T1DBase - A Bioinformatics Resource for Type 1 Diabetes Researchers

Gene Description:

eukaryotic translation initiation factor 2C, 4

Synonyms:

AGO4, EIF2C4, Eif2c4, Ago4, 5730550L01Rik, AI481660

Orthologs:

Human EIF2C4 (protein-coding), Mouse Eif2c4 (protein-coding), Rat Eif2c4 (protein-coding)

Sources

Regions Overlapping this Feature: Mouse: 1

Linkage Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd11	Mouse	chr4:125017654..132983386	7.97	148	4 no lod score

(Human) GRCh37 - chr1:36273773..36323491 (49.72 kb) View in Genome Browser

(Mouse) NCBIM37 - chr4:126166785..126210716 (43.93 kb) View in Genome Browser

(Rat) RGSC3.4 - chr5:145857594..145902950 (45.36 kb) View in Genome Browser

HaemAtlas Expression Table for EIF2C4:

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas
			no data					no data	no data	no data	no data	no data

Expression Legend

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Table for EIF2C4:

View all

KEGG Network: None available

Biocarta: 1

Reactome: 2

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 10

Publications: 33

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA
PLoS One. 2011
PubMed ID: 21731673
Argonaute proteins at a glance.
Ender C, Meister G
J Cell Sci. 2010
PubMed ID: 20484662
Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.
Michon F, Tummers M, Kyyrönen M, Frilander MJ, Thesleff I
Dev Biol. 2010
PubMed ID: 20102707
Argonaute proteins: potential biomarkers for human colon cancer.
Li L, Yu C, Gao H, Li Y
BMC Cancer. 2010
PubMed ID: 20146808
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
Chi SW, Zang JB, Mele A, Darnell RB
Nature. 2009
PubMed ID: 19536157
Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.
Potenza N, Papa U, Russo A
Cell Biol Int. 2009
PubMed ID: 19393748
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.
Weinmann L, Höck J, Ivacevic T, Ohrt T, Mütze J, Schwille P, Kremmer E, Benes V, Urlaub H, Meister G
Cell. 2009
PubMed ID: 19167051
Essential and overlapping functions for mammalian Argonautes in microRNA silencing.
Su H, Trombly MI, Chen J, Wang X
Genes Dev. 2009
PubMed ID: 19174539
Importance of translation and nonnucleolytic ago proteins for on-target RNA interference.
Wu L, Fan J, Belasco JG
Curr Biol. 2008
PubMed ID: 18771919
Capped small RNAs and MOV10 in human hepatitis delta virus replication.
Haussecker D, Cao D, Huang Y, Parameswaran P, Fire AZ, Kay MA
Nat Struct Mol Biol. 2008
PubMed ID: 18552826
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Inhibition of translational initiation by Let-7 MicroRNA in human cells.
Pillai RS, Bhattacharyya SN, Artus CG, Zoller T, Cougot N, Basyuk E, Bertrand E, Filipowicz W
Science. 2005
PubMed ID: 16081698
Differential expression of components of the microRNA machinery during mouse organogenesis.
Lü J, Qian J, Chen F, Tang X, Li C, Cardoso WV
Biochem Biophys Res Commun. 2005
PubMed ID: 16036130
Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.
Tao WA, Wollscheid B, O'Brien R, Eng JK, Li XJ, Bodenmiller B, Watts JD, Hood L, Aebersold R
Nat Methods. 2005
PubMed ID: 16094384
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA
BMC Dev Biol. 2005
PubMed ID: 16033648
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.
Pillai RS, Artus CG, Filipowicz W
RNA. 2004
PubMed ID: 15337849
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T
Mol Cell. 2004
PubMed ID: 15260970
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Identification of eight members of the Argonaute family in the human genome small star, filled.
Sasaki T, Shiohama A, Minoshima S, Shimizu N
Genomics. 2003
PubMed ID: 12906857
Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Nagase T, Ohara O, Koga H
DNA Res. 2003
PubMed ID: 14621295
Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K
Curr Biol. 2003
PubMed ID: 12526743
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.
Carmell MA, Xuan Z, Zhang MQ, Hannon GJ
Genes Dev. 2002
PubMed ID: 12414724
Creation of genome-wide protein expression libraries using random activation of gene expression.
Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S, Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L, Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N, Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J, Ducar M
Nat Biotechnol. 2001
PubMed ID: 11329013
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O
DNA Res. 2000
PubMed ID: 10997877
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636

Model Organism Phenotype Links

	Human	Mouse	Rat
Entrez Gene	192670	76850	298533
EnsEMBL Gene(s)	ENSG00000134698	ENSMUSG00000042500	ENSRNOG00000025596
Unigene	Hs.731451	Mm.86705	Rn.134659
Homologene	EIF2C4	Eif2c4	Eif2c4
OMIM	607356	N/A	N/A
GeneCards	EIF2C4	N/A	N/A
Beta Cell Genomics	DT.305156	DT.101725069 DT.94152413	N/A
Reactome	Q9HCK5	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	192670	76850	298533

Relevant resources:

Interactor	Interactor	Sources	Classification	Pubmed IDs
EIF2C4	SLC25A13	IntAct, BioGRID	empirical	19167051
EIF2C4	DNAJA2	IntAct, BioGRID	empirical	19167051
EIF2C4	TUBB4B	IntAct, BioGRID	empirical	19167051
EIF2C4	PRMT5	IntAct, BioGRID	empirical	19167051
EIF2C4	CDIPT	IntAct	empirical	19167051
EIF2C4	IPO8	IntAct, BioGRID	empirical	19167051
EIF2C4	IGF2BP1	IntAct	empirical	19167051
EIF2C4	PTGES3	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL35	IntAct, BioGRID	empirical	19167051
EIF2C4	SNRPD2P1	BioGRID	empirical	19167051
EIF2C4	SLC25A10	IntAct, BioGRID	empirical	19167051
EIF2C4	DBT	IntAct, BioGRID	empirical	19167051
EIF2C4	EEF1A1	IntAct	empirical	19167051
EIF2C4	PGAM5	IntAct, BioGRID	empirical	19167051
EIF2C4	EIF2C3	IntAct, BioGRID	empirical	19167051
EIF2C4	EIF2C4	BioGRID	empirical	19167051
EIF2C4	EEF1G	IntAct, BioGRID	empirical	19167051
EIF2C4	EIF4B	IntAct, BioGRID	empirical	19167051
EIF2C4	EMD	IntAct, BioGRID	empirical	19167051
EIF2C4	TUBB	IntAct	empirical	19167051
EIF2C4	CCT5	IntAct, BioGRID	empirical	19167051
EIF2C4	TNRC6B	IntAct, BioGRID	empirical	19167051
EIF2C4	DICER1	Reactome	predicted	12411505 11201747 16357216 16142218 11452083 12411504 18178619 15973356
EIF2C4	GALK1	IntAct, BioGRID	empirical	19167051
EIF2C4	MYCBP	IntAct, BioGRID	empirical	19167051
EIF2C4	PABPC1	IntAct	empirical	19167051
EIF2C4	EIF2C2	IntAct, BioGRID	empirical	19167051
EIF2C4	TNRC6A	IntAct, BioGRID	empirical	19167051
EIF2C4	SLC25A5	IntAct, BioGRID	empirical	19167051
EIF2C4	HNRNPC	IntAct	empirical	19167051
EIF2C4	DNAJA1	IntAct, BioGRID	empirical	19167051
EIF2C4	HSPA5	IntAct, BioGRID	empirical	19167051
EIF2C4	HSPA8	IntAct, BioGRID	empirical	19167051
EIF2C4	HSP90AA1	IntAct, BioGRID	empirical	19167051
EIF2C4	HSP90AB1	IntAct, BioGRID	empirical	19167051
EIF2C4	HIN1L	IntAct, BioGRID	empirical	19167051
EIF2C4	JAK1	IntAct, BioGRID	empirical	19167051
EIF2C4	ARF4	IntAct, BioGRID	empirical	19167051
EIF2C4	LOC390937	BioGRID	empirical	19167051
EIF2C4	YBX1	IntAct, BioGRID	empirical	19167051
EIF2C4	PRDX1	IntAct	empirical	19167051
EIF2C4	ATP5C1	IntAct, BioGRID	empirical	19167051
EIF2C4	DNAJB11	IntAct, BioGRID	empirical	19167051
EIF2C4	ATP5I	IntAct, BioGRID	empirical	19167051
EIF2C4	SLC25A3	IntAct, BioGRID	empirical	19167051
EIF2C4	QPCTL	IntAct	empirical	19167051
EIF2C4	AGK	IntAct, BioGRID	empirical	19167051
EIF2C4	PTS	IntAct, BioGRID	empirical	19167051
EIF2C4	ACTB	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL8	IntAct	empirical	19167051
EIF2C4	RPL11	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL12	IntAct	empirical	19167051
EIF2C4	RPL24	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL27	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL27A	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL38	IntAct, BioGRID	empirical	19167051
EIF2C4	RPS3A	IntAct	empirical	19167051
EIF2C4	RPS5	IntAct, BioGRID	empirical	19167051
EIF2C4	RPS9	IntAct, BioGRID	empirical	19167051
EIF2C4	RPS12	IntAct	empirical	19167051
EIF2C4	RPS18	IntAct, BioGRID	empirical	19167051
EIF2C4	RPS25	IntAct	empirical	19167051
EIF2C4	RPS26	IntAct, BioGRID	empirical	19167051
EIF2C4	SLC25A1	IntAct	empirical	19167051
EIF2C4	SNRPD2	IntAct	empirical	19167051
EIF2C4	TRIM21	IntAct, BioGRID	empirical	19167051
EIF2C4	SSBP1	IntAct, BioGRID	empirical	19167051
EIF2C4	TARBP2	Reactome	predicted	12411505 11201747 16357216 16142218 11452083 12411504 18178619 15973356
EIF2C4	TUFM	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL12P1	BioGRID	empirical	19167051
EIF2C4	UBC	BioGRID	empirical	21906983
EIF2C4	TUBA1A	IntAct	empirical	19167051
EIF2C4	WDR77	IntAct, BioGRID	empirical	19167051
EIF2C4	SLC25A22	IntAct, BioGRID	empirical	19167051
EIF2C4	RBM10	IntAct	empirical	19167051
EIF2C4	PABPC4	IntAct, BioGRID	empirical	19167051
EIF2C4	SUCLA2	IntAct, BioGRID	empirical	19167051
EIF2C4	RPS10P5	IntAct, BioGRID	empirical	19167051
EIF2C4	RPL23	IntAct, BioGRID	empirical	19167051