• About T1DBase
• Regions
  • Human T1D Regions
  • Mouse T1D Regions
    • Linkage Regions
    • Orthologous Regions
  • Rat T1D Regions
    • Linkage Regions
    • Orthologous Regions
    • QTL Regions
• Genome Browser
  • Human GBrowse
  • Mouse GBrowse
  • Rat GBrowse
• Tools
  • Gene Dossier
  • Beta Cell Gene Atlas
  • Batch Query
  • Sequence Search
  • HaemAtlas Search
  • Mouse Strain Search
• Data
  • Poster Pages
  • Downloads
  • Data Submission
• Help
  • FAQ
  • T1DBase Tutorial
• Contact Us

• Page Sections
  • Summary
  • Regions of Interest Overlapping this feature
  • Gene Overview
  • Beta Cell Gene Atlas
  • Tissue Expression
  • HaemAtlas Expression
  • Interactions
  • Cross-Reference to Pathways and GO Terms
  • Publications
  • Model Organism Phenotype Links
  • External Links
  • External resources (dkCOIN)

DHX9

Gene Description:   DEAH (Asp-Glu-Ala-His) box polypeptide 9 Synonyms:   HEL-5, FLJ17406, LKP, DDX9, AI326842, Dhx9, DHX9, mHEL-5, RHA, NDHII, MGC90954, Ddx9, NDH2 Orthologs:   Human DHX9 (protein-coding), Mouse Dhx9 (protein-coding), Rat Dhx9 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid, KEGG Human-Rat: HomoloGene, MGD, RGD, Inparanoid, KEGG Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Mouse: 2

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd5.4	Mouse	chr1:77143053..147306684	70.16	608
Idd5.4b	Mouse	chr1:152631809..157938163	5.31	58

(Human) GRCh37 - chr1:182808439..182857117 (48.68 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr1:155302888..155334790 (31.90 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr13:68471256..68507999 (36.74 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for DHX9: The DHX9 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs DHX9   RBM5   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   THOC4   Reactome  predicted  12176931  11991638  12477934  DHX9   HNRNPR   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   SRRM1   Reactome  predicted  12176931  11991638  12477934  DHX9   CD2BP2   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   NXF1   HPRD, MINT, IntAct, BioGRID  empirical  10924507  DHX9   PRPF8   HPRD  empirical  15034300  DHX9   KHDRBS1   HPRD, BioGRID  empirical  10951562  DHX9   MGEA5   HPRD  empirical  16169070  DHX9   HNRNPA0   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPUL1   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   DDX20   HPRD, BioGRID  empirical  11149922  DHX9   GABARAP   IntAct  empirical  20562859  DHX9   U2AF2   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   GABARAPL2   IntAct  empirical  20562859  DHX9   DHX9   HPRD  empirical  12711669  11402034  DHX9   EPB41   IntAct  empirical  17353931  DHX9   ESR1   IntAct  empirical  21182205  DHX9   EWSR1   BioGRID  empirical  16740692  DHX9   HNRNPA3   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   DNAJC8   Reactome  predicted  12176931  11991638  6088074  6206566  DHX9   GABARAPL1   IntAct  empirical  20562859  DHX9   FUS   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   XRCC6   BioGRID  empirical  15723802  DHX9   HINFP   BioGRID  empirical  12665568  DHX9   AKAP8L   HPRD, BioGRID  empirical  10748171  11402034  DHX9   SND1   BioGRID  empirical  16914450  DHX9   RBMX   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   GRB2   IntAct  empirical  12577067  DHX9   GTF2B   HPRD, BioGRID  empirical  11149922  DHX9   H2AFX   BioGRID  empirical  15613478  DHX9   HDLBP   HPRD, BioGRID  empirical  15723802  DHX9   HLA-B   IntAct  empirical  17353931  DHX9   HNRNPA1   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPA2B1   MINT, Reactome  empirical  18519039  12176931  12477934  6088074  6206566  DHX9   HNRNPC   HPRD, Reactome  empirical  15034300  12176931  12477934  6088074  6206566  DHX9   HNRNPD   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPF   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPH1   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPH2   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPK   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPL   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   HNRNPU   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   APBB1   BioGRID  empirical  16055720  DHX9   PRMT1   HPRD, IntAct, BioGRID  empirical  11850402  15084609  DHX9   ILF3   HPRD, BioGRID  empirical  12946349  15312759  DHX9   JUN   HPRD, BioGRID  empirical  11823437  DHX9   ARF6   IntAct  empirical  17353931  DHX9   ARHGDIA   IntAct, BioGRID  empirical  17353931  DHX9   MAP3K1   MINT, IntAct  empirical  14743216  DHX9   HNRNPM   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   NFKB2   MINT, IntAct  empirical  14743216  DHX9   NFX1   Reactome  predicted  12176931  11991638  12477934  DHX9   YBX1   IntAct, Reactome  empirical  20360068  12176931  11991638  12477934  6088074  6206566  DHX9   GEMIN4   HPRD, BioGRID  empirical  11149922  DHX9   PCBP1   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   PCBP2   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   PCNA   HPRD  empirical  12171929  DHX9   CDC40   Reactome  predicted  12176931  11991638  6088074  6206566  DHX9   ABCB1   BioGRID  empirical  14769796  DHX9   POLR2A   HPRD  empirical  11149922  DHX9   POU5F1   IntAct, BioGRID  empirical  20362542  DHX9   PINX1   IntAct  empirical  17353931  DHX9   LYAR   IntAct, BioGRID  empirical  17353931  DHX9   PRPF40A   BioGRID  empirical  16055720  DHX9   CCAR1   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   PRKDC   BioGRID  empirical  15613478  DHX9   MAPK13   IntAct  empirical  19135240  DHX9   MEPCE   BioGRID  empirical  17643375  DHX9   PTBP1   Reactome  predicted  12176931  12477934  6088074  6206566  DHX9   SUGP1   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   ACTA1   BioGRID  empirical  11687588  DHX9   RELA   HPRD, MINT, IntAct, BioGRID  empirical  15355351  14743216  DHX9   SRSF1   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   SRSF2   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   SRSF3   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   SRSF4   Reactome  predicted  12176931  11991638  6088074  6206566  DHX9   SRSF5   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   SRSF6   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   SRSF7   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   ZMAT3   MINT  empirical  18519039  DHX9   SMN1   HPRD  empirical  11149922  DHX9   SMN2   HPRD  empirical  11149922  DHX9   SNRPB   HPRD  empirical  11149922  DHX9   SNRPB2   HPRD  empirical  11149922  DHX9   BRCA1   HPRD, BioGRID  empirical  12592385  9662397  DHX9   SRPK1   HPRD  empirical  15034300  DHX9   SSRP1   HPRD  empirical  15034300  DHX9   STAU1   HPRD, IntAct  empirical  15121898  15303970  DHX9   TBP   HPRD, BioGRID  empirical  11149922  DHX9   TFE3   IntAct  empirical  17353931  DHX9   TOP1   IntAct  empirical  15848144  DHX9   TOP2A   HPRD, BioGRID  empirical  12711669  15034300  DHX9   TRAF6   IntAct  empirical  17353931  DHX9   U2AF1   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   UBC   BioGRID  empirical  16196087  DHX9   UBE2I   BioGRID  empirical  15312759  DHX9   WRN   BioGRID  empirical  17498979  DHX9   XRCC5   BioGRID  empirical  15723802  DHX9   YWHAZ   MINT  empirical  15161933  DHX9   CNBP   IntAct, BioGRID  empirical  17353931  DHX9   MAP1LC3B   IntAct  empirical  20562859  DHX9   SF3A2   MINT  empirical  17332742  DHX9   SMC1A   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   MAP1LC3A   IntAct  empirical  20562859  DHX9   GEMIN2   HPRD, BioGRID  empirical  11149922  DHX9   TP63   IntAct  empirical  20085233  DHX9   SRSF9   Reactome  predicted  12176931  11991638  12477934  6088074  6206566  DHX9   TNFRSF14   IntAct  empirical  17353931  DHX9   TNFRSF10D   IntAct  empirical  17353931  DHX9   MBD2   HPRD, BioGRID  empirical  12665568  DHX9   MAP3K14   MINT, IntAct  empirical  14743216  DHX9   PIAS2   BioGRID  empirical  15312759  DHX9   DDX21   IntAct  empirical  15034300  DHX9   SRSF11   Reactome  predicted  12176931  11991638  6088074  6206566  DHX9   DHX38   Reactome  predicted  12176931  11991638  6088074  6206566

View all

KEGG Network: None available   None available.

Biocarta: None available   None available.

Reactome: 7   Formation and Maturation of mRNA Transcript REACT_2039 Gene Expression REACT_71 mRNA Processing REACT_1675 mRNA Splicing REACT_1735 mRNA Splicing - Major Pathway REACT_467 Processing of Capped Intron-Containing Pre-mRNA REACT_125 Processing of Capped Transcripts REACT_1021

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 22   Nucleotide binding GO:0000166 Nuclear mRNA splicing, via spliceosome GO:0000398 DNA binding GO:0003677 RNA helicase activity GO:0003724 Double-stranded RNA binding GO:0003725 ATP-dependent DNA helicase activity GO:0004003 ATP-dependent RNA helicase activity GO:0004004 Protein binding GO:0005515 ATP binding GO:0005524 Intracellular GO:0005622 Nucleus GO:0005634 Nucleoplasm GO:0005654 Nucleolus GO:0005730 Cytoplasm GO:0005737 Centrosome GO:0005813 RNA splicing GO:0008380 Gene expression GO:0010467 Hydrolase activity GO:0016787 Ribonucleoprotein complex GO:0030529 Cellular response to heat GO:0034605 CRD-mediated mRNA stabilization GO:0070934 CRD-mediated mRNA stability complex GO:0070937

	KEGG Network: None available
	Biocarta: None available
	Reactome: 7 Formation and Maturation of mRNA Transcript REACT_2039 Gene Expression REACT_71 mRNA Processing REACT_1675 mRNA Splicing REACT_1735 mRNA Splicing - Major Pathway REACT_467 Processing of Capped Intron-Containing Pre-mRNA REACT_125 Processing of Capped Transcripts REACT_1021
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 22 Nucleotide binding GO:0000166 Nuclear mRNA splicing, via spliceosome GO:0000398 DNA binding GO:0003677 RNA helicase activity GO:0003724 Double-stranded RNA binding GO:0003725 ATP-dependent DNA helicase activity GO:0004003 ATP-dependent RNA helicase activity GO:0004004 Protein binding GO:0005515 ATP binding GO:0005524 Intracellular GO:0005622 Nucleus GO:0005634 Nucleoplasm GO:0005654 Nucleolus GO:0005730 Cytoplasm GO:0005737 Centrosome GO:0005813 RNA splicing GO:0008380 Gene expression GO:0010467 Hydrolase activity GO:0016787 Ribonucleoprotein complex GO:0030529 Cellular response to heat GO:0034605 CRD-mediated mRNA stabilization GO:0070934 CRD-mediated mRNA stability complex GO:0070937

Publications: 109

• Features of double-stranded RNA-binding domains of RNA helicase A are necessary for selective recognition and translation of complex mRNAs.
  Ranji A, Shkriabai N, Kvaratskhelia M, Musier-Forsyth K, Boris-Lawrie K
  J Biol Chem. 2011
  PubMed ID: 21123178
   
  
• Initial characterization of the human central proteome.
  Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
  BMC Syst Biol. 2011
  PubMed ID: 21269460
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus.
  Huo L, Wang YN, Xia W, Hsu SC, Lai CC, Li LY, Chang WC, Wang Y, Hsu MC, Yu YL, Huang TH, Ding Q, Chen CH, Tsai CH, Hung MC
  Proc Natl Acad Sci U S A. 2010
  PubMed ID: 20802156
   
  
• Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells.
  Kim T, Pazhoor S, Bao M, Zhang Z, Hanabuchi S, Facchinetti V, Bover L, Plumas J, Chaperot L, Qin J, Liu YJ
  Proc Natl Acad Sci U S A. 2010
  PubMed ID: 20696886
   
  
• Human DHX9 helicase unwinds triple-helical DNA structures.
  Jain A, Bacolla A, Chakraborty P, Grosse F, Vasquez KM
  Biochemistry. 2010
  PubMed ID: 20669935
   
  
• WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase.
  Chakraborty P, Grosse F
  Nucleic Acids Res. 2010
  PubMed ID: 20385589
   
  
• Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
  Schütz P, Wahlberg E, Karlberg T, Hammarström M, Collins R, Flores A, Schüler H
  J Mol Biol. 2010
  PubMed ID: 20510246
   
  
• An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.
  Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu MM, Choudhary J
  Cell Stem Cell. 2010
  PubMed ID: 20362542
   
  
• Kaposi's sarcoma-associated herpesvirus viral protein kinase interacts with RNA helicase a and regulates host gene expression.
  Jong JE, Park J, Kim S, Seo T
  J Microbiol. 2010
  PubMed ID: 20437153
   
  
• Lysine acetylation targets protein complexes and co-regulates major cellular functions.
  Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
  Science. 2009
  PubMed ID: 19608861
   
  
• RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II.
  Tang W, You W, Shi F, Qi T, Wang L, Djouder Z, Liu W, Zeng X
  Biochem J. 2009
  PubMed ID: 19309309
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• An antiviral response directed by PKR phosphorylation of the RNA helicase A.
  Sadler AJ, Latchoumanin O, Hawkes D, Mak J, Williams BR
  PLoS Pathog. 2009
  PubMed ID: 19229320
   
  
• Genetic sequence variations of BRCA1-interacting genes AURKA, BAP1, BARD1 and DHX9 in French Canadian Families with high risk of breast cancer.
  Guénard F, Labrie Y, Ouellette G, Joly Beauparlant C, Durocher F
  J Hum Genet. 2009
  PubMed ID: 19197335
   
  
• Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.
  Weidensdorfer D, Stöhr N, Baude A, Lederer M, Köhn M, Schierhorn A, Buchmeier S, Wahle E, Hüttelmaier S
  RNA. 2009
  PubMed ID: 19029303
   
  
• Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.
  Maggi LB, Kuchenruether M, Dadey DY, Schwope RM, Grisendi S, Townsend RR, Pandolfi PP, Weber JD
  Mol Cell Biol. 2008
  PubMed ID: 18809582
   
  
• Comparisons of RNAi approaches for validation of human RNA helicase A as an essential factor in hepatitis C virus replication.
  He QS, Tang H, Zhang J, Truong K, Wong-Staal F, Zhou D
  J Virol Methods. 2008
  PubMed ID: 18782589
   
  
• Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses.
  Fujimoto M, Oshima K, Shinkawa T, Wang BB, Inouye S, Hayashida N, Takii R, Nakai A
  J Biol Chem. 2008
  PubMed ID: 18755693
   
  
• Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
  Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
  Genome Res. 2008
  PubMed ID: 18799693
   
  
• A quantitative atlas of mitotic phosphorylation.
  Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
  Proc Natl Acad Sci U S A. 2008
  PubMed ID: 18669648
   
  
• The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA.
  Prahl M, Vilborg A, Palmberg C, Jörnvall H, Asker C, Wiman KG
  FEBS Lett. 2008
  PubMed ID: 18519039
   
  
• Guanine nucleotide depletion mediates translocation of nucleolar proteins, including RNA helicase A (DHX-9).
  Huang M, Mitchell BS
  Nucleosides Nucleotides Nucleic Acids. 2008
  PubMed ID: 18600529
   
  
• A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell.
  Hong Z, Jiang J, Lan L, Nakajima S, Kanno S, Koseki H, Yasui A
  Nucleic Acids Res. 2008
  PubMed ID: 18385154
   
  
• Toward a confocal subcellular atlas of the human proteome.
  Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
  Mol Cell Proteomics. 2008
  PubMed ID: 18029348
   
  
• Stimulation of the DNA unwinding activity of human DNA helicase II/Ku by phosphorylation.
  Ochem AE, Rechreche H, Skopac D, Falaschi A
  Arch Biochem Biophys. 2008
  PubMed ID: 18053790
   
  
• Functional role of Zic2 phosphorylation in transcriptional regulation.
  Ishiguro A, Aruga J
  FEBS Lett. 2008
  PubMed ID: 18068128
   
  
• Werner syndrome helicase (WRN), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome.
  Zhang S, Hemmerich P, Grosse F
  Cell Biol Int. 2007
  PubMed ID: 17498979
   
  
• Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
  Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B
  Mol Cell. 2007
  PubMed ID: 17643375
   
  
• RNA helicase A interacts with RISC in human cells and functions in RISC loading.
  Robb GB, Rana TM
  Mol Cell. 2007
  PubMed ID: 17531811
   
  
• ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
  Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ
  Science. 2007
  PubMed ID: 17525332
   
  
• Molecular composition of IMP1 ribonucleoprotein granules.
  Jønson L, Vikesaa J, Krogh A, Nielsen LK, Hansen T, Borup R, Johnsen AH, Christiansen J, Nielsen FC
  Mol Cell Proteomics. 2007
  PubMed ID: 17289661
   
  
• ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A.
  Ishiguro A, Ideta M, Mikoshiba K, Chen DJ, Aruga J
  J Biol Chem. 2007
  PubMed ID: 17251188
   
  
• Large-scale mapping of human protein-protein interactions by mass spectrometry.
  Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
  Mol Syst Biol. 2007
  PubMed ID: 17353931
   
  
• Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
  Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
  Cell. 2006
  PubMed ID: 17081983
   
  
• Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.
  Toretsky JA, Erkizan V, Levenson A, Abaan OD, Parvin JD, Cripe TP, Rice AM, Lee SB, Uren A
  Cancer Res. 2006
  PubMed ID: 16740692
   
  
• The DNA sequence and biological annotation of human chromosome 1.
  Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E
  Nature. 2006
  PubMed ID: 16710414
   
  
• Association of RNA helicase a with human immunodeficiency virus type 1 particles.
  Roy BB, Hu J, Guo X, Russell RS, Guo F, Kleiman L, Liang C
  J Biol Chem. 2006
  PubMed ID: 16527808
   
  
• The nuclear import of RNA helicase A is mediated by importin-alpha3.
  Aratani S, Oishi T, Fujita H, Nakazawa M, Fujii R, Imamoto N, Yoneda Y, Fukamizu A, Nakajima T
  Biochem Biophys Res Commun. 2006
  PubMed ID: 16375861
   
  
• Characterization of RNA helicase A as component of STAT6-dependent enhanceosome.
  Välineva T, Yang J, Silvennoinen O
  Nucleic Acids Res. 2006
  PubMed ID: 16914450
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• A human protein-protein interaction network: a resource for annotating the proteome.
  Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
  Cell. 2005
  PubMed ID: 16169070
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.
  Friedemann J, Grosse F, Zhang S
  J Biol Chem. 2005
  PubMed ID: 15995249
   
  
• WW domains provide a platform for the assembly of multiprotein networks.
  Ingham RJ, Colwill K, Howard C, Dettwiler S, Lim CS, Yu J, Hersi K, Raaijmakers J, Gish G, Mbamalu G, Taylor L, Yeung B, Vassilovski G, Amin M, Chen F, Matskova L, Winberg G, Ernberg I, Linding R, O'donnell P, Starostine A, Keller W, Metalnikov P, Stark C, Pawson T
  Mol Cell Biol. 2005
  PubMed ID: 16055720
   
  
• Actinomycin D induces histone gamma-H2AX foci and complex formation of gamma-H2AX with Ku70 and nuclear DNA helicase II.
  Mischo HE, Hemmerich P, Grosse F, Zhang S
  J Biol Chem. 2005
  PubMed ID: 15613478
   
  
• Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin.
  Wang Q, Zhang Z, Blackwell K, Carmichael GG
  Curr Biol. 2005
  PubMed ID: 15723802
   
  
• A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
  McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA
  BMC Dev Biol. 2005
  PubMed ID: 16033648
   
  
• Gene and alternative splicing annotation with AIR.
  Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
  Genome Res. 2005
  PubMed ID: 15632090
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
  Genome Res. 2004
  PubMed ID: 15489334
   
  
• RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.
  Tetsuka T, Uranishi H, Sanda T, Asamitsu K, Yang JP, Wong-Staal F, Okamoto T
  Eur J Biochem. 2004
  PubMed ID: 15355351
   
  
• Large-scale characterization of HeLa cell nuclear phosphoproteins.
  Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
  Proc Natl Acad Sci U S A. 2004
  PubMed ID: 15302935
   
  
• A functional interaction between RHA and Ubc9, an E2-like enzyme specific for Sumo-1.
  Argasinska J, Zhou K, Donnelly RJ, Hay RT, Lee CG
  J Mol Biol. 2004
  PubMed ID: 15312759
   
  
• Arginine methylation of RNA helicase a determines its subcellular localization.
  Smith WA, Schurter BT, Wong-Staal F, David M
  J Biol Chem. 2004
  PubMed ID: 15084609
   
  
• Identification of toposome, a novel multisubunit complex containing topoisomerase IIalpha.
  Lee CG, Hague LK, Li H, Donnelly R
  Cell Cycle. 2004
  PubMed ID: 15034300
   
  
• RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells.
  Zhong X, Safa AR
  J Biol Chem. 2004
  PubMed ID: 14769796
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
  Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
  Nature. 2004
  PubMed ID: 15057822
   
  
• Nuclear DNA helicase II (RNA helicase A) binds to an F-actin containing shell that surrounds the nucleolus.
  Zhang S, Köhler C, Hemmerich P, Grosse F
  Exp Cell Res. 2004
  PubMed ID: 14729462
   
  
• The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs.
  Villacé P, Marión RM, Ortín J
  Nucleic Acids Res. 2004
  PubMed ID: 15121898
   
  
• DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner.
  Zhang S, Schlott B, Görlach M, Grosse F
  Nucleic Acids Res. 2004
  PubMed ID: 14704337
   
  
• Complete sequencing and characterization of 21,243 full-length human cDNAs.
  Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
  Nat Genet. 2004
  PubMed ID: 14702039
   
  
• Transcriptome analysis of mouse stem cells and early embryos.
  Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS
  PLoS Biol. 2003
  PubMed ID: 14691545
   
  
• Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
  Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 14610273
   
  
• Selective regulation of gene expression by nuclear factor 110, a member of the NF90 family of double-stranded RNA-binding proteins.
  Reichman TW, Parrott AM, Fierro-Monti I, Caron DJ, Kao PN, Lee CG, Li H, Mathews MB
  J Mol Biol. 2003
  PubMed ID: 12946349
   
  
• A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
  Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 12904583
   
  
• RNA helicase A interacts with dsDNA and topoisomerase IIalpha.
  Zhou K, Choe KT, Zaidi Z, Wang Q, Mathews MB, Lee CG
  Nucleic Acids Res. 2003
  PubMed ID: 12711669
   
  
• Antithetic effects of MBD2a on gene regulation.
  Fujita H, Fujii R, Aratani S, Amano T, Fukamizu A, Nakajima T
  Mol Cell Biol. 2003
  PubMed ID: 12665568
   
  
• Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells.
  Schlegel BP, Starita LM, Parvin JD
  Oncogene. 2003
  PubMed ID: 12592385
   
  
• BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
  Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
  Nucleic Acids Res. 2003
  PubMed ID: 12520002
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• Initial sequencing and comparative analysis of the mouse genome.
  Mouse Genome Sequencing Consortium, Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, Barlow K, Beck S, Berry E, Birren B, Bloom T, Bork P, Botcherby M, Bray N, Brent MR, Brown DG, Brown SD, Bult C, Burton J, Butler J, Campbell RD, Carninci P, Cawley S, Chiaromonte F, Chinwalla AT, Church DM, Clamp M, Clee C, Collins FS, Cook LL, Copley RR, Coulson A, Couronne O, Cuff J, Curwen V, Cutts T, Daly M, David R, Davies J, Delehaunty KD, Deri J, Dermitzakis ET, Dewey C, Dickens NJ, Diekhans M, Dodge S, Dubchak I, Dunn DM, Eddy SR, Elnitski L, Emes RD, Eswara P, Eyras E, Felsenfeld A, Fewell GA, Flicek P, Foley K, Frankel WN, Fulton LA, Fulton RS, Furey TS, Gage D, Gibbs RA, Glusman G, Gnerre S, Goldman N, Goodstadt L, Grafham D, Graves TA, Green ED, Gregory S, Guigó R, Guyer M, Hardison RC, Haussler D, Hayashizaki Y, Hillier LW, Hinrichs A, Hlavina W, Holzer T, Hsu F, Hua A, Hubbard T, Hunt A, Jackson I, Jaffe DB, Johnson LS, Jones M, Jones TA, Joy A, Kamal M, Karlsson EK, Karolchik D, Kasprzyk A, Kawai J, Keibler E, Kells C, Kent WJ, Kirby A, Kolbe DL, Korf I, Kucherlapati RS, Kulbokas EJ, Kulp D, Landers T, Leger JP, Leonard S, Letunic I, Levine R, Li J, Li M, Lloyd C, Lucas S, Ma B, Maglott DR, Mardis ER, Matthews L, Mauceli E, Mayer JH, McCarthy M, McCombie WR, McLaren S, McLay K, McPherson JD, Meldrim J, Meredith B, Mesirov JP, Miller W, Miner TL, Mongin E, Montgomery KT, Morgan M, Mott R, Mullikin JC, Muzny DM, Nash WE, Nelson JO, Nhan MN, Nicol R, Ning Z, Nusbaum C, O'Connor MJ, Okazaki Y, Oliver K, Overton-Larty E, Pachter L, Parra G, Pepin KH, Peterson J, Pevzner P, Plumb R, Pohl CS, Poliakov A, Ponce TC, Ponting CP, Potter S, Quail M, Reymond A, Roe BA, Roskin KM, Rubin EM, Rust AG, Santos R, Sapojnikov V, Schultz B, Schultz J, Schwartz MS, Schwartz S, Scott C, Seaman S, Searle S, Sharpe T, Sheridan A, Shownkeen R, Sims S, Singer JB, Slater G, Smit A, Smith DR, Spencer B, Stabenau A, Stange-Thomann N, Sugnet C, Suyama M, Tesler G, Thompson J, Torrents D, Trevaskis E, Tromp J, Ucla C, Ureta-Vidal A, Vinson JP, Von Niederhausern AC, Wade CM, Wall M, Weber RJ, Weiss RB, Wendl MC, West AP, Wetterstrand K, Wheeler R, Whelan S, Wierzbowski J, Willey D, Williams S, Wilson RK, Winter E, Worley KC, Wyman D, Yang S, Yang SP, Zdobnov EM, Zody MC, Lander ES
  Nature. 2002
  PubMed ID: 12466850
   
  
• Functional proteomic analysis of human nucleolus.
  Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ
  Mol Biol Cell. 2002
  PubMed ID: 12429849
   
  
• A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.
  Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T
  J Biol Chem. 2002
  PubMed ID: 12171929
   
  
• The localization of nuclear DNA helicase II in different nuclear compartments is linked to transcription.
  Fuchsová B, Hozák P
  Exp Cell Res. 2002
  PubMed ID: 12243751
   
  
• Comprehensive proteomic analysis of the human spliceosome.
  Zhou Z, Licklider LJ, Gygi SP, Reed R
  Nature. 2002
  PubMed ID: 12226669
   
  
• Nuclear DNA helicase II is recruited to IFN-alpha-activated transcription sites at PML nuclear bodies.
  Fuchsová B, Novák P, Kafková J, Hozák P
  J Cell Biol. 2002
  PubMed ID: 12163469
   
  
• PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays.
  Lee J, Bedford MT
  EMBO Rep. 2002
  PubMed ID: 11850402
   
  
• The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription.
  Westermarck J, Weiss C, Saffrich R, Kast J, Musti AM, Wessely M, Ansorge W, Séraphin B, Wilm M, Valdez BC, Bohmann D
  EMBO J. 2002
  PubMed ID: 11823437
   
  
• Nuclear DNA helicase II/RNA helicase A binds to filamentous actin.
  Zhang S, Buder K, Burkhardt C, Schlott B, Görlach M, Grosse F
  J Biol Chem. 2002
  PubMed ID: 11687588
   
  
• Mapping the functional domains of HAP95, a protein that binds RNA helicase A and activates the constitutive transport element of type D retroviruses.
  Yang JP, Tang H, Reddy TR, Wong-Staal F
  J Biol Chem. 2001
  PubMed ID: 11402034
   
  
• Dual roles of RNA helicase A in CREB-dependent transcription.
  Aratani S, Fujii R, Oishi T, Fujita H, Amano T, Ohshima T, Hagiwara M, Fukamizu A, Nakajima T
  Mol Cell Biol. 2001
  PubMed ID: 11416126
   
  
• Reactivity of anti-proliferating cell nuclear antigen (PCNA) murine monoclonal antibodies and human autoantibodies to the PCNA multiprotein complexes involved in cell proliferation.
  Takasaki Y, Kogure T, Takeuchi K, Kaneda K, Yano T, Hirokawa K, Hirose S, Shirai T, Hashimoto H
  J Immunol. 2001
  PubMed ID: 11254741
   
  
• Functional annotation of a full-length mouse cDNA collection.
  Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
  Nature. 2001
  PubMed ID: 11217851
   
  
• A functional interaction between the survival motor neuron complex and RNA polymerase II.
  Pellizzoni L, Charroux B, Rappsilber J, Mann M, Dreyfuss G
  J Cell Biol. 2001
  PubMed ID: 11149922
   
  
• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
  Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
  Genome Res. 2000
  PubMed ID: 11076861
   
  
• Specific interaction between RNA helicase A and Tap, two cellular proteins that bind to the constitutive transport element of type D retrovirus.
  Tang H, Wong-Staal F
  J Biol Chem. 2000
  PubMed ID: 10924507
   
  
• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
  Genome Res. 2000
  PubMed ID: 11042159
   
  
• Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNA.
  Reddy TR, Tang H, Xu W, Wong-Staal F
  Oncogene. 2000
  PubMed ID: 10951562
   
  
• A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport element.
  Westberg C, Yang JP, Tang H, Reddy TR, Wong-Staal F
  J Biol Chem. 2000
  PubMed ID: 10748171
   
  
• A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting.
  Frank D, Mendelsohn CL, Ciccone E, Svensson K, Ohlsson R, Tycko B
  Mamm Genome. 1999
  PubMed ID: 10594239
   
  
• Nucleolar localization of murine nuclear DNA helicase II (RNA helicase A).
  Zhang S, Herrmann C, Grosse F
  J Cell Sci. 1999
  PubMed ID: 10413677
   
  
• The carboxyl terminus of RNA helicase A contains a bidirectional nuclear transport domain.
  Tang H, McDonald D, Middlesworth T, Hope TJ, Wong-Staal F
  Mol Cell Biol. 1999
  PubMed ID: 10207077
   
  
• A role for RNA helicase A in post-transcriptional regulation of HIV type 1.
  Li J, Tang H, Mullen TM, Westberg C, Reddy TR, Rose DW, Wong-Staal F
  Proc Natl Acad Sci U S A. 1999
  PubMed ID: 9892698
   
  
• The human RNA helicase A (DDX9) gene maps to the prostate cancer susceptibility locus at chromosome band 1q25 and its pseudogene (DDX9P) to 13q22, respectively.
  Lee CG, Eki T, Okumura K, Nogami M, Soares Vda C, Murakami Y, Hanaoka F, Hurwitz J
  Somat Cell Mol Genet. 1999
  PubMed ID: 10925702
   
  
• High-efficiency full-length cDNA cloning.
  Carninci P, Hayashizaki Y
  Methods Enzymol. 1999
  PubMed ID: 10349636
   
  
• RNA helicase A is essential for normal gastrulation.
  Lee CG, da Costa Soares V, Newberger C, Manova K, Lacy E, Hurwitz J
  Proc Natl Acad Sci U S A. 1998
  PubMed ID: 9811865
   
  
• Cloning of 5'-flanking region and a polymorphic CTT trinucleotide repeat within 5'-untranslated region of mouse R-type calcium channel alpha1-subunit (Cchra1) gene, and its genetic mapping.
  Yamazaki K, Oki T, Tanaka I
  Gene. 1998
  PubMed ID: 9651528
   
  
• BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.
  Anderson SF, Schlegel BP, Nakajima T, Wolpin ES, Parvin JD
  Nat Genet. 1998
  PubMed ID: 9662397
   
  
• Molecular analysis of the cDNA and genomic DNA encoding mouse RNA helicase A.
  Lee CG, Eki T, Okumura K, da Costa Soares V, Hurwitz J
  Genomics. 1998
  PubMed ID: 9480750
   
  
• Identification of DNA replication and cell cycle proteins that interact with PCNA.
  Loor G, Zhang SJ, Zhang P, Toomey NL, Lee MY
  Nucleic Acids Res. 1997
  PubMed ID: 9396813
   
  
• Intrathymic education of alpha beta and gamma delta T cells is accompanied by cell surface expression of RNA/DNA helicase [corrected]
  Miazek A, Brockhaus M, Langen H, Braun A, Kisielow P
  Eur J Immunol. 1997
  PubMed ID: 9464815
   
  
• RNA helicase A mediates association of CBP with RNA polymerase II.
  Nakajima T, Uchida C, Anderson SF, Lee CG, Hurwitz J, Parvin JD, Montminy M
  Cell. 1997
  PubMed ID: 9323138
   
  
• Domain structure of human nuclear DNA helicase II (RNA helicase A).
  Zhang S, Grosse F
  J Biol Chem. 1997
  PubMed ID: 9111062
   
  
• Leukophysin: an RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles.
  Abdelhaleem MM, Hameed S, Klassen D, Greenberg AH
  J Immunol. 1996
  PubMed ID: 8690889
   
  
• Human RNA helicase A is homologous to the maleless protein of Drosophila.
  Lee CG, Hurwitz J
  J Biol Chem. 1993
  PubMed ID: 8344961
   
  
• RNA annealing activity is intrinsically associated with U2AF.
  Lee CG, Zamore PD, Green MR, Hurwitz J
  J Biol Chem. 1993
  PubMed ID: 7685763
   
  
• A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' direction.
  Lee CG, Hurwitz J
  J Biol Chem. 1992
  PubMed ID: 1537828
   
  

Relevant resources:

Comment on this Page
Privacy Statement  |   Copyright, Warranty & Disclaimer  |   Contact Us
Copyright © 2001-2011, T1DBase | Version 4.8 | PMID:20937630
Printed on Fri February 10, 2012