ERCC2

Summary Top Help

Gene Description:

excision repair cross-complementing rodent repair deficiency, complementation group 2

Synonyms:

Ercc-2, CXPD, COFS2, AU020867, XPD, EM9, TTD, AW240756, ERCC2, Ercc2, AA407812

Orthologs:

Human ERCC2 (protein-coding), Mouse Ercc2 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr19:45854246..45873876 (19.63 kb) View in Genome Browser

(Mouse) NCBIM37 - chr7:19967359..19981043 (13.68 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for ERCC2:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas
								no data	no data	no data	no data	no data

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for ERCC2:

The ERCC2 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.

The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.

Interactor	Interactor	Sources	Classification	Pubmed IDs
ERCC2	CDK7	HPRD, BioGRID	empirical	11445587 8692841
ERCC2	DARS	Sanger Interaction Map	predicted	15345047
ERCC2	ACSF3	Sanger Interaction Map	predicted	15345047
ERCC2	ERCC2	HPRD	empirical	11266437 15220921 11062469
ERCC2	ERCC3	HPRD, BioGRID, Reactome	empirical	8652557 15220921 9118947 8152490
ERCC2	ERCC5	HPRD, BioGRID	empirical	8652557
ERCC2	ERCC6	BioGRID	empirical	20541997
ERCC2	GTF2H1	HPRD, BioGRID, Reactome	empirical	9130708 8652557 8152490
ERCC2	GTF2H2	HPRD, BioGRID	empirical	9771713 11062469 12820975
ERCC2	GTF2H3	BioGRID, Reactome	empirical	21157430
ERCC2	GTF2H4	Reactome	predicted
ERCC2	NARS	Sanger Interaction Map	predicted	15345047
ERCC2	HERC5	BioGRID	empirical	16884686
ERCC2	EXOSC10	Sanger Interaction Map	predicted	15345047
ERCC2	PIDD	BioGRID	empirical	21415862
ERCC2	ATF7IP	BioGRID	empirical	19106100
ERCC2	RAD51	HPRD	empirical	12359753
ERCC2	MMS19	Sanger Interaction Map	predicted	15345047
ERCC2	TP53	BioGRID	empirical	7663514
ERCC2	UBC	BioGRID	empirical	21139048 21890473 21906983
ERCC2	TRIM25	BioGRID	empirical	16884686
ERCC2	NARS2	Sanger Interaction Map	predicted	15345047
ERCC2	GPT2	Sanger Interaction Map	predicted	15345047
ERCC2	CCBL1	Sanger Interaction Map	predicted	15345047
ERCC2	CCNH	BioGRID	empirical	8692842
ERCC2	ISG15	BioGRID	empirical	16884686
ERCC2	CDK1	HPRD	empirical	8652557

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 2

Biocarta: None available

Reactome: 30

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 68

Cell cycle checkpoint	GO:0000075
Nucleotide binding	GO:0000166
SSL2-core TFIIH complex	GO:0000441
Nucleotide-excision repair, DNA damage removal	GO:0000718
Response to hypoxia	GO:0001666
In utero embryonic development	GO:0001701
DNA binding	GO:0003677
ATP-dependent DNA helicase activity	GO:0004003
Helicase activity	GO:0004386
Protein kinase activity	GO:0004672
Protein binding	GO:0005515
ATP binding	GO:0005524
Nucleus	GO:0005634
Nucleoplasm	GO:0005654
Holo TFIIH complex	GO:0005675
Cytoplasm	GO:0005737
Spindle	GO:0005819
Cytoskeleton	GO:0005856
Nucleobase-containing compound metabolic process	GO:0006139
DNA repair	GO:0006281
Transcription-coupled nucleotide-excision repair	GO:0006283
Nucleotide-excision repair	GO:0006289
Transcription from RNA polymerase I promoter	GO:0006360
Transcription initiation from RNA polymerase I promoter	GO:0006361
Transcription elongation from RNA polymerase I promoter	GO:0006362
Termination of RNA polymerase I transcription	GO:0006363
Transcription from RNA polymerase II promoter	GO:0006366
Transcription initiation from RNA polymerase II promoter	GO:0006367
Transcription elongation from RNA polymerase II promoter	GO:0006368
MRNA capping	GO:0006370
Protein phosphorylation	GO:0006468
Induction of apoptosis	GO:0006917
Response to oxidative stress	GO:0006979
Chromosome segregation	GO:0007059
Aging	GO:0007568
Protein C-terminus binding	GO:0008022
DNA-dependent ATPase activity	GO:0008094
Cell proliferation	GO:0008283
RNA polymerase II carboxy-terminal domain kinase activity	GO:0008353
UV protection	GO:0009650
Post-embryonic development	GO:0009791
Gene expression	GO:0010467
Viral reproduction	GO:0016032
Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818
Cyclin-dependent protein kinase activating kinase holoenzyme complex	GO:0019907
Spinal cord development	GO:0021510
Extracellular matrix organization	GO:0030198
Bone mineralization	GO:0030282
Central nervous system myelin formation	GO:0032289
Nucleotide-excision repair, DNA incision	GO:0033683
Multicellular organism growth	GO:0035264
Hair cell differentiation	GO:0035315
Embryonic cleavage	GO:0040016
Negative regulation of apoptotic process	GO:0043066
5'-3' DNA helicase activity	GO:0043139
Erythrocyte maturation	GO:0043249
Positive regulation of DNA binding	GO:0043388
Skin development	GO:0043588
Interspecies interaction between organisms	GO:0044419
Positive regulation of transcription, DNA-dependent	GO:0045893
Positive regulation of transcription from RNA polymerase II promoter	GO:0045944
Metal ion binding	GO:0046872
Protein N-terminus binding	GO:0047485
Hair follicle maturation	GO:0048820
Positive regulation of viral transcription	GO:0050434
Iron-sulfur cluster binding	GO:0051536
Hemopoietic stem cell differentiation	GO:0060218
MMXD complex	GO:0071817

KEGG Network: 2
Basal transcription factors	Human - 3022	Mouse - 3022
Nucleotide excision repair	Human - 3420	Mouse - 3420

Biocarta: None available

Reactome: 30
DNA Repair	REACT_216
Dual incision reaction in GG-NER	REACT_311
Dual incision reaction in TC-NER	REACT_2222
Formation and Maturation of mRNA Transcript	REACT_2039
Formation of incision complex in GG-NER	REACT_257
Formation of RNA Pol II elongation complex	REACT_1845
Formation of the Early Elongation Complex	REACT_846
Formation of transcription-coupled NER (TC-NER) repair complex	REACT_1941
Gene Expression	REACT_71
Global Genomic NER (GG-NER)	REACT_2253
mRNA Capping	REACT_1470
mRNA Processing	REACT_1675
Nucleotide Excision Repair	REACT_1826
RNA Pol II CTD phosphorylation and interaction with CE	REACT_975
RNA Polymerase I Chain Elongation	REACT_2204
RNA Polymerase I Promoter Clearance	REACT_1974
RNA Polymerase I Promoter Escape	REACT_1913
RNA Polymerase I Transcription	REACT_1309
RNA Polymerase I Transcription Initiation	REACT_953
RNA Polymerase I Transcription Termination	REACT_1074
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	REACT_21352
RNA Polymerase II Pre-transcription Events	REACT_22107
RNA Polymerase II Promoter Escape	REACT_2089
RNA Polymerase II Transcription	REACT_1366
RNA Polymerase II Transcription Elongation	REACT_833
RNA Polymerase II Transcription Initiation	REACT_1851
RNA Polymerase II Transcription Initiation And Promoter Clearance	REACT_834
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	REACT_1655
Transcription	REACT_1788
Transcription-coupled NER (TC-NER)	REACT_1628

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 68
Cell cycle checkpoint	GO:0000075
Nucleotide binding	GO:0000166
SSL2-core TFIIH complex	GO:0000441
Nucleotide-excision repair, DNA damage removal	GO:0000718
Response to hypoxia	GO:0001666
In utero embryonic development	GO:0001701
DNA binding	GO:0003677
ATP-dependent DNA helicase activity	GO:0004003
Helicase activity	GO:0004386
Protein kinase activity	GO:0004672
Protein binding	GO:0005515
ATP binding	GO:0005524
Nucleus	GO:0005634
Nucleoplasm	GO:0005654
Holo TFIIH complex	GO:0005675
Cytoplasm	GO:0005737
Spindle	GO:0005819
Cytoskeleton	GO:0005856
Nucleobase-containing compound metabolic process	GO:0006139
DNA repair	GO:0006281
Transcription-coupled nucleotide-excision repair	GO:0006283
Nucleotide-excision repair	GO:0006289
Transcription from RNA polymerase I promoter	GO:0006360
Transcription initiation from RNA polymerase I promoter	GO:0006361
Transcription elongation from RNA polymerase I promoter	GO:0006362
Termination of RNA polymerase I transcription	GO:0006363
Transcription from RNA polymerase II promoter	GO:0006366
Transcription initiation from RNA polymerase II promoter	GO:0006367
Transcription elongation from RNA polymerase II promoter	GO:0006368
MRNA capping	GO:0006370
Protein phosphorylation	GO:0006468
Induction of apoptosis	GO:0006917
Response to oxidative stress	GO:0006979
Chromosome segregation	GO:0007059
Aging	GO:0007568
Protein C-terminus binding	GO:0008022
DNA-dependent ATPase activity	GO:0008094
Cell proliferation	GO:0008283
RNA polymerase II carboxy-terminal domain kinase activity	GO:0008353
UV protection	GO:0009650
Post-embryonic development	GO:0009791
Gene expression	GO:0010467
Viral reproduction	GO:0016032
Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818
Cyclin-dependent protein kinase activating kinase holoenzyme complex	GO:0019907
Spinal cord development	GO:0021510
Extracellular matrix organization	GO:0030198
Bone mineralization	GO:0030282
Central nervous system myelin formation	GO:0032289
Nucleotide-excision repair, DNA incision	GO:0033683
Multicellular organism growth	GO:0035264
Hair cell differentiation	GO:0035315
Embryonic cleavage	GO:0040016
Negative regulation of apoptotic process	GO:0043066
5'-3' DNA helicase activity	GO:0043139
Erythrocyte maturation	GO:0043249
Positive regulation of DNA binding	GO:0043388
Skin development	GO:0043588
Interspecies interaction between organisms	GO:0044419
Positive regulation of transcription, DNA-dependent	GO:0045893
Positive regulation of transcription from RNA polymerase II promoter	GO:0045944
Metal ion binding	GO:0046872
Protein N-terminus binding	GO:0047485
Hair follicle maturation	GO:0048820
Positive regulation of viral transcription	GO:0050434
Iron-sulfur cluster binding	GO:0051536
Hemopoietic stem cell differentiation	GO:0060218
MMXD complex	GO:0071817

Publications from PubMed Top Help

Publications: 600

Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India.
Kumar A, Pant MC, Singh HS, Khandelwal S
Tumour Biol. 2012
PubMed ID: 22081374
Haplotypes of DNA repair and cell cycle control genes, X-ray exposure, and risk of childhood acute lymphoblastic leukemia.
Chokkalingam AP, Bartley K, Wiemels JL, Metayer C, Barcellos LF, Hansen HM, Aldrich MC, Guha N, Urayama KY, Scélo G, Chang JS, Month SR, Wiencke JK, Buffler PA
Cancer Causes Control. 2011
PubMed ID: 21987080
Association of hOGG1 and XPD polymorphisms with urothelial carcinoma in Taiwan.
Wang YH, Yeh SD, Shen KH, Shen CH, Tung MC, Liu CT, Chiou HY
Anticancer Res. 2011
PubMed ID: 22110223
DNA repair enzyme polymorphisms and oxidative stress in a Turkish population with gastric carcinoma.
Engin AB, Karahalil B, Engin A, Karakaya AE
Mol Biol Rep. 2011
PubMed ID: 21390502
Lack of association between XPD Lys751Gln and Asp312Asn polymorphisms and colorectal cancer risk: a meta-analysis of case-control studies.
Zhang Y, Ding D, Wang X, Zhu Z, Huang M, He X
Int J Colorectal Dis. 2011
PubMed ID: 21541661
No association between DNA repair gene (XPD, XRCC1, and XRCC4) polymorphisms and nonsyndromic microtia in Turkish patients.
Sever T, Buyukgural B, Pehlivan S, Rosti RO, Bekerecioglu M
Plast Reconstr Surg. 2011
PubMed ID: 21788800
HapMap-based study of a region encompassing ERCC1 and ERCC2 related to lung cancer susceptibility in a Chinese population.
Yin J, Vogel U, Ma Y, Qi R, Wang H, Yue L, Liang D, Wang C, Li X, Song T
Mutat Res. 2011
PubMed ID: 21601580
DNA repair gene ERCC2 polymorphisms and risk of squamous cell carcinoma of the head and neck.
Gugatschka M, Dehchamani D, Wascher TC, Friedrich G, Renner W
Exp Mol Pathol. 2011
PubMed ID: 21419115
[The peculiarities of polymorphism of XPD and XRCC1 repair genes in cells of Down and Ehlers-Danlo syndrome patients characterized by increased radiosensitivity].
Shagirova ZhM, Kurbatova LA, Shulenina LV, Semiachkina AN, Mikhaĭlov VF, Zasukhina GD
Radiats Biol Radioecol. 2011
PubMed ID: 21950097
Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients.
Iranzo V, Sirera R, Bremnes RM, Blasco A, Jantus-Lewintre E, Tarón M, Berrocal A, Blasco S, Caballero C, Del Pozo N, Rosell R, Camps C
Clin Lung Cancer. 2011
PubMed ID: 21726821
Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related cataract development in Han Chinese.
Luo YF, Wang BB, Zhou Z, Ding XC, Hu SS, Zhou GK, Ma X, Qi YH
Curr Eye Res. 2011
PubMed ID: 21599457
Assessment of XPD Lys751Gln and XRCC1 T-77C polymorphisms in advanced non-small-cell lung cancer patients treated with platinum-based chemotherapy.
Liu L, Yuan P, Wu C, Zhang X, Wang F, Guo H, Zhong R, Xu Y, Wu J, Yu D, Wu T, Zhang X, Nie S, Miao X, Lin D
Lung Cancer. 2011
PubMed ID: 21129812
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Impact of thymidylate synthase promoter and DNA repair gene polymorphisms on susceptibility to childhood acute lymphoblastic leukemia.
Canalle R, Silveira VS, Scrideli CA, Queiroz RG, Lopes LF, Tone LG
Leuk Lymphoma. 2011
PubMed ID: 21463130
PIDD orchestrates translesion DNA synthesis in response to UV irradiation.
Logette E, Schuepbach-Mallepell S, Eckert MJ, Leo XH, Jaccard B, Manzl C, Tardivel A, Villunger A, Quadroni M, Gaide O, Tschopp J
Cell Death Differ. 2011
PubMed ID: 21415862
ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln polymorphisms are independent prognostic factors for the clinical course of melanoma.
Schrama D, Scherer D, Schneider M, Zapatka M, Bröcker EB, Schadendorf D, Ugurel S, Kumar R, Becker JC
J Invest Dermatol. 2011
PubMed ID: 21390047
Impact of ERCC2 gene polymorphism on HIV-1 disease progression to AIDS among North Indian HIV patients.
Sobti RC, Berhane N, Mahdi SA, Kler R, Hosseini SA, Kuttiat V, Wanchu A
Mol Biol Rep. 2011
PubMed ID: 20127180
XPD Lys751Gln polymorphism and esophageal cancer risk: a meta-analysis involving 2288 cases and 4096 controls.
Yuan L, Cui D, Zhao EJ, Jia CZ, Wang LD, Lu WQ
World J Gastroenterol. 2011
PubMed ID: 21633601
ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis.
Yin M, Yan J, Martinez-Balibrea E, Graziano F, Lenz HJ, Kim HJ, Robert J, Im SA, Wang WS, Etienne-Grimaldi MC, Wei Q
Clin Cancer Res. 2011
PubMed ID: 21278243
Predictive value of ERCC1 and XPD polymorphism in patients with advanced non-small cell lung cancer receiving platinum-based chemotherapy: a systematic review and meta-analysis.
Wei SZ, Zhan P, Shi MQ, Shi Y, Qian Q, Yu LK, Song Y
Med Oncol. 2011
PubMed ID: 20143185
XPB mediated retroviral cDNA degradation coincides with entry to the nucleus.
Yoder KE, Roddick W, Hoellerbauer P, Fishel R
Virology. 2011
PubMed ID: 21167544
The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process.
Chymkowitch P, Le May N, Charneau P, Compe E, Egly JM
EMBO J. 2011
PubMed ID: 21157430
DNA repair gene polymorphisms at XRCC1, XRCC3, XPD, and OGG1 loci in Maharashtrian population of central India.
Pramanik S, Devi S, Chowdhary S, Surendran ST, Krishnamurthi K, Chakrabarti T
Chemosphere. 2011
PubMed ID: 21183201
[Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship].
Hou X, Zhao Y, Zheng YR, Wang JJ, Wu ZC, Sun JH
Zhonghua Yi Xue Za Zhi. 2011
PubMed ID: 21418965
Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms.
Diamond HR, Ornellas MH, Orfao A, Gomes BE, Campos MM, Fernandez TS, da Silva RI, Alves G, Lage C, da Silva DA, Moellmann-Coelho A, da Cruz GS, Bouzas LF, Abdelhay E
J Hematol Oncol. 2011
PubMed ID: 21951951
Lack of any relationship between chemotherapy toxicity in non-small cell lung cancer cases and polymorphisms in XRCC1 codon 399 or XPD codon 751.
Li Y, Huang XE, Jin GF, Shen HB, Xu L
Asian Pac J Cancer Prev. 2011
PubMed ID: 21627375
XRCC1 and XPD DNA repair gene polymorphisms: a potential risk factor for glaucoma in the Pakistani population.
Yousaf S, Khan MI, Micheal S, Akhtar F, Ali SH, Riaz M, Ali M, Lall P, Waheed NK, den Hollander AI, Ahmed A, Qamar R
Mol Vis. 2011
PubMed ID: 21617750
The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development.
Rouissi K, Bahria IB, Bougatef K, Marrakchi R, Stambouli N, Hamdi K, Cherif M, Ben Slama MR, Sfaxi M, Othman FB, Chebil M, Elgaaied AB, Ouerhani S
BMC Cancer. 2011
PubMed ID: 21426550
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Polymorphisms in two DNA repair genes (XPD and XRCC1)--association with age related cataracts.
Padma G, Mamata M, Reddy KR, Padma T
Mol Vis. 2011
PubMed ID: 21245954
ERCC2/XPD polymorphisms and lung cancer risk.
Christiani DC
J Thorac Oncol. 2011
PubMed ID: 21178723
Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy.
Huang MY, Huang ML, Chen MJ, Lu CY, Chen CF, Tsai PC, Chuang SC, Hou MF, Lin SR, Wang JY
Pharmacogenet Genomics. 2011
PubMed ID: 21057378
Genetic modifiers of carcinogen DNA adducts in target lung and peripheral blood mononuclear cells.
Lee MS, Su L, Mark EJ, Wain JC, Christiani DC
Carcinogenesis. 2010
PubMed ID: 20935060
No evidence of an association of ERCC1 and ERCC2 polymorphisms with clinical outcomes of platinum-based chemotherapies in non-small cell lung cancer: A meta-analysis.
Yin M, Yan J, Voutsina A, Tibaldi C, Christiani DC, Heist RS, Rosell R, Booton R, Wei Q
Lung Cancer. 2010
PubMed ID: 21075476
Oxidative damage to biological macromolecules in Prague bus drivers and garagemen: impact of air pollution and genetic polymorphisms.
Bagryantseva Y, Novotna B, Rossner P, Chvatalova I, Milcova A, Svecova V, Lnenickova Z, Solansky I, Sram RJ
Toxicol Lett. 2010
PubMed ID: 20723587
Pharmacogenetic interaction analysis for the efficacy of systemic treatment in metastatic colorectal cancer.
Pander J, Wessels JA, Gelderblom H, van der Straaten T, Punt CJ, Guchelaar HJ
Ann Oncol. 2010
PubMed ID: 21048041
Polymorphisms of nucleotide-excision repair genes may contribute to sperm DNA fragmentation and male infertility.
Gu A, Ji G, Zhou Y, Long Y, Shi X, Fu G, Wang S, Song L, Wang X
Reprod Biomed Online. 2010
PubMed ID: 20864414
The XPD subunit of TFIIH is required for transcription-associated but not DNA double-strand break-induced recombination in mammalian cells.
Savolainen L, Cassel T, Helleday T
Mutagenesis. 2010
PubMed ID: 20833695
Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer.
Palli D, Polidoro S, D'Errico M, Saieva C, Guarrera S, Calcagnile AS, Sera F, Allione A, Gemma S, Zanna I, Filomena A, Testai E, Caini S, Moretti R, Gomez-Miguel MJ, Nesi G, Luzzi I, Ottini L, Masala G, Matullo G, Dogliotti E
Mutagenesis. 2010
PubMed ID: 20817763
Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies.
Shen M, Menashe I, Morton LM, Zhang Y, Armstrong B, Wang SS, Lan Q, Hartge P, Purdue MP, Cerhan JR, Grulich A, Cozen W, Yeager M, Holford TR, Vajdic CM, Davis S, Leaderer B, Kricker A, Severson RK, Zahm SH, Chatterjee N, Rothman N, Chanock SJ, Zheng T
Br J Haematol. 2010
PubMed ID: 20813000
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non-small-cell lung cancer.
Kim M, Kang HG, Lee SY, Lee HC, Lee EB, Choi YY, Lee WK, Cho S, Jin G, Jheon HS, Son JW, Lee MH, Jung DK, Cha SI, Kim CH, Kang YM, Kam S, Jung TH, Jheon S, Park JY
Cancer Sci. 2010
PubMed ID: 20731661
ERCC2 Lys751Gln and Asp312Asn polymorphisms and gastric cancer risk: a meta-analysis.
Chen B, Zhou Y, Yang P, Wu XT
J Cancer Res Clin Oncol. 2010
PubMed ID: 20981556
Polymorphisms of COMT and XPD and risk of esophageal squamous cell carcinoma in a population of Yili Prefecture, in Xinjiang, China.
Huang CG, Iv GD, Liu T, Liu Q, Feng JG, Lu XM
Biomarkers. 2010
PubMed ID: 20979431
Nucleotide excision repair gene polymorphisms may predict acute toxicity in patients treated with chemoradiotherapy for bladder cancer.
Sakano S, Hinoda Y, Sasaki M, Wada T, Matsumoto H, Eguchi S, Shinohara A, Kawai Y, Hara T, Nagao K, Hara T, Naito K, Matsuyama H
Pharmacogenomics. 2010
PubMed ID: 21047201
Influence of genetic polymorphisms on frequency of micronucleated buccal epithelial cells in leukoplakia patients.
Mahimkar MB, Samant TA, Kannan S, Patil T
Oral Oncol. 2010
PubMed ID: 20850372
Association of TGF-β1 and XPD polymorphisms with severe acute radiation-induced esophageal toxicity in locally advanced lung cancer patients treated with radiotherapy.
Zhang L, Yang M, Bi N, Ji W, Wu C, Tan W, Zhao L, Yu D, Lin D, Wang L
Radiother Oncol. 2010
PubMed ID: 20832885
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma.
Figl A, Scherer D, Nagore E, Bermejo JL, Botella-Estrada R, Gast A, Thirumaran RK, Planelles D, Hemminki K, Schadendorf D, Kumar R
Mutat Res. 2010
PubMed ID: 20601096
Association of DNA repair gene XRCC1 and XPD polymorphisms with genetic susceptibility to gastric cancer in a Chinese population.
Yuan T, Deng S, Chen M, Chen W, Lu W, Huang H, Xia J
Cancer Epidemiol. 2010
PubMed ID: 20863780
Effects of selected genetic polymorphisms in xeroderma pigmentosum complementary group D on gastric cancer.
Chen Z, Zhang C, Xu C, Li K, Hou R, Li D, Cheng X
Mol Biol Rep. 2010
PubMed ID: 20842450
ERCC2/XPD Lys751Gln and Asp312Asn gene polymorphism and lung cancer risk: a meta-analysis involving 22 case-control studies.
Zhan P, Wang Q, Wei SZ, Wang J, Qian Q, Yu LK, Song Y
J Thorac Oncol. 2010
PubMed ID: 20651612
ERCC2 Lys751Gln polymorphism is associated with lung cancer among Caucasians.
Zhang J, Gu SY, Zhang P, Jia Z, Chang JH
Eur J Cancer. 2010
PubMed ID: 20627704
MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation.
Ito S, Tan LJ, Andoh D, Narita T, Seki M, Hirano Y, Narita K, Kuraoka I, Hiraoka Y, Tanaka K
Mol Cell. 2010
PubMed ID: 20797633
Phase II study of biweekly S-1 and oxaliplatin combination chemotherapy in metastatic colorectal cancer and pharmacogenetic analysis.
Hong J, Han SW, Ham HS, Kim TY, Choi IS, Kim BS, Oh DY, Im SA, Kang GH, Bang YJ, Kim TY
Cancer Chemother Pharmacol. 2010
PubMed ID: 20734048
Association between Genetic Polymorphisms in the XRCC1, XRCC3, XPD, GSTM1, GSTT1, MSH2, MLH1, MSH3, and MGMT Genes and Radiosensitivity in Breast Cancer Patients.
Mangoni M, Bisanzi S, Carozzi F, Sani C, Biti G, Livi L, Barletta E, Costantini AS, Gorini G
Int J Radiat Oncol Biol Phys. 2010
PubMed ID: 20708344
Oxidative stress, Helicobacter pylori, and OGG1 Ser326Cys, XPC Lys939Gln, and XPD Lys751Gln polymorphisms in a Turkish population with colorectal carcinoma.
Engin AB, Karahalil B, Engin A, Karakaya AE
Genet Test Mol Biomarkers. 2010
PubMed ID: 20649433
Polymorphisms in DNA damage response genes and head and neck cancer risk.
Flores-Obando RE, Gollin SM, Ragin CC
Biomarkers. 2010
PubMed ID: 20429839
The association between ERCC2 Asp312Asn polymorphism and breast cancer risk: a meta-analysis involving 22,766 subjects.
Yao L, Qiu LX, Yu L, Yang Z, Yu XJ, Zhong Y, Hu XC, Yu L
Breast Cancer Res Treat. 2010
PubMed ID: 20127278
Genetic polymorphisms in XRCC1 associated with radiation therapy in prostate cancer.
Gao R, Price DK, Dahut WL, Steinberg SM, Reed E, Figg WD
Cancer Biol Ther. 2010
PubMed ID: 20495366
A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.
Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissière-Michot F, Thezenas S, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E
Pharmacogenomics J. 2010
PubMed ID: 20644561
Variation within DNA repair pathway genes and risk of multiple sclerosis.
Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium
Am J Epidemiol. 2010
PubMed ID: 20522537
Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741.
McLeod HL, Sargent DJ, Marsh S, Green EM, King CR, Fuchs CS, Ramanathan RK, Williamson SK, Findlay BP, Thibodeau SN, Grothey A, Morton RF, Goldberg RM
J Clin Oncol. 2010
PubMed ID: 20530282
XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia.
Guillem VM, Cervantes F, Martínez J, Alvarez-Larrán A, Collado M, Camós M, Sureda A, Maffioli M, Marugán I, Hernández-Boluda JC
Am J Hematol. 2010
PubMed ID: 20575039
Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India.
Srivastava K, Srivastava A, Mittal B
Cancer. 2010
PubMed ID: 20564624
Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk.
Gao W, Romkes M, Zhong S, Nukui T, Persad RA, Smith PJ, Branch R, Keohavong P
Oncol Rep. 2010
PubMed ID: 20514470
A Large-scale genetic association study of esophageal adenocarcinoma risk.
Liu CY, Wu MC, Chen F, Ter-Minassian M, Asomaning K, Zhai R, Wang Z, Su L, Heist RS, Kulke MH, Lin X, Liu G, Christiani DC
Carcinogenesis. 2010
PubMed ID: 20453000
MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck cancer susceptibility: a case control study.
Sliwinski T, Przybylowska K, Markiewicz L, Rusin P, Pietruszewska W, Zelinska-Blizniewska H, Olszewski J, Morawiec-Sztandera A, Mlynarski W, Majsterek I
Mol Biol Rep. 2010
PubMed ID: 20571908
A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.
Anindya R, Mari PO, Kristensen U, Kool H, Giglia-Mari G, Mullenders LH, Fousteri M, Vermeulen W, Egly JM, Svejstrup JQ
Mol Cell. 2010
PubMed ID: 20541997
Single nucleotide polymorphisms in MDR1 gen correlates with outcome in advanced non-small-cell lung cancer patients treated with cisplatin plus vinorelbine.
Viñolas N, Provencio M, Reguart N, Cardenal F, Alberola V, Sánchez-Torres JM, Barón FJ, Cobo M, Maestu I, Moreno I, Mesía C, Izquierdo A, Felip E, López-Brea M, Márquez A, Sánchez-Ronco M, Tarón M, Santarpia MC, Rosell R, on behalf of the Spanish Lung Cancer Group
Lung Cancer. 2010
PubMed ID: 20627363
Insulin-like growth factors II exon 9 and E-cadherin-Pml I but not myeloperoxidase promoter-463, urokinase-ApaL I nor xeroderma pigmentosum polymorphisms are associated with higher susceptibility to leiomyoma.
Hsieh YY, Chang CC, Wang YK, Hsu KH, Chen CP, Hsu CM, Tsai FJ
Anticancer Res. 2010
PubMed ID: 20651370
Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response.
Balboa E, Duran G, Lamas MJ, Gomez-Caamaño A, Celeiro-Muñoz C, Lopez R, Carracedo A, Barros F
Pharmacogenomics. 2010
PubMed ID: 20504250
The value of XPD and XRCC1 genotype polymorphisms to predict clinical outcome in metastatic colorectal carcinoma patients with irinotecan-based regimens.
Artac M, Bozcuk H, Pehlivan S, Akcan S, Pehlivan M, Sever T, Ozdogan M, Savas B
J Cancer Res Clin Oncol. 2010
PubMed ID: 19908066
Nucleotide excision repair polymorphisms and survival outcome for patients with metastatic breast cancer.
Bewick MA, Lafrenie RM, Conlon MS
J Cancer Res Clin Oncol. 2010
PubMed ID: 20508946
Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.
Monsees GM, Kraft P, Chanock SJ, Hunter DJ, Han J
Breast Cancer Res Treat. 2010
PubMed ID: 20496165
Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05.
Boige V, Mendiboure J, Pignon JP, Loriot MA, Castaing M, Barrois M, Malka D, Trégouët DA, Bouché O, Le Corre D, Miran I, Mulot C, Ducreux M, Beaune P, Laurent-Puig P
J Clin Oncol. 2010
PubMed ID: 20385995
[The association of XPD G312A polymorphism with lung cancer risk: a meta-analysis].
Mei C, Deng W, Zhou Q
Zhongguo Fei Ai Za Zhi. 2010
PubMed ID: 20677654
[Genetic polymorphism in XPD related to risks of chronic benzene poisoning].
Li Y, Zhang Z, Sun P, Wan J, Jin X, Xia Z
Wei Sheng Yan Jiu. 2010
PubMed ID: 20568454
Significant association of XPD Asp312Asn polymorphism with breast cancer in Taiwanese patients.
Wang HC, Liu CS, Wang CH, Tsai RY, Tsai CW, Wang RF, Chang CH, Chen YS, Chiu CF, Bau DT, Huang CY
Chin J Physiol. 2010
PubMed ID: 21793320
Meta-analysis of two ERCC2 (XPD) polymorphisms, Asp312Asn and Lys751Gln, in breast cancer.
Pabalan N, Francisco-Pabalan O, Sung L, Jarjanazi H, Ozcelik H
Breast Cancer Res Treat. 2010
PubMed ID: 20379847
Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related macular degeneration.
Görgün E, Güven M, Unal M, Batar B, Güven GS, Yenerel M, Tatlipinar S, Seven M, Yüksel A
Invest Ophthalmol Vis Sci. 2010
PubMed ID: 20375340
Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
Cecchin E, Agostini M, Pucciarelli S, De Paoli A, Canzonieri V, Sigon R, De Mattia E, Friso ML, Biason P, Visentin M, Nitti D, Toffoli G
Pharmacogenomics J. 2010
PubMed ID: 20368715
Possible associations of APE1 polymorphism with susceptibility and HOGG1 polymorphism with prognosis in gastric cancer.
Canbay E, Agachan B, Gulluoglu M, Isbir T, Balik E, Yamaner S, Bulut T, Cacina C, Eraltan IY, Yilmaz A, Bugra D
Anticancer Res. 2010
PubMed ID: 20530453
DNA repair gene X-ray repair cross-complementing group 1 and xeroderma pigmentosum group D polymorphisms and risk of prostate cancer: a study from North India.
Mandal RK, Gangwar R, Mandhani A, Mittal RD
DNA Cell Biol. 2010
PubMed ID: 20070155
The association between XPD Asp312Asn polymorphism and lung cancer risk: a meta-analysis including 16,949 subjects.
Zhang J, Qiu LX, Leaw SJ, Hu XC, Chang JH
Med Oncol. 2010
PubMed ID: 20354818
Association Between Polymorphisms of ERCC1 and XPD and Clinical Response to Platinum-Based Chemotherapy in Advanced Non-Small Cell Lung Cancer.
Li F, Sun X, Sun N, Qin S, Cheng H, Feng J, Chen B, Cheng L, Lu Z, Ji J, Zhou Y
Am J Clin Oncol. 2010
PubMed ID: 20351547
Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): a dose-finding study and pharmacogenomic analysis.
Zarate R, Rodríguez J, Bandres E, Patiño-Garcia A, Ponz-Sarvise M, Viudez A, Ramirez N, Bitarte N, Chopitea A, Gacía-Foncillas J
Br J Cancer. 2010
PubMed ID: 20216541
Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia.
Shi JY, Ren ZH, Jiao B, Xiao R, Yun HY, Chen B, Zhao WL, Zhu Q, Chen Z, Chen SJ
Int J Cancer. 2010
PubMed ID: 20232390
Genetic polymorphisms in DNA repair genes XPC, XPD, and XRCC4, and susceptibility to Helicobacter pylori infection-related gastric antrum adenocarcinoma in Guangxi population, China.
Long XD, Ma Y, Huang YZ, Yi Y, Liang QX, Ma AM, Zeng LP, Fu GH
Mol Carcinog. 2010
PubMed ID: 20232359
Polymorphisms in DNA repair genes XRCC1, XRCC3 and XPD, and colorectal cancer risk: a case-control study in an Indian population.
Wang J, Zhao Y, Jiang J, Gajalakshmi V, Kuriki K, Nakamura S, Akasaka S, Ishikawa H, Suzuki S, Nagaya T, Tokudome S
J Cancer Res Clin Oncol. 2010
PubMed ID: 20229274
XPD Lys751Gln polymorphism and breast cancer susceptibility: a meta-analysis involving 28,709 subjects.
Qiu LX, Yao L, Zhang J, Zhu XD, Zhao XM, Xue K, Mao C, Chen B, Zhan P, Yuan H, Hu XC
Breast Cancer Res Treat. 2010
PubMed ID: 20204500
XPD Polymorphisms and Risk of Squamous Cell Carcinoma of the Head and Neck in a Korean Sample.
Ji YB, Tae K, Lee YS, Lee SH, Kim KR, Park CW, Park BL, Shin HD
Clin Exp Otorhinolaryngol. 2010
PubMed ID: 20379402
Synergistic effects of polymorphisms in DNA repair genes and endogenous estrogen exposure on female breast cancer risk.
Ming-Shiean H, Yu JC, Wang HW, Chen ST, Hsiung CN, Ding SL, Wu PE, Shen CY, Cheng CW
Ann Surg Oncol. 2010
PubMed ID: 20183911
Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6.
Han SW, Oh DY, Im SA, Park SR, Lee KW, Song HS, Lee NS, Lee KH, Choi IS, Lee MH, Kim MA, Kim WH, Bang YJ, Kim TY
Cancer Sci. 2010
PubMed ID: 20047592
Interactions between ultraviolet light exposure and DNA repair gene polymorphisms may increase melanoma risk.
Di Lucca J, Guedj M, Descamps V, Bourillon A, Dieudé P, Saiag P, Wolkenstein P, Dupin N, Lebbe C, Basset-Seguin N, Grandchamp B, Soufir N
Br J Dermatol. 2010
PubMed ID: 20199546
Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity.
Zschenker O, Raabe A, Boeckelmann IK, Borstelmann S, Szymczak S, Wellek S, Rades D, Hoeller U, Ziegler A, Dikomey E, Borgmann K
Radiother Oncol. 2010
PubMed ID: 20170971
ERCC1 haplotypes modify bladder cancer risk: a case-control study.
Ricceri F, Guarrera S, Sacerdote C, Polidoro S, Allione A, Fontana D, Destefanis P, Tizzani A, Casetta G, Cucchiarale G, Vineis P, Matullo G
DNA Repair (Amst). 2010
PubMed ID: 20061190
Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma.
Chen YC, Tzeng CH, Chen PM, Lin JK, Lin TC, Chen WS, Jiang JK, Wang HS, Wang WS
Cancer Sci. 2010
PubMed ID: 19922504
Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.
Agalliu I, Kwon EM, Salinas CA, Koopmeiners JS, Ostrander EA, Stanford JL
Cancer Causes Control. 2010
PubMed ID: 19902366
Modulation of nucleotide excision repair in human lymphocytes by genetic and dietary factors.
Langie SA, Wilms LC, Hämäläinen S, Kleinjans JC, Godschalk RW, van Schooten FJ
Br J Nutr. 2010
PubMed ID: 19878615
Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients.
Khrunin AV, Moisseev A, Gorbunova V, Limborska S
Pharmacogenomics J. 2010
PubMed ID: 19786980
Associations between XPD polymorphisms and risk of breast cancer: a meta-analysis.
Jiang Z, Li C, Xu Y, Cai S, Wang X
Breast Cancer Res Treat. 2010
PubMed ID: 20111903
Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis.
Kiyohara C, Takayama K, Nakanishi Y
J Nucleic Acids. 2010
PubMed ID: 20981350
Interactions between exposure to environmental polycyclic aromatic hydrocarbons and DNA repair gene polymorphisms on bulky DNA adducts in human sperm.
Ji G, Gu A, Zhou Y, Shi X, Xia Y, Long Y, Song L, Wang S, Wang X
PLoS One. 2010
PubMed ID: 20957144
Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population.
Jelonek K, Gdowicz-Klosok A, Pietrowska M, Borkowska M, Korfanty J, Rzeszowska-Wolny J, Widlak P
J Appl Genet. 2010
PubMed ID: 20720310
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PLoS One. 2010
PubMed ID: 20634891
Pterygium and genetic polymorphisms of the DNA repair enzymes XRCC1, XPA, and XPD.
Chiang CC, Tsai YY, Bau DT, Cheng YW, Tseng SH, Wang RF, Tsai FJ
Mol Vis. 2010
PubMed ID: 20431719
[Genetic susceptibility of DNA damage induced by vinyl chloride monomer exposure]
Ji F, Zhu SM, Wang AH, Qu YB, Gu SY, Zhu R, Cai SJ, Li J, Xia ZL
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2010
PubMed ID: 20426969
DNA repair genes in endometriosis.
Attar R, Cacina C, Sozen S, Attar E, Agachan B
Genet Mol Res. 2010
PubMed ID: 20391347
Lifestyle, environmental, and genetic predictors of bulky DNA adducts in a study population nested within a prospective Danish cohort.
Eriksen KT, Sørensen M, Autrup H, Vogel U, Overvad K, Tjønneland A, Loft S, Raaschou-Nielsen O
J Toxicol Environ Health A. 2010
PubMed ID: 20391138
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.
Rajaraman P, Hutchinson A, Wichner S, Black PM, Fine HA, Loeffler JS, Selker RG, Shapiro WR, Rothman N, Linet MS, Inskip PD
Neuro Oncol. 2010
PubMed ID: 20150366
Association of XPD/ERCC2 G23591A and A35931C polymorphisms with skin lesion prevalence in a multiethnic, arseniasis-hyperendemic village exposed to indoor combustion of high arsenic coal.
Lin GF, Du H, Chen JG, Lu HC, Guo WC, Golka K, Shen JH
Arch Toxicol. 2010
PubMed ID: 19834688
Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients.
Ueda T, Compe E, Catez P, Kraemer KH, Egly JM
J Exp Med. 2009
PubMed ID: 19934020
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Dev Cell. 2009
PubMed ID: 20059953
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
Hosgood HD, Zhang L, Shen M, Berndt SI, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan Q
Occup Environ Med. 2009
PubMed ID: 19773279
Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial.
Braun MS, Richman SD, Thompson L, Daly CL, Meade AM, Adlard JW, Allan JM, Parmar MK, Quirke P, Seymour MT
J Clin Oncol. 2009
PubMed ID: 19858398
DNA repair gene polymorphisms and prostate cancer risk in South Australia-results of a pilot study.
Dhillon VS, Yeoh E, Fenech M
Urol Oncol. 2009
PubMed ID: 19914098
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
[Correlation of XPD gene with susceptibility to gastric cancer]
Zhang CZ, Chen ZP, Xu CQ, Ning T, Li DP, Hou RP
Ai Zheng. 2009
PubMed ID: 19895736
[The Association between Polymorphisms of XPD and Susceptibility of Lung Cancer: A meta Analysis.].
Jia Z, Yin Z, Guan P, Zhou B
Zhongguo Fei Ai Za Zhi. 2009
PubMed ID: 20723346
Candidate gene association study of esophageal squamous cell carcinoma in a high-risk region in Iran.
Akbari MR, Malekzadeh R, Shakeri R, Nasrollahzadeh D, Foumani M, Sun Y, Pourshams A, Sadjadi A, Jafari E, Sotoudeh M, Kamangar F, Boffetta P, Dawsey SM, Ghadirian P, Narod SA
Cancer Res. 2009
PubMed ID: 19826048
Significant association of XPD codon 312 single nucleotide polymorphism with bladder cancer susceptibility in Taiwan.
Chang CH, Wang RF, Tsai RY, Wu HC, Wang CH, Tsai CW, Chang CL, Tsou YA, Liu CS, Bau DT
Anticancer Res. 2009
PubMed ID: 19846926
A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.
Young RP, Hopkins RJ, Hay BA, Epton MJ, Mills GD, Black PN, Gardner HD, Sullivan R, Gamble GD
Postgrad Med J. 2009
PubMed ID: 19789190
XRCC1 codon 280 and ERCC2 codon 751 polymorphisms and risk of esophageal squamous cell carcinoma in a Chinese population.
Zhai XD, Mo YN, Xue XQ, Zhao GS, Gao LB, Ai HW, Ye Y
Bull Cancer. 2009
PubMed ID: 19762325
Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma.
Worrillow L, Roman E, Adamson PJ, Kane E, Allan JM, Lightfoot TJ
Cancer Epidemiol. 2009
PubMed ID: 19736055
Proteins and single nucleotide polymorphisms involved in apoptosis, growth control, and DNA repair predict cisplatin sensitivity in head and neck cancer cell lines.
Farnebo L, Jedlinski A, Ansell A, Vainikka L, Thunell LK, Grénman R, Johansson AC, Roberg K
Int J Mol Med. 2009
PubMed ID: 19724896
DNA repair gene polymorphisms and risk of cutaneous melanoma: a systematic review and meta-analysis.
Mocellin S, Verdi D, Nitti D
Carcinogenesis. 2009
PubMed ID: 19706646
Genetic polymorphisms in DNA repair gene APE1, XRCC1 and XPD and the risk of pre-eclampsia.
Vural P, Değirmencioğlu S, Doğru-Abbasoğlu S, Saral NY, Akgül C, Uysal M
Eur J Obstet Gynecol Reprod Biol. 2009
PubMed ID: 19592152
Micronucleus-centromere assay and DNA repair gene polymorphism in lymphocytes of industrial radiographers.
Cho YH, Kim YJ, An YS, Woo HD, Choi SY, Kang CM, Chung HW
Mutat Res. 2009
PubMed ID: 19733688
[Genetic susceptibility of single nucleotide polymorphism in MGMT to non-Hodgkin lymphoma]
Yang F, Shi JY, Xu L, Ren LJ, Zhang QH, Zhao WL, Shen ZX
Zhonghua Xue Ye Xue Za Zhi. 2009
PubMed ID: 19954624
Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.
Stern MC, Lin J, Figueroa JD, Kelsey KT, Kiltie AE, Yuan JM, Matullo G, Fletcher T, Benhamou S, Taylor JA, Placidi D, Zhang ZF, Steineck G, Rothman N, Kogevinas M, Silverman D, Malats N, Chanock S, Wu X, Karagas MR, Andrew AS, Nelson HH, Bishop DT, Sak SC, Choudhury A, Barrett JH, Elliot F, Corral R, Joshi AD, Gago-Dominguez M, Cortessis VK, Xiang YB, Gao YT, Vineis P, Sacerdote C, Guarrera S, Polidoro S, Allione A, Gurzau E, Koppova K, Kumar R, Rudnai P, Porru S, Carta A, Campagna M, Arici C, Park SS, Garcia-Closas M, International Consortium of Bladder Cancer
Cancer Res. 2009
PubMed ID: 19706757
Association between genetic polymorphism in DNA repair genes and risk of B-cell lymphoma.
Baris S, Celkan T, Batar B, Guven M, Ozdil M, Ozkan A, Apak H, Yildiz I
Pediatr Hematol Oncol. 2009
PubMed ID: 19657998
Racial differences in advanced colorectal cancer outcomes and pharmacogenetics: a subgroup analysis of a large randomized clinical trial.
Sanoff HK, Sargent DJ, Green EM, McLeod HL, Goldberg RM
J Clin Oncol. 2009
PubMed ID: 19636001
DNA repair polymorphisms associated with cytogenetic subgroups in B-cell chronic lymphocytic leukemia.
Ganster C, Neesen J, Zehetmayer S, Jäger U, Esterbauer H, Mannhalter C, Kluge B, Fonatsch C
Genes Chromosomes Cancer. 2009
PubMed ID: 19484764
Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity.
Polosak J, Roszkowska-Gancarz M, Kurylowicz A, Owczarz M, Dobosz P, Mossakowska M, Szybinska A, Puzianowska-Kuznicka M
Biogerontology. 2009
PubMed ID: 19707883
Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
Eur Urol. 2009
PubMed ID: 19692168
XPD Lys(751)Gln and Asp (312)Asn polymorphisms and bladder cancer risk: a meta-analysis.
Li C, Jiang Z, Liu X
Mol Biol Rep. 2009
PubMed ID: 19669592
Sequence variant discovery in DNA repair genes from radiosensitive and radiotolerant prostate brachytherapy patients.
Pugh TJ, Keyes M, Barclay L, Delaney A, Krzywinski M, Thomas D, Novik K, Yang C, Agranovich A, McKenzie M, Morris WJ, Olive PL, Marra MA, Moore RA
Clin Cancer Res. 2009
PubMed ID: 19638463
Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes.
Bradbury PA, Kulke MH, Heist RS, Zhou W, Ma C, Xu W, Marshall AL, Zhai R, Hooshmand SM, Asomaning K, Su L, Shepherd FA, Lynch TJ, Wain JC, Christiani DC, Liu G
Pharmacogenet Genomics. 2009
PubMed ID: 19620936
Common genetic variants in candidate genes and risk of familial lymphoid malignancies.
Liang XS, Caporaso N, McMaster ML, Ng D, Landgren O, Yeager M, Chanock S, Goldin LR
Br J Haematol. 2009
PubMed ID: 19573080
The polymorphism of DNA repair gene ERCC2/XPD Arg156Arg and susceptibility to breast cancer in a Chinese population.
Yin J, Liang D, Vogel U, Chang Y, Liu Z, Yue L, Sun X, Qi R, Song T
Biochem Genet. 2009
PubMed ID: 19466538
Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.
Kweekel DM, Antonini NF, Nortier JW, Punt CJ, Gelderblom H, Guchelaar HJ
Br J Cancer. 2009
PubMed ID: 19536092
PTEN identified as important risk factor of chronic obstructive pulmonary disease.
Hosgood HD, Menashe I, He X, Chanock S, Lan Q
Respir Med. 2009
PubMed ID: 19625176
Japanese-US common-arm analysis of paclitaxel plus carboplatin in advanced non-small-cell lung cancer: a model for assessing population-related pharmacogenomics.
Gandara DR, Kawaguchi T, Crowley J, Moon J, Furuse K, Kawahara M, Teramukai S, Ohe Y, Kubota K, Williamson SK, Gautschi O, Lenz HJ, McLeod HL, Lara PN, Coltman CA, Fukuoka M, Saijo N, Fukushima M, Mack PC
J Clin Oncol. 2009
PubMed ID: 19470925
[Study on the relationship between hapatocellular carcinoma and the interaction between polymorphisms in DNA repair gene XPD and environmental factors]
Zeng XY, Qiu XQ, Ji L, Yu HP
Zhonghua Liu Xing Bing Xue Za Zhi. 2009
PubMed ID: 19957595
Common polymorphisms in the XPD and hOGG1 genes are not associated with the risk of colorectal cancer in a Polish population.
Sliwinski T, Krupa R, Wisniewska-Jarosinska M, Pawlowska E, Lech J, Chojnacki J, Blasiak J
Tohoku J Exp Med. 2009
PubMed ID: 19561388
Very low prevalence of XPD K751Q polymorphism and its association with XPD expression and outcomes of FOLFOX-4 treatment in Asian patients with colorectal carcinoma.
Lai JI, Tzeng CH, Chen PM, Lin JK, Lin TC, Chen WS, Jiang JK, Wang HS, Wang WS
Cancer Sci. 2009
PubMed ID: 19432884
HapMap-based study of the DNA repair gene ERCC2 and lung cancer susceptibility in a Chinese population.
Yin J, Vogel U, Ma Y, Qi R, Wang H
Carcinogenesis. 2009
PubMed ID: 19406934
Oral Contraceptives: A Risk Factor for Squamous Cell Carcinoma?
Applebaum KM, Nelson HH, Zens MS, Stukel TA, Spencer SK, Karagas MR
J Invest Dermatol. 2009
PubMed ID: 19554020
Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: a study of the arbeitsgemeinschaft internistische onkologie.
Goekkurt E, Al-Batran SE, Hartmann JT, Mogck U, Schuch G, Kramer M, Jaeger E, Bokemeyer C, Ehninger G, Stoehlmacher J
J Clin Oncol. 2009
PubMed ID: 19332728
Association of XPD polymorphisms with severe toxicity in non-small cell lung cancer patients in a Chinese population.
Wu W, Zhang W, Qiao R, Chen D, Wang H, Wang Y, Zhang S, Gao G, Gu A, Shen J, Qian J, Fan W, Jin L, Han B, Lu D
Clin Cancer Res. 2009
PubMed ID: 19458053
DNA repair genotype interacts with arsenic exposure to increase bladder cancer risk.
Andrew AS, Mason RA, Kelsey KT, Schned AR, Marsit CJ, Nelson HH, Karagas MR
Toxicol Lett. 2009
PubMed ID: 19429237
Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer.
Chang-Claude J, Ambrosone CB, Lilla C, Kropp S, Helmbold I, von Fournier D, Haase W, Sautter-Bihl ML, Wenz F, Schmezer P, Popanda O
Br J Cancer. 2009
PubMed ID: 19367277
Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients.
Caronia D, Patiño-García A, Milne RL, Zalacain-Díez M, Pita G, Alonso MR, Moreno LT, Sierrasesumaga-Ariznabarreta L, Benítez J, González-Neira A
Pharmacogenomics J. 2009
PubMed ID: 19434073
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Gene-environment interactions between DNA repair polymorphisms and exposure to the carcinogen vinyl chloride.
Li Y, Marion MJ, Zipprich J, Santella RM, Freyer G, Brandt-Rauf PW
Biomarkers. 2009
PubMed ID: 19274602
Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.
Pan J, Lin J, Izzo JG, Liu Y, Xing J, Huang M, Ajani JA, Wu X
Carcinogenesis. 2009
PubMed ID: 19270000
Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.
Michiels S, Laplanche A, Boulet T, Dessen P, Guillonneau B, Méjean A, Desgrandchamps F, Lathrop M, Sarasin A, Benhamou S
Carcinogenesis. 2009
PubMed ID: 19237606
Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: a Korean population-based study.
Kim HS, Kim MK, Chung HH, Kim JW, Park NH, Song YS, Kang SB
Gynecol Oncol. 2009
PubMed ID: 19203783
Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
Environ Mol Mutagen. 2009
PubMed ID: 19170196
Genetic polymorphisms in DNA repair genes as modulators of Hodgkin disease risk.
El-Zein R, Monroy CM, Etzel CJ, Cortes AC, Xing Y, Collier AL, Strom SS
Cancer. 2009
PubMed ID: 19280628
Bladder cancer and polymorphisms of DNA repair genes (XRCC1, XRCC3, XPD, XPG, APE1, hOGG1).
Narter KF, Ergen A, Agaçhan B, Görmüs U, Timirci O, Isbir T
Anticancer Res. 2009
PubMed ID: 19414392
[DNA repair gene xeroderma pigmentosum group D 751 polymorphism and the risk on esophageal cancer: a meta-analysis]
Wu XB, Dai LP, Wang YP, Wang KJ, Zhang JY
Zhonghua Liu Xing Bing Xue Za Zhi. 2009
PubMed ID: 19642387
DNA repair gene polymorphisms predict favorable clinical outcome in advanced non-small-cell lung cancer.
Kalikaki A, Kanaki M, Vassalou H, Souglakos J, Voutsina A, Georgoulias V, Mavroudis D
Clin Lung Cancer. 2009
PubMed ID: 19362955
An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.
Andressoo JO, Weeda G, de Wit J, Mitchell JR, Beems RB, van Steeg H, van der Horst GT, Hoeijmakers JH
Mol Cell Biol. 2009
PubMed ID: 19114557
Pharmacogenetic analyses of hematotoxicity in advanced gastric cancer patients receiving biweekly fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).
Goekkurt E, Al-Batran SE, Mogck U, Pauligk C, Hartmann JT, Kramer M, Jaeger E, Ehninger G, Stoehlmacher J
Ann Oncol. 2009
PubMed ID: 19074750
Influence of XPD and APE1 DNA repair gene polymorphism on bladder cancer susceptibility in north India.
Gangwar R, Ahirwar D, Mandhani A, Mittal RD
Urology. 2009
PubMed ID: 19041121
Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Joshi AD, Corral R, Siegmund KD, Haile RW, Le Marchand L, Martínez ME, Ahnen DJ, Sandler RS, Lance P, Stern MC
Carcinogenesis. 2009
PubMed ID: 19029193
Stratification for smoking in case-cohort studies of genetic polymorphisms and lung cancer.
Sørensen M, López AG, Andersen PK, Vogel U, Autrup H, Tjønneland A, Overvad K, Raaschou-Nielsen O
Lung Cancer. 2009
PubMed ID: 18778871
Impact of nucleotide excision repair ERCC2 and base excision repair APEX1 genes polymorphism and its association with recurrence after adjuvant BCG immunotherapy in bladder cancer patients of North India.
Gangawar R, Ahirwar D, Mandhani A, Mittal RD
Med Oncol. 2009
PubMed ID: 19242824
MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity.
Liu L, Ishihara K, Ichimura T, Fujita N, Hino S, Tomita S, Watanabe S, Saitoh N, Ito T, Nakao M
J Biol Chem. 2009
PubMed ID: 19106100
Micronuclei and chromosomal aberrations, important markers of ageing: Possible association with XPC and XPD polymorphisms.
Kazimírová A, Barancoková M, Dzupinková Z, Wsólová L, Dusinská M
Mutat Res. 2009
PubMed ID: 19027756
Analysis of ERCC2/XPD functional polymorphisms in systemic lupus erythematosus.
Wan L, Lin YJ, Sheu JJ, Huang CM, Tsai Y, Tsai CH, Wong W, Tsai FJ
Int J Immunogenet. 2009
PubMed ID: 19055600
Chromosomal aberrations in railroad transit workers: Effect of genetic polymorphisms.
Catalán J, Heilimo I, Falck GC, Järventaus H, Rosenström P, Nykyri E, Kallas-Tarpila T, Pitkämäki L, Hirvonen A, Norppa H
Environ Mol Mutagen. 2009
PubMed ID: 19177501
Polymorphisms of xenobiotic metabolizing enzymes and DNA repair genes and outcome in childhood acute lymphoblastic leukemia.
Silveira VD, Canalle R, Scrideli CA, Queiroz RG, Bettiol H, Valera ET, Tone LG
Leuk Res. 2009
PubMed ID: 19162321
A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility.
Vineis P, Manuguerra M, Kavvoura FK, Guarrera S, Allione A, Rosa F, Di Gregorio A, Polidoro S, Saletta F, Ioannidis JP, Matullo G
J Natl Cancer Inst. 2009
PubMed ID: 19116388
Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study.
Stern MC, Butler LM, Corral R, Joshi AD, Yuan JM, Koh WP, Yu MC
J Nutrigenet Nutrigenomics. 2009
PubMed ID: 20559012
Lack of influence of XRCC1 and XPD gene polymorphisms on outcome of platinum-based chemotherapy for advanced non small cell lung cancers.
Yao CY, Huang XE, Li C, Shen HB, Shi MQ, Feng JF, Pan LX, Tang JH
Asian Pac J Cancer Prev. 2009
PubMed ID: 20104979
Association between polymorphisms in DNA repair genes and survival of non-smoking female patients with lung adenocarcinoma.
Yin Z, Zhou B, He Q, Li M, Guan P, Li X, Cui Z, Xue X, Su M, Ma R, Bai W, Xia S, Jiang Y, Xu S, Lv Y, Li X
BMC Cancer. 2009
PubMed ID: 20003463
ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females.
Yin Z, Su M, Li X, Li M, Ma R, He Q, Zhou B
J Exp Clin Cancer Res. 2009
PubMed ID: 20003391
XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk.
Long XD, Ma Y, Zhou YF, Yao JG, Ban FZ, Huang YZ, Huang BC
BMC Cancer. 2009
PubMed ID: 19919686
Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population.
Mitra AK, Singh N, Garg VK, Chaturvedi R, Sharma M, Rath SK
J Exp Clin Cancer Res. 2009
PubMed ID: 19615095
XPD polymorphisms, cigarette smoking, and bladder cancer risk: a meta-analysis.
Wang M, Gu D, Zhang Z, Zhou J, Zhang Z
J Toxicol Environ Health A. 2009
PubMed ID: 19492231
In vitro nuclear interactome of the HIV-1 Tat protein.
Gautier VW, Gu L, O'Donoghue N, Pennington S, Sheehy N, Hall WW
Retrovirology. 2009
PubMed ID: 19454010
Lung cancer susceptibility model based on age, family history and genetic variants.
Young RP, Hopkins RJ, Hay BA, Epton MJ, Mills GD, Black PN, Gardner HD, Sullivan R, Gamble GD
PLoS One. 2009
PubMed ID: 19390575
Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups.
Schierup MH, Mailund T, Li H, Wang J, Tjønneland A, Vogel U, Bolund L, Nexø BA
BMC Med Genet. 2009
PubMed ID: 19257887
DNA repair gene variants associated with benign breast disease in high cancer risk women.
Jorgensen TJ, Helzlsouer KJ, Clipp SC, Bolton JH, Crum RM, Visvanathan K
Cancer Epidemiol Biomarkers Prev. 2009
PubMed ID: 19124519
Polymorphisms of DNA repair genes: ADPRT, XRCC1, and XPD and cancer risk in genetic epidemiology.
Jiang J, Zhang X, Yang H, Wang W
Methods Mol Biol. 2009
PubMed ID: 19109787
Strict sun protection results in minimal skin changes in a patient with xeroderma pigmentosum and a novel c.2009delG mutation in XPD (ERCC2).
Emmert S, Ueda T, Zumsteg U, Weber P, Khan SG, Oh KS, Boyle J, Laspe P, Zachmann K, Boeckmann L, Kuschal C, Bircher A, Kraemer KH
Exp Dermatol. 2009
PubMed ID: 18637129
DNA repair gene XPD and XRCC1 polymorphisms and the risk of childhood acute lymphoblastic leukemia.
Batar B, Güven M, Barış S, Celkan T, Yıldız I
Leuk Res. 2008
PubMed ID: 19101034
Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.
Enjuanes A, Benavente Y, Bosch F, Martín-Guerrero I, Colomer D, Pérez-Alvarez S, Reina O, Ardanaz MT, Jares P, García-Orad A, Pujana MA, Montserrat E, de Sanjosé S, Campo E
Cancer Res. 2008
PubMed ID: 19074885
Association between DNA damage, DNA repair genes variability and clinical characteristics in breast cancer patients.
Synowiec E, Stefanska J, Morawiec Z, Blasiak J, Wozniak K
Mutat Res. 2008
PubMed ID: 18977234
Contribution of XPD (Lys751Gln) and XRCC1 (Arg399Gln) Polymorphisms in Familial and Sporadic Breast Cancer Predisposition and Survival: An Indian Report.
Syamala VS, Syamala V, Sreedharan H, Raveendran PB, Kuttan R, Ankathil R
Pathol Oncol Res. 2008
PubMed ID: 19051060
Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.
Palmieri RT, Wilson MA, Iversen ES, Clyde MA, Calingaert B, Moorman PG, Poole C, Anderson AR, Anderson S, Anton-Culver H, Beesley J, Hogdall E, Brewster W, Carney ME, Chen X, Chenevix-Trench G, Chang-Claude J, Cunningham JM, Dicioccio RA, Doherty JA, Easton DF, Edlund CK, Gayther SA, Gentry-Maharaj A, Goode EL, Goodman MT, Kjaer SK, Hogdall CK, Hopkins MP, Jenison EL, Blaakaer J, Lurie G, McGuire V, Menon U, Moysich KB, Ness RB, Pearce CL, Pharoah PD, Pike MC, Ramus SJ, Rossing MA, Song H, Terada KY, Vandenberg D, Vierkant RA, Wang-Gohrke S, Webb PM, Whittemore AS, Wu AH, Ziogas A, Berchuck A, Schildkraut JM, Ovarian Cancer Association Consortium, Australian Cancer Study (Ovarian Cancer Group), Australian Ovarian Cancer Study Group
Cancer Epidemiol Biomarkers Prev. 2008
PubMed ID: 19064572
Case-only study of interactions between DNA repair genes (hMLH1, APEX1, MGMT, XRCC1 and XPD) and low-frequency electromagnetic fields in childhood acute leukemia.
Yang Y, Jin X, Yan C, Tian Y, Tang J, Shen X
Leuk Lymphoma. 2008
PubMed ID: 19052983
Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients.
Nishiwaki T, Kobayashi N, Iwamoto T, Yamamoto A, Sugiura S, Liu YC, Sarasin A, Okahashi Y, Hirano M, Ueno S, Mori T
DNA Repair (Amst). 2008
PubMed ID: 18817897
Polymorphisms of detoxification and DNA repair enzymes in myelodyplastic syndromes.
Fabiani E, D'Alò F, Scardocci A, Greco M, Di Ruscio A, Criscuolo M, Fianchi L, Pagano L, Hohaus S, Leone G, Voso MT
Leuk Res. 2008
PubMed ID: 19027952
International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.
Hung RJ, Christiani DC, Risch A, Popanda O, Haugen A, Zienolddiny S, Benhamou S, Bouchardy C, Lan Q, Spitz MR, Wichmann HE, LeMarchand L, Vineis P, Matullo G, Kiyohara C, Zhang ZF, Pezeshki B, Harris C, Mechanic L, Seow A, Ng DP, Szeszenia-Dabrowska N, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Mates D, Foretova L, Janout V, Bencko V, Caporaso N, Chen C, Duell EJ, Goodman G, Field JK, Houlston RS, Hong YC, Landi MT, Lazarus P, Muscat J, McLaughlin J, Schwartz AG, Shen H, Stucker I, Tajima K, Matsuo K, Thun M, Yang P, Wiencke J, Andrew AS, Monnier S, Boffetta P, Brennan P
Cancer Epidemiol Biomarkers Prev. 2008
PubMed ID: 18990748
Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.
Wu X, Lu C, Ye Y, Chang J, Yang H, Lin J, Gu J, Hong WK, Stewart D, Spitz MR
Pharmacogenet Genomics. 2008
PubMed ID: 18854777
Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans.
Chang JS, Wrensch MR, Hansen HM, Sison JD, Aldrich MC, Quesenberry CP, Seldin MF, Kelsey KT, Kittles RA, Silva G, Wiencke JK
Int J Cancer. 2008
PubMed ID: 18709642
Implications of XRCC1, XPD and APE1 gene polymorphism in North Indian population: a comparative approach in different ethnic groups worldwide.
Gangwar R, Manchanda PK, Mittal RD
Genetica. 2008
PubMed ID: 18946634
Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype.
Tyson J, Caple F, Spiers A, Burtle B, Daly AK, Williams EA, Hesketh JE, Mathers JC
Br J Nutr. 2008
PubMed ID: 18838045
Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy.
Paré L, Marcuello E, Altés A, del Río E, Sedano L, Salazar J, Cortés A, Barnadas A, Baiget M
Br J Cancer. 2008
PubMed ID: 18797464
Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma.
Wang SS, Maurer MJ, Morton LM, Habermann TM, Davis S, Cozen W, Lynch CF, Severson RK, Rothman N, Chanock SJ, Hartge P, Cerhan JR
Leukemia. 2008
PubMed ID: 18830263
Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
Hosgood HD, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q
Carcinogenesis. 2008
PubMed ID: 18676680
Persistence of repair proteins at unrepaired DNA damage distinguishes diseases with ERCC2 (XPD) mutations: cancer-prone xeroderma pigmentosum vs. non-cancer-prone trichothiodystrophy.
Boyle J, Ueda T, Oh KS, Imoto K, Tamura D, Jagdeo J, Khan SG, Nadem C, Digiovanna JJ, Kraemer KH
Hum Mutat. 2008
PubMed ID: 18470933
Nucleotide excision repair polymorphisms may modify ionizing radiation-related breast cancer risk in US radiologic technologists.
Rajaraman P, Bhatti P, Doody MM, Simon SL, Weinstock RM, Linet MS, Rosenstein M, Stovall M, Alexander BH, Preston DL, Sigurdson AJ
Int J Cancer. 2008
PubMed ID: 18767034
Protein expression levels of excision repair cross-complementation group 1 and xeroderma pigmentosum D correlate with response to platinum-based chemotherapy in the patients with advanced epithelial ovarian cancer.
Lin K, Ye D, Xie X
Int J Gynecol Cancer. 2008
PubMed ID: 18081788
Case-Control Analysis of Nucleotide Excision Repair Pathway and the Risk of Renal Cell Carcinoma.
Lin J, Pu X, Wang W, Matin S, Tannir NM, Wood CG, Wu X
Carcinogenesis. 2008
PubMed ID: 18711149
Polygenic Model of DNA-Repair Genetic Polymorphisms in Human Breast Cancer Risk.
Smith TR, Levine EA, Freimanis RI, Akman SA, Allen GO, Hoang KN, Liu-Mares W, Hu JJ
Carcinogenesis. 2008
PubMed ID: 18701435
Polymorphisms in metabolic GSTP1 and DNA-repair XRCC1 genes with an increased risk of DNA damage in pesticide-exposed fruit growers.
Wong RH, Chang SY, Ho SW, Huang PL, Liu YJ, Chen YC, Yeh YH, Lee HS
Mutat Res. 2008
PubMed ID: 18603015
DNA repair polymorphisms and the risk of stomach adenocarcinoma and severe chronic gastritis in the EPIC-EURGAST study.
Capellá G, Pera G, Sala N, Agudo A, Rico F, Del Giudicce G, Plebani M, Palli D, Boeing H, Bueno-de-Mesquita HB, Carneiro F, Berrino F, Vineis P, Tumino R, Panico S, Berglund G, Simán H, Nyrén O, Hallmans G, Martinez C, Dorronsoro M, Barricarte A, Navarro C, Quirós JR, Allen N, Key T, Bingham S, Caldas C, Linseisen J, Nagel G, Overvad K, Tjonneland A, Boshuizen HC, Peeters PH, Numans ME, Clavel-Chapelon F, Trichopoulou A, Lund E, Jenab M, Kaaks R, Riboli E, González CA
Int J Epidemiol. 2008
PubMed ID: 18641418
Genotypes and haplotypes of ERCC1 and ERCC2/XPD genes predict levels of benzo[a]pyrene diol epoxide-induced DNA adducts in cultured primary lymphocytes from healthy individuals: a genotype-phenotype correlation analysis.
Zhao H, Wang LE, Li D, Chamberlain RM, Sturgis EM, Wei Q
Carcinogenesis. 2008
PubMed ID: 18635523
Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay.
Ryk C, Routledge MN, Allan JM, Wild CP, Kumar R, Lambert B, Hou S
Environ Mol Mutagen. 2008
PubMed ID: 18627000
[The evaluation of association between polymorphisms of DNA excision repair enzyme genes and risk of malignant tumors development in Siberian Group of Chemical Enterprises workers]

Radiats Biol Radioecol. 2008
PubMed ID: 18825991
ERCC1 and ERCC2 polymorphisms and risk of idiopathic azoospermia in a Chinese population.
Ji G, Gu A, Xia Y, Lu C, Liang J, Wang S, Ma J, Peng Y, Wang X
Reprod Biomed Online. 2008
PubMed ID: 18616887
The Gln/Gln genotype of XPD codon 751 as a genetic marker for melanoma risk and Lys/Gln as an important predictor for melanoma progression: a case control study in the Swedish population.
Kertat K, Rosdahl I, Sun XF, Synnerstad I, Zhang H
Oncol Rep. 2008
PubMed ID: 18575735
Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma.
Doecke J, Zhao ZZ, Pandeya N, Sadeghi S, Stark M, Green AC, Hayward NK, Webb PM, Whiteman DC, Australian Cancer Study
Int J Cancer. 2008
PubMed ID: 18386788
Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD.
Wolski SC, Kuper J, Hänzelmann P, Truglio JJ, Croteau DL, Van Houten B, Kisker C
PLoS Biol. 2008
PubMed ID: 18578568
Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk.
McWilliams RR, Bamlet WR, Cunningham JM, Goode EL, de Andrade M, Boardman LA, Petersen GM
Cancer Res. 2008
PubMed ID: 18544627
Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer.
Duell EJ, Bracci PM, Moore JH, Burk RD, Kelsey KT, Holly EA
Cancer Epidemiol Biomarkers Prev. 2008
PubMed ID: 18559563
Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
Braun MS, Richman SD, Quirke P, Daly C, Adlard JW, Elliott F, Barrett JH, Selby P, Meade AM, Stephens RJ, Parmar MK, Seymour MT
J Clin Oncol. 2008
PubMed ID: 18509181
mRNA expression of RRM1, ERCC1 and ERCC2 is not associated with chemosensitivity to cisplatin, carboplatin and gemcitabine in human lung cancer cell lines.
Shimizu J, Horio Y, Osada H, Hida T, Hasegawa Y, Shimokata K, Takahashi T, Sekido Y, Yatabe Y
Respirology. 2008
PubMed ID: 18494946
Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer.
Martinez-Balibrea E, Abad A, Aranda E, Sastre J, Manzano JL, Díaz-Rubio E, Gómez-España A, Aparicio J, García T, Maestu I, Martínez-Cardús A, Ginés A, Guino E, on behalf of the Spanish Group for the Treatment of Digestive Tumours (TTD group)
Eur J Cancer. 2008
PubMed ID: 18448328
Prognostic importance of DNA repair gene polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln in lung cancer patients from India.
Sreeja L, Syamala VS, Syamala V, Hariharan S, Raveendran PB, Vijayalekshmi RV, Madhavan J, Ankathil R
J Cancer Res Clin Oncol. 2008
PubMed ID: 17952468
Cytogenetic effects induced by Prestige oil on human populations: The role of polymorphisms in genes involved in metabolism and DNA repair.
Pérez-Cadahía B, Laffon B, Valdiglesias V, Pásaro E, Méndez J
Mutat Res. 2008
PubMed ID: 18495522
Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker.
Keam B, Im SA, Han SW, Ham HS, Kim MA, Oh DY, Lee SH, Kim JH, Kim DW, Kim TY, Heo DS, Kim WH, Bang YJ
BMC Cancer. 2008
PubMed ID: 18505590
Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk.
Tse D, Zhai R, Zhou W, Heist RS, Asomaning K, Su L, Lynch TJ, Wain JC, Christiani DC, Liu G
Cancer Causes Control. 2008
PubMed ID: 18478337
Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes.
Musak L, Soucek P, Vodickova L, Naccarati A, Halasova E, Polakova V, Slyskova J, Susova S, Buchancova J, Smerhovsky Z, Sedikova J, Klimentova G, Osina O, Hemminki K, Vodicka P
Mutat Res. 2008
PubMed ID: 18394656
Haplotypes of nine single nucleotide polymorphisms on chromosome 19q13.2-3 associated with susceptibility of lung cancer in a Chinese population.
Yin J, Vogel U, Ma Y, Qi R, Wang H
Mutat Res. 2008
PubMed ID: 18358500
Polymorphisms and haplotypes of DNA repair and xenobiotic metabolism genes and risk of DNA damage in Chinese vinyl chloride monomer (VCM)-exposed workers.
Zhu SM, Xia ZL, Wang AH, Ren XF, Jiao J, Zhao NQ, Qian J, Jin L, Christiani DC
Toxicol Lett. 2008
PubMed ID: 18420361
DNA repair gene ERCC2, XPC, XRCC1, XRCC3 polymorphisms and associations with bladder cancer risk in a French cohort.
Fontana L, Bosviel R, Delort L, Guy L, Chalabi N, Kwiatkowski F, Satih S, Rabiau N, Boiteux JP, Chamoux A, Bignon YJ, Bernard-Gallon DJ
Anticancer Res. 2008
PubMed ID: 18630471
Genetic polymorphisms in the DNA repair enzyme ERCC2 and breast tumour risk in a Chinese population.
Li J, Jin W, Chen Y, Di G, Wu J, Shao ZM
J Int Med Res. 2008
PubMed ID: 18534129
Ethnic disparities in Americans of European descent versus Americans of African descent related to polymorphic ERCC1, ERCC2, XRCC1, and PARP1.
Gao R, Price DK, Sissung T, Reed E, Figg WD
Mol Cancer Ther. 2008
PubMed ID: 18483312
Polymorphisms in XPC and ERCC2 genes, smoking and breast cancer risk.
Shore RE, Zeleniuch-Jacquotte A, Currie D, Mohrenweiser H, Afanasyeva Y, Koenig KL, Arslan AA, Toniolo P, Wirgin I
Int J Cancer. 2008
PubMed ID: 18196582
Polymorphisms of the XRCC1 and XPD Genes and Breast Cancer Risk: A Case-Control Study.
Kipikašová L, Wolaschka T, Bohuš P, Baumohlová H, Bober J, Blažejová J, Mirossay L, Sarišský M, Miroššay A, Cižmáriková M, Potočeková D, Mojžiš J
Pathol Oncol Res. 2008
PubMed ID: 18415712
Genetic contribution to all cancers: the first demonstration using the model of breast cancers from Poland stratified by age at diagnosis and tumour pathology.
Lubiński J, Korzeń M, Górski B, Cybulski C, Dębniak T, Jakubowska A, Jaworska K, Wokołorczyk D, Mędrek K, Matyjasik J, Huzarski T, Byrski T, Gronwald J, Masojć B, Lener M, Szymańska A, Szymańska-Pasternak J, Serrano-Fernàndez P, Piegat A, Uciński R, Domagała P, Domagała W, Chosia M, Kładny J, Górecka B, Narod S, Scott R
Breast Cancer Res Treat. 2008
PubMed ID: 18415014
Bladder cancer, GSTs, NAT1, NAT2, SULT1A1, XRCC1, XRCC3, XPD genetic polymorphisms and coffee consumption: a case-control study.
Covolo L, Placidi D, Gelatti U, Carta A, Scotto Di Carlo A, Lodetti P, Piccichè A, Orizio G, Campagna M, Arici C, Porru S
Eur J Epidemiol. 2008
PubMed ID: 18365755
Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.
Tibaldi C, Giovannetti E, Vasile E, Mey V, Laan AC, Nannizzi S, Di Marsico R, Antonuzzo A, Orlandini C, Ricciardi S, Del Tacca M, Peters GJ, Falcone A, Danesi R
Clin Cancer Res. 2008
PubMed ID: 18347182
Cisplatin plus weekly CPT-11/docetaxel in advanced esophagogastric cancer: a phase I study with pharmacogenetic assessment of XPD, XRCC3 and UGT1A1 polymorphisms.
Font A, Salazar R, Maurel J, Taron M, Ramirez JL, Tabernero J, Gallego R, Casado E, Manzano JL, Carcereny E, Guix M, Fernández-Llamazares J, Rosell R
Cancer Chemother Pharmacol. 2008
PubMed ID: 18335219
No association between hOGG1, XRCC1, and XPD polymorphisms and risk of reflux esophagitis, Barrett's esophagus, or esophageal adenocarcinoma: results from the factors influencing the Barrett's adenocarcinoma relationship case-control study.
Ferguson HR, Wild CP, Anderson LA, Murphy SJ, Johnston BT, Murray LJ, Watson RG, McGuigan J, Reynolds JV, Hardie LJ
Cancer Epidemiol Biomarkers Prev. 2008
PubMed ID: 18349297
DNA repair gene XPD polymorphisms and cancer risk: a meta-analysis based on 56 case-control studies.
Wang F, Chang D, Hu FL, Sui H, Han B, Li DD, Zhao YS
Cancer Epidemiol Biomarkers Prev. 2008
PubMed ID: 18349268
DNA repair gene polymorphisms may be associated with prognosis of upper urinary tract transitional cell carcinoma.
Sasaki M, Sakano S, Okayama N, Akao J, Hara T, Kawai Y, Ohmi C, Hinoda Y, Naito K
Neoplasia. 2008
PubMed ID: 18320070
[Association of gene polymorphisms in the DNA repair gene XPD with risk of non-Hodgkin's lymphoma]
Song B, Zhu JY, Liu J, Wang ZH, Shi Y, Lü LY, Zheng Y
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008
PubMed ID: 18315909
Influence of GSTM1 null and low repair XPC PAT+ on anti-B[a]PDE-DNA adduct in mononuclear white blood cells of subjects low exposed to PAHs through smoking and diet.
Pavanello S, Pulliero A, Clonfero E
Mutat Res. 2008
PubMed ID: 18035379
Inherited susceptibility to bleomycin-induced micronuclei: correlating polymorphisms in GSTT1, GSTM1 and DNA repair genes with mutagen sensitivity.
Angelini S, Kumar R, Carbone F, Bermejo JL, Maffei F, Cantelli-Forti G, Hemminki K, Hrelia P
Mutat Res. 2008
PubMed ID: 17953974
Polymorphisms in nucleotide excision repair genes, smoking and intake of fruit and vegetables in relation to lung cancer.
Raaschou-Nielsen O, Sørensen M, Overvad K, Tjønneland A, Vogel U
Lung Cancer. 2008
PubMed ID: 17913280
PAH-DNA adducts in a Chinese population: relationship to PAH exposure, smoking and polymorphisms of metabolic and DNA repair genes.
Hu Y, Li G, Xue X, Zhou Z, Li X, Fu J, Cohen B, Roy N, Li D, Sun J, Nan P, Tang MS, Qu Q
Biomarkers. 2008
PubMed ID: 17896209
X-ray repair cross-complementing group 4 (XRCC4) promoter -1394( *)T-related genotype, but not XRCC4 codon 247/intron 3 or xeroderma pigmentosum group D codon 312, 751/promoter -114, polymorphisms are correlated with higher susceptibility to myoma.
Hsieh YY, Chang CC, Bau DT, Yeh LS, Tsai FJ, Tsai CH
Fertil Steril. 2008
PubMed ID: 18177646
Susceptibility of XRCC3, XPD, and XPG genetic variants to cervical carcinoma.
He X, Ye F, Zhang J, Cheng Q, Shen J, Chen H
Pathobiology. 2008
PubMed ID: 19096231
The investigation of DNA repair polymorphisms with histopathological characteristics and hormone receptors in a group of Brazilian women with breast cancer.
Dufloth RM, Arruda A, Heinrich JK, Schmitt F, Zeferino LC
Genet Mol Res. 2008
PubMed ID: 18752184
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.
Skibola CF, Bracci PM, Halperin E, Nieters A, Hubbard A, Paynter RA, Skibola DR, Agana L, Becker N, Tressler P, Forrest MS, Sankararaman S, Conde L, Holly EA, Smith MT
PLoS ONE. 2008
PubMed ID: 18636124
Head and neck squamous-cell cancer and its association with polymorphic enzymes of xenobiotic metabolism and repair.
Harth V, Schafer M, Abel J, Maintz L, Neuhaus T, Besuden M, Primke R, Wilkesmann A, Thier R, Vetter H, Ko YD, Bruning T, Bolt HM, Ickstadt K
J Toxicol Environ Health A. 2008
PubMed ID: 18569591
Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice.
Park JY, Cho MO, Leonard S, Calder B, Mian IS, Kim WH, Wijnhoven S, van Steeg H, Mitchell J, van der Horst GT, Hoeijmakers J, Cohen P, Vijg J, Suh Y
PLoS ONE. 2008
PubMed ID: 18545656
DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk.
Bernard-Gallon D, Bosviel R, Delort L, Fontana L, Chamoux A, Rabiau N, Kwiatkowski F, Chalabi N, Satih S, Bignon YJ
Mol Cancer. 2008
PubMed ID: 18454848
ERCC2 2251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: a preliminary study.
Huang MY, Fang WY, Lee SC, Cheng TL, Wang JY, Lin SR
BMC Cancer. 2008
PubMed ID: 18267032
DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy.
Andrew AS, Karagas MR, Nelson HH, Guarrera S, Polidoro S, Gamberini S, Sacerdote C, Moore JH, Kelsey KT, Demidenko E, Vineis P, Matullo G
Hum Hered. 2008
PubMed ID: 17898541
Relationship between polymorphisms of nucleotide excision repair genes and oral cancer risk in Taiwan: evidence for modification of smoking habit.
Bau DT, Tsai MH, Huang CY, Lee CC, Tseng HC, Lo YL, Tsai Y, Tsai FJ
Chin J Physiol. 2007
PubMed ID: 18442012
Early-onset of sporadic basal-cell carcinoma: germline mutations in the TP53, PTCH, and XPD genes.
Suárez-Martínez EB, Ruiz A, Matías J, Morales L, Cruz A, Vázquez D, Villa J, Matta JL
P R Health Sci J. 2007
PubMed ID: 18246963
[Association of genetic polymorphism of XPD with chromosomal damage in workers exposed to radiation]
Fan XY, Jin YL, Yao SQ, Bai YP, Wu XM, Ren DW, Pen J
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007
PubMed ID: 18230301
Determination of ERCC2 Lys751Gln and GSTP1 Ile105Val gene polymorphisms in colorectal cancer patients: relationships with treatment outcome.
Le Morvan V, Smith D, Laurand A, Brouste V, Bellott R, Soubeyran I, Mathoulin-Pelissier S, Robert J
Pharmacogenomics. 2007
PubMed ID: 18085999
Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression.
Wolfe KJ, Wickliffe JK, Hill CE, Paolini M, Ammenheuser MM, Abdel-Rahman SZ
Pharmacogenet Genomics. 2007
PubMed ID: 18075460
DNA repair gene XRCC1 and XPD polymorphisms and their association with coronary artery disease risks and micronucleus frequency.
Guven M, Guven GS, Oz E, Ozaydin A, Batar B, Ulutin T, Hacihanefioglu S, Domanic N
Heart Vessels. 2007
PubMed ID: 18043991
DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study.
Stern MC, Conti DV, Siegmund KD, Corral R, Yuan JM, Koh WP, Yu MC
Cancer Epidemiol Biomarkers Prev. 2007
PubMed ID: 18006925
Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH.
Compe E, Malerba M, Soler L, Marescaux J, Borrelli E, Egly JM
Nat Neurosci. 2007
PubMed ID: 17952069
DNA repair gene XRCC1 and XPD polymorphisms and the risk of idiopathic azoospermia in a Chinese population.
Gu A, Ji G, Liang J, Xia Y, Lu N, Wu B, Wang W, Song L, Wang S, Wang X
Int J Mol Med. 2007
PubMed ID: 17912469
The association of DNA repair gene polymorphisms with the development and progression of renal cell carcinoma.
Sakano S, Hinoda Y, Okayama N, Kawai Y, Korenaga Y, Eguchi S, Nagao K, Ohmi C, Naito K
Ann Oncol. 2007
PubMed ID: 17712032
Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer.
Marsh S, Paul J, King CR, Gifford G, McLeod HL, Brown R
J Clin Oncol. 2007
PubMed ID: 17925548
Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk.
Crew KD, Gammon MD, Terry MB, Zhang FF, Zablotska LB, Agrawal M, Shen J, Long CM, Eng SM, Sagiv SK, Teitelbaum SL, Neugut AI, Santella RM
Cancer Epidemiol Biomarkers Prev. 2007
PubMed ID: 17932351
Moving toward individualized therapy based on NER polymorphisms that predict platinum sensitivity in ovarian cancer patients.
Saldivar JS, Lu KH, Liang D, Gu J, Huang M, Vlastos AT, Follen M, Wu X
Gynecol Oncol. 2007
PubMed ID: 17825393
High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk.
Chen M, Kamat AM, Huang M, Grossman HB, Dinney CP, Lerner SP, Wu X, Gu J
Carcinogenesis. 2007
PubMed ID: 17728339
Polymorphism in nucleotide excision repair gene XPC correlates with bleomycin-induced chromosomal aberrations.
Laczmanska I, Gil J, Karpinski P, Stembalska A, Trusewicz A, Pesz K, Ramsey D, Schlade-Bartusiak K, Blin N, Sasiadek MM
Environ Mol Mutagen. 2007
PubMed ID: 17685459
Polymorphism of XRCC1 predicts overall survival of gastric cancer patients receiving oxaliplatin-based chemotherapy in Chinese population.
Liu B, Wei J, Zou Z, Qian X, Nakamura T, Zhang W, Ding Y, Feng J, Yu L
Eur J Hum Genet. 2007
PubMed ID: 17593927
[Association between genetic polymorphisms of DNA repair genes XRCC1, XPD, XRCC3 and the capacity of DNA repair induce by benzene].
Xu J, Yang M, Huang H, Wang Q, et al
Wei Sheng Yan Jiu. 2007
PubMed ID: 18095557
Polymorphisms of DNA repair genes XPD and XRCC1 and risk of cataract development.
Unal M, Güven M, Batar B, Ozaydin A, Sarici A, Devranoğlu K
Exp Eye Res. 2007
PubMed ID: 17637462
Common XPD (ERCC2) polymorphisms have no measurable effect on nucleotide excision repair and basal transcription.
Lainé JP, Mocquet V, Bonfanti M, Braun C, Egly JM, Brousset P
DNA Repair (Amst). 2007
PubMed ID: 17403617
[Polymorphism Lys751Gln of XPD gene and breast cancer risk in women]
Romanowicz-Makowska H, Smolarz B
Pol Merkur Lekarski. 2007
PubMed ID: 18044339
Polymorphisms of the DNA gene XPD and risk of bladder cancer in a Southeastern Chinese population.
Shao J, Gu M, Xu Z, Hu Q, Qian L
Cancer Genet Cytogenet. 2007
PubMed ID: 17693188
Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire.
Applebaum KM, Karagas MR, Hunter DJ, Catalano PJ, Byler SH, Morris S, Nelson HH
Environ Health Perspect. 2007
PubMed ID: 17687452
A prospective study of polymorphisms of DNA repair genes XRCC1, XPD23 and APE/ref-1 and risk of stroke in Linxian, China.
Mahabir S, Abnet CC, Qiao YL, Ratnasinghe LD, Dawsey SM, Dong ZW, Taylor PR, Mark SD
J Epidemiol Community Health. 2007
PubMed ID: 17630376
Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.
McCarty KM, Smith TJ, Zhou W, Gonzalez E, Quamruzzaman Q, Rahman M, Mahiuddin G, Ryan L, Su L, Christiani DC
Carcinogenesis. 2007
PubMed ID: 17470448
Genetic susceptibility of newborn daughters to oxidative stress.
Decordier I, De Bont K, De Bock K, Mateuca R, Roelants M, Ciardelli R, Haumont D, Knudsen LE, Kirsch-Volders M
Toxicol Lett. 2007
PubMed ID: 17614221
The DNA repair gene XPD/ERCC2 polymorphisms Arg156Arg (exon 6) and Lys751Gln (exon 23) are closely associated.
Topinka J, Hertz-Picciotto I, Dostal M, Chvatalova I, Yap PS, Herr CE, Greenfield T, Sram RJ
Toxicol Lett. 2007
PubMed ID: 17604576
Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk.
De Ruyck K, Szaumkessel M, De Rudder I, Dehoorne A, Vral A, Claes K, Velghe A, Van Meerbeeck J, Thierens H
Mutat Res. 2007
PubMed ID: 17531525
Association of XPD polymorphisms with prostate cancer in Taiwanese patients.
Bau DT, Wu HC, Chiu CF, Lin CC, Hsu CM, Wang CL, Wang RF, Tsai FJ
Anticancer Res. 2007
PubMed ID: 17695467
Genetic polymorphisms of the DNA repair gene and risk of nasopharyngeal carcinoma.
Yang ZH, Du B, Wei YS, Zhang JH, Zhou B, Liang WB, Jia J, Zhang BL, Zhang L
DNA Cell Biol. 2007
PubMed ID: 17630853
Mammographic density and candidate gene variants: a twins and sisters study.
Stone J, Gurrin LC, Byrnes GB, Schroen CJ, Treloar SA, Padilla EJ, Dite GS, Southey MC, Hayes VM, Hopper JL
Cancer Epidemiol Biomarkers Prev. 2007
PubMed ID: 17627014
PAH-DNA adducts in environmentally exposed population in relation to metabolic and DNA repair gene polymorphisms.
Binkova B, Chvatalova I, Lnenickova Z, Milcova A, Tulupova E, Farmer PB, Sram RJ
Mutat Res. 2007
PubMed ID: 17412371
Nucleotide excision repair pathway genes and oral premalignant lesions.
Wang Y, Spitz MR, Lee JJ, Huang M, Lippman SM, Wu X
Clin Cancer Res. 2007
PubMed ID: 17575242
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL
Nature. 2007
PubMed ID: 17554309
Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.
Ruzzo A, Graziano F, Loupakis F, Santini D, Catalano V, Bisonni R, Ficarelli R, Fontana A, Andreoni F, Falcone A, Canestrari E, Tonini G, Mari D, Lippe P, Pizzagalli F, Schiavon G, Alessandroni P, Giustini L, Maltese P, Testa E, Menichetti ET, Magnani M
Pharmacogenomics J. 2007
PubMed ID: 17549067
XRCC1 codon 399 and ERCC2 codon 751 polymorphism, smoking, and drinking and risk of esophageal squamous cell carcinoma in a North Indian population.
Sobti RC, Singh J, Kaur P, Pachouri SS, Siddiqui EA, Bindra HS
Cancer Genet Cytogenet. 2007
PubMed ID: 17556064
Path analysis of biomarkers of exposure and early biological effects among coke-oven workers exposed to polycyclic aromatic hydrocarbons.
Qiu L, Leng S, Wang Z, Dai Y, Zheng Y, Wang Z
Cancer Epidemiol Biomarkers Prev. 2007
PubMed ID: 17548684
Reduced expression of human DNA repair genes in esophageal squamous-cell carcinoma in china.
Liu R, Yin LH, Pu YP
J Toxicol Environ Health A. 2007
PubMed ID: 17479411
XPA A23G, XPC Lys939Gln, XPD Lys751Gln and XPD Asp312Asn polymorphisms, interactions with smoking, alcohol and dietary factors, and risk of colorectal cancer.
Hansen RD, Sørensen M, Tjønneland A, Overvad K, Wallin H, Raaschou-Nielsen O, Vogel U
Mutat Res. 2007
PubMed ID: 17363013
XRCC1 and XPD polymorphisms and esophageal adenocarcinoma risk.
Liu G, Zhou W, Yeap BY, Su L, Wain JC, Poneros JM, Nishioka NS, Lynch TJ, Christiani DC
Carcinogenesis. 2007
PubMed ID: 17264068
DNA repair polymorphisms might contribute differentially on familial and sporadic breast cancer susceptibility: a study on a Portuguese population.
Costa S, Pinto D, Pereira D, Rodrigues H, Cameselle-Teijeiro J, Medeiros R, Schmitt F
Breast Cancer Res Treat. 2007
PubMed ID: 17063276
Prospective assessment of XPD Lys751Gln and XRCC1 Arg399Gln single nucleotide polymorphisms in lung cancer.
Giachino DF, Ghio P, Regazzoni S, Mandrile G, Novello S, Selvaggi G, Gregori D, DeMarchi M, Scagliotti GV
Clin Cancer Res. 2007
PubMed ID: 17504986
Polymorphisms at XPD and XRCC1 DNA repair loci and increased risk of oral leukoplakia and cancer among NAT2 slow acetylators.
Majumder M, Sikdar N, Ghosh S, Roy B
Int J Cancer. 2007
PubMed ID: 17290401
A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population.
Yin J, Vogel U, Ma Y, Qi R, Sun Z, Wang H
Cancer Genet Cytogenet. 2007
PubMed ID: 17498557
DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma.
Povey JE, Darakhshan F, Robertson K, Bisset Y, Mekky M, Rees J, Doherty V, Kavanagh G, Anderson N, Campbell H, MacKie RM, Melton DW
Carcinogenesis. 2007
PubMed ID: 17210993
Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials.
Kuptsova N, Kopecky KJ, Godwin J, Anderson J, Hoque A, Willman CL, Slovak ML, Ambrosone CB
Blood. 2007
PubMed ID: 17197435
Single nucleotide polymorphisms and expression of ERCC1 and ERCC2 vis-à-vis chemotherapy drug cytotoxicity in human glioma.
Chen H, Shao C, Shi H, Mu Y, Sai K, Chen Z
J Neurooncol. 2007
PubMed ID: 17151930
Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair.
Coin F, Oksenych V, Egly JM
Mol Cell. 2007
PubMed ID: 17466626
XRCC1 and XPD gene polymorphisms in a South Indian population.
Vettriselvi V, Vijayalakshmi K, Solomon PF, Venkatachalam P
Asian Pac J Cancer Prev. 2007
PubMed ID: 17696747
Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.
Ruzzo A, Graziano F, Loupakis F, Rulli E, Canestrari E, Santini D, Catalano V, Ficarelli R, Maltese P, Bisonni R, Masi G, Schiavon G, Giordani P, Giustini L, Falcone A, Tonini G, Silva R, Mattioli R, Floriani I, Magnani M
J Clin Oncol. 2007
PubMed ID: 17401013
Polymorphisms of phase II xenobiotic-metabolizing and DNA repair genes and in vitro N-ethyl-N-nitrosourea-induced O6-ethylguanine levels in human lymphocytes.
Jiao L, Chang P, Firozi PF, Lai D, Abbruzzese JL, Li D
Mutat Res. 2007
PubMed ID: 17158087
[Analysis for the association between genetic polymorphisms of XRCC1, XPD, XRCC3, CCND1 and the latency of the occupational chronic benzene poisoning]
Xu JN, Huang HL, Wang QK, Wang YW, Yang M, Zheng YX
Zhonghua Yu Fang Yi Xue Za Zhi. 2007
PubMed ID: 17605237
A pharmacogenomic study of docetaxel and gemcitabine for the initial treatment of advanced non-small cell lung cancer.
Petty WJ, Knight SN, Mosley L, Lovato J, Capellari J, Tucker R, Blackstock AW, Miller MS, Miller AA
J Thorac Oncol. 2007
PubMed ID: 17410042
Association between polymorphisms of biotransformation and DNA-repair genes and risk of colorectal cancer in Taiwan.
Yeh CC, Sung FC, Tang R, Chang-Chieh CR, Hsieh LL
J Biomed Sci. 2007
PubMed ID: 17191090
Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation.
Vangsted A, Gimsing P, Klausen TW, Nexø BA, Wallin H, Andersen P, Hokland P, Lillevang ST, Vogel U
Int J Cancer. 2007
PubMed ID: 17131345
Polymorphism in the ERCC2 codon 751 is associated with arsenic-induced premalignant hyperkeratosis and significant chromosome aberrations.
Banerjee M, Sarkar J, Das JK, Mukherjee A, Sarkar AK, Mondal L, Giri AK
Carcinogenesis. 2007
PubMed ID: 17050553
Importance of xeroderma pigmentosum group D polymorphisms in susceptibility to ovarian cancer.
Costa S, Pinto D, Pereira D, Vasconcelos A, Afonso-Lopes C, Osório T, Lopes C, Medeiros R
Cancer Lett. 2007
PubMed ID: 16677755
Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.
Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Mäkelä TP, Schneider MD
Cell Metab. 2007
PubMed ID: 17276355
A common genetic variant in XPD associates with risk of 5q- and 7q-deleted acute myeloid leukemia.
Smith AG, Worrillow LJ, Allan JM
Blood. 2007
PubMed ID: 17023576
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.
Jiao L, Hassan MM, Bondy ML, Abbruzzese JL, Evans DB, Li D
Cancer Lett. 2007
PubMed ID: 16458430
XPD Lys751Gln polymorphism analysis in women with sporadic breast cancer.
Romanowicz-Makowska H, Sobczuk A, Smolarz B, Fiks T, Kulig A
Pol J Pathol. 2007
PubMed ID: 18459458
Single nucleotide polymorphisms in nucleotide excision repair genes XPA, XPD, XPG and ERCC1 in advanced colorectal cancer patients treated with first-line oxaliplatin/fluoropyrimidine.
Monzo M, Moreno I, Navarro A, Ibeas R, Artells R, Gel B, Martinez F, Moreno J, Hernandez R, Navarro-Vigo M
Oncology. 2007
PubMed ID: 18204222
Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of northern Spain.
López-Cima MF, González-Arriaga P, García-Castro L, Pascual T, Marrón MG, Puente XS, Tardón A
BMC Cancer. 2007
PubMed ID: 17705814
Polymorphisms in genes involved in DNA repair and metabolism of xenobiotics in individual susceptibility to sporadic diffuse gastric cancer.
Ruzzo A, Canestrari E, Maltese P, Pizzagalli F, Graziano F, Santini D, Catalano V, Ficarelli R, Mari D, Bisonni R, Giordani P, Giustini L, Lippe P, Silva R, Mattioli R, Torresi U, Latini L, Magnani M
Clin Chem Lab Med. 2007
PubMed ID: 17617021
Polymorphisms in XPD, XPC and the risk of death in patients with urinary bladder neoplasms.
Sanyal S, De Verdier PJ, Steineck G, Larsson P, Onelöv E, Hemminki K, Kumar R
Acta Oncol. 2007
PubMed ID: 17438703
Association between nucleotide excision repair gene polymorphisms and chromosomal damage in coke-oven workers.
Cheng J, Leng S, Dai Y, Huang C, Pan Z, Niu Y, Li B, Zheng Y
Biomarkers. 2007
PubMed ID: 17438655
Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis.
Kiyohara C, Yoshimasu K
Int J Med Sci. 2007
PubMed ID: 17299578
Polymorphisms of DNA repair genes XRCC1 and XPD and risk of primary open angle glaucoma (POAG).
Güven M, Unal M, Batar B, Eroğlu E, Devaroğlu K, Tamçelik N, Uçar D, Sarici A
Mol Vis. 2007
PubMed ID: 17242676
Breast cancer risk is not associated with polymorphic forms of xeroderma pigmentosum genes in a cohort of women from Washington County, Maryland.
Jorgensen TJ, Visvanathan K, Ruczinski I, Thuita L, Hoffman S, Helzlsouer KJ
Breast Cancer Res Treat. 2007
PubMed ID: 16823510
Genetic polymorphisms and haplotypes of DNA repair genes in childhood acute lymphoblastic leukemia.
Pakakasama S, Sirirat T, Kanchanachumpol S, Udomsubpayakul U, Mahasirimongkol S, Kitpoka P, Thithapandha A, Hongeng S
Pediatr Blood Cancer. 2007
PubMed ID: 16435384
Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice.
van de Ven M, Andressoo JO, Holcomb VB, von Lindern M, Jong WM, De Zeeuw CI, Suh Y, Hasty P, Hoeijmakers JH, van der Horst GT, Mitchell JR
PLoS Genet. 2006
PubMed ID: 17173483
Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis.
Li C, Hu Z, Liu Z, Wang LE, Strom SS, Gershenwald JE, Lee JE, Ross MI, Mansfield PF, Cormier JN, Prieto VG, Duvic M, Grimm EA, Wei Q
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 17164380
XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma risk.
Stern MC, Siegmund KD, Conti DV, Corral R, Haile RW
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 17164360
Polymorphisms in the thymidylate synthase promoter and the DNA repair genes XRCC1 and XPD in a Brazilian population.
Canalle R, da Silva S Andrade V, Scrideli CA, de Paula Queiroz RG, Tone LG
Environ Mol Mutagen. 2006
PubMed ID: 17111423
Influence of polymorphisms in xenobiotic-metabolizing genes and DNA-repair genes on diepoxybutane-induced SCE frequency.
Laczmanska I, Gil J, Karpinski P, Stembalska A, Kozlowska J, Busza H, Trusewicz A, Pesz K, Ramsey D, Schlade-Bartusiak K, Blin N, Sasiadek MM
Environ Mol Mutagen. 2006
PubMed ID: 17078101
Influence of DNA repair gene polymorphisms of hOGG1, XRCC1, XRCC3, ERCC2 and the folate metabolism gene MTHFR on chromosomal aberration frequencies.
Skjelbred CF, Svendsen M, Haugan V, Eek AK, Clausen KO, Svendsen MV, Hansteen IL
Mutat Res. 2006
PubMed ID: 16997330
XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer.
Chung HH, Kim MK, Kim JW, Park NH, Song YS, Kang SB, Lee HP
Gynecol Oncol. 2006
PubMed ID: 16875718
DNA nucleotide excision repair-dependent signaling to checkpoint activation.
Marini F, Nardo T, Giannattasio M, Minuzzo M, Stefanini M, Plevani P, Muzi Falconi M
Proc Natl Acad Sci U S A. 2006
PubMed ID: 17088560
A phase II study of irinotecan and carboplatin in advanced non-small cell lung cancer with pharmacogenomic analysis: final report.
Pillot GA, Read WL, Hennenfent KL, Marsh S, Gao F, Viswanathan A, Cummings K, McLeod HL, Govindan R
J Thorac Oncol. 2006
PubMed ID: 17409981
[Association between nucleotide excision repair gene polymorphisms and chromosomal damage in coke-oven workers]
Cheng J, Leng SG, Dai YF, Pan ZF, Niu Y, Li B, Zheng YX
Zhonghua Yu Fang Yi Xue Za Zhi. 2006
PubMed ID: 17313739
Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers.
Gao WM, Romkes M, Siegfried JM, Luketich JD, Keohavong P
Mol Carcinog. 2006
PubMed ID: 16865671
Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy.
Zárate RN, Arias F, Bandres E, Cubedo E, Malumbres R, García-Foncillas J
World J Gastroenterol. 2006
PubMed ID: 17009404
Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium.
Breast Cancer Association Consortium
J Natl Cancer Inst. 2006
PubMed ID: 17018785
Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.
Andressoo JO, Jans J, de Wit J, Coin F, Hoogstraten D, van de Ven M, Toussaint W, Huijmans J, Thio HB, van Leeuwen WJ, de Boer J, Egly JM, Hoeijmakers JH, van der Horst GT, Mitchell JR
PLoS Biol. 2006
PubMed ID: 17020410
Genetic polymorphisms of the XPG and XPD nucleotide excision repair genes in sarcoma patients.
Le Morvan V, Longy M, Bonaïti-Pellié C, Bui B, Houédé N, Coindre JM, Robert J, Pourquier P
Int J Cancer. 2006
PubMed ID: 16646069
Identification and Herc5-mediated ISGylation of novel target proteins.
Takeuchi T, Inoue S, Yokosawa H
Biochem Biophys Res Commun. 2006
PubMed ID: 16884686
DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.
Quintela-Fandino M, Hitt R, Medina PP, Gamarra S, Manso L, Cortes-Funes H, Sanchez-Cespedes M
J Clin Oncol. 2006
PubMed ID: 16896002
Influence of polymorphism in DNA repair and defence genes on p53 mutations in bladder tumours.
Ryk C, Kumar R, Sanyal S, de Verdier PJ, Hemminki K, Larsson P, Steineck G, Hou SM
Cancer Lett. 2006
PubMed ID: 16343742
Single nucleotide polymorphisms in DNA repair genes might be prognostic factors in muscle-invasive bladder cancer patients treated with chemoradiotherapy.
Sakano S, Wada T, Matsumoto H, Sugiyama S, Inoue R, Eguchi S, Ito H, Ohmi C, Matsuyama H, Naito K
Br J Cancer. 2006
PubMed ID: 16880786
Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer.
Shen J, Desai M, Agrawal M, Kennedy DO, Senie RT, Santella RM, Terry MB
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 16985021
Polymorphisms in the DNA repair genes XPD (ERCC2) and XPF (ERCC4) are not associated with sporadic late-onset Alzheimer's disease.
Dogru-Abbasoglu S, Inceoglu M, Parildar-Karpuzoglu H, Hanagasi HA, Karadag B, Gurvit H, Emre M, Aykac-Toker G, Uysal M
Neurosci Lett. 2006
PubMed ID: 16806697
DNA repair gene polymorphisms and probability of p53 mutation in bladder cancer.
Stern MC, Conway K, Li Y, Mistry K, Taylor JA
Mol Carcinog. 2006
PubMed ID: 16652373
The XPD 751Gln allele is associated with an increased risk for esophageal adenocarcinoma: a population-based case-control study in Sweden.
Ye W, Kumar R, Bacova G, Lagergren J, Hemminki K, Nyrén O
Carcinogenesis. 2006
PubMed ID: 16571649
Influence of DNA repair polymorphisms on biomarkers of genotoxic damage in peripheral lymphocytes of healthy subjects.
Zijno A, Verdina A, Galati R, Leopardi P, Marcon F, Andreoli C, Rossi S, Crebelli R
Mutat Res. 2006
PubMed ID: 16824555
XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review.
Manuguerra M, Saletta F, Karagas MR, Berwick M, Veglia F, Vineis P, Matullo G
Am J Epidemiol. 2006
PubMed ID: 16707649
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria.
Andressoo JO, Mitchell JR, de Wit J, Hoogstraten D, Volker M, Toussaint W, Speksnijder E, Beems RB, van Steeg H, Jans J, de Zeeuw CI, Jaspers NG, Raams A, Lehmann AR, Vermeulen W, Hoeijmakers JH, van der Horst GT
Cancer Cell. 2006
PubMed ID: 16904611
Polymorphism of the DNA repair gene ERCC2 Lys751Gln and risk of lung cancer in a northeastern Chinese population.
Yin J, Vogel U, Ma Y, Guo L, Wang H, Qi R
Cancer Genet Cytogenet. 2006
PubMed ID: 16875933
Polymorphisms in DNA repair genes as risk factors for asbestos-related malignant mesothelioma in a general population study.
Dianzani I, Gibello L, Biava A, Giordano M, Bertolotti M, Betti M, Ferrante D, Guarrera S, Betta GP, Mirabelli D, Matullo G, Magnani C
Mutat Res. 2006
PubMed ID: 16564556
[Association between polymorphisms of XPD gene and susceptibility to chronic benzene poisoning]
Huang HL, Xu JN, Wang QK, Wang YW, Yang M, Chen Y, Li GL
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006
PubMed ID: 16889696
Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the transcription factor IIH complex and risk of lung cancer: a case-control analysis in a Chinese population.
Hu Z, Xu L, Shao M, Yuan J, Wang Y, Wang F, Yuan W, Qian J, Ma H, Wang Y, Liu H, Chen W, Yang L, Jing G, Huo X, Chen F, Jin L, Wei Q, Wu T, Lu D, Huang W, Shen H
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 16835333
Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma among women in Connecticut.
Shen M, Zheng T, Lan Q, Zhang Y, Zahm SH, Wang SS, Holford TR, Leaderer B, Yeager M, Welch R, Kang D, Boyle P, Zhang B, Zou K, Zhu Y, Chanock S, Rothman N
Hum Genet. 2006
PubMed ID: 16738949
XPD common variants and their association with melanoma and breast cancer risk.
Debniak T, Scott RJ, Huzarski T, Byrski T, Masojć B, van de Wetering T, Serrano-Fernandez P, Górski B, Cybulski C, Gronwald J, Debniak B, Maleszka R, Kładny J, Bieniek A, Nagay L, Haus O, Grzybowska E, Wandzel P, Niepsuj S, Narod SA, Lubinski J
Breast Cancer Res Treat. 2006
PubMed ID: 16685590
Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study.
Mechanic LE, Millikan RC, Player J, de Cotret AR, Winkel S, Worley K, Heard K, Heard K, Tse CK, Keku T
Carcinogenesis. 2006
PubMed ID: 16399771
Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia.
Monzo M, Brunet S, Urbano-Ispizua A, Navarro A, Perea G, Esteve J, Artells R, Granell M, Berlanga J, Ribera JM, Bueno J, Llorente A, Guardia R, Tormo M, Torres P, Nomdedéu JF, Montserrat E, Sierra J, CETLAM
Blood. 2006
PubMed ID: 16507781
Xeroderma pigmentosum group D haplotype predicts for response, survival, and toxicity after platinum-based chemotherapy in advanced nonsmall cell lung cancer.
Booton R, Ward T, Heighway J, Taylor P, Power F, Ashcroft L, Morris J, Thatcher N
Cancer. 2006
PubMed ID: 16649224
Effect of DNA repair protein Rad18 on viral infection.
Lloyd AG, Tateishi S, Bieniasz PD, Muesing MA, Yamaizumi M, Mulder LC
PLoS Pathog. 2006
PubMed ID: 16710452
Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility.
Andrew AS, Nelson HH, Kelsey KT, Moore JH, Meng AC, Casella DP, Tosteson TD, Schned AR, Karagas MR
Carcinogenesis. 2006
PubMed ID: 16311243
DNA repair polymorphisms and cancer risk in non-smokers in a cohort study.
Matullo G, Dunning AM, Guarrera S, Baynes C, Polidoro S, Garte S, Autrup H, Malaveille C, Peluso M, Airoldi L, Veglia F, Gormally E, Hoek G, Krzyzanowski M, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Linseisen J, Boeing H, Trichopoulou A, Palli D, Krogh V, Tumino R, Panico S, Bueno-De-Mesquita HB, Peeters PH, Lund E, Pera G, Martinez C, Dorronsoro M, Barricarte A, Tormo MJ, Quiros JR, Day NE, Key TJ, Saracci R, Kaaks R, Riboli E, Vineis P
Carcinogenesis. 2006
PubMed ID: 16308313
Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy.
Ruzzo A, Graziano F, Kawakami K, Watanabe G, Santini D, Catalano V, Bisonni R, Canestrari E, Ficarelli R, Menichetti ET, Mari D, Testa E, Silva R, Vincenzi B, Giordani P, Cascinu S, Giustini L, Tonini G, Magnani M
J Clin Oncol. 2006
PubMed ID: 16622263
Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer.
Damaraju S, Murray D, Dufour J, Carandang D, Myrehaug S, Fallone G, Field C, Greiner R, Hanson J, Cass CE, Parliament M
Clin Cancer Res. 2006
PubMed ID: 16638864
Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.
Dollé ME, Busuttil RA, Garcia AM, Wijnhoven S, van Drunen E, Niedernhofer LJ, van der Horst G, Hoeijmakers JH, van Steeg H, Vijg J
Mutat Res. 2006
PubMed ID: 16472827
Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.
Moreno V, Gemignani F, Landi S, Gioia-Patricola L, Chabrier A, Blanco I, González S, Guino E, Capellà G, Canzian F
Clin Cancer Res. 2006
PubMed ID: 16609022
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients.
de las Peñas R, Sanchez-Ronco M, Alberola V, Taron M, Camps C, Garcia-Carbonero R, Massuti B, Queralt C, Botia M, Garcia-Gomez R, Isla D, Cobo M, Santarpia M, Cecere F, Mendez P, Sanchez JJ, Rosell R, Spanish Lung Cancer Group
Ann Oncol. 2006
PubMed ID: 16407418
Single nucleotide polymorphisms of DNA repair genes XRCC1 and XPD and its molecular mapping in Indian oral cancer.
Ramachandran S, Ramadas K, Hariharan R, Rejnish Kumar R, Radhakrishna Pillai M
Oral Oncol. 2006
PubMed ID: 16324877
[XRCC1 and XPD genetic polymorphisms predict clinical responses to platinum-based chemotherapy in advanced non-small cell lung cancer]
Yuan P, Miao XP, Zhang XM, Wang ZH, Tan W, Sun Y, Zhang XR, Xu BH, Lin DX
Zhonghua Zhong Liu Za Zhi. 2006
PubMed ID: 16875604
Genetic variation in the nucleotide excision repair pathway and bladder cancer risk.
García-Closas M, Malats N, Real FX, Welch R, Kogevinas M, Chatterjee N, Pfeiffer R, Silverman D, Dosemeci M, Tardón A, Serra C, Carrato A, García-Closas R, Castaño-Vinyals G, Chanock S, Yeager M, Rothman N
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 16537713
Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.
Wu X, Gu J, Grossman HB, Amos CI, Etzel C, Huang M, Zhang Q, Millikan RE, Lerner S, Dinney CP, Spitz MR
Am J Hum Genet. 2006
PubMed ID: 16465622
Polymorphisms in nucleotide excision repair genes and risk of multiple primary melanoma: the Genes Environment and Melanoma Study.
Millikan RC, Hummer A, Begg C, Player J, de Cotret AR, Winkel S, Mohrenweiser H, Thomas N, Armstrong B, Kricker A, Marrett LD, Gruber SB, Culver HA, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Busam K, From L, Mujumdar U, Berwick M
Carcinogenesis. 2006
PubMed ID: 16258177
Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.
Zienolddiny S, Campa D, Lind H, Ryberg D, Skaug V, Stangeland L, Phillips DH, Canzian F, Haugen A
Carcinogenesis. 2006
PubMed ID: 16195237
Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.
Huang WY, Berndt SI, Kang D, Chatterjee N, Chanock SJ, Yeager M, Welch R, Bresalier RS, Weissfeld JL, Hayes RB
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 16492920
Variation in DNA repair genes ERCC2, XRCC1, and XRCC3 and risk of follicular lymphoma.
Smedby KE, Lindgren CM, Hjalgrim H, Humphreys K, Schöllkopf C, Chang ET, Roos G, Ryder LP, Falk KI, Palmgren J, Kere J, Melbye M, Glimelius B, Adami HO
Cancer Epidemiol Biomarkers Prev. 2006
PubMed ID: 16492913
Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage.
Naccarati A, Soucek P, Stetina R, Haufroid V, Kumar R, Vodickova L, Trtkova K, Dusinska M, Hemminki K, Vodicka P
Mutat Res. 2006
PubMed ID: 16043197
Association between DNA repair gene polymorphisms and p53 alterations in Japanese patients with muscle-invasive bladder cancer.
Sakano S, Matsumoto H, Yamamoto Y, Kawai Y, Eguchi S, Ohmi C, Matsuyama H, Naito K
Pathobiology. 2006
PubMed ID: 17374967
SNP-SNP interactions in breast cancer susceptibility.
Onay VU, Briollais L, Knight JA, Shi E, Wang Y, Wells S, Li H, Rajendram I, Andrulis IL, Ozcelik H
BMC Cancer. 2006
PubMed ID: 16672066
Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study.
Skjelbred CF, Saebø M, Wallin H, Nexø BA, Hagen PC, Lothe IM, Aase S, Johnson E, Hansteen IL, Vogel U, Kure EH
BMC Cancer. 2006
PubMed ID: 16542436
Polymorphism in DNA repair genes and oral squamous cell carcinoma in Thailand.
Kietthubthew S, Sriplung H, Au WW, Ishida T
Int J Hyg Environ Health. 2006
PubMed ID: 16373199
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relationship to breast cancer risk and familial predisposition to breast cancer.
Brewster AM, Jorgensen TJ, Ruczinski I, Huang HY, Hoffman S, Thuita L, Newschaffer C, Lunn RM, Bell D, Helzlsouer KJ
Breast Cancer Res Treat. 2006
PubMed ID: 16319991
XPD Lys751Gln polymorphism in the etiology and outcome of childhood acute myeloid leukemia: a Children's Oncology Group report.
Mehta PA, Alonzo TA, Gerbing RB, Elliott JS, Wilke TA, Kennedy RJ, Ross JA, Perentesis JP, Lange BJ, Davies SM, Children's Oncology Group
Blood. 2006
PubMed ID: 16150943
DNA repair gene polymorphisms and risk of second primary neoplasms and mortality in oral cancer patients.
Gal TJ, Huang WY, Chen C, Hayes RB, Schwartz SM
Laryngoscope. 2005
PubMed ID: 16369171
[Correlation of genetic polymorphisms in nucleotide excision repair system to sensitivity of advanced non-small cell lung cancer patients to platinum-based chemotherapy]
Yuan P, Miao XP, Zhang XM, Wang ZH, Tan W, Zhang XR, Sun Y, Xu BH, Lin DX
Ai Zheng. 2005
PubMed ID: 16351803
Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mamm Genome. 2005
PubMed ID: 16341674
Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma.
Chen CC, Yang SY, Liu CJ, Lin CL, Liaw YF, Lin SM, Lee SD, Chen PJ, Chen CJ, Yu MW
Int J Epidemiol. 2005
PubMed ID: 16172101
Accelerated aging pathology in ad libitum fed Xpd(TTD) mice is accompanied by features suggestive of caloric restriction.
Wijnhoven SW, Beems RB, Roodbergen M, van den Berg J, Lohman PH, Diderich K, van der Horst GT, Vijg J, Hoeijmakers JH, van Steeg H
DNA Repair (Amst). 2005
PubMed ID: 16115803
Polymorphisms/haplotypes in DNA repair genes and smoking: a bladder cancer case-control study.
Matullo G, Guarrera S, Sacerdote C, Polidoro S, Davico L, Gamberini S, Karagas M, Casetta G, Rolle L, Piazza A, Vineis P
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 16284380
Interindividual variation in nucleotide excision repair genes and risk of endometrial cancer.
Weiss JM, Weiss NS, Ulrich CM, Doherty JA, Voigt LF, Chen C
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 16284373
DNA repair polymorphisms and risk of colorectal adenomatous or hyperplastic polyps.
Bigler J, Ulrich CM, Kawashima T, Whitton J, Potter JD
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 16284370
Association of polymorphisms in ERCC2 gene with non-familial thyroid cancer risk.
Silva SN, Gil OM, Oliveira VC, Cabral MN, Azevedo AP, Faber A, Manita I, Ferreira TC, Limbert E, Pina JE, Rueff J, Gaspar J
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 16214924
ERCC1 and ERCC2 polymorphisms and adult glioma.
Wrensch M, Kelsey KT, Liu M, Miike R, Moghadassi M, Sison JD, Aldape K, McMillan A, Wiemels J, Wiencke JK
Neuro Oncol. 2005
PubMed ID: 16212814
Influence of DNA repair gene polymorphisms on the yield of chromosomal aberrations.
Kiuru A, Lindholm C, Heilimo I, Ceppi M, Koivistoinen A, Ilus T, Hirvonen A, Norppa H, Salomaa S
Environ Mol Mutagen. 2005
PubMed ID: 15971256
Polymorphisms in the human XPD (ERCC2) gene, DNA repair capacity and cancer susceptibility: an appraisal.
Clarkson SG, Wood RD
DNA Repair (Amst). 2005
PubMed ID: 16054878
Polymorphisms in the DNA nucleotide excision repair genes and lung cancer risk in Xuan Wei, China.
Shen M, Berndt SI, Rothman N, Demarini DM, Mumford JL, He X, Bonner MR, Tian L, Yeager M, Welch R, Chanock S, Zheng T, Caporaso N, Lan Q
Int J Cancer. 2005
PubMed ID: 15849729
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Genetic polymorphisms and the effect of cigarette smoking in the comet assay.
Hoffmann H, Isner C, Högel J, Speit G
Mutagenesis. 2005
PubMed ID: 16037119
Single nucleotide polymorphisms for DNA repair genes in breast cancer patients.
Zhang L, Zhang Z, Yan W
Clin Chim Acta. 2005
PubMed ID: 16002061
DNA repair and cyclin D1 polymorphisms and styrene-induced genotoxicity and immunotoxicity.
Kuricova M, Naccarati A, Kumar R, Koskinen M, Sanyal S, Dusinska M, Tulinska J, Vodickova L, Liskova A, Jahnova E, Fuortes L, Haufroid V, Hemminki K, Vodicka P
Toxicol Appl Pharmacol. 2005
PubMed ID: 15992842
Polymorphisms in DNA repair genes in the molecular pathogenesis of esophageal (Barrett) adenocarcinoma.
Casson AG, Zheng Z, Evans SC, Veugelers PJ, Porter GA, Guernsey DL
Carcinogenesis. 2005
PubMed ID: 15878910
Influence of polymorphisms in DNA repair genes XPD, XRCC1 and MGMT on DNA damage induced by gamma radiation and its repair in lymphocytes in vitro.
Rzeszowska-Wolny J, Polanska J, Pietrowska M, Palyvoda O, Jaworska J, Butkiewicz D, Hancock R
Radiat Res. 2005
PubMed ID: 16038584
Selected DNA repair polymorphisms and gastric cancer in Poland.
Huang WY, Chow WH, Rothman N, Lissowska J, Llaca V, Yeager M, Zatonski W, Hayes RB
Carcinogenesis. 2005
PubMed ID: 15802298
Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer.
Laska MJ, Nexø BA, Vistisen K, Poulsen HE, Loft S, Vogel U
Cancer Lett. 2005
PubMed ID: 15885892
Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.
Kuschel B, Chenevix-Trench G, Spurdle AB, Chen X, Hopper JL, Giles GG, McCredie M, Chang-Claude J, Gregory CS, Day NE, Easton DF, Ponder BA, Dunning AM, Pharoah PD
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 16030124
Selected genetic polymorphisms in MGMT, XRCC1, XPD, and XRCC3 and risk of head and neck cancer: a pooled analysis.
Huang WY, Olshan AF, Schwartz SM, Berndt SI, Chen C, Llaca V, Chanock SJ, Fraumeni JF, Hayes RB
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 16030112
Association between polymorphisms in the DNA repair genes, XRCC1, APE1, and XPD and acute side effects of radiotherapy in breast cancer patients.
Chang-Claude J, Popanda O, Tan XL, Kropp S, Helmbold I, von Fournier D, Haase W, Sautter-Bihl ML, Wenz F, Schmezer P, Ambrosone CB
Clin Cancer Res. 2005
PubMed ID: 16000577
Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.
Compe E, Drané P, Laurent C, Diderich K, Braun C, Hoeijmakers JH, Egly JM
Mol Cell Biol. 2005
PubMed ID: 15988019
Basal cell carcinoma and variants in genes coding for immune response, DNA repair, folate and iron metabolism.
Festa F, Kumar R, Sanyal S, Undén B, Nordfors L, Lindholm B, Snellman E, Schalling M, Försti A, Hemminki K
Mutat Res. 2005
PubMed ID: 15914210
Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer.
Broberg K, Björk J, Paulsson K, Höglund M, Albin M
Carcinogenesis. 2005
PubMed ID: 15746160
The impact of genetic factors on the incidence of multiple primary tumors (MPT) of the head and neck.
Rydzanicz M, Wierzbicka M, Gajecka M, Szyfter W, Szyfter K
Cancer Lett. 2005
PubMed ID: 15914277
Polymorphisms in DNA repair genes as risk factors for spina bifida and orofacial clefts.
Olshan AF, Shaw GM, Millikan RC, Laurent C, Finnell RH
Am J Med Genet A. 2005
PubMed ID: 15887293
The DNA repair gene ERCC2/XPD polymorphism Arg 156Arg (A22541C) and risk of lung cancer in a Chinese population.
Yin J, Li J, Ma Y, Guo L, Wang H, Vogel U
Cancer Lett. 2005
PubMed ID: 15896456
Genetic variation in XPD, sun exposure, and risk of skin cancer.
Han J, Colditz GA, Liu JS, Hunter DJ
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 15941969
Polymorphisms in GLTSCR1 and ERCC2 are associated with the development of oligodendrogliomas.
Yang P, Kollmeyer TM, Buckner K, Bamlet W, Ballman KV, Jenkins RB
Cancer. 2005
PubMed ID: 15834925
Combinations of polymorphisms in XPD, XPC and XPA in relation to risk of lung cancer.
Vogel U, Overvad K, Wallin H, Tjønneland A, Nexø BA, Raaschou-Nielsen O
Cancer Lett. 2005
PubMed ID: 15837542
Obesity and genetic polymorphism of ERCC2 and ERCC4 as modifiers of risk of breast cancer.
Lee SA, Lee KM, Park WY, Kim B, Nam J, Yoo KY, Noh DY, Ahn SH, Hirvonen A, Kang D
Exp Mol Med. 2005
PubMed ID: 15886521
[Polymorphisms in nucleotide excision repair genes XPC and XPD and clinical responses to platinum-based chemotherapy in advanced non-small cell lung cancer]
Yuan P, Miao XP, Zhang XM, Wang ZH, Tan W, Sun Y, Xu BH, Lin DX
Zhonghua Yi Xue Za Zhi. 2005
PubMed ID: 16061005
Genotyping of patients with sporadic and radiation-associated meningiomas.
Sadetzki S, Flint-Richter P, Starinsky S, Novikov I, Lerman Y, Goldman B, Friedman E
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 15824172
Polymorphisms in XPD exons 10 and 23 and bladder cancer risk.
Schabath MB, Delclos GL, Grossman HB, Wang Y, Lerner SP, Chamberlain RM, Spitz MR, Wu X
Cancer Epidemiol Biomarkers Prev. 2005
PubMed ID: 15824159
Polymorphism in the nuclear excision repair gene ERCC2/XPD: association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma.
Lovatt T, Alldersea J, Lear JT, Hoban PR, Ramachandran S, Fryer AA, Smith AG, Strange RC
Hum Mutat. 2005
PubMed ID: 15776433
Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.
Buch S, Zhu B, Davis AG, Odom D, Siegfried JM, Grandis JR, Romkes M
Mol Carcinog. 2005
PubMed ID: 15754315
SNP genotyping using microsphere-linked PNA and flow cytometric detection.
Rockenbauer E, Petersen K, Vogel U, Bolund L, Kølvraa S, Nielsen KV, Nexø BA
Cytometry A. 2005
PubMed ID: 15729710
Genotype phenotype correlations in Israeli colorectal cancer patients.
Starinsky S, Figer A, Ben-Asher E, Geva R, Flex D, Fidder HH, Zidan J, Lancet D, Friedman E
Int J Cancer. 2005
PubMed ID: 15523694
Nucleotide excision repair gene polymorphisms and recurrence after treatment for superficial bladder cancer.
Gu J, Zhao H, Dinney CP, Zhu Y, Leibovici D, Bermejo CE, Grossman HB, Wu X
Clin Cancer Res. 2005
PubMed ID: 15746040
Impact of gene polymorphisms on clinical outcome for stage IV melanoma patients treated with biochemotherapy: an exploratory study.
Liu D, O'Day SJ, Yang D, Boasberg P, Milford R, Kristedja T, Groshen S, Weber J
Clin Cancer Res. 2005
PubMed ID: 15709194
Polymorphisms of the XRCC1, XRCC3, & XPD genes, and colorectal cancer risk: a case-control study in Taiwan.
Yeh CC, Sung FC, Tang R, Chang-Chieh CR, Hsieh LL
BMC Cancer. 2005
PubMed ID: 15679883
Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
Nature. 2005
PubMed ID: 15635413
DNA repair gene polymorphisms and susceptibility to familial breast cancer in a group of patients from Campinas, Brazil.
Dufloth RM, Costa S, Schmitt F, Zeferino LC
Genet Mol Res. 2005
PubMed ID: 16475125
XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study.
Metsola K, Kataja V, Sillanpää P, Siivola P, Heikinheimo L, Eskelinen M, Kosma VM, Uusitupa M, Hirvonen A
Breast Cancer Res. 2005
PubMed ID: 16280050
Polymorphisms of DNA repair gene XPD and DNA damage of workers exposed to vinylchloride monomer.
Zhu S, Wang A, Xia Z
Int J Hyg Environ Health. 2005
PubMed ID: 16217922
Effect of polymorphisms in XPD, RAI, ASE-1 and ERCC1 on the risk of basal cell carcinoma among Caucasians after age 50.
Vogel U, Olsen A, Wallin H, Overvad K, Tjønneland A, Nexø BA
Cancer Detect Prev. 2005
PubMed ID: 15936590
ERCC2 /XPD gene polymorphisms and lung cancer: a HuGE review.
Benhamou S, Sarasin A
Am J Epidemiol. 2005
PubMed ID: 15615908
Interethnic variability of ERCC2 polymorphisms.
King CR, Yu J, Freimuth RR, McLeod HL, Marsh S
Pharmacogenomics J. 2005
PubMed ID: 15534626
Reduced nucleotide excision repair and GSTM1-null genotypes influence anti-B[a]PDE-DNA adduct levels in mononuclear white blood cells of highly PAH-exposed coke oven workers.
Pavanello S, Pulliero A, Siwinska E, Mielzynska D, Clonfero E
Carcinogenesis. 2005
PubMed ID: 15471894
Genetic variation in XPD predicts treatment outcome and risk of acute myeloid leukemia following chemotherapy.
Allan JM, Smith AG, Wheatley K, Hills RK, Travis LB, Hill DA, Swirsky DM, Morgan GJ, Wild CP
Blood. 2004
PubMed ID: 15339847
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
ERCC2 genotypes and a corresponding haplotype are linked with breast cancer risk in a German population.
Justenhoven C, Hamann U, Pesch B, Harth V, Rabstein S, Baisch C, Vollmert C, Illig T, Ko YD, Brüning T, Brauch H
Cancer Epidemiol Biomarkers Prev. 2004
PubMed ID: 15598761
Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer risk.
Terry MB, Gammon MD, Zhang FF, Eng SM, Sagiv SK, Paykin AB, Wang Q, Hayes S, Teitelbaum SL, Neugut AI, Santella RM
Cancer Epidemiol Biomarkers Prev. 2004
PubMed ID: 15598760
Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer.
Popanda O, Schattenberg T, Phong CT, Butkiewicz D, Risch A, Edler L, Kayser K, Dienemann H, Schulz V, Drings P, Bartsch H, Schmezer P
Carcinogenesis. 2004
PubMed ID: 15333465
Selective regulation of vitamin D receptor-responsive genes by TFIIH.
Drané P, Compe E, Catez P, Chymkowitch P, Egly JM
Mol Cell. 2004
PubMed ID: 15494306
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Polymorphisms in the DNA repair gene XPD and susceptibility to esophageal squamous cell carcinoma.
Yu HP, Wang XL, Sun X, Su YH, Wang YJ, Lu B, Shi LY, Xiong CL, Li YY, Li F, Xu SQ
Cancer Genet Cytogenet. 2004
PubMed ID: 15381366
Genomic analysis of mouse retinal development.
Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
PLoS Biol. 2004
PubMed ID: 15226823
Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients.
Shi Q, Wang LE, Bondy ML, Brewster A, Singletary SE, Wei Q
Carcinogenesis. 2004
PubMed ID: 15090466
XPD polymorphism and risk of subsequent cancer in individuals with nonmelanoma skin cancer.
Brewster AM, Alberg AJ, Strickland PT, Hoffman SC, Helzlsouer K
Cancer Epidemiol Biomarkers Prev. 2004
PubMed ID: 15298945
Single nucleotide polymorphisms and outcome in docetaxel-cisplatin-treated advanced non-small-cell lung cancer.
Isla D, Sarries C, Rosell R, Alonso G, Domine M, Taron M, Lopez-Vivanco G, Camps C, Botia M, Nuñez L, Sanchez-Ronco M, Sanchez JJ, Lopez-Brea M, Barneto I, Paredes A, Medina B, Artal A, Lianes P
Ann Oncol. 2004
PubMed ID: 15277258
A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer.
Stoehlmacher J, Park DJ, Zhang W, Yang D, Groshen S, Zahedy S, Lenz HJ
Br J Cancer. 2004
PubMed ID: 15213713
Associations between XRCC1 and ERCC2 polymorphisms and DNA damage in peripheral blood lymphocyte among coke oven workers.
Leng S, Cheng J, Pan Z, Huang C, Niu Y, Dai Y, Li B, He F, Zheng Y
Biomarkers. 2004
PubMed ID: 15764301
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A.
Giglia-Mari G, Coin F, Ranish JA, Hoogstraten D, Theil A, Wijgers N, Jaspers NG, Raams A, Argentini M, van der Spek PJ, Botta E, Stefanini M, Egly JM, Aebersold R, Hoeijmakers JH, Vermeulen W
Nat Genet. 2004
PubMed ID: 15220921
XPD and XRCC1 genetic polymorphisms are prognostic factors in advanced non-small-cell lung cancer patients treated with platinum chemotherapy.
Gurubhagavatula S, Liu G, Park S, Zhou W, Su L, Wain JC, Lynch TJ, Neuberg DS, Christiani DC
J Clin Oncol. 2004
PubMed ID: 15173214
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.
Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW
Nat Biotechnol. 2004
PubMed ID: 15146197
Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy.
Ryu JS, Hong YC, Han HS, Lee JE, Kim S, Park YM, Kim YC, Hwang TS
Lung Cancer. 2004
PubMed ID: 15140544
High-throughput association testing on DNA pools to identify genetic variants that confer susceptibility to acute myeloid leukemia.
Rollinson S, Allan JM, Law GR, Roddam PL, Smith MT, Skibola C, Smith AG, Forrest MS, Sibley K, Higuchi R, Germer S, Morgan GJ
Cancer Epidemiol Biomarkers Prev. 2004
PubMed ID: 15159312
Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA.
Vodicka P, Kumar R, Stetina R, Sanyal S, Soucek P, Haufroid V, Dusinska M, Kuricova M, Zamecnikova M, Musak L, Buchancova J, Norppa H, Hirvonen A, Vodickova L, Naccarati A, Matousu Z, Hemminki K
Carcinogenesis. 2004
PubMed ID: 14729591
Polymorphisms in DNA repair and metabolic genes in bladder cancer.
Sanyal S, Festa F, Sakano S, Zhang Z, Steineck G, Norming U, Wijkström H, Larsson P, Kumar R, Hemminki K
Carcinogenesis. 2004
PubMed ID: 14688016
The DNA sequence and biology of human chromosome 19.
Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM
Nature. 2004
PubMed ID: 15057824
TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.
Le May N, Dubaele S, Proietti De Santis L, Billecocq A, Bouloy M, Egly JM
Cell. 2004
PubMed ID: 14980221
XPD gene polymorphism and host characteristics in the association with cutaneous malignant melanoma risk.
Baccarelli A, Calista D, Minghetti P, Marinelli B, Albetti B, Tseng T, Hedayati M, Grossman L, Landi G, Struewing JP, Landi MT
Br J Cancer. 2004
PubMed ID: 14735199
Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer.
Harms C, Salama SA, Sierra-Torres CH, Cajas-Salazar N, Au WW
Environ Mol Mutagen. 2004
PubMed ID: 15199549
Effect of XPD/ERCC2 polymorphisms on chromosome aberration frequencies in smokers and on sensitivity to the mutagenic tobacco-specific nitrosamine NNK.
Affatato AA, Wolfe KJ, Lopez MS, Hallberg C, Ammenheuser MM, Abdel-Rahman SZ
Environ Mol Mutagen. 2004
PubMed ID: 15199548
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Effects of ALDH2 gene polymorphisms and alcohol-drinking behavior on micronuclei frequency in non-smokers.
Ishikawa H, Yamamoto H, Tian Y, Kawano M, Yamauchi T, Yokoyama K
Mutat Res. 2003
PubMed ID: 14568296
Polymorphisms of the DNA repair genes XRCC1, XRCC3, XPD, interaction with environmental exposures, and bladder cancer risk in a case-control study in northern Italy.
Shen M, Hung RJ, Brennan P, Malaveille C, Donato F, Placidi D, Carta A, Hautefeuille A, Boffetta P, Porru S
Cancer Epidemiol Biomarkers Prev. 2003
PubMed ID: 14652287
The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA.
Zhou M, Deng L, Kashanchi F, Brady JN, Shatkin AJ, Kumar A
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14569024
Influence of genetic markers on survival in non-small cell lung cancer.
Rosell R, Taron M, Camps C, López-Vivanco G
Drugs Today (Barc). 2003
PubMed ID: 14668933
Association of the DNA repair gene XPD Asp312Asn polymorphism with p53 gene mutations in tobacco-related non-small cell lung cancer.
Gao WM, Romkes M, Day RD, Siegfried JM, Luketich JD, Mady HH, Melhem MF, Keohavong P
Carcinogenesis. 2003
PubMed ID: 12844488
Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
Xing D, Tan W, Lin D
Oncol Rep. 2003
PubMed ID: 12883749
Lack of involvement of nucleotide excision repair gene polymorphisms in colorectal cancer.
Mort R, Mo L, McEwan C, Melton DW
Br J Cancer. 2003
PubMed ID: 12865926
DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosis.
Ahsan H, Chen Y, Wang Q, Slavkovich V, Graziano JH, Santella RM
Toxicol Lett. 2003
PubMed ID: 12749816
Sequence variations in the DNA repair gene XPD and risk of lung cancer in a Chinese population.
Liang G, Xing D, Miao X, Tan W, Yu C, Lu W, Lin D
Int J Cancer. 2003
PubMed ID: 12740916
Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients.
Dubaele S, Proietti De Santis L, Bienstock RJ, Keriel A, Stefanini M, Van Houten B, Egly JM
Mol Cell. 2003
PubMed ID: 12820975
Rrn3 becomes inactivated in the process of ribosomal DNA transcription.
Hirschler-Laszkiewicz I, Cavanaugh AH, Mirza A, Lun M, Hu Q, Smink T, Rothblum LI
J Biol Chem. 2003
PubMed ID: 12646563
Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk.
Zhou W, Liu G, Miller DP, Thurston SW, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC
Cancer Epidemiol Biomarkers Prev. 2003
PubMed ID: 12692111
Structural and functional characterization of the human DNA repair helicase XPD by comparative molecular modeling and site-directed mutagenesis of the bacterial repair protein UvrB.
Bienstock RJ, Skorvaga M, Mandavilli BS, Van Houten B
J Biol Chem. 2003
PubMed ID: 12458209
Twelve single nucleotide polymorphisms on chromosome 19q13.2-13.3: linkage disequilibria and associations with basal cell carcinoma in Danish psoriatic patients.
Yin J, Vogel U, Gerdes LU, Dybdahl M, Bolund L, Nexø BA
Biochem Genet. 2003
PubMed ID: 12645871
[Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing]
Xing DY, Qi J, Tan W, Miao XP, Liang G, Yu CY, Lu WF, Zhou CN, Wu M, Lin DX
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003
PubMed ID: 12579497
Variable continental distribution of polymorphisms in the coding regions of DNA-repair genes.
Mathonnet G, Labuda D, Meloche C, Wambach T, Krajinovic M, Sinnett D
J Hum Genet. 2003
PubMed ID: 14625810
Assessment of nucleotide excision repair XPD polymorphisms in the peripheral blood of gemcitabine/cisplatin-treated advanced non-small-cell lung cancer patients.
Camps C, Sarries C, Roig B, Sanchez JJ, Queralt C, Sancho E, Martinez N, Tarón M, Rosell R
Clin Lung Cancer. 2003
PubMed ID: 14624713
Influence of common XPD and XRCC1 variant alleles on p53 mutations in lung tumors.
Hou SM, Ryk C, Kannio A, Angelini S, Fält S, Nyberg F, Husgafvel-Pursiainen K
Environ Mol Mutagen. 2003
PubMed ID: 12552590
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia.
Seedhouse C, Bainton R, Lewis M, Harding A, Russell N, Das-Gupta E
Blood. 2002
PubMed ID: 12393447
ERCC2/XPD gene polymorphisms and cancer risk.
Benhamou S, Sarasin A
Mutagenesis. 2002
PubMed ID: 12435843
Polymorphisms of the DNA repair gene XPD and risk of lung cancer in a Chinese population.
Xing D, Tan W, Wei Q, Lin D
Lung Cancer. 2002
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Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells.
Weber CA, Salazar EP, Stewart SA, Thompson LH
Mol Cell Biol. 1988
PubMed ID: 2835663
ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.
Conaway RC, Conaway JW
J Biol Chem. 1988
PubMed ID: 2449431
The physicochemical properties of hair in the BIDS syndrome.
Baden HP, Jackson CE, Weiss L, Jimbow K, Lee L, Kubilus J, Gold RJ
Am J Hum Genet. 1976
PubMed ID: 984047

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	2068	13871	N/A
EnsEMBL Gene(s)	ENSG00000104884	ENSMUSG00000030400	N/A
Unigene	Hs.487294	Mm.36524	N/A
Homologene	ERCC2	Ercc2	N/A
OMIM	126340	N/A	N/A
GeneCards	ERCC2	N/A	N/A
Beta Cell Genomics	DT.100023942 DT.102832553 DT.409967 DT.91655947	DT.101293170 DT.531316	N/A
Reactome	P18074	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	2068	13871	N/A

External resources from NIDDK Consortium Interconnectivity Network Top Help

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