Home AFP
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Regions Overlapping this Feature:
Rat: 1
Other Regions: 1 Available
Other Regions: 1 Available
| Locus | Species | Chromosomal Location | Mb | Number of genes |
|---|---|---|---|---|
| Iddm31 | Rat | chr14:4895894..19800418 | 14.90 | 140 |
(Human) GRCh37 - chr4:74296855..74321891 (254 kb) View in Genome Browser
(Mouse) NCBIM37 - chr5:90919740..90937933 (18.19 kb) View in Genome Browser
(Rat) RGSC3.4 - chr14:19092563..19110728 (18.16 kb) View in Genome Browser
HaemAtlas Expression Table for AFP:|
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
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Expression Legend
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for AFP:The AFP interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| AFP | STAMBP | IntAct, BioGRID | empirical | 19615732 |
| AFP | AP4S1 | IntAct | empirical | 21988832 |
| AFP | PHB2 | IntAct | empirical | 21988832 |
| AFP | CCR5 | HPRD, BioGRID | empirical | 12176010 |
| AFP | GNB1 | IntAct | empirical | 21988832 |
| AFP | EHD4 | IntAct | empirical | 21988832 |
| AFP | HLA-B | IntAct | empirical | 17353931 |
| AFP | PIDD | IntAct | empirical | 21988832 |
| AFP | PSMB7 | IntAct | empirical | 21988832 |
| AFP | MED27 | IntAct | empirical | 21988832 |
| AFP | SGSM2 | HPRD, MINT, IntAct, BioGRID | empirical | 16169070 |
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Type 1 Diabetes Publications: 1
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Identification of transcripts with enriched expression in the developing and adult pancreas.
Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones S, Marra MA, Helgason CD
Genome Biol. 2008
PubMed ID: 18554416
Publications: 379
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Downregulation of alpha-fetoprotein expression by LHX4: a critical role in hepatocarcinogenesis.
Hung TM, Hu RH, Ho CM, Chiu YL, Lee JL, Jeng YM, Shih DT, Lee PH
Carcinogenesis. 2011
PubMed ID: 21965270
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Elevated serum alpha fetoprotein levels promote pathological progression of hepatocellular carcinoma.
Li P, Wang SS, Liu H, Li N, McNutt MA, Li G, Ding HG
World J Gastroenterol. 2011
PubMed ID: 22147961
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α-Fetoprotein impairs activation of natural killer cells by inhibiting the function of dendritic cells.
Yamamoto M, Tatsumi T, Miyagi T, Tsunematsu H, Aketa H, Hosui A, Kanto T, Hiramatsu N, Hayashi N, Takehara T
Clin Exp Immunol. 2011
PubMed ID: 21592114
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Clinical significance of alpha-fetoprotein mRNA in peripheral blood in liver resection for hepatocellular carcinoma.
Marubashi S, Nagano H, Wada H, Kobayashi S, Eguchi H, Takeda Y, Tanemura M, Umeshita K, Doki Y, Mori M
Ann Surg Oncol. 2011
PubMed ID: 21301972
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α-fetoprotein involvement during glucocorticoid-induced precocious maturation in rat colon.
Chen M, Sun P, Liu XY, Dong D, Du J, Gu L, Ge YB
World J Gastroenterol. 2011
PubMed ID: 21734804
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The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes.
Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21670299
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A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
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Sequential morphological characteristics of murine fetal liver hematopoietic microenvironment in Swiss Webster mice.
Ayres-Silva Jde P, Manso PP, Madeira MR, Pelajo-Machado M, Lenzi HL
Cell Tissue Res. 2011
PubMed ID: 21541657
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Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas.
Xu CR, Cole PA, Meyers DJ, Kormish J, Dent S, Zaret KS
Science. 2011
PubMed ID: 21596989
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Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo.
Hudson QJ, Seidl CI, Kulinski TM, Huang R, Warczok KE, Bittner R, Bartolomei MS, Barlow DP
Dev Biol. 2011
PubMed ID: 21354127
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Maternal serum hCG, PAPP-A and AFP as predictors of hemoglobin Bart disease at mid-pregnancy.
Tongprasert F, Wanapirak C, Tongsong T
Prenat Diagn. 2011
PubMed ID: 21312197
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Lens culinaris agglutinin-reactive fraction of AFP is a useful prognostic biomarker for survival after repeat hepatic resection for HCC.
Matsuda M, Asakawa M, Amemiya H, Fujii H
J Gastroenterol Hepatol. 2011
PubMed ID: 21155886
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Clinical significance of the highly sensitive fucosylated fraction of α-fetoprotein in patients with chronic liver disease.
Hanaoka T, Sato S, Tobita H, Miyake T, Ishihara S, Akagi S, Amano Y, Kinoshita Y
J Gastroenterol Hepatol. 2011
PubMed ID: 21083609
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Epiplakin1 is expressed in the cholangiocyte lineage cells in normal liver and adult progenitor cells in injured liver.
Matsuo A, Yoshida T, Yasukawa T, Miki R, Kume K, Kume S
Gene Expr Patterns. 2011
PubMed ID: 21216305
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Early α-fetoprotein response as a predictor for clinical outcome after localized concurrent chemoradiotherapy for advanced hepatocellular carcinoma.
Kim BK, Ahn SH, Seong JS, Park JY, Kim do Y, Kim JK, Lee do Y, Lee KH, Han KH
Liver Int. 2011
PubMed ID: 21083802
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The mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesis.
Shibata M, García-García MJ
Dev Biol. 2011
PubMed ID: 21094155
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Unexpected role of α-fetoprotein in spermatogenesis.
Yazama F, Tai A
PLoS One. 2011
PubMed ID: 21573244
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Detection of α-fetoprotein and glypican-3 mRNAs in the peripheral blood of hepatocellular carcinoma patients by using multiple FQ-RT-PCR.
Yan D, He Q, Chen Y, Wang L, Zhang X
J Clin Lab Anal. 2011
PubMed ID: 21438004
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Maternal serum α-fetoprotein at 11-13 weeks' gestation in spontaneous early preterm delivery.
Beta J, Bredaki FE, Rodriguez Calvo J, Akolekar R, Nicolaides KH
Fetal Diagn Ther. 2011
PubMed ID: 21411977
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Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.
Pfister S, Jones VJ, Power M, Truisi GL, Khoo PL, Steiner KA, Kanai-Azuma M, Kanai Y, Tam PP, Loebel DA
Int J Dev Biol. 2011
PubMed ID: 21305474
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
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Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function.
Setiyono A, Budiyati AD, Purwantomo S, Anggelia MR, Fanany I, Wibowo GA, Bachtiar I, Utama A, Tai S
BMC Immunol. 2011
PubMed ID: 21235824
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A hypoxia- and {alpha}-fetoprotein-dependent oncolytic adenovirus exhibits specific killing of hepatocellular carcinomas.
Kwon OJ, Kim PH, Huyn S, Wu L, Kim M, Yun CO
Clin Cancer Res. 2010
PubMed ID: 21169258
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Immunohistochemical localization of cytokeratins in the junctional region of ectoderm and endoderm.
Hosoya A, Kwak S, Kim EJ, Lunny DP, Lane EB, Cho SW, Jung HS
Anat Rec (Hoboken). 2010
PubMed ID: 20818615
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[Effects of alpha-fetoprotein on the expression of TRAIL death receptor-2 and its role on resisting the cytotoxicity of TRAIL in hepatoma cells].
Lin YS, Zhu MY, Zhou S, Xie XJ, Li MS
Zhonghua Gan Zang Bing Za Zhi. 2010
PubMed ID: 21059290
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AFP computational secreted network construction and analysis between human hepatocellular carcinoma (HCC) and no-tumor hepatitis/cirrhotic liver tissues.
Wang L, Huang J, Jiang M, Zheng X
Tumour Biol. 2010
PubMed ID: 20532728
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Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway.
Koike S, Keino-Masu K, Masu M
Biochem Biophys Res Commun. 2010
PubMed ID: 20692235
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Low alpha-fetoprotein hepatocellular carcinoma.
Carr BI, Pancoska P, Branch RA
J Gastroenterol Hepatol. 2010
PubMed ID: 20796153
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Clinicopathologic features and prognostic factors in alpha-fetoprotein-producing gastric cancers: analysis of 104 cases.
Liu X, Cheng Y, Sheng W, Lu H, Xu Y, Long Z, Zhu H, Wang Y
J Surg Oncol. 2010
PubMed ID: 20740583
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High-efficient expression, refolding and purification of functional recombinant C-terminal fragment of human alpha-fetoprotein.
Sharapova OA, Pozdnykova NV, Laurinavichyute DK, Yurkova MS, Posypanova GA, Fedorov AN, Severin SE, Severin ES
Protein Expr Purif. 2010
PubMed ID: 20363333
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Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.
Morsut L, Yan KP, Enzo E, Aragona M, Soligo SM, Wendling O, Mark M, Khetchoumian K, Bressan G, Chambon P, Dupont S, Losson R, Piccolo S
Development. 2010
PubMed ID: 20573697
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Alpha-fetoprotein producing cells act as cancer progenitor cells in human cholangiocarcinoma.
Ishii T, Yasuchika K, Suemori H, Nakatsuji N, Ikai I, Uemoto S
Cancer Lett. 2010
PubMed ID: 20149523
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In utero exposure to di-(2-ethylhexyl) phthalate affects liver morphology and metabolism in post-natal CD-1 mice.
Maranghi F, Lorenzetti S, Tassinari R, Moracci G, Tassinari V, Marcoccia D, Di Virgilio A, Eusepi A, Romeo A, Magrelli A, Salvatore M, Tosto F, Viganotti M, Antoccia A, Di Masi A, Azzalin G, Tanzarella C, Macino G, Taruscio D, Mantovani A
Reprod Toxicol. 2010
PubMed ID: 20307648
-
Ectoderm, endoderm, and the evolution of heterodont dentitions.
Ohazama A, Haworth KE, Ota MS, Khonsari RH, Sharpe PT
Genesis. 2010
PubMed ID: 20533405
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Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.
Chu J, Shen MM
Dev Biol. 2010
PubMed ID: 20346354
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Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells.
Taube JH, Allton K, Duncan SA, Shen L, Barton MC
J Biol Chem. 2010
PubMed ID: 20348100
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The alpha-fetoprotein knock-out mouse model suggests that parental behavior is sexually differentiated under the influence of prenatal estradiol.
Keller M, Pawluski JL, Brock O, Douhard Q, Bakker J
Horm Behav. 2010
PubMed ID: 20109458
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[The effect of allogenic hematopoietic stem cell transplantation on tumor recurrence and metastasis of hepatocellular carcinoma after hepatectomy and the relationship with presence of AFP mRNA and VEGF-C mRNA in peripheral blood].
Deng ZG, Li B, Zu C
Sichuan Da Xue Xue Bao Yi Xue Ban. 2010
PubMed ID: 20506647
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Alpha-fetoprotein gene polymorphisms and risk of HCC and cirrhosis.
Suriapranata IM, Sudania WM, Tjong WY, Suciptan AA, Gani RA, Hasan I, Sanityoso A, Budihusodo U, Miskad UA, Akil F, Lelosutan SA, Martamala R, Yusuf I, Lesmana LA, Sulaiman A, Tai S
Clin Chim Acta. 2010
PubMed ID: 19968979
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Alpha-fetoprotein and tumour size are associated with microvascular invasion in explanted livers of patients undergoing transplantation with hepatocellular carcinoma.
McHugh PP, Gilbert J, Vera S, Koch A, Ranjan D, Gedaly R
HPB (Oxford). 2010
PubMed ID: 20495646
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Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression.
Song H, Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, Wang CY, Gao B, Jiang J, Yang Y
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20080598
-
Foxh1 and Foxa2 are not required for formation of the midgut and hindgut definitive endoderm.
McKnight KD, Hou J, Hoodless PA
Dev Biol. 2010
PubMed ID: 19896480
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Differential diagnosis of liver diseases using serum biomarkers.
Cujic D, Golubovic S, Bojic-Trbojevic Z, Ilic N, Baricevic I, Nedic O
J BUON. 2010
PubMed ID: 20414942
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The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development.
Beck L, Leroy C, Beck-Cormier S, Forand A, Salaün C, Paris N, Bernier A, Ureña-Torres P, Prié D, Ollero M, Coulombel L, Friedlander G
PLoS One. 2010
PubMed ID: 20161774
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Progression of alphafetoprotein before liver transplantation for hepatocellular carcinoma in cirrhotic patients: a critical factor.
Vibert E, Azoulay D, Hoti E, Iacopinelli S, Samuel D, Salloum C, Lemoine A, Bismuth H, Castaing D, Adam R
Am J Transplant. 2010
PubMed ID: 20070666
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The prognostic significance of preoperative plasma levels of osteopontin in patients with TNM stage-I of hepatocellular carcinoma.
Sun J, Xu HM, Zhou HJ, Dong QZ, Zhao Y, Fu LY, Hei ZY, Ye QH, Ren N, Jia HL, Qin LX
J Cancer Res Clin Oncol. 2010
PubMed ID: 19593583
-
The alpha-fetoprotein enhancer region activates the albumin and alpha-fetoprotein promoters during liver development.
Jin L, Long L, Green MA, Spear BT
Dev Biol. 2009
PubMed ID: 19782060
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Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.
Oh S, Lee D, Kim T, Kim TS, Oh HJ, Hwang CY, Kong YY, Kwon KS, Lim DS
Mol Cell Biol. 2009
PubMed ID: 19786569
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Cytoplasmic alpha-fetoprotein functions as a co-repressor in RA-RAR signaling to promote the growth of human hepatoma Bel 7402 cells.
Li M, Li H, Li C, Guo L, Liu H, Zhou S, Liu X, Chen Z, Shi S, Wei J, McNutt MA, Li G
Cancer Lett. 2009
PubMed ID: 19501957
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alpha-Fetoprotein as a modulator of the pro-inflammatory response of human keratinocytes.
Potapovich AI, Pastore S, Kostyuk VA, Lulli D, Mariani V, De Luca C, Dudich EI, Korkina LG
Br J Pharmacol. 2009
PubMed ID: 19785658
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Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.
Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N
Liver Int. 2009
PubMed ID: 19737349
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Serum alpha-fetoprotein levels during and after interferon therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis C.
Tamura Y, Yamagiwa S, Aoki Y, Kurita S, Suda T, Ohkoshi S, Nomoto M, Aoyagi Y, Niigata Liver Disease Study Group
Dig Dis Sci. 2009
PubMed ID: 19093203
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Diagnostic utility of SALL4 in extragonadal yolk sac tumors: an immunohistochemical study of 59 cases with comparison to placental-like alkaline phosphatase, alpha-fetoprotein, and glypican-3.
Wang F, Liu A, Peng Y, Rakheja D, Wei L, Xue D, Xue D, Allan RW, Molberg KH, Li J, Cao D
Am J Surg Pathol. 2009
PubMed ID: 19574883
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Alpha-fetoprotein related gene (ARG): A new member of the albumin gene family that is no longer functional in primates.
Naidu S, Peterson ML, Spear BT
Gene. 2009
PubMed ID: 19733224
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Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.
Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N
J Cell Biochem. 2009
PubMed ID: 19562671
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Novel alpha-fetoprotein-V messenger RNA isoforms in humans.
Tagaya H, Fukasawa H, Shoda T, Hoshi K, Hirata S
Reprod Sci. 2009
PubMed ID: 19494365
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Alpha-fetoprotein and human telomerase reverse transcriptase mRNA levels in peripheral blood of patients with hepatocellular carcinoma.
Kong SY, Park JW, Kim JO, Lee NO, Lee JA, Park KW, Hong EK, Kim CM
J Cancer Res Clin Oncol. 2009
PubMed ID: 19184104
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Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell. 2009
PubMed ID: 19615732
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Is elevated maternal serum alpha-fetoprotein in the second trimester of pregnancy associated with increased preterm birth risk? A systematic review and meta-analysis.
Yuan W, Chen L, Bernal AL
Eur J Obstet Gynecol Reprod Biol. 2009
PubMed ID: 19457604
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Alpha-fetoprotein, des-gamma carboxyprothrombin, and lectin-bound alpha-fetoprotein in early hepatocellular carcinoma.
Marrero JA, Feng Z, Wang Y, Nguyen MH, Befeler AS, Roberts LR, Reddy KR, Harnois D, Llovet JM, Normolle D, Dalhgren J, Chia D, Lok AS, Wagner PD, Srivastava S, Schwartz M
Gastroenterology. 2009
PubMed ID: 19362088
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AFP promoter enhancer increased specific expression of the human sodium iodide symporter (hNIS) for targeted radioiodine therapy of hepatocellular carcinoma.
Ma XJ, Huang R, Kuang AR
Cancer Invest. 2009
PubMed ID: 19241193
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Dynamic signaling network for the specification of embryonic pancreas and liver progenitors.
Wandzioch E, Zaret KS
Science. 2009
PubMed ID: 19556507
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Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas.
Pei Y, Kano J, Iijima T, Morishita Y, Inadome Y, Noguchi M
Virchows Arch. 2009
PubMed ID: 19437037
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[Recombinant plasmid pEGFP-AFP-TK delivered by nano-magnetic fluids targeting killed AFP positive HepG2 cells in vitro]
Luo Y, Zhang YD, Peng J, Yan HX, Xue D, Wu K, Zhou L, Hang SW, Zhao JF
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009
PubMed ID: 19426602
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Prognostic values of alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II in hepatitis B virus-related hepatocellular carcinoma: a prospective study.
Kim HS, Park JW, Jang JS, Kim HJ, Shin WG, Kim KH, Lee JH, Kim HY, Jang MK
J Clin Gastroenterol. 2009
PubMed ID: 19197197
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Expression and location of alpha-fetoprotein during rat colon development.
Liu XY, Dong D, Sun P, Du J, Gu L, Ge YB
World J Gastroenterol. 2009
PubMed ID: 19360917
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Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice.
Yamashita R, Takegawa Y, Sakumoto M, Nakahara M, Kawazu H, Hoshii T, Araki K, Yokouchi Y, Yamamura K
Dev Dyn. 2009
PubMed ID: 19301403
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The efficacy of serum carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) levels in determining the malignancy o
Bekci TT, Senol T, Maden E
J Int Med Res. 2009
PubMed ID: 19383238
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Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.
Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H
Gastroenterology. 2009
PubMed ID: 19185577
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Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development.
Li T, Huang J, Jiang Y, Zeng Y, He F, Zhang MQ, Han Z, Zhang X
Genomics. 2009
PubMed ID: 19015022
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Alpha-fetoprotein (AFP)-producing ovarian tumor in an elderly woman.
Isonishi S, Ogura A, Kiyokawa T, Suzuki M, Kunito S, Hirama M, Tachibana T, Ochiai K, Tanaka T
Int J Clin Oncol. 2009
PubMed ID: 19225928
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Essential and overlapping functions for mammalian Argonautes in microRNA silencing.
Su H, Trombly MI, Chen J, Wang X
Genes Dev. 2009
PubMed ID: 19174539
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The value of serum alpha-fetoprotein in predicting tumor recurrence after liver transplantation for hepatocellular carcinoma.
Xu X, Ke QH, Shao ZX, Wu J, Chen J, Zhou L, Zheng SS
Dig Dis Sci. 2009
PubMed ID: 18563566
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Mid-trimester maternal serum markers in predicting adverse pregnancy outcome.
Androutsopoulos G, Gkogkos P, Papadopoulos V, Adonakis G, Tsapanos V, Vassilakos P, Panayiotakis G, Decavalas G
Clin Exp Obstet Gynecol. 2009
PubMed ID: 20101856
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Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F
PLoS One. 2009
PubMed ID: 19865483
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Alpha-fetoprotein expressing metastastic adenocarcinoma of the esophago-gastric junction responding favorably to capecitabine and oxaliplatin.
Kripp M, Ströbel P, Dinter D, Lukan N, Hochhaus A, Hofheinz RD
Anticancer Drugs. 2009
PubMed ID: 19343004
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Undulant course of AFP: a sign of tumor activation or not?
Aydin GB, Hayran M, Büyükpamukçu M
Pediatr Hematol Oncol. 2009
PubMed ID: 19206006
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Clinical value of tumor markers in gestational trophoblastic diseases.
Ahmad AE, Dehaghani AS, Shaker M, Fattahi MJ
J Reprod Med. 2008
PubMed ID: 19160651
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Molecular background of alpha-fetoprotein in liver cancer cells as revealed by global RNA expression analysis.
Saito S, Ojima H, Ichikawa H, Hirohashi S, Kondo T
Cancer Sci. 2008
PubMed ID: 19038010
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Comprehensive analysis of the alpha-fetoprotein-specific CD8+ T cell responses in patients with hepatocellular carcinoma.
Thimme R, Neagu M, Boettler T, Neumann-Haefelin C, Kersting N, Geissler M, Makowiec F, Obermaier R, Hopt UT, Blum HE, Spangenberg HC
Hepatology. 2008
PubMed ID: 19003875
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The prognostic value of tumor markers in newly diagnosed patients with primary central nervous system germ cell tumors.
Kim A, Ji L, Balmaceda C, Diez B, Kellie SJ, Dunkel IJ, Gardner SL, Sposto R, Finlay JL
Pediatr Blood Cancer. 2008
PubMed ID: 18802946
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ZHX2 is a repressor of alpha-fetoprotein expression in human hepatoma cell lines.
Shen H, Luan F, Liu H, Gao L, Liang X, Zhang L, Sun W, Ma C
J Cell Mol Med. 2008
PubMed ID: 18194454
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Silencing alpha-fetoprotein expression induces growth arrest and apoptosis in human hepatocellular cancer cell.
Yang X, Zhang Y, Zhang L, Zhang L, Mao J
Cancer Lett. 2008
PubMed ID: 18657899
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The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages.
Kwon GS, Viotti M, Hadjantonakis AK
Dev Cell. 2008
PubMed ID: 18854136
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Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis.
Hou Y, Li F, Karin M, Ostrowski MC
Dev Dyn. 2008
PubMed ID: 18816823
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Des-gamma-carboxyprothrombin, alpha-fetoprotein and AFP-L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Durazo FA, Blatt LM, Corey WG, Lin JH, Han S, Saab S, Busuttil RW, Tong MJ
J Gastroenterol Hepatol. 2008
PubMed ID: 18422961
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Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cells.
Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC
J Hepatol. 2008
PubMed ID: 18617288
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Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.
Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I
Mol Cell. 2008
PubMed ID: 18722179
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Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver.
Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669658
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Crucial role of vHNF1 in vertebrate hepatic specification.
Lokmane L, Haumaitre C, Garcia-Villalba P, Anselme I, Schneider-Maunoury S, Cereghini S
Development. 2008
PubMed ID: 18635606
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Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma.
Akuta N, Suzuki F, Kawamura Y, Yatsuji H, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Arase Y, Ikeda K, Kumada H
J Med Virol. 2008
PubMed ID: 18551609
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Targeting alpha-fetoprotein represses the proliferation of hepatoma cells via regulation of the cell cycle.
Tang H, Tang XY, Liu M, Li X
Clin Chim Acta. 2008
PubMed ID: 18485897
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Alpha-fetoprotein and human chorionic gonadotrophin-beta as prognostic markers in neuroendocrine tumour patients.
Shah T, Srirajaskanthan R, Bhogal M, Toubanakis C, Meyer T, Noonan A, Witney-Smith C, Amin T, Bhogal P, Sivathasan N, Warner B, Hochhauser D, Caplin ME
Br J Cancer. 2008
PubMed ID: 18577995
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Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine.
Tomizawa M, Toyama Y, Ito C, Toshimori K, Iwase K, Takiguchi M, Saisho H, Yokosuka O
Cell Tissue Res. 2008
PubMed ID: 18478268
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Clinical significance of alpha-fetoprotein: involvement in proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma.
Mitsuhashi N, Kobayashi S, Doki T, Kimura F, Shimizu H, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Nozawa S, Furukawa K, Takeuchi D, Suda K, Miura S, Miyazaki M
J Gastroenterol Hepatol. 2008
PubMed ID: 18466288
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Glycomic analysis of alpha-fetoprotein L3 in hepatoma cell lines and hepatocellular carcinoma patients.
Nakagawa T, Miyoshi E, Yakushijin T, Hiramatsu N, Igura T, Hayashi N, Taniguchi N, Kondo A
J Proteome Res. 2008
PubMed ID: 18479159
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Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.
Maretto S, Müller PS, Aricescu AR, Cho KW, Bikoff EK, Robertson EJ
Dev Biol. 2008
PubMed ID: 18448090
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ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.
Lee D, Park C, Lee H, Lugus JJ, Kim SH, Arentson E, Chung YS, Gomez G, Kyba M, Lin S, Janknecht R, Lim DS, Choi K
Cell Stem Cell. 2008
PubMed ID: 18462699
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Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.
Suzuki A, Sekiya S, Büscher D, Izpisúa Belmonte JC, Taniguchi H
Development. 2008
PubMed ID: 18356246
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Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.
Sawada A, Kiyonari H, Ukita K, Nishioka N, Imuta Y, Sasaki H
Mol Cell Biol. 2008
PubMed ID: 18332127
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Absence of gonadotropin-releasing hormone 1 and Kiss1 activation in alpha-fetoprotein knockout mice: prenatal estrogens defeminize the potential to show preovulatory luteinizing hormone surges.
González-Martínez D, De Mees C, Douhard Q, Szpirer C, Bakker J
Endocrinology. 2008
PubMed ID: 18202134
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Clinicopathologic characteristics of intrahepatic cholangiocarcinoma in patients with positive serum a-fetoprotein.
Zhou YM, Yang JM, Li B, Yin ZF, Xu F, Wang B, Liu P, Li ZM
World J Gastroenterol. 2008
PubMed ID: 18407604
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Human CD4(+) T cells recognize an epitope within alpha-fetoprotein sequence and develop into TGF-beta-producing CD4(+) T cells.
Alisa A, Boswell S, Pathan AA, Ayaru L, Williams R, Behboudi S
J Immunol. 2008
PubMed ID: 18354237
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EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma.
Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H, Budhu A, Zanetti KA, Chen Y, Qin LX, Tang ZY, Wang XW
Cancer Res. 2008
PubMed ID: 18316609
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Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.
Arnold SJ, Hofmann UK, Bikoff EK, Robertson EJ
Development. 2008
PubMed ID: 18171685
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Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study.
Bjerner J, Høgetveit A, Wold Akselberg K, Vangsnes K, Paus E, Bjøro T, Børmer OP, Nustad K
Scand J Clin Lab Invest. 2008
PubMed ID: 18609108
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[Correlation of perioperative alpha-fetoprotein expression in peripheral blood to recurrence of hepatocellular carcinoma]
Shi M, Zhang Y, Zhong C, Lin XJ, Zhang CQ, Li JQ
Ai Zheng. 2008
PubMed ID: 18184471
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Prognostic analysis of Japanese men with metastatic germ cell tumors showing favorable response to bleomycin, etoposide and cisplatin as first-line chemotherapy.
Kumano M, Miyake H, Hara I, Muramaki M, Takenaka A, Fujisawa M
Hinyokika Kiyo. 2007
PubMed ID: 18203521
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Kinetics of albumin- and alpha-fetoprotein-production during rat liver development.
Elmaouhoub A, Dudas J, Ramadori G
Histochem Cell Biol. 2007
PubMed ID: 17879097
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Pharmacokinetics of diclofenac in rats intoxicated with CCL4, and in the regenerating liver.
Reyes-Gordillo K, Muriel P, Castañeda-Hernández G, Favari L
Biopharm Drug Dispos. 2007
PubMed ID: 17828713
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Assessment of 54 biomarkers for biopsy-detectable prostate cancer.
Parekh DJ, Ankerst DP, Baillargeon J, Higgins B, Platz EA, Troyer D, Hernandez J, Leach RJ, Lokshin A, Thompson IM
Cancer Epidemiol Biomarkers Prev. 2007
PubMed ID: 17932343
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Alpha-fetoprotein is dynamically expressed in rat pancreas during development.
Liu L, Guo J, Yuan L, Cheng M, Cao L, Shi H, Tong H, Wang N, De W
Dev Growth Differ. 2007
PubMed ID: 17880577
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Development of multimarker panel for early detection of endometrial cancer. High diagnostic power of prolactin.
Yurkovetsky Z, Ta'asan S, Skates S, Rand A, Lomakin A, Linkov F, Marrangoni A, Velikokhatnaya L, Winans M, Gorelik E, Maxwell GL, Lu K, Lokshin A
Gynecol Oncol. 2007
PubMed ID: 17659325
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GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion.
Wanderling S, Simen BB, Ostrovsky O, Ahmed NT, Vogen SM, Gidalevitz T, Argon Y
Mol Biol Cell. 2007
PubMed ID: 17634284
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Single nucleotide polymorphism in the promoter region of human alpha-fetoprotein (AFP) gene and its significance in hepatocellular carcinoma (HCC).
Chen GG, Ho RL, Wong J, Lee KF, Lai PB
Eur J Surg Oncol. 2007
PubMed ID: 17433605
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[Correlation of somatostatin receptor expression in human hepatocellular carcinoma tissue to serum alpha-fetoprotein concentration]
Xie YM, Yan LN, Wei B, Guo MM, Tang CW
Ai Zheng. 2007
PubMed ID: 17626741
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Mesenchymal hamartoma of the liver associated with features of Beckwith-Wiedemann syndrome and high serum alpha-fetoprotein levels.
Cajaiba MM, Sarita-Reyes C, Zambrano E, Reyes-Múgica M
Pediatr Dev Pathol. 2007
PubMed ID: 17535089
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Surgery in infants and children with testicular and paratesticular tumours: a single centre experience over a 25-year-period.
Tröbs RB, Krauss M, Geyer C, Tannapfel A, Körholz D, Hirsch W
Klin Padiatr. 2007
PubMed ID: 17525908
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Exposure to oestrogen prenatally does not interfere with the normal female-typical development of odour preferences.
Bakker J, De Mees C, Szpirer J, Szpirer C, Balthazart J
J Neuroendocrinol. 2007
PubMed ID: 17425607
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Significance of hepatitis B virus surface antigen, hepatitis C virus expression in hepatocellular carcinoma and pericarcinomatous tissues.
Xuan SY, Xin YN, Chen H, Shi GJ, Guan HS, Li Y
World J Gastroenterol. 2007
PubMed ID: 17465484
-
Identification of CCAAT enhancer binding protein alpha binding sites on the human alpha-fetoprotein gene.
Li HM, Ikeda H, Nakabayashi H, Nishi S, Sakai M
Gene. 2007
PubMed ID: 17188819
-
Unmasking of alpha-fetoprotein-specific CD4(+) T cell responses in hepatocellular carcinoma patients undergoing embolization.
Ayaru L, Pereira SP, Alisa A, Pathan AA, Williams R, Davidson B, Burroughs AK, Meyer T, Behboudi S
J Immunol. 2007
PubMed ID: 17237442
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Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure.
Shen J, Liu J, Xie Y, Diwan BA, Waalkes MP
Toxicol Sci. 2007
PubMed ID: 17077188
-
Effect of freeze-thaw cycles on serum measurements of AFP, CEA, CA125 and CA19-9.
Gao YC, Yuan ZB, Yang YD, Lu HK
Scand J Clin Lab Invest. 2007
PubMed ID: 17852813
-
Analysis of alpha-fetoprotein mRNA level on the tumor cell hematogenous spread of patients with hepatocellular carcinoma undergoing orthotopic liver transplantation.
Wang YL, Li G, Wu D, Liu YW, Yao Z
Transplant Proc. 2007
PubMed ID: 17275497
-
Alpha-fetoprotein-producing serous carcinoma of the uterus metastasizing to the ovaries, mimicking primary ovarian yolk sac tumor: a case report and review of the literature.
Tran TA, Ortiz HB, Holloway RW, Bigsby GE, Finkler NJ
Int J Gynecol Pathol. 2007
PubMed ID: 17197899
-
Alpha-fetoprotein mRNA detection in peripheral blood for prediction of hepatocellular carcinoma recurrence after liver transplantation.
Marubashi S, Dono K, Sugita Y, Asaoka T, Hama N, Gotoh K, Miyamoto A, Takeda Y, Nagano H, Umeshita K, Monden M
Transplant Proc. 2006
PubMed ID: 17175354
-
Comparison between human-telomerase reverse transcriptase mRNA and alpha-fetoprotein mRNA as a predictive value for recurrence of hepatocellular carcinoma in living donor liver transplantation.
Oya H, Sato Y, Yamamoto S, Nakatsuka H, Kobayashi T, Hara Y, Waguri N, Suda T, Aoyagi Y, Hatakeyama K
Transplant Proc. 2006
PubMed ID: 17175353
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Analysis of Nsdhl-deficient embryos reveals a role for Hedgehog signaling in early placental development.
Jiang F, Herman GE
Hum Mol Genet. 2006
PubMed ID: 17028112
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Characterization of distant enhancers and promoters in the albumin-alpha-fetoprotein locus during active and silenced expression.
Kajiyama Y, Tian J, Locker J
J Biol Chem. 2006
PubMed ID: 16893898
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The refolding of different alpha-fetoprotein variants.
Leong SS, Middelberg AP
Protein Sci. 2006
PubMed ID: 16882993
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Tg(Afp-GFP) expression marks primitive and definitive endoderm lineages during mouse development.
Kwon GS, Fraser ST, Eakin GS, Mangano M, Isern J, Sahr KE, Hadjantonakis AK, Baron MH
Dev Dyn. 2006
PubMed ID: 16708394
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Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
Dudich E, Semenkova L, Dudich I, Denesyuk A, Tatulov E, Korpela T
FEBS J. 2006
PubMed ID: 16869888
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The phenotypes of pluripotent human hepatic progenitors.
Schmelzer E, Wauthier E, Reid LM
Stem Cells. 2006
PubMed ID: 16627685
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AUF1-like protein binds specifically to DAS cis-acting element that regulates mouse alpha-fetoprotein gene expression.
Jiao R, He QY, Chen H, Hua Z, Jiao Q, Chiu JF
J Cell Biochem. 2006
PubMed ID: 16514630
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Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene.
Dame C, Kirschner KM, Bartz KV, Wallach T, Hussels CS, Scholz H
Blood. 2006
PubMed ID: 16467207
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Gene expression analysis identifies novel genes participating in early murine liver development and adult liver regeneration.
Jochheim-Richter A, Rüdrich U, Koczan D, Hillemann T, Tewes S, Petry M, Kispert A, Sharma AD, Attaran F, Manns MP, Ott M
Differentiation. 2006
PubMed ID: 16683987
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HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.
Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B
Genes Dev. 2006
PubMed ID: 16510872
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Alpha-fetoprotein controls female fertility and prenatal development of the gonadotropin-releasing hormone pathway through an antiestrogenic action.
De Mees C, Laes JF, Bakker J, Smitz J, Hennuy B, Van Vooren P, Gabant P, Szpirer J, Szpirer C
Mol Cell Biol. 2006
PubMed ID: 16479017
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Visceral endoderm function is regulated by quaking and required for vascular development.
Bohnsack BL, Lai L, Northrop JL, Justice MJ, Hirschi KK
Genesis. 2006
PubMed ID: 16470614
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Alpha-fetoprotein protects the developing female mouse brain from masculinization and defeminization by estrogens.
Bakker J, De Mees C, Douhard Q, Balthazart J, Gabant P, Szpirer J, Szpirer C
Nat Neurosci. 2006
PubMed ID: 16388309
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C/EBPalpha and C/EBPbeta are markers of early liver development.
Westmacott A, Burke ZD, Oliver G, Slack JM, Tosh D
Int J Dev Biol. 2006
PubMed ID: 16892179
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Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro.
Baharvand H, Hashemi SM, Kazemi Ashtiani S, Farrokhi A
Int J Dev Biol. 2006
PubMed ID: 16892178
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Expression of AFP and Rev-Erb A/Rev-Erb B and N-CoR in fetal rat liver, liver injury and liver regeneration.
Meier V, Tron K, Batusic D, Elmaouhoub A, Ramadori G
Comp Hepatol. 2006
PubMed ID: 16822301
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Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.
Machka C, Kersten M, Zobawa M, Harder A, Horsch M, Halder T, Lottspeich F, Hrabé de Angelis M, Beckers J
Gene Expr Patterns. 2005
PubMed ID: 15979417
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Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription.
Cui R, Nguyen TT, Taube JH, Stratton SA, Feuerman MH, Barton MC
J Biol Chem. 2005
PubMed ID: 16203738
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CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma.
Tan EH, Hooi SC, Laban M, Wong E, Ponniah S, Wee A, Wang ND
Cancer Res. 2005
PubMed ID: 16288022
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SCCA antigen combined with alpha-fetoprotein as serologic markers of HCC.
Giannelli G, Marinosci F, Trerotoli P, Volpe A, Quaranta M, Dentico P, Antonaci S
Int J Cancer. 2005
PubMed ID: 15906357
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Detecting AFP mRNA in peripheral blood of the patients with hepatocellular carcinoma, liver cirrhosis and hepatitis.
Yao F, Guo JM, Xu CF, Lou YL, Xiao BX, Zhou WH, Chen J, Hu YR, Liu Z, Hong GF
Clin Chim Acta. 2005
PubMed ID: 15993394
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A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
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Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
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The initiation of liver development is dependent on Foxa transcription factors.
Lee CS, Friedman JR, Fulmer JT, Kaestner KH
Nature. 2005
PubMed ID: 15959514
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Alpha-fetoprotein triggers hepatoma cells escaping from immune surveillance through altering the expression of Fas/FasL and tumor necrosis factor related apoptosis-inducing ligand and its receptor of lymphocytes and liver cancer cells.
Li MS, Ma QL, Chen Q, Liu XH, Li PF, Du GG, Li G
World J Gastroenterol. 2005
PubMed ID: 15849812
-
GATA6 is essential for embryonic development of the liver but dispensable for early heart formation.
Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey EE, Duncan SA
Mol Cell Biol. 2005
PubMed ID: 15767668
-
Hereditary persistence of alpha-fetoprotein and H19 expression in liver of BALB/cJ mice is due to a retrovirus insertion in the Zhx2 gene.
Perincheri S, Dingle RW, Peterson ML, Spear BT
Proc Natl Acad Sci U S A. 2005
PubMed ID: 15626755
-
Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.
Woda JM, Calzonetti T, Hilditch-Maguire P, Duyao MP, Conlon RA, MacDonald ME
BMC Dev Biol. 2005
PubMed ID: 16109169
-
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
-
The role of notch signaling in the development of intrahepatic bile ducts.
Kodama Y, Hijikata M, Kageyama R, Shimotohno K, Chiba T
Gastroenterology. 2004
PubMed ID: 15578515
-
Lhx2-/- mice develop liver fibrosis.
Wandzioch E, Kolterud A, Jacobsson M, Friedman SL, Carlsson L
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15536133
-
Suppression of C/EBP alpha expression in biliary cell differentiation from hepatoblasts during mouse liver development.
Shiojiri N, Takeshita K, Yamasaki H, Iwata T
J Hepatol. 2004
PubMed ID: 15519652
-
FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo.
Long L, Spear BT
Mol Cell Biol. 2004
PubMed ID: 15485926
-
High alpha-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: significance of hepatitis virus infection, age, p53 and beta-catenin mutations.
Peng SY, Chen WJ, Lai PL, Jeng YM, Sheu JC, Hsu HC
Int J Cancer. 2004
PubMed ID: 15305374
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
-
Congenital deficiency of alpha feto-protein.
Sharony R, Zadik I, Parvari R
Eur J Hum Genet. 2004
PubMed ID: 15280901
-
Amelogenesis imperfecta in a new animal model--a mutation in chromosome 5 (human 4q21).
Seedorf H, Springer IN, Grundner-Culemann E, Albers HK, Reis A, Fuchs H, Hrabe de Angelis M, Açil Y
J Dent Res. 2004
PubMed ID: 15271968
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Alpha-fetoprotein impairs APC function and induces their apoptosis.
Um SH, Mulhall C, Alisa A, Ives AR, Karani J, Williams R, Bertoletti A, Behboudi S
J Immunol. 2004
PubMed ID: 15265907
-
Smad2 and Smad3 coordinately regulate craniofacial and endodermal development.
Liu Y, Festing M, Thompson JC, Hester M, Rankin S, El-Hodiri HM, Zorn AM, Weinstein M
Dev Biol. 2004
PubMed ID: 15183723
-
Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation.
Bohnsack BL, Lai L, Dolle P, Hirschi KK
Genes Dev. 2004
PubMed ID: 15175265
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High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome Res. 2004
PubMed ID: 15060019
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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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Nature. 2004
PubMed ID: 15057822
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Beta-catenin is temporally regulated during normal liver development.
Micsenyi A, Tan X, Sneddon T, Luo JH, Michalopoulos GK, Monga SP
Gastroenterology. 2004
PubMed ID: 15057752
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Striking differences between the mouse and the human alpha-fetoprotein enhancers.
Long L, Davidson JN, Spear BT
Genomics. 2004
PubMed ID: 15028291
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Alpha-fetoprotein stimulated the expression of some oncogenes in human hepatocellular carcinoma Bel 7402 cells.
Li MS, Li PF, Chen Q, Du GG, Li G
World J Gastroenterol. 2004
PubMed ID: 15040024
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Oncodevelopmental alpha-fetoprotein acts as a selective proangiogenic factor on endothelial cell from the fetomaternal unit.
Liang OD, Korff T, Eckhardt J, Rifaat J, Baal N, Herr F, Preissner KT, Zygmunt M
J Clin Endocrinol Metab. 2004
PubMed ID: 15001643
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Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1.
Hartner JC, Schmittwolf C, Kispert A, Müller AM, Higuchi M, Seeburg PH
J Biol Chem. 2004
PubMed ID: 14615479
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Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes.
Jochheim A, Hillemann T, Kania G, Scharf J, Attaran M, Manns MP, Wobus AM, Ott M
Int J Dev Biol. 2004
PubMed ID: 15005571
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
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Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart.
Martin CM, Meeson AP, Robertson SM, Hawke TJ, Richardson JA, Bates S, Goetsch SC, Gallardo TD, Garry DJ
Dev Biol. 2004
PubMed ID: 14697368
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Immunohistochemical expression of pi class glutathione S-transferase and alpha-fetoprotein in hepatocellular carcinoma and chronic liver disease.
Yusof YA, Yan KL, Hussain SN
Anal Quant Cytol Histol. 2003
PubMed ID: 14714299
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Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.
Morkel M, Huelsken J, Wakamiya M, Ding J, van de Wetering M, Clevers H, Taketo MM, Behringer RR, Shen MM, Birchmeier W
Development. 2003
PubMed ID: 14623818
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Alpha-fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation.
Semenkova L, Dudich E, Dudich I, Tokhtamisheva N, Tatulov E, Okruzhnov Y, Garcia-Foncillas J, Palop-Cubillo JA, Korpela T
Eur J Biochem. 2003
PubMed ID: 14622304
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The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver.
Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG
J Immunol. 2003
PubMed ID: 12874218
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Impaired differentiation of fetal hepatocytes in homozygous jumonji mice.
Anzai H, Kamiya A, Shirato H, Takeuchi T, Miyajima A
Mech Dev. 2003
PubMed ID: 12915229
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Are amniotic fluid alpha-fetoprotein levels influenced by the gender in twin pairs?
Sharony R, Drugan A, Amiel A, Grinshpun-Cohen J, Markov S, Fejgin MD
Fetal Diagn Ther. 2003
PubMed ID: 12835590
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Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y
Genome Res. 2003
PubMed ID: 12819125
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Angiomotin regulates visceral endoderm movements during mouse embryogenesis.
Shimono A, Behringer RR
Curr Biol. 2003
PubMed ID: 12676095
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Maternal serum hCG and alpha-fetoprotein levels in pregnancies conceived after IVF or ICSI with fresh and frozen-thawed embryos.
Hui PW, Tang MH, Lam YH, Ng EH, Yeung WS, Ho PC
Hum Reprod. 2003
PubMed ID: 12615827
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Hepatocyte nuclear factor-6 stimulates transcription of the alpha-fetoprotein gene and synergizes with the retinoic-acid-receptor-related orphan receptor alpha-4.
Nacer-Cherif H, Bois-Joyeux B, Rousseau GG, Lemaigre FP, Danan JL
Biochem J. 2003
PubMed ID: 12379144
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Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice.
Tang Y, Katuri V, Dillner A, Mishra B, Deng CX, Mishra L
Science. 2003
PubMed ID: 12543979
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Multi-stage analysis of differential gene expression in BALB/C mouse liver development by high-density microarrays.
Jochheim A, Cieslak A, Hillemann T, Cantz T, Scharf J, Manns MP, Ott M
Differentiation. 2003
PubMed ID: 12558604
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
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Biological role of alpha-fetoprotein in cancer: prospects for anticancer therapy.
Mizejewski GJ
Expert Rev Anticancer Ther. 2002
PubMed ID: 12503217
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Differential protein expression at the stage of neural tube closure in the mouse embryo.
Greene ND, Leung KY, Wait R, Begum S, Dunn MJ, Copp AJ
J Biol Chem. 2002
PubMed ID: 12200422
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SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis.
Watanabe T, Nakagawa K, Ohata S, Kitagawa D, Nishitai G, Seo J, Tanemura S, Shimizu N, Kishimoto H, Wada T, Aoki J, Arai H, Iwatsubo T, Mochita M, Watanabe T, Satake M, Ito Y, Matsuyama T, Mak TW, Penninger JM, Nishina H, Katada T
Dev Biol. 2002
PubMed ID: 12376107
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Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility.
Gabant P, Forrester L, Nichols J, Van Reeth T, De Mees C, Pajack B, Watt A, Smitz J, Alexandre H, Szpirer C, Szpirer J
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12297623
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Alpha-fetoprotein gene expression in early and full-term human trophoblast.
Lafuste P, Robert B, Mondon F, Danan JL, Rossi B, Duc-Goiran P, Mignot TM, Nunez EA, Benassayag C, Ferré F
Placenta. 2002
PubMed ID: 12361680
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Regulation of alpha-fetoprotein expression by Nkx2.8.
Kajiyama Y, Tian J, Locker J
Mol Cell Biol. 2002
PubMed ID: 12167706
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Human alpha-fetoprotein binds to primary macrophages.
Atemezem A, Mbemba E, Marfaing R, Vaysse J, Pontet M, Saffar L, Charnaux N, Gattegno L
Biochem Biophys Res Commun. 2002
PubMed ID: 12176010
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Variant forms of alpha-fetoprotein transcripts expressed in human hematopoietic progenitors. Implications for their developmental potential towards endoderm.
Kubota H, Storms RW, Reid LM
J Biol Chem. 2002
PubMed ID: 12006569
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The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (FOXA).
Huang MC, Li KK, Spear BT
DNA Cell Biol. 2002
PubMed ID: 12215259
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Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo.
Hart AH, Hartley L, Sourris K, Stadler ES, Li R, Stanley EG, Tam PP, Elefanty AG, Robb L
Development. 2002
PubMed ID: 12117810
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The enzymatic basis for the conversion of nonfucosylated to fucosylated alpha-fetoprotein by acyclic retinoid treatment in human hepatoma cells: activation of alpha1-6 fucosyltransferase.
Noda K, Miyoshi E, Kitada T, Nakahara S, Gao CX, Honke K, Shiratori Y, Moriwaki H, Sasaki Y, Kasahara A, Hori M, Hayashi N, Taniguchi N
Tumour Biol. 2002
PubMed ID: 12499776
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Prenylcysteine carboxylmethyltransferase is essential for the earliest stages of liver development in mice.
Lin X, Jung J, Kang D, Xu B, Zaret KS, Zoghbi H
Gastroenterology. 2002
PubMed ID: 12105862
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On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Yang Y, Zhang M, Eggertsen G, Chiang JY
Biochim Biophys Acta. 2002
PubMed ID: 12069850
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The intracellular mechanism of alpha-fetoprotein promoting the proliferation of NIH 3T3 cells.
Li MS, Li PF, Yang FY, He SP, Du GG, Li G
Cell Res. 2002
PubMed ID: 12118941
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[Quantitation of alpha-fetoprotein messenger RNA in peripheral blood of nude mice and its relationship with tumor recurrence and metastasis after curative resection of hepatocellular carcinoma]
Wu X, Lin Z, Fan J, Lu J, Wang L, Tang Z
Zhonghua Gan Zang Bing Za Zhi. 2002
PubMed ID: 12113675
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Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population.
Rathjen J, Haines BP, Hudson KM, Nesci A, Dunn S, Rathjen PD
Development. 2002
PubMed ID: 12015293
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Depletion of definitive gut endoderm in Sox17-null mutant mice.
Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y
Development. 2002
PubMed ID: 11973269
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Calcitropic gene expression suggests a role for the intraplacental yolk sac in maternal-fetal calcium exchange.
Kovacs CS, Chafe LL, Woodland ML, McDonald KR, Fudge NJ, Wookey PJ
Am J Physiol Endocrinol Metab. 2002
PubMed ID: 11832378
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Repression of alpha-fetoprotein gene expression under hypoxic conditions in human hepatoma cells: characterization of a negative hypoxia response element that mediates opposite effects of hypoxia inducible factor-1 and c-Myc.
Mazure NM, Chauvet C, Bois-Joyeux B, Bernard MA, Nacer-Chérif H, Danan JL
Cancer Res. 2002
PubMed ID: 11861398
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Clinical significance of lens culinaris agglutinin-reactive fraction of serum alpha-fetoprotein in patients with hepatocellular carcinoma.
Yoshida S, Kurokohchi K, Arima K, Masaki T, Hosomi N, Funaki T, Murota M, Kita Y, Watanabe S, Kuriyama S
Int J Oncol. 2002
PubMed ID: 11788893
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Treatment of alpha-fetoprotein secreting hepatoblastoma by response of serum alpha-fetoprotein levels: a new concept.
Sayar D, Yaniv I, Goshen Y, Cohen IJ
Pediatr Hematol Oncol. 2001
PubMed ID: 11764100
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Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing.
Torres-Padilla ME, Fougère-Deschatrette C, Weiss MC
Mech Dev. 2001
PubMed ID: 11731232
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Glucocorticoid stimulates primate but inhibits rodent alpha-fetoprotein gene promoter.
Nakabayashi H, Koyama Y, Sakai M, Li HM, Wong NC, Nishi S
Biochem Biophys Res Commun. 2001
PubMed ID: 11549270
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Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation.
Tremblay KD, Dunn NR, Robertson EJ
Development. 2001
PubMed ID: 11566864
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Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development.
Weinstein M, Monga SP, Liu Y, Brodie SG, Tang Y, Li C, Mishra L, Deng CX
Mol Cell Biol. 2001
PubMed ID: 11438667
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Differences between human and mouse alpha-fetoprotein expression during early development.
Jones EA, Clement-Jones M, James OF, Wilson DI
J Anat. 2001
PubMed ID: 11430694
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Induction of the mammalian node requires Arkadia function in the extraembryonic lineages.
Episkopou V, Arkell R, Timmons PM, Walsh JJ, Andrew RL, Swan D
Nature. 2001
PubMed ID: 11298452
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The transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early development.
Andrews GK, Lee DK, Ravindra R, Lichtlen P, Sirito M, Sawadogo M, Schaffner W
EMBO J. 2001
PubMed ID: 11230134
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Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
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A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm.
Watt AJ, Jones EA, Ure JM, Peddie D, Wilson DI, Forrester LM
Mech Dev. 2001
PubMed ID: 11165478
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Immunohistochemical analysis of development of desmin-positive hepatic stellate cells in mouse liver.
Nitou M, Ishikawa K, Shiojiri N
J Anat. 2000
PubMed ID: 11197537
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RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
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Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage.
Keng VW, Yagi H, Ikawa M, Nagano T, Myint Z, Yamada K, Tanaka T, Sato A, Muramatsu I, Okabe M, Sato M, Noguchi T
Biochem Biophys Res Commun. 2000
PubMed ID: 11027604
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Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
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Identification of an enhancer and an alternative promoter in the first intron of the alpha-fetoprotein gene.
Scohy S, Gabant P, Szpirer C, Szpirer J
Nucleic Acids Res. 2000
PubMed ID: 11000266
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Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis.
Zwijsen A, van Rooijen MA, Goumans MJ, Dewulf N, Bosman EA, ten Dijke P, Mummery CL, Huylebroeck D
Dev Dyn. 2000
PubMed ID: 10906784
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Hepatocyte migration during liver development requires Prox1.
Sosa-Pineda B, Wigle JT, Oliver G
Nat Genet. 2000
PubMed ID: 10888866
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The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation.
Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS
Development. 2000
PubMed ID: 10804184
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BMP type II receptor is required for gastrulation and early development of mouse embryos.
Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, Miyazono K
Dev Biol. 2000
PubMed ID: 10772805
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Mice lacking Dad1, the defender against apoptotic death-1, express abnormal N-linked glycoproteins and undergo increased embryonic apoptosis.
Hong NA, Flannery M, Hsieh SN, Cado D, Pedersen R, Winoto A
Dev Biol. 2000
PubMed ID: 10720432
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An essential role in liver development for transcription factor XBP-1.
Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH
Genes Dev. 2000
PubMed ID: 10652269
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Blood biochemistry and endocrinology in the human fetus between 11 and 17 weeks of gestation.
Jauniaux E, Pahal G, Gervy C, Gulbis B
Reprod Biomed Online. 2000
PubMed ID: 12804197
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Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.
Constam DB, Robertson EJ
Development. 2000
PubMed ID: 10603343
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Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.
McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J
Dev Biol. 1999
PubMed ID: 10479460
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Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis.
Komada M, Soriano P
Genes Dev. 1999
PubMed ID: 10364163
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Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.
Kamiya A, Kinoshita T, Ito Y, Matsui T, Morikawa Y, Senba E, Nakashima K, Taga T, Yoshida K, Kishimoto T, Miyajima A
EMBO J. 1999
PubMed ID: 10205167
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Jumbled spine and ribs (Jsr): a new mutation on mouse chromosome 5.
Miyoshi H, Kon Y, Seo KW, Jin HK, Hasegawa A, Watanabe T
Mamm Genome. 1999
PubMed ID: 10051313
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p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding.
Lee KC, Crowe AJ, Barton MC
Mol Cell Biol. 1999
PubMed ID: 9891062
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Abrogation of the Cripto gene in mouse leads to failure of postgastrulation morphogenesis and lack of differentiation of cardiomyocytes.
Xu C, Liguori G, Persico MG, Adamson ED
Development. 1999
PubMed ID: 9876177
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High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
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Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation.
Guerra C, Koza RA, Walsh K, Kurtz DM, Wood PA, Kozak LP
J Clin Invest. 1998
PubMed ID: 9802886
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Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution.
Szpirer C, Szpirer J, Van Vooren P, Tissir F, Simon JS, Koike G, Jacob HJ, Lander ES, Helou K, Klinga-Levan K, Levan G
Mamm Genome. 1998
PubMed ID: 9716657
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Genomic organization, chromosomal mapping, and promoter analysis of the mouse dentin sialophosphoprotein (Dspp) gene, which codes for both dentin sialoprotein and dentin phosphoprotein.
Feng JQ, Luan X, Wallace J, Jing D, Ohshima T, Kulkarni AB, D'Souza RN, Kozak CA, MacDougall M
J Biol Chem. 1998
PubMed ID: 9545272
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Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues.
Dragatsis I, Efstratiadis A, Zeitlin S
Development. 1998
PubMed ID: 9502734
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Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo.
Waldrip WR, Bikoff EK, Hoodless PA, Wrana JL, Robertson EJ
Cell. 1998
PubMed ID: 9529255
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The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo.
Sirard C, de la Pompa JL, Elia A, Itie A, Mirtsos C, Cheung A, Hahn S, Wakeham A, Schwartz L, Kern SE, Rossant J, Mak TW
Genes Dev. 1998
PubMed ID: 9420335
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Localization of the bronx waltzer (bv) deafness gene to mouse chromosome 5.
Bussoli TJ, Kelly A, Steel KP
Mamm Genome. 1997
PubMed ID: 9321462
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X chromosome inactivation is mediated by Xist RNA stabilization.
Panning B, Dausman J, Jaenisch R
Cell. 1997
PubMed ID: 9298902
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The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.
King DP, Vitaterna MH, Chang AM, Dove WF, Pinto LH, Turek FW, Takahashi JS
Genetics. 1997
PubMed ID: 9215907
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Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.
Molkentin JD, Lin Q, Duncan SA, Olson EN
Genes Dev. 1997
PubMed ID: 9136933
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GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.
Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS, Soudais C, Leiden JM
Genes Dev. 1997
PubMed ID: 9136932
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Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac.
Farrington SM, Belaoussoff M, Baron MH
Mech Dev. 1997
PubMed ID: 9152011
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Serum amyloid A gene expression in rabbit, mink and mouse.
Marhaug G, Hackett B, Dowton SB
Clin Exp Immunol. 1997
PubMed ID: 9030885
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Negative regulation of the alpha-foetoprotein gene in fibroblasts: identification and characterization of cis and trans elements.
Henriette MF, Gabant P, Dreze PL, Szpirer C, Szpirer J
Folia Biol (Praha). 1997
PubMed ID: 9158943
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Oval cell proliferation associated with the murine insertional mutation TgN737Rpw.
Richards WG, Yoder BK, Isfort RJ, Detilleux PG, Foster C, Neilsen N, Woychik RP, Wilkinson JE
Am J Pathol. 1996
PubMed ID: 8952527
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Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.
Gualdi R, Bossard P, Zheng M, Hamada Y, Coleman JR, Zaret KS
Genes Dev. 1996
PubMed ID: 8682297
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The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family.
Galarneau L, Paré JF, Allard D, Hamel D, Levesque L, Tugwood JD, Green S, Bélanger L
Mol Cell Biol. 1996
PubMed ID: 8668203
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Sequence requirements for Afr-2 regulation of alpha-fetoprotein gene expression during liver regeneration.
Jin DK, Feuerman MH
Somat Cell Mol Genet. 1996
PubMed ID: 8914606
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Full-length sequence, localization, and chromosomal mapping of ameloblastin. A novel tooth-specific gene.
Krebsbach PH, Lee SK, Matsuki Y, Kozak CA, Yamada KM, Yamada Y
J Biol Chem. 1996
PubMed ID: 8626794
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Mapping of the human and mouse bone sialoprotein and osteopontin loci.
Crosby AH, Lyu MS, Lin K, McBride OW, Kerr JM, Aplin HM, Fisher LW, Young MF, Kozak CA, Dixon MJ
Mamm Genome. 1996
PubMed ID: 8835534
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Linkage between vitamin D-binding protein and alpha-fetoprotein in the mouse.
Guan XJ, Arhin G, Leung J, Tilghman SM
Mamm Genome. 1996
PubMed ID: 8835525
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Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut.
Hentsch B, Lyons I, Li R, Hartley L, Lints TJ, Adams JM, Harvey RP
Genes Dev. 1996
PubMed ID: 8557196
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Expression of serum albumin and of alphafetoprotein in murine normal and neoplastic primitive embryonic structures.
Trojan J, Naval X, Johnson T, Lafarge-Frayssinet C, Hajeri-Germond M, Farges O, Pan Y, Uriel J, Abramasky O, Ilan J
Mol Reprod Dev. 1995
PubMed ID: 8607965
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Differential gene expression during early murine yolk sac development.
Palis J, Kingsley PD
Mol Reprod Dev. 1995
PubMed ID: 8562047
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Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.
Robb L, Lyons I, Li R, Hartley L, Köntgen F, Harvey RP, Metcalf D, Begley CG
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7624372
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Developmental regulation of alpha-fetoprotein expression in intestinal epithelial cells of transgenic mice.
Cirillo LA, Emerson JA, Vacher J, Tyner AL
Dev Biol. 1995
PubMed ID: 7537233
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Specific endonucleolytic cleavages of mouse albumin mRNA and their modulation during liver development.
Tharun S, Sirdeshmukh R
Nucleic Acids Res. 1995
PubMed ID: 7899085
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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL.
Shivdasani RA, Mayer EL, Orkin SH
Nature. 1995
PubMed ID: 7830794
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Endogenous and transfected mouse alpha-fetoprotein genes in undifferentiated F9 cells are activated in transient heterokaryons.
Spear BT, Ellis AW
Somat Cell Mol Genet. 1995
PubMed ID: 7541561
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Intracisternal A-type particle elements as genetic markers: detection by repeat element viral element amplified locus-PCR.
Kaushik N, Stoye JP
Mamm Genome. 1994
PubMed ID: 7873878
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The inhibition of apoptosis by alpha-fetoprotein (AFP) and the role of AFP receptors in anti-cellular senescence.
Laderoute MP, Pilarski LM
Anticancer Res. 1994
PubMed ID: 7532927
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Expression of rat alpha-fetoprotein cDNA and its mutants in cultured mouse fibroblasts and identification of glycosylation sites related to electrophoretic variants.
Koyama Y, Nishi S
Biochim Biophys Acta. 1994
PubMed ID: 7524678
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Transient expression of bile-duct-specific cytokeratin in fetal mouse hepatocytes.
Shiojiri N
Cell Tissue Res. 1994
PubMed ID: 7525069
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Mouse alpha-fetoprotein gene 5' regulatory elements are required for postnatal regulation by raf and Rif.
Spear BT
Mol Cell Biol. 1994
PubMed ID: 7523852
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A new perspective on the nature of the cancer problem: anti-cellular senescence.
Laderoute MP
Mol Carcinog. 1994
PubMed ID: 7519015
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Analysis of the mechanism of glucocorticoid-mediated down regulation of the mouse alpha-fetoprotein gene.
Rabek JP, Zhang DE, Torres-Ramos CA, Papaconstantinou J
Biochim Biophys Acta. 1994
PubMed ID: 7517187
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New albumin gene 3' adjacent to the alpha 1-fetoprotein locus.
Bélanger L, Roy S, Allard D
J Biol Chem. 1994
PubMed ID: 7509788
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Murine bone sialoprotein (BSP): cDNA cloning, mRNA expression, and genetic mapping.
Young MF, Ibaraki K, Kerr JM, Lyu MS, Kozak CA
Mamm Genome. 1994
PubMed ID: 8180469
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The gamma phosphorylase kinase gene, Phkg, maps to mouse chromosome 5 near Gus.
Maichele AJ, Chamberlain JS
Mamm Genome. 1994
PubMed ID: 8111123
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Common antigen of oval and biliary epithelial cells (A6) is a differentiation marker of epithelial and erythroid cell lineages in early development of the mouse.
Engelhardt NV, Factor VM, Medvinsky AL, Baranov VN, Lazareva MN, Poltoranina VS
Differentiation. 1993
PubMed ID: 8299877
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Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome.
Halford S, Wilson DI, Daw SC, Roberts C, Wadey R, Kamath S, Wickremasinghe A, Burn J, Goodship J, Mattei MG
Hum Mol Genet. 1993
PubMed ID: 8268909
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Lessons from the repression of the alpha-fetoprotein gene in the adult liver.
Bilir BM
Hepatology. 1993
PubMed ID: 7691704
-
A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP).
McVey JH, Michaelides K, Hansen LP, Ferguson-Smith M, Tilghman S, Krumlauf R, Tuddenham EG
Hum Mol Genet. 1993
PubMed ID: 7684942
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A novel tyrosine kinase-related sequence on mouse chromosome 5.
Inglis JD, Lee M
Mamm Genome. 1993
PubMed ID: 8507985
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Map of seven polymorphic markers on rat chromosome 14: linkage conservation with human chromosome 4.
Remmers EF, Goldmuntz EA, Cash JM, Zha H, Crofford LJ, Misiewicz-Poltorak B, Mathern P, Wilder RL
Mamm Genome. 1993
PubMed ID: 8431642
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Close physical linkage of the FLT1 and FLT3 genes on chromosome 13 in man and chromosome 5 in mouse.
Rosnet O, Stephenson D, Mattei MG, Marchetto S, Shibuya M, Chapman VM, Birnbaum D
Oncogene. 1993
PubMed ID: 8380915
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Interaction of trans-acting factors with the proximal promoter of the mouse alpha-fetoprotein gene.
Ferrer N, Portugal J, Franco R
Int J Biochem. 1992
PubMed ID: 1282109
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Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles.
Cereghini S, Ott MO, Power S, Maury M
Development. 1992
PubMed ID: 1363228
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Proto-oncogene c-jun and c-fos messenger RNAs increase in the liver of carnitine-deficient juvenile visceral steatosis (jvs) mice.
Tomomura M, Nakagawa K, Saheki T
FEBS Lett. 1992
PubMed ID: 1383034
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Exogenous transferrin is taken up and localized by the neurulation-stage mouse embryo in vitro.
Copp AJ, Estibeiro JP, Brook FA, Downs KM
Dev Biol. 1992
PubMed ID: 1397688
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The zonal expression of alpha-fetoprotein transgenes in the livers of adult mice.
Emerson JA, Vacher J, Cirillo LA, Tilghman SM, Tyner AL
Dev Dyn. 1992
PubMed ID: 1284040
-
Rat gene mapping using PCR-analyzed microsatellites.
Serikawa T, Kuramoto T, Hilbert P, Mori M, Yamada J, Dubay CJ, Lindpainter K, Ganten D, Guénet JL, Lathrop GM
Genetics. 1992
PubMed ID: 1628813
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Characterization of a rat variant alpha-fetoprotein.
Watanabe T, Jimenez-Molina JL, Chou JY
Biochem Biophys Res Commun. 1992
PubMed ID: 1376990
-
A genetic map of the mouse suitable for typing intraspecific crosses.
Dietrich W, Katz H, Lincoln SE, Shin HS, Friedman J, Dracopoli NC, Lander ES
Genetics. 1992
PubMed ID: 1353738
-
Functional analysis of the mouse alpha-fetoprotein enhancers and their subfragments in primary mouse hepatocyte cultures.
Zhang DE, Rabek JP, Hsieh CC, Torres-Ramos C, Papaconstantinou J
J Biol Chem. 1992
PubMed ID: 1375227
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Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3).
Altherr MR, Wasmuth JJ, Seldin MF, Nadeau JH, Baehr W, Pittler SJ
Genomics. 1992
PubMed ID: 1315306
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Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.
Pittler SJ, Lee AK, Altherr MR, Howard TA, Seldin MF, Hurwitz RL, Wasmuth JJ, Baehr W
J Biol Chem. 1992
PubMed ID: 1372902
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Alpha-fetoprotein-mediated uptake of fatty acids by human T lymphocytes.
Torres JM, Anel A, Uriel J
J Cell Physiol. 1992
PubMed ID: 1371512
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Methylation of an alpha-foetoprotein gene intragenic site modulates gene activity.
Opdecamp K, Rivière M, Molné M, Szpirer J, Szpirer C
Nucleic Acids Res. 1992
PubMed ID: 1371343
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Mouse microsatellites from a flow-sorted 4:6 Robertsonian chromosome.
Cornall RJ, Friedman JM, Todd JA
Mamm Genome. 1992
PubMed ID: 1450512
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Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression.
Birkenmeier EH, Schneider U, Thurston SJ
Mamm Genome. 1992
PubMed ID: 1421760
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vHNF1 is expressed in epithelial cells of distinct embryonic origin during development and precedes HNF1 expression.
Ott MO, Rey-Campos J, Cereghini S, Yaniv M
Mech Dev. 1991
PubMed ID: 1685890
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The gene map of the Norway rat (Rattus norvegicus) and comparative mapping with mouse and man.
Levan G, Szpirer J, Szpirer C, Klinga K, Hanson C, Islam MQ
Genomics. 1991
PubMed ID: 1889815
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Serum biomarkers in metastatic renal cell carcinoma.
Dexeus FH, Logothetis CJ, Sella A, Fitz K, Striegel A, Amato RJ, Liu FJ
Urology. 1991
PubMed ID: 1714107
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Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5.
Smith EA, Seldin MF, Martinez L, Watson ML, Choudhury GG, Lalley PA, Pierce J, Aaronson S, Barker J, Naylor SL
Proc Natl Acad Sci U S A. 1991
PubMed ID: 1647018
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Human alpha-fetoprotein primary structure: a mass spectrometric study.
Pucci P, Siciliano R, Malorni A, Marino G, Tecce MF, Ceccarini C, Terrana B
Biochemistry. 1991
PubMed ID: 1709810
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Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis.
Schmid P, Cox D, Bilbe G, Maier R, McMaster GK
Development. 1991
PubMed ID: 2015789
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Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.
Stephenson DA, Mercola M, Anderson E, Wang CY, Stiles CD, Bowen-Pope DF, Chapman VM
Proc Natl Acad Sci U S A. 1991
PubMed ID: 1846043
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Expression of liver-specific functions and secretion of a hepatocyte growth factor by a newly established rat hepatoma cell line growing in a chemically-defined serum-free medium.
Miyazaki M, Bai L, Taga H, Hirai H, Sato J, Namba M
Res Exp Med (Berl). 1991
PubMed ID: 1836893
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Mononucleotide repeats are an abundant source of length variants in mouse genomic DNA.
Aitman TJ, Hearne CM, McAleer MA, Todd JA
Mamm Genome. 1991
PubMed ID: 1794049
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Inhibitory effect of acyclic retinoid (polyprenoic acid) on the secretion of alpha-fetoprotein in CCl4-treated rats.
Okuno M, Muto Y, Kato M, Ninomiya M, Moriwaki H, Noma A, Tagaya O, Nozaki Y, Suzuki Y
J Nutr Sci Vitaminol (Tokyo). 1990
PubMed ID: 1711115
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Fine mapping of a putative rd cDNA and its co-segregation with rd expression.
Danciger M, Bowes C, Kozak CA, LaVail MM, Farber DB
Invest Ophthalmol Vis Sci. 1990
PubMed ID: 1974892
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Interaction of human alpha fetoprotein with bilirubin.
Bansal V, Kumari K, Dixit A, Sahib MK
Indian J Exp Biol. 1990
PubMed ID: 1703124
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Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses.
Kozak CA, Albritton LM, Cunningham J
J Virol. 1990
PubMed ID: 2159567
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Assignment of 35 single-copy and 17 repetitive sequence DNA probes to human chromosome 3: high-resolution physical mapping of 7 DNA probes by in situ hybridization.
Atchison L, Cannizzaro L, Caamano J, Atchison M, Comis RL
Genomics. 1990
PubMed ID: 2328989
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The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.
Danciger M, Farber DB, Peyser M, Kozak CA
Genomics. 1990
PubMed ID: 2328987
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Localization of mouse melanoma growth stimulatory activity gene (Mgsa) between Afp and Gus on chromosome 5 using interspecific backcross mice.
Seldin MF, Martinez L, Howard TA, Naylor SL, Sakaguchi AY
Cytogenet Cell Genet. 1990
PubMed ID: 1979024
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The transcription control region of the rat alpha-fetoprotein gene. DNA sequence and homology studies.
Buzard G, Locker J
DNA Seq. 1990
PubMed ID: 1722723
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Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection.
Patarca R, Freeman GJ, Singh RP, Wei FY, Durfee T, Blattner F, Regnier DC, Kozak CA, Mock BA, Morse HC
J Exp Med. 1989
PubMed ID: 2787378
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Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo.
Downs KM, Martin GR, Bishop JM
Genes Dev. 1989
PubMed ID: 2663644
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Combinatorial control of positive and negative, upstream and intragenic regulatory DNA domains of the mouse alpha 1-foetoprotein gene.
Molné M, Houart C, Szpirer J, Szpirer C
Nucleic Acids Res. 1989
PubMed ID: 2471155
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Preferential expression of cellular retinoic acid binding protein in a subpopulation of neural cells in the developing mouse embryo.
Vaessen MJ, Kootwijk E, Mummery C, Hilkens J, Bootsma D, van Kessel AG
Differentiation. 1989
PubMed ID: 2547683
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Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.
Birkenmeier EH, Davisson MT, Beamer WG, Ganschow RE, Vogler CA, Gwynn B, Lyford KA, Maltais LM, Wawrzyniak CJ
J Clin Invest. 1989
PubMed ID: 2495302
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Chromosomal location of N-myc and L-myc genes in the mouse.
Campbell GR, Zimmerman K, Blank RD, Alt FW, D'Eustachio P
Oncogene Res. 1989
PubMed ID: 2654812
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Genetic analysis of the dominant white-spotting (W) region on mouse chromosome 5: identification of cloned DNA markers near W.
Geissler EN, Cheng SV, Gusella JF, Housman DE
Proc Natl Acad Sci U S A. 1988
PubMed ID: 3200849
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Mapping of the hooded, Gc protein, and albumin gene loci in linkage group VI of the laboratory rat.
Shumiya S, Nagase S
Biochem Genet. 1988
PubMed ID: 3242495
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Fetal and variant alpha-fetoproteins are encoded by mRNAs that differ in sequence at the 5' end.
Wan YJ, Jimenez-Molina JL, Chou JY
Biochemistry. 1988
PubMed ID: 2462901
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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus.
Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A
Nature. 1988
PubMed ID: 2457811
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A highly conserved mouse gene with a propensity to form pseudogenes in mammals.
Heller DL, Gianola KM, Leinwand LA
Mol Cell Biol. 1988
PubMed ID: 3405219
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Chromosomal location of the regulator of mouse alpha-fetoprotein, Afr-1.
Blankenhorn EP, Duncan R, Huppi K, Potter M
Genetics. 1988
PubMed ID: 2456965
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Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.
Wilkinson DG, Peters G, Dickson C, McMahon AP
EMBO J. 1988
PubMed ID: 3293998
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The rat gene map.
Szpirer C, Szpirer J, Islam MQ, Levan G
Curr Top Microbiol Immunol. 1988
PubMed ID: 3416641
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The rat alpha-fetoprotein and albumin genes. Transcriptional control and comparison of the sequence organization and promoter region.
Nahon JL, Danan JL, Poiret M, Tratner I, Jose-Estanyol M, Sala-Trepat JM
J Biol Chem. 1987
PubMed ID: 2442163
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Cell-lineage-specific expression of the mouse hsp68 gene during embryogenesis.
Kothary R, Perry MD, Moran LA, Rossant J
Dev Biol. 1987
PubMed ID: 3582732
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The regulation of albumin and alpha-fetoprotein gene expression in mammals.
Nahon JL
Biochimie. 1987
PubMed ID: 2445387
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Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene.
Gibbs PE, Zielinski R, Boyd C, Dugaiczyk A
Biochemistry. 1987
PubMed ID: 2436661
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The rat alpha 1-fetoprotein gene: characterization of the 5'-flanking region and tandem organization with the albumin gene.
Chevrette M, Guertin M, Turcotte B, Bélanger L
Nucleic Acids Res. 1987
PubMed ID: 2434929
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Tyrosine sulfation of proteins from the human hepatoma cell line HepG2.
Liu MC, Yu S, Sy J, Redman CM, Lipmann F
Proc Natl Acad Sci U S A. 1985
PubMed ID: 2414772
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The rate of molecular evolution of alpha-fetoprotein approaches that of pseudogenes.
Minghetti PP, Law SW, Dugaiczyk A
Mol Biol Evol. 1985
PubMed ID: 2452956
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The human alpha-fetoprotein gene. Sequence organization and the 5' flanking region.
Sakai M, Morinaga T, Urano Y, Watanabe K, Wegmann TG, Tamaoki T
J Biol Chem. 1985
PubMed ID: 2580830
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Rat alpha 1-fetoprotein messenger RNA: 5'-end sequence and glucocorticoid-suppressed liver transcription in an improved nuclear run-off assay.
Turcotte B, Guertin M, Chevrette M, Bélanger L
Nucleic Acids Res. 1985
PubMed ID: 2582363
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A lethal deletion on mouse chromosome 7 affects regulation of liver-cell-specific functions: posttranscriptional control of serum protein and transcriptional control of aldolase B synthesis.
Sala-Trepat JM, Poiret M, Sellem CH, Bessada R, Erdos T, Gluecksohn-Waelsch S
Proc Natl Acad Sci U S A. 1985
PubMed ID: 3857594
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Association of histone H1(0) with a gene repressed during liver development.
Roche J, Gorka C, Goeltz P, Lawrence JJ
Nature. 1985
PubMed ID: 2579343
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The structure and regulation of the alpha-fetoprotein and albumin genes.
Tilghman SM
Oxf Surv Eukaryot Genes. 1985
PubMed ID: 2474300
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Tandem arrangement of the albumin and alpha-fetoprotein genes in the human genome.
Urano Y, Sakai M, Watanabe K, Tamaoki T
Gene. 1984
PubMed ID: 6085063
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Expression of cellular oncogenes during embryonic and fetal development of the mouse.
Slamon DJ, Cline MJ
Proc Natl Acad Sci U S A. 1984
PubMed ID: 6594688
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Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes.
Pachnis V, Belayew A, Tilghman SM
Proc Natl Acad Sci U S A. 1984
PubMed ID: 6206499
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Localization of the L1Md family of repeated sequences in the mouse albumin-alpha-fetoprotein gene complex.
Cooper R, Herzog CE, Li ML, Zapisek WF, Hoyt PR, Ratrie H, Papaconstantinou J
Nucleic Acids Res. 1984
PubMed ID: 6206473
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Differential expression of albumin and alpha-fetoprotein genes in fetal tissues of mouse and rat.
Sellem CH, Frain M, Erdos T, Sala-Trepat JM
Dev Biol. 1984
PubMed ID: 6199242
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Expression of H-Y antigen by female mice carrying Sxr.
Simpson E, McLaren A, Chandler P, Tomonari K
Transplantation. 1984
PubMed ID: 6364482
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Human alpha-fetoprotein-fatty acid interaction.
Aussel C, Masseyeff R
Biochem Biophys Res Commun. 1983
PubMed ID: 6193792
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Primary structures of human alpha-fetoprotein and its mRNA.
Morinaga T, Sakai M, Wegmann TG, Tamaoki T
Proc Natl Acad Sci U S A. 1983
PubMed ID: 6192439
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Linkage of the evolutionarily-related serum albumin and alpha-fetoprotein genes within q11-22 of human chromosome 4.
Harper ME, Dugaiczyk A
Am J Hum Genet. 1983
PubMed ID: 6192711
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Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion.
Müller R, Verma IM, Adamson ED
EMBO J. 1983
PubMed ID: 6641714
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Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA.
Beattie WG, Dugaiczyk A
Gene. 1982
PubMed ID: 6187626
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Genetic analysis of alpha-fetoprotein synthesis in mice.
Belayew A, Tilghman SM
Mol Cell Biol. 1982
PubMed ID: 6186903
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J chain is encoded by a single gene unlinked to other immunoglobulin structural genes.
Yagi M, D'Eustachio P, Ruddle FH, Koshland ME
J Exp Med. 1982
PubMed ID: 6278047
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Intragenic amplification and divergence in the mouse alpha-fetoprotein gene.
Eiferman FA, Young PR, Scott RW, Tilghman SM
Nature. 1981
PubMed ID: 6172714
-
alpha-Fetoprotein and albumin genes are in tandem in the mouse genome.
Ingram RS, Scott RW, Tilghman SM
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6170978
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Sequence homology between RNAs encoding rat alpha-fetoprotein and rat serum albumin.
Jagodzinski LL, Sargent TD, Yang M, Glackin C, Bonner J
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6167988
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Homology between the primary structure of alpha-fetoprotein, deduced from a complete cDNA sequence, and serum albumin.
Law SW, Dugaiczyk A
Nature. 1981
PubMed ID: 6164927
-
Murine alpha-fetoprotein and albumin: two evolutionarily linked proteins encoded on the same mouse chromosome.
D'Eustachio P, Ingram RS, Tilghman SM, Ruddle FH
Somatic Cell Genet. 1981
PubMed ID: 6170120
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The evolution of alpha-fetoprotein and albumin. II. The structures of the alpha-fetoprotein and albumin genes in the mouse.
Kioussis D, Eiferman F, van de Rijn P, Gorin MB, Ingram RS, Tilghman SM
J Biol Chem. 1981
PubMed ID: 6161930
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The evolution of alpha-fetoprotein and albumin. I. A comparison of the primary amino acid sequences of mammalian alpha-fetoprotein and albumin.
Gorin MB, Cooper DL, Eiferman F, van de Rijn P, Tilghman SM
J Biol Chem. 1981
PubMed ID: 6161929
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alpha-Fetoprotein gene expression. Partial DNA sequence and COOH-terminal homology to albumin.
Innis MA, Miller DL
J Biol Chem. 1980
PubMed ID: 6157690
-
Amino acid sequence homology between rat alpha-fetoprotein and albumin at the COOH-terminal regions.
Liao WS, Hamilton RW, Taylor JM
J Biol Chem. 1980
PubMed ID: 6157681
-
Molecular cloning of DNA complementary to a mouse alpha-fetoprotein mRNA sequence.
Law S, Tamoaki T, Kreuzaler F, Dugaiczyk A
Gene. 1980
PubMed ID: 6157603
-
Structure of the alpha-fetoprotein gene in the mouse.
Gorin MB, Tilghman SM
Proc Natl Acad Sci U S A. 1980
PubMed ID: 6154931
-
alpha-Fetoprotein as a carrier protein in plasma and its bilirubin-binding ability.
Aoyagi Y, Ikenaka T, Ichida F
Cancer Res. 1979
PubMed ID: 89900
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The presence of intervening sequences in the alpha-fetoprotein gene of the mouse.
Tilghman SM, Kioussis D, Gorin MB, Ruiz JP, Ingram RS
J Biol Chem. 1979
PubMed ID: 88451
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Copper(II)-binding ability of human alpha-fetoprotein.
Aoyagi Y, Ikenaka T, Ichida F
Cancer Res. 1978
PubMed ID: 80265
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Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma.
Aoyagi Y, Ikenaka T, Ichida F
Cancer Res. 1977
PubMed ID: 71198
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Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis.
Yachnin S, Hsu R, Heinrikson RL, Miller JB
Biochim Biophys Acta. 1977
PubMed ID: 70228
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Synthesis of alpha-fetoprotein and some other serum proteins in testicular tumors.
Sakashita S, Nishi S, Hirai H, Tsuji I
Invest Urol. 1977
PubMed ID: 68943
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Genetic control of alpha-fetoprotein synthesis in the mouse.
Olsson M, Lindahl G, Ruoslahti E
J Exp Med. 1977
PubMed ID: 67170
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Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury.
Ruoslahti E, Pihko H, Vaheri A, Seppälä M, Virolainen M, Konttinen A
Johns Hopkins Med J Suppl. 1974
PubMed ID: 4138095
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