E, Reinhardt R, Himmelbauer H
  Genome Res. 2004
  PubMed ID: 15060004
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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