NR3C1

Summary Top Help

Gene Description:

nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Synonyms:

GR, GCCR, Grl-1, NR3C1, Gcr, Nr3c1, GRL, Grl1, GCR, Grl

Orthologs:

Human NR3C1 (protein-coding), Mouse Nr3c1 (protein-coding), Rat Nr3c1 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Rat: 1

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm35	Rat	chr18:4320091..76880933	72.56	466

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr5:142657496..142815077 (157.58 kb) View in Genome Browser

(Mouse) NCBIM37 - chr18:39570199..39650955 (80.76 kb) View in Genome Browser

(Rat) RGSC3.4 - chr18:32371496..32459145 (87.65 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for NR3C1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for NR3C1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 1

Biocarta: 4

Reactome: 3

NCI-Nature Pathway Interaction Database: 6

Gene Ontology: 59

Publications from PubMed Top Help

Type 1 Diabetes Publications: 6

Publications: 1086

Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages.
Kleiman A, Hübner S, Rodriguez Parkitna JM, Neumann A, Hofer S, Weigand MA, Bauer M, Schmid W, Schütz G, Libert C, Reichardt HM, Tuckermann JP
FASEB J. 2012
PubMed ID: 22042221
BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.
Jeanneteau FD, Lambert WM, Ismaili N, Bath KG, Lee FS, Garabedian MJ, Chao MV
Proc Natl Acad Sci U S A. 2012
PubMed ID: 22232675
Association of glucocorticoid receptor polymorphism A3669G with decreased risk of developing diabetes in patients with Cushing's syndrome.
Trementino L, Appolloni G, Concettoni C, Cardinaletti M, Boscaro M, Arnaldi G
Eur J Endocrinol. 2012
PubMed ID: 22048965
FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer.
Belikov S, Holmqvist PH, Astrand C, Wrange Ö
Exp Cell Res. 2012
PubMed ID: 22001115
Casted-immobilization downregulates glucocorticoid receptor expression in rat slow-twitch soleus muscle.
Sato S, Suzuki H, Tsujimoto H, Shirato K, Tachiyashiki K, Imaizumi K
Life Sci. 2011
PubMed ID: 22036623
Metabolic gene expression changes in the hippocampus of obese epileptic male rats in the pilocarpine model of temporal lobe epilepsy.
Ruiz N, Pacheco LF, Farrell B, Cox CB, Ermolinsky BS, Garrido-Sanabria ER, Nair S
Brain Res. 2011
PubMed ID: 22050960
Ligand-independent phosphorylation of the glucocorticoid receptor integrates cellular stress pathways with nuclear receptor signaling.
Galliher-Beckley AJ, Williams JG, Cidlowski JA
Mol Cell Biol. 2011
PubMed ID: 21930780
Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells.
Baschant U, Frappart L, Rauchhaus U, Bruns L, Reichardt HM, Kamradt T, Bräuer R, Tuckermann JP
Proc Natl Acad Sci U S A. 2011
PubMed ID: 22084093
Dexamethasone-induced up-regulation of the human norepinephrine transporter involves the glucocorticoid receptor and increased binding of C/EBP-β to the proximal promoter of norepinephrine transporter.
Zha Q, Wang Y, Fan Y, Zhu MY
J Neurochem. 2011
PubMed ID: 21883217
Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder.
Szczepankiewicz A, Leszczyńska-Rodziewicz A, Pawlak J, Rajewska-Rager A, Dmitrzak-Weglarz M, Wilkosc M, Skibinska M, Hauser J
J Affect Disord. 2011
PubMed ID: 21764460
Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis.
Schweingruber N, Haine A, Tiede K, Karabinskaya A, van den Brandt J, Wüst S, Metselaar JM, Gold R, Tuckermann JP, Reichardt HM, Lühder F
J Immunol. 2011
PubMed ID: 21918186
Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer.
Pan D, Kocherginsky M, Conzen SD
Cancer Res. 2011
PubMed ID: 21868756
Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.
Murphy SH, Suzuki K, Downes M, Welch GL, De Jesus P, Miraglia LJ, Orth AP, Chanda SK, Evans RM, Verma IM
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21949408
Glucocorticoids induce mitochondrial gene transcription in HepG2 cells: role of the mitochondrial glucocorticoid receptor.
Psarra AM, Sekeris CE
Biochim Biophys Acta. 2011
PubMed ID: 21664385
Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo.
Liston C, Gan WB
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21911374
A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE
Sci Signal. 2011
PubMed ID: 21900206
Changes of glucocorticoid receptor mRNA expression in basolateral amygdale-kindled rats.
Bao GS, Cheng XQ, Hua Y, Wang ZD, Liu ZG
Chin Med J (Engl). 2011
PubMed ID: 22040414
Glucocorticoid receptor: implications for rheumatic diseases.
Kino T, Charmandari E, Chrousos GP
Clin Exp Rheumatol. 2011
PubMed ID: 22018181
Disruption of β-arrestins blocks glucocorticoid receptor and severely retards lung and liver development in mice.
Zhang M, Teng H, Shi J, Zhang Y
Mech Dev. 2011
PubMed ID: 21824517
Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.
Nguyen Dinh Cat A, Briones AM, Callera GE, Yogi A, He Y, Montezano AC, Touyz RM
Hypertension. 2011
PubMed ID: 21788604
Occlusal disharmony increases amyloid-β in the rat hippocampus.
Ekuni D, Tomofuji T, Irie K, Azuma T, Endo Y, Kasuyama K, Morita M
Neuromolecular Med. 2011
PubMed ID: 21751079
Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes.
Rao NA, McCalman MT, Moulos P, Francoijs KJ, Chatziioannou A, Kolisis FN, Alexis MN, Mitsiou DJ, Stunnenberg HG
Genome Res. 2011
PubMed ID: 21750107
Differential nuclear localisation and promoter occupancy play a role in glucocorticoid receptor ligand-specific transcriptional responses.
Hadley KE, Louw A, Hapgood JP
Steroids. 2011
PubMed ID: 21641918
Glucocorticoid receptor gene haplotype predicts increased risk of hospital admission for depressive disorders in the Helsinki birth cohort study.
Lahti J, Räikkönen K, Bruce S, Heinonen K, Pesonen AK, Rautanen A, Wahlbeck K, Kere J, Kajantie E, Eriksson JG
J Psychiatr Res. 2011
PubMed ID: 21477816
Stress and glucocorticoids regulated corticotropin releasing factor in rat prefrontal cortex.
Meng QY, Chen XN, Tong DL, Zhou JN
Mol Cell Endocrinol. 2011
PubMed ID: 21664419
Synthesized glucocorticoid, dexamethasone regulates the expressions of β₂-adrenoceptor and glucocorticoid receptor mRNAs but not proteins in slow-twitch soleus muscle of rats.
Sato S, Shirato K, Tachiyashiki K, Imaizumi K
J Toxicol Sci. 2011
PubMed ID: 21804312
Differential regulations of AQP4 and Kir4.1 by triamcinolone acetonide and dexamethasone in the healthy and inflamed retina.
Zhao M, Bousquet E, Valamanesh F, Farman N, Jeanny JC, Jaisser F, Behar-Cohen FF
Invest Ophthalmol Vis Sci. 2011
PubMed ID: 21724913
The glucocorticoid receptor and the coregulator Brm selectively modulate each other's occupancy and activity in a gene-specific manner.
Engel KB, Yamamoto KR
Mol Cell Biol. 2011
PubMed ID: 21646426
Variation in the glucocorticoid receptor gene (NR3C1) may be associated with corticosteroid dependency and resistance in children with Crohn's disease.
Krupoves A, Mack D, Deslandres C, Seidman E, Amre DK
Pharmacogenet Genomics. 2011
PubMed ID: 21633323
Expression of locus coeruleus mineralocorticoid receptor and glucocorticoid receptor in rats under single-prolonged stress.
Li M, Han F, Shi Y
Neurol Sci. 2011
PubMed ID: 21584742
Neonatal respiratory infection and adult re-infection: effect on glucocorticoid and mineralocorticoid receptors in the hippocampus in BALB/c mice.
Wynne O, Horvat JC, Kim RY, Ong LK, Smith R, Hansbro PM, Clifton VL, Hodgson DM
Brain Behav Immun. 2011
PubMed ID: 21440617
The Bcl I single nucleotide polymorphism of the human glucocorticoid receptor gene h-GR/NR3C1 promoter in patients with bronchial asthma: pilot study.
Pietras T, Panek M, Tworek D, Oszajca K, Wujcik R, Górski P, Kuna P, Szemraj J
Mol Biol Rep. 2011
PubMed ID: 21113676
Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock.
Van Bogaert T, Vandevyver S, Dejager L, Van Hauwermeiren F, Pinheiro I, Petta I, Engblom D, Kleyman A, Schütz G, Tuckermann J, Libert C
J Biol Chem. 2011
PubMed ID: 21646349
The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients.
Varricchio L, Masselli E, Alfani E, Battistini A, Migliaccio G, Vannucchi AM, Zhang W, Rondelli D, Godbold J, Ghinassi B, Whitsett C, Hoffman R, Migliaccio AR
Blood. 2011
PubMed ID: 21355091
Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor.
Rose AJ, Díaz MB, Reimann A, Klement J, Walcher T, Krones-Herzig A, Strobel O, Werner J, Peters A, Kleyman A, Tuckermann JP, Vegiopoulos A, Herzig S
Cell Metab. 2011
PubMed ID: 21723510
Differential regulation and function of 5'-untranslated GR-exon 1 transcripts.
Bockmühl Y, Murgatroyd CA, Kuczynska A, Adcock IM, Almeida OF, Spengler D
Mol Endocrinol. 2011
PubMed ID: 21527501
Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance.
Gross KL, Oakley RH, Scoltock AB, Jewell CM, Cidlowski JA
Mol Endocrinol. 2011
PubMed ID: 21527497
Effects of chronic academic stress on mental state and expression of glucocorticoid receptor α and β isoforms in healthy Japanese medical students.
Kurokawa K, Tanahashi T, Murata A, Akaike Y, Katsuura S, Nishida K, Masuda K, Kuwano Y, Kawai T, Rokutan K
Stress. 2011
PubMed ID: 21438768
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation.
Bhattacharyya S, Zhao Y, Kay TW, Muglia LJ
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21606371
Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response.
Verhoog NJ, Du Toit A, Avenant C, Hapgood JP
J Biol Chem. 2011
PubMed ID: 21474440
Associations between anthropometrical measurements, body composition, single-nucleotide polymorphisms of the hypothalamus/pituitary/adrenal (HPA) axis and HPA axis functioning.
Rutters F, Nieuwenhuizen AG, Lemmens SG, Bouwman F, Mariman E, Westerterp-Plantenga MS
Clin Endocrinol (Oxf). 2011
PubMed ID: 21521257
The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment.
Conway-Campbell BL, George CL, Pooley JR, Knight DM, Norman MR, Hager GL, Lightman SL
Mol Endocrinol. 2011
PubMed ID: 21511880
Contributions of the glucocorticoid receptor polymorphism (Bcl1) and childhood abuse to risk of bulimia nervosa.
Steiger H, Bruce K, Gauvin L, Groleau P, Joober R, Israel M, Richardson J, Kin FN
Psychiatry Res. 2011
PubMed ID: 21093928
[Effects of ginsenosides on hypothalamic-pituitary-adrenal function and brain-derived neurotrophic factor in rats exposed to chronic unpredictable mild stress].
Liu L, Luo Y, Zhang R, Guo J
Zhongguo Zhong Yao Za Zhi. 2011
PubMed ID: 21837980
Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta.
Filiberto AC, Maccani MA, Koestler D, Wilhelm-Benartzi C, Avissar-Whiting M, Banister CE, Gagne LA, Marsit CJ
Epigenetics. 2011
PubMed ID: 21521940
Glucocorticoid receptor is indispensable for physiological responses to aldosterone in epithelial Na+ channel induction via the mineralocorticoid receptor in a human colonic cell line.
Bergann T, Fromm A, Borden SA, Fromm M, Schulzke JD
Eur J Cell Biol. 2011
PubMed ID: 21354648
Transcriptional control of the human glucocorticoid receptor: identification and analysis of alternative promoter regions.
Cao-Lei L, Leija SC, Kumsta R, Wüst S, Meyer J, Turner JD, Muller CP
Hum Genet. 2011
PubMed ID: 21234764
Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription.
Tóth K, Sarang Z, Scholtz B, Brázda P, Ghyselinck N, Chambon P, Fésüs L, Szondy Z
Cell Death Differ. 2011
PubMed ID: 21072052
Pituitary glucocorticoid receptor deletion reduces vulnerability to chronic stress.
Wagner KV, Wang XD, Liebl C, Scharf SH, Müller MB, Schmidt MV
Psychoneuroendocrinology. 2011
PubMed ID: 20940090
Functional variability in corticosteroid receptors is a major component of strain differences in fat deposition and metabolic consequences of enriched diets in rat.
Marissal-Arvy N, Langlois A, Tridon C, Mormede P
Metabolism. 2011
PubMed ID: 20723946
Dynamic molecular and anatomical changes in the glucocorticoid receptor in human cortical development.
Sinclair D, Webster MJ, Wong J, Weickert CS
Mol Psychiatry. 2011
PubMed ID: 20308989
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism.
Ros-Bernal F, Hunot S, Herrero MT, Parnadeau S, Corvol JC, Lu L, Alvarez-Fischer D, Carrillo-de Sauvage MA, Saurini F, Coussieu C, Kinugawa K, Prigent A, Höglinger G, Hamon M, Tronche F, Hirsch EC, Vyas S
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21467220
Behavioral insights from mouse models of forebrain--and amygdala-specific glucocorticoid receptor genetic disruption.
Arnett MG, Kolber BJ, Boyle MP, Muglia LJ
Mol Cell Endocrinol. 2011
PubMed ID: 21094675
Glucocorticoid receptor haplotype is associated with a decreased risk of delirium in the elderly.
Manenschijn L, van Rossum EF, Jetten AM, de Rooij SE, van Munster BC
Am J Med Genet B Neuropsychiatr Genet. 2011
PubMed ID: 21438141
Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.
Kim JD, Kim H, Ekram MB, Yu S, Faulk C, Kim J
Hum Mol Genet. 2011
PubMed ID: 21233130
Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy.
Hauer D, Weis F, Papassotiropoulos A, Schmoeckel M, Beiras-Fernandez A, Lieke J, Kaufmann I, Kirchhoff F, Vogeser M, Roozendaal B, Briegel J, de Quervain D, Schelling G
Crit Care Med. 2011
PubMed ID: 21169818
The glucocorticoid receptor: pivot of depression and of antidepressant treatment?
Anacker C, Zunszain PA, Carvalho LA, Pariante CM
Psychoneuroendocrinology. 2011
PubMed ID: 20399565
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.
Mollapour M, Tsutsumi S, Truman AW, Xu W, Vaughan CK, Beebe K, Konstantinova A, Vourganti S, Panaretou B, Piper PW, Trepel JB, Prodromou C, Pearl LH, Neckers L
Mol Cell. 2011
PubMed ID: 21419342
T cell development critically depends on prethymic stromal patched expression.
Uhmann A, van den Brandt J, Dittmann K, Hess I, Dressel R, Binder C, Lühder F, Christiansen H, Fassnacht M, Bhandoola A, Wienands J, Reichardt HM, Hahn H
J Immunol. 2011
PubMed ID: 21317383
Glucocorticoid receptor signaling and prostate cancer.
Kassi E, Moutsatsou P
Cancer Lett. 2011
PubMed ID: 21078539
Glucocorticoid receptor auto-upregulation and its relation with glucocorticoid sensitivity in idiopathic nephrotic syndrome.
Chen P, Jiang T, Ouyang J, Cui Y
Int Urol Nephrol. 2011
PubMed ID: 20419394
Differential glucocorticoid receptor-mediated transcription mechanisms.
Aoyagi S, Archer TK
J Biol Chem. 2011
PubMed ID: 21127044
Respiratory syncytial virus represses glucocorticoid receptor-mediated gene activation.
Hinzey A, Alexander J, Corry J, Adams KM, Claggett AM, Traylor ZP, Davis IC, Webster Marketon JI
Endocrinology. 2011
PubMed ID: 21190962
Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. The Generation R Study.
Geelhoed JJ, van Duijn C, van Osch-Gevers L, Steegers EA, Hofman A, Helbing WA, Jaddoe VW
Early Hum Dev. 2011
PubMed ID: 21146942
Effect of treadmill exercise on blood glucose, serum corticosterone levels and glucocorticoid receptor immunoreactivity in the hippocampus in chronic diabetic rats.
Hwang IK, Yi SS, Yoo KY, Park OK, Yan B, Song W, Won MH, Yoon YS, Seong JK
Neurochem Res. 2011
PubMed ID: 21076867
Successful treatment of acute lung injury with pitavastatin in septic mice: potential role of glucocorticoid receptor expression in alveolar macrophages.
Takano K, Yamamoto S, Tomita K, Takashina M, Yokoo H, Matsuda N, Takano Y, Hattori Y
J Pharmacol Exp Ther. 2011
PubMed ID: 21057058
DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Krüppel-like factor 15 gene expression.
Asada M, Rauch A, Shimizu H, Maruyama H, Miyaki S, Shibamori M, Kawasome H, Ishiyama H, Tuckermann J, Asahara H
Lab Invest. 2011
PubMed ID: 20956975
Ginsenoside-Rg1 induces angiogenesis via non-genomic crosstalk of glucocorticoid receptor and fibroblast growth factor receptor-1.
Cheung LW, Leung KW, Wong CK, Wong RN, Wong AS
Cardiovasc Res. 2011
PubMed ID: 20855522
The human glucocorticoid receptor as an RNA-binding protein: global analysis of glucocorticoid receptor-associated transcripts and identification of a target RNA motif.
Ishmael FT, Fang X, Houser KR, Pearce K, Abdelmohsen K, Zhan M, Gorospe M, Stellato C
J Immunol. 2011
PubMed ID: 21148795
Upregulation of hepatic 11β-hydroxysteroid dehydrogenase-1 expression in calcium-deficient rats.
Takaya J, Iharada A, Okihana H, Kaneko K
Ann Nutr Metab. 2011
PubMed ID: 22142627
Binding-folding induced regulation of AF1 transactivation domain of the glucocorticoid receptor by a cofactor that binds to its DNA binding domain.
Garza AS, Khan SH, Moure CM, Edwards DP, Kumar R
PLoS One. 2011
PubMed ID: 22003412
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells.
Kay P, Schlossmacher G, Matthews L, Sommer P, Singh D, White A, Ray D
PLoS One. 2011
PubMed ID: 21984896
Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man.
Charmandari E, Chrousos GP, Lambrou GI, Pavlaki A, Koide H, Ng SS, Kino T
PLoS One. 2011
PubMed ID: 21980503
Primary generalized glucocorticoid resistance and hypersensitivity.
Charmandari E
Horm Res Paediatr. 2011
PubMed ID: 21912096
GPR50 interacts with TIP60 to modulate glucocorticoid receptor signalling.
Li J, Hand LE, Meng QJ, Loudon AS, Bechtold DA
PLoS One. 2011
PubMed ID: 21858214
Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response.
Ge X, Rameix-Welti MA, Gault E, Chase G, dos Santos Afonso E, Picard D, Schwemmle M, Naffakh N
PLoS One. 2011
PubMed ID: 21853119
TBP binding-induced folding of the glucocorticoid receptor AF1 domain facilitates its interaction with steroid receptor coactivator-1.
Khan SH, Ling J, Kumar R
PLoS One. 2011
PubMed ID: 21760925
Expression of glucocorticoid receptor and glucose transporter-1 during placental development in the diabetic rat.
Korgun ET, Acar N, Sati L, Kipmen-Korgun D, Ozen A, Unek G, Ustunel I, Demir R
Folia Histochem Cytobiol. 2011
PubMed ID: 21744335
Differences in mouse maternal care behavior - is there a genetic impact of the glucocorticoid receptor?
Chourbaji S, Hoyer C, Richter SH, Brandwein C, Pfeiffer N, Vogt MA, Vollmayr B, Gass P
PLoS One. 2011
PubMed ID: 21552522
Role of macrophage migration inhibitory factor in glucocorticoid release and glucocorticoid receptor function in rats.
Jing L, Bu M
Ann Clin Lab Sci. 2011
PubMed ID: 21325249
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Inhibition of glucocorticoid-induced alteration of vimentin by a glucocorticoid receptor antagonist RU486 in the organ-cultured rat lens.
Xie GL, Yan H, Lu ZF
Mol Vis. 2011
PubMed ID: 21245955
Glucocorticoid resistance.
van Rossum EF, van den Akker EL
Endocr Dev. 2011
PubMed ID: 21164266
Regulation of glucocorticoid receptor activity by a stress responsive transcriptional cofactor.
Davies L, Paraskevopoulou E, Sadeq M, Symeou C, Pantelidou C, Demonacos C, Krstic-Demonacos M
Mol Endocrinol. 2011
PubMed ID: 21147850
A new, lineage specific, autoup-regulation mechanism for human glucocorticoid receptor gene expression in 697 pre-B-acute lymphoblastic leukemia cells.
Geng CD, Vedeckis WV
Mol Endocrinol. 2011
PubMed ID: 21084380
Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL
Gene Expr Patterns. 2011
PubMed ID: 20932939
Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases.
De Iudicibus S, Stocco G, Martelossi S, Londero M, Ebner E, Pontillo A, Lionetti P, Barabino A, Bartoli F, Ventura A, Decorti G
J Clin Gastroenterol. 2011
PubMed ID: 20697295
Familial glucocorticoid resistance caused by a novel frameshift glucocorticoid receptor mutation.
Trebble P, Matthews L, Blaikley J, Wayte AW, Black GC, Wilton A, Ray DW
J Clin Endocrinol Metab. 2010
PubMed ID: 20861124
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule.
Ackermann D, Gresko N, Carrel M, Loffing-Cueni D, Habermehl D, Gomez-Sanchez C, Rossier BC, Loffing J
Am J Physiol Renal Physiol. 2010
PubMed ID: 20861076
The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, Dean CH
Hum Mol Genet. 2010
PubMed ID: 20843830
Glucocorticoid receptor gene haplotypes are not associated with birth anthropometry, blood pressure, glucose and insulin concentrations, and body composition in subjects born small for gestational age.
Manenschijn L, van den Akker EL, Ester WA, Leunissen RW, Willemsen RH, van Rossum EF, Koper JW, Lamberts SW, Hokken-Koelega AC
Eur J Endocrinol. 2010
PubMed ID: 20841450
Lysine 419 targets human glucocorticoid receptor for proteasomal degradation.
Wallace AD, Cao Y, Chandramouleeswaran S, Cidlowski JA
Steroids. 2010
PubMed ID: 20619282
Expression and distribution of glucocorticoid receptor isoforms in eosinophilic chronic rhinosinusitis.
Takeda K, Takeno S, Hirakawa K, Ishino T
Auris Nasus Larynx. 2010
PubMed ID: 20488636
Glucocorticoid receptor gene polymorphisms in Italian patients with eating disorders and obesity.
Cellini E, Castellini G, Ricca V, Bagnoli S, Tedde A, Rotella CM, Faravelli C, Sorbi S, Nacmias B
Psychiatr Genet. 2010
PubMed ID: 20440229
Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.
Seitz T, Thoma R, Schoch GA, Stihle M, Benz J, D'Arcy B, Wiget A, Ruf A, Hennig M, Sterner R
J Mol Biol. 2010
PubMed ID: 20850457
Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs.
Moons T, Claes S, Martens GJ, Peuskens J, Van Loo KM, Van Schijndel JE, De Hert M, van Winkel R
Schizophr Res. 2010
PubMed ID: 21050724
Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin.
Sevilla LM, Bayo P, Latorre V, Sanchis A, Pérez P
Mol Endocrinol. 2010
PubMed ID: 20880987
A large-scale candidate gene association study of age at menarche and age at natural menopause.
He C, Kraft P, Chasman DI, Buring JE, Chen C, Hankinson SE, Paré G, Chanock S, Ridker PM, Hunter DJ
Hum Genet. 2010
PubMed ID: 20734064
Reduced viability of mice with lung epithelial-specific knockout of glucocorticoid receptor.
Manwani N, Gagnon S, Post M, Joza S, Muglia L, Cornejo S, Kaplan F, Sweezey NB
Am J Respir Cell Mol Biol. 2010
PubMed ID: 20042713
A putative role for hypothalamic glucocorticoid receptors in hypertension induced by prenatal undernutrition in the rat.
Pérez H, Soto-Moyano R, Ruiz S, Hernández A, Sierralta W, Olivares R, Núñez H, Flores O, Morgan C, Valladares L, Gatica A, Flores FJ
Neurosci Lett. 2010
PubMed ID: 20674672
Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity.
Avenant C, Ronacher K, Stubsrud E, Louw A, Hapgood JP
Mol Cell Endocrinol. 2010
PubMed ID: 20561560
Frequencies of Bcl I, E22E, and N363S of h-GR/NR3C1 restriction fragment length polymorphisms of glucocorticoid receptor gene in Polish adult population.
Pietras T, Panek M, Kuprys-Lipinska I, Oszajca K, Wujcik R, Kuna P, Gorski P, Szemraj J
Med Sci Monit. 2010
PubMed ID: 20885351
Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage.
Hanna CW, Bretherick KL, Liu CC, Stephenson MD, Robinson WP
Hum Reprod. 2010
PubMed ID: 20716560
The type I interferon signaling pathway is a target for glucocorticoid inhibition.
Flammer JR, Dobrovolna J, Kennedy MA, Chinenov Y, Glass CK, Ivashkiv LB, Rogatsky I
Mol Cell Biol. 2010
PubMed ID: 20679482
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Expression of glucocorticoid receptor isoforms in human adrenocortical adenomas.
Boyle B, Butz H, Liko I, Zalatnai A, Toth M, Feldman K, Horanyi J, Igaz P, Racz K, Patocs A
Steroids. 2010
PubMed ID: 20438742
Overexpression of glucocorticoid receptor-beta in severe allergic rhinitis.
Ishida A, Ohta N, Koike S, Aoyagi M, Yamakawa M
Auris Nasus Larynx. 2010
PubMed ID: 20185258
Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing.
Wang W, Shen P, Thiyagarajan S, Lin S, Palm C, Horvath R, Klopstock T, Cutler D, Pique L, Schrijver I, Davis RW, Mindrinos M, Speed TP, Scharfe C
Nucleic Acids Res. 2010
PubMed ID: 20843780
AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38 MAPK.
Nader N, Ng SS, Lambrou GI, Pervanidou P, Wang Y, Chrousos GP, Kino T
Mol Endocrinol. 2010
PubMed ID: 20660302
Discovery of glucocorticoid receptor-beta in mice with a role in metabolism.
Hinds TD, Ramakrishnan S, Cash HA, Stechschulte LA, Heinrich G, Najjar SM, Sanchez ER
Mol Endocrinol. 2010
PubMed ID: 20660300
Regulation of glucocorticoid receptor transcription and nuclear translocation during single and repeated immobilization stress.
Noguchi T, Makino S, Matsumoto R, Nakayama S, Nishiyama M, Terada Y, Hashimoto K
Endocrinology. 2010
PubMed ID: 20660064
Role of glucocorticoid receptor polymorphism in adrenal incidentalomas.
Morelli V, Donadio F, Eller-Vainicher C, Cirello V, Olgiati L, Savoca C, Cairoli E, Salcuni AS, Beck-Peccoz P, Chiodini I
Eur J Clin Invest. 2010
PubMed ID: 20584071
Induction of glucocorticoid receptor-beta expression in epithelial cells of asthmatic airways by T-helper type 17 cytokines.
Vazquez-Tello A, Semlali A, Chakir J, Martin JG, Leung DY, Eidelman DH, Hamid Q
Clin Exp Allergy. 2010
PubMed ID: 20545708
Glucocorticoid receptor in the rat epididymis: expression, cellular distribution and regulation by steroid hormones.
Silva EJ, Queiróz DB, Honda L, Avellar MC
Mol Cell Endocrinol. 2010
PubMed ID: 20573576
Associations between common arginine vasopressin 1b receptor and glucocorticoid receptor gene variants and HPA axis responses to psychosocial stress in a child psychiatric population.
van West D, Del-Favero J, Deboutte D, Van Broeckhoven C, Claes S
Psychiatry Res. 2010
PubMed ID: 20472303
Forebrain glucocorticoid receptor overexpression increases environmental reactivity and produces a stress-induced spatial discrimination deficit.
Hebda-Bauer EK, Pletsch A, Darwish H, Fentress H, Simmons TA, Wei Q, Watson SJ, Akil H
Neuroscience. 2010
PubMed ID: 20562006
Associations of markers in 11 obesity candidate genes with maximal weight loss and weight regain in the SOS bariatric surgery cases.
Sarzynski MA, Jacobson P, Rankinen T, Carlsson B, Sjöström L, Bouchard C, Carlsson LM
Int J Obes (Lond). 2010
PubMed ID: 20733583
Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents.
Desrivières S, Lourdusamy A, Müller C, Ducci F, Wong CP, Kaakinen M, Pouta A, Hartikainen AL, Isohanni M, Charoen P, Peltonen L, Freimer N, Elliott P, Jarvelin MR, Schumann G
Addict Biol. 2010
PubMed ID: 20731635
Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.
Mwinyi J, Wenger C, Eloranta JJ, Kullak-Ublick GA
World J Gastroenterol. 2010
PubMed ID: 20712049
Metaplasticity of amygdalar responses to the stress hormone corticosterone.
Karst H, Berger S, Erdmann G, Schütz G, Joëls M
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20663957
No Associations Between Single Nucleotide Polymorphisms in Corticoid Receptor Genes and Heart Rate and Cortisol Responses to a Standardized Social Stress Test in Adolescents: The TRAILS Study.
Bouma EM, Riese H, Nolte IM, Oosterom E, Verhulst FC, Ormel J, Oldehinkel AJ
Behav Genet. 2010
PubMed ID: 20680430
AP-1 overexpression impairs corticosteroid inhibition of collagen production by fibroblasts isolated from asthmatic subjects.
Jacques E, Semlali A, Boulet LP, Chakir J
Am J Physiol Lung Cell Mol Physiol. 2010
PubMed ID: 20543003
Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.
Wang Y, Fu W, Xie F, Wang Y, Chu X, Wang H, Shen M, Wang Y, Wang Y, Sun W, Lei R, Yang L, Wu H, Foo J, Liu J, Jin L, Huang W
J Hum Genet. 2010
PubMed ID: 20485444
Intrauterine growth retardation affects expression and epigenetic characteristics of the rat hippocampal glucocorticoid receptor gene.
Ke X, Schober ME, McKnight RA, O'Grady S, Caprau D, Yu X, Callaway CW, Lane RH
Physiol Genomics. 2010
PubMed ID: 20388836
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?
Ruaño G, Thompson PD, Kane JP, Pullinger CR, Windemuth A, Seip RL, Kocherla M, Holford TR, Wu AH
Pharmacogenomics. 2010
PubMed ID: 20602615
CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells.
O'Brien KB, Alberich-Jordà M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S
Development. 2010
PubMed ID: 20530543
Glucocorticoid receptor-beta and receptor-gamma exert dominant negative effect on gene repression but not on gene induction.
Taniguchi Y, Iwasaki Y, Tsugita M, Nishiyama M, Taguchi T, Okazaki M, Nakayama S, Kambayashi M, Hashimoto K, Terada Y
Endocrinology. 2010
PubMed ID: 20484466
Expression of glucocorticoid receptor and early growth response gene 1 during postnatal development of two inbred strains of mice exposed to early life stress.
Navailles S, Zimnisky R, Schmauss C
Dev Neurosci. 2010
PubMed ID: 20453467
Nuclear receptors in leydig cell gene expression and function.
Martin LJ, Tremblay JJ
Biol Reprod. 2010
PubMed ID: 20375256
Activation of metabotropic glutamate receptor 5 in the amygdala modulates pain-like behavior.
Kolber BJ, Montana MC, Carrasquillo Y, Xu J, Heinemann SF, Muglia LJ, Gereau RW
J Neurosci. 2010
PubMed ID: 20554871
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP
Cell Metab. 2010
PubMed ID: 20519123
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
Pediatr Pulmonol. 2010
PubMed ID: 20503287
Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study.
Otte C, Wüst S, Zhao S, Pawlikowska L, Kwok PY, Whooley MA
J Clin Endocrinol Metab. 2010
PubMed ID: 20371666
Site-specific and dose-dependent effects of glucocorticoid receptor phosphorylation in yeast Saccharomyces cerevisiae.
Popovic N, Ruzdijic S, Kanazir DT, Niciforovic A, Adzic M, Paraskevopoulou E, Pantelidou C, Radojcic M, Demonacos C, Krstic-Demonacos M
Steroids. 2010
PubMed ID: 20223255
Adaptation of arcuate insulin receptor, estrogen receptor-alpha, estrogen receptor-beta, and type-II glucocorticoid receptor gene profiles to chronic intermediate insulin-induced hypoglycemia in estrogen-treated ovariectomized female rats.
Genabai NK, Briski KP
J Mol Neurosci. 2010
PubMed ID: 19953342
FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene-environment interaction.
Luijk MP, Velders FP, Tharner A, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H
Psychoneuroendocrinology. 2010
PubMed ID: 20547006
Glucocorticoid receptor knock down reveals a similar apoptotic threshold but differing gene regulation patterns in T-cell and pre-B-cell acute lymphoblastic leukemia.
Schwartz JR, Sarvaiya PJ, Vedeckis WV
Mol Cell Endocrinol. 2010
PubMed ID: 20170710
The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.
Diefenbacher ME, Litfin M, Herrlich P, Kassel O
Mol Cell Endocrinol. 2010
PubMed ID: 20153803
Comparative effects of microtubules disruption on glucocorticoid receptor functions in proliferating and quiescent cells.
Vrzal R, Gerbal-Chaloin S, Maurel P, Dvorák Z
Int J Toxicol. 2010
PubMed ID: 20448266
Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.
Holliday KL, Macfarlane GJ, Nicholl BI, Creed F, Thomson W, McBeth J
J Psychosom Res. 2010
PubMed ID: 20403506
A novel point mutation in helix 10 of the human glucocorticoid receptor causes generalized glucocorticoid resistance by disrupting the structure of the ligand-binding domain.
Nader N, Bachrach BE, Hurt DE, Gajula S, Pittman A, Lescher R, Kino T
J Clin Endocrinol Metab. 2010
PubMed ID: 20335448
Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia.
te Winkel ML, van Beek RD, de Muinck Keizer-Schrama SM, Uitterlinden AG, Hop WC, Pieters R, van den Heuvel-Eibrink MM
Haematologica. 2010
PubMed ID: 20015871
Estrogen receptor, progesterone receptor, and glucocorticoid receptor expression in normal breast tissue, breast in situ carcinoma, and invasive breast cancer.
Buxant F, Engohan-Aloghe C, Noël JC
Appl Immunohistochem Mol Morphol. 2010
PubMed ID: 19875955
Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed.
Alt SR, Turner JD, Klok MD, Meijer OC, Lakke EA, Derijk RH, Muller CP
Psychoneuroendocrinology. 2010
PubMed ID: 19782477
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Dev Cell. 2010
PubMed ID: 20412781
The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension.
Goodwin JE, Zhang J, Velazquez H, Geller DS
Biochem Biophys Res Commun. 2010
PubMed ID: 20188070
Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice.
Hensler JG, Vogt MA, Gass P
Psychoneuroendocrinology. 2010
PubMed ID: 19766402
Polymorphisms in glucocorticoid receptor gene and the outcome of childhood acute lymphoblastic leukemia (ALL).
Labuda M, Gahier A, Gagné V, Moghrabi A, Sinnett D, Krajinovic M
Leuk Res. 2010
PubMed ID: 19758697
Depression-prone mice with reduced glucocorticoid receptor expression display an altered stress-dependent regulation of brain-derived neurotrophic factor and activity-regulated cytoskeleton-associated protein.
Molteni R, Chourbaji S, Brandwein C, Racagni G, Gass P, Riva MA
J Psychopharmacol. 2010
PubMed ID: 19074532
Poor replication of candidate genes for major depressive disorder using genome-wide association data.
Bosker FJ, Hartman CA, Nolte IM, Prins BP, Terpstra P, Posthuma D, van Veen T, Willemsen G, Derijk RH, de Geus EJ, Hoogendijk WJ, Sullivan PF, Penninx BW, Boomsma DI, Snieder H, Nolen WA
Mol Psychiatry. 2010
PubMed ID: 20351714
Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice.
Zhang M, Liu X, Zhang Y, Zhao J
Dev Biol. 2010
PubMed ID: 20060823
TAK1 targeting by glucocorticoids determines JNK and IkappaB regulation in Toll-like receptor-stimulated macrophages.
Bhattacharyya S, Ratajczak CK, Vogt SK, Kelley C, Colonna M, Schreiber RD, Muglia LJ
Blood. 2010
PubMed ID: 20065289
An atlas of combinatorial transcriptional regulation in mouse and man.
Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
Cell. 2010
PubMed ID: 20211142
Neonatal intramuscular injection of plasmid encoding glucagon-like peptide-1 affects anxiety behaviour and expression of the hippocampal glucocorticoid receptor in adolescent rats.
Fan H, Wang L, Guo F, Wei S, Zhao R
J Biosci. 2010
PubMed ID: 20413910
[Effect of magnesium-free on glucocorticoid receptor expression in primary cultured cortical neurons of fetal rats in vitro].
Bo T, Yi L, Wang TM, Li J, Li XF, Mao DA
Zhongguo Dang Dai Er Ke Za Zhi. 2010
PubMed ID: 20350433
Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response.
Arambasić J, Poznanović G, Ivanović-Matić S, Bogojević D, Mihailović M, Uskoković A, Grigorov I
IUBMB Life. 2010
PubMed ID: 20155810
The effect of CAG repeat polymorphism in the glucocorticoid receptor on stress responses of mice exposed to water-immersion restraint stress.
Tomita M, Katsuyama H, Okuyama T, Watanabe Y, Hidaka K, Otsuki T, Nata M
Int J Mol Med. 2010
PubMed ID: 20127047
Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions.
Paakinaho V, Makkonen H, Jääskeläinen T, Palvimo JJ
Mol Endocrinol. 2010
PubMed ID: 20093418
Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice.
Licht CL, Kirkegaard L, Zueger M, Chourbaji S, Gass P, Aznar S, Knudsen GM
Neurochem Int. 2010
PubMed ID: 20060867
Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth.
Sommer P, Cowen RL, Berry A, Cookson A, Telfer BA, Williams KJ, Stratford IJ, Kay P, White A, Ray DW
Endocr Relat Cancer. 2010
PubMed ID: 20015838
Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression.
Inkster B, Nichols TE, Saemann PG, Auer DP, Holsboer F, Muglia P, Matthews PM
Neuroimage. 2010
PubMed ID: 20219685
Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function.
Elftman MD, Hunzeker JT, Mellinger JC, Bonneau RH, Norbury CC, Truckenmiller ME
J Immunol. 2010
PubMed ID: 20089700
Recruitment of cAMP-response element-binding protein and histone deacetylase has opposite effects on glucocorticoid receptor gene transcription.
Govindan MV
J Biol Chem. 2010
PubMed ID: 20018896
Negative relationship between expression of glucocorticoid receptor alpha and disease activity: glucocorticoid treatment of patients with systemic lupus erythematosus.
Li X, Zhang FS, Zhang JH, Wang JY
J Rheumatol. 2010
PubMed ID: 20032106
Divergent effects of amygdala glucocorticoid and mineralocorticoid receptors in the regulation of visceral and somatic pain.
Myers B, Greenwood-Van Meerveld B
Am J Physiol Gastrointest Liver Physiol. 2010
PubMed ID: 19875699
Differential alteration of heat shock protein 90 in mice modifies glucocorticoid receptor function and susceptibility to trauma.
Shen HY, Zhao Y, Chen XY, Xiong RP, Lu JL, Chen JF, Chen LY, Zhou YG
J Neurotrauma. 2010
PubMed ID: 19845467
Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations.
Schoch GA, D'Arcy B, Stihle M, Burger D, Bär D, Benz J, Thoma R, Ruf A
J Mol Biol. 2010
PubMed ID: 19913032
[The analysis of the factors influencing the development of glucocorticoid resistance in the etiopathogenesis of severe bronchial asthma].
Panek M, Pietras T, Kupryś-Lipińska I, Górski P, Kuna P, Szemraj J
Postepy Biochem. 2010
PubMed ID: 21473041
Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis.
Yu CY, Mayba O, Lee JV, Tran J, Harris C, Speed TP, Wang JC
PLoS One. 2010
PubMed ID: 21187916
Localization of mineralocorticoid receptors at mammalian synapses.
Prager EM, Brielmaier J, Bergstrom HC, McGuire J, Johnson LR
PLoS One. 2010
PubMed ID: 21179518
Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development.
Sanchis A, Bayo P, Sevilla LM, Pérez P
Int J Dev Biol. 2010
PubMed ID: 21136383
Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation.
Simard M, Côté M, Provost PR, Tremblay Y
Reprod Biol Endocrinol. 2010
PubMed ID: 21050473
Stress-induced glucocorticoid receptor activation determines functional recovery following ischemic stroke.
Zucchi FC, Matthies NF, Badr N, Metz GA
Exp Transl Stroke Med. 2010
PubMed ID: 20858282
Polymorphisms in the glucocorticoid receptor gene that modulate glucocorticoid sensitivity are associated with rheumatoid arthritis.
van Oosten MJ, Dolhain RJ, Koper JW, van Rossum EF, Emonts M, Han KH, Wouters JM, Hazes JM, Lamberts SW, Feelders RA
Arthritis Res Ther. 2010
PubMed ID: 20727199
Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors.
Schülke JP, Wochnik GM, Lang-Rollin I, Gassen NC, Knapp RT, Berning B, Yassouridis A, Rein T
PLoS One. 2010
PubMed ID: 20661446
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PLoS One. 2010
PubMed ID: 20634891
Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.
Frijters R, Fleuren W, Toonen EJ, Tuckermann JP, Reichardt HM, van der Maaden H, van Elsas A, van Lierop MJ, Dokter W, de Vlieg J, Alkema W
BMC Genomics. 2010
PubMed ID: 20525385
The effect of restraint stress on glucocorticoid receptors in mouse spleen lymphocytes: involvement of the sympathetic nervous system.
Warner A, Ovadia H, Tarcic N, Weidenfeld J
Neuroimmunomodulation. 2010
PubMed ID: 20407281
Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders.
Fingert JH, Alward WL, Wang K, Yorio T, Clark AF
Mol Vis. 2010
PubMed ID: 20376328
Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study.
Geelhoed MJ, Steegers EA, Koper JW, van Rossum EF, Moll HA, Raat H, Tiemeier H, Hofman A, Jaddoe VW
BMC Med Genet. 2010
PubMed ID: 20199670
The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression.
Lynch JT, Rajendran R, Xenaki G, Berrou I, Demonacos C, Krstic-Demonacos M
Mol Cancer. 2010
PubMed ID: 20156337
Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth.
Ryckman KK, Morken NH, White MJ, Velez DR, Menon R, Fortunato SJ, Magnus P, Williams SM, Jacobsson B
PLoS One. 2010
PubMed ID: 20140262
Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor.
Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP
Sci Signal. 2010
PubMed ID: 20124551
[Effects of neonatal recurrent seizures on glucocorticoid receptor expression in the rat brain].
Wang TM, Bo T, Wang MZ, Zhu XH, Li J, Li XF, Mao DA
Zhongguo Dang Dai Er Ke Za Zhi. 2010
PubMed ID: 20113635
Importance of glucocorticoid receptors in upper and lower airways.
Pujols L, Mullol J, Picado C
Front Biosci. 2010
PubMed ID: 20036846
Working memory performance is associated with common glucocorticoid receptor gene polymorphisms.
Kumsta R, Entringer S, Koper JW, van Rossum EF, Hellhammer DH, Wüst S
Neuropsychobiology. 2010
PubMed ID: 19940520
Site-specific phosphorylation induces functionally active conformation in the intrinsically disordered N-terminal activation function (AF1) domain of the glucocorticoid receptor.
Garza AM, Khan SH, Kumar R
Mol Cell Biol. 2010
PubMed ID: 19841061
Fasting differentially regulates plasma corticosterone-binding globulin, glucocorticoid receptor, and cell cycle in the gastric mucosa of pups and adult rats.
Ogias D, de Andrade Sá ER, Kasai A, Moisan MP, Alvares EP, Gama P
Am J Physiol Gastrointest Liver Physiol. 2010
PubMed ID: 19833863
The human glucocorticoid receptor: molecular basis of biologic function.
Nicolaides NC, Galata Z, Kino T, Chrousos GP, Charmandari E
Steroids. 2010
PubMed ID: 19818358
Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells.
Bhandare R, Damera G, Banerjee A, Flammer JR, Keslacy S, Rogatsky I, Panettieri RA, Amrani Y, Tliba O
Am J Respir Cell Mol Biol. 2010
PubMed ID: 19805480
Integrative predictive model of coronary artery calcification in atherosclerosis.
McGeachie M, Ramoni RL, Mychaleckyj JC, Furie KL, Dreyfuss JM, Liu Y, Herrington D, Guo X, Lima JA, Post W, Rotter JI, Rich S, Sale M, Ramoni MF
Circulation. 2009
PubMed ID: 19948975
Glucocorticoid receptor gene polymorphisms and potential association to chronic obstructive pulmonary disease susceptibility and severity.
Schwabe K, Vacca G, Dück R, Gillissen A
Eur J Med Res. 2009
PubMed ID: 20156759
ATP hydrolysis is essential for Bag-1M-mediated inhibition of the DNA binding by the glucocorticoid receptor.
Hong W, Chen L, Liu Y, Gao W
Biochem Biophys Res Commun. 2009
PubMed ID: 19778524
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Dev Cell. 2009
PubMed ID: 20059953
Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 1(7) glucocorticoid receptor promoter region.
Daniels WM, Fairbairn LR, van Tilburg G, McEvoy CR, Zigmond MJ, Russell VA, Stein DJ
Metab Brain Dis. 2009
PubMed ID: 19816761
Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation.
Reddy TE, Pauli F, Sprouse RO, Neff NF, Newberry KM, Garabedian MJ, Myers RM
Genome Res. 2009
PubMed ID: 19801529
Reduced hippocampal neurogenesis in the GR(+/-) genetic mouse model of depression.
Kronenberg G, Kirste I, Inta D, Chourbaji S, Heuser I, Endres M, Gass P
Eur Arch Psychiatry Clin Neurosci. 2009
PubMed ID: 19644729
Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response.
Marino S, Verzegnassi F, Tamaro P, Stocco G, Bartoli F, Decorti G, Rabusin M
Pediatr Blood Cancer. 2009
PubMed ID: 19621425
[Association of glucocorticoid receptor gene polymorphism with myasthenia gravis]
Wang LL, Xie YC, Hou SF, Feng K, Yin J, Xu XH, Li ZB, Wang YP, Xiong T, Liu JJ, Shen DG
Zhonghua Yi Xue Za Zhi. 2009
PubMed ID: 20137628
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Genomic and nongenomic cross talk between the gonadotropin-releasing hormone receptor and glucocorticoid receptor signaling pathways.
Kotitschke A, Sadie-Van Gijsen H, Avenant C, Fernandes S, Hapgood JP
Mol Endocrinol. 2009
PubMed ID: 19812390
Paradoxical stimulation of cyclooxygenase-2 expression by glucocorticoids via a cyclic AMP response element in human amnion fibroblasts.
Zhu XO, Yang Z, Guo CM, Ni XT, Li JN, Ge YC, Myatt L, Sun K
Mol Endocrinol. 2009
PubMed ID: 19797430
Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner.
Otte C, Wüst S, Zhao S, Pawlikowska L, Kwok PY, Whooley MA
Psychoneuroendocrinology. 2009
PubMed ID: 19783104
The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats.
Adzic M, Djordjevic A, Demonacos C, Krstic-Demonacos M, Radojcic MB
Int J Biochem Cell Biol. 2009
PubMed ID: 19782950
A novel isoform of human LZIP negatively regulates the transactivation of the glucocorticoid receptor.
Kang H, Kim YS, Ko J
Mol Endocrinol. 2009
PubMed ID: 19779205
Mitochondrial translocation of the glucocorticoid receptor in double-positive thymocytes correlates with their sensitivity to glucocorticoid-induced apoptosis.
Talabér G, Boldizsár F, Bartis D, Pálinkás L, Szabó M, Berta G, Sétáló G, Németh P, Berki T
Int Immunol. 2009
PubMed ID: 19737783
Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women.
Vingren JL, Kraemer WJ, Hatfield DL, Volek JS, Ratamess NA, Anderson JM, Häkkinen K, Ahtiainen J, Fragala MS, Thomas GA, Ho JY, Maresh CM
Steroids. 2009
PubMed ID: 19683543
Neonatal maternal separation alters the development of glucocorticoid receptor expression in the interpositus nucleus of the cerebellum.
Wilber AA, Wellman CL
Int J Dev Neurosci. 2009
PubMed ID: 19665541
The relationship between the expression of the glucocorticoid receptor in biopsied colonic mucosa and the glucocorticoid responsiveness of ulcerative colitis patients.
Fujishima S, Takeda H, Kawata S, Yamakawa M
Clin Immunol. 2009
PubMed ID: 19646928
Human glucocorticoid receptor isoform beta: recent understanding of its potential implications in physiology and pathophysiology.
Kino T, Su YA, Chrousos GP
Cell Mol Life Sci. 2009
PubMed ID: 19633971
Glucocorticoid receptor mRNA expression in peripheral blood mononuclear cells in high trained compared to low trained athletes and untrained subjects.
Bonifazi M, Mencarelli M, Fedele V, Ceccarelli I, Pecorelli A, Grasso G, Aloisi AM, Muscettola M
J Endocrinol Invest. 2009
PubMed ID: 19605973
The expression of c-Fos and colocalisation of c-Fos and glucocorticoid receptors in brain structures of low and high anxiety rats subjected to extinction trials and re-learning of a conditioned fear response.
Lehner M, Wisłowska-Stanek A, Taracha E, Maciejak P, Szyndler J, Skórzewska A, Turzyńska D, Sobolewska A, Hamed A, Bidziński A, Płaźnik A
Neurobiol Learn Mem. 2009
PubMed ID: 19596457
Aldosterone modulates steroid receptor binding to the endothelin-1 gene (edn1).
Stow LR, Gumz ML, Lynch IJ, Greenlee MM, Rudin A, Cain BD, Wingo CS
J Biol Chem. 2009
PubMed ID: 19638349
Defining brain region-specific glucocorticoid action during stress by conditional gene disruption in mice.
Kolber BJ, Muglia LJ
Brain Res. 2009
PubMed ID: 19361487
Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice.
Hu Z, Wang H, Lee IH, Du J, Mitch WE
J Clin Invest. 2009
PubMed ID: 19759515
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome.
Bailey MA, Mullins JJ, Kenyon CJ
Hypertension. 2009
PubMed ID: 19635986
Early maternal separation and chronic variable stress in adulthood changes the neural activity and the expression of glucocorticoid receptor in limbic structures.
Rivarola MA, Suárez MM
Int J Dev Neurosci. 2009
PubMed ID: 19563881
Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.
Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV, Wang JC
J Biol Chem. 2009
PubMed ID: 19628874
Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-kappaB modulates glucocorticoid receptor and NF-kappaB signalling in HEK-293 cells.
Psarra AM, Hermann S, Panayotou G, Spyrou G
Biochem J. 2009
PubMed ID: 19570036
Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter.
Astrand C, Belikov S, Wrange O
Exp Cell Res. 2009
PubMed ID: 19463811
Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated glucocorticoid receptor dephosphorylation.
Zhang Y, Leung DY, Nordeen SK, Goleva E
J Biol Chem. 2009
PubMed ID: 19586900
Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription.
Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, Pooley JR, Johnson TA, Voss TC, Lightman SL, Hager GL
Nat Cell Biol. 2009
PubMed ID: 19684579
Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.
Echeverría PC, Mazaira G, Erlejman A, Gomez-Sanchez C, Piwien Pilipuk G, Galigniana MD
Mol Cell Biol. 2009
PubMed ID: 19581287
Characterization of glucocorticoid receptor and hepatocyte nuclear factor 4alpha (HNF4alpha) binding to the hnf4alpha gene in the liver.
Bailly A, Briançon N, Weiss MC
Biochimie. 2009
PubMed ID: 19540905
Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals.
Wang CC, Wang SJ
Synapse. 2009
PubMed ID: 19484722
Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates.
Martinerie L, Viengchareun S, Delezoide AL, Jaubert F, Sinico M, Prevot S, Boileau P, Meduri G, Lombès M
Endocrinology. 2009
PubMed ID: 19477942
Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: Results from the EPIFUND study.
Holliday KL, Nicholl BI, Macfarlane GJ, Thomson W, Davies KA, McBeth J
Ann Rheum Dis. 2009
PubMed ID: 19723618
Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: implications for major depressive disorder.
Tatro ET, Everall IP, Kaul M, Achim CL
Brain Res. 2009
PubMed ID: 19545546
IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location.
Sanchez R, Levy E, Costea F, Sinnett D
World J Gastroenterol. 2009
PubMed ID: 19673019
Bag-1M inhibits the transactivation of the glucocorticoid receptor via recruitment of corepressors.
Hong W, Baniahmad A, Li J, Chang C, Gao W, Liu Y
FEBS Lett. 2009
PubMed ID: 19595997
Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor.
Wang SH, Liang CT, Liu YW, Huang MC, Huang SC, Hong WF, Su JG
Toxicology. 2009
PubMed ID: 19463884
Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y
Int J Mol Med. 2009
PubMed ID: 19578796
Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese.
Chen HH, Lee WJ, Fann CS, Bouchard C, Pan WH
Am J Clin Nutr. 2009
PubMed ID: 19491387
Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics.
Niu N, Manickam V, Kalari KR, Moon I, Pelleymounter LL, Eckloff BW, Wieben ED, Schaid DJ, Wang L
J Clin Endocrinol Metab. 2009
PubMed ID: 19435830
Genetic predictors of response to antidepressants in the GENDEP project.
Uher R, Huezo-Diaz P, Perroud N, Smith R, Rietschel M, Mors O, Hauser J, Maier W, Kozel D, Henigsberg N, Barreto M, Placentino A, Dernovsek MZ, Schulze TG, Kalember P, Zobel A, Czerski PM, Larsen ER, Souery D, Giovannini C, Gray JM, Lewis CM, Farmer A, Aitchison KJ, McGuffin P, Craig I
Pharmacogenomics J. 2009
PubMed ID: 19365399
Glucocorticoid receptor expression in breast cancer associates with older patient age.
Belova L, Delgado B, Kocherginsky M, Melhem A, Olopade OI, Conzen SD
Breast Cancer Res Treat. 2009
PubMed ID: 18668364
Transcriptional activation of an anti-oxidant mouse Pon2 gene by dexamethasone.
Lim JA, Kim SH
BMB Rep. 2009
PubMed ID: 19643039
Hypoxia down-regulates glucocorticoid receptor alpha and attenuates the anti-inflammatory actions of dexamethasone in human alveolar epithelial A549 cells.
Huang Y, Zhao JJ, Lv YY, Ding PS, Liu RY
Life Sci. 2009
PubMed ID: 19450611
BclI glucocorticoid receptor polymorphism and smoking in the general population.
Siiskonen SJ, Visser LE, Tiemeier H, Hofman A, Lamberts SW, Uitterlinden AG, Stricker BH
Addict Biol. 2009
PubMed ID: 19413563
Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain.
Adzic M, Djordjevic J, Djordjevic A, Niciforovic A, Demonacos C, Radojcic M, Krstic-Demonacos M
J Endocrinol. 2009
PubMed ID: 19406955
Activation of glucocorticoid receptors increases 5-HT2A receptor levels.
Trajkovska V, Kirkegaard L, Krey G, Marcussen AB, Thomsen MS, Chourbaji S, Brandwein C, Ridder S, Halldin C, Gass P, Knudsen GM, Aznar S
Exp Neurol. 2009
PubMed ID: 19379741
Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis.
van den Akker EL, Koper JW, Joosten K, de Jong FH, Hazelzet JA, Lamberts SW, Hokken-Koelega AC
Intensive Care Med. 2009
PubMed ID: 19373457
Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors.
Tyson-Capper AJ, Shiells EA, Robson SC
J Mol Endocrinol. 2009
PubMed ID: 19339282
Overrepresentation of BclI polymorphism of the glucocorticoid receptor gene in pregnant women with HELLP syndrome.
Bertalan R, Patocs A, Nagy B, Derzsy Z, Gullai N, Szappanos A, Rigo J, Racz K
Clin Chim Acta. 2009
PubMed ID: 19336230
The effect of antidepressant drugs on the HPA axis activity, glucocorticoid receptor level and FKBP51 concentration in prenatally stressed rats.
Szymańska M, Budziszewska B, Jaworska-Feil L, Basta-Kaim A, Kubera M, Leśkiewicz M, Regulska M, Lasoń W
Psychoneuroendocrinology. 2009
PubMed ID: 19195790
A population-based association study of candidate genes for depression and sleep disturbance.
Utge S, Soronen P, Partonen T, Loukola A, Kronholm E, Pirkola S, Nyman E, Porkka-Heiskanen T, Paunio T
Am J Med Genet B Neuropsychiatr Genet. 2009
PubMed ID: 19548263
Brain glucocorticoid receptors are necessary for the rhythmic expression of the clock protein, PERIOD2, in the central extended amygdala in mice.
Segall LA, Milet A, Tronche F, Amir S
Neurosci Lett. 2009
PubMed ID: 19429162
Characterization of a glucocorticoid receptor gene (GR, NR3C1) promoter polymorphism reveals functionality and extends a haplotype with putative clinical relevance.
Kumsta R, Moser D, Streit F, Koper JW, Meyer J, Wüst S
Am J Med Genet B Neuropsychiatr Genet. 2009
PubMed ID: 18663733
Effect of glucocorticoid receptor gene polymorphisms in Guillain-Barré syndrome.
Dekker MJ, van den Akker EL, Koper JW, Manenschijn L, Geleijns K, Ruts L, van Rijs W, Tio-Gillen AP, van Doorn PA, Lamberts SW, Jacobs BC
J Peripher Nerv Syst. 2009
PubMed ID: 19691529
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
A glucocorticoid receptor gene haplotype (TthIII1/ER22/23EK/9beta) is associated with a more aggressive disease course in multiple sclerosis.
van Winsen LM, Manenschijn L, van Rossum EF, Crusius JB, Crusius BA, Koper JW, Polman CH, Uitdehaag BM
J Clin Endocrinol Metab. 2009
PubMed ID: 19318444
Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism.
Yoshikawa N, Nagasaki M, Sano M, Tokudome S, Ueno K, Shimizu N, Imoto S, Miyano S, Suematsu M, Fukuda K, Morimoto C, Tanaka H
Am J Physiol Endocrinol Metab. 2009
PubMed ID: 19293335
Glucocorticoid replacement therapy and pharmacogenetics in Addison's disease: effects on bone.
Løvås K, Gjesdal CG, Christensen M, Wolff AB, Almås B, Svartberg J, Fougner KJ, Syversen U, Bollerslev J, Falch JA, Hunt PJ, Chatterjee VK, Husebye ES
Eur J Endocrinol. 2009
PubMed ID: 19282465
Postnatal glucocorticoid excess due to pituitary glucocorticoid receptor deficiency: differential short- and long-term consequences.
Schmidt MV, Sterlemann V, Wagner K, Niederleitner B, Ganea K, Liebl C, Deussing JM, Berger S, Schütz G, Holsboer F, Müller MB
Endocrinology. 2009
PubMed ID: 19213843
A High-Density Association Study of 383 Candidate Genes for Volumetric Bone Density at the Femoral Neck and Lumbar Spine among Older Men.
Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, for the MrOS Research Group
J Bone Miner Res. 2009
PubMed ID: 19453261
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.
Bougarne N, Paumelle R, Caron S, Hennuyer N, Mansouri R, Gervois P, Staels B, Haegeman G, De Bosscher K
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19376972
Asthma pharmacogenetic study using finite mixture models to handle drug-response heterogeneity.
York TP, Vargas-Irwin C, Anderson WH, van den Oord EJ
Pharmacogenomics. 2009
PubMed ID: 19450127
Activation of the GDNF-inducible transcription factor (GIF) gene promoter by glucocorticoid and progesterone.
Lee SH, Jang MK, Kim OS, Lee OH, Kim NY, Yoo KH, Lee DG, Shong YH, Mouradian MM
J Steroid Biochem Mol Biol. 2009
PubMed ID: 19429458
Interaction between the glucocorticoid and erythropoietin receptors in human erythroid cells.
Stellacci E, Di Noia A, Di Baldassarre A, Migliaccio G, Battistini A, Migliaccio AR
Exp Hematol. 2009
PubMed ID: 19375647
Chronic blockade of hindbrain glucocorticoid receptors reduces blood pressure responses to novel stress and attenuates adaptation to repeated stress.
Bechtold AG, Patel G, Hochhaus G, Scheuer DA
Am J Physiol Regul Integr Comp Physiol. 2009
PubMed ID: 19279295
Distributions of glucocorticoid receptor gene polymorphisms in a Chinese Han population and associations with outcome after major trauma.
Duan ZX, Gu W, Du DY, Hu P, Jiang DP, Zhu PF, Wang ZG, Jiang JX
Injury. 2009
PubMed ID: 19230884
Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: reversal by the anxiolytic chlordiazepoxide.
Curtin NM, Boyle NT, Mills KH, Connor TJ
Brain Behav Immun. 2009
PubMed ID: 19217938
MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain.
Vreugdenhil E, Verissimo CS, Mariman R, Kamphorst JT, Barbosa JS, Zweers T, Champagne DL, Schouten T, Meijer OC, de Kloet ER, Fitzsimons CP
Endocrinology. 2009
PubMed ID: 19131573
Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells.
Liberman AC, Druker J, Refojo D, Holsboer F, Arzt E
FASEB J. 2009
PubMed ID: 19124555
Conditional transgenic mice for studying the role of the glucocorticoid receptor in the renal collecting duct.
Nguyen Dinh Cat A, Ouvrard-Pascaud A, Tronche F, Clemessy M, Gonzalez-Nunez D, Farman N, Jaisser F
Endocrinology. 2009
PubMed ID: 19106216
Glucocorticoid receptor changes associate with age in the paraventricular nucleus of type II diabetic rat model.
Yi SS, Hwang IK, Chun MS, Kim YN, Kim IY, Lee IS, Seong JK, Yoon YS
Neurochem Res. 2009
PubMed ID: 18758953
DNA binding site sequence directs glucocorticoid receptor structure and activity.
Meijsing SH, Pufall MA, So AY, Bates DL, Chen L, Yamamoto KR
Science. 2009
PubMed ID: 19372434
Glucocorticoid receptor (GR) beta has intrinsic, GRalpha-independent transcriptional activity.
Kino T, Manoli I, Kelkar S, Wang Y, Su YA, Chrousos GP
Biochem Biophys Res Commun. 2009
PubMed ID: 19248771
Neuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth.
Gautam D, Jeon J, Starost MF, Han SJ, Hamdan FF, Cui Y, Parlow AF, Gavrilova O, Szalayova I, Mezey E, Wess J
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19332789
Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in GR-deficient BE(2)C and T84 cells in vitro.
Tsugita M, Iwasaki Y, Nishiyama M, Taguchi T, Shinahara M, Taniguchi Y, Kambayashi M, Nishiyama A, Gomez-Sanchez CE, Terada Y, Hashimoto K
Mol Cell Endocrinol. 2009
PubMed ID: 19146914
Fluoroquinolones reduce carrageenan-induced edema in rats and the involvement of the glucocorticoid receptor system.
Ogino H, Yamada K, Yuhara M, Tsuchida S, Maezawa K, Kizu J, Hori S
J Infect Chemother. 2009
PubMed ID: 19396522
Determination of genetic predisposition to patent ductus arteriosus in preterm infants.
Dagle JM, Lepp NT, Cooper ME, Schaa KL, Kelsey KJ, Orr KL, Caprau D, Zimmerman CR, Steffen KM, Johnson KJ, Marazita ML, Murray JC
Pediatrics. 2009
PubMed ID: 19336370
Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R
Pediatr Infect Dis J. 2009
PubMed ID: 19258923
Alteration of 11beta-hydroxysteroid dehydrogenase type 1 in skeletal muscle in a rat model of type 2 diabetes.
Zhang M, Lv XY, Li J, Xu ZG, Chen L
Mol Cell Biochem. 2009
PubMed ID: 19118409
Calreticulin mediated glucocorticoid receptor export is involved in beta-catenin translocation and Wnt signalling inhibition in human osteoblastic cells.
Olkku A, Mahonen A
Bone. 2009
PubMed ID: 19100874
Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survival.
Parlato R, Otto C, Tuckermann J, Stotz S, Kaden S, Gröne HJ, Unsicker K, Schütz G
Endocrinology. 2009
PubMed ID: 19036879
Characterization of a novel gain of function glucocorticoid receptor knock-in mouse.
Zhang J, Ge R, Matte-Martone C, Goodwin J, Shlomchik WD, Mamula MJ, Kooshkabadi A, Hardy MP, Geller D
J Biol Chem. 2009
PubMed ID: 19017639
The N363S polymorphism in the glucocorticoid receptor gene: effects on visceral fat assessed by abdominal computed tomography.
Cercato C, Halpern A, Frazzatto ES, Guazzelli IC, Villares SM
Arq Bras Endocrinol Metabol. 2009
PubMed ID: 19466222
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.
McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonté B, Szyf M, Turecki G, Meaney MJ
Nat Neurosci. 2009
PubMed ID: 19234457
Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking.
Ambroggi F, Turiault M, Milet A, Deroche-Gamonet V, Parnaudeau S, Balado E, Barik J, van der Veen R, Maroteaux G, Lemberger T, Schütz G, Lazar M, Marinelli M, Piazza PV, Tronche F
Nat Neurosci. 2009
PubMed ID: 19234455
Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction.
Ronacher K, Hadley K, Avenant C, Stubsrud E, Simons SS, Louw A, Hapgood JP
Mol Cell Endocrinol. 2009
PubMed ID: 19007848
The protective effect of the ER22/23EK polymorphism against an excessive weight gain during pregnancy.
Bertalan R, Patocs A, Boyle B, Rigo J, Racz K
Gynecol Endocrinol. 2009
PubMed ID: 19241242
Glucocorticoid receptor gene variant is associated with increased body fatness in youngsters.
Voorhoeve PG, van den Akker EL, van Rossum EF, Koper JW, van Mechelen W, Lamberts SW, Delemarre-van de Waal HA
Clin Endocrinol (Oxf). 2009
PubMed ID: 19222494
Functional glucocorticoid receptor gene variants do not underlie the high variability of 17-hydroxyprogesterone screening values in healthy newborns.
Schreiner F, Tozakidou M, Maslak R, Holtkamp U, Peter M, Gohlke B, Woelfle J
Eur J Endocrinol. 2009
PubMed ID: 19174530
High resolution melting (HRM) analysis for the detection of ER22/23EK, BclI, and N363S polymorphisms of the glucocorticoid receptor gene.
Maltese P, Canestrari E, Palma L, Ruzzo A, Corini F, Menotta M, Andreoni F, Latiano A, Annese V, Magnani M
J Steroid Biochem Mol Biol. 2009
PubMed ID: 19429432
[Effects of a formula of components from Shengmai Powder on glucocorticoid receptor in rats after thermal injury].
Lu X, Cheng BB, Ling CQ, Yue XQ, Li B
Zhong Xi Yi Jie He Xue Bao. 2009
PubMed ID: 19216853
Functional polymorphism of the glucocorticoid receptor gene associates with mania and hypomania in bipolar disorder.
Spijker AT, van Rossum EF, Hoencamp E, DeRijk RH, Haffmans J, Blom M, Manenschijn L, Koper JW, Lamberts SW, Zitman FG
Bipolar Disord. 2009
PubMed ID: 19133972
Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.
Velez DR, Fortunato S, Thorsen P, Lombardi SJ, Williams SM, Menon R
Am J Obstet Gynecol. 2009
PubMed ID: 19019335
A RAS recruitment screen identifies ZKSCAN4 as a glucocorticoid receptor-interacting protein.
Ecker K, Lorenz A, Wolf F, Ploner C, Böck G, Duncan T, Geley S, Helmberg A
J Mol Endocrinol. 2009
PubMed ID: 19008334
Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.
Ruaño G, Bernene J, Windemuth A, Bower B, Wencker D, Seip RL, Kocherla M, Holford TR, Petit WA, Hanks S
Clin Chim Acta. 2009
PubMed ID: 18996102
Receptor mutation is not a common mechanism of naturally occurring glucocorticoid resistance in leukaemia cell lines.
Beesley AH, Weller RE, Senanayake S, Welch M, Kees UR
Leuk Res. 2009
PubMed ID: 18789525
Glutathione-S-transferase-P1 I105V polymorphism and response to antenatal betamethasone in the prevention of respiratory distress syndrome.
Oretti C, Marino S, Mosca F, Colnaghi MR, De Iudicibus S, Drigo I, Stocco G, Bartoli F, Decorti G, Demarini S
Eur J Clin Pharmacol. 2009
PubMed ID: 19183974
Long-term low level glucocorticoid exposure induces persistent repression in chromatin.
Burkhart BA, Ivey ML, Archer TK
Mol Cell Endocrinol. 2009
PubMed ID: 19007849
BclI polymorphism of the glucocorticoid receptor gene is associated with decreased bone mineral density in patients with endogenous hypercortisolism.
Szappanos A, Patócs A, Tőke J, Boyle B, Sereg M, Majnik J, Borgulya G, Varga I, Likó I, Rácz K, Tóth M
Clin Endocrinol (Oxf). 2009
PubMed ID: 19207316
Dependence of dexamethasone-induced Akt/FOXO1 signaling, upregulation of MAFbx, and protein catabolism upon the glucocorticoid receptor.
Zhao W, Qin W, Pan J, Wu Y, Bauman WA, Cardozo C
Biochem Biophys Res Commun. 2009
PubMed ID: 19059383
Subregion-specific differences in translocation patterns of mineralocorticoid and glucocorticoid receptors in rat hippocampus.
Sarabdjitsingh RA, Meijer OC, Schaaf MJ, de Kloet ER
Brain Res. 2009
PubMed ID: 19007760
Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter.
Numakawa T, Kumamaru E, Adachi N, Yagasaki Y, Izumi A, Kunugi H
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19126684
Electroconvulsive stimulations normalizes stress-induced changes in the glucocorticoid receptor and behaviour.
Hageman I, Nielsen M, Wortwein G, Diemer NH, Jorgensen MB
Behav Brain Res. 2009
PubMed ID: 18725247
A new link between steroid resistance, glucocorticoid receptor and nuclear factor kappa B p65 in idiopathic nephrotic syndrome.
Szilagyi K, Podracka L, Franke NE, Mojzis J, Mirossay L
Neuro Endocrinol Lett. 2009
PubMed ID: 20035271
Inducible gene manipulations in serotonergic neurons.
Weber T, Böhm G, Hermann E, Schütz G, Schönig K, Bartsch D
Front Mol Neurosci. 2009
PubMed ID: 19936315
Transcriptional effects of glucocorticoid receptors in the dentate gyrus increase anxiety-related behaviors.
Sarrazin N, Di Blasi F, Roullot-Lacarrière V, Rougé-Pont F, Le Roux A, Costet P, Revest JM, Piazza PV
PLoS One. 2009
PubMed ID: 19888328
Genetical genomic determinants of alcohol consumption in rats and humans.
Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hübner N, Heinig M, Pravenec M, Mangion J, Legault L, Dongier M, Conigrave KM, Whitfield JB, Saunders J, Grant B, Hoffman PL, WHO/ISBRA Study on State and Trait Markers of Alcoholism
BMC Biol. 2009
PubMed ID: 19874574
Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis.
Jia Y, Viswakarma N, Fu T, Yu S, Rao MS, Borensztajn J, Reddy JK
Gene Expr. 2009
PubMed ID: 19630272
Comparison of gene transcription between subcutaneous and visceral adipose tissue in Chinese adults.
Zha JM, Di WJ, Zhu T, Xie Y, Yu J, Liu J, Chen P, Ding G
Endocr J. 2009
PubMed ID: 19564704
Nestin modulates glucocorticoid receptor function by cytoplasmic anchoring.
Reimer R, Helmbold H, Szalay B, Hagel C, Hohenberg H, Deppert W, Bohn W
PLoS One. 2009
PubMed ID: 19562035
If Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.
Menon R, Pearce B, Velez DR, Merialdi M, Williams SM, Fortunato SJ, Thorsen P
Reprod Biol Endocrinol. 2009
PubMed ID: 19527514
Stress type dependence of expression and cytoplasmic-nuclear partitioning of glucocorticoid receptor, hsp90 and hsp70 in Wistar rat brain.
Djordjevic A, Adzic M, Djordjevic J, Radojcic MB
Neuropsychobiology. 2009
PubMed ID: 19521113
[Expression of glucocorticoid receptors alpha and beta in mononuclear cells of peripheral blood in patients with glucocorticoid-induced ocular hypertension].
Li GG, Zhang H, Liu R, Xia Y, Bi JJ
Zhonghua Yan Ke Za Zhi. 2009
PubMed ID: 19484926
Glucocorticoid receptor gene polymorphism is less frequent in children born small for gestational age without catch-up growth.
Voorhoeve PG, van den Akker EL, Lamberts SW, Delemarre-van de Waal HA, Hokken-Koelega AC
Horm Res. 2009
PubMed ID: 19188741
Timing is critical for effective glucocorticoid receptor mediated repression of the cAMP-induced CRH gene.
van der Laan S, de Kloet ER, Meijer OC
PLoS One. 2009
PubMed ID: 19177170
Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity.
Wolf IM, Periyasamy S, Hinds T, Yong W, Shou W, Sanchez ER
J Steroid Biochem Mol Biol. 2009
PubMed ID: 19073255
A novel mitogen-activated protein kinase phosphatase-1 and glucocorticoid receptor (GR) interacting protein-1-dependent combinatorial mechanism of gene transrepression by GR.
Cho IJ, Kim SG
Mol Endocrinol. 2009
PubMed ID: 18945810
Role of RHOB in the antiproliferative effect of glucocorticoid receptor on macrophage RAW264.7 cells.
Wang X, Chen Y, Wang Y, Zhu X, Ma Y, Zhang S, Lu J
J Endocrinol. 2009
PubMed ID: 18840672
Modulation of glucocorticoid receptor function and expression in adolescent moderate asthma.
Perisić T, Srećković M, Matić G
Respiration. 2009
PubMed ID: 18799869
GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression.
Chinenov Y, Sacta MA, Cruz AR, Rogatsky I
Proc Natl Acad Sci U S A. 2008
PubMed ID: 19074285
Variation in Catechol-O-Methyltransferase Is Associated with Duloxetine Response in a Clinical Trial for Major Depressive Disorder.
Perlis RH, Fijal B, Adams DH, Sutton VK, Trivedi MH, Houston JP
Biol Psychiatry. 2008
PubMed ID: 19095219
Mutation screen and association analysis of the glucocorticoid receptor gene (NR3C1) in childhood-onset mood disorders (COMD).
Mill J, Wigg K, Burcescu I, Vetró A, Kiss E, Kapornai K, Tamás Z, Baji I, Gádoros J, Kennedy JL, Kovacs M, Barr CL, The International Consortium for Childhood‐Onset Mood Disorders
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 19089807
Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, The Psychiatric Genetics Network GroupComplete list of members appeared as Supplementary Note.
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 19086053
Bag-1M is a component of the in vivo DNA-glucocorticoid receptor complex at hormone-regulated promoter.
Hong W, Baniahmad A, Liu Y, Li H
J Mol Biol. 2008
PubMed ID: 18822299
Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: New evidence for a gene-environment interaction.
Bet PM, Penninx BW, Bochdanovits Z, Uitterlinden AG, Beekman AT, van Schoor NM, Deeg DJ, Hoogendijk WJ
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 19051288
Glucocorticoid receptor polymorphisms and intraocular pressure response to intravitreal triamcinolone acetonide.
Gerzenstein SM, Pletcher MT, Cervino AC, Tsinoremas NF, Young B, Puliafito CA, Fini ME, Schwartz SG
Ophthalmic Genet. 2008
PubMed ID: 19005987
A conserved molecular mechanism is responsible for the auto-up-regulation of glucocorticoid receptor gene promoters.
Geng CD, Schwartz JR, Vedeckis WV
Mol Endocrinol. 2008
PubMed ID: 18945813
Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles.
Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA
Mol Cell Biol. 2008
PubMed ID: 18838540
Farnesylation of Ydj1 is required for in vivo interaction with Hsp90 client proteins.
Flom GA, Lemieszek M, Fortunato EA, Johnson JL
Mol Biol Cell. 2008
PubMed ID: 18829866
A novel point mutation in the amino terminal domain of the human glucocorticoid receptor (hGR) gene enhancing hGR-mediated gene expression.
Charmandari E, Ichijo T, Jubiz W, Baid S, Zachman K, Chrousos GP, Kino T
J Clin Endocrinol Metab. 2008
PubMed ID: 18827003
Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes by hexamethylene bisacetamide-inducible protein 1.
Shimizu N, Yoshikawa N, Wada T, Handa H, Sano M, Fukuda K, Suematsu M, Sawai T, Morimoto C, Tanaka H
Mol Endocrinol. 2008
PubMed ID: 18801933
Critical role of macrophages in glucocorticoid driven vascular calcification in a mouse-model of atherosclerosis.
Preusch MR, Rattazzi M, Albrecht C, Merle U, Tuckermann J, Schütz G, Blessing E, Zoppellaro G, Pauletto P, Krempien R, Rosenfeld ME, Katus HA, Bea F
Arterioscler Thromb Vasc Biol. 2008
PubMed ID: 18787189
Expression of glucocorticoid receptor messenger ribonucleic acid transcripts in the human placenta at term.
Johnson RF, Rennie N, Murphy V, Zakar T, Clifton V, Smith R
J Clin Endocrinol Metab. 2008
PubMed ID: 18728163
Modulation of transcription parameters in glucocorticoid receptor-mediated repression.
Sun Y, Tao YG, Kagan BL, He Y, Jr SS
Mol Cell Endocrinol. 2008
PubMed ID: 18583028
Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.
Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K
J Biol Chem. 2008
PubMed ID: 18772142
Signal regulatory protein alpha1 is involved in the inhibitory effect of glucocorticoid receptor on the proliferation of murine macrophage RAW264.7 cell and mouse peritoneal macrophage.
Wang X, Li Y, Zhu X, Wang Y, Diao F, Lu J
J Mol Endocrinol. 2008
PubMed ID: 18728125
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE
FASEB J. 2008
PubMed ID: 18697839
The role of the forebrain glucocorticoid receptor in acute and chronic stress.
Furay AR, Bruestle AE, Herman JP
Endocrinology. 2008
PubMed ID: 18617609
No association of glucocorticoid receptor polymorphisms with asthma and response to glucocorticoids.
Szczepankiewicz A, Bręborowicz A, Sobkowiak P, Popiel A
Adv Med Sci. 2008
PubMed ID: 18952539
Glucocorticoid Receptor Gene Variant in the 3' Untranslated Region is Associated with Multiple Measures of Blood Pressure.
Chung CC, Shimmin L, Natarajan S, Hanis CL, Boerwinkle E, Hixson JE
J Clin Endocrinol Metab. 2008
PubMed ID: 18854398
Association of HPA axis genes with suicidal behaviour in schizophrenia.
De Luca V, Tharmalingam S, Zai C, Potapova N, Strauss J, Vincent J, Kennedy J
J Psychopharmacol. 2008
PubMed ID: 18838498
[Analgesic effect of corticotropin releasing factor (CRF) on somatic pain sensitivity: participation of glucocorticoid and CRF-2 receptors]
Iarushkina NI, Bagaeva TR, Filaretova LP
Ross Fiziol Zh Im I M Sechenova. 2008
PubMed ID: 19065825
Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-beta.
Sun H, Sheveleva E, Xu B, Inoue H, Bowden TG, Chen QM
Am J Physiol Cell Physiol. 2008
PubMed ID: 18650268
Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes.
Menconi M, Gonnella P, Petkova V, Lecker S, Hasselgren PO
J Cell Biochem. 2008
PubMed ID: 18615595
The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene.
Waddell DS, Baehr LM, van den Brandt J, Johnsen SA, Reichardt HM, Furlow JD, Bodine SC
Am J Physiol Endocrinol Metab. 2008
PubMed ID: 18612045
Glucocorticoid receptor variants may predispose to rheumatoid arthritis susceptibility.
Chatzikyriakidou A, Georgiou I, Voulgari PV, Georgiadis AN, Argyriou ES, Drosos AA
Scand J Rheumatol. 2008
PubMed ID: 18830906
Two common haplotypes of the glucocorticoid receptor gene are associated with increased susceptibility to cardiovascular disease in men with familial hypercholesterolemia.
Koeijvoets KC, van der Net JB, van Rossum EF, Steyerberg EW, Defesche JC, Kastelein JJ, Lamberts SW, Sijbrands EJ
J Clin Endocrinol Metab. 2008
PubMed ID: 18812484
Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase.
Gong H, Jarzynka MJ, Cole TJ, Lee JH, Wada T, Zhang B, Gao J, Song WC, DeFranco DB, Cheng SY, Xie W
Cancer Res. 2008
PubMed ID: 18794126
Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain.
van der Laan S, Sarabdjitsingh RA, Van Batenburg MF, Lachize SB, Li H, Dijkmans TF, Vreugdenhil E, de Kloet ER, Meijer OC
J Neurochem. 2008
PubMed ID: 18643788
Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor.
Rice L, Waters CE, Eccles J, Garside H, Sommer P, Kay P, Blackhall FH, Zeef L, Telfer B, Stratford I, Clarke R, Singh D, Stevens A, White A, Ray DW
J Endocrinol. 2008
PubMed ID: 18583474
Hepatocyte nuclear factor-1alpha regulates glucocorticoid receptor expression to control postnatal body growth.
Lin WY, Hu YJ, Lee YH
Am J Physiol Gastrointest Liver Physiol. 2008
PubMed ID: 18583462
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes.
Kim JH, Yang CK, Heo K, Roeder RG, An W, Stallcup MR
Mol Cell. 2008
PubMed ID: 18722177
Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning.
Kolber BJ, Roberts MS, Howell MP, Wozniak DF, Sands MS, Muglia LJ
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18695245
Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors.
Sharma S, Lichtenstein A
Blood. 2008
PubMed ID: 18515658
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
Mol Cell. 2008
PubMed ID: 18691976
Interaction and functional interference of glucocorticoid receptor and SOCS1.
Haffner MC, Jurgeit A, Berlato C, Geley S, Parajuli N, Yoshimura A, Doppler W
J Biol Chem. 2008
PubMed ID: 18524780
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
Expression of glucocorticoid receptor in the brain of rats during postnatal ontogeny.
Ordyan NE, Galeeva AY, Pivina SG
Bull Exp Biol Med. 2008
PubMed ID: 19145310
Psychological stress impairs the local CD8+ T cell response to mucosal HSV-1 infection and allows for increased pathogenicity via a glucocorticoid receptor-mediated mechanism.
Ashcraft KA, Hunzeker J, Bonneau RH
Psychoneuroendocrinology. 2008
PubMed ID: 18657369
Glucocorticoid receptor phosphorylation differentially affects target gene expression.
Chen W, Dang T, Blind RD, Wang Z, Cavasotto CN, Hittelman AB, Rogatsky I, Logan SK, Garabedian MJ
Mol Endocrinol. 2008
PubMed ID: 18483179
Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism.
Umekawa T, Sugiyama T, Kihira T, Murabayashi N, Zhang L, Nagao K, Kamimoto Y, Ma N, Yodoi J, Sagawa N
Endocrinology. 2008
PubMed ID: 18450962
Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats.
Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Keller CE, Almon RR, Jusko WJ
J Pharmacol Exp Ther. 2008
PubMed ID: 18448865
The PKC and ERK/MAPK pathways regulate glucocorticoid action on TRH transcription.
Cote-Vélez A, Pérez-Martínez L, Charli JL, Joseph-Bravo P
Neurochem Res. 2008
PubMed ID: 18427988
Development of glucocorticoid receptor regulation in the rat forebrain: implications for adverse effects of glucocorticoids in preterm infants.
Slotkin TA, Seidler FJ, Wood CR, Lau C
Brain Res Bull. 2008
PubMed ID: 18534262
Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
Lu Y, Dollé ME, Imholz S, Slot RV, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM
J Lipid Res. 2008
PubMed ID: 18660489
Culture condition and embryonic stage dependent silence of glucocorticoid receptor expression in hippocampal neurons.
Xiao L, Chen Y
J Steroid Biochem Mol Biol. 2008
PubMed ID: 18625317
Association between birth weight in preterm neonates and the BclI polymorphism of the glucocorticoid receptor gene.
Bertalan R, Patocs A, Vasarhelyi B, Treszl A, Varga I, Szabo E, Tamas J, Toke J, Boyle B, Nobilis A, Rigo J, Racz K
J Steroid Biochem Mol Biol. 2008
PubMed ID: 18595687
Glucocorticoid sensitivity in fibromyalgia patients: decreased expression of corticosteroid receptors and glucocorticoid-induced leucine zipper.
Macedo JA, Hesse J, Turner JD, Meyer J, Hellhammer DH, Muller CP
Psychoneuroendocrinology. 2008
PubMed ID: 18468809
DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner.
Zhou J, Oakley RH, Cidlowski JA
Mol Endocrinol. 2008
PubMed ID: 18417736
Loss of glucocorticoid receptor function in the pituitary results in early postnatal lethality.
Erdmann G, Schütz G, Berger S
Endocrinology. 2008
PubMed ID: 18372328
Response to prednisone in relation to NR3C1 intron B polymorphisms in childhood nephrotic syndrome.
Zalewski G, Wasilewska A, Zoch-Zwierz W, Chyczewski L
Pediatr Nephrol. 2008
PubMed ID: 18343955
Role of the hinge region of glucocorticoid receptor for HEXIM1-mediated transcriptional repression.
Yoshikawa N, Shimizu N, Sano M, Ohnuma K, Iwata S, Hosono O, Fukuda K, Morimoto C, Tanaka H
Biochem Biophys Res Commun. 2008
PubMed ID: 18407829
Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis.
Wüst S, van den Brandt J, Tischner D, Kleiman A, Tuckermann JP, Gold R, Lühder F, Reichardt HM
J Immunol. 2008
PubMed ID: 18523311
Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population.
Ikeda S, Sasazuki S, Natsukawa S, Shaura K, Koizumi Y, Kasuga Y, Ohnami S, Sakamoto H, Yoshida T, Iwasaki M, Tsugane S
Am J Gastroenterol. 2008
PubMed ID: 18510611
TotalPlex gene amplification using bulging primers for pharmacogenetic analysis of acute lymphoblastic leukemia.
Kang HJ, Oh Y, Chun SM, Seo YJ, Shin HY, Kim CW, Ahn HS, Han BD
Mol Cell Probes. 2008
PubMed ID: 18385010
Cross talk of signaling pathways in the regulation of the glucocorticoid receptor function.
Davies L, Karthikeyan N, Lynch JT, Sial EA, Gkourtsa A, Demonacos C, Krstic-Demonacos M
Mol Endocrinol. 2008
PubMed ID: 18337589
A common intron 2 polymorphism of the glucocorticoid receptor gene is associated with insulin resistance in men.
Syed AA, Halpin CG, Irving JA, Unwin NC, White M, Bhopal RS, Redfern CP, Weaver JU
Clin Endocrinol (Oxf). 2008
PubMed ID: 18194492
Activation of the glucocorticoid receptor releases unstimulated PBMCs from an early block in HIV-1 replication.
Wiegers K, Schwarck D, Reimer R, Bohn W
Virology. 2008
PubMed ID: 18295813
The novel gene AngRem104 downregulates glucocorticoid receptor expression and activates NF-kappaB in human mesangial cells.
Zhang Y, Zhang H, Hou P, Liang X, Li Z, Wang H
Biochem Biophys Res Commun. 2008
PubMed ID: 18331827
Progesterone receptor polymorphisms and risk of breast cancer: results from two Australian breast cancer studies.
Johnatty SE, Spurdle AB, Beesley J, Chen X, Hopper JL, Duffy DL, Chenevix-Trench G, The Kathleen Cuningham Consortium for Research in Familial Breast Cancer
Breast Cancer Res Treat. 2008
PubMed ID: 17592773
Glucocorticoid receptor variant and risk of dementia and white matter lesions.
van Rossum EF, de Jong FJ, Koper JW, Uitterlinden AG, Prins ND, van Dijk EJ, Koudstaal PJ, Hofman A, de Jong FH, Lamberts SW, Breteler MM
Neurobiol Aging. 2008
PubMed ID: 17184882
Glucocorticoid receptor gene polymorphisms and glucocorticoid sensitivity of subdermal blood vessels and leukocytes.
Kumsta R, Entringer S, Koper JW, van Rossum EF, Hellhammer DH, Wüst S
Biol Psychol. 2008
PubMed ID: 18502562
Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes.
So AY, Cooper SB, Feldman BJ, Manuchehri M, Yamamoto KR
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18408151
FMS-like tyrosine kinase 3 interacts with the glucocorticoid receptor complex and affects glucocorticoid dependent signaling.
Asadi A, Hedman E, Widén C, Zilliacus J, Gustafsson JA, Wikström AC
Biochem Biophys Res Commun. 2008
PubMed ID: 18261979
Genotype-phenotype correlation in a family with primary cortisol resistance: possible modulating effect of the ER22/23EK polymorphism.
Raef H, Baitei EY, Zou M, Shi Y
Eur J Endocrinol. 2008
PubMed ID: 18362306
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Transrepression function of the glucocorticoid receptor regulates eyelid development and keratinocyte proliferation but is not sufficient to prevent skin chronic inflammation.
Donet E, Bosch P, Sanchis A, Bayo P, Ramírez A, Cascallana JL, Bravo A, Pérez P
Mol Endocrinol. 2008
PubMed ID: 18174358
Cell density and serum exposure modify the function of the glucocorticoid receptor C/EBP complex.
Yang JQ, Rüdiger JJ, Hughes JM, Goulet S, Gencay-Cornelson MM, Borger P, Tamm M, Roth M
Am J Respir Cell Mol Biol. 2008
PubMed ID: 17989362
Interaction of the glucocorticoid receptor with the chromatin landscape.
John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, Voss TC, Davis SR, Meltzer PS, Stamatoyannopoulos JA, Hager GL
Mol Cell. 2008
PubMed ID: 18342607
Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses.
Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM
Epigenetics. 2008
PubMed ID: 18536531
A case of hypocortisolemic clinical Cushing's syndrome.
Al-Shoumer KA, Hafez MF, Doi SA
Ann Saudi Med. 2008
PubMed ID: 18398271
Glucocorticoid receptor gene polymorphisms in premenopausal women with major depression.
Krishnamurthy P, Romagni P, Torvik S, Gold PW, Charney DS, Detera-Wadleigh S, Cizza G, P.O.W.E.R. (Premenopausal, Osteoporosis Women, Alendronate, Depression) Study Group
Horm Metab Res. 2008
PubMed ID: 18246526
SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.
Han D, Jeon S, Sohn DH, Lee C, Ahn S, Kim WK, Chung H, Seong RH
Dev Biol. 2008
PubMed ID: 18206867
Stimulation of both type I and type II corticosteroid receptors blunts counterregulatory responses to subsequent hypoglycemia in healthy man.
Gustavson SM, Sandoval DA, Ertl AC, Bao S, Raj SR, Davis SN
Am J Physiol Endocrinol Metab. 2008
PubMed ID: 18182467
Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol.
Suino-Powell K, Xu Y, Zhang C, Tao YG, Tolbert WD, Simons SS, Xu HE
Mol Cell Biol. 2008
PubMed ID: 18160712
Glucocorticoid/glucocorticoid receptor inhibition of surfactant protein-A (SP-A) gene expression in lung type II cells is mediated by repressive changes in histone modification at the SP-A promoter.
Islam KN, Mendelson CR
Mol Endocrinol. 2008
PubMed ID: 18079322
Glucocorticoid receptor is required for skin barrier competence.
Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schütz G, Pérez P
Endocrinology. 2008
PubMed ID: 18039792
Toward a confocal subcellular atlas of the human proteome.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Mol Cell Proteomics. 2008
PubMed ID: 18029348
Unipolar depression and hippocampal volume: Impact of DNA sequence variants of the glucocorticoid receptor gene.
Zobel A, Jessen F, von Widdern O, Schuhmacher A, Höfels S, Metten M, Rietschel M, Scheef L, Block W, Becker T, Schild HH, Maier W, Schwab SG
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 18286599
Activated glucocorticoid receptor interacts with the INHAT component Set/TAF-Ibeta and releases it from a glucocorticoid-responsive gene promoter, relieving repression: implications for the pathogenesis of glucocorticoid resistance in acute undifferentiat
Ichijo T, Chrousos GP, Kino T
Mol Cell Endocrinol. 2008
PubMed ID: 18096310
The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus.
Ichihashi Y, Saito N, Arakawa Y, Kurata C, Iinuma M, Tamura Y, Iwaku F, Kubo KY
Okajimas Folia Anat Jpn. 2008
PubMed ID: 18464530
The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.
Trotter KW, Fan HY, Ivey ML, Kingston RE, Archer TK
Mol Cell Biol. 2008
PubMed ID: 18086889
Sex-specific association of the glucocorticoid receptor gene with extreme BMD.
Peng YM, Lei SF, Guo Y, Xiong DH, Yan H, Wang L, Guo YF, Deng HW
J Bone Miner Res. 2008
PubMed ID: 17937535
The relationship between cortisol, muscle mass and muscle strength in older persons and the role of genetic variations in the glucocorticoid receptor.
Peeters GM, van Schoor NM, van Rossum EF, Visser M, Lips P
Clin Endocrinol (Oxf). 2008
PubMed ID: 18248637
Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis.
Pearce CL, Wu AH, Gayther SA, Bale AE, Australian Cancer Study (Ovarian Cancer) and Australian Cancer Study Group, Beck PA, Beesley J, Chanock S, Cramer DW, DiCioccio R, Edwards R, Fredericksen ZS, Garcia-Closas M, Goode EL, Green AC, Hartmann LC, Hogdall E, Kjaer SK, Lissowska J, McGuire V, Modugno F, Moysich K, Ness RB, Ramus SJ, Risch HA, Sellers TA, Song H, Stram DO, Terry KL, Webb PM, Whiteman DC, Whittemore AS, Zheng W, Pharoah PD, Chenevix-Trench G, Pike MC, Schildkraut J, Berchuck A, Ovarian Cancer Association Consortium
Br J Cancer. 2008
PubMed ID: 18219286
Glucocorticoid receptor gene and risk of cardiovascular disease.
van den Akker EL, Koper JW, van Rossum EF, Dekker MJ, Russcher H, de Jong FH, Uitterlinden AG, Hofman A, Pols HA, Witteman JC, Lamberts SW
Arch Intern Med. 2008
PubMed ID: 18195193
A 5-year follow-up study of 3 polymorphisms in the human glucocorticoid receptor gene in relation to obesity, hypertension, and diabetes.
Rosmond R, Holm G
J Cardiometab Syndr. 2008
PubMed ID: 18983327
Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production.
Gumy C, Chandsawangbhuwana C, Dzyakanchuk AA, Kratschmar DV, Baker ME, Odermatt A
PLoS ONE. 2008
PubMed ID: 18958157
Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants.
Velez DR, Fortunato SJ, Thorsen P, Lombardi SJ, Williams SM, Menon R
PLoS ONE. 2008
PubMed ID: 18818748
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.
Skibola CF, Bracci PM, Halperin E, Nieters A, Hubbard A, Paynter RA, Skibola DR, Agana L, Becker N, Tressler P, Forrest MS, Sankararaman S, Conde L, Holly EA, Smith MT
PLoS ONE. 2008
PubMed ID: 18636124
Changes of glucocorticoid receptor expression in the nasal polyps of patients with chronic sinusitis following treatment with glucocorticoid.
Watanabe S, Suzaki H
In Vivo. 2008
PubMed ID: 18396779
Polymorphisms of the glucocorticoid receptor gene in Graves ophthalmopathy.
Boyle B, Korányi K, Patocs A, Liko I, Szappanos A, Bertalan R, Racz K, Balazs C
Br J Ophthalmol. 2008
PubMed ID: 18156379
The glucocorticoid receptor beta isoform can mediate transcriptional repression by recruiting histone deacetylases.
Kelly A, Bowen H, Jee YK, Mahfiche N, Soh C, Lee T, Hawrylowicz C, Lavender P
J Allergy Clin Immunol. 2008
PubMed ID: 18028994
Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.
Millien G, Beane J, Lenburg M, Tsao PN, Lu J, Spira A, Ramirez MI
Gene Expr Patterns. 2008
PubMed ID: 18023262
Glucocorticoid receptor changes its cellular location with breast cancer development.
Conde I, Paniagua R, Fraile B, Lucio J, Arenas MI
Histol Histopathol. 2008
PubMed ID: 17952860
Identification of novel glucocorticoid receptor-regulated genes involved in epidermal homeostasis and hair follicle differentiation.
Donet E, Bayo P, Calvo E, Labrie F, Pérez P
J Steroid Biochem Mol Biol. 2008
PubMed ID: 17935973
Abnormal urethra formation in mouse models of split-hand/split-foot malformation type 1 and type 4.
Suzuki K, Haraguchi R, Ogata T, Barbieri O, Alegria O, Vieux-Rochas M, Nakagata N, Ito M, Mills AA, Kurita T, Levi G, Yamada G
Eur J Hum Genet. 2008
PubMed ID: 17878916
Liver glucocorticoid receptor and heat shock protein 70 levels in rats exposed to different stress models.
Filipović D, Gavrilović L, Dronjak S, Demajo M, Radojcić MB
Physiol Res. 2008
PubMed ID: 17552876
An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells.
Dvorák Z, Vrzal R, Pávek P, Ulrichová J
Physiol Res. 2008
PubMed ID: 17552871
Alpha glucocorticoid receptor expression in different experimental rat models of acute lung injury.
Bertorelli G, Pesci A, Peveri S, Mergoni M, Corradi A, Maria Cantoni A, Tincani G, Bobbio A, Rusca M, Carbognani P
Pulm Pharmacol Ther. 2008
PubMed ID: 17467318
Endogenous glucocorticoids control neutrophil mobilization from bone marrow to blood and tissues in non-inflammatory conditions.
Cavalcanti DM, Lotufo CM, Borelli P, Ferreira ZS, Markus RP, Farsky SH
Br J Pharmacol. 2007
PubMed ID: 17982481
The 23K variant of the R23K polymorphism in the glucocorticoid receptor gene protects against postnatal growth failure and insulin resistance after preterm birth.
Finken MJ, Meulenbelt I, Dekker FW, Frölich M, Romijn JA, Slagboom PE, Wit JM, Dutch POPS-19 Collaborative Study Group
J Clin Endocrinol Metab. 2007
PubMed ID: 17848410
Serum fasting cortisol in relation to bone, and the role of genetic variations in the glucocorticoid receptor.
van Schoor NM, Dennison E, Lips P, Uitterlinden AG, Cooper C
Clin Endocrinol (Oxf). 2007
PubMed ID: 17681029
SIRT1 is involved in glucocorticoid-mediated control of uncoupling protein-3 gene transcription.
Amat R, Solanes G, Giralt M, Villarroya F
J Biol Chem. 2007
PubMed ID: 17884810
Identification of glucocorticoid-regulated genes that control cell proliferation during murine respiratory development.
Bird AD, Tan KH, Olsson PF, Zieba M, Flecknoe SJ, Liddicoat DR, Mollard R, Hooper SB, Cole TJ
J Physiol. 2007
PubMed ID: 17901120
Role of glucocorticoid receptor and CCAAT/enhancer-binding protein alpha in the feed-forward induction of 11beta-hydroxysteroid dehydrogenase type 1 expression by cortisol in human amnion fibroblasts.
Yang Z, Guo C, Zhu P, Li W, Myatt L, Sun K
J Endocrinol. 2007
PubMed ID: 17951535
Effect of the glucocorticoid receptor antagonist Org 34850 on basal and stress-induced corticosterone secretion.
Spiga F, Harrison LR, Wood SA, Atkinson HC, MacSweeney CP, Thomson F, Craighead M, Grassie M, Lightman SL
J Neuroendocrinol. 2007
PubMed ID: 17927667
Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone.
Conway-Campbell BL, McKenna MA, Wiles CC, Atkinson HC, de Kloet ER, Lightman SL
Endocrinology. 2007
PubMed ID: 17690167
Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor.
Gauer S, Segitz V, Goppelt-Struebe M
Nephrol Dial Transplant. 2007
PubMed ID: 17602195
Glucocorticoid receptor overexpression exerts an antisurvival effect on human small cell lung cancer cells.
Sommer P, Le Rouzic P, Gillingham H, Berry A, Kayahara M, Huynh T, White A, Ray DW
Oncogene. 2007
PubMed ID: 17496926
RIF-1, a novel nuclear receptor corepressor that associates with the nuclear matrix.
Li HJ, Haque ZK, Chen A, Mendelsohn M
J Cell Biochem. 2007
PubMed ID: 17455211
Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress.
Kumsta R, Entringer S, Koper JW, van Rossum EF, Hellhammer DH, Wüst S
Biol Psychiatry. 2007
PubMed ID: 17716631
Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor.
Lu NZ, Collins JB, Grissom SF, Cidlowski JA
Mol Cell Biol. 2007
PubMed ID: 17682054
A novel point mutation in helix 11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance.
Charmandari E, Kino T, Ichijo T, Jubiz W, Mejia L, Zachman K, Chrousos GP
J Clin Endocrinol Metab. 2007
PubMed ID: 17635946
Examination of Glucocorticoid receptor alpha-mediated transcriptional regulation of P-glycoprotein, CYP3A4, and CYP2C9 genes in placental trophoblast cell lines.
Pavek P, Cerveny L, Svecova L, Brysch M, Libra A, Vrzal R, Nachtigal P, Staud F, Ulrichova J, Fendrich Z, Dvorak Z
Placenta. 2007
PubMed ID: 17572486
Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block.
Sainte-Marie Y, Nguyen Dinh Cat A, Perrier R, Mangin L, Soukaseum C, Peuchmaur M, Tronche F, Farman N, Escoubet B, Benitah JP, Jaisser F
FASEB J. 2007
PubMed ID: 17517920
Progesterone, glucocorticoid, but not estrogen receptor mRNA is altered in breast cancer stroma.
Smith RA, Lea RA, Weinstein SR, Griffiths LR
Cancer Lett. 2007
PubMed ID: 17512111
Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B
J Infect Dis. 2007
PubMed ID: 17703412
Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats.
Mantsch JR, Cullinan WE, Tang LC, Baker DA, Katz ES, Hoks MA, Ziegler DR
Brain Res. 2007
PubMed ID: 17689506
Depletion of B cells in murine lupus: efficacy and resistance.
Ahuja A, Shupe J, Dunn R, Kashgarian M, Kehry MR, Shlomchik MJ
J Immunol. 2007
PubMed ID: 17709552
Transcription factors in muscle atrophy caused by blocked neuromuscular transmission and muscle unloading in rats.
Nordquist J, Höglund AS, Norman H, Tang X, Dworkin B, Larsson L
Mol Med. 2007
PubMed ID: 17622304
Glucocorticoid receptor gene polymorphisms and susceptibility to rheumatoid arthritis.
Donn R, Payne D, Ray D
Clin Endocrinol (Oxf). 2007
PubMed ID: 17532759
Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction.
Wei Q, Hebda-Bauer EK, Pletsch A, Luo J, Hoversten MT, Osetek AJ, Evans SJ, Watson SJ, Seasholtz AF, Akil H
J Neurosci. 2007
PubMed ID: 17699665
PD98059 enhanced insulin, cytokine, and growth factor activation of xanthine oxidoreductase in epithelial cells involves STAT3 and the glucocorticoid receptor.
Roberts LE, Fini MA, Derkash N, Wright RM
J Cell Biochem. 2007
PubMed ID: 17370312
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model.
Kohda K, Harada K, Kato K, Hoshino A, Motohashi J, Yamaji T, Morinobu S, Matsuoka N, Kato N
Neuroscience. 2007
PubMed ID: 17644267
MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.
Lee HK, Park UH, Kim EJ, Um SJ
EMBO J. 2007
PubMed ID: 17641689
Molecular evidence for a link between the N363S glucocorticoid receptor polymorphism and altered gene expression.
Jewell CM, Cidlowski JA
J Clin Endocrinol Metab. 2007
PubMed ID: 17535992
Gene-drug interaction at the glucocorticoid receptor increases risk of squamous cell skin cancer.
Patel AS, Karagas MR, Perry AE, Spencer SK, Nelson HH
J Invest Dermatol. 2007
PubMed ID: 17392827
A multipotent progenitor domain guides pancreatic organogenesis.
Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA
Dev Cell. 2007
PubMed ID: 17609113
Bombesin attenuates pre-mRNA splicing of glucocorticoid receptor by regulating the expression of serine-arginine protein p30c (SRp30c) in prostate cancer cells.
Zhu J, Gong JY, Goodman OB, Cartegni L, Nanus DM, Shen R
Biochim Biophys Acta. 2007
PubMed ID: 17540466
Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription.
Kinyamu HK, Archer TK
Mol Cell Biol. 2007
PubMed ID: 17438138
Correlation between glucocorticoid receptor binding parameters, blood pressure, and body mass index in a healthy human population.
Elaković I, Perisić T, Canković-Kadijević M, Matić G
Cell Biochem Funct. 2007
PubMed ID: 16615046
Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor.
So AY, Chaivorapol C, Bolton EC, Li H, Yamamoto KR
PLoS Genet. 2007
PubMed ID: 17559307
Changes of cytosol glucocorticoid receptor and renal Na(+)-K(+)-ATPase activity after swimming training in rat.
Peijie B, Zicai D, Tian W
J Sports Med Phys Fitness. 2007
PubMed ID: 17557067
Unfavorable socioeconomic conditions in early life presage expression of proinflammatory phenotype in adolescence.
Miller G, Chen E
Psychosom Med. 2007
PubMed ID: 17556642
cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis.
Lovgren AK, Kovarova M, Koller BH
Mol Cell Biol. 2007
PubMed ID: 17438133
Corticosteroid receptor-mediated mechanisms in the amygdala regulate anxiety and colonic sensitivity.
Myers B, Greenwood-Van Meerveld B
Am J Physiol Gastrointest Liver Physiol. 2007
PubMed ID: 17347454
Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors.
Kuningas M, de Rijk RH, Westendorp RG, Jolles J, Slagboom PE, van Heemst D
Neuropsychopharmacology. 2007
PubMed ID: 17133261
Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor.
Leung KW, Leung FP, Huang Y, Mak NK, Wong RN
FEBS Lett. 2007
PubMed ID: 17490654
Extracellular matrix-regulated gene expression requires cooperation of SWI/SNF and transcription factors.
Xu R, Spencer VA, Bissell MJ
J Biol Chem. 2007
PubMed ID: 17387179
Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression.
Engblom D, Kornfeld JW, Schwake L, Tronche F, Reimann A, Beug H, Hennighausen L, Moriggl R, Schütz G
Genes Dev. 2007
PubMed ID: 17504935
Macrophage glucocorticoid receptors regulate Toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase.
Bhattacharyya S, Brown DE, Brewer JA, Vogt SK, Muglia LJ
Blood. 2007
PubMed ID: 17255352
Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells.
Sohn KC, Jang S, Choi DK, Lee YS, Yoon TJ, Jeon EK, Kim KH, Seo YJ, Lee JH, Park JK, Kim CD
Biochem Biophys Res Commun. 2007
PubMed ID: 17382897
A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.
Ricketson D, Hostick U, Fang L, Yamamoto KR, Darimont BD
J Mol Biol. 2007
PubMed ID: 17367809
Recruitment of the p160 coactivators by the glucocorticoid receptor: dependence on the promoter context and cell type but not hypoxic conditions.
Trousson A, Grenier J, Fonte C, Massaad-Massade L, Schumacher M, Massaad C
J Steroid Biochem Mol Biol. 2007
PubMed ID: 17481888
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy.
Tuckermann JP, Kleiman A, Moriggl R, Spanbroek R, Neumann A, Illing A, Clausen BE, Stride B, Förster I, Habenicht AJ, Reichardt HM, Tronche F, Schmid W, Schütz G
J Clin Invest. 2007
PubMed ID: 17446934
Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.
van Winsen LM, Hooper-van Veen T, van Rossum EF, Koper JW, Barkhof F, Polman CH, Uitdehaag BM
J Neuroimmunol. 2007
PubMed ID: 17395275
Uteroplacental insufficiency alters nephrogenesis and downregulates cyclooxygenase-2 expression in a model of IUGR with adult-onset hypertension.
Baserga M, Hale MA, Wang ZM, Yu X, Callaway CW, McKnight RA, Lane RH
Am J Physiol Regul Integr Comp Physiol. 2007
PubMed ID: 17272666
[Effects of electromagnetic irradiation on glucocorticoid in serum and its receptor expression in rat hippocampus].
Li MQ, Wang YY, Zhang GB, Yu ZP
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007
PubMed ID: 17535653
Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis.
Olesen C, Nyeng P, Kalisz M, Jensen TH, Møller M, Tommerup N, Byskov AG
Cell Tissue Res. 2007
PubMed ID: 17431699
Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy.
Han F, Ozawa H, Matsuda KI, Lu H, De Kloet ER, Kawata M
J Neuroendocrinol. 2007
PubMed ID: 17244200
Expression and significance of glucocorticoid receptor alpha in meningiomas.
Zhao X, Teng LZ, Wang ZG, Xin T, Wei SC
J Clin Neurosci. 2007
PubMed ID: 17236775
The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction.
Liberman AC, Refojo D, Druker J, Toscano M, Rein T, Holsboer F, Arzt E
FASEB J. 2007
PubMed ID: 17215482
Chromatin-dependent cooperativity between site-specific transcription factors in vivo.
Hebbar PB, Archer TK
J Biol Chem. 2007
PubMed ID: 17186943
Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice.
Rozeboom AM, Akil H, Seasholtz AF
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17360585
Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast.
Klotsman M, York TP, Pillai SG, Vargas-Irwin C, Sharma SS, van den Oord EJ, Anderson WH
Pharmacogenet Genomics. 2007
PubMed ID: 17460547
Association between the BclI glucocorticoid receptor polymorphism and smoking in a sample of patients with obstructive airway disease.
Rogausch A, Kochen MM, Meineke C, Hennig J
Addict Biol. 2007
PubMed ID: 17407502
The modulation of STAT5A/GR complexes during fat cell differentiation and in mature adipocytes.
Baugh JE, Floyd ZE, Stephens JM
Obesity (Silver Spring). 2007
PubMed ID: 17372307
Enhanced glucocorticoid receptor signaling in T cells impacts thymocyte apoptosis and adaptive immune responses.
van den Brandt J, Lühder F, McPherson KG, de Graaf KL, Tischner D, Wiehr S, Herrmann T, Weissert R, Gold R, Reichardt HM
Am J Pathol. 2007
PubMed ID: 17322387
Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance.
Zinker B, Mika A, Nguyen P, Wilcox D, Ohman L, von Geldern TW, Opgenorth T, Jacobson P
Metabolism. 2007
PubMed ID: 17292727
Mechanism of histone H1-stimulated glucocorticoid receptor DNA binding in vivo.
Belikov S, Astrand C, Wrange O
Mol Cell Biol. 2007
PubMed ID: 17210632
Differential regulation of neurotrophins and serotonergic function in mice with genetically reduced glucocorticoid receptor expression.
Schulte-Herbrüggen O, Hellweg R, Chourbaji S, Ridder S, Brandwein C, Gass P, Hörtnagl H
Exp Neurol. 2007
PubMed ID: 17208231
Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase.
Wang Z, Chen W, Kono E, Dang T, Garabedian MJ
Mol Endocrinol. 2007
PubMed ID: 17185395
Glucocorticoid receptor polymorphisms and haplotypes associated with chronic fatigue syndrome.
Rajeevan MS, Smith AK, Dimulescu I, Unger ER, Vernon SD, Heim C, Reeves WC
Genes Brain Behav. 2007
PubMed ID: 16740143
Analysis of intranuclear binding process of glucocorticoid receptor using fluorescence correlation spectroscopy.
Mikuni S, Tamura M, Kinjo M
FEBS Lett. 2007
PubMed ID: 17239375
[Expression of glucocorticoid receptor alpha and beta in chronic rhinosinusitis with nasal polyp].
Wang MM, Zhang HP, Wang Z, Chen XM, Zhang DL
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007
PubMed ID: 17633260
[Glucocorticoid receptor subunit expression in adenoid tissue of children with obstructive sleep apnea hypopnea syndrome].
Zhang XW, Li Y, Xie MQ, Zhang GH, Liu X, Wang ZL, Wang T, Li ZH
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007
PubMed ID: 17633252
Associations between promoter usage and alternative splicing of the glucocorticoid receptor gene.
Russcher H, Dalm VA, de Jong FH, Brinkmann AO, Hofland LJ, Lamberts SW, Koper JW
J Mol Endocrinol. 2007
PubMed ID: 17242172
Identification, tissue expression, and glucocorticoid responsiveness of alternative first exons of the human glucocorticoid receptor.
Presul E, Schmidt S, Kofler R, Helmberg A
J Mol Endocrinol. 2007
PubMed ID: 17242171
STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression.
He Y, Simons SS
Mol Cell Biol. 2007
PubMed ID: 17116691
Glucocorticoid receptor beta splice variant expression in patients with high and low activity of systemic lupus erythematosus.
Piotrowski P, Burzynski M, Lianeri M, Mostowska M, Wudarski M, Chwalinska-Sadowska H, Jagodzinski PP
Folia Histochem Cytobiol. 2007
PubMed ID: 18165172
Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis.
Corvol H, Nathan N, Charlier C, Chadelat K, Le Rouzic P, Tabary O, Fauroux B, Henrion-Caude A, Feingold J, Boelle PY, Clement A
Respir Res. 2007
PubMed ID: 18047640
The full-ORF clone resource of the German cDNA Consortium.
Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blöcker H, Heubner D, Hoerlein A, Michel G, Wedler H, Köhrer K, Ottenwälder B, Poustka A, Wiemann S, Schupp I
BMC Genomics. 2007
PubMed ID: 17974005
The glucocorticoid receptor gene exon 1-F promoter is not methylated at the NGFI-A binding site in human hippocampus.
Moser D, Molitor A, Kumsta R, Tatschner T, Riederer P, Meyer J
World J Biol Psychiatry. 2007
PubMed ID: 17853270
The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation.
Chen W, Roeder RG
Nucleic Acids Res. 2007
PubMed ID: 17827210
Genetic association of a polymorphism of the cAMP-responsive element binding protein-binding protein with steroid-induced osteonecrosis after kidney transplantation.
Tamura K, Nakajima S, Hirota Y, Takahashi KA, Fujioka M, Kubo T, Iwatani Y, Ozono K
J Bone Miner Metab. 2007
PubMed ID: 17704997
Inducible gene inactivation in neurons of the adult mouse forebrain.
Erdmann G, Schütz G, Berger S
BMC Neurosci. 2007
PubMed ID: 17683525
The variant N363S of glucocorticoid receptor in steroid-induced ocular hypertension in Hungarian patients treated with photorefractive keratectomy.
Szabó V, Borgulya G, Filkorn T, Majnik J, Bányász I, Nagy ZZ
Mol Vis. 2007
PubMed ID: 17563720
Association of progesterone receptor gene polymorphism (PROGINS) with endometriosis, uterine fibroids and breast cancer.
Govindan S, Ahmad SN, Vedicherla B, Kodati V, Jahan P, Rao KP, Ahuja YR, Hasan Q
Cancer Biomark. 2007
PubMed ID: 17522428
[Expression of glucocorticoid receptor alpha and beta mRNA in orbital tissues in thyroid associated ophthalmopathy].
Luo QL, He WM, Xia QJ, Cao GQ, Yan NH, Wang L, Zhang FQ
Zhonghua Yan Ke Za Zhi. 2007
PubMed ID: 17442162
A new transcript splice variant of the human glucocorticoid receptor: identification and tissue distribution of hGR Delta 313-338, an alternative exon 2 transactivation domain isoform.
Turner JD, Schote AB, Keipes M, Muller CP
Ann N Y Acad Sci. 2007
PubMed ID: 17404046
Glucocorticoid receptor expression in the cortex of the neonatal rat brain with and without focal cerebral ischemia.
Lee BH, Wen TC, Rogido M, Sola A
Neonatology. 2007
PubMed ID: 17344647
Progesterone receptor (PROGINS) polymorphism and the risk of endometrial cancer development.
Junqueira MG, da Silva ID, Nogueira-de-Souza NC, Carvalho CV, Leite DB, Gomes MT, Baracat EC, Lopes LA, Nicolau SM, Gonçalves WJ
Int J Gynecol Cancer. 2007
PubMed ID: 17291258
Expression of Cre recombinase in dopaminoceptive neurons.
Lemberger T, Parlato R, Dassesse D, Westphal M, Casanova E, Turiault M, Tronche F, Schiffmann SN, Schütz G
BMC Neurosci. 2007
PubMed ID: 17201924
Interaction of rat renal glucocorticoid receptor with Hsp90 and Hsp70 upon stress provoked by mercury.
Brkljacić J, Perisić T, Dundjerski J, Matić G
J Appl Toxicol. 2007
PubMed ID: 17177174
Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells.
Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP
Mol Endocrinol. 2007
PubMed ID: 16973758
Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor.
Wang D, Zhang H, Lang F, Yun CC
Am J Physiol Cell Physiol. 2007
PubMed ID: 16971495
Role of glucocorticoid receptor gene in vulnerability for major depression: commentary on Neigh and Nemeroff.
Van Den Eede F, van West D, Van Broeckhoven C, Claes SJ
Trends Endocrinol Metab. 2006
PubMed ID: 17070695
Spatial and temporal expression of glucocorticoid, retinoid, and thyroid hormone receptors is not altered in lungs of congenital diaphragmatic hernia.
Rajatapiti P, Keijzer R, Blommaart PE, Lamers WH, DE Krijger RR, Visser TJ, Tibboel D, Rottier R
Pediatr Res. 2006
PubMed ID: 17065567
Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells.
Tao T, Lan J, Lukacs GL, Haché RJ, Kaplan F
Am J Respir Cell Mol Biol. 2006
PubMed ID: 16809634
Stress-resistant mice overexpressing glucocorticoid receptors display enhanced BDNF in the amygdala and hippocampus with unchanged NGF and serotonergic function.
Schulte-Herbrüggen O, Chourbaji S, Ridder S, Brandwein C, Gass P, Hörtnagl H, Hellweg R
Psychoneuroendocrinology. 2006
PubMed ID: 17098367
A polymorphic glucocorticoid receptor in a mouse population may explain inherited altered stress response and increased anxiety-type behaviors.
Xu D, Buehner A, Xu J, Lambert T, Nekl C, Nielsen MK, Zhou Y
FASEB J. 2006
PubMed ID: 17012242
Associations of body size at birth with late-life cortisol concentrations and glucose tolerance are modified by haplotypes of the glucocorticoid receptor gene.
Rautanen A, Eriksson JG, Kere J, Andersson S, Osmond C, Tienari P, Sairanen H, Barker DJ, Phillips DI, Forsén T, Kajantie E
J Clin Endocrinol Metab. 2006
PubMed ID: 16895953
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.
Bilodeau S, Vallette-Kasic S, Gauthier Y, Figarella-Branger D, Brue T, Berthelet F, Lacroix A, Batista D, Stratakis C, Hanson J, Meij B, Drouin J
Genes Dev. 2006
PubMed ID: 17043312
The glucocorticoid receptor N363S polymorphism and steroid response in Duchenne dystrophy.
Bonifati DM, Witchel SF, Ermani M, Hoffman EP, Angelini C, Pegoraro E
J Neurol Neurosurg Psychiatry. 2006
PubMed ID: 16980656
A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA
Development. 2006
PubMed ID: 16971476
Functional analysis of the LXXLL motifs of the human glucocorticoid receptor: association with altered ligand affinity.
Dong DD, Jewell CM, Bienstock RJ, Cidlowski JA
J Steroid Biochem Mol Biol. 2006
PubMed ID: 16914312
Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN.
Löwenberg M, Verhaar AP, Bilderbeek J, Marle J, Buttgereit F, Peppelenbosch MP, van Deventer SJ, Hommes DW
EMBO Rep. 2006
PubMed ID: 16888650
A functional polymorphism in the glucocorticoid receptor gene and its relation to cardiovascular disease risk in familial hypercholesterolemia.
Koeijvoets KC, van Rossum EF, Dallinga-Thie GM, Steyerberg EW, Defesche JC, Kastelein JJ, Lamberts SW, Sijbrands EJ
J Clin Endocrinol Metab. 2006
PubMed ID: 16849409
Genetic variations of the NR3C1 gene in children with sporadic nephrotic syndrome.
Ye J, Yu Z, Ding J, Chen Y, Huang J, Yao Y, Xiao H, Yang J, Shen Y, Meng Q
Biochem Biophys Res Commun. 2006
PubMed ID: 16890204
Cellular co-localization of protein phosphatase 5 and glucocorticoid receptors in rat brain.
Rossie S, Jayachandran H, Meisel RL
Brain Res. 2006
PubMed ID: 16899232
Glucocorticoid receptor expression in advanced non-small cell lung cancer: clinicopathological correlation and in vitro effect of glucocorticoid on cell growth and chemosensitivity.
Lu YS, Lien HC, Yeh PY, Kuo SH, Chang WC, Kuo ML, Cheng AL
Lung Cancer. 2006
PubMed ID: 16806572
Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors.
Herrero AI, Sandi C, Venero C
Neurobiol Learn Mem. 2006
PubMed ID: 16580234
Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.
Abraham SM, Lawrence T, Kleiman A, Warden P, Medghalchi M, Tuckermann J, Saklatvala J, Clark AR
J Exp Med. 2006
PubMed ID: 16880258
Glucocorticoids suppress bone formation via the osteoclast.
Kim HJ, Zhao H, Kitaura H, Bhattacharyya S, Brewer JA, Muglia LJ, Ross FP, Teitelbaum SL
J Clin Invest. 2006
PubMed ID: 16878176
Detection of the Bcl I polymorphism of the glucocorticoid receptor gene by single-tube allele-specific polymerase chain reaction.
Gergics P, Patocs A, Majnik J, Balogh K, Szappanos A, Toth M, Racz K
J Steroid Biochem Mol Biol. 2006
PubMed ID: 16806906
Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study.
Kuningas M, Mooijaart SP, Slagboom PE, Westendorp RG, van Heemst D
Biogerontology. 2006
PubMed ID: 16676134
Glucocorticoid receptor polymorphism affects transrepression but not transactivation.
van den Akker EL, Russcher H, van Rossum EF, Brinkmann AO, de Jong FH, Hokken A, Pols HA, Koper JW, Lamberts SW
J Clin Endocrinol Metab. 2006
PubMed ID: 16684836
Overrepresentation of the N363S variant of the glucocorticoid receptor gene in patients with bilateral adrenal incidentalomas.
Majnik J, Patocs A, Balogh K, Toth M, Gergics P, Szappanos A, Mondok A, Borgulya G, Panczel P, Prohaszka Z, Racz K
J Clin Endocrinol Metab. 2006
PubMed ID: 16636127
Altered glucocorticoid receptor signaling cascade in lymphocytes of bipolar disorder patients.
Spiliotaki M, Salpeas V, Malitas P, Alevizos V, Moutsatsou P
Psychoneuroendocrinology. 2006
PubMed ID: 16621324
Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling.
Löwenberg M, Tuynman J, Scheffer M, Verhaar A, Vermeulen L, van Deventer S, Hommes D, Peppelenbosch M
Endocrinology. 2006
PubMed ID: 16574792
The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-beta-catenin complex.
Takayama S, Rogatsky I, Schwarcz LE, Darimont BD
J Biol Chem. 2006
PubMed ID: 16644723
ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5.
Saelzler MP, Spackman CC, Liu Y, Martinez LC, Harris JP, Abe MK
J Biol Chem. 2006
PubMed ID: 16624805
HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription.
Qiu Y, Zhao Y, Becker M, John S, Parekh BS, Huang S, Hendarwanto A, Martinez ED, Chen Y, Lu H, Adkins NL, Stavreva DA, Wiench M, Georgel PT, Schiltz RL, Hager GL
Mol Cell. 2006
PubMed ID: 16762839
Potential advantage of N363S glucocorticoid receptor polymorphism in 21-hydroxylase deficiency.
Luczay A, Török D, Ferenczi A, Majnik J, Sólyom J, Fekete G
Eur J Endocrinol. 2006
PubMed ID: 16728546
Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors.
Marom R, Shur I, Hager GL, Benayahu D
J Cell Physiol. 2006
PubMed ID: 16523501
Activation function 1 of glucocorticoid receptor binds TATA-binding protein in vitro and in vivo.
Copik AJ, Webb MS, Miller AL, Wang Y, Kumar R, Thompson EB
Mol Endocrinol. 2006
PubMed ID: 16469772
Association of glucocorticoid receptor polymorphism A3669G in exon 9beta with reduced central adiposity in women.
Syed AA, Irving JA, Redfern CP, Hall AG, Unwin NC, White M, Bhopal RS, Weaver JU
Obesity (Silver Spring). 2006
PubMed ID: 16855182
Proteomic identification of glucocorticoid receptor interacting proteins.
Hedman E, Widén C, Asadi A, Dinnetz I, Schröder WP, Gustafsson JA, Wikström AC
Proteomics. 2006
PubMed ID: 16619302
Maturation and maintenance of cholinergic medial septum neurons require glucocorticoid receptor signaling.
Guijarro C, Rutz S, Rothmaier K, Turiault M, Zhi Q, Naumann T, Frotscher M, Tronche F, Jackisch R, Kretz O
J Neurochem. 2006
PubMed ID: 16573657
Role of steroid receptor coactivators in glucocorticoid and transforming growth factor beta regulation of plasminogen activator inhibitor gene expression.
Li G, Heaton JH, Gelehrter TD
Mol Endocrinol. 2006
PubMed ID: 16423881
Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer.
Damaraju S, Murray D, Dufour J, Carandang D, Myrehaug S, Fallone G, Field C, Greiner R, Hanson J, Cass CE, Parliament M
Clin Cancer Res. 2006
PubMed ID: 16638864
Polymorphisms of the glucocorticoid receptor gene and major depression.
van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, Modell S, Salyakina D, Lamberts SW, Holsboer F
Biol Psychiatry. 2006
PubMed ID: 16580345
Reduced Glucocorticoid Receptor alpha Expression in Mood Disorder Patients and First-Degree Relatives.
Matsubara T, Funato H, Kobayashi A, Nobumoto M, Watanabe Y
Biol Psychiatry. 2006
PubMed ID: 16458268
Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle.
Yao Z, DuBois DC, Almon RR, Jusko WJ
Pharm Res. 2006
PubMed ID: 16673181
Combinations of single nucleotide polymorphisms in neuroendocrine effector and receptor genes predict chronic fatigue syndrome.
Goertzel BN, Pennachin C, de Souza Coelho L, Gurbaxani B, Maloney EM, Jones JF
Pharmacogenomics. 2006
PubMed ID: 16610957
Polymorphisms in genes regulating the HPA axis associated with empirically delineated classes of unexplained chronic fatigue.
Smith AK, White PD, Aslakson E, Vollmer-Conna U, Rajeevan MS
Pharmacogenomics. 2006
PubMed ID: 16610949
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Modeling glucocorticoid-mediated fetal lung maturation: II. Temporal patterns of gene expression in fetal rat lung.
Samtani MN, Pyszczynski NA, Dubois DC, Almon RR, Jusko WJ
J Pharmacol Exp Ther. 2006
PubMed ID: 16371448
Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity.
Son GH, Geum D, Chung S, Kim EJ, Jo JH, Kim CM, Lee KH, Kim H, Choi S, Kim HT, Lee CJ, Kim K
J Neurosci. 2006
PubMed ID: 16554481
Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma.
Goleva E, Li LB, Eves PT, Strand MJ, Martin RJ, Leung DY
Am J Respir Crit Care Med. 2006
PubMed ID: 16387802
[Investigation of GR mRNA quantu expression in chronic sinusitis and nasal polyps].
Li P, Li Y, Liu X, Ye J, Wang ZL, Li YQ, Hu B
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2006
PubMed ID: 16759008
Insulin modulates rat liver glucocorticoid receptor.
Isenovic ER, Zakula Z, Koricanac G, Ribarac-Stepic N
Acta Biol Hung. 2006
PubMed ID: 16646523
GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway.
Chadli A, Graham JD, Abel MG, Jackson TA, Gordon DF, Wood WM, Felts SJ, Horwitz KB, Toft D
Mol Cell Biol. 2006
PubMed ID: 16478993
MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor.
Chen W, Rogatsky I, Garabedian MJ
Mol Endocrinol. 2006
PubMed ID: 16239257
Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.
van West D, Van Den Eede F, Del-Favero J, Souery D, Norrback KF, Van Duijn C, Sluijs S, Adolfsson R, Mendlewicz J, Deboutte D, Van Broeckhoven C, Claes S
Neuropsychopharmacology. 2006
PubMed ID: 16192984
Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness.
Boyle MP, Kolber BJ, Vogt SK, Wozniak DF, Muglia LJ
J Neurosci. 2006
PubMed ID: 16481429
Association study of six activity SNPS in adrenal steroid hormone metabolism and IBM related genes with precocious puberty in Chinese girls.
Xin X, Xiao J, Luan X, Zhou Y, Lu D, Wei D, Yang S
Neuro Endocrinol Lett. 2006
PubMed ID: 16648810
The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1.
Muthumani K, Choo AY, Zong WX, Madesh M, Hwang DS, Premkumar A, Thieu KP, Emmanuel J, Kumar S, Thompson CB, Weiner DB
Nat Cell Biol. 2006
PubMed ID: 16429131
Glucocorticoids engage different signal transduction pathways to induce apoptosis in thymocytes and mature T cells.
Wang D, Müller N, McPherson KG, Reichardt HM
J Immunol. 2006
PubMed ID: 16424199
Gene expression regulation following behavioral sensitization to cocaine in transgenic mice lacking the glucocorticoid receptor in the brain.
Izawa R, Jaber M, Deroche-Gamonet V, Sillaber I, Kellendonk C, Le Moal M, Tronche F, Piazza PV
Neuroscience. 2006
PubMed ID: 16326019
Medroxyprogesterone acetate binds the glucocorticoid receptor to stimulate alpha-ENaC and sgk1 expression in renal collecting duct epithelia.
Thomas CP, Liu KZ, Vats HS
Am J Physiol Renal Physiol. 2006
PubMed ID: 16189295
Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis.
Sionov RV, Cohen O, Kfir S, Zilberman Y, Yefenof E
J Exp Med. 2006
PubMed ID: 16390935
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression.
Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, Adcock IM
J Exp Med. 2006
PubMed ID: 16380507
The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression.
Reily MM, Pantoja C, Hu X, Chinenov Y, Rogatsky I
EMBO J. 2006
PubMed ID: 16362036
ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis.
Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA
Cell Oncol. 2006
PubMed ID: 17167179
Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens.
Dong Z, Han H, Wang M, Xu L, Hao W, Cao J
Hippocampus. 2006
PubMed ID: 16897719
Evidence denies the presence of O-GlcNAcylation on mouse glucocorticoid receptor and its potential involvement in receptor transcriptional activity.
Zhang S, Danielsen M
J Recept Signal Transduct Res. 2006
PubMed ID: 16777711
Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity.
Marti A, Ochoa MC, Sánchez-Villegas A, Martínez JA, Martínez-González MA, Hebebrand J, Hinney A, Vedder H
BMC Med Genet. 2006
PubMed ID: 16725041
Chaperoning of glucocorticoid receptors.
Pratt WB, Morishima Y, Murphy M, Harrell M
Handb Exp Pharmacol. 2006
PubMed ID: 16610357
Expression of the glucocorticoid receptor in the human adrenal cortex.
Paust HJ, Loeper S, Else T, Bamberger AM, Papadopoulos G, Pankoke D, Saeger W, Bamberger CM
Exp Clin Endocrinol Diabetes. 2006
PubMed ID: 16450310
Glucocorticoid receptor beta in acute and chronic inflammatory conditions: clinical implications.
Goecke A, Guerrero J
Immunobiology. 2006
PubMed ID: 16446173
Glucocorticoid receptor regulates ATP-binding cassette transporter-A1 expression and apolipoprotein-mediated cholesterol efflux from macrophages.
Ayaori M, Sawada S, Yonemura A, Iwamoto N, Ogura M, Tanaka N, Nakaya K, Kusuhara M, Nakamura H, Ohsuzu F
Arterioscler Thromb Vasc Biol. 2006
PubMed ID: 16254209
c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter.
Geng CD, Vedeckis WV
J Biol Chem. 2005
PubMed ID: 16263717
Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone.
Karst H, Berger S, Turiault M, Tronche F, Schütz G, Joëls M
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16361444
Ligand-specific glucocorticoid receptor activation in human platelets.
Moraes LA, Paul-Clark MJ, Rickman A, Flower RJ, Goulding NJ, Perretti M
Blood. 2005
PubMed ID: 16131566
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.
Guo D, Han J, Adam BL, Colburn NH, Wang MH, Dong Z, Eizirik DL, She JX, Wang CY
Biochem Biophys Res Commun. 2005
PubMed ID: 16236267
Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor.
Lim G, Wang S, Zeng Q, Sung B, Yang L, Mao J
J Neurosci. 2005
PubMed ID: 16319314
Macromolecular translocation inhibitor II (Zn(2+)-binding protein, parathymosin) interacts with the glucocorticoid receptor and enhances transcription in vivo.
Okamoto K, Isohashi F
J Biol Chem. 2005
PubMed ID: 16150697
[Changes in glucocorticoid receptor and heat shock protein 70 in liver tissue after trauma with hemorrhagic shock in rats]
Luo DL, Zhou JH, Liu BH, Xiong RP, Ye XF, Xu X, Chen JP
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005
PubMed ID: 16297316
Central glucocorticoid receptors modulate the expression of spinal cannabinoid receptors induced by chronic morphine exposure.
Lim G, Wang S, Mao J
Brain Res. 2005
PubMed ID: 16150424
Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone.
Murphy PJ, Morishima Y, Kovacs JJ, Yao TP, Pratt WB
J Biol Chem. 2005
PubMed ID: 16087666
Intracellular glucocorticoid signaling: a formerly simple system turns stochastic.
Chrousos GP, Kino T
Sci STKE. 2005
PubMed ID: 16204701
Structure of the glucocorticoid receptor (NR3C1) gene 5' untranslated region: identification, and tissue distribution of multiple new human exon 1.
Turner JD, Muller CP
J Mol Endocrinol. 2005
PubMed ID: 16216909
Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes.
Solá S, Amaral JD, Castro RE, Ramalho RM, Borralho PM, Kren BT, Tanaka H, Steer CJ, Rodrigues CM
Hepatology. 2005
PubMed ID: 16175607
The impact of glucocorticoid receptor gene polymorphisms on glucocorticoid sensitivity is outweighted in patients with multiple sclerosis.
van Winsen LL, Hooper-van Veen T, van Rossum EF, Polman CH, van den Berg TK, Koper JW, Uitdehaag BM
J Neuroimmunol. 2005
PubMed ID: 16083972
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.
Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK
Cell. 2005
PubMed ID: 16143103
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Corticosteroid binding globulin gene polymorphism influences cortisol driven fat distribution in obese women.
Barat P, Duclos M, Gatta B, Roger P, Mormede P, Moisan MP
Obes Res. 2005
PubMed ID: 16222046
Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA
Mol Pharmacol. 2005
PubMed ID: 15933212
Enduring, handling-evoked enhancement of hippocampal memory function and glucocorticoid receptor expression involves activation of the corticotropin-releasing factor type 1 receptor.
Fenoglio KA, Brunson KL, Avishai-Eliner S, Stone BA, Kapadia BJ, Baram TZ
Endocrinology. 2005
PubMed ID: 15932935
Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus.
Wong EY, Herbert J
Eur J Neurosci. 2005
PubMed ID: 16115202
Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation.
Crochemore C, Lu J, Wu Y, Liposits Z, Sousa N, Holsboer F, Almeida OF
Mol Psychiatry. 2005
PubMed ID: 15940303
Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism.
Muthumani K, Choo AY, Premkumar A, Hwang DS, Thieu KP, Desai BM, Weiner DB
Cell Death Differ. 2005
PubMed ID: 15832179
Glucocorticoid receptor point mutation V571M facilitates coactivator and ligand binding by structural rearrangement and stabilization.
Carlsson P, Koehler KF, Nilsson L
Mol Endocrinol. 2005
PubMed ID: 15774500
Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer.
Baumann S, Dostert A, Novac N, Bauer A, Schmid W, Fas SC, Krueger A, Heinzel T, Kirchhoff S, Schütz G, Krammer PH
Blood. 2005
PubMed ID: 15802531
Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice.
Liang Y, Osborne MC, Monia BP, Bhanot S, Watts LM, She P, DeCarlo SO, Chen X, Demarest K
Metabolism. 2005
PubMed ID: 15988691
Increased expression of the glucocorticoid receptor-A translational isoform as a result of the ER22/23EK polymorphism.
Russcher H, van Rossum EF, de Jong FH, Brinkmann AO, Lamberts SW, Koper JW
Mol Endocrinol. 2005
PubMed ID: 15746190
Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stress-induced depressive reactions.
Ridder S, Chourbaji S, Hellweg R, Urani A, Zacher C, Schmid W, Zink M, Hörtnagl H, Flor H, Henn FA, Schütz G, Gass P
J Neurosci. 2005
PubMed ID: 15987954
G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.
Kino T, Tiulpakov A, Ichijo T, Chheng L, Kozasa T, Chrousos GP
J Cell Biol. 2005
PubMed ID: 15955845
Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment.
Jee YK, Gilmour J, Kelly A, Bowen H, Richards D, Soh C, Smith P, Hawrylowicz C, Cousins D, Lee T, Lavender P
J Biol Chem. 2005
PubMed ID: 15826950
HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.
Shimizu N, Ouchida R, Yoshikawa N, Hisada T, Watanabe H, Okamoto K, Kusuhara M, Handa H, Morimoto C, Tanaka H
Proc Natl Acad Sci U S A. 2005
PubMed ID: 15941832
Increased expression of glucocorticoid receptor beta messenger RNA in patients with ankylosing spondylitis.
Lee CK, Lee EY, Cho YS, Moon KA, Yoo B, Moon HB
Korean J Intern Med. 2005
PubMed ID: 16134770
A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: the importance of the C terminus of hGR LBD in conferring transactivational activity.
Charmandari E, Raji A, Kino T, Ichijo T, Tiulpakov A, Zachman K, Chrousos GP
J Clin Endocrinol Metab. 2005
PubMed ID: 15769988
Alternative effects of the ubiquitin-proteasome pathway on glucocorticoid receptor down-regulation and transactivation are mediated by CHIP, an E3 ligase.
Wang X, DeFranco DB
Mol Endocrinol. 2005
PubMed ID: 15761032
The human glucocorticoid receptor (GR) isoform {beta} differentially suppresses GR{alpha}-induced transactivation stimulated by synthetic glucocorticoids.
Fruchter O, Kino T, Zoumakis E, Alesci S, De Martino M, Chrousos G, Hochberg Z
J Clin Endocrinol Metab. 2005
PubMed ID: 15755863
Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia.
Cascallana JL, Bravo A, Donet E, Leis H, Lara MF, Paramio JM, Jorcano JL, Pérez P
Endocrinology. 2005
PubMed ID: 15746257
Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo.
Pazirandeh A, Jondal M, Okret S
Endocrinology. 2005
PubMed ID: 15731366
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
Kovacs JJ, Murphy PJ, Gaillard S, Zhao X, Wu JT, Nicchitta CV, Yoshida M, Toft DO, Pratt WB, Yao TP
Mol Cell. 2005
PubMed ID: 15916966
Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: evidence for tissue- and cell type-specific functions.
Geng CD, Pedersen KB, Nunez BS, Vedeckis WV
Biochemistry. 2005
PubMed ID: 15895983
NRIP, a novel nuclear receptor interaction protein, enhances the transcriptional activity of nuclear receptors.
Tsai TC, Lee YL, Hsiao WC, Tsao YP, Chen SL
J Biol Chem. 2005
PubMed ID: 15784617
The pregnancy hormone relaxin binds to and activates the human glucocorticoid receptor.
Dschietzig T, Bartsch C, Greinwald M, Baumann G, Stangl K
Ann N Y Acad Sci. 2005
PubMed ID: 15956716
The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men.
Buemann B, Black E, Holst C, Toubro S, Echwald S, Pedersen O, Astrup A, Sørensen T
Obes Res. 2005
PubMed ID: 15919839
The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.
Luecke HF, Yamamoto KR
Genes Dev. 2005
PubMed ID: 15879558
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression.
Ki SH, Cho IJ, Choi DW, Kim SG
Mol Cell Biol. 2005
PubMed ID: 15870285
The human glucocorticoid receptor: one gene, multiple proteins and diverse responses.
Zhou J, Cidlowski JA
Steroids. 2005
PubMed ID: 15862824
The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids.
Revest JM, Di Blasi F, Kitchener P, Rougé-Pont F, Desmedt A, Turiault M, Tronche F, Piazza PV
Nat Neurosci. 2005
PubMed ID: 15834420
Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes.
Lu NZ, Cidlowski JA
Mol Cell. 2005
PubMed ID: 15866175
Conditional regulation of the human CYP4X1 and CYP4Z1 genes.
Savas U, Hsu MH, Griffin KJ, Bell DR, Johnson EF
Arch Biochem Biophys. 2005
PubMed ID: 15797250
GR and HMGB1 interact only within chromatin and influence each other's residence time.
Agresti A, Scaffidi P, Riva A, Caiolfa VR, Bianchi ME
Mol Cell. 2005
PubMed ID: 15808513
Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line.
Gaeggeler HP, Gonzalez-Rodriguez E, Jaeger NF, Loffing-Cueni D, Norregaard R, Loffing J, Horisberger JD, Rossier BC
J Am Soc Nephrol. 2005
PubMed ID: 15743993
Cytosolic glucocorticoid receptor expression in the rat vestibular nucleus and hippocampus following unilateral vestibular deafferentation.
Lindsay L, Liu P, Gliddon C, Zheng Y, Smith PF, Darlington CL
Exp Brain Res. 2005
PubMed ID: 15580339
Glucocorticoid receptor polymorphisms and post-traumatic stress disorder.
Bachmann AW, Sedgley TL, Jackson RV, Gibson JN, Young RM, Torpy DJ
Psychoneuroendocrinology. 2005
PubMed ID: 15511603
Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse.
Schmidt MV, Schmidt M, Levine S, Oitzl MS, van der Mark M, Müller MB, Holsboer F, de Kloet ER
Endocrinology. 2005
PubMed ID: 15591147
Interaction between the interferon signaling pathway and the human glucocorticoid receptor gene 1A promoter.
Nunez BS, Geng CD, Pedersen KB, Millro-Macklin CD, Vedeckis WV
Endocrinology. 2005
PubMed ID: 15576464
Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protei
Sugatani J, Nishitani S, Yamakawa K, Yoshinari K, Sueyoshi T, Negishi M, Miwa M
Mol Pharmacol. 2005
PubMed ID: 15557560
Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression.
Bladh LG, Lidén J, Dahlman-Wright K, Reimers M, Nilsson S, Okret S
Mol Pharmacol. 2005
PubMed ID: 15550679
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.
Wochnik GM, Rüegg J, Abel GA, Schmidt U, Holsboer F, Rein T
J Biol Chem. 2005
PubMed ID: 15591061
Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival.
Wu W, Pew T, Zou M, Pang D, Conzen SD
J Biol Chem. 2005
PubMed ID: 15590693
Novel genetic polymorphisms in the NR3C1 (glucocorticoid receptor) gene in a Japanese population.
Koyano S, Saito Y, Sai K, Kurose K, Ozawa S, Nakajima T, Matsumoto K, Saito H, Shirao K, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J
Drug Metab Pharmacokinet. 2005
PubMed ID: 15770078
Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1.
Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O'Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R
Tissue Antigens. 2005
PubMed ID: 15713213
Glucocorticoid receptor subunit expression in adenotonsillar tissue of children with obstructive sleep apnea.
Goldbart AD, Veling MC, Goldman JL, Li RC, Brittian KR, Gozal D
Pediatr Res. 2005
PubMed ID: 15611350
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
Albers M, Kranz H, Kober I, Kaiser C, Klink M, Suckow J, Kern R, Koegl M
Mol Cell Proteomics. 2005
PubMed ID: 15604093
Glucocorticoid receptor ligand binding domain is sufficient for the modulation of glucocorticoid induction properties by homologous receptors, coactivator transcription intermediary factor 2, and Ubc9.
Cho S, Kagan BL, Blackford JA, Szapary D, Simons SS
Mol Endocrinol. 2005
PubMed ID: 15539428
The epithelial glucocorticoid receptor is required for the normal timing of cell proliferation during mammary lobuloalveolar development but is dispensable for milk production.
Wintermantel TM, Bock D, Fleig V, Greiner EF, Schütz G
Mol Endocrinol. 2005
PubMed ID: 15471946
Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.
Nie M, Corbett L, Knox AJ, Pang L
J Biol Chem. 2005
PubMed ID: 15531761
Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior.
Boyle MP, Brewer JA, Funatsu M, Wozniak DF, Tsien JZ, Izumi Y, Muglia LJ
Proc Natl Acad Sci U S A. 2005
PubMed ID: 15623560
Visualization of glucocorticoid receptor in the brain of green fluorescent protein-glucocorticoid receptor knockin mice.
Usuku T, Nishi M, Morimoto M, Brewer JA, Muglia LJ, Sugimoto T, Kawata M
Neuroscience. 2005
PubMed ID: 16154291
The Vpr protein from HIV-1: distinct roles along the viral life cycle.
Le Rouzic E, Benichou S
Retrovirology. 2005
PubMed ID: 15725353
The role of Vpr in HIV-1 pathogenesis.
Andersen JL, Planelles V
Curr HIV Res. 2005
PubMed ID: 15638722
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice.
Liu Y, Nakagawa Y, Wang Y, Sakurai R, Tripathi PV, Lutfy K, Friedman TC
Diabetes. 2005
PubMed ID: 15616008
The human glucocorticoid receptor (hGR) beta isoform suppresses the transcriptional activity of hGRalpha by interfering with formation of active coactivator complexes.
Charmandari E, Chrousos GP, Ichijo T, Bhattacharyya N, Vottero A, Souvatzoglou E, Kino T
Mol Endocrinol. 2005
PubMed ID: 15459252
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
Evidence for glucocorticoid receptor transport on microtubules by dynein.
Harrell JM, Murphy PJ, Morishima Y, Chen H, Mansfield JF, Galigniana MD, Pratt WB
J Biol Chem. 2004
PubMed ID: 15485845
A rapid and simple method for detection of Asn363Ser polymorphism of the human glucocorticoid receptor gene.
Majnik J, Patócs A, Balogh K, Tóth M, Rácz K
J Steroid Biochem Mol Biol. 2004
PubMed ID: 15698551
Knockdown of glucocorticoid receptor expression by RNA interference promotes cell proliferation in murine macrophage RAW264.7 cells.
Zhu XY, Liu YJ, Lu J, Xu RB
J Steroid Biochem Mol Biol. 2004
PubMed ID: 15698542
Reduced glucocorticoid and estrogen receptor alpha messenger ribonucleic acid levels in the amygdala of patients with major mental illness.
Perlman WR, Webster MJ, Kleinman JE, Weickert CS
Biol Psychiatry. 2004
PubMed ID: 15576061
Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus.
Garcia A, Steiner B, Kronenberg G, Bick-Sander A, Kempermann G
Aging Cell. 2004
PubMed ID: 15569353
TATA box binding protein induces structure in the recombinant glucocorticoid receptor AF1 domain.
Kumar R, Volk DE, Li J, Lee JC, Gorenstein DG, Thompson EB
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15545613
Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.
Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq C, Yamamoto KR
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15501915
Inhibition of glucocorticoid receptor binding by nitric oxide in endotoxemic rats.
Duma D, Silva-Santos JE, Assreuy J
Crit Care Med. 2004
PubMed ID: 15640646
Characterization of a promoter polymorphism in the glucocorticoid receptor gene and its relationship to three other polymorphisms.
van Rossum EF, Roks PH, de Jong FH, Brinkmann AO, Pols HA, Koper JW, Lamberts SW
Clin Endocrinol (Oxf). 2004
PubMed ID: 15521959
Structure-functional analysis of human immunodeficiency virus type 1 (HIV-1) Vpr: role of leucine residues on Vpr-mediated transactivation and virus replication.
Thotala D, Schafer EA, Tungaturthi PK, Majumder B, Janket ML, Wagner M, Srinivasan A, Watkins S, Ayyavoo V
Virology. 2004
PubMed ID: 15380361
A pilot study exploring the role of glucocorticoid receptor variants in primary biliary cirrhosis and primary sclerosing cholangitis.
ter Borg PC, Hagendorf A, van Buuren HR, Koper JW, Lamberts SW
Neth J Med. 2004
PubMed ID: 15635817
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Identification of the pregnancy hormone relaxin as glucocorticoid receptor agonist.
Dschietzig T, Bartsch C, Stangl V, Baumann G, Stangl K
FASEB J. 2004
PubMed ID: 15289446
A single amino acid change in the first zinc finger of the DNA binding domain of the glucocorticoid receptor regulates differential promoter selectivity.
Necela BM, Cidlowski JA
J Biol Chem. 2004
PubMed ID: 15220338
The DNA sequence and comparative analysis of human chromosome 5.
Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM
Nature. 2004
PubMed ID: 15372022
Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death.
Purton JF, Monk JA, Liddicoat DR, Kyparissoudis K, Sakkal S, Richardson SJ, Godfrey DI, Cole TJ
J Immunol. 2004
PubMed ID: 15356129
TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death.
Zhan Y, Funda DP, Every AL, Fundova P, Purton JF, Liddicoat DR, Cole TJ, Godfrey DI, Brady JL, Mannering SI, Harrison LC, Lew AM
Int Immunol. 2004
PubMed ID: 15262900
Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability.
Wei Q, Lu XY, Liu L, Schafer G, Shieh KR, Burke S, Robinson TE, Watson SJ, Seasholtz AF, Akil H
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15280545
Dysfunctional interaction of C/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells.
Roth M, Johnson PR, Borger P, Bihl MP, Rüdiger JJ, King GG, Ge Q, Hostettler K, Burgess JK, Black JL, Tamm M
N Engl J Med. 2004
PubMed ID: 15295049
Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding d
Bodwell JE, Kingsley LA, Hamilton JW
Chem Res Toxicol. 2004
PubMed ID: 15310238
The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a beneficial body composition and muscle strength in young adults.
van Rossum EF, Voorhoeve PG, te Velde SJ, Koper JW, Delemarre-van de Waal HA, Kemper HC, Lamberts SW
J Clin Endocrinol Metab. 2004
PubMed ID: 15292341
Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men.
van Rossum EF, Feelders RA, van den Beld AW, Uitterlinden AG, Janssen JA, Ester W, Brinkmann AO, Grobbee DE, de Jong FH, Pols HA, Koper JW, Lamberts SW
Am J Med. 2004
PubMed ID: 15276593
Distinct LIM domains of Hic-5/ARA55 are required for nuclear matrix targeting and glucocorticoid receptor binding and coactivation.
Guerrero-Santoro J, Yang L, Stallcup MR, DeFranco DB
J Cell Biochem. 2004
PubMed ID: 15211577
Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4.
Sitz JH, Tigges M, Baumgärtel K, Khaspekov LG, Lutz B
Mol Cell Biol. 2004
PubMed ID: 15199138
The heat shock protein 70 cochaperone hip enhances functional maturation of glucocorticoid receptor.
Nelson GM, Prapapanich V, Carrigan PE, Roberts PJ, Riggs DL, Smith DF
Mol Endocrinol. 2004
PubMed ID: 15071092
Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel.
Hawkins GA, Amelung PJ, Smith RS, Jongepier H, Howard TD, Koppelman GH, Meyers DA, Bleecker ER, Postma DS
DNA Seq. 2004
PubMed ID: 15497438
Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome?
Kino T, Chrousos GP
Ann N Y Acad Sci. 2004
PubMed ID: 15265780
The origin and functions of multiple human glucocorticoid receptor isoforms.
Lu NZ, Cidlowski JA
Ann N Y Acad Sci. 2004
PubMed ID: 15265776
A mutation of the glucocorticoid receptor gene in patients with systemic lupus erythematosus.
Lee YM, Fujiwara J, Munakata Y, Ishii T, Sugawara A, Kaku M, Kokubun S, Sasaki T, Funato T
Tohoku J Exp Med. 2004
PubMed ID: 15212141
The manifold actions of the protein inhibitor of activated STAT proteins on the transcriptional activity of mineralocorticoid and glucocorticoid receptors in neural cells.
Tirard M, Jasbinsek J, Almeida OF, Michaelidis TM
J Mol Endocrinol. 2004
PubMed ID: 15171715
3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.
Wu B, Li P, Liu Y, Lou Z, Ding Y, Shu C, Ye S, Bartlam M, Shen B, Rao Z
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15159550
Region-specific onset of handling-induced changes in corticotropin-releasing factor and glucocorticoid receptor expression.
Fenoglio KA, Brunson KL, Avishai-Eliner S, Chen Y, Baram TZ
Endocrinology. 2004
PubMed ID: 15044366
Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus.
Opherk C, Tronche F, Kellendonk C, Kohlmüller D, Schulze A, Schmid W, Schütz G
Mol Endocrinol. 2004
PubMed ID: 15031319
Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors.
Wang Q, Blackford JA, Song LN, Huang Y, Cho S, Simons SS
Mol Endocrinol. 2004
PubMed ID: 15016838
The genetic association database.
Becker KG, Barnes KC, Bright TJ, Wang SA
Nat Genet. 2004
PubMed ID: 15118671
Altered epithelial cell proportions in the fetal lung of glucocorticoid receptor null mice.
Cole TJ, Solomon NM, Van Driel R, Monk JA, Bird D, Richardson SJ, Dilley RJ, Hooper SB
Am J Respir Cell Mol Biol. 2004
PubMed ID: 14578211
Differential expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development.
Thompson A, Han VK, Yang K
J Steroid Biochem Mol Biol. 2004
PubMed ID: 15145446
Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1.
Kino T, Pavlakis GN
DNA Cell Biol. 2004
PubMed ID: 15142377
Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development.
Speirs HJ, Seckl JR, Brown RW
J Endocrinol. 2004
PubMed ID: 15072571
Reconstitution of glucocorticoid receptor-dependent transcription in vivo.
Trotter KW, Archer TK
Mol Cell Biol. 2004
PubMed ID: 15060156
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome Res. 2004
PubMed ID: 15060019
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Steroid-responsive sequences in the human glucocorticoid receptor gene 1A promoter.
Geng CD, Vedeckis WV
Mol Endocrinol. 2004
PubMed ID: 15044598
Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes.
Stavreva DA, Müller WG, Hager GL, Smith CL, McNally JG
Mol Cell Biol. 2004
PubMed ID: 15024059
The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II interact with and mutually affect each other's transcriptional activities: implications for intermediary metabolism.
De Martino MU, Bhattachryya N, Alesci S, Ichijo T, Chrousos GP, Kino T
Mol Endocrinol. 2004
PubMed ID: 14739255
Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress.
Froger N, Palazzo E, Boni C, Hanoun N, Saurini F, Joubert C, Dutriez-Casteloot I, Enache M, Maccari S, Barden N, Cohen-Salmon C, Hamon M, Lanfumey L
J Neurosci. 2004
PubMed ID: 15028772
Molecular chaperones function as steroid receptor nuclear mobility factors.
Elbi C, Walker DA, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB
Proc Natl Acad Sci U S A. 2004
PubMed ID: 14978266
Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth.
Tronche F, Opherk C, Moriggl R, Kellendonk C, Reimann A, Schwake L, Reichardt HM, Stangl K, Gau D, Hoeflich A, Beug H, Schmid W, Schütz G
Genes Dev. 2004
PubMed ID: 15037546
Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells.
Wang L, Hsu CL, Ni J, Wang PH, Yeh S, Keng P, Chang C
Mol Cell Biol. 2004
PubMed ID: 14966297
Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development.
Kalinichenko VV, Gusarova GA, Kim IM, Shin B, Yoder HM, Clark J, Sapozhnikov AM, Whitsett JA, Costa RH
Am J Physiol Lung Cell Mol Physiol. 2004
PubMed ID: 14607778
Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation.
Ladd CO, Huot RL, Thrivikraman KV, Nemeroff CB, Plotsky PM
Biol Psychiatry. 2004
PubMed ID: 14960289
Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype.
Stevens A, Ray DW, Zeggini E, John S, Richards HL, Griffiths CE, Donn R
J Clin Endocrinol Metab. 2004
PubMed ID: 14764810
Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress.
Wüst S, Van Rossum EF, Federenko IS, Koper JW, Kumsta R, Hellhammer DH
J Clin Endocrinol Metab. 2004
PubMed ID: 14764763
Glucocorticoid Receptor Counteracts Tumorigenic Activity of Akt in Skin through Interference with the Phosphatidylinositol 3-Kinase Signaling Pathway.
Leis H, Page A, Ramírez A, Bravo A, Segrelles C, Paramio J, Barettino D, Jorcano JL, Pérez P
Mol Endocrinol. 2004
PubMed ID: 14615607
Regulation of nuclear retention of glucocorticoid receptor by nuclear Hsp90.
Tago K, Tsukahara F, Naruse M, Yoshioka T, Takano K
Mol Cell Endocrinol. 2004
PubMed ID: 15062560
Polymorphisms in genes involved in the corticosteroid response and the outcome of childhood acute lymphoblastic leukemia.
Fleury I, Primeau M, Doreau A, Costea I, Moghrabi A, Sinnett D, Krajinovic M
Am J Pharmacogenomics. 2004
PubMed ID: 15462611
The glucocorticoid receptor mediates the thymic epithelial cell-induced apoptosis of CD4+8+ thymic lymphoma cells.
Zilberman Y, Zafrir E, Ovadia H, Yefenof E, Guy R, Sionov RV
Cell Immunol. 2004
PubMed ID: 15051511
Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition.
van Rossum EF, Lamberts SW
Recent Prog Horm Res. 2004
PubMed ID: 14749509
Low prevalence of the N363S polymorphism of the glucocorticoid receptor in South Asians living in the United Kingdom.
Syed AA, Irving JA, Redfern CP, Hall AG, Unwin NC, White M, Bhopal RS, Alberti KG, Weaver JU
J Clin Endocrinol Metab. 2004
PubMed ID: 14715855
Interleukin 1alpha (IL-1alpha) induced activation of p38 mitogen-activated protein kinase inhibits glucocorticoid receptor function.
Wang X, Wu H, Miller AH
Mol Psychiatry. 2004
PubMed ID: 14699442
Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.
Zhang T, Haws P, Wu Q
Genome Res. 2004
PubMed ID: 14672974
Transcriptome analysis of mouse stem cells and early embryos.
Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS
PLoS Biol. 2003
PubMed ID: 14691545
Amygdala kindling increases fear responses and decreases glucocorticoid receptor mRNA expression in hippocampal regions.
Kalynchuk LE, Meaney MJ
Prog Neuropsychopharmacol Biol Psychiatry. 2003
PubMed ID: 14659477
Identification of a novel glucocorticoid receptor mutation in budesonide-resistant human bronchial epithelial cells.
Kunz S, Sandoval R, Carlsson P, Carlstedt-Duke J, Bloom JW, Miesfeld RL
Mol Endocrinol. 2003
PubMed ID: 12920235
Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor.
Rogatsky I, Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq CM, Darimont BD, Garabedian MJ, Yamamoto KR
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14617768
Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index.
van Rossum EF, Koper JW, van den Beld AW, Uitterlinden AG, Arp P, Ester W, Janssen JA, Brinkmann AO, de Jong FH, Grobbee DE, Pols HA, Lamberts SW
Clin Endocrinol (Oxf). 2003
PubMed ID: 14616881
Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta action.
Li G, Wang S, Gelehrter TD
J Biol Chem. 2003
PubMed ID: 12902338
STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene.
Lerner L, Henriksen MA, Zhang X, Darnell JE
Genes Dev. 2003
PubMed ID: 14522952
T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha.
Chen D, Lucey MJ, Phoenix F, Lopez-Garcia J, Hart SM, Losson R, Buluwela L, Coombes RC, Chambon P, Schär P, Ali S
J Biol Chem. 2003
PubMed ID: 12874288
T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation.
Brewer JA, Khor B, Vogt SK, Muglia LM, Fujiwara H, Haegele KE, Sleckman BP, Muglia LJ
Nat Med. 2003
PubMed ID: 12949501
Quantification and glucocorticoid regulation of glucocorticoid receptor transcripts in two human leukemic cell lines.
Pedersen KB, Vedeckis WV
Biochemistry. 2003
PubMed ID: 12974633
PLZF is a negative regulator of retinoic acid receptor transcriptional activity.
Martin PJ, Delmotte MH, Formstecher P, Lefebvre P
Nucl Recept. 2003
PubMed ID: 14521715
[Analysis on association of glucocorticoid receptor gene polymorphism with steroid-resistance in idiopathic nephrotic syndrome of children]
Ye JW, Ding J, Huang JP, Chen Y, Yao Y, Xiao HJ, Yang JY, Shen Y, Meng Q
Zhonghua Er Ke Za Zhi. 2003
PubMed ID: 14733805
Yellow fluorescent protein-tagged and cyan fluorescent protein-tagged imaging analysis of glucocorticoid receptor and importins in single living cells.
Tanaka M, Nishi M, Morimoto M, Sugimoto T, Kawata M
Endocrinology. 2003
PubMed ID: 12933681
BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.
Hsiao PW, Fryer CJ, Trotter KW, Wang W, Archer TK
Mol Cell Biol. 2003
PubMed ID: 12917342
Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression.
Kodama T, Shimizu N, Yoshikawa N, Makino Y, Ouchida R, Okamoto K, Hisada T, Nakamura H, Morimoto C, Tanaka H
J Biol Chem. 2003
PubMed ID: 12810720
[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese]
Chi LQ, Zhang C, Luo B, Sun HY
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003
PubMed ID: 12903052
The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus.
Roussel R, Reis AF, Dubois-Laforgue D, Bellanné-Chantelot C, Timsit J, Velho G
Clin Endocrinol (Oxf). 2003
PubMed ID: 12864802
Disruption of glucocorticoid receptor exon 2 yields a ligand-responsive C-terminal fragment that regulates gene expression.
Mittelstadt PR, Ashwell JD
Mol Endocrinol. 2003
PubMed ID: 12750452
Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital.
Yoshinari K, Kobayashi K, Moore R, Kawamoto T, Negishi M
FEBS Lett. 2003
PubMed ID: 12885400
Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils.
Xu Q, Leung DY, Kisich KO
J Biol Chem. 2003
PubMed ID: 12738786
Protein 14-3-3sigma interacts with and favors cytoplasmic subcellular localization of the glucocorticoid receptor, acting as a negative regulator of the glucocorticoid signaling pathway.
Kino T, Souvatzoglou E, De Martino MU, Tsopanomihalu M, Wan Y, Chrousos GP
J Biol Chem. 2003
PubMed ID: 12730237
Long-term adiposity changes are related to a glucocorticoid receptor polymorphism in young females.
Tremblay A, Bouchard L, Bouchard C, Després JP, Drapeau V, Pérusse L
J Clin Endocrinol Metab. 2003
PubMed ID: 12843156
The relation between two polymorphisms in the glucocorticoid receptor gene and body mass index, blood pressure and cholesterol in obese patients.
Di Blasio AM, van Rossum EF, Maestrini S, Berselli ME, Tagliaferri M, Podestà F, Koper JW, Liuzzi A, Lamberts SW
Clin Endocrinol (Oxf). 2003
PubMed ID: 12807506
Cytosolic glucocorticoid receptor interaction with nuclear factor-kappa B proteins in rat liver cells.
Widén C, Gustafsson JA, Wikström AC
Biochem J. 2003
PubMed ID: 12672265
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism.
Kauppi B, Jakob C, Färnegårdh M, Yang J, Ahola H, Alarcon M, Calles K, Engström O, Harlan J, Muchmore S, Ramqvist AK, Thorell S, Ohman L, Greer J, Gustafsson JA, Carlstedt-Duke J, Carlquist M
J Biol Chem. 2003
PubMed ID: 12686538
Association of obesity, but not diabetes or hypertension, with glucocorticoid receptor N363S variant.
Lin RC, Wang XL, Dalziel B, Caterson ID, Morris BJ
Obes Res. 2003
PubMed ID: 12805402
The glucocorticoid receptor as a potential target to reduce cocaine abuse.
Deroche-Gamonet V, Sillaber I, Aouizerate B, Izawa R, Jaber M, Ghozland S, Kellendonk C, Le Moal M, Spanagel R, Schütz G, Tronche F, Piazza PV
J Neurosci. 2003
PubMed ID: 12805318
Dissecting adrenal and behavioral responses to stress by targeted gene inactivation in mice.
Brewer JA, Bethin KE, Schaefer ML, Muglia LM, Vogt SK, Weninger SC, Majzoub JA, Muglia LJ
Stress. 2003
PubMed ID: 12775331
Molecular origins for the dominant negative function of human glucocorticoid receptor beta.
Yudt MR, Jewell CM, Bienstock RJ, Cidlowski JA
Mol Cell Biol. 2003
PubMed ID: 12773573
Regulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140.
Tazawa H, Osman W, Shoji Y, Treuter E, Gustafsson JA, Zilliacus J
Mol Cell Biol. 2003
PubMed ID: 12773562
Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms.
Bray PJ, Cotton RG
Hum Mutat. 2003
PubMed ID: 12754700
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification.
Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW
Mol Cell Biol. 2003
PubMed ID: 12748280
Chronic glucocorticoid receptor activation impairs CREB transcriptional activity in clonal neurons.
Föcking M, Hölker I, Trapp T
Biochem Biophys Res Commun. 2003
PubMed ID: 12727214
Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-xL.
Gascoyne DM, Kypta RM, Vivanco MM
J Biol Chem. 2003
PubMed ID: 12637494
Anthrax lethal factor represses glucocorticoid and progesterone receptor activity.
Webster JI, Tonelli LH, Moayeri M, Simons SS, Leppla SH, Sternberg EM
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12724519
Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor co-activator by sequestering Daxx to the PML oncogenic domains (PODs) to enhance its transactivation potential.
Lin DY, Lai MZ, Ann DK, Shih HM
J Biol Chem. 2003
PubMed ID: 12595526
Alteration of cadherin in dexamethasone-induced cataract organ-cultured rat lens.
Lyu J, Kim JA, Chung SK, Kim KS, Joo CK
Invest Ophthalmol Vis Sci. 2003
PubMed ID: 12714641
Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735.
Stevens A, Garside H, Berry A, Waters C, White A, Ray D
Mol Endocrinol. 2003
PubMed ID: 12569182
Glucocorticoid receptor interactions with glucocorticoids: evaluation by molecular modeling and functional analysis of glucocorticoid receptor mutants.
Hammer S, Spika I, Sippl W, Jessen G, Kleuser B, Höltje HD, Schäfer-Korting M
Steroids. 2003
PubMed ID: 12787894
Human immunodeficiency virus type 1 (HIV-1) Vpr enhances expression from unintegrated HIV-1 DNA.
Poon B, Chen IS
J Virol. 2003
PubMed ID: 12634356
Loss of p16INK4a results in increased glucocorticoid receptor activity during fibrosarcoma development.
Roca R, Kypta RM, Vivanco MM
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12624188
Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1.
Subramaniam N, Campión J, Rafter I, Okret S
Biochem J. 2003
PubMed ID: 12487626
Association of coronary artery disease with glucocorticoid receptor N363S variant.
Lin RC, Wang XL, Morris BJ
Hypertension. 2003
PubMed ID: 12623935
Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity.
Schaaf MJ, Cidlowski JA
Mol Cell Biol. 2003
PubMed ID: 12612067
Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97).
Rajendran RR, Nye AC, Frasor J, Balsara RD, Martini PG, Katzenellenbogen BS
J Biol Chem. 2003
PubMed ID: 12466272
Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2.
Leung KC, Doyle N, Ballesteros M, Sjogren K, Watts CK, Low TH, Leong GM, Ross RJ, Ho KK
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12552091
Overexpressed glucocorticoid receptor negatively regulates gene expression under conditions that favour accumulation of non-hormone-binding forms of the receptor.
Siriani D, Mitsiou DJ, Alexis MN
J Steroid Biochem Mol Biol. 2003
PubMed ID: 12711001
Disruption of eyelid and cornea development by targeted overexpression of the glucocorticoid receptor.
Cascallana JL, Bravo A, Page A, Budunova I, Slaga TJ, Jorcano JL, Pérez P
Int J Dev Biol. 2003
PubMed ID: 12653252
STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation.
Floyd ZE, Stephens JM
Diabetes. 2003
PubMed ID: 12540601
A second pathway for modulating glucocorticoid receptor transactivation properties.
Chen S, Simons SS
Mol Cell Endocrinol. 2003
PubMed ID: 12581885
Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples.
Yoshimura K, Hanaoka T, Ohnami S, Ohnami S, Kohno T, Liu Y, Yoshida T, Sakamoto H, Tsugane S
J Hum Genet. 2003
PubMed ID: 14634838
Localization of the glucocorticoid receptor mRNA in cartilage and bone cells of the rat. An in situ hybridization study.
Silvestrini G, Mocetti P, Di Grezia R, Berni S, Bonucci E
Eur J Histochem. 2003
PubMed ID: 14514416
HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific.
Hogan TH, Nonnemacher MR, Krebs FC, Henderson A, Wigdahl B
Biomed Pharmacother. 2003
PubMed ID: 12642036
Characterization of glucocorticoid receptor translocation, cytoplasmic IkappaB, nuclear NFkappaB, and activation of NFkappaB in T lymphocytes exposed to stress-inducible concentrations of corticosterone in vivo.
Pruett SB, Fan R, Zheng Q
Int Immunopharmacol. 2003
PubMed ID: 12538030
The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development.
Kaplan F, Comber J, Sladek R, Hudson TJ, Muglia LJ, Macrae T, Gagnon S, Asada M, Brewer JA, Sweezey NB
Am J Respir Cell Mol Biol. 2003
PubMed ID: 12495930
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein.
Jiang H, Nucifora FC, Ross CA, DeFranco DB
Hum Mol Genet. 2003
PubMed ID: 12490527
Development of the fetal intestine in mice lacking the glucocorticoid receptor (GR).
Gartner H, Graul MC, Oesterreicher TJ, Finegold MJ, Henning SJ
J Cell Physiol. 2003
PubMed ID: 12447992
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
RanBPM, a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor.
Rao MA, Cheng H, Quayle AN, Nishitani H, Nelson CC, Rennie PS
J Biol Chem. 2002
PubMed ID: 12361945
Carboxyl terminus of hVIP/mov34 is critical for HIV-1-Vpr interaction and glucocorticoid-mediated signaling.
Ramanathan MP, Curley E, Su M, Chambers JA, Weiner DB
J Biol Chem. 2002
PubMed ID: 12237292
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T
J Immunol. 2002
PubMed ID: 12444143
Spatial and temporal patterns of expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy.
Thompson A, Han VK, Yang K
Biol Reprod. 2002
PubMed ID: 12444044
Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice.
Purton JF, Zhan Y, Liddicoat DR, Hardy CL, Lew AM, Cole TJ, Godfrey DI
Eur J Immunol. 2002
PubMed ID: 12442337
Antagonism of glucocorticoid receptor transactivity and cell growth inhibition by transforming growth factor-beta through AP-1-mediated transcriptional repression.
Periyasamy S, Sánchez ER
Int J Biochem Cell Biol. 2002
PubMed ID: 12379279
Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade.
Wong CW, McNally C, Nickbarg E, Komm BS, Cheskis BJ
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12415108
Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor.
Tian S, Poukka H, Palvimo JJ, Jänne OA
Biochem J. 2002
PubMed ID: 12144530
Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr.
Kino T, Tsukamoto M, Chrousos G
Biochem Biophys Res Commun. 2002
PubMed ID: 12379213
Molecular modelling of the human glucocorticoid receptor (hGR) ligand-binding domain (LBD) by homology with the human estrogen receptor alpha (hERalpha) LBD: quantitative structure-activity relationships within a series of CYP3A4 inducers where induction
Lewis DF, Ogg MS, Goldfarb PS, Gibson GG
J Steroid Biochem Mol Biol. 2002
PubMed ID: 12477485
Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation.
Itoh M, Adachi M, Yasui H, Takekawa M, Tanaka H, Imai K
Mol Endocrinol. 2002
PubMed ID: 12351702
A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels.
van Rossum EF, Koper JW, Huizenga NA, Uitterlinden AG, Janssen JA, Brinkmann AO, Grobbee DE, de Jong FH, van Duyn CM, Pols HA, Lamberts SW
Diabetes. 2002
PubMed ID: 12351458
Expression of glucocorticoid receptor alpha- and beta-isoforms in human cells and tissues.
Pujols L, Mullol J, Roca-Ferrer J, Torrego A, Xaubet A, Cidlowski JA, Picado C
Am J Physiol Cell Physiol. 2002
PubMed ID: 12225995
Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.
Kino T, Gragerov A, Slobodskaya O, Tsopanomichalou M, Chrousos GP, Pavlakis GN
J Virol. 2002
PubMed ID: 12208951
Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain.
Kaul S, Murphy PJ, Chen J, Brown L, Pratt WB, Simons SS
J Biol Chem. 2002
PubMed ID: 12145311
Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly.
Kanelakis KC, Shewach DS, Pratt WB
J Biol Chem. 2002
PubMed ID: 12093808
[Response to glucocorticoid treatment in asthma. The role of alpha and beta isoforms of the glucocorticoid receptor]
Torrego A, Pujols L, Picado C
Arch Bronconeumol. 2002
PubMed ID: 12237016
The mineralocorticoid receptor may compensate for the loss of the glucocorticoid receptor at specific stages of mammary gland development.
Kingsley-Kallesen M, Mukhopadhyay SS, Wyszomierski SL, Schanler S, Schütz G, Rosen JM
Mol Endocrinol. 2002
PubMed ID: 12198239
Potentiation of glucocorticoid receptor transcriptional activity by sumoylation.
Le Drean Y, Mincheneau N, Le Goff P, Michel D
Endocrinology. 2002
PubMed ID: 12193561
Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a c
Zhao Y, Goto K, Saitoh M, Yanase T, Nomura M, Okabe T, Takayanagi R, Nawata H
J Biol Chem. 2002
PubMed ID: 12039962
Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo.
Brewer JA, Kanagawa O, Sleckman BP, Muglia LJ
J Immunol. 2002
PubMed ID: 12165507
Glucocorticoid receptor domain requirements for chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter in different nucleoprotein contexts.
Keeton EK, Fletcher TM, Baumann CT, Hager GL, Smith CL
J Biol Chem. 2002
PubMed ID: 12029095
Mutations flanking the polyglutamine repeat in the modulatory domain of rat glucocorticoid receptor lead to an increase in affinity for hormone.
Heeley RP, Rusconi SG, Sutcliffe RG, Kenyon CJ
Endocr Res. 2002
PubMed ID: 12489571
Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase-9 expression in rat mesangial cells: involvement of nuclear factor-kappaB and Ets transcription factors.
Eberhardt W, Schulze M, Engels C, Klasmeier E, Pfeilschifter J
Mol Endocrinol. 2002
PubMed ID: 12145332
The glucocorticoid receptor: coding a diversity of proteins and responses through a single gene.
Yudt MR, Cidlowski JA
Mol Endocrinol. 2002
PubMed ID: 12145329
Green fluorescent protein-glucocorticoid receptor knockin mice reveal dynamic receptor modulation during thymocyte development.
Brewer JA, Sleckman BP, Swat W, Muglia LJ
J Immunol. 2002
PubMed ID: 12133953
A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1.
Kucera T, Waltner-Law M, Scott DK, Prasad R, Granner DK
J Biol Chem. 2002
PubMed ID: 12118039
Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor.
Hulkko SM, Zilliacus J
Biochem Biophys Res Commun. 2002
PubMed ID: 12099703
RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding.
Schulz M, Eggert M, Baniahmad A, Dostert A, Heinzel T, Renkawitz R
J Biol Chem. 2002
PubMed ID: 12011091
Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo.
Wang Z, Frederick J, Garabedian MJ
J Biol Chem. 2002
PubMed ID: 12000743
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition.
Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, McKee DD, Consler TG, Parks DJ, Stewart EL, Willson TM, Lambert MH, Moore JT, Pearce KH, Xu HE
Cell. 2002
PubMed ID: 12151000
Substitution of arginine for cysteine 643 of the glucocorticoid receptor reduces its steroid-binding affinity and transcriptional activity.
Nagano M, Nakamura T, Niimi S, Fujino T, Nishimura T, Murayama N, Ishida S, Ozawa S, Saito Y, Sawada J
Cancer Lett. 2002
PubMed ID: 12430185
Involvement of the glucocorticoid receptor in the pathogenesis of rheumatoid arthritis.
Neeck G, Kluter A, Dotzlaw H, Eggert M
Ann N Y Acad Sci. 2002
PubMed ID: 12114309
Mechanisms of corticosteroid resistance in rheumatoid arthritis: a putative role for the corticosteroid receptor beta isoform.
Chikanza IC
Ann N Y Acad Sci. 2002
PubMed ID: 12114257
[Changes of GR and HSP70 and their relationships with secondary hepatic damage after severe trauma]
Luo D, Zhou J, Liu B, Huang X, Liu D
Zhonghua Gan Zang Bing Za Zhi. 2002
PubMed ID: 12113691
A novel, C-terminal dominant negative mutation of the GR causes familial glucocorticoid resistance through abnormal interactions with p160 steroid receptor coactivators.
Vottero A, Kino T, Combe H, Lecomte P, Chrousos GP
J Clin Endocrinol Metab. 2002
PubMed ID: 12050230
Inactivation of the GR in the nervous system affects energy accumulation.
Kellendonk C, Eiden S, Kretz O, Schütz G, Schmidt I, Tronche F, Simon E
Endocrinology. 2002
PubMed ID: 12021198
AUUUA motifs in the 3'UTR of human glucocorticoid receptor alpha and beta mRNA destabilize mRNA and decrease receptor protein expression.
Schaaf MJ, Cidlowski JA
Steroids. 2002
PubMed ID: 11996936
ATP-dependent mobilization of the glucocorticoid receptor during chromatin remodeling.
Fletcher TM, Xiao N, Mautino G, Baumann CT, Wolford R, Warren BS, Hager GL
Mol Cell Biol. 2002
PubMed ID: 11971959
Androgen receptor interactions with Oct-1 and Brn-1 are physically and functionally distinct.
González MI, Tovaglieri A, Robins DM
Mol Cell Endocrinol. 2002
PubMed ID: 11997177
Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors.
Kaul S, Blackford JA, Cho S, Simons SS
J Biol Chem. 2002
PubMed ID: 11812797
Glucocorticoid receptor binding in twin pairs is affected by shared environment but not by shared genes.
Blackhurst G, McElroy KP, Kenyon CJ, Fraser R, Swan L, Anderson N, Hillis S, Connell JM
J Steroid Biochem Mol Biol. 2002
PubMed ID: 11983486
Female pseudohermaphroditism caused by a novel homozygous missense mutation of the GR gene.
Mendonca BB, Leite MV, de Castro M, Kino T, Elias LL, Bachega TA, Arnhold IJ, Chrousos GP, Latronico AC
J Clin Endocrinol Metab. 2002
PubMed ID: 11932321
Characterization of promoter 1B in the human glucocorticoid receptor gene.
Nunez BS, Vedeckis WV
Mol Cell Endocrinol. 2002
PubMed ID: 12039077
Hyperthermic stress stimulates the association of both constitutive and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor.
Cvoro A, Matić G
Int J Biochem Cell Biol. 2002
PubMed ID: 11849995
A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins.
Davies TH, Ning YM, Sánchez ER
J Biol Chem. 2002
PubMed ID: 11751894
Interaction of C/EBPalpha and the glucocorticoid receptor in vivo and in nontransformed human cells.
Rüdiger JJ, Roth M, Bihl MP, Cornelius BC, Johnson M, Ziesche R, Block LH
FASEB J. 2002
PubMed ID: 11818365
Relationship between glucocorticoid-mediated early decrease of protein synthesis and the steady state decreases of glucocorticoid receptor and TGF-beta activator protein.
Cutroneo KR
Int J Biochem Cell Biol. 2002
PubMed ID: 11809422
Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex.
Kino T, Slobodskaya O, Pavlakis GN, Chrousos GP
J Biol Chem. 2002
PubMed ID: 11704662
Supervillin associates with androgen receptor and modulates its transcriptional activity.
Ting HJ, Yeh S, Nishimura K, Chang C
Proc Natl Acad Sci U S A. 2002
PubMed ID: 11792840
Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family.
Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S
Cytogenet Genome Res. 2002
PubMed ID: 12438750
Vanadate increases glucocorticoid receptor-mediated gene expression: a novel mechanism for potentiation of a steroid receptor.
Li Calzi S, Periyasamy S, Li DP, Sánchez ER
J Steroid Biochem Mol Biol. 2002
PubMed ID: 11867262
Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors.
Ko L, Cardona GR, Henrion-Caude A, Chin WW
Mol Cell Biol. 2002
PubMed ID: 11739747
A polymorphism in the promoter region of the glucocorticoid receptor gene is associated with its transcriptional activity.
Ikeda Y, Suehiro T, Tsuzura S, Shiinoki T, Kaneda T, Kumon Y, Hashimoto K
Endocr J. 2001
PubMed ID: 11873873
Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids.
Wallace AD, Cidlowski JA
J Biol Chem. 2001
PubMed ID: 11555652
Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms.
Poch E, González D, Giner V, Bragulat E, Coca A, de La Sierra A
Hypertension. 2001
PubMed ID: 11711524
Cortisone counteracts apoptosis-inducing effect of cortisol in human peripheral-blood mononuclear cells.
Hirano T, Horigome A, Takatani M, Oka K
Int Immunopharmacol. 2001
PubMed ID: 11710540
A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis.
Derijk RH, Schaaf MJ, Turner G, Datson NA, Vreugdenhil E, Cidlowski J, de Kloet ER, Emery P, Sternberg EM, Detera-Wadleigh SD
J Rheumatol. 2001
PubMed ID: 11708406
Pathologic human GR mutant has a transdominant negative effect on the wild-type GR by inhibiting its translocation into the nucleus: importance of the ligand-binding domain for intracellular GR trafficking.
Kino T, Stauber RH, Resau JH, Pavlakis GN, Chrousos GP
J Clin Endocrinol Metab. 2001
PubMed ID: 11701741
HIV-1 Vpr transactivates LTR-directed expression through sequences present within -278 to -176 and increases virus replication in vitro.
Vanitharani R, Mahalingam S, Rafaeli Y, Singh SP, Srinivasan A, Weiner DB, Ayyavoo V
Virology. 2001
PubMed ID: 11689055
Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory.
Oitzl MS, Reichardt HM, Joëls M, de Kloet ER
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11606764
The Asn363Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men.
Echwald SM, Sørensen TI, Andersen T, Pedersen O
Int J Obes Relat Metab Disord. 2001
PubMed ID: 11673782
Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2.
Sengupta S, Wasylyk B
Genes Dev. 2001
PubMed ID: 11562347
Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance.
Ruiz M, Lind U, Gåfvels M, Eggertsen G, Carlstedt-Duke J, Nilsson L, Holtmann M, Stierna P, Wikström AC, Werner S
Clin Endocrinol (Oxf). 2001
PubMed ID: 11589680
Interactions among the glucocorticoid receptor, lipoprotein lipase and adrenergic receptor genes and abdominal fat in the Québec Family Study.
Ukkola O, Pérusse L, Chagnon YC, Després JP, Bouchard C
Int J Obes Relat Metab Disord. 2001
PubMed ID: 11571596
Large-scale identification of mammalian proteins localized to nuclear sub-compartments.
Sutherland HG, Mumford GK, Newton K, Ford LV, Farrall R, Dellaire G, Cáceres JF, Bickmore WA
Hum Mol Genet. 2001
PubMed ID: 11555636
Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids.
Breslin MB, Geng CD, Vedeckis WV
Mol Endocrinol. 2001
PubMed ID: 11463861
Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription.
Chan SW, Hong W
J Biol Chem. 2001
PubMed ID: 11358960
Quantitative trait loci for body weight in the intercross between SM/J and A/J mice.
Anunciado RV, Nishimura M, Mori M, Ishikawa A, Tanaka S, Horio F, Ohno T, Namikawa T
Exp Anim. 2001
PubMed ID: 11515095
Molecular identification and characterization of a and b forms of the glucocorticoid receptor.
Yudt MR, Cidlowski JA
Mol Endocrinol. 2001
PubMed ID: 11435610
Physical interaction and functional synergy between glucocorticoid receptor and Ets2 proteins for transcription activation of the rat cytochrome P-450c27 promoter.
Mullick J, Anandatheerthavarada HK, Amuthan G, Bhagwat SV, Biswas G, Camasamudram V, Bhat NK, Reddy SE, Rao V, Avadhani NG
J Biol Chem. 2001
PubMed ID: 11279115
Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells.
de Lange P, Segeren CM, Koper JW, Wiemer E, Sonneveld P, Brinkmann AO, White A, Brogan IJ, de Jong FH, Lamberts SW
Cancer Res. 2001
PubMed ID: 11358809
Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus.
Galigniana MD, Radanyi C, Renoir JM, Housley PR, Pratt WB
J Biol Chem. 2001
PubMed ID: 11278753
The N363S polymorphism of the glucocorticoid receptor: potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus.
Dobson MG, Redfern CP, Unwin N, Weaver JU
J Clin Endocrinol Metab. 2001
PubMed ID: 11344238
Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary adrenal axis in the newborn rat.
Lesage J, Blondeau B, Grino M, Bréant B, Dupouy JP
Endocrinology. 2001
PubMed ID: 11316731
The cardiac K+ channel KCNQ1 is essential for gastric acid secretion.
Grahammer F, Herling AW, Lang HJ, Schmitt-Gräff A, Wittekindt OH, Nitschke R, Bleich M, Barhanin J, Warth R
Gastroenterology. 2001
PubMed ID: 11313306
Heterodimerization of mineralocorticoid and glucocorticoid receptors at a novel negative response element of the 5-HT1A receptor gene.
Ou XM, Storring JM, Kushwaha N, Albert PR
J Biol Chem. 2001
PubMed ID: 11278286
Candidate gene analysis in premature pubarche and adolescent hyperandrogenism.
Witchel SF, Smith R, Tomboc M, Aston CE
Fertil Steril. 2001
PubMed ID: 11287026
Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.
Zilliacus J, Holter E, Wakui H, Tazawa H, Treuter E, Gustafsson JA
Mol Endocrinol. 2001
PubMed ID: 11266503
Tsp509I polymorphism in exon 2 of the glucocorticoid receptor gene in relation to obesity and cortisol secretion: cohort study.
Rosmond R, Bouchard C, Björntorp P
BMJ. 2001
PubMed ID: 11250851
High constitutive glucocorticoid receptor beta in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids.
Strickland I, Kisich K, Hauk PJ, Vottero A, Chrousos GP, Klemm DJ, Leung DY
J Exp Med. 2001
PubMed ID: 11238589
Oct-1 preferentially interacts with androgen receptor in a DNA-dependent manner that facilitates recruitment of SRC-1.
Gonzalez MI, Robins DM
J Biol Chem. 2001
PubMed ID: 11096094
GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant.
Cole TJ, Myles K, Purton JF, Brereton PS, Solomon NM, Godfrey DI, Funder JW
Mol Cell Endocrinol. 2001
PubMed ID: 11223190
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Interactions among the glucocorticoid receptor, lipoprotein lipase, and adrenergic receptor genes and plasma insulin and lipid levels in the Quebec Family Study.
Ukkola O, Pérusse L, Weisnagel SJ, Bergeron J, Després JP, Rao DC, Bouchard C
Metabolism. 2001
PubMed ID: 11229437
Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer-binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor.
Wyszomierski SL, Rosen JM
Mol Endocrinol. 2001
PubMed ID: 11158330
Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces.
Savory JG, Préfontaine GG, Lamprecht C, Liao M, Walther RF, Lefebvre YA, Haché RJ
Mol Cell Biol. 2001
PubMed ID: 11154266
Identification of nucleolin as a glucocorticoid receptor interacting protein.
Schulz M, Schneider S, Lottspeich F, Renkawitz R, Eggert M
Biochem Biophys Res Commun. 2001
PubMed ID: 11162542
Central 5-hydroxytryptamine-2A receptor expression in transgenic mice bearing a glucocorticoid receptor antisense.
Cyr M, Charbonneau C, Morissette M, Rochford J, Barden N, Di Paolo T
Neuroendocrinology. 2001
PubMed ID: 11174015
Expression of the human glucocorticoid receptor alpha and beta isoforms in human respiratory epithelial cells and their regulation by dexamethasone.
Pujols L, Mullol J, Pérez M, Roca-Ferrer J, Juan M, Xaubet A, Cidlowski JA, Picado C
Am J Respir Cell Mol Biol. 2001
PubMed ID: 11152650
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins.
Connell P, Ballinger CA, Jiang J, Wu Y, Thompson LJ, Höhfeld J, Patterson C
Nat Cell Biol. 2001
PubMed ID: 11146632
Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways.
Widén C, Zilliacus J, Gustafsson JA, Wikström AC
J Biol Chem. 2000
PubMed ID: 11005817
A variant of the glucocorticoid receptor gene is not associated with adrenal androgen excess in women with polycystic ovary syndrome.
Kahsar-Miller M, Azziz R, Feingold E, Witchel SF
Fertil Steril. 2000
PubMed ID: 11119758
ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.
Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne OA
Mol Endocrinol. 2000
PubMed ID: 11117529
Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor.
Schneikert J, Hübner S, Langer G, Petri T, Jäättelä M, Reed J, Cato AC
EMBO J. 2000
PubMed ID: 11101523
Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock.
Reichardt HM, Umland T, Bauer A, Kretz O, Schütz G
Mol Cell Biol. 2000
PubMed ID: 11073999
Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells.
Sengupta S, Vonesch JL, Waltzinger C, Zheng H, Wasylyk B
EMBO J. 2000
PubMed ID: 11080152
Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice.
Gass P, Kretz O, Wolfer DP, Berger S, Tronche F, Reichardt HM, Kellendonk C, Lipp HP, Schmid W, Schütz G
EMBO Rep. 2000
PubMed ID: 11258486
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor.
Doucas V, Shi Y, Miyamoto S, West A, Verma I, Evans RM
Proc Natl Acad Sci U S A. 2000
PubMed ID: 11027313
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers.
Karst H, Karten YJ, Reichardt HM, de Kloet ER, Schütz G, Joëls M
Nat Neurosci. 2000
PubMed ID: 11017168
The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain.
Nissen RM, Yamamoto KR
Genes Dev. 2000
PubMed ID: 10995388
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
Ito K, Barnes PJ, Adcock IM
Mol Cell Biol. 2000
PubMed ID: 10958685
Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest.
Sherman MP, de Noronha CM, Pearce D, Greene WC
J Virol. 2000
PubMed ID: 10933727
Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling.
Purton JF, Boyd RL, Cole TJ, Godfrey DI
Immunity. 2000
PubMed ID: 10981961
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
The pro-apoptotic protein death-associated protein 3 (DAP3) interacts with the glucocorticoid receptor and affects the receptor function.
Hulkko SM, Wakui H, Zilliacus J
Biochem J. 2000
PubMed ID: 10903152
Functional interaction of the immunosuppressant mizoribine with the 14-3-3 protein.
Takahashi S, Wakui H, Gustafsson JA, Zilliacus J, Itoh H
Biochem Biophys Res Commun. 2000
PubMed ID: 10903900
Steroidogenic enzyme gene expression in the human heart.
Kayes-Wandover KM, White PC
J Clin Endocrinol Metab. 2000
PubMed ID: 10902803
A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein.
Mahajan MA, Samuels HH
Mol Cell Biol. 2000
PubMed ID: 10866662
Five missense variants in the amino-terminal domain of the glucocorticoid receptor: no association with puerperal psychosis or schizophrenia.
Feng J, Zheng J, Bennett WP, Heston LL, Jones IR, Craddock N, Sommer SS
Am J Med Genet. 2000
PubMed ID: 10898924
Interaction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix.
Yang L, Guerrero J, Hong H, DeFranco DB, Stallcup MR
Mol Biol Cell. 2000
PubMed ID: 10848625
Localization of glucocorticoid hormone receptors in mitochondria of human cells.
Scheller K, Sekeris CE, Krohne G, Hock R, Hansen IA, Scheer U
Eur J Cell Biol. 2000
PubMed ID: 10887960
Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis.
Honda M, Orii F, Ayabe T, Imai S, Ashida T, Obara T, Kohgo Y
Gastroenterology. 2000
PubMed ID: 10784585
Central 5-HT(1) and 5-HT(2) binding sites in transgenic mice with reduced glucocorticoid receptor number.
Farisse J, Héry F, Barden N, Héry M, Boulenguez P
Brain Res. 2000
PubMed ID: 10799679
5'-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events.
McCormick JA, Lyons V, Jacobson MD, Noble J, Diorio J, Nyirenda M, Weaver S, Ester W, Yau JL, Meaney MJ, Seckl JR, Chapman KE
Mol Endocrinol. 2000
PubMed ID: 10770488
Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate.
Almeida OF, Condé GL, Crochemore C, Demeneix BA, Fischer D, Hassan AH, Meyer M, Holsboer F, Michaelidis TM
FASEB J. 2000
PubMed ID: 10744634
The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function.
Zhu XG, Park KS, Kaneshige M, Bhat MK, Zhu Q, Mariash CN, McPhie P, Cheng SY
Mol Cell Biol. 2000
PubMed ID: 10713182
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen.
Knutti D, Kaul A, Kralli A
Mol Cell Biol. 2000
PubMed ID: 10713165
Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau1 activation domain.
Wallberg AE, Neely KE, Hassan AH, Gustafsson JA, Workman JL, Wright AP
Mol Cell Biol. 2000
PubMed ID: 10688647
The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver.
Schuetz EG, Schmid W, Schutz G, Brimer C, Yasuda K, Kamataki T, Bornheim L, Myles K, Cole TJ
Drug Metab Dispos. 2000
PubMed ID: 10681370
The glucocorticoid receptor: rapid exchange with regulatory sites in living cells.
McNally JG, Müller WG, Walker D, Wolford R, Hager GL
Science. 2000
PubMed ID: 10678832
The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies.
Freeman BC, Felts SJ, Toft DO, Yamamoto KR
Genes Dev. 2000
PubMed ID: 10691735
Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor.
Diamond MI, Robinson MR, Yamamoto KR
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10639135
Purification and primary structure of a macromolecular-translocation inhibitor II of glucocorticoid-receptor binding to nuclei from rat liver. Inhibitor II is the 11.5-kDa Zn2+-binding protein (parathymosin).
Okamoto K, Isohashi F
Eur J Biochem. 2000
PubMed ID: 10601862
The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin.
Tuckermann JP, Reichardt HM, Arribas R, Richter KH, Schütz G, Angel P
J Cell Biol. 1999
PubMed ID: 10613894
The nuclear-receptor interacting protein (RIP) 140 binds to the human glucocorticoid receptor and modulates hormone-dependent transactivation.
Windahl SH, Treuter E, Ford J, Zilliacus J, Gustafsson JA, McEwan IJ
J Steroid Biochem Mol Biol. 1999
PubMed ID: 10659697
A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.
Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW
J Biol Chem. 1999
PubMed ID: 10567404
The glucocorticoid receptor is required for stress erythropoiesis.
Bauer A, Tronche F, Wessely O, Kellendonk C, Reichardt HM, Steinlein P, Schütz G, Beug H
Genes Dev. 1999
PubMed ID: 10580006
Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing.
Rivers C, Levy A, Hancock J, Lightman S, Norman M
J Clin Endocrinol Metab. 1999
PubMed ID: 10566686
Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3.
Song CZ, Tian X, Gelehrter TD
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10518526
RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only weakly as a coactivator in cotransfection assays.
Gao T, Brantley K, Bolu E, McPhaul MJ
Mol Endocrinol. 1999
PubMed ID: 10517667
Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins.
Hittelman AB, Burakov D, Iñiguez-Lluhí JA, Freedman LP, Garabedian MJ
EMBO J. 1999
PubMed ID: 10508170
Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding.
Wang JM, Préfontaine GG, Lemieux ME, Pope L, Akimenko MA, Haché RJ
Mol Cell Biol. 1999
PubMed ID: 10490647
Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter.
Préfontaine GG, Walther R, Giffin W, Lemieux ME, Pope L, Haché RJ
J Biol Chem. 1999
PubMed ID: 10480874
A nuclear action of the eukaryotic cochaperone RAP46 in downregulation of glucocorticoid receptor activity.
Schneikert J, Hübner S, Martin E, Cato AC
J Cell Biol. 1999
PubMed ID: 10477749
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety.
Tronche F, Kellendonk C, Kretz O, Gass P, Anlag K, Orban PC, Bock R, Klein R, Schütz G
Nat Genet. 1999
PubMed ID: 10471508
The glucocorticoid receptor is essential for maintaining basal and dexamethasone-induced repression of the murine corticosteroid-binding globulin gene.
Cole TJ, Harris HJ, Hoong I, Solomon N, Smith R, Krozowski Z, Fullerton MJ
Mol Cell Endocrinol. 1999
PubMed ID: 10509797
Antiglucocorticoid activity of hepatocyte nuclear factor-6.
Pierreux CE, Stafford J, Demonte D, Scott DK, Vandenhaute J, O'Brien RM, Granner DK, Rousseau GG, Lemaigre FP
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10430878
Characterization of single-nucleotide polymorphisms in coding regions of human genes.
Cargill M, Altshuler D, Ireland J, Sklar P, Ardlie K, Patil N, Shaw N, Lane CR, Lim EP, Kalyanaraman N, Nemesh J, Ziaugra L, Friedland L, Rolfe A, Warrington J, Lipshutz R, Daley GQ, Lander ES
Nat Genet. 1999
PubMed ID: 10391209
Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.
Finotto S, Krieglstein K, Schober A, Deimling F, Lindner K, Brühl B, Beier K, Metz J, Garcia-Arraras JE, Roig-Lopez JL, Monaghan P, Schmid W, Cole TJ, Kellendonk C, Tronche F, Schütz G, Unsicker K
Development. 1999
PubMed ID: 10357937
Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids.
Subramaniam N, Treuter E, Okret S
J Biol Chem. 1999
PubMed ID: 10364267
The HIV-1 Vpr co-activator induces a conformational change in TFIIB.
Agostini I, Navarro JM, Bouhamdan M, Willetts K, Rey F, Spire B, Vigne R, Pomerantz R, Sire J
FEBS Lett. 1999
PubMed ID: 10359081
The structure of the nuclear hormone receptors.
Kumar R, Thompson EB
Steroids. 1999
PubMed ID: 10406480
Paracrine glucocorticoid activity produced by mouse thymic epithelial cells.
Pazirandeh A, Xue Y, Rafter I, Sjövall J, Jondal M, Okret S
FASEB J. 1999
PubMed ID: 10224232
Redox-dependent regulation of nuclear import of the glucocorticoid receptor.
Okamoto K, Tanaka H, Ogawa H, Makino Y, Eguchi H, Hayashi S, Yoshikawa N, Poellinger L, Umesono K, Makino I
J Biol Chem. 1999
PubMed ID: 10187825
Mutagenesis of the glucocorticoid receptor in mice.
Kellendonk C, Tronche F, Reichardt HM, Schütz G
J Steroid Biochem Mol Biol. 1999
PubMed ID: 10418999
Disrupted allocentric but preserved egocentric spatial learning in transgenic mice with impaired glucocorticoid receptor function.
Steckler T, Weis C, Sauvage M, Mederer A, Holsboer F
Behav Brain Res. 1999
PubMed ID: 10212055
Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor.
Kang HY, Yeh S, Fujimoto N, Chang C
J Biol Chem. 1999
PubMed ID: 10085091
Delimitation of two regions in the 90-kDa heat shock protein (Hsp90) able to interact with the glucocorticosteroid receptor (GR).
Jibard N, Meng X, Leclerc P, Rajkowski K, Fortin D, Schweizer-Groyer G, Catelli MG, Baulieu EE, Cadepond F
Exp Cell Res. 1999
PubMed ID: 10066374
The Cre/loxP system--a versatile tool to study glucocorticoid signalling in mice.
Reichardt HM, Kellendonk C, Tronche F, Schütz G
Biochem Soc Trans. 1999
PubMed ID: 10093711
Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function.
Makino Y, Yoshikawa N, Okamoto K, Hirota K, Yodoi J, Makino I, Tanaka H
J Biol Chem. 1999
PubMed ID: 9915858
Insulin inhibition of glucocorticoid-stimulated gene transcription: requirement for an insulin response element?
Pierreux CE, Rousseau GG, Lemaigre FP
Mol Cell Endocrinol. 1999
PubMed ID: 10195686
Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells.
Eickelberg O, Roth M, Lörx R, Bruce V, Rüdiger J, Johnson M, Block LH
J Biol Chem. 1999
PubMed ID: 9873044
The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor.
Kino T, Gragerov A, Kopp JB, Stauber RH, Pavlakis GN, Chrousos GP
J Exp Med. 1999
PubMed ID: 9874563
A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae.
Sato T, Jigami Y, Suzuki T, Uemura H
Mol Gen Genet. 1999
PubMed ID: 9928932
Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform.
Alen P, Claessens F, Schoenmakers E, Swinnen JV, Verhoeven G, Rombauts W, Peeters B
Mol Endocrinol. 1999
PubMed ID: 9892017
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.
Abbott BD, Schmid JE, Brown JG, Wood CR, White RD, Buckalew AR, Held GA
Toxicol Sci. 1999
PubMed ID: 10048155
Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).
Reyes JC, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M
EMBO J. 1998
PubMed ID: 9843504
AF-2-dependent potentiation of CCAAT enhancer binding protein beta-mediated transcriptional activation by glucocorticoid receptor.
Boruk M, Savory JG, Haché RJ
Mol Endocrinol. 1998
PubMed ID: 9817600
Genetic dissection of glucocorticoid receptor function in mice.
Tronche F, Kellendonk C, Reichardt HM, Schütz G
Curr Opin Genet Dev. 1998
PubMed ID: 9794823
Coactivator TIF1beta interacts with transcription factor C/EBPbeta and glucocorticoid receptor to induce alpha1-acid glycoprotein gene expression.
Chang CJ, Chen YL, Lee SC
Mol Cell Biol. 1998
PubMed ID: 9742105
Glucocorticoid receptor mRNA levels in bronchial epithelial cells of patients with COPD: influence of glucocorticoids.
Korn SH, Thunnissen FB, Wesseling GJ, Arends JW, Wouters EF
Respir Med. 1998
PubMed ID: 9926163
Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution.
Szpirer C, Szpirer J, Van Vooren P, Tissir F, Simon JS, Koike G, Jacob HJ, Lander ES, Helou K, Klinga-Levan K, Levan G
Mamm Genome. 1998
PubMed ID: 9716657
High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells.
Boonyaratanakornkit V, Melvin V, Prendergast P, Altmann M, Ronfani L, Bianchi ME, Taraseviciene L, Nordeen SK, Allegretto EA, Edwards DP
Mol Cell Biol. 1998
PubMed ID: 9671457
Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor tau 1-core activation domain and target factors.
Almlöf T, Wallberg AE, Gustafsson JA, Wright AP
Biochemistry. 1998
PubMed ID: 9649342
RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis.
Kullmann M, Schneikert J, Moll J, Heck S, Zeiner M, Gehring U, Cato AC
J Biol Chem. 1998
PubMed ID: 9603979
Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphorylation.
Rogatsky I, Waase CL, Garabedian MJ
J Biol Chem. 1998
PubMed ID: 9603939
[Expression of the nuclear glucocorticoid receptor in human pigment epithelium]
Schönfeld CL
Ophthalmologe. 1998
PubMed ID: 9703718
Recruitment of octamer transcription factors to DNA by glucocorticoid receptor.
Préfontaine GG, Lemieux ME, Giffin W, Schild-Poulter C, Pope L, LaCasse E, Walker P, Haché RJ
Mol Cell Biol. 1998
PubMed ID: 9584182
Glucocorticoid receptors are differentially expressed in the cells and tissues of the immune system.
Miller AH, Spencer RL, Pearce BD, Pisell TL, Azrieli Y, Tanapat P, Moday H, Rhee R, McEwen BS
Cell Immunol. 1998
PubMed ID: 9637764
DNA binding of the glucocorticoid receptor is not essential for survival.
Reichardt HM, Kaestner KH, Tuckermann J, Kretz O, Wessely O, Bock R, Gass P, Schmid W, Herrlich P, Angel P, Schütz G
Cell. 1998
PubMed ID: 9604929
Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.
Fryer CJ, Archer TK
Nature. 1998
PubMed ID: 9590696
Analysis of glucocorticoid signalling by gene targeting.
Reichardt HM, Kaestner KH, Wessely O, Gass P, Schmid W, Schütz G
J Steroid Biochem Mol Biol. 1998
PubMed ID: 9699863
Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells.
Cella N, Groner B, Hynes NE
Mol Cell Biol. 1998
PubMed ID: 9528750
A novel extracellular domain variant of the human integrin alpha 7 subunit generated by alternative intron splicing.
Leung E, Lim SP, Berg R, Yang Y, Ni J, Wang SX, Krissansen GW
Biochem Biophys Res Commun. 1998
PubMed ID: 9473524
Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities.
Ding XF, Anderson CM, Ma H, Hong H, Uht RM, Kushner PJ, Stallcup MR
Mol Endocrinol. 1998
PubMed ID: 9482670
A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo.
Huizenga NA, Koper JW, De Lange P, Pols HA, Stolk RP, Burger H, Grobbee DE, Brinkmann AO, De Jong FH, Lamberts SW
J Clin Endocrinol Metab. 1998
PubMed ID: 9435432
STAT3 acts as a co-activator of glucocorticoid receptor signaling.
Zhang Z, Jones S, Hagood JS, Fuentes NL, Fuller GM
J Biol Chem. 1997
PubMed ID: 9388192
The glucocorticoid receptor inhibits the human prolactin gene expression by interference with Pit-1 activity.
Nalda AM, Martial JA, Muller M
Mol Cell Endocrinol. 1997
PubMed ID: 9426156
The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U.
Eggert M, Michel J, Schneider S, Bornfleth H, Baniahmad A, Fackelmayer FO, Schmidt S, Renkawitz R
J Biol Chem. 1997
PubMed ID: 9353307
Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor.
Oakley RH, Webster JC, Sar M, Parker CR, Cidlowski JA
Endocrinology. 1997
PubMed ID: 9348235
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S
Gene. 1997
PubMed ID: 9373149
Absence of glucocorticoid receptor-beta in mice.
Otto C, Reichardt HM, Schütz G
J Biol Chem. 1997
PubMed ID: 9334249
Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor.
Hecht K, Carlstedt-Duke J, Stierna P, Gustafsson J, Brönnegârd M, Wikström AC
J Biol Chem. 1997
PubMed ID: 9334248
HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B.
Ayyavoo V, Mahboubi A, Mahalingam S, Ramalingam R, Kudchodkar S, Williams WV, Green DR, Weiner DB
Nat Med. 1997
PubMed ID: 9334723
Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.
Dittmar KD, Demady DR, Stancato LF, Krishna P, Pratt WB
J Biol Chem. 1997
PubMed ID: 9261129
Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation.
Van Houten N, Blake SF, Li EJ, Hallam TA, Chilton DG, Gourley WK, Boise LH, Thompson CB, Thompson EB
Int Immunol. 1997
PubMed ID: 9237103
Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor.
Krstic MD, Rogatsky I, Yamamoto KR, Garabedian MJ
Mol Cell Biol. 1997
PubMed ID: 9199329
Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin.
Silverstein AM, Galigniana MD, Chen MS, Owens-Grillo JK, Chinkers M, Pratt WB
J Biol Chem. 1997
PubMed ID: 9195923
Modulation of hormone-dependent transcriptional activity of the glucocorticoid receptor by the tumor suppressor p53.
Yu C, Yap N, Chen D, Cheng S
Cancer Lett. 1997
PubMed ID: 9215863
Disruption of the glucocorticoid receptor assembly with heat shock protein 90 by a peptidic antiglucocorticoid.
Dao-Phan HP, Formstecher P, Lefebvre P
Mol Endocrinol. 1997
PubMed ID: 9178755
Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor.
Henriksson A, Almlöf T, Ford J, McEwan IJ, Gustafsson JA, Wright AP
Mol Cell Biol. 1997
PubMed ID: 9154805
Androgen and glucocorticoid receptor heterodimer formation. A possible mechanism for mutual inhibition of transcriptional activity.
Chen S, Wang J, Yu G, Liu W, Pearce D
J Biol Chem. 1997
PubMed ID: 9162033
Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation.
Dittmar KD, Pratt WB
J Biol Chem. 1997
PubMed ID: 9148915
Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1.
Thénot S, Henriquet C, Rochefort H, Cavaillès V
J Biol Chem. 1997
PubMed ID: 9115274
Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance.
Koper JW, Stolk RP, de Lange P, Huizenga NA, Molijn GJ, Pols HA, Grobbee DE, Karl M, de Jong FH, Brinkmann AO, Lamberts SW
Hum Genet. 1997
PubMed ID: 9150737
GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors.
Hong H, Kohli K, Garabedian MJ, Stallcup MR
Mol Cell Biol. 1997
PubMed ID: 9111344
Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.
Reyes JC, Muchardt C, Yaniv M
J Cell Biol. 1997
PubMed ID: 9128241
Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta protein.
Wakui H, Wright AP, Gustafsson J, Zilliacus J
J Biol Chem. 1997
PubMed ID: 9079630
Nuclear localisation of calreticulin in vivo is enhanced by its interaction with glucocorticoid receptors.
Roderick HL, Campbell AK, Llewellyn DH
FEBS Lett. 1997
PubMed ID: 9089287
Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor.
Giffin W, Kwast-Welfeld J, Rodda DJ, Préfontaine GG, Traykova-Andonova M, Zhang Y, Weigel NL, Lefebvre YA, Haché RJ
J Biol Chem. 1997
PubMed ID: 9038175
Cloning and expression of the glucocorticoid receptor from the squirrel monkey (Saimiri boliviensis boliviensis), a glucocorticoid-resistant primate.
Reynolds PD, Pittler SJ, Scammell JG
J Clin Endocrinol Metab. 1997
PubMed ID: 9024238
Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex.
Ostlund Farrants AK, Blomquist P, Kwon H, Wrange O
Mol Cell Biol. 1997
PubMed ID: 9001244
Feedback control of glucocorticoid production is established during fetal development.
Reichardt HM, Schütz G
Mol Med. 1996
PubMed ID: 8972488
Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption.
Hesen W, Karst H, Meijer O, Cole TJ, Schmid W, de Kloet ER, Schütz G, Joëls M
J Neurosci. 1996
PubMed ID: 8824317
Functional interactions between Stat5 and the glucocorticoid receptor.
Stöcklin E, Wissler M, Gouilleux F, Groner B
Nature. 1996
PubMed ID: 8878484
The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB.
Agostini I, Navarro JM, Rey F, Bouhamdan M, Spire B, Vigne R, Sire J
J Mol Biol. 1996
PubMed ID: 8800208
Appearance of glucocorticoid receptors in the inner ear of the mouse during development.
Erichsen S, Bagger-Sjöbäck D, Curtis L, Zuo J, Rarey K, Hultcrantz M
Acta Otolaryngol. 1996
PubMed ID: 8908249
The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action, and potential physiologic role.
de Castro M, Elliot S, Kino T, Bamberger C, Karl M, Webster E, Chrousos GP
Mol Med. 1996
PubMed ID: 8898375
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.
Karl M, Lamberts SW, Koper JW, Katz DA, Huizenga NE, Kino T, Haddad BR, Hughes MR, Chrousos GP
Proc Assoc Am Physicians. 1996
PubMed ID: 8863343
Androgens modulate glucocorticoid receptor mRNA, but not mineralocorticoid receptor mRNA levels, in the rat hippocampus.
Kerr JE, Beck SG, Handa RJ
J Neuroendocrinol. 1996
PubMed ID: 8809674
Location of the 9257 and ataxia mutations on mouse chromosome 18.
Griffith AJ, Radice GL, Burgess DL, Kohrman DC, Hansen GM, Justice MJ, Johnson KR, Davisson MT, Meisler MH
Mamm Genome. 1996
PubMed ID: 8662222
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.
Hong H, Kohli K, Trivedi A, Johnson DL, Stallcup MR
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8643509
The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo.
Jaskoll T, Choy HA, Melnick M
Pediatr Res. 1996
PubMed ID: 8726224
The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function.
Oakley RH, Sar M, Cidlowski JA
J Biol Chem. 1996
PubMed ID: 8621628
Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain.
Stancato LF, Silverstein AM, Gitler C, Groner B, Pratt WB
J Biol Chem. 1996
PubMed ID: 8621522
Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor.
Göttlicher M, Heck S, Doucas V, Wade E, Kullmann M, Cato AC, Evans RM, Herrlich P
Steroids. 1996
PubMed ID: 8733011
Molecular genetic analysis of glucocorticoid and mineralocorticoid signaling in development and physiological processes.
Berger SA, Cole TJ, Schmid W, Schütz G
Steroids. 1996
PubMed ID: 8733008
Agonist-free transformation of the glucocorticoid receptor in human B-lymphoma cells.
van den Berg JD, Smets LA, van Rooij H
J Steroid Biochem Mol Biol. 1996
PubMed ID: 8645634
A fraction enriched in a novel glucocorticoid receptor-interacting protein stimulates receptor-dependent transcription in vitro.
Eggert M, Möws CC, Tripier D, Arnold R, Michel J, Nickel J, Schmidt S, Beato M, Renkawitz R
J Biol Chem. 1995
PubMed ID: 8530516
Steroid receptor heterodimerization demonstrated in vitro and in vivo.
Liu W, Wang J, Sauter NK, Pearce D
Proc Natl Acad Sci U S A. 1995
PubMed ID: 8618925
Cloning, expression, and chromosomal localization of a novel cadherin-related protein, protocadherin-3.
Sago H, Kitagawa M, Obata S, Mori N, Taketani S, Rochelle JM, Seldin MF, Davidson M, St John T, Suzuki ST
Genomics. 1995
PubMed ID: 8575755
Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer.
Gaitan D, DeBold CR, Turney MK, Zhou P, Orth DN, Kovacs WJ
Mol Endocrinol. 1995
PubMed ID: 7491111
Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes.
Shafqat S, Velaz-Faircloth M, Henzi VA, Whitney KD, Yang-Feng TL, Seldin MF, Fremeau RT
Mol Pharmacol. 1995
PubMed ID: 7651355
A variant glucocorticoid receptor messenger RNA is expressed in multiple myeloma patients.
Krett NL, Pillay S, Moalli PA, Greipp PR, Rosen ST
Cancer Res. 1995
PubMed ID: 7796394
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.
Cole TJ, Blendy JA, Monaghan AP, Krieglstein K, Schmid W, Aguzzi A, Fantuzzi G, Hummler E, Unsicker K, Schütz G
Genes Dev. 1995
PubMed ID: 7628695
Characterization of the human glucocorticoid receptor promoter.
Nobukuni Y, Smith CL, Hager GL, Detera-Wadleigh SD
Biochemistry. 1995
PubMed ID: 7794935
Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans.
Bamberger CM, Bamberger AM, de Castro M, Chrousos GP
J Clin Invest. 1995
PubMed ID: 7769088
Identification and localization of steroid-binding and nonsteroid-binding forms of the glucocorticoid receptor in the mouse P1798 lymphosarcoma.
Rowan BG, Ip MM
J Steroid Biochem Mol Biol. 1995
PubMed ID: 7748809
Beta-adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung.
Peters MJ, Adcock IM, Brown CR, Barnes PJ
Eur J Pharmacol. 1995
PubMed ID: 7621901
The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product.
Refaeli Y, Levy DN, Weiner DB
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7724608
Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.
Caldenhoven E, Liden J, Wissink S, Van de Stolpe A, Raaijmakers J, Koenderman L, Okret S, Gustafsson JA, Van der Saag PT
Mol Endocrinol. 1995
PubMed ID: 7659084
The CORT-GR signal transduction pathway and CORT-induced cleft palate in H-2 congenic mice.
Jaskoll T, Choy HA, Chen H, Melnick M
J Craniofac Genet Dev Biol. 1995
PubMed ID: 7635930
Evidence for a functional interaction between calmodulin and the glucocorticoid receptor.
Ning YM, Sánchez ER
Biochem Biophys Res Commun. 1995
PubMed ID: 7887964
[Effect of glucocorticoid receptor blockade on pulmonary and renal vascular permeability in scalded rats].
Lin H, Gong X, Zhong J
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1995
PubMed ID: 7648494
Hormone-induced hyperphosphorylation of specific phosphorylated sites in the mouse glucocorticoid receptor.
Bodwell JE, Hu JM, Orti E, Munck A
J Steroid Biochem Mol Biol. 1995
PubMed ID: 7873448
Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors.
Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS
Mol Cell Biol. 1995
PubMed ID: 7823959
Molecular genetic analysis of glucocorticoid signaling during mouse development.
Cole TJ, Blendy JA, Monaghan AP, Schmid W, Aguzzi A, Schütz G
Steroids. 1995
PubMed ID: 7792824
Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.
Seldin MF, Rochelle JM, Tomlinson MG, Wright MD
Immunogenetics. 1995
PubMed ID: 7590978
NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.
Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA
Mol Endocrinol. 1994
PubMed ID: 7877627
Identification and genetic mapping of 151 dispersed members of 16 ribosomal protein multigene families in the mouse.
Johnson KR, Cook SA, Davisson MT
Mamm Genome. 1994
PubMed ID: 7873877
Glucocorticoids, TGF-beta, and embryonic mouse salivary gland morphogenesis.
Jaskoll T, Choy HA, Melnick M
J Craniofac Genet Dev Biol. 1994
PubMed ID: 7883868
Androgen and glucocorticoid receptors interact with insulin degrading enzyme.
Kupfer SR, Wilson EM, French FS
J Biol Chem. 1994
PubMed ID: 8051160
Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency.
Tomomura M, Imamura Y, Tomomura A, Horiuchi M, Saheki T
Biochim Biophys Acta. 1994
PubMed ID: 7914432
The ter primordial germ cell deficiency mutation maps near Grl-1 on mouse chromosome 18.
Sakurai T, Katoh H, Moriwaki K, Noguchi T, Noguchi M
Mamm Genome. 1994
PubMed ID: 8043946
Analysis of CAG trinucleotide repeats from mouse cDNA sequences.
Abbott C, Chambers D
Ann Hum Genet. 1994
PubMed ID: 7979162
Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex.
Czar MJ, Owens-Grillo JK, Dittmar KD, Hutchison KA, Zacharek AM, Leach KL, Deibel MR, Pratt WB
J Biol Chem. 1994
PubMed ID: 8157642
Glucocorticoid receptor expression during the development of the embryonic mouse secondary palate.
Abbott BD, McNabb FM, Lau C
J Craniofac Genet Dev Biol. 1994
PubMed ID: 8071426
Balding: a new mutation on mouse chromosome 18 causing hair loss and immunological defects.
Davisson MT, Cook SA, Johnson KR, Eicher EM
J Hered. 1994
PubMed ID: 8182278
Calcium and protein kinase C regulation of the glucocorticoid receptor in mouse corticotrope tumor cells.
Sheppard KE
J Steroid Biochem Mol Biol. 1994
PubMed ID: 7511409
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor.
Burns K, Duggan B, Atkinson EA, Famulski KS, Nemer M, Bleackley RC, Michalak M
Nature. 1994
PubMed ID: 8107808
Active, interactive, and inactive steroid receptor mutants.
Lanz RB, Hug M, Gola M, Tallone T, Wieland S, Rusconi S
Steroids. 1994
PubMed ID: 8191545
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
Maruyama K, Sugano S
Gene. 1994
PubMed ID: 8125298
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.
Ray A, Prefontaine KE
Proc Natl Acad Sci U S A. 1994
PubMed ID: 8290595
Refined solution structure of the glucocorticoid receptor DNA-binding domain.
Baumann H, Paulsen K, Kovács H, Berglund H, Wright AP, Gustafsson JA, Härd T
Biochemistry. 1993
PubMed ID: 8257681
Messenger RNA phenotyping for semi-quantitative comparison of glucocorticoid receptor transcript levels in the developing embryonic mouse palate.
Lau EC, Li ZQ, Santos V, Slavkin HC
J Steroid Biochem Mol Biol. 1993
PubMed ID: 8274408
Purification and characterization of a macromolecular-translocation inhibitor III of activated glucocorticoid-receptor-complex binding to nuclei from rat liver.
Liu G, Okamoto K, Isohashi F
Eur J Biochem. 1993
PubMed ID: 8269959
Localization of the glucocorticoid receptor in rat liver cells: evidence for plasma membrane bound receptor.
Grote H, Ioannou I, Voigt J, Sekeris CE
Int J Biochem. 1993
PubMed ID: 8288028
A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.
Muchardt C, Yaniv M
EMBO J. 1993
PubMed ID: 8223438
Cloning and expression of mutant glucocorticoid receptors from glucocorticoid-sensitive and -resistant human leukemic cells.
Powers JH, Hillmann AG, Tang DC, Harmon JM
Cancer Res. 1993
PubMed ID: 8358735
Alternatively spliced glucocorticoid receptor messenger RNAs in glucocorticoid-resistant human multiple myeloma cells.
Moalli PA, Pillay S, Krett NL, Rosen ST
Cancer Res. 1993
PubMed ID: 8358712
Receptor accessory factor enhances specific DNA binding of androgen and glucocorticoid receptors.
Kupfer SR, Marschke KB, Wilson EM, French FS
J Biol Chem. 1993
PubMed ID: 8349631
Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein.
Alnemri ES, Fernandes-Alnemri T, Nelki DS, Dudley K, DuBois GC, Litwack G
Proc Natl Acad Sci U S A. 1993
PubMed ID: 8341706
The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock.
Taylor BA, Rowe L, Grieco DA
Genomics. 1993
PubMed ID: 8390965
Identification of the activation-labile gene: a single point mutation in the human glucocorticoid receptor presents as two distinct receptor phenotypes.
Ashraf J, Thompson EB
Mol Endocrinol. 1993
PubMed ID: 8316249
A mutation of the glucocorticoid receptor in primary cortisol resistance.
Malchoff DM, Brufsky A, Reardon G, McDermott P, Javier EC, Bergh CH, Rowe D, Malchoff CD
J Clin Invest. 1993
PubMed ID: 7683692
Heterogeneity in the polyglutamine tract of the glucocorticoid receptor from different rat strains.
Gearing KL, Gustafsson JA, Okret S
Nucleic Acids Res. 1993
PubMed ID: 8493115
Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids.
Imai E, Miner JN, Mitchell JA, Yamamoto KR, Granner DK
J Biol Chem. 1993
PubMed ID: 8449898
Zinc finger mutations that alter domain interactions in the glucocorticoid receptor.
Zandi E, Galli I, Döbbeling U, Rusconi S
J Mol Biol. 1993
PubMed ID: 8450530
Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.
Karl M, Lamberts SW, Detera-Wadleigh SD, Encio IJ, Stratakis CA, Hurley DM, Accili D, Chrousos GP
J Clin Endocrinol Metab. 1993
PubMed ID: 8445027
Typing recombinant inbred mouse strains for microsatellite markers.
Taylor BA, Reifsnyder PC
Mamm Genome. 1993
PubMed ID: 8507976
Lysyl oxidase (Lox) maps between Grl-1 and Adrb-2 on mouse chromosome 18.
Lossie AC, Buckwalter MS, Camper SA
Mamm Genome. 1993
PubMed ID: 8094989
Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.
Luongo C, Gould KA, Su LK, Kinzler KW, Vogelstein B, Dietrich W, Lander ES, Moser AR
Genomics. 1993
PubMed ID: 8094372
Glucocorticoid regulation of alkaline phosphatase, osteocalcin, and proto-oncogenes in normal human osteoblast-like cells.
Subramaniam M, Colvard D, Keeting PE, Rasmussen K, Riggs BL, Spelsberg TC
J Cell Biochem. 1992
PubMed ID: 1469072
Genomic structure and chromosomal mapping of the mouse N-cadherin gene.
Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1528849
At least three promoters direct expression of the mouse glucocorticoid receptor gene.
Strähle U, Schmidt A, Kelsey G, Stewart AF, Cole TJ, Schmid W, Schütz G
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1495961
A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18.
Justice MJ, Gilbert DJ, Kinzler KW, Vogelstein B, Buchberg AM, Ceci JD, Matsuda Y, Chapman VM, Patriotis C, Makris A
Genomics. 1992
PubMed ID: 1354644
A multipoint genetic linkage map of mouse chromosome 18.
Johnson KR, Davisson MT
Genomics. 1992
PubMed ID: 1354640
Rat gene mapping using PCR-analyzed microsatellites.
Serikawa T, Kuramoto T, Hilbert P, Mori M, Yamada J, Dubay CJ, Lindpainter K, Ganten D, Guénet JL, Lathrop GM
Genetics. 1992
PubMed ID: 1628813
Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor.
Cadepond F, Gasc JM, Delahaye F, Jibard N, Schweizer-Groyer G, Segard-Maurel I, Evans R, Baulieu EE
Exp Cell Res. 1992
PubMed ID: 1612132
Association of the transformed glucocorticoid receptor with a cytoskeletal protein complex.
Scherrer LC, Pratt WB
J Steroid Biochem Mol Biol. 1992
PubMed ID: 1562545
Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene.
Pepin MC, Pothier F, Barden N
Nature. 1992
PubMed ID: 1741058
1H NMR studies of DNA recognition by the glucocorticoid receptor: complex of the DNA binding domain with a half-site response element.
Remerowski ML, Kellenbach E, Boelens R, van der Marel GA, van Boom JH, Maler BA, Yamamoto KR, Kaptein R
Biochemistry. 1991
PubMed ID: 1751485
Chronic multifocal osteomyelitis, a new recessive mutation on chromosome 18 of the mouse.
Byrd L, Grossmann M, Potter M, Shen-Ong GL
Genomics. 1991
PubMed ID: 1686018
Creation of "super" glucocorticoid receptors by point mutations in the steroid binding domain.
Chakraborti PK, Garabedian MJ, Yamamoto KR, Simons SS
J Biol Chem. 1991
PubMed ID: 1939229
Identification of the metal coordinating residues in the DNA binding domain of the glucocorticoid receptor by 113Cd-1H heteronuclear NMR spectroscopy.
Kellenbach E, Maler BA, Yamamoto KR, Boelens R, Kaptein R
FEBS Lett. 1991
PubMed ID: 1936288
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA.
Luisi BF, Xu WX, Otwinowski Z, Freedman LP, Yamamoto KR, Sigler PB
Nature. 1991
PubMed ID: 1865905
Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution.
Oakey RJ, Caron MG, Lefkowitz RJ, Seldin MF
Genomics. 1991
PubMed ID: 1676978
Purification of a human glucocorticoid receptor gene promoter-binding protein. Production of polyclonal antibodies against the purified factor.
Leclerc S, Xie BX, Roy R, Govindan MV
J Biol Chem. 1991
PubMed ID: 2026589
Identification of phosphorylated sites in the mouse glucocorticoid receptor.
Bodwell JE, Ortí E, Coull JM, Pappin DJ, Smith LI, Swift F
J Biol Chem. 1991
PubMed ID: 2019585
The genomic structure of the human glucocorticoid receptor.
Encío IJ, Detera-Wadleigh SD
J Biol Chem. 1991
PubMed ID: 1707881
Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
Hurley DM, Accili D, Stratakis CA, Karl M, Vamvakopoulos N, Rorer E, Constantine K, Taylor SI, Chrousos GP
J Clin Invest. 1991
PubMed ID: 1704018
A molecular genetic linkage map of mouse chromosome 18, including spm, Grl-1, Fim-2/c-fms, and Mbp.
Sakai Y, Miyawaki S, Shimizu A, Ohno K, Watanabe T
Biochem Genet. 1991
PubMed ID: 1679325
Human glucocorticoid receptor gene promotor-homologous down regulation.
Govindan MV, Pothier F, Leclerc S, Palaniswami R, Xie B
J Steroid Biochem Mol Biol. 1991
PubMed ID: 1958537
Glucocorticoid receptor in active pulmonary sarcoidosis.
de Carvalho CR, Brentani MM, Karialla RA, Oshima CT, Barbas Filho JV, Saldiva PH
Sarcoidosis. 1990
PubMed ID: 2255800
Solution structure of the glucocorticoid receptor DNA-binding domain.
Härd T, Kellenbach E, Boelens R, Maler BA, Dahlman K, Freedman LP, Carlstedt-Duke J, Yamamoto KR, Gustafsson JA, Kaptein R
Science. 1990
PubMed ID: 2115209
Regional chromosomal assignment of the human glucocorticoid receptor gene to 5q31.
Theriault A, Boyd E, Harrap SB, Hollenberg SM, Connor JM
Hum Genet. 1989
PubMed ID: 2793174
Regulation of glucocorticoid receptor protein and mRNA levels.
Vedeckis WV, Ali M, Allen HR
Cancer Res. 1989
PubMed ID: 2702670
Novel cDNA sequence possibly generated by alternative splicing of a mouse glucocorticoid receptor gene transcript from Shionogi carcinoma 115.
Nohno T, Kasai Y, Saito T
Nucleic Acids Res. 1989
PubMed ID: 2911477
Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms.
Dong Y, Poellinger L, Gustafsson JA, Okret S
Mol Endocrinol. 1988
PubMed ID: 3216865
Metal binding 'finger' structures in the glucocorticoid receptor defined by site-directed mutagenesis.
Severne Y, Wieland S, Schaffner W, Rusconi S
EMBO J. 1988
PubMed ID: 3191912
Cloning and sequence analysis of the rat ventral prostate glucocorticoid receptor cDNA.
Chang CS, Kokontis J, Chang CT, Liao SS
Nucleic Acids Res. 1987
PubMed ID: 3684608
Decreased deoxyribonucleic acid binding of glucocorticoid-receptor complex in cultured skin fibroblasts from a patient with the glucocorticoid resistance syndrome.
Nawata H, Sekiya K, Higuchi K, Kato K, Ibayashi H
J Clin Endocrinol Metab. 1987
PubMed ID: 3597702
Evidence of a gene-dosage effect for the glucocorticoid receptor in trisomy 18 mice.
Vogliolo D, Winking H, Knuppen R
Dev Genet. 1987
PubMed ID: 2901926
The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins.
Danielsen M, Northrop JP, Ringold GM
EMBO J. 1986
PubMed ID: 3780669
Analysis of glucocorticoid unresponsive cell variants using a mouse glucocorticoid receptor complementary DNA clone.
Northrop JP, Danielsen M, Ringold GM
J Biol Chem. 1986
PubMed ID: 3015953
Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA.
Miesfeld R, Rusconi S, Godowski PJ, Maler BA, Okret S, Wikström AC, Gustafsson JA, Yamamoto KR
Cell. 1986
PubMed ID: 3755378
Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product.
Weinberger C, Hollenberg SM, Rosenfeld MG, Evans RM
Nature. 1985
PubMed ID: 3841189
Primary structure and expression of a functional human glucocorticoid receptor cDNA.
Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, Lebo R, Thompson EB, Rosenfeld MG, Evans RM
Nature. 1985
PubMed ID: 2867473
Changes in the pulmonary glucocorticoid receptor content in the course of interstitial disease.
Saldiva PH, Brentani MM, de Carvalho CR, Auler Júnior JO, Calheiros DF, Pacheco MM
Chest. 1985
PubMed ID: 4028852
Interaction of rat liver glucocorticoid receptor with heparin.
Weisz A, Puca GA, Masucci MT, Masi C, Pagnotta R, Petrillo A, Sica V
Biochemistry. 1984
PubMed ID: 6509026
Comparison between different rabbit antisera against the glucocorticoid receptor.
Okret S
J Steroid Biochem. 1983
PubMed ID: 6621034
Characterization of an antiserum against the glucocorticoid receptor.
Okret S, Carlstedt-Duke J, Wrange O, Carlström K, Gustafsson JA
Biochim Biophys Acta. 1981
PubMed ID: 7295795
Glucocorticoid receptors in normal human eosinophils: comparison with neutrophils.
Peterson AP, Altman LC, Hill JS, Gosney K, Kadin ME
J Allergy Clin Immunol. 1981
PubMed ID: 7264103
[Glucocorticoid-receptor complexes of rat liver. I. Kinetic and equilibrium parameters of their interaction with DNA: ionic strength and temperature dependence]
Romanov GA, Romanova NA, Rozen VB, Vaniushin BF
Mol Biol (Mosk). 1981
PubMed ID: 7254211
Hormone production by cultures of small-cell carcinoma of the lung.
Sorenson GD, Pettengill OS, Brinck-Johnsen T, Cate CC, Maurer LH
Cancer. 1981
PubMed ID: 6261922
Chromosome assignment of a murine glucocorticoid receptor gene (Grl-1) using intraspecies somatic cell hybrids.
Francke U, Gehring U
Cell. 1980
PubMed ID: 7460010
Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung.
Pettengill OS, Sorenson GD, Wurster-Hill DH, Curphey TJ, Noll WW, Cate CC, Maurer LH
Cancer. 1980
PubMed ID: 6266631
[Balloon probe for the removal of emboli and thrombi]
Plotkin LL, Labutin AL, Lebedev LV, Khanukov LA, Zelikson OS
Med Tekh. 1975
PubMed ID: 1152650

Model Organism Phenotype Links from MGI Top Help

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	Human	Mouse	Rat
Entrez Gene	2908	14815	24413
EnsEMBL Gene(s)	ENSG00000113580	ENSMUSG00000024431	ENSRNOG00000014096
Unigene	Hs.122926	Mm.129481	Rn.90070
Homologene	NR3C1	Nr3c1	Nr3c1
OMIM	138040	N/A	N/A
GeneCards	NR3C1	N/A	N/A
Beta Cell Genomics	DT.100786784 DT.100786795 DT.102832223 DT.120796451 DT.120796478 DT.120796495 DT.120796547 DT.120796581 DT.120796597 DT.120796608 DT.120796627 DT.85105550 DT.95269160 DT.95296381 DT.99998911	DT.101309837 DT.493344 DT.99867367	N/A
Reactome	P04150	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	2908	14815	24413

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Interactor	Interactor	Sources	Classification	Pubmed IDs
NR3C1	ADA	HPRD, BioGRID	empirical	9154805
NR3C1	NR2E3	BioGRID	empirical	20211142
NR3C1	HDAC6	BioGRID	empirical	20018896
NR3C1	RANBP9	BioGRID	empirical	12361945
NR3C1	ARPC5	BioGRID	empirical	10508170
NR3C1	TRIM28	HPRD, BioGRID	empirical	9742105
NR3C1	STUB1	BioGRID	empirical	11146632
NR3C1	DNAJA2	IntAct	empirical	16619302
NR3C1	RBM14	BioGRID	empirical	20211142
NR3C1	NCOA2	HPRD	empirical	12151000
NR3C1	CEBPA	HPRD, BioGRID	empirical	11818365 9817600
NR3C1	CEBPB	HPRD	empirical	9817600
NR3C1	CENPB	IntAct	empirical	20195357
NR3C1	PTGES3	HPRD, BioGRID	empirical	10691735 16087666
NR3C1	PPARGC1A	HPRD, BioGRID	empirical	10713165
NR3C1	COPS6	HPRD	empirical	12237292
NR3C1	ZHX1	IntAct	empirical	20195357
NR3C1	ECD	HPRD, BioGRID	empirical	9928932
NR3C1	CLU	IntAct	empirical	20195357
NR3C1	CLTC	IntAct	empirical	20195357
NR3C1	ALDH16A1	IntAct	empirical	16619302
NR3C1	CREB1	HPRD, BioGRID	empirical	7621901 8449898
NR3C1	CREBBP	HPRD, BioGRID	empirical	9649342 9590696 20018896
NR3C1	TCEAL2	IntAct	empirical	20195357
NR3C1	ZNF483	IntAct	empirical	20195357
NR3C1	DAXX	BioGRID	empirical	12595526
NR3C1	DYNC1I1	IntAct	empirical	11751894
NR3C1	AHSG	IntAct	empirical	16619302
NR3C1	EIF4A2	IntAct	empirical	20195357
NR3C1	EP300	BioGRID	empirical	17884810
NR3C1	EPB41L2	IntAct	empirical	20195357
NR3C1	NR2F6	HPRD, MIPS, BioGRID	empirical	10713182
NR3C1	ETS1	HPRD	empirical	11279115
NR3C1	ETS2	HPRD, BioGRID	empirical	11279115
NR3C1	ALB	IntAct	empirical	16619302
NR3C1	FABP1	IntAct	empirical	16619302
NR3C1	ZBTB9	BioGRID	empirical	20211142
NR3C1	FGB	IntAct	empirical	16619302
NR3C1	MAPK15	HPRD	empirical	16624805
NR3C1	FKBP4	HPRD, IntAct, BioGRID	empirical	8341706 11751894
NR3C1	FKBP5	IntAct	empirical	11751894
NR3C1	NCOA6	HPRD, BioGRID	empirical	10866662 10567404
NR3C1	EPB41L3	IntAct	empirical	20195357
NR3C1	PRRC2C	IntAct	empirical	20195357
NR3C1	NEDD4L	BioGRID	empirical	9649342
NR3C1	GRIP1	HPRD, MINT, BioGRID	empirical	16362036 16423881
NR3C1	PHF3	IntAct	empirical	20195357
NR3C1	MAFF	BioGRID	empirical	20211142
NR3C1	PRPF6	HPRD	empirical	12039962
NR3C1	FTH1	BioGRID	empirical	15604093
NR3C1	FYN	HPRD	empirical	16888650
NR3C1	ZBTB20	BioGRID	empirical	20211142
NR3C1	PELP1	HPRD	empirical	12415108
NR3C1	SFN	HPRD, MINT, BioGRID	empirical	12730237
NR3C1	NR3C1	HPRD, IntAct, BioGRID	empirical	12773573 9482670 10364267 12917342 12151000
NR3C1	SLC25A4	HPRD	empirical	12039962
NR3C1	PSMC3IP	HPRD, BioGRID	empirical	11739747
NR3C1	HBA1	IntAct	empirical	16619302
NR3C1	HDAC1	BioGRID	empirical	16762839 15826950
NR3C1	HDAC2	BioGRID	empirical	10958685
NR3C1	HMGB1	BioGRID	empirical	9671457
NR3C1	HMGB2	BioGRID	empirical	9671457
NR3C1	HMOX2	BioGRID	empirical	21900206
NR3C1	NR4A1	BioGRID	empirical	21900206
NR3C1	ONECUT1	HPRD, BioGRID	empirical	10430878
NR3C1	HNRNPA1	BioGRID	empirical	15604093
NR3C1	HNRNPU	HPRD, MIPS, BioGRID	empirical	9353307
NR3C1	HOXB1	BioGRID	empirical	12487626
NR3C1	HOXB8	BioGRID	empirical	20211142
NR3C1	DNAJA1	IntAct	empirical	16619302
NR3C1	HSPA1A	HPRD	empirical	12093808
NR3C1	HSP90AA1	HPRD, IntAct, BioGRID	empirical	8898375 9334248 8645634 10066374 8621522 20195357 10903152 12093808 16087666 15916966 9195923
NR3C1	HSP90AB1	IntAct, BioGRID	empirical	16619302 11751894 9261129
NR3C1	HSPD1	BioGRID	empirical	10508170
NR3C1	IDE	HPRD	empirical	8051160
NR3C1	IFNGR2	HPRD	empirical	8349631
NR3C1	TUBB2B	IntAct	empirical	16619302
NR3C1	AR	HPRD	empirical	9162033
NR3C1	JUN	HPRD, BioGRID	empirical	8733011 7823959 14522952
NR3C1	KPNA2	HPRD	empirical	12933681
NR3C1	SUMO4	HPRD	empirical	16236267
NR3C1	KTN1	IntAct	empirical	20195357
NR3C1	LASP1	IntAct	empirical	16619302
NR3C1	LCK	HPRD, MINT, BioGRID	empirical	16888650
NR3C1	SMAD3	HPRD, BioGRID	empirical	12902338 10518526
NR3C1	MDM2	HPRD, BioGRID	empirical	11562347
NR3C1	MLL	IntAct	empirical	20195357
NR3C1	NR3C2	HPRD, BioGRID	empirical	11154266
NR3C1	MSX2	BioGRID	empirical	20211142
NR3C1	NCL	HPRD, BioGRID	empirical	11162542 8530516
NR3C1	NFKB1	HPRD, BioGRID	empirical	7823959 8290595 16380507
NR3C1	NFKB2	HPRD, BioGRID	empirical	7823959
NR3C1	ATP1B1	IntAct	empirical	20195357
NR3C1	PRDX1	IntAct	empirical	16619302
NR3C1	PAWR	IntAct	empirical	16619302
NR3C1	PBX1	HPRD, BioGRID	empirical	12487626
NR3C1	POLR1D	IntAct	empirical	21988832
NR3C1	CWC15	IntAct	empirical	20195357
NR3C1	ACP1	IntAct	empirical	20195357
NR3C1	PML	BioGRID	empirical	20211142
NR3C1	POU1F1	HPRD, BioGRID	empirical	9426156
NR3C1	POU2F1	HPRD, BioGRID	empirical	10490647 10480874 9584182 14522952 11096094 20211142
NR3C1	POU2F2	HPRD, BioGRID	empirical	10490647 10480874 9584182
NR3C1	MED1	BioGRID, Reactome	empirical	11266503 10508170 10542397 10235266 16751179 15896744 15175151 11865025 9653119
NR3C1	PPP3CA	IntAct	empirical	20195357
NR3C1	PPP6C	IntAct	empirical	16619302
NR3C1	OSGEP	BioGRID	empirical	21900206
NR3C1	PRKACA	HPRD	empirical	11027313
NR3C1	DCAF6	HPRD	empirical	15784617
NR3C1	PRKDC	HPRD	empirical	9038175
NR3C1	MAPK1	HPRD	empirical	12351702 9199329
NR3C1	MAPK8	HPRD	empirical	12351702 9199329
NR3C1	MAP2K2	IntAct	empirical	16619302
NR3C1	BAG1	HPRD, BioGRID	empirical	9603979 11101523 10477749
NR3C1	PTMS	HPRD, BioGRID	empirical	10601862 16150697
NR3C1	PTPRN2	IntAct	empirical	20195357
NR3C1	RAD9A	BioGRID	empirical	14966297
NR3C1	RAF1	HPRD, BioGRID	empirical	11005817
NR3C1	RAN	BioGRID	empirical	10508170
NR3C1	RARA	HPRD	empirical	17641689
NR3C1	RARB	BioGRID	empirical	20211142
NR3C1	KDM5A	HPRD	empirical	11358960
NR3C1	RELA	HPRD, IntAct, BioGRID	empirical	10995388 7659084 8290595 16619302
NR3C1	CLIP1	IntAct	empirical	20195357
NR3C1	RXRB	BioGRID	empirical	20211142
NR3C1	BHMT	IntAct	empirical	16619302
NR3C1	DMRTC2	BioGRID	empirical	20211142
NR3C1	TSPYL2	IntAct	empirical	20195357
NR3C1	SET	BioGRID	empirical	18096310
NR3C1	SFPQ	BioGRID	empirical	19339282
NR3C1	SRSF5	IntAct	empirical	20195357
NR3C1	SMARCA2	HPRD, IntAct, BioGRID	empirical	8223438 20195357 17043312
NR3C1	SMARCA4	HPRD, IntAct, BioGRID	empirical	9590696 12917342 10688647 9128241 17387179
NR3C1	SMARCB1	HPRD	empirical	10688647
NR3C1	SMARCC1	HPRD, IntAct, BioGRID	empirical	9590696 12917342
NR3C1	SMARCD1	HPRD, IntAct, BioGRID	empirical	12917342
NR3C1	SMARCE1	HPRD, IntAct, BioGRID	empirical	12917342
NR3C1	SRC	BioGRID	empirical	16423881
NR3C1	SSB	IntAct	empirical	20195357
NR3C1	STAT3	HPRD, BioGRID	empirical	14522952 9388192
NR3C1	STAT5A	HPRD, MIPS	empirical	9528750
NR3C1	STAT5B	HPRD, MIPS, BioGRID	empirical	11158330 8878484 9528750
NR3C1	SVIL	BioGRID	empirical	11792840
NR3C1	SYT1	HPRD	empirical	16143103
NR3C1	TADA2A	BioGRID	empirical	9649342
NR3C1	TBP	HPRD, BioGRID	empirical	9649342
NR3C1	TCEB1	IntAct	empirical	16619302
NR3C1	TDG	BioGRID	empirical	12874288
NR3C1	NR2F2	HPRD	empirical	14739255
NR3C1	TGFB1I1	HPRD, BioGRID	empirical	10848625
NR3C1	TMF1	IntAct	empirical	20195357
NR3C1	TP53	HPRD, BioGRID	empirical	11080152 11562347
NR3C1	TSG101	HPRD, BioGRID	empirical	10508170
NR3C1	TTC3	IntAct	empirical	20195357
NR3C1	TTPA	IntAct	empirical	16619302
NR3C1	TXN	HPRD, BioGRID	empirical	9915858
NR3C1	UBB	HPRD	empirical	11146632
NR3C1	UBC	BioGRID	empirical	12490527 11562347 11555652 11146632
NR3C1	UBE2I	HPRD, BioGRID	empirical	11812797
NR3C1	SUMO1	HPRD	empirical	12193561 12144530
NR3C1	YWHAH	HPRD, BioGRID	empirical	9079630 12730237 11266503
NR3C1	ZBTB16	HPRD, BioGRID	empirical	14521715
NR3C1	DAP3	HPRD, BioGRID	empirical	12099703 10903152
NR3C1	TUBA1A	IntAct	empirical	16619302
NR3C1	DDX54	HPRD, BioGRID	empirical	12466272
NR3C1	ALDH5A1	IntAct	empirical	20195357
NR3C1	ZBTB3	BioGRID	empirical	20211142
NR3C1	CALM1	HPRD	empirical	7887964
NR3C1	CHD9	HPRD	empirical	16523501
NR3C1	NCOA4	BioGRID	empirical	9892017 10517667
NR3C1	CALR	HPRD, BioGRID	empirical	8107808 9089287
NR3C1	ANP32A	IntAct	empirical	20195357
NR3C1	MED25	MINT, BioGRID	empirical	17641689
NR3C1	NCOA3	IntAct	empirical	12917342
NR3C1	NRIP1	HPRD, BioGRID	empirical	12773562 10364267 11266503 10659697
NR3C1	CUL2	IntAct	empirical	20195357
NR3C1	ZNF496	BioGRID	empirical	20211142
NR3C1	NCOA1	HPRD, IntAct, MIPS, BioGRID	empirical	12917342 12118039 12569182 10731636 11266503 10659697 9590696
NR3C1	TRIM24	HPRD, BioGRID	empirical	9115274
NR3C1	CD3D	MINT	empirical	16888650
NR3C1	CD3G	BioGRID	empirical	16888650
NR3C1	CD4	MINT, BioGRID	empirical	16888650
NR3C1	RPS6KA5	MINT	empirical	18511904
NR3C1	MED14	HPRD, BioGRID	empirical	10508170
NR3C1	TJP2	IntAct	empirical	20195357
NR3C1	HOMER2	IntAct	empirical	16619302
NR3C1	RNF14	HPRD	empirical	10085091
NR3C1	NCOR1	HPRD, BioGRID	empirical	12011091 12569182 15870285 15016838
NR3C1	NCOR2	HPRD	empirical	12011091
NR3C1	EIF5B	IntAct	empirical	20195357
NR3C1	KIAA0408	IntAct	empirical	20195357
NR3C1	MVP	IntAct	empirical	16619302
NR3C1	THRAP3	IntAct	empirical	20195357