Home LPAR1
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(Human) GRCh37 - chr9:113635543..113801526 (165.98 kb) View in Genome Browser
(Mouse) NCBIM37 - chr4:58448124..58566770 (118.65 kb) View in Genome Browser
(Rat) RGSC3.4 - chr5:76449470..76571458 (121.99 kb) View in Genome Browser
HaemAtlas Expression Table for LPAR1:|
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
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| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for LPAR1:The LPAR1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| LPAR1 | ARHGEF12 | HPRD, MINT | empirical | 15755723 |
| LPAR1 | GNAI3 | HPRD | empirical | 9600933 |
| LPAR1 | KRAS | IntAct | empirical | 21988832 |
| LPAR1 | SLC9A3R2 | HPRD | empirical | 16203867 |
| LPAR1 | ARHGEF11 | HPRD, MINT | empirical | 15755723 |
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Publications: 143
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Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish.
Yukiura H, Hama K, Nakanaga K, Tanaka M, Asaoka Y, Okudaira S, Arima N, Inoue A, Hashimoto T, Arai H, Kawahara A, Nishina H, Aoki J
J Biol Chem. 2011
PubMed ID: 21971049
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LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells.
Kim JH, Adelstein RS
J Cell Physiol. 2011
PubMed ID: 21302283
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Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.
Zhao J, He D, Su Y, Berdyshev E, Chun J, Natarajan V, Zhao Y
Am J Physiol Lung Cell Mol Physiol. 2011
PubMed ID: 21821728
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p2y5/LPA(6) attenuates LPA(1)-mediated VE-cadherin translocation and cell-cell dissociation through G(12/13) protein-Src-Rap1.
Kimura T, Mogi C, Sato K, Tomura H, Ohta H, Im DS, Kuwabara A, Kurose H, Murakami M, Okajima F
Cardiovasc Res. 2011
PubMed ID: 21632882
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Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling.
Herr KJ, Herr DR, Lee CW, Noguchi K, Chun J
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21878565
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Lysophosphatidic acid signaling may initiate fetal hydrocephalus.
Yung YC, Mutoh T, Lin ME, Noguchi K, Rivera RR, Choi JW, Kingsbury MA, Chun J
Sci Transl Med. 2011
PubMed ID: 21900594
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Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass.
Gennero I, Laurencin-Dalicieux S, Conte-Auriol F, Briand-Mésange F, Laurencin D, Rue J, Beton N, Malet N, Mus M, Tokumura A, Bourin P, Vico L, Brunel G, Oreffo RO, Chun J, Salles JP
Bone. 2011
PubMed ID: 21569876
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Abnormalities in α/β-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice.
Musazzi L, Di Daniel E, Maycox P, Racagni G, Popoli M
Int J Neuropsychopharmacol. 2011
PubMed ID: 20942999
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TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J Lipid Res. 2011
PubMed ID: 21521824
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A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
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Modulation of LPA receptor expression in the human brain following neurotrauma.
Frugier T, Crombie D, Conquest A, Tjhong F, Taylor C, Kulkarni T, McLean C, Pébay A
Cell Mol Neurobiol. 2011
PubMed ID: 21234797
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Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development.
López-Juárez A, Morales-Lázaro S, Sánchez-Sánchez R, Sunkara M, Lomelí H, Velasco I, Morris AJ, Escalante-Alcalde D
Glia. 2011
PubMed ID: 21319224
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Unmasking of LPA1 receptor-mediated migration response to lysophosphatidic acid by interleukin-1β-induced attenuation of Rho signaling pathways in rat astrocytes.
Sato K, Horiuchi Y, Jin Y, Malchinkhuu E, Komachi M, Kondo T, Okajima F
J Neurochem. 2011
PubMed ID: 21244430
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Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice.
Castilla-Ortega E, Hoyo-Becerra C, Pedraza C, Chun J, Rodríguez De Fonseca F, Estivill-Torrús G, Santín LJ
PLoS One. 2011
PubMed ID: 21980482
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Mesenchymal stem cells stimulate angiogenesis in a murine xenograft model of A549 human adenocarcinoma through an LPA1 receptor-dependent mechanism.
Jeon ES, Lee IH, Heo SC, Shin SH, Choi YJ, Park JH, Park do Y, Kim JH
Biochim Biophys Acta. 2010
PubMed ID: 20708100
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Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.
Itoh R, Miura S, Takimoto A, Kondo S, Sano H, Hiraki Y
J Bone Miner Metab. 2010
PubMed ID: 20458606
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Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
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Differential involvement of caveolin-1 in brown adipocyte signaling: impaired beta3-adrenergic, but unaffected LPA, PDGF and EGF receptor signaling.
Mattsson CL, Andersson ER, Nedergaard J
Biochim Biophys Acta. 2010
PubMed ID: 20381543
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The sensitization of peripheral C-fibers to lysophosphatidic acid in bone cancer pain.
Zhao J, Pan HL, Li TT, Zhang YQ, Wei JY, Zhao ZQ
Life Sci. 2010
PubMed ID: 20553953
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Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation.
Subramanian P, Karshovska E, Reinhard P, Megens RT, Zhou Z, Akhtar S, Schumann U, Li X, van Zandvoort M, Ludin C, Weber C, Schober A
Circ Res. 2010
PubMed ID: 20360252
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LPA receptor expression in the central nervous system in health and following injury.
Goldshmit Y, Munro K, Leong SY, Pébay A, Turnley AM
Cell Tissue Res. 2010
PubMed ID: 20495828
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Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor.
Castilla-Ortega E, Sánchez-López J, Hoyo-Becerra C, Matas-Rico E, Zambrana-Infantes E, Chun J, De Fonseca FR, Pedraza C, Estivill-Torrús G, Santin LJ
Neurobiol Learn Mem. 2010
PubMed ID: 20388543
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The role of lysophosphatidic acid receptors in phenotypic modulation of vascular smooth muscle cells.
Zhou Z, Niu J, Zhang Z
Mol Biol Rep. 2010
PubMed ID: 19757175
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Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis.
Dubin AE, Herr DR, Chun J
J Neurosci. 2010
PubMed ID: 20505096
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Mutations of lysophosphatidic acid receptor genes in human osteosarcoma cells.
Okabe K, Hayashi M, Fujii M, Honoki K, Mori T, Fukushima N, Tsujiuchi T
Pathobiology. 2010
PubMed ID: 21116120
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Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine.
Nagai J, Uchida H, Matsushita Y, Yano R, Ueda M, Niwa M, Aoki J, Chun J, Ueda H
Mol Pain. 2010
PubMed ID: 21062487
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Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.
Kariuki SN, Franek BS, Kumar AA, Arrington J, Mikolaitis RA, Utset TO, Jolly M, Crow MK, Skol AD, Niewold TB
Arthritis Res Ther. 2010
PubMed ID: 20659327
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Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.
Bernhart E, Kollroser M, Rechberger G, Reicher H, Heinemann A, Schratl P, Hallström S, Wintersperger A, Nusshold C, DeVaney T, Zorn-Pauly K, Malli R, Graier W, Malle E, Sattler W
Proteomics. 2010
PubMed ID: 19899077
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Altered food consumption in mice lacking lysophosphatidic acid receptor-1.
Dusaulcy R, Daviaud D, Pradère JP, Grès S, Valet P, Saulnier-Blache JS
J Physiol Biochem. 2009
PubMed ID: 20358347
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Lysophosphatidic acid receptor expression in chronic lymphocytic leukemia leads to cell survival mediated though vascular endothelial growth factor expression.
Kumar SA, Hu X, Brown M, Kuschak B, Hernandez TA, Johnston JB, Gibson SB
Leuk Lymphoma. 2009
PubMed ID: 19860625
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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
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Sequence variants in three loci influence monocyte counts and erythrocyte volume.
Ferreira MA, Hottenga JJ, Warrington NM, Medland SE, Willemsen G, Lawrence RW, Gordon S, de Geus EJ, Henders AK, Smit JH, Campbell MJ, Wallace L, Evans DM, Wright MJ, Nyholt DR, James AL, Beilby JP, Penninx BW, Palmer LJ, Frazer IH, Montgomery GW, Martin NG, Boomsma DI
Am J Hum Genet. 2009
PubMed ID: 19853236
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Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits.
Santin LJ, Bilbao A, Pedraza C, Matas-Rico E, López-Barroso D, Castilla-Ortega E, Sánchez-López J, Riquelme R, Varela-Nieto I, de la Villa P, Suardíaz M, Chun J, De Fonseca FR, Estivill-Torrús G
Genes Brain Behav. 2009
PubMed ID: 19689455
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Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.
Aziziyeh AI, Li TT, Pape C, Pampillo M, Chidiac P, Possmayer F, Babwah AV, Bhattacharya M
Cell Signal. 2009
PubMed ID: 19306925
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Receptor-mediated vascular smooth muscle migration induced by LPA involves p38 mitogen-activated protein kinase pathway activation.
Zhou ZB, Niu JP, Zhang ZJ
Int J Mol Sci. 2009
PubMed ID: 19742132
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Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect.
E S, Lai YJ, Tsukahara R, Chen CS, Fujiwara Y, Yue J, Yu JH, Guo H, Kihara A, Tigyi G, Lin FT
J Biol Chem. 2009
PubMed ID: 19293149
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Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
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The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration.
Yang C, Lafleur J, Mwaikambo BR, Zhu T, Gagnon C, Chemtob S, Di Polo A, Hardy P
Invest Ophthalmol Vis Sci. 2009
PubMed ID: 18978343
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Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia.
Zeng Y, Kakehi Y, Nouh MA, Tsunemori H, Sugimoto M, Wu XX
Prostate. 2009
PubMed ID: 19025891
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Mutations of lysophosphatidic acid receptor-1 gene during progression of lung tumors in rats.
Yamada T, Obo Y, Furukawa M, Hotta M, Yamasaki A, Honoki K, Fukushima N, Tsujiuchi T
Biochem Biophys Res Commun. 2009
PubMed ID: 19026987
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Frequent mutations of lysophosphatidic acid receptor-1 gene in rat liver tumors.
Obo Y, Yamada T, Furukawa M, Hotta M, Honoki K, Fukushima N, Tsujiuchi T
Mutat Res. 2009
PubMed ID: 19000703
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Lysophosphatidic acid stimulates cell growth by different mechanisms in SKOV-3 and Caov-3 ovarian cancer cells: distinct roles for Gi- and Rho-dependent pathways.
Hurst JH, Hooks SB
Pharmacology. 2009
PubMed ID: 19420982
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In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.
Taghavi P, Verhoeven E, Jacobs JJ, Lambooij JP, Stortelers C, Tanger E, Moolenaar WH, van Lohuizen M
Oncogene. 2008
PubMed ID: 18762810
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Expression patterns of the lysophospholipid receptor genes during mouse early development.
Ohuchi H, Hamada A, Matsuda H, Takagi A, Tanaka M, Aoki J, Arai H, Noji S
Dev Dyn. 2008
PubMed ID: 18924241
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Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus.
Matas-Rico E, García-Diaz B, Llebrez-Zayas P, López-Barroso D, Santín L, Pedraza C, Smith-Fernández A, Fernández-Llebrez P, Tellez T, Redondo M, Chun J, De Fonseca FR, Estivill-Torrús G
Mol Cell Neurosci. 2008
PubMed ID: 18708146
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Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-kappaB-dependent pathway: a possible role in angiogenesis of endometrium and placenta.
Chen SU, Lee H, Chang DY, Chou CH, Chang CY, Chao KH, Lin CW, Yang YS
Endocrinology. 2008
PubMed ID: 18617617
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
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Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA(1/3), COX-2, and NF-kappaB activation- and EGFR transactivation-dependent mechanisms.
Lin CI, Chen CN, Huang MT, Lee SJ, Lin CH, Chang CC, Lee H
Cell Signal. 2008
PubMed ID: 18627789
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Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure.
Panchatcharam M, Miriyala S, Yang F, Rojas M, End C, Vallant C, Dong A, Lynch K, Chun J, Morris AJ, Smyth SS
Circ Res. 2008
PubMed ID: 18703779
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Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.
Yamada T, Yano S, Ogino H, Ikuta K, Kakiuchi S, Hanibuchi M, Kanematsu T, Taniguchi T, Sekido Y, Sone S
Cancer Sci. 2008
PubMed ID: 18754873
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Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling.
Ye X, Skinner MK, Kennedy G, Chun J
Biol Reprod. 2008
PubMed ID: 18448840
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Testing the druggable EDG2 knee OA genetic factor for replication in a wide range of sample collections.
Dieguez-Gonzalez R, Calaza M, Shi D, Meulenbelt I, Loughlin J, Tsezou A, Dai J, Malizos KN, Slagboom EP, Kloppenburg M, Chapman K, Jiang Q, Kremer D, Gomez-Reino JJ, Nakajima N, Ikegawa S, Gonzalez A
Ann Rheum Dis. 2008
PubMed ID: 18625619
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A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
Mototani H, Iida A, Nakajima M, Furuichi T, Miyamoto Y, Tsunoda T, Sudo A, Kotani A, Uchida A, Ozaki K, Tanaka Y, Nakamura Y, Tanaka T, Notoya K, Ikegawa S
Hum Mol Genet. 2008
PubMed ID: 18325907
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Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cells.
Hasegawa Y, Murph M, Yu S, Tigyi G, Mills GB
Mol Oncol. 2008
PubMed ID: 19081821
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A lysophosphatidic acid receptor lacking the PDZ-binding domain is constitutively active and stimulates cell proliferation.
Shano S, Hatanaka K, Ninose S, Moriyama R, Tsujiuchi T, Fukushima N
Biochim Biophys Acta. 2008
PubMed ID: 18157949
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GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
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Absence of LPA1 signaling results in defective cortical development.
Estivill-Torrús G, Llebrez-Zayas P, Matas-Rico E, Santín L, Pedraza C, De Diego I, Del Arco I, Fernández-Llebrez P, Chun J, De Fonseca FR
Cereb Cortex. 2008
PubMed ID: 17656621
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Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid.
Inoue M, Xie W, Matsushita Y, Chun J, Aoki J, Ueda H
Neuroscience. 2008
PubMed ID: 18280050
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Different mechanisms regulate lysophosphatidic acid (LPA)-dependent versus phorbol ester-dependent internalization of the LPA1 receptor.
Urs NM, Kowalczyk AP, Radhakrishna H
J Biol Chem. 2008
PubMed ID: 18089565
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Regulation of LPA receptor function by estrogens.
González-Arenas A, Avendaño-Vázquez SE, Cabrera-Wrooman A, Tapia-Carrillo D, Larrea F, García-Becerra R, García-Sáinz JA
Biochim Biophys Acta. 2008
PubMed ID: 18166159
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Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?
Zhao C, Fernandes MJ, Prestwich GD, Turgeon M, Di Battista J, Clair T, Poubelle PE, Bourgoin SG
Mol Pharmacol. 2008
PubMed ID: 18006645
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Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H
BMC Genomics. 2008
PubMed ID: 18973680
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Involvement of LPA1 receptor signaling in the reorganization of spinal input through Abeta-fibers in mice with partial sciatic nerve injury.
Xie W, Matsumoto M, Chun J, Ueda H
Mol Pain. 2008
PubMed ID: 18854053
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Dissociation of heterotrimeric g proteins in cells.
Lambert NA
Sci Signal. 2008
PubMed ID: 18577758
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The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.
Tager AM, LaCamera P, Shea BS, Campanella GS, Selman M, Zhao Z, Polosukhin V, Wain J, Karimi-Shah BA, Kim ND, Hart WK, Pardo A, Blackwell TS, Xu Y, Chun J, Luster AD
Nat Med. 2008
PubMed ID: 18066075
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Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.
Horak CE, Mendoza A, Vega-Valle E, Albaugh M, Graff-Cherry C, McDermott WG, Hua E, Merino MJ, Steinberg SM, Khanna C, Steeg PS
Cancer Res. 2007
PubMed ID: 18089805
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LPA1 receptor activation promotes renal interstitial fibrosis.
Pradère JP, Klein J, Grès S, Guigné C, Neau E, Valet P, Calise D, Chun J, Bascands JL, Saulnier-Blache JS, Schanstra JP
J Am Soc Nephrol. 2007
PubMed ID: 18003779
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Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.
Lin CI, Chen CN, Lin PW, Chang KJ, Hsieh FJ, Lee H
Biochem Biophys Res Commun. 2007
PubMed ID: 17923111
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Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML, Meltzer PS, Steeg PS
Cancer Res. 2007
PubMed ID: 17671192
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Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha.
Hao F, Tan M, Xu X, Han J, Miller DD, Tigyi G, Cui MZ
Biochim Biophys Acta. 2007
PubMed ID: 17531530
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LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells.
Chen M, Towers LN, O'Connor KL
Am J Physiol Cell Physiol. 2007
PubMed ID: 17496233
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P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid.
Panupinthu N, Zhao L, Possmayer F, Ke HZ, Sims SM, Dixon SJ
J Biol Chem. 2007
PubMed ID: 17135244
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EDG receptors as a potential therapeutic target in retinal ischemia-reperfusion injury.
Savitz SI, Dhallu MS, Malhotra S, Mammis A, Ocava LC, Rosenbaum PS, Rosenbaum DM
Brain Res. 2006
PubMed ID: 17026968
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Involvement of aberrant DNA methylation on reduced expression of lysophosphatidic acid receptor-1 gene in rat tumor cell lines.
Tsujiuchi T, Shimizu K, Onishi M, Sugata E, Fujii H, Mori T, Honoki K, Fukushima N
Biochem Biophys Res Commun. 2006
PubMed ID: 16970915
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Expression and function of lysophosphatidic acid LPA1 receptor in prostate cancer cells.
Guo R, Kasbohm EA, Arora P, Sample CJ, Baban B, Sud N, Sivashanmugam P, Moniri NH, Daaka Y
Endocrinology. 2006
PubMed ID: 16809448
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Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to Gq.
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Cell Signal. 2006
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Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.
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J Biol Chem. 2006
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FEBS Lett. 2006
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Stable association between G alpha(q) and phospholipase C beta 1 in living cells.
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J Biol Chem. 2006
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Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA1) in mammalian cells.
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Biochem J. 2006
PubMed ID: 16716145
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Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.
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Mol Cell Biol. 2006
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The role of LPA1 in formation of synapses among cultured hippocampal neurons.
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J Neurochem. 2006
PubMed ID: 16638019
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
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PLoS Biol. 2006
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Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development.
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Dev Biol. 2006
PubMed ID: 16434032
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Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness.
Cunningham MO, Hunt J, Middleton S, LeBeau FE, Gillies MJ, Gillies MG, Davies CH, Maycox PR, Whittington MA, Racca C
J Neurosci. 2006
PubMed ID: 16525056
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Lysophosphatidic acid stimulates cell proliferation in rat chondrocytes.
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Biochem Pharmacol. 2005
PubMed ID: 16242672
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A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors.
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J Cell Sci. 2005
PubMed ID: 16263766
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Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
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Science. 2005
PubMed ID: 16141072
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Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs).
Yamada T, Ohoka Y, Kogo M, Inagaki S
J Biol Chem. 2005
PubMed ID: 15755723
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Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2.
Simon MF, Daviaud D, Pradère JP, Grès S, Guigné C, Wabitsch M, Chun J, Valet P, Saulnier-Blache JS
J Biol Chem. 2005
PubMed ID: 15710620
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Neurochemical changes in LPA1 receptor deficient mice--a putative model of schizophrenia.
Roberts C, Winter P, Shilliam CS, Hughes ZA, Langmead C, Maycox PR, Dawson LA
Neurochem Res. 2005
PubMed ID: 16018581
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Phosphorylation and desensitization of the lysophosphatidic acid receptor LPA1.
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Biochem J. 2005
PubMed ID: 15369458
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Cell density-dependent expression of EDG family receptors and mesangial cell proliferation: role in lysophosphatidic acid-mediated cell growth.
Xing Y, Ganji SH, Noh JW, Kamanna VS
Am J Physiol Renal Physiol. 2004
PubMed ID: 15292052
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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Genome Res. 2004
PubMed ID: 15489334
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The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor.
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FASEB J. 2004
PubMed ID: 15208267
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Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling.
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Nat Med. 2004
PubMed ID: 15195086
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DNA sequence and analysis of human chromosome 9.
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Nature. 2004
PubMed ID: 15164053
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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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Nature. 2004
PubMed ID: 15057822
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TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.
Xu J, Lai YJ, Lin WC, Lin FT
J Biol Chem. 2004
PubMed ID: 14688263
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
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LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease.
Harrison SM, Reavill C, Brown G, Brown JT, Cluderay JE, Crook B, Davies CH, Dawson LA, Grau E, Heidbreder C, Hemmati P, Hervieu G, Howarth A, Hughes ZA, Hunter AJ, Latcham J, Pickering S, Pugh P, Rogers DC, Shilliam CS, Maycox PR
Mol Cell Neurosci. 2003
PubMed ID: 14697676
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Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding.
Kingsbury MA, Rehen SK, Contos JJ, Higgins CM, Chun J
Nat Neurosci. 2003
PubMed ID: 14625558
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
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The Immunohistochemical expression of endothelial cell differentiation gene-2 receptor in human colorectal adenomas.
Komuro Y, Watanabe T, Kitayama J, Yamaguchi H, Tsuno N, Nagawa H
Hepatogastroenterology. 2003
PubMed ID: 14696401
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Modulation of pro-inflammatory gene expression by nuclear lysophosphatidic acid receptor type-1.
Gobeil F, Bernier SG, Vazquez-Tello A, Brault S, Beauchamp MH, Quiniou C, Marrache AM, Checchin D, Sennlaub F, Hou X, Nader M, Bkaily G, Ribeiro-da-Silva A, Goetzl EJ, Chemtob S
J Biol Chem. 2003
PubMed ID: 12847111
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A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting.
Bräuer AU, Savaskan NE, Kühn H, Prehn S, Ninnemann O, Nitsch R
Nat Neurosci. 2003
PubMed ID: 12730698
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Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S
Oncogene. 2003
PubMed ID: 12761501
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Agonist-induced endocytosis of lysophosphatidic acid-coupled LPA1/EDG-2 receptors via a dynamin2- and Rab5-dependent pathway.
Murph MM, Scaccia LA, Volpicelli LA, Radhakrishna H
J Cell Sci. 2003
PubMed ID: 12668728
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Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1.
Shida D, Kitayama J, Yamaguchi H, Okaji Y, Tsuno NH, Watanabe T, Takuwa Y, Nagawa H
Cancer Res. 2003
PubMed ID: 12670925
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Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, Moolenaar WH
J Biol Chem. 2003
PubMed ID: 12393875
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
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Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis.
McGiffert C, Contos JJ, Friedman B, Chun J
FEBS Lett. 2002
PubMed ID: 12401212
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Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).
Contos JJ, Ishii I, Fukushima N, Kingsbury MA, Ye X, Kawamura S, Brown JH, Chun J
Mol Cell Biol. 2002
PubMed ID: 12215548
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Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors.
Hama K, Bandoh K, Kakehi Y, Aoki J, Arai H
FEBS Lett. 2002
PubMed ID: 12123830
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Oligodendroglial expression of Edg-2 receptor: developmental analysis and pharmacological responses to lysophosphatidic acid.
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Mol Cell Neurosci. 2002
PubMed ID: 12139919
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Immunohistological localization of the myelinating cell-specific receptor LP(A1).
Cervera P, Tirard M, Barron S, Allard J, Trottier S, Lacombe J, Daumas-Duport C, Sokoloff P
Glia. 2002
PubMed ID: 11948806
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Genomic organization and chromosomal localization of the mouse IKBKAP gene.
Coli R, Anderson SL, Volpi SA, Rubin BY
Gene. 2001
PubMed ID: 11722848
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Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling.
Weiner JA, Fukushima N, Contos JJ, Scherer SS, Chun J
J Neurosci. 2001
PubMed ID: 11549717
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Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3.
Ishii I, Friedman B, Ye X, Kawamura S, McGiffert C, Contos JJ, Kingsbury MA, Zhang G, Brown JH, Chun J
J Biol Chem. 2001
PubMed ID: 11443127
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Two novel Xenopus homologs of mammalian LP(A1)/EDG-2 function as lysophosphatidic acid receptors in Xenopus oocytes and mammalian cells.
Kimura Y, Schmitt A, Fukushima N, Ishii I, Kimura H, Nebreda AR, Chun J
J Biol Chem. 2001
PubMed ID: 11278944
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The mouse lp(A3)/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern.
Contos JJ, Chun J
Gene. 2001
PubMed ID: 11313151
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Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
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Lysophosphatidic acid receptors.
Contos JJ, Ishii I, Chun J
Mol Pharmacol. 2000
PubMed ID: 11093753
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Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior.
Contos JJ, Fukushima N, Weiner JA, Kaushal D, Chun J
Proc Natl Acad Sci U S A. 2000
PubMed ID: 11087877
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RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
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Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
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Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
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Edg-2 in myelin-forming cells: isoforms, genomic mapping, and exclusion in Charcot-Marie-Tooth disease.
Allard J, Barron S, Trottier S, Cervera P, Daumas-Duport C, Leguern E, Brice A, Schwartz JC, Sokoloff P
Glia. 1999
PubMed ID: 10384882
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Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate.
Zhang G, Contos JJ, Weiner JA, Fukushima N, Chun J
Gene. 1999
PubMed ID: 9931453
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
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Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization.
An S, Bleu T, Zheng Y, Goetzl EJ
Mol Pharmacol. 1998
PubMed ID: 9804623
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Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain.
Weiner JA, Hecht JH, Chun J
J Comp Neurol. 1998
PubMed ID: 9717712
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Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, lpA1/vzg-1/Gpcr26.
Contos JJ, Chun J
Genomics. 1998
PubMed ID: 9721207
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A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid.
Fukushima N, Kimura Y, Chun J
Proc Natl Acad Sci U S A. 1998
PubMed ID: 9600933
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A rat G protein-coupled receptor selectively expressed in myelin-forming cells.
Allard J, Barrón S, Diaz J, Lubetzki C, Zalc B, Schwartz JC, Sokoloff P
Eur J Neurosci. 1998
PubMed ID: 9753172
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Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate.
An S, Goetzl EJ, Lee H
J Cell Biochem Suppl. 1998
PubMed ID: 9893266
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Lysophosphatidic acid: G-protein signalling and cellular responses.
Moolenaar WH, Kranenburg O, Postma FR, Zondag GC
Curr Opin Cell Biol. 1997
PubMed ID: 9069262
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Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
An S, Dickens MA, Bleu T, Hallmark OG, Goetzl EJ
Biochem Biophys Res Commun. 1997
PubMed ID: 9070858
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Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.
Macrae AD, Premont RT, Jaber M, Peterson AS, Lefkowitz RJ
Brain Res Mol Brain Res. 1996
PubMed ID: 9013780
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Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.
Hecht JH, Weiner JA, Post SR, Chun J
J Cell Biol. 1996
PubMed ID: 8922387
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Tissue-specific expression of novel messenger ribonucleic acids cloned from a renin-expressing kidney tumor cell line (As4.1).
Thompson HA, Burson JM, Lang JA, Gross KW, Sigmund CD
Endocrinology. 1995
PubMed ID: 7789330
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